SCHEME OF INSTRUCTION, EXAMINATION AND …gprcp.ac.in/syllabusmp/Pharm Pharmaceutics Scheme - CBCS.pdfProgram Code: 886 M. Pharm. (Pharmaceutics) 2015 – 16 SEMESTER - I Course Code

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G.Pulla Reddy College of Pharmacy

Hyderabad

Osmania University

1Chairperson, BoS Head of the Department Dean of the Faculty

SEMESTER - II

SEMESTER – III

SCHEME OF INSTRUCTION, EXAMINATION AND EVALUATION Program Code: 886 M. Pharm. (Pharmaceutics)

2015 – 16

SEMESTER - I

Course Code Course Title Hours /Week Credits Marks Durationof Exam L T P Internal End Exam

PY.09.884.11.T Pharmaceutical Analytical Techniques 3 0 - 3 25 75 3 PY.09.886.12.T Pharmaceutical Product Development 4 0 - 4 25 75 3 PY.09.886.13.T Pharmaceutical Production Technology 4 0 0 4 25 75 3 PY.09.886.14.T Advanced Physical Pharmaceutics 4 0 0 4 25 75 3 PY.09.885.15.T Quality Assurance 3 0 0 3 25 75 3 PY.09.884.11.P Pharmaceutical Analytical Techniques - 0 4 2 25 75 6 PY.09.886.12.P Pharmaceutical Product Development - 0 4 2 25 75 6 22 175 525 PY.09.886.10.S SAIL 1 2 0 2 Grade PY.09.886.11.S Seminar 1 0 2 2 Grade

Course Code Course Title Hours /Week Credits Marks Durationof Exam L T P Internal End Exam

PY.09.885.21.T Int. Property Rights & Regulatory Affairs 3 0 - 3 25 75 3 PY.09.886.22.T Biopharmaceutics and Pharmacokinetics 4 0 - 4 25 75 3 PY.09.886.23.T Advances in Drug Delivery System 4 0 0 4 25 75 3 PY.09.886.24.T Process Scale Up and Validation 4 0 0 4 25 75 3 PY.09.88X.25.T Elective * 3 0 0 3 25 75 3 PY.09.886.22.P Biopharmaceutics and Pharmacokinetics - 0 4 2 25 75 6 PY.09.886.23.P Advances in Drug Delivery System - 0 4 2 25 75 6 22 175 525 PY.09.886.20.S SAIL 1 2 0 2 Grade PY.09.886.21.S Seminar 1 0 2 2 Grade * Discipline Centric – Cosmetic Technology/Drug Polymer Technology; Open – Pharmaceutical Biotechnology

Course Code Course Title Hours /Week Credits Marks Duration in Weeks Internal External

PY.10.886.31.P Design Seminar 30 6 50 - 6 PY.10.886.32.P Progressive Seminar 30 10 50 - 10

480 16 100

SEMESTER – IV

Course Code Course Title Hours /Week Credits Marks Durationin Weeks Internal External

PY.10.886.41.P Pre-Submission Seminar 30 10 50 10 PY.10.886.42.P Submission and Adjudication 30 12 200 6 PY.10.886.43.P Final Viva-voce 30 2 50 1

510 24 300 17

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2

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Scheme of Total DuratiHours/WeekCredits Instruction MCourse CodCourse ObjTo familiarize To understandTo give traininTo build on th

Course OuBy pursuing th

- Rese- Food- Clinic

Unit - I :UV-Visible Sp(electronic traInstrumentatioillustrating themulticomponehydrocarbonsInfra-Red SpInstrumentatiohandling for IR

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PHARMA

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ACEUTICA

60 Hrs. 3 Hrs. 3 Lecture PY.09.884.1

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nation 100 20 05 75 3 Hrs.

pharmacy. ntrol lab.

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s including unsaturated

on bonds. s. Sample ectance).

ncept, spin- multiplicity

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Unit

ElectElectElectRadi

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A Textbook of Perritt LL, Dean ew Delhi, 1986mpman GM, Klifornia, 2008. strumental Met

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X-rays, basic asiffraction, powd: Principles, Th

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lectrophoresis ative) and Ca

ler indices, rotapplications. SC, DTAand T

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4

Osmania Univ

Scheme of Total DuratiHours/WeekCredits Instruction MCourse Cod

Course ObjThis subject imThe student lsubstances an

Course OuThe students aphysical and aware ofvarioformulation of

Unit - I :Pre-formulatihygroscopicityDesign of Exand Products

Unit - II :Formulation flavoring agenpharmaceutic

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Unit - III :Solubility: Imsolubility, phasSolvency, SaDissolution: Factors influetesting for comedia, in-vitro

Unit - IV :Chemical StaStability TestinProduct Stabinfluencing-meTablets). Phot

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PHARMA


: Mode :

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tcomes: after undergoinpharmaceutica

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BoS

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theoretical knoarious physicao be studied an

ng their courseal properties ofs to be studied armaceuticals;

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of Examinaarks :

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pharmaceuticn of kinetic da

cols and Repor

he Faculty

ation 100 20 05 75 3 Hrs.

its stability. erials, drug

e ofvarious all become e optimized

salts and

of Materials

oloring and uents and

nts, directly pients, flow

on, intrinsic iques, Co-

d non-sink. dissolution

Bio -relevant

cal Stability,

cals, factors ata (API & rts;


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UnitGeneAct, DeveNoveNano

Boo1.

2. 3.

4.

5. 6.

7.

8.

9. 10. 11.

12.

