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Heritage Frbm SaratogaO F all they faced that day at Saratoga, strive to attain the skill that groups shots in a'J Burgoyne's Redcoatsremembered longest the smaller and smaller circle. At their matches, you'llwithering accuracy of Morgan's Virginia riflemen. see a predominant use of Bausch & Lomb products.So it was at the Cowpens. Later, at New Orleans,.' Ray-Ban Shooting Glasses, the safe, scientific

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2 SCIENCE-ADVERTISEMENTS VOL. 95, No. 2468

Accelerated IntroductoryWar - Time a a| Organic ChemistryCourse

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Designed for students requiring preparation in organic chemistry before going onwith such studies as medicine, dentistry, pharmacy, home economics or agriculture, thisnew text establishes a link between general chemistry and the more advanced and spe-cialized courses which follow.

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The size of the book makes it particularly appropriate for the accellerated war-timecourse. Sufficient material is presented to allow the instructor a liberal choice of topicsand to give the student a text which will subsequently serve as a reference book. Sum-maries, review questions and especially prepared charts are included.

82 Illustrations. 482 Pages. $3.00 (1942)

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The

Foundations of ScienceBy H. POINCARE

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2 SCIENCE-ADVERTISEMENTS VOL. 95, NO. 2468

SCIENCE-ADVERTISEMENTS

VITAMIN-FREE CASEINSMACO

IN VITAMIN EXPERIMENTATION the type of dietary pro-

tein employed may well be the most important factor.When Vitamin-Free Casein SMACO is the protein in thedeficiency diet, uniform and consistent depletion of testanimals occurs well within the required time interval speci-fied by the U.S.P. or other standard test methods. Recentwork suggests the suitability of Vitamin-Free CaseinSMACO for vitamin K1 and biotin2 assay and experimentalprocedures in chicks.

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Write for the booklet "Spe- 1. ANSBACHER, S.: Proc. Soc. Exp. Biol. & Med., 46:421:1941.cial Productsfor Nutritional 2. ANSBACHER, S. and LANDY, M.: Biotin and Scaly Dermatosis of the Chick. Proc.Research" for additional in- Soc. Exp.Biol & ed., 48:3:1941.formation on Vitamin-FreeCasein SMACO, prepareddiets for U.S.P. assays, crys- RESEARCH LABORATORIEStalline vitamins and other Mbiochemicals of nutritional S. M. A. Corporationinterest. CHAGRIN FALLS,, OHIO

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SCIENCE-ADVERTISEMENTS

"TO PROVIDE FOR THE COMMON DEFENSE, TO PROMOTE THE GENERAL WELFARE"

Throats to speak our nation's pieceTHERE'S A BLOOD-TINGLING ANSWER to the challenge

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APRILJ 17, 1942 5

6SCIENCE-ADVERTISEMENTS

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6 SCIENCE-ADVERTISEMENTS Voi, 95, NO. 2468

SCIENCE

VOL. 95 FRIDAY, A-PL 17, 1942 No. 2468

Virus Infection of the Mammalian Fetus: DR. ERNESTW.GOODPASTuRE ...................................

Science and War: DR. PETER L. KAPITSA ... 396

Obituary:Frank Smith, 1857-1942: PROFESSOR PAUL S.

WELCH.Deathsand Memorials ........................................... 398

Scientific Events:Chemical Warfare Course; Memphis Meeting ofthe American Chemical Society; Scientific Meetingsat Salt Lake City; Elections to Fellowship of theRoyal Society; Medal Day at the Franklin Institute 400

Scientific Notes and News ................... ........................ 403

Discussion:Cytochrome B2: PROFESSOR T. R. HOGNESS andOTHERS. Width and Origin of Bacterial Flagella:PROFESSOR GEORGES KNAYSI. Fluorochemistry:JACK DE MENT. Sino-American Scientific Friend-

ship: DR.MoRRisSHAFFER .......................................................... 406

Quotations:The Work of the Rockefeller Foundation in 1941 407

Scientific Books:.Trends in Physics Teaching: PROFESSOR J. C. HUB-

BARD .....4....... ..................

Special Articles:Quantitative Analysis of Sulfonamide Bacterio-stasis: DR. HARRY M. ROSE and CHARLES L. Fox,JR. Relative Efficiency of Strains of RhizobiumTrifolii as Influenced by Soil Fertility: DR. JAMESL. ROBERTS and DR. FRANK R. OLSON. The Effectof Artificial Changes in the Brain on Maze-learningin the White Rat: PROFESSOR C. J. WARDEN and

OTHERS ...............................................412

Scientific Apparatus and Laboratory Methods:A Petri Dish Holder for Mechanical Stages: PRo-FESSOR WILLIAM H. WESTON. The Use of DriedPlasma for the Coagulase Test: EDWARD J. FOLEY 415

Science News 8

SCIENCE: A Weekly Journal devoted to the Advance-ment of Science, edited by J. MCKEEN CATMLL and pub-lished every Friday by

THE SCIENCE PRESSLancaster, Pa. Garrison, N. Y.

Annual Subscription, $6.00 Single Copies, 15 Cts.SCIENCE is the official organ of the American Associa-

tion for the Advancement of Science. Information regard-ing membership in the Association may be secured fromthe office of the permanent secretary In the SmithsonianInstitution Building, Washington, D. C.

VIRUS INFECTION OF THE MAMMALIAN FETUS1By Dr. ERNEST W. GOODPASTURE

DEPARTMENT OF PATHOLOGY, VANDERBILT UNIVERSITY MEDICAL SCHOOL, NASHVILLE, TENN.

EXPERIENCE extending over a number of years withexperimental inoculation of embryos of incubatinghen-eggs has demonstrated a high degree of suscepti-bility of the developing avian cells and tissues to anumber of infectious agents including viruses, bac-teria, spirochaetes, fungi and protozoa. It is evidentthat this avian host in its embryonic stage is muchmore susceptible to several infections than are adultchickens and perhaps more so than the natural hostof particular agents concerned.

Indicative of a greater susceptibility of chick em-1 A lecture delivered before Section B-17 of the Sym-

posia of the fiftieth anniversary of the University ofChicago, September 26, 1941.

bryos as compared with the adult hen or with a mam-malian host is the wide dissemination of focal areasof infection within the body of the embryo inoculatedin the chorioallantoic membrane with, for example,the viruses of vaccinia or herpes simplex, neither ofwhich causes more than a mild local lesion in chickens,and ordinarily no conspicuous if any disseminatedlesions in mammals. It is not to be inferred, how-ever, that avian embryonic cells and tissues can beinfected by any virus or other agent, for they possesstoward some agents a complete refractiveness that isof the nature of natural immunity.

Experimenters who have utilized mammalian em-

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