31 Oct. 2006 NBCEC Brown Bagger R.L. Quaas

DNA Test Validation Update

Dick Quaas Cornell University

31 Oct. 2006 NBCEC Brown Bagger R.L. Quaas

Quantitative Trait DNA Tests Available

Bovigen GeneSTAR® ... Report # Stars & GEPD1. GeneSTAR® Tenderness (3 SNP)2. GeneSTAR® Quality Grade (4 SNP)3. GeneSTAR® Feed Efficiency (4 SNP)

IGENITY® Profile ... 1-10 score1. IGENITY® Tenderness (3 SNP)2. IGENITY® Carcass Composition (5-10 SNP)

MMI ... MGV1. Tru-Marbling™ (128 SNP)2. Tru-Tenderness™ (11 SNP)

31 Oct. 2006 NBCEC Brown Bagger R.L. Quaas

Bovigen GeneSTAR®http://www.bovigen.com/products

1. GeneSTAR® Quality Grade Marbling ScoreNBCEC

2. GeneSTAR® Tenderness14d WBSFNBCEC

3. GeneSTAR® Feed EfficiencyIntake (NFI=RFI?) not feed efficiencyNo request for validation

31 Oct. 2006 NBCEC Brown Bagger R.L. Quaas

IGENITY® Profilehttp://www.igenity.com/

IGENITY® CarcassComposition

Ribeye area Quality grade (MS)Hot carcass weight Yield grade Fat thickness

Analyses in progress

IGENITY® Tenderness14d WBSFNBCEC

Feed intake/RFI panel being analyzed

31 Oct. 2006 NBCEC Brown Bagger R.L. Quaas

MMIhttp://www.mmigenomics.com/

products1.html

Tru-Marbling™ & Tru-Tenderness™

MMI reported AAA CMP data analysis @ NCBA (see MMI website)

NBCEC subsequently analyzed these data

31 Oct. 2006 NBCEC Brown Bagger R.L. Quaas

NBCEC AAA CMP Analyses(not validation)

Estimates  Variance

ComponentsVariance Reduction

  b SE p Residual Sire Residual Sire "h2"

1:MS=CG+e 7422

2:MS=CG+b x MGV+e 0.47 0.14 1.3E-03 7239 2.5%

3:MS=CG+b x MGV+Sire+e 0.45 0.15 3.1E-03 6761 915 2.0% 5.1% 0.48

4:MS=CG+Sire+e       6901 964     0.49

                 

1:WBSF=CG+e 2.13

2:WBSF=CG+b x MGV+e 0.50 0.09 2.6E-08 1.97 7.8%

3:WBSF=CG+b x MGV+Sire+e 0.50 0.09 7.6E-08 1.87 0.21 7.2% 19.7% 0.41

4:WBSF=CG+Sire+e       2.02 0.27     0.47

31 Oct. 2006 NBCEC Brown Bagger R.L. Quaas

NBCEC AAA CMP Analyses(not validation)

Estimates  Variance

ComponentsVariance Reduction

  b SE p Residual Sire Residual Sire "h2"

1:MS=CG+e 7422

2:MS=CG+b x MGV+e 0.47 0.14 1.3E-03 7239 2.5%

3:MS=CG+b x MGV+Sire+e 0.45 0.15 3.1E-03 6761 915 2.0% 5.1% 0.48

4:MS=CG+Sire+e       6901 964     0.49

                 

1:WBSF=CG+e 2.13

2:WBSF=CG+b x MGV+e 0.50 0.09 2.6E-08 1.97 7.8%

3:WBSF=CG+b x MGV+Sire+e 0.50 0.09 7.6E-08 1.87 0.21 7.2% 19.7% 0.41

4:WBSF=CG+Sire+e       2.02 0.27     0.47

31 Oct. 2006 NBCEC Brown Bagger R.L. Quaas

NBCEC AAA CMP Analyses(not validation)

Estimates  Variance

ComponentsVariance Reduction

  b SE p Residual Sire Residual Sire "h2"

1:MS=CG+e 7422

2:MS=CG+b x MGV+e 0.47 0.14 1.3E-03 7239 2.5%

3:MS=CG+b x MGV+Sire+e 0.45 0.15 3.1E-03 6761 915 2.0% 5.1% 0.48

4:MS=CG+Sire+e       6901 964     0.49

                 

1:WBSF=CG+e 2.13

2:WBSF=CG+b x MGV+e 0.50 0.09 2.6E-08 1.97 7.8%

3:WBSF=CG+b x MGV+Sire+e 0.50 0.09 7.6E-08 1.87 0.21 7.2% 19.7% 0.41

4:WBSF=CG+Sire+e       2.02 0.27     0.47

31 Oct. 2006 NBCEC Brown Bagger R.L. Quaas

MMIhttp://www.mmigenomics.com/

products1.html

Tru-Marbling™ & Tru-Tenderness™

MMI analyzed AAA CMP data (see MMI website)

NBCEC also analyzed these dataNot independent validation

Awaiting genotypes from MMI of ISU Angus for validation

31 Oct. 2006 NBCEC Brown Bagger R.L. Quaas

NBCEC Web Site

http://www.nbcec.org/nbcec/

Click on validation tab for most recent results.