SHOOT FOR THE MOON! - DE Breast Cancerdebreastcancer.org/pdf/Dr._Krein_DBCC_StartUpHealth_FINAL_.pdf · The Healthcare Transformer Mindset™ and The Healthcare Transformer Mindset™are

SHOOT FOR THE MOON!

Howard Krein MD, PhD

Head and Neck Cancer SurgeryFacial Plastics and Reconstructive Surgery

Microvascular Surgery

Senior Director of Health Policy and InnovationSidney Kimmel Cancer Center

StartUp HealthChief Medical Officer

Son, Husband, Brother, Uncle, Friend

CONFIDENTIAL INFORMATION. NOT FOR DISTRIBUTION.

“MOONSHOT MINDSET” Embraces the idea that audacious goals

are the best way to bring revolutionary

changes to health


CALICO

MD ANDERSON CANCER CENTER MOONSHOT

PROGRAM

WHITE HOUSE PRECISION MEDICINE INITIATIVE

FEDERAL MOONSHOT PROGRAM

BIDEN FOUNDATION’S CANCER INITIATIVE

STARTUP HEALTH


It’s inevitable that audacious plans

sometimes fall short of their stated

missions or don’t happen as

fast as we’d like.


In order to achieve the next great

leap, we need to dream big, keep

innovation open and transparent,

collaborate more, and embrace the

moonshot mindset.


The only way to make breakthroughs

is by working passionately and

around-the-clock to turn far-fetched

visions into reality.


“We always overestimate what we can

do in two years, and we underestimate

what we can do in ten years.”- Mark Zuckerberg, Building Global Community, Feb 17, 2017


“Moonshots are carrying the hopes and dreams

of millions of people who want us to succeed,

make a difference in their lives and their

families. Not someday, but now.”- Joseph R. Biden

ORGANIZING AND SUPPORTING A GLOBAL

