Separating a Synthetic Pain Relief Mixture

What is the mass percent of pain reliever in your mixture?

Methods of Separation

• Filtration, evaporation, crystallization, distillation, extraction

What is extraction?

Based on immiscible (liquid-liquid) substances

Use about 50 mL ethyl acetate and let sit for 5-7 minutes.

How to use separatory funnel

1.Close stop cock to ensure liquid will not spill.

2.Hold stopper when inverting the funnel to avoid having the stopper fall out when funnel is upside down.

3.Open stopcock to VENT excess pressure.

4.Repeat the shaking/venting process to ensure equilibrium distribution of the organic solute between the desired layers.

Reaction of Acid and Base

Reaction of Acid and Base

+ NaOH salt and water

+ H2OCOONa

Salt

Reaction of Acid and Base

+ NaOH salt and water

+ H2O

Salt

NaO

Reaction of Acid and Base