Upload
darrell-noel-norman
View
218
Download
0
Tags:
Embed Size (px)
Citation preview
Robert Scranton© 2008
5 Cardinal Signs of InflammationHeatRednessSwelling/ EdemaPainLoss of Function
Vascular DilationVascular DilationExudateAfferent InformationA result of the
edema and pain
Caused By?
InflammationAcute Chronic
Neutrophil
No
Neutrophil
Lymphocytes, monocytes, eosinophils
Yes
Lymphocytes (also macrophages)
Cell type:
Angiogenesis:
Hallmark:
InflammationMast Cell NeutrophilIgE
Heparin, Histamine & SRS-A
Around small bv, external epithelia
IgG & complement
Primary granules= Lysozyme & myeloperoxidaseSecondary Granules= alkaline phosphataseTertiary Granules= gelatinase
• intravascular
Receptor:
Contents
Location
Special Neutrophil infoLife span?When dead after
responding to inflammation, they become?
How do neutrophils survive in devascularized tissue?
Explain the process by which they get into the area of inflammation.
Margination
Rolling
Diapedesis
MacrophageDerived from?Surface receptor
types?Activated
macrophages look ________.
What happens when many macrophages surround large foreign bodies?
Functions
LymphocytesNuclear/cytoplasmic
ratio?Cell mediated=?Humoral= ?
EosinophilsPhagocytic activitySurface receptors
for?How does it attack
parasites?Granules, what type?
=
BasophilsReceptors forDiscuss slow and fast
granule releaseGranules contain?
ReconstructionDays?Fibroblasts+
vascular endothelial cells= ?
What are the characteristics of granulation tissue?
What happens after reconstruction?
Primary v. secondary union
RemodelingTime periodTypical maximal
tensile strength of the CT is?