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2005
Pyridine derivativesR 0380 SAR and Biological Evaluation of Novel trans-3,4-Dimethyl-4-arylpiperidine De-
rivatives as Opioid Antagonists. — Compound (XVI) improves the pharmacokinetic properties of LY 255582 and is also efficacious in reducing food consumption in rats. — (DIAZ*, N.; et al.; Bioorg. Med. Chem. Lett. 15 (2005) 17, 3844-3848; Lilly Spain S.A., E-28108 Alcobendas, Madrid, Spain; Eng.) — C. Oppel
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