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Second-Cycle Degree Course in REPRODUCTIVE BIOTECHNOLOGIES A.Y. 2018-2019

Second-Cycle Degree Course in REPRODUCTIVE …€¦ · (from Linkedin) 6/33 18/33 LONDON (UK) ++ CAMBRIDGE (UK) ++ WIESBADEN (Germany) WARSAW (Poland) 9/33 Second-cycle Degree Course

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Page 1: Second-Cycle Degree Course in REPRODUCTIVE …€¦ · (from Linkedin) 6/33 18/33 LONDON (UK) ++ CAMBRIDGE (UK) ++ WIESBADEN (Germany) WARSAW (Poland) 9/33 Second-cycle Degree Course

Second-Cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

A.Y. 2018-2019

Page 2: Second-Cycle Degree Course in REPRODUCTIVE …€¦ · (from Linkedin) 6/33 18/33 LONDON (UK) ++ CAMBRIDGE (UK) ++ WIESBADEN (Germany) WARSAW (Poland) 9/33 Second-cycle Degree Course

1.

EDUCATIONAL AND

PROFESSIONAL GOALS

2. TEACHINGS’

BALANCE

3. RESEARCH AREAS

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Cell biology and physiology of gametogenesis, fertilization and embryo development

Gamete handling

Embryo culture

Andrology

Micromanipulation techniques

(IVM, IVF, ICSI)Advances in cryobiology

Epigenetic, toxicology, angiogenesis concepts related to reproduction

Pre-implantation genetic diagnosis

Ethical and legal controversies surrounding assisted

reproduction in humans

Students will receive training in:

1. EDUCATIONAL GOALS

The Course will provide the

fundamental theoretical

and practical knowledge

necessary to understand

and perform up-to-date

techniques in the areas of

Assisted Reproduction

Technology (ART).

The MSc is a laboratory-based

science degree and is taught by

world-leading academics and

leading reproductive medicine

specialists from professional world.

Page 4: Second-Cycle Degree Course in REPRODUCTIVE …€¦ · (from Linkedin) 6/33 18/33 LONDON (UK) ++ CAMBRIDGE (UK) ++ WIESBADEN (Germany) WARSAW (Poland) 9/33 Second-cycle Degree Course

MAIN CAREER OPPORTUNITIES FOR GRADUATES IN RP

ACADEMIA

II LEVEL MASTER

PhD

COURSE

EMPLOYMENT

CLINICS OF ASSISTED

REPRODUCTIVE TECHNOLOGY

LIVESTOCK CENTERS

DIAGNOSTIC/RESEARCH CENTERS

COMMERCIALAREA

UNITE

Cellular and Molecular

Biotechnology

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

The Reproductive Biotechnologies MSc allows graduates to pursue

a career in assisted reproduction and/or research in the reproductive

sciences, both in human and animal field.

1. PROFESSIONAL GOALS

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EMBRYOLOGISTS or BIOTECHNOLOGISTS (73%)

RESEARCHERS or PhD STUDENTS (27%)

LONDON (UK)

LEUVEN (Holland)

MURCIA (Spain)

CACERES (Spain)

PHILADELPHIA (USA)

WIEN (AUSTRIA)

TERAMO ++

CHIETI

LONDON WIESBADEN

WARSAW

CAMBRIDGE

MILANO +++

BOLOGNA

MODENA

REGGIO EMILIA

ASCOLI PICENO

TERAMO ++

L’AQUILA

PESCARA

ROMA++

NAPOLI

SALERNO

CASERTA

BARI

POTENZA

A sample of 33 graduates in RP from UniTE

(from Linkedin)

18/336/33

LONDON (UK) ++

CAMBRIDGE (UK) ++

WIESBADEN (Germany)

WARSAW (Poland)

9/33

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

EDUCATIONAL RESULTS

Page 6: Second-Cycle Degree Course in REPRODUCTIVE …€¦ · (from Linkedin) 6/33 18/33 LONDON (UK) ++ CAMBRIDGE (UK) ++ WIESBADEN (Germany) WARSAW (Poland) 9/33 Second-cycle Degree Course

I YEAR

Structure and Function of the Reproductive System

Biology of gametes, IVM and IVF Techniques

Andrology I

Molecular Markers in Reproduction

Embryology

Cryobiology

Scientific Communication, part I

BASIC TEACHING SUBJECTS

(+++ animal samples)