13. 14. 15.

person BoS

t - V : eric Drug ProBolar Amend

elopment, Geneel Products Do-gels, Nano-c

oks and RefeLachman L, LPublishers, MSinko PJ. MarLieberman HAPublishers & Conners KA. PhysicochemYalkowsky SHDressman J, K

Sethi PD. QuaDelhi, 2008. Carstensen JTNew Delhi, 20Yoshioka S, SBanker GS, RW. Grimm - SPvt. Ltd., BanBeckett AH, SDistributors, NIndian PharmBritish PharmUnited States

ducts: Generadment, Principeric Drug Prod

Development: arrier Systems

erences: ieberman HA, umbai 1991.

rtin's Physical PA, Lachman L,Distributors, Ne A Text book ical Properties

H. T echniques Kramer J. Phar

antitative Analy

T, Rhodes CT. 005. Stella VJ. StabiRhodes CT. MoStability Testinggalore, 1999. Stenlake JB. P

New Delhi, 200acopoeia. Conacopoeia. Briti Pharmacopoe

Head of th

al Principles, Caples of Excluduct Approval. Nano-Pharma

s;

Kanig JL. The

Pharmacy& Ph Schwartz JB. ew Delhi, 2005 of pharmace

s of Drug Subs of Solubilizatiormaceutical Dis

sis of Drugs in

Drug StabilityP

lity of Drugs anodern Pharmacg of Drug Prod

Practical Pharm04. ntroller of Publish Pharmacopeia. United Sta

he Departme

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ceuticals - Ge

Theoryand Pr

armaceutical S Pharmaceutic5. utical analysi Wtances. Ellis Hon of Drugs. Vossolution T estin

n Pharmaceutic

Principles and

nd Dosage Forceutics, 4th Ed.

ducts. Mazzo D

maceutical Che

ication. Delhi, poeia Commistes Pharmaco

nt

UT of Patent PRegulations –

neration and S

ractice of Indus

Sciences, 5th Edcal dosage form

Wells JI. PhaHarwood Ltd., Eol-12. Marcel Dng. Saurabh P

calFormulations

Practices, 3rd E

rms, Springer (, Marcel Dekke

DJ. Internationa

emistry, Part I

1996. ssion Office, Lopoeial Conven

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Pharmaceutica– ANDA, Gen

Significance of

strial Pharmacy

d., B.I. Pub. Pvtms: tablets Vo

rmaceutical PrEngland, 1998.Dekker Inc. Nerinter Pvt. Ltd.,

rd s, 3 edn., CBS

Ed., CBSPublis

(India) Pvt. Ltd.er Inc., New Y

al Stability T est

& II. 4th Ed.,

ondon,2008. ntion, Inc, USA,

e Faculty

Osmania Univ

als, Hatch - Waeric Drug Pr

f Nano-suspens

y, 3rd Ed, Vargh

t. Ltd, Noida, 2ol. I-II, 2nd Ed., C

re-formulation: w York, 1981. New Delhi, 20

S Publications

shers & Distribu

., New Delhi, 20York, 2005.

ting. Eastern P

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, 2003.

5

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axman roduct

sions,

hese

006. CBS

The

005..

, New

utors,

006.

Press

rs &


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6

Osmania Univ

P


Course ObjThe students requirements concerns.

Course OuThe students scapsules, dispsafety and pol

Unit - I :Improved Tapalletization eand marumerCoating TecProblems enc

Unit - II :Parenteral Pmachineries, maintenance. Lyophilizatio

Unit - III :Capsule Prodsoft gelatin caDisperse Sysincluding fine

Unit - IV :Packaging Teplastics, metastrips and sacaspects of pa

Unit - V Air Handling Pharmaceutictreatment-Ion

Books and 1. The theor

Chairperson

versity

PHARMAC


: Mode :

de :

jectives: are given the and special em

tcomes: should be ableperse systems,llution, present

: ablet Productiquipment, contisers, and othehnology: Proccountered.

: Production: A

change room

on Technolog

: duction: Produapsules. Layoustems Produc solids dispers

: echnology: Thls, films, foils a

chetpackagingckaging.

: Systems: Stucal Water Sysexchange, reve

Referencesry & Practice o

BoS

CEUTICA


e emphasis onmphasis on th

e to explain the describe specting them with s

ion: Tablet ptinuous and baer specialized gcess, equipme

Area planning ms, personnel

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s: f Industrial Pha

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commercial prcial requiremenspecific progra

roduction procatch mixing, ragranulation andent, particle co

& environmel flow, utilitie

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, improved capms encounteredction processes Encountered.

unction, types os. Closures and

harmaceutical p

umidity & temps, pretreatmentRO), distillation

armacy, L. Lac

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UCTION

ion activities o process probl

roduction activnts for the par

ams in pharmac

cess, unit opepid mixing grad drying equip

oating, fluidized

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of packaging md closuresystepackages, pack

perature controt, techniques an, ultrafiltration

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TECHNO


of pharmaceutlems, including

vities of differenrenteral producceutical industr

eration improveanulators, rota gment. Problemd bed coating

wall and floor equipment lo

ipment.

turing and fillin

s of mixers, m

materials, papem, packaging mkage printing a

ol, air filtration nd maintenanc, qualitycontrol

ese Publ, Bomb

Dean of th

OLOGY

e of ExaminMarks :

mester ::

mester :Duration :

tical industry wg safety and e

ntdosage formscts, evaluate thry.

ements, granugranulators, spms encountereg, application t

treatment, fixcation, engine

g machines fo

mills, disperse

r and board bamachineryinclu

and decoration

systems, dust ce; types of wa, storage & dis

bay.

he Faculty

nation 100 20 05 75 3 Hrs.

with general nvironment

s of tablets, he status of

ulation and pheronizers d. techniques.

xtures and eering and

r hard and

equipment

ased, glass, uding blister , regulatory

collectors. aters; water stribution.


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2. M3. P4. P5. P6. D7. P8. P9. P10. 11. 12. T

person BoS

Modern PharmPharmaceuticaPharmaceuticaPharmaceuticaDispersed SystProduct DesignPharmaceuticaPackaging PhaQuality ControlFreeze Drying/Tablet Machin

maceutics by Baal Dosage Formal Dosage Formal Production Ftem Vol 1, 2, 3 n and Testing oal Project Manaarmaceutical al of Packaging /Lyophilization one Instrumenta

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he Departme

Marcel Dekkerby Lachman, L

Medications, Vgn and ApplicaLieberman, Ma

Materials by N.Pennedy, Vol 86

re, H. LockhardPharmaceuticaticals & Biologicaceuticals, PR

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arcel Dekker, NE. Avis, Marcel

Cole, TaylorNY. off. ker, NY.

arburn, Marcel . Ray, Vol 96, Mrwood’s, UK.

e Faculty

Osmania Univ

NY. Dekker, NY. r and Francis.

