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Lipid Metabolism

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Lipid Metabolism

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Lipid Metabolism

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Lipid Metabolism

Digestion - Hydrolysis Reaction

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Lipid Metabolism

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Lipid Metabolism

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Fatty Acid Oxidation

Initial Step: Requires an ATP to synthesize acetyl

CoA with the fatty acid.

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Beta Oxidation

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Beta Oxidation

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Beta Oxidation

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Beta Oxidation

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Beta Oxidation

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Beta Oxidation

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Beta Oxidation

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Palmitic Acid Review

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Palmitic Acid -ATP Synthesis

Palmitic Acid is C-16

Initiating Step - requires 1 ATP (text says 2) Step 1 - FAD into e.t.c. = 2 ATP

Step 3 - NAD+ into e.t.c. = 3 ATP

Total ATP per turn of spiral = 5 ATP Example with Palmitic Acid = 16 carbons = 8

acetyl groups

Number of turns of fatty acid spiral = 8-1 = 7 turns

ATP from fatty acid spiral = 7 turns and 5 per turn

= 35 ATP.

NET ATP from Fatty Acid Spiral = 35 - 1 = 34

ATP

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Palmitic Acid (C-16) -ATP Synthesis

NET ATP - Fatty Acid Spiral = 35 - 1 = 34 ATP

Review ATP - Citric Acid Cycle start with Acetyl CoA Step ATP produced

7 visible ATP 1

Step 4 (NAD+ to E.T.C.) 3

Step 6 (NAD+ to E.T.C.) 3 Step10 (NAD+ to E.T.C.) 3

Step 8 (FAD to E.T.C.) 2

NET 12 ATP per turn C.A.C. 8 Acetyl CoA = 8 turns C.A.C.

8 turns x 12 ATP/C.A.C. = 96 ATP

GRAND TOTAL 130 ATP

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Acetyl CoA

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Ketone Bodies

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Ketone Bodies

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Blood Glucose and Glucosuria

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Ketone Bodies

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Lipogenesis