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Sex-linked Traits. Sex determination. Sex chromosomes – determines the sex of an individual Y X Males have X and Y Two kinds of gametes Female have two X’s Only one type of gamete. Which parents determines the sex of the offspring?. XY male. X. Y. XX Female. X. X. - PowerPoint PPT Presentation
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Sex-linked Traits
Sex determinationSex chromosomes – determines
the sex of an individualY X
Males have X and YTwo kinds of gametes
Female have two X’sOnly one type of gamete
Which parents determines the sex of the offspring?
XYmale
X Y
XXFemale
X
X
It is the male that determines the sex of the offspring.
Sex Linked TraitsTraits controlled by genes located on
sex chromosomes (X or Y)Most are X-linked
The X chromosome is larger and has more genes
A Y has very few genesShow inheritance pattern that differs
for autosomal traits.
X-linked Inheritance
Males only have one copy of the X chromosome (hemizygous), plus a Y
Female have two X chromosomes, and may be homozygous or heterozygous for a trait
X-linked genes are never passed from father to son. The Y chromosome is the only sex chromosome that passes from father to son.
Females with one copy of the normal gene and one copy of the mutated gene are called carriers. They don’t show the trait.
Males are never carriers – if they have a mutated gene on the X chromosome, it will be expressed
X-linked disordersRecessive
Red-green color blindness
HemophiliaDuchenne muscular
dystrophy Ichthyosis
DominantHypertrichosis
Red-green color blindnessCan not distinguish red from
green.Normal red-green Red-green colorblind
What a red-green colorblind person would see
Normal Red-green colorblind
X Chromosome InactivationWhile females have two X
chromosomes, only one is active.The other is turned off.
This is random, in some cells the maternal X is turned off and in others the paternal X is turned off.
All descents of that cell will have same X turned off
It is condensed and known as a Barr Body.
Hemophilia
Non-carrier Mother + Father With Hemophilia
Carrier Mother + Non-hemophiliac Father
Carrier Mother + Father With Hemophilia