Dekker, NY. Marcel Dekker,

7

versity

NY.


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8

Osmania Univ


Course ObjThe students judicious appliin order to con

Course OuThe students nanoparticles and processesthe design, ev

Unit - I :Viscoelasticitmodeling of vAdvanced Meindividual partDrug Deliver

Unit - II :Physics of TLoads Forcesenergy involvecompression,

Unit - III :Surfactant Sybehavior; Miceand kinetics system, interasurfactants in of membranes

Unit - IV Polymers – Ppolymerizationpreparation ofcharacterizatiomorphology. Polymers – Systems (HBSpolymer matridrug delivery s

Chairperson

versity

ADVA


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BoS

ANCED P

60 Hrs. 4 Hrs. 4 Lecture PY.09.886.

training on thedesign of produdevelopment o

le to explain ttic behavior of rcompression; ethe efficient rel

testing and bepsycho-rheologrticle Size Disontacted particetic hydrogels-

neral principleduring Comprection, propertiesompression fo

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e physical anduct and develoof drugs.

the principles arawmaterials a

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nt

MACEUTI

SchemeMax. MaMid SemQuizEnd SemExam Du

perties of drugfacilitates the e

for evaluation The students shproperties of pl drug delivery

ng and behav

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properties of sw

on, decompresorces in compon, properties ets

nary systems. CMC and micebilization, Solubes. Hydro trocton: dissolutiusion complex

ntroduction, , cpolymer solu

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Dean of th

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of Examinaarks :

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of particle sizehould describe olymer and the systems.

vior analysis, m

e, shape and

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classification oftions (solvent

croencapsulatioperties, crysta

dro-dynamically-erodible polymgradable polym

he Faculty

ation 100 20 05 75 3 Hrs.

rs, for their se of drugs

e including the factors eir utility in

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on at High asurement,

achinery for

cting phase modynamics on-aqueous

maceuticals, permeability vents

f polymers, selection, on, polymer allinity, and

y Balanced mers, drug mers, colon


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UnitDrugreleaswellCons

Boo1. A. 2. A. 3. D. 4. G.5. H. 6. J. 7. Ja8. Lie9. M.10. M11. N

12. P13. P14. R

person BoS

t - V g Release Mease, diffusion mling matrix sysiderations

oks and Refe Kitahard and Martin, P. Bus M. Parikh; Ha Alderborn and G. Brittain; PhT. Cartensen; mes J. Wells;

eberman, Ries. N. RubinsteinMartin Rhodes;N. G. Stanley –

P. H. List and PP. J. Tarcha; PRobinson; Nove

chanisms – methods (Modeystems, osmoti

erences: A. Watanabe; E

stamante and Aandbook of Phad C. Nystrom; Physical Charact Drug Stability; Pharmaceuticaer and Banker

n; Pharmaceuti Principles of P– Wooed; Enla

P. C. Schmidt; Polymer for Conel Drug Deliver

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Electrical PhenA. H. Chun; Phyarmaceutical GPharmaceuticaterization of Ph Marcel Dekkeal Preformulatir; Pharmaceuticcal TechnologPowder Technargement and

Pharmaceuticantrolled Drug Dry Systems, Ma

he Departme

Modeling: Disusion release mctivated system

nomena at Inteysical Pharmac

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al TechnologyDelivery, CRC Parcel Dekker.

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ssolution releamodeling – m

ms, drug releas

erfaces; Marcecy; Waverly. chnology; Mar

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ood Ltd. orms; Dispersety, John Wiley a

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, CRS Press. Press.

Dean of th

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ase modeling, matrix systems,

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l Dekker.

rcel Dekker. nology; Marce Dekker.

e system; Marcand sons. ds; Butterwort

e Faculty

Osmania Univ

diffusion med, reservoir sysomparison, pra

l Dekker.

cel Dekker.

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9

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10


Course ObjAchieve comstandards syDevelop and i

Course OuThis subject is

- Acquirerelated

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seller, India, 19

allabh Prakas

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990.

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Course ObjTo make studinstruments in

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14

INTELLE


Course ObjTo make stude

Course OuOn completionRegulatory AffFurther to famSustainable D

Unit - I :Intellectual Ppatentable, Igeographical India Patentsmaintaining th

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UnitInduMechFire PolluEnvirOtheSust

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t - V strial Safety hanical, Electricand Explosionution Control ronmental Polluer Product Retainable Deve

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B

Scheme of Total DuratiHours/WeekCredits Instruction MCourse CodCourse ObjTo make studexcretion of drTo emphasize

Course OuOn completion

- Drug - Basic- How

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Unit - I :Bioavailabilitenhancing bioMethods of deDrug Distribudifferent plots

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olism and

d physical

oavailability, quivalence.

nstants &

ment, multi and other t, design of

in renal &

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ns. d, different


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3. Th4. Cl5. Bio6. Re7. Bio8. C

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person BoS

heory & Practicinical Pharmacopharmaceuticemingtons Phaopharmaceutic.V.S.Subrahmaelhi.

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Dean of th

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Osmania Univ

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Vallabh Prakas

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18


Course ObjTo get acquain

Course OuStudents can knowledge gain Pharma ind

Unit - I :Concept & Mrelease, activadelivery, compDDS – intermi

Unit - II :Study of Varadhesive DDS

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person BoS

6. Drug Delive7. Polymers fo8. Pharmaceu9. Biotechnolo10. Protein For11. Drug Targe

ery Devices, Voor Controlled Dutical Biotechnoogy of Industriarmulation & Deeting, M.H. Rub

Head of th

ol 32, P Tyle MDrug Delivery, Pology, Vyas, CB

al Antibiotics, Eelivery, E.J. McNbinstein, John

he Departme

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nt

NY. RC Press.

e, Marcel DekkMarcel Dekker

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Dean of th

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Osmania Univ

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versity

19


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20

Scheme of Total DuratiHours/WeekCredits Instruction MCourse CodCourse ObjTo enable the

Course OuTo apply their

Unit – I Scale Up Tec(emulsificationsize reduction

Unit – II Pharmaceuticpharmaceuticasolution dosag

Unit – III Validation: GAnalytical M

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Unit – V Process Validfilling and seaInventory Coobtain I & E li

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PRO


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ing, compressicontrol. Export regulatiopectives and V

el Dekker, NY. ations, Taylor aDekker, NY.