II YEAR

Genetics of Human Reproduction

Diagnostic Histology Applied to Cells and Tissues of the RS

Andrology II

ICSI Procedure and Advanced Techniques in PMA

Legislation and Bioethics in Medicine of Reproduction

Scientific Communication, part II

PROFESSIONALISING TEACHING SUBJECTS

(+++ human samples)

2. TEACHINGS’ BALANCE

ELECTIVE COURSES - Angiogenesis and reproduction

- Developmental and reproductive toxicology

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

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Career Days(stakeholders)

Preliminary meetings

(all teachers)

Info requestedto each teacher

Name:………..

E-mail:…………

Skype:………..

Phone:………….

Office:………….

Course Title:

Objectives:

Interactions:

Research Interest:

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

2. TEACHINGS’

BALANCE

Page 8: Second-Cycle Degree Course in REPRODUCTIVE …€¦ · (from Linkedin) 6/33 18/33 LONDON (UK) ++ CAMBRIDGE (UK) ++ WIESBADEN (Germany) WARSAW (Poland) 9/33 Second-cycle Degree Course

EXAMPLES

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BASIC KNOWLEDGE in:

Cytology

Cell Physiology and Cell Culture

Biochemistry and Molecular Biology

Applied and Medical Genetics

English language

I YEAR

II YEAR

Elective courses

ENTRY REQUIREMENTS

Bachelor or Master degree in an appropriate

biological-, biomedical- or veterinary- science subject,

medicine or healthcare science (Biotechnologies, Life

Sciences, Livestock science, Nursing, Pharmacy,

Medicine, Veterinary Medicine,…)

ENTRANCE TEST

(not mandatory)

+

REMEDIAL

COURSES

(Nov-Dec)

The course is delivered

using: lectures,

seminars, team based

learning exercises,

flipped classrooms,

presentations and

problem-based-

learning sessions or

case studies, and self-

directed learning.

Theoretical training is

complemented by a

consistent number of

hands-on laboratory-

based practical

sessions.

The course content is

enhanced by extensive

online resources and

the provision of all

lessons through the E-

learning platform.

Jan-June

Jan-May

Nov

Graduation

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3. RESEARCH AREAS

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http://old.iss.it/rpma/index.php?lang=1&anno=2019&tipo=6

WHERE TO FIND USEFUL INFORMATION: REGISTRO NAZIONALE PMA (in italian)

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https://www.facebook.com/Reproductive-Biotechnologies-

University-of-Teramo

http://www.unite.it/UniTE/Didattica/Corsi_di_laurea_2018_2019/

Programme Director:

Alessia Colosimo [email protected]

Orientation

Educational Manager:

Natalia Izzi [email protected]

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

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Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

FIRST YEAR

STRUCTURE AND FUNCTION OF THE REPRODUCTIVE SYSTEM 11 Cfu

BIOLOGY OF GAMETES, IVM AND IVF TECHNIQUES 10

ANDROLOGY I 6

MOLECULAR MARKERS IN REPRODUCTION 12

EMBRYOLOGY 6

CRYOBIOLOGY 11

SCIENTIFIC COMMUNICATION, PART I 3

Page 14: Second-Cycle Degree Course in REPRODUCTIVE …€¦ · (from Linkedin) 6/33 18/33 LONDON (UK) ++ CAMBRIDGE (UK) ++ WIESBADEN (Germany) WARSAW (Poland) 9/33 Second-cycle Degree Course

Name: Valentina Russo

E-mail: [email protected]

Skype: russoval

Phone: 0861 266930

Office: 3rd floor – Faculty of Bioscience

Course Title: STRUCTURE AND FUNCTION OF THE REPRODUCTIVE SYSTEM (I year)

Objectives:

to provide an in-depth knowledge on the neuroendocrine mechanisms and on the

existing relations between the structure and function of the female reproductive system

in domestic animals and humans

Research Interest:

AMNIOTIC STEM CELL BIOLOGY, REGENERATIVE MEDICINE, TISSUE ENGINEERING

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

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Name: Barbara Barboni

E-mail: [email protected]

Skype: barbara barboni

Phone: 0861 266878

Office: 3rd floor – Faculty of Bioscience

Course Title: BIOLOGY OF GAMETES, IVM AND IVF TECHNIQUES (I year):

- BIOLOGY OF GAMETES

Objectives:

To provide deepened knowledge and methods on mechanisms &

signalling pathways involved in mammalian gametes differentiation,

growth, maturation and activation.