Pharmacy, VargWiley.

lets, Vol 1, 2, 3Vol 1, 2 Marceel Dekker, NY. ent, 2007, Vallaw Hill, India.

Dean of th

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e of ExaminMarks :

mester ::

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alidation

nal analysis, miblets– mixing, gard gelatin cap

development, Plant- tablets,renteral produc

ation master filearatus.

S, membrane fsealing machin

ning Validation.

on, tablet coat

ons laws and mVendor Qualifica

and Francis.

ghese Publ. Bo

3 by Marcel Del Dekker, NY.

abh Prakashan,

he Faculty

nation 100 20 05 75 3 Hrs.

crospheres granulation, psules,

layout of capsules, cts.

e (VMF).

filter, rapid ne. .

ing, liquid

methods to ation.

ombay.

ekker, NY.

, Dehli


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Hyderabad

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t – II : el Approacheoparticles, iontorapeutic Ingredperformance e

bal Cosmeticseem in various

t – III : siological Coology of Cosdorants, hair prufacturing Tekaging: Packa

t – IV : lity Standards

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es in Cosmeophoresis, to edients in vario

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Head of th

E

COSMETI

Hrs.rs.

ure09.886.25.T

s parameters in

epts and factors

meticFormulatiemulsifiers, thervatives; Coloects of colors materials in prfumery, analyton of perfumeetics.

tic Formulatinhance functioous Cosmeticshese activities. s in use of herducts

Skin, Hair, Naiological additives and lotions. osmetic creament and design

Products: Quty of Cosmetic Textural Analus cosmetic pdentifrices. Desmetic products

he Departme

ELECTIVE

IC TECH

nvolved in the f

s influencing th

ons: Overviewickeners, hydroring agents usw.r.t. cosmetic

perfumery, devtical and sepa

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l and Eye- in res in cosmeti

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nt

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formulation and

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w of raw materiarocolloids, polysed in cosmet products; veloping a perration techniquing and packa

ts of micro-e & delivery of ccts, Dentifrices,

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relation to Cosmcs, rheology o

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mance, Physicas creams, geessment of praffecting activity

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rfume composues of perfumeaging of perfum

mulsions, lipocosmeceuticals Hair care and

uch as aloe Ve

metic Applicatiof nail product

ks, liquids, foamosol packs.

for quality of fin

cochemical, Mels, powders, lreservative systy of preservativ

e Faculty

Osmania Univ


: 0er : 7tion : 3

t of Cosmetics

osmetics

ral & synthetic ants, antioxidavaluation of co

ition, current tes, sensory anames, legislatio

somes, niosoms. Nail preparati

era, henna, tea

ion. ts, antiperspira

m and aerosols

nished product

Microbiological ipstick, nail lactems for cosmves.

21

versity

n 00200575

Hrs.

oils, ants, lors,

trends alysis, n and

mes,

ons,

tree

ants,

s.

ts for

and cquer,

metics,


Library


Hyderabad

O

Osmania Univ

22

Unit – V Clinical Safephotoirritation,antiperspirants

Regulatory R

Books and 1. Hilda Bu2. S. Nand3. M. Paye

USA, Inc4. James S

Inc., 1995. J. Know6. J. B. Wil7. S. N. Ka8. E. G. Th9. M.S. Bal

Edited V10. R. L. Eld11. H. R. Mo12. W. C. W13. C. G. G

Plenum.14. L. Appel15. W. A. Po16. Dr. Laba17. Drugs &

versity

Chairperson

: ety Testing: , photoallergy, s, sunscreen a

Requirements

Referencestler, Klewer, Poa, A. Nanda an, A.O. Barel, Hc. 2007. Swarbrick, Jame92

wlton and S. Rekinson and R.

atju’s; Law of Dhomssen; Modsam, E. Sagar

Volumes 1,2 ander; Cosmetic oskowitz; Cosm

Waggoner; Cliniebelein, T. C. l; The Formulaoucher; Pouch

a; ‘Rheological Cosmetics Ac

BoS

; Safety and ocular irritatioand anti-aging

s: Manufacturin

s: oucher’s Perfumnd R. Khar, CoH. I. Maibach, H

es C. Boylan,

arce; Handboo J. Moore; Harrrugs; Law Pubern Cosmeticsrin, S.D. Gerhon

nd 3.Wiley‐InteIngredients, the

metic Product Tcal Safety and Cheng and V.

ation and Preper’s Perfumes, Properties of C

ct & Rules, 194

Head of th

toxicity evalun and protocoproducts.

ng and Sale of

mes, Cosmeticsmetic TechnoHandbook of C

Encyclopedia o

ok of Cosmetic ry’s Cosmetololishers (India)

s; Universal Pun, S.J.Strianse

erscience, Wileyeir Safety AsseTesting; Marce Efficacy Testin C. Yang; Cos

paration of Cos, Cosmetics anCosmetics and0 (with latest a

he Departme

ation of cosmls for the sam

f Cosmetics.

cs & Soaps, 10ology, Ed. Birla osmetic Scien

of Pharmaceut

Sciences and ogy; Longman sPvt. Ltd.

ublishing Corpoand M.M.Rieg

y India Pvt. Ltdessment; Pathoel Dekker. ng of Cosmeticsmetic and Pha

smetics, Fragrand Soaps; vol. 3d T oiletries; Maamendments)..

nt

metic productsme. Testing of

0th Ed, Academ Publications Pce and Techno

ical Technolog

TechnologyElsscience and T

oration. er, Cosmetics S

.,2008 otox.

cs; Marcel Dekarmaceutical A

ances and Flav3 Chapman anarcel Dekker

Dean of th

s; Irritation, semoisturizers, d

ic Publishers, vt. Ltd., New D

ology, Informa H

y, Vol. 6, Marc

sevier ScienceTechnical.

Science and T

kker. Applications of

vors; Micelle Pnd Hall

he Faculty

ensitization, deodorants,

NL, 2000 Delhi, 2007 Healthcare

cel Dekker

Publisher.

echnology,

Polymers;

Press.


Library


Hyderabad

Chairp

Sche

TotaHouCredInstrCou

CouTo kn

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UnitGene(moleof popolymchara

UnitEvalcharapolye

UnitTherbiodebiodecarrie

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t - I : eral Study of ecular mass, molymers, genemerizations witacteristics, cry

t - II : uation of Polacterization in electrolytes and

t - III : rapeutic Appegradable polegradable polyers (polymeric

t - IV : interactions o

apeutics, targetntion effect (EPune-modulator

t - V : ymer Drugs anapeutics

oks and RefeJ. Brandrup, E.L. H. Sperling, H. Morawetz, MC. Tanford, Ph

DRUruction

: 60 H: 3 H: 3

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mes: e knowledge o

Polymer Scimolecular weigral methods oth examples.

ystallinity.

lymers in Sosolution (therm

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lications of lymers, biodeymers in pare micelles, poly

of Polymers: Ited polymer th

PR), functional s, stimuli respo

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erences: . H. Immergur; Introduction to

Macromoleculeysical Chemist

E

Head of th

UG POLY

Hrs.Hrs.

ture .09.885.25.T

ortance of polym

f significance o

ence: Classifihtdistribution, cof preparation Methods of p

olution: Polymmodynamics oftes, cross-linke

Polymers: Pegradability anenterals and symer-coated lip

Interactions of herapeutics, paexcipients andonsive systems

Issues: Prosp

Polymer Hando Polymer Sciees in Solution (try of Macromo

ELECTIVE

he Departme

YMER TE

T

ymers use in dru

of polymers in d

cation of polymconformation a of polymers olymer modific

ers in solutionf polymer soluted polymers an

Polymers for nd biodegradurgicals, polymposomes, nano

polymers with assive targetingd biologicalresps and intracellu

pects of Polyme

dbook ;John wilence, Wiley, NY(2nd ed. ), Wileolecules, John

E

nt

CHNOLO

ug developmen

drug developm

mers, Macromand configuratilike solution bcation, Solid s

ns: Solubility otions), Viscositnd polymer co

therapeutic aability testingmer-drug conjoparticles, mic

tissues and cg of polymeric ponsemodifiersular drug delive

er Drugs and R

ley and Sons Y, 1992. ey-Interscience Wiley, NY, 196

O

Dean of th

OGY Scheme of EMax. MarksMid SemestQuizEnd SemestExam Durat

nt

ment.

molecules: strucion), Major strabulk, suspensistate properties

of polymers, mty and viscoelamplexes.

applications, of polymerugates, self-as

crospheres, etc

cells, Pharmaco drugs, enhancs, polymeric imery.

Regulatory Cha

e, NY, 1975 61.

Osmania Univ

e Faculty


: 0er : tion :

73

cture and propategies for synon and emulss of polymers

methods of poasticity of poly

biocompatible s, applicationssembled polyc.)

okinetics of poced permeatio

mmune-adjuvant

allenges in Poly

versity

23

n 00200575

Hrs.

perties thesis sions, , flow

olymer ymers,

and ns of ymeric

olymer on and ts and

ymer


Library


Hyderabad

OOsmania Univ

24

5. F6. B

M7. B8. G

P9. D10. J11. N12. P13. A

I14. A15. S16. P

versity

Chairperson

F. W. BillmeyerB. D. Ratner, AMedicine, AcadBiomedical PolG. Gebelein. T.Press, New woD. S. Soane; PJ. R. Robinson N. K. Jain; ConP. J. Tarcha; PA. F. Kydonieusnc. Academic/PlenSelf-AssemblingP. L. Felgner, L

BoS

r, Jr. TextbookA. S. Hoffman, Fdemic Press, Slymers and Po. C. Chin and Vrk. olymer Applica and V. H. Lee

ntrolled and NoPolymers for Cos; Controlled R

um Publishersg Complexes fL. W. Seymour,

Head of th

k of Polymer ScF. J. Schoen, J.San Diego, 199olymer TherapeV. C. Yang; Co

ations for Biotee: Controlled Drovel Drug Delivontrolled Drug

Release Techno

s, NY, 2001. for Gene Delive, Eds. John Wil

he Departme

cience, 3rd Ed. . E. Lemons, B96. eutics, Eds. E. osmetic and Ph

chnology; Prenrug Delivery – Fery; CBS publicDelivery; CRC

ologies: Method

ery. From Laboley & Sons: Ne

nt

John Wiley, Neiomaterials Sci

Chiellini et. al. harmaceutical A

ntice Hall Inc. Fundamentals cations. Press. ds, Theoryand A

oratory to Cliniew York, 1998.

Dean of th

ew York, 1984.ience. An Introd

, KluwerCharleApplications of

and Applicatio

Application, Vo

cal Trial. A. V.

he Faculty

. duction to Mate

es Polymers; Plen

on; Marcel Dek

l -I& II; CRC P

Kabanov,

rials in

num

kker.

ress


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ansformation p

t - II : echnology basscriptase. duction and Cohropoietin, cytoogens (recomb

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t - III : mization of ferments-raw mater

ech productsngineering in feronmental concillins, amino essing of fermeentation; produ

haracters of mi

t - IV : t biotech prodansformations echnology & G

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PHARM


de : Lectu: PY.0

ives:

basics of biote

mes:

ledge of biotec

e of Biotechnobilization of en

optical sensors

principles and in

sed pharmace

ontrol of Bioteokines; Vaccinebinant virus or control testing pyrogen test, enicity, partial

mentation procials, process a

s through fermentation – ditions of fermglycosides po

entation produucts, microbial crobes;

ducts: Substawith plant cell

GMP- Formulatticals.