Research Interest:

FOLLICULOGENESIS IN VITRO, OOCYTE QUALITY, IVM INNOVATION

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

Page 16: Second-Cycle Degree Course in REPRODUCTIVE …€¦ · (from Linkedin) 6/33 18/33 LONDON (UK) ++ CAMBRIDGE (UK) ++ WIESBADEN (Germany) WARSAW (Poland) 9/33 Second-cycle Degree Course

Name: Luisa Gioia

E-mail: [email protected]

Skype: luisagioiaaq

Phone: 0861 266857

Office: 3rd floor – Faculty of Bioscience

Course Title: BIOLOGY OF GAMETES, IVM AND IVF TECHNIQUES (I year):

- TECHNIQUES OF IN VITRO MATURATION AND FERTILIZATION

Objectives:

to train students to develop theoretical and practical skills on techniques of in vitro

maturation (IVM) and in vitro fertilization (IVF) using spermatozoa and oocytes of

domestic animals

Research Interest:

REGULATION OF OOCYTE IVM; MARKERS OF OOCYTE QUALITY; MOLECULAR

MECHANISMS INVOLVED IN GAMETE INTERACTION AND IVF; MECHANISMS OF CELL

DEATH IN GAMETES AND FOLLICULAR CELLS

MII

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

Page 17: Second-Cycle Degree Course in REPRODUCTIVE …€¦ · (from Linkedin) 6/33 18/33 LONDON (UK) ++ CAMBRIDGE (UK) ++ WIESBADEN (Germany) WARSAW (Poland) 9/33 Second-cycle Degree Course

Name: Alberto Contri

E-mail: [email protected]

Phone: 0861 266995

Mobile: 3479131616

Office: Ist floor – Faculty of Veterinary Medicine

Loc. Piano d’Accio

Course Title: ANDROLOGY I (I year)

Objectives:

the course provides information about the normal structure and function of

animal sperm. The student will be trained on the basic and advanced

sperm evaluation in mammals.

Research Interest:

DETERMINANTS OF SPERM PRESERVATION IN THE BULL AND DOG; SPERM

MATURATION IN STALLION AND TOM; IMPROVEMENT OF HYGENIC AND

FUNCTIONAL QUALITY OF PRESERVED SPERM IN BULL, DOG, AND STALLION

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

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Name: Natalia Battista

E-mail: [email protected]

Skype: nataliabattista

Phone: 0861 266844

Office: 3rd Floor – Faculty of Bioscience

Course Title: MOLECULAR MARKERS IN REPRODUCTION (I year)

- TECHNIQUES FOR BIOMARKERS IN HUMAN REPRODUCTION

Objectives:

To achieve the knowledge of the main concepts concerning theoretical and

practical methodologies that enable the identification and quantification of

various

biological biomarkers of fertility.

Research Interest:

BIOCHEMISTRY OF BIOACTIVE LIPIDS INVOLVED IN

INFLAMMATORY, NEURODEGENERATIVE AND REPRODUCTIVE PROCESSES

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

Page 19: Second-Cycle Degree Course in REPRODUCTIVE …€¦ · (from Linkedin) 6/33 18/33 LONDON (UK) ++ CAMBRIDGE (UK) ++ WIESBADEN (Germany) WARSAW (Poland) 9/33 Second-cycle Degree Course

Course Title: MOLECULAR MARKERS IN REPRODUCTION (I year)

- BIOMARKERS IN HUMAN REPRODUCTION

Objectives:

to provide students with a core of skills on the biochemical nature of the different classes of compounds that act

as intra- and inter-cellular messengers in the molecular and cellular mechanisms of the reproductive processes.

Research Interest:

BIOCHEMISTRY OF BIOACTIVE AND NUTRACEUTICAL LIPIDS IN THE MOLECULAR MECHANISMS OF

PHYSIOLOGICAL PROCESSES, INCLUDING REPRODUCTIVE EVENTS AND INFLAMMATORY, NEURODEGENERATIVE

AND TUMOR PATHOLOGIES

Name: Cinzia Rapino

E-mail: [email protected]

Phone: 0861 266842

Office: 3rd Floor – Faculty of Bioscience

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

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Name: Pasqualino Loi, DVM, PhD

E-mail: [email protected]

Phone: 0861 266856

Office: 3rd floor – Faculty of Bioscience

Course Title: EMBRYOLOGY (I year)

Objectives:

To provide students with an updated view of basic embryology in mammals and other model

organisms (Fish, Amphybians, Birds, Insects). To get students acquainted with the classical

micromanipulation techniques used for assisted reproduction in animals and humans as well as

in experimental embryology.

Research Interest:

NUCLEAR REPROGRAMMING-REMODELLING, SOMATIC CELL NUCLEAR TRANSFER,

MONOPARENTAL EMBRYOS, EMBRYO-MATERNAL INTERACTION, BIODIVERSITY

PRESERVATION

In vitro nuclear remodelling Loi, et al.

Nuclear Transfer, Loi, et al.,

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

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Nuclear Transfer, Loi, et al.,

Course Title: CRYOBIOLOGY (I year)

- MOLECULAR INTERACTIONS AMONG GAMETES AND ENVIRONMENT

Objectives:

The course aims at providing an updated description of the molecular interactions

and mechanisms responsible for a functional modulation of gametes and embryo

after cryopreservation. A particular focus will be on the protein/protein and

protein/membrane interactions, ROS production, and epigenetic modifications.

Research interests:

MEMBRANE BIOLOGY AND FUNCTIONAL INTERACTIONS AMONG BIOACTIVE LIPIDS

AND MEMBRANE ENZYMES AND RECEPTORS IN CELL MODELS AND GAMETES

Name: Enrico Dainese

E-mail: [email protected]

Skype: enrico_dainese

Phone: 0861/266876

Office: 3rdFloor–Faculty of Bioscience

Fro

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Da

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Bio

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20

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) 4

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, 4

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–4

72

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

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Name: Nicola Bernabò

E-mail: [email protected]

Skype: nicolabernabo

Phone: 0861 266836

Office: 3rd Floor – Faculty of Bioscience

Course Title: CRYOBIOLOGY (I Year)

- CRYOPRESERVATION TECHNIQUES OF GAMETES

Objectives:

To give students an updated information about the criopreservation

techniques of gametes and embryos.

Research Interest:

SIGNAL TRANSDUCTION OF SPERMATOZOA; CAPACITATION; IVF; SYSTEMS AND

COMPUTATIONAL BIOLOGY Fro

m:

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et

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Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

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Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

SECOND YEAR

GENETICS OF HUMAN REPRODUCTION 10 Cfu

DIAGNOSTIC HISTOLOGY APPLIED TO CELLS AND TISSUES OF THE RS 5

ANDROLOGY II 6

ICSI PROCEDURE AND ADVANCED TECHNIQUES IN PMA 6

LEGISLATION AND BIOETHICS IN MEDICINE OF REPRODUCTION 6

SCIENTIFIC COMMUNICATION, PART II 3

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Name: Alessia Colosimo

E-mail: [email protected]

Phone: 0861 266840

Office: 3rd floor – Faculty of Bioscience

Course Title: GENETICS OF HUMAN REPRODUCTION (II year)

Objectives:

the course provides information on infertility-related diseases due to genetic causes.

The student will be trained on the basic and advanced molecular tests, PGD/PGS tests and

counseling protocols for infertile couples.

Research Interest:

AMNIOTIC STEM CELLS IN REGENERATIVE MEDICINE; ADVANCED MOLECULAR AND

CYTOGENETICAL TECHNIQUES IN DIAGNOSIS OF INFERTILITY (Un. CHIETI); EPIGENETIC AND

NUTTIGENETIC FACTORS INVOLVED IN MALE INFERTILITY (Un. CHIETI)

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

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Name: Leonardo Della Salda

E-mail: [email protected]

Phone: 0861 266866

Office: OVUD–Faculty of Veterinary Medicine

Course Title: DIAGNOSTIC HISTOLOGY APPLIED TO CELLS AND TISSUES OF THE

REPRODUCTIVE SYSTEM (II Year)

Objectives:

To provide understanding of the pathogenesis and morphological aspects of cell

injury/death, cellular growth and neoplasia of the reproductive system in domestic

animals and humans

Research Interest:

SIGNAL TRANSDUCTION PATHWAYS IN REPRODUCTIVE NEOPLASIA,

CANCER /MESENCHIMAL INTERACTION

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

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Name: Arcangelo Barbonetti (University of L’Aquila)

E-mail: [email protected]

Phone: 347 6413629

Office: University of L’Aquila

Course Title: ANDROLOGY II (II Year)

Objectives:

To reproduce validated protocols commonly applied to laboratory diagnosis of male

infertility, in sperm processing for assisted fertilization procedures and in basic/clinical

research in the field of reproductive medicine.

Research Interest:

HUMAN SPERM BIOLOGY; SPERM OXIDATIVE DAMAGE; MALE INFERTILITY;

REPRODUCTION ENDOCRINOLOGY; HYPOGONADISM

ROS

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

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Name: Ilaria Listorti

E-mail: [email protected]

Phone: 06 8550385

Office: Alma Res - Rome

Course Title: ICSI PROCEDURE AND ADVANCED TECHNIQUES IN MEDICALLY-

ASSISTED PROCREATION (II year)

Objectives:

To show the importance of biological knowledge when performing diagnosis,

prevention and treatment of human infertility

Research Interest:

IVF; EMBRYO CULTURE; OXIDATIVE STRESS AND INFERTILITY

ICSI

Embryo culture

Blastocyst biopsy

Preimplantation Genetic Test

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

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Course Title: SCIENTIFIC COMMUNICATION (I and II year)

Objectives:

To give knowledge and understanding of cultural, social and political issues around

science communication; to learn how to use scientific communication through printed

paper and online (internet) news (I year) and how to use scientific communication on

television and radio (II year).

Research Interest:

MEDICAL SPEAKING AND WRITING ABILITY, INFORMATION RETRIEVAL, SCIENTIFIC

READING AND WRITING, LISTENING AND OBSERVING, INFORMATION REPRESENTATION

AND KNOWLEDGE PRESENTATION, SOCIAL NETWORKS IN MEDICAL PRACTICE.

Name: Massimo Cecaro

E-mail: [email protected]

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

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Course Title: LEGISLATION AND BIOETHICS IN MEDICINE OF REPRODUCTION

(II Year)

Objectives:

To provide a complete and updated description of legislation and bioethics in

medicine of reproduction, comparing the Italian legislative body to the ones of

different European countries.

Research Interest:

WOMEN'S RIGHTS IN ITALY, WITH REGARD TO ACCESS TO WORK

Name: Angela Musumeci

E-mail: [email protected]

Phone: 0861 266629

Office: 3rd floor – Faculty of Law

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

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Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

ELECTIVE COURSES

ANGIOGENESIS AND REPRODUCTION 3 Cfu

DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY 5

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Name: Alessandra Martelli

E-mail: [email protected]

Phone: 0861 266889

Office: 3rd floor – Faculty of Bioscience

Course: ANGIOGENESIS AND REPRODUCTION (Elective course)

Objectives:

To provide an in-depth understanding ovarian chronological angiogenesis modulation during

ovarian folliculogenesis: from the primordial follicles to the antral periovulatory phases

Research Interest:

MORPHOLOGICAL ASPECTS AND MOLECULAR AND MORPHO-FUNTIONAL MODIFICATIONS

INVOLVED IN THE RECOGNITION OF THE MALE AND FEMALE GAMETES AND DURING FOLLICULAR

GROWTH

Nuclear Transfer, Loi, et al.,

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES

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Name: Monia Perugini

E-mail: [email protected]

Skype: monia.perugini

Phone: 0861 266988

Office: 3rd floor – Faculty of Bioscience

Course Title: DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY (Elective course)

Objectives:

To describe the mechanisms leading to infertility or alteration during the embryo

development and to give an overview of chemicals associated to the reproductive problems

in humans and animals.

Research Interest:

TOXICOLOGICAL TESTS, EMBRYONIC ZEBRAFISH MODEL, MOLECULAR PATHWAYS,

DEVELOPMENTAL TOXICITY

Second-cycle Degree Course in

REPRODUCTIVE BIOTECHNOLOGIES