E

Head of th

MACEUTI

Hrs.rs.

ure09.886.25.T

echnology in pro

hnology in dev

ology in Pharmnzymes, proteis

ndustrial applic

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echderived pres – attenuate recombinant of biotech prosterility, prote sequence ana

cesses-Ethyl Aand process va

fermentation: geometry of fmentation; Ferolyene macrolcts; Unit operastrain selection

nces produced culture; ion approaches

ELECTIVE

he Departme

CAL BIO

oduction ofdrug

velopmentof Bio

macy Enzyme ns and their

cations in the pr

recombinant

roducts: Recod virus, genetvaccinia virus)

oducts – determin identificatioalysis

Alcohol, Antibiotalidation.

Fermentation fermentation tarmentative proides, macrolid

ations and techn and preserva

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roduction ofche

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– batch, coanks, design ofoduction of imdes, anthracychniques employation methods;

culture; Transg

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aceuticals

cals

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ontinuous fermf impellers, agportant seconclines; Principyed inn downst Genotype and

genic plants an

gulatory aspect

Osmania Univ

e Faculty


: 0er : 7tion : 3

and Pharmaceenzyme electr

rugs;

ons and reve

lin, growth horms a vector of tein A, proteintion ‐viral, bactphoresis, isoele

and Pharmaceu

mentation; Rogitation systemdary metabolitles of downstream process phenotype var

nd their applica

ts of Biotechno

versity

25

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Hrs.

eutical rodes,

erse

mone, other

n G, terial ectric

utical

ole of s and tes –

stream sing of riation

ation;

ology


Library


Hyderabad

O

Osmania Univ

26

Unit - V Introduction Internet & E-mpredictive pha

Books and 1. Wisema2. Antebi E3. Higgins

Oxford.4. Stanba5. Golub E6. Bickers7. Glick. B

ASM Pr8. H. J. Re9. H. D. K10. C. Clar11. Benjam12. Bernard

Press. 13. Leo C V

Heinem14. Paul N

Inc. 15. Meran R

proteins16. William17. Sunil M

Wiley a

versity

Chairperson

: to Bio-inform

mail services, uarmaceutics, c

Referencesan A.,ed, PrincE, Fishlock D.,s 1.1., Best, D ry P.F. and WhE “The Limits ostaff GF. “EnzymBR, Pasternak ress Washingtoechm, G. Reed

Kumar, A text bok, Genetic Eng

min Lewin, Gened R Glick, John

Vining, Colin, Smann.

Chermisinoff, R

R. L. Owen, Jas, John Wiley a R Strohl, Biot

Maulik and Saliland Sons,

BoS

matics. Informause of data bahemico-pharm

s: ciples of Bio-tec, “Biotechnolog

DJ & Jones “B

hitaker, “Principof Medicine: Homes in Industry J.I., “Moleculaon.

d, Biotechnologook of Biotechngineering Fundaes V, Oxford Un E Thompson

Stuttard Butterw

Robert P Ouel

an Pen, Transgand Sons. echnologyof a D Patel, Mole

Head of th

ation theory anase in biology, maceutics, chem

chnology”, Chagy- Strategies fBiotechnology,

ples of Fermenow Science Shy and Medicinear Biotechnolog

gy. Vols 1 – 12,nology, Affiliateamentals, Karl

University Press, Methods in P

worth, Genetic

lett, Biotechnol

genic Plants: A

ntibiotics, Marcecular Biochem

he Departme

nd biology, re sequence dataminformatics,

apman & Hall. for life”, CambrPrinciples & A

ntation Technohapes our Hope, New Studiesgy-Principles a

, A. Pulher, P. Sd, East – West Kammer, Meyes. lant Molecular

and Biochemis

logy-Applicatio

production sys

cel Dekker. mistry– Therap

nt

dundancy netwa base for combioinformatics

ridge. Applications” B

ology” Pergamoe for the Cure

s in Biology” Edand Application

Stadler Eds, Wt Press Pvt. Ltder Virginia,.

Biologyand Bio

stryof Antibiotic

ns and Resear

stems for indus

peutic Applicatio

Dean of th

working, netwomparisons. App

and data min

Blackwell Scien

on Press, Oxfo Time Books, Ndwin Arnold, Lons of Recombin

Weinhelm, New d.

otechnology, C

cs Production,

rch, Technomic

trial and pharm

ons and Strateg

he Faculty

ork access, plications of ning.

ntific Pub.,

ord. New York. ondon. nant DNA”

York

RC

c Pub. Co.

maceutical

gies, John


Library


Hyderabad

Chairp

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BIOP


urse Objectimake students etion of drugs.

urse Outcomerstands the ba

t of Experim1. Comparativ2. Effect of pH3. Plasma pro4. Estimation o5. Estimation o6. Estimation o7. Estimation o

oks and RefeClinical PharmaApplied BiophaBiopharmaceutBiopharmaceutBiopharmaceutBiopharmaceutBiopharmaceutntroduction to Textbook of ApBiopharmaceutBiopharmaceutBiopharmaceutNew Delhi. Biopharmaceut

PHARMA

ruction : 60 H: 4 H: 2

de : Prac: PY.

ives: familiar with th

mes: asic mechanism

ments: ve dissolution stH / particle size

tein binding stuof pharmacokinof creatinine clof pharmacokinof pharmacokin

erences: acokinetics - coarmaceutics & tics & Pharmatics & Pharmatics - Swarbrictics & Pharmatics & Pharma Biopharmaceupplied Biophartics and Clinictics and Clinictics andPharm

tics by Swabe

Head of th

ACEUTICS

Hrs.Hrs.

ctical.09.886.22.P

the fundamenta

ms and concep

tudies on differ on dissolution udies on differenetic parametelearance. netic parametenetic paramete

oncept& applic Pharmacokinecokinetics - Mcokinetics - an

ck, Lea & Febigcokinetics. A tr

acokinetics - Putics. - G.P. -Srmaceutics andal Pharmacok

cal Pharmacokmacokinetics-AT

eic.

he Departme

S AND PH

P

al principles of

pts of absorptio

rent dosage for studies.

ent drugs. ers in urine / ser

ers for the giveners for the given

ation - Malcolmetics – LeonShilo Gibaldi , Len introduction ger book publicreatise - D. M.

P.L.Madan Shriwastav d Pharmacokininetics by John

kinetics by MiloTreatisebyD.M

nt

HARMAC

f drug absorpti

on, distribution,

rms for drugs.

rum samples.

n urinary excretn oral absorptio

mRowland&Thohargel. ea & Febiger b- RobertE.Notacation Brahmankar S

netics by Shargn and Wagnero Gibaldi. .Brahmankar a

Dean of th

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ion, distribution

, metabolism, a

tion data. on data.

omasN.Tozer, L

book publicatioary.

S B. Jasiwal

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and S.B.Jaiswa

e Faculty

Osmania Univ

TICS


: 0er : 7tion : 6

n, metabolism

and elimination

ea & Febiger b

on

al, VallbahPrak

27

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n 00200575

Hrs.

and

n.

book.

kash,


Library


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O

28

Osmania Univ


Course ObjTo understand

Course OuComprehend

List of Exper1. Preparation2. Preparation3. Preparation4. Preparation5. Preparation

Books and

Chairperson

versity

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: Mode :

de :

jectives: d the factors in

tcomes: various classes

riments: n and evaluation and evaluation and in vitro evn and evaluation and evaluatio

References

BoS

VANCED D

60 Hrs. 4 Hrs. 2 Practical PY.09.886.2

fluencing the p

s of excipients i

on of albumin mn of matrix tabvaluation of bu

on of hydrodynan of ocular film

s:

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23.P

preparation of f

involved in form

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formulation of a

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nt

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advanced drug

vanced drug de

(1 expt) tions (tablets/filexpt)

Dean of th

MS

e of ExaminMarks :

mester ::

mester :Duration :

g delivery syste

elivery systems

lms) (2 expts)

he Faculty

nation 100 20 05 75 6 Hrs.

ems.

s.


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t - II : FTING TITLES- Tables as

relationshi- Formatting- AppendiceWriting processcking: Organizaity and PrecisioTS OF DISSEduction, Reviewent, continuity,

ferences: APA (1984): PuCooper, H.M. (Dunn, F.V & O

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de : Tuto: PY.0

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research propos

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RESEARCH METHODOLOGY

Scheme of Instruction Scheme of Examination Total Duration : 30 Hrs. Max. Marks : 50 Hours/Week : 2 Hrs. Assignment : 20 Credits : 2 Attendance : 05 Instruction Mode : Tutorial Seminar : 25 Course Code : PY.09.880.X2.I Exam Duration : 1 Hr.

Course Objectives: To give exposure on how to do literature survey for the project work. To develop technical writing skills in the form of a research report. Course Outcomes: To able to organize the research in an effective fashion

Unit – I : Basics of Research: Definition, objectives, motivation, types of research and approaches; Descriptive research, conceptual, theoretical, applied and experimental. Formation of Research Problem: Research Process: To determine what type of research to be done, plan of research work; Selection of research area, prioritization of research; Literature review: importance and methods, sources; Objectives and scope ofwork, developing research plan and schedule; Scheduling constraints, steps, problems in scheduling, limitations. Experimental Modeling: Definition ofexperimental design, examples, single factor experiments, blockingand Nuisance factors, guidelines for designing experiments; General model of process: Input factors/ variables, Output parameters / variables controllable / uncontrollable variables, dependent / independent variables, experimental validity; Introduction to Risk assessment, reliability, sustainability, and uncertainty.

Unit – II : Analysis of Data: Types of data: parametric and nonparametric, descriptive and inferential data; Collection of data: normal distribution, calculation of co-relation coefficient; Data processing: analysis, error analysis, meaning, and differentmethods; analysis of variance, significance ofvariance, analysis of covariance, multiple regressions, testing linearity/nonlinearity of model, testing adequacy of model; Test to be used in data exploration and their choice; Introduction of software used in data analysis. Research Deliverables: Various Forms of Publication: T hesis, paper, research proposal; Thesis Writing: Introduction, literature review/state-of-the-art, research approach (methodology), results / findings, discussions, conclusions, scope for future work, references, appendices; Presentation: Poster, thesis, proposal, and paper. Ethical and Plagiarism issues in research: Historical perspectives, General principles on ethical consideration involving human participation, General ethical evaluation ofdrugs/ device/ diagnostics/ vaccines/ herbal remedies. Statement of specific principles for human genetics and genomic research. International Conference on Harmonization. Good clinical practices norms, Ethical principles related to animal experiments; Issues related to plagiarism, copyright laws, acknowledging the sources, format for manuscript writing, documentation, organization of reference material, bibliography, end note.

References: 1. C.R. Kothari, 2004. “Research Methodology”. 2nd Ed. New Age International (p) Limited, Publishers. 2. D. Montgomary, 2000. “Design of Experiments”. 5th Ed. Wiley Interscience. 3. K.P. Willkinsion, L. Bhandarkar, “Formulation of Hypothesis”. 3rd ed. Himalaya publishing, Mumbai. 4. Schank Fr, 2008.“Theories of Engineering Experiments”. 2nd Ed. Tata McGraw Hill. 5. J.W. Best and J.V. Kahn, 2006. “Research in Education”. 10th Ed. PHI publication.


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ENREPRENEURSHIP DEVELOPMENT

Scheme of Instruction Scheme of Examination

Total Duration : 30 Hrs. Max. Marks : 50 Hours/Week : 2 Hrs. Assignment : 20 Credits : 2 Attendance : 05 Instruction Mode : Tutorial Seminar : 25 Course Code : PY.09.880.X4.I Exam Duration : 1 Hr.

Course Objectives: To provide conceptual inputs regarding entrepreneurship management. To sensitize and motivate the students towards entrepreneurship management. To orient and impart knowledge towards identifying and implementing entrepreneurship opportunities.

Course Outcomes: To develop managementskills for entrepreneurship management

Unit - I : CONCEPTUAL FRAME WORK: Concept need and process in entrepreneurship development; Role of enterprise in national and global economy; Types ofenterprise – Merits and Demerits; Governmentpolicies and schemes for enterprise development; Institutional support in enterprise development and management; THE ENTREPRENEUR: Dynamics of Entrepreneurial Motivation; Concepts; Developing Entrepreneurial Competencies; Requirements and understanding the process of entrepreneurship development; self- awareness, interpersonal skills, creativity, assertiveness, achievement, factors affecting entrepreneur'’ role.

Unit - II : LAUNCHING AND ORGANISING AN ENTERPRISE: Environmentscanning – Information, sources, schemes of assistance, problems; Enterprise selection, marketassessment, enterprise feasibility study, SWOT Analysis; Resource mobilization - finance, technology, raw material, site and manpower; Costing and marketing management and quality control; Feedback, monitoring and evaluation; Project work – Feasibility report; Planning, resource mobilization and implementation. GROWTH STRATEGIES AND NETWORKING; Performance appraisal and assessment; Profitability and control measures, demands and challenges; Need for diversification; Future Growth – Techniques ofexpansion and diversification, vision strategies; Concept and dynamics; Methods, Joint venture, co-ordination and feasibility study;

References: 1. Akhauri, M.M.P.(1990): Entrepreneurship for Women in India, NIESBUD, New Delhi. 2. Hisrich, R.D & Brush, C.G.(1996) The Women Entrepreneurs, D.C. Health & Co., Toranto. 3. Hisrich, R.D. and Peters, M.P. (1995): Entrepreneurship – Starting, Developing and Managing a New

Enterprise, Richard D., Inwin, INC, USA. 4. Meredith, G.G. etal (1982): Practice of Entrepreneurship, ILO, Geneva. 5. Patel, V.C.(1987): Women Entrepreneurship – Developing New Entrepreneurs, Ahmedabad EDII.


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Laboratory Design, Safety and Management



Course Objectives: To expose them to existing national safety standards To acquaintwith Laboratory Design and Management

Course Outcomes: On Completion of the course the studentwill be able to perform the Experiments as per cGLPnorms.

Unit - I : Lab Design Criteria; Codes, Standards and References; Architectural Considerations, Walls, Doors, Windows, Security, Ceiling, Flooring, Cleanability, Sinks, Storage, Exit Paths, Engineering Considerations – Electrical, Plumbing, Utilities – Air, Water, Steam and Gases, Heating, Ventilation, Air Conditioning and Fume Hoods; Laboratory Furniture Design and Location; General Laboratory Safety Practices; Standard Operating Procedures (SOP’s);

Unit - II : Management of Analytical Laboratory: Organization of Laboratories based on their types, staffing, skill development and training, budgeting and financing, purchase of costly equipment, qualities of laboratory manager and management styles. Laboratory Inspections: Internal inspection, external audit, concepts, preparing for inspections and audits. Reference standards: Types, preparation, containers, labeling, storage and use. Documentation-STPs: Certificate of Analysis (COA.), LaboratoryNote Books: Typical Documents used in a GLP Laboratory including Standard Test Protocols (STP’s),

References: 1. Laboratory Design Guidelines – University of North Carolina, USA 2. Laboratory Design Hand Book 3. Designing and Planning of Laboratories (2009) 4. Laboratory Design and Construction Guidelines (2010) – Departmentof Environment, Health and Safety,

University of South Carolina, USA 5. Laboratory Safety Design Guide,(2007) – Departmentof Environment, Health and Safety, University of

California, USA 6. Laboratory Safety Guidance,(2011) – OSHA, USA

7. Safe Lab (2007) Web site at www.cpsc.gov


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Employability Skills



Course Objectives: To enhance the employability skills of learners with a special focus on presentation skills, group discussion and interview skills. To enable them to improve their soft skills necessary for workplace contexts. To equip them with effective communicative competence for a global reach.

Course Outcomes: Participate in conversations both formal and informal, attend phone calls and interviews successfully. Read different types of texts and Listen to, and understand foreign accents.

Unit - I : SPEAKING SKILLS: Conversationalskills (formaland informal contexts) - telephonic communication, attending job interviews (responding to FAQs) - taking part in GDs - making presentations. WRITING SKILLS: Job applications – cover letter – resume – applying online – writing proposals – e-Mails – letters – reports – memos – minutes – blogging – tweeting – writing recommendations and instructions – writing for publications. READING SKILLS: Vocabularybuilding – speed reading (skimming – scanning) – reading different genres of texts from newspapers to philosophical treatises – criticalreading – effective reading strategies such as reading ‘beyond the lines’, summarizing, graphic organizers and distinguishing facts from opinions. Unit - II : LISTENING/VIEWING SKILLS: Speeches of different nationalities with focus on American and British accent (TED talks, podcasts) – listening to lyrics – lectures – instructions – dialogues – news casting – talk shows – interviews (Hard talk, Devil’s Advocate) SOFT SKILLS: Motivation - persuasive skills – negotiations – time management – emotional intelligence – stress management – creative and critical thinking.

References: 1. Barker, A. Improve Your Communication Skills. New Delhi: Kogan Page India Pvt. Ltd., 2006. 2. Craven, Miles. Listening Extra – A resource book of multi-level skills activities.Cambridge University

Press, 2004. 3. Gammidge, Mick. Speaking Extra - A resource book of multi-level skills activities. Cambridge

University Press, 2004. 4. Hartley, Peter. Group Communication. London: Routledge, 2004. 5. John Seely. The Oxford Guide to Writing and Speaking. New Delhi: Oxford University Press, 2004. 6. Naterop Jean & Rod Revell. Telephoning in English. Cambridge University Press,1987. 7. Ramesh, Gopalswamy and Mahadevan Ramesh. The ACE of Soft Skills. New Delhi: Pearson, 2010.

Web Sources: 1. www.humanresources.about.com 2. www.careerride.com


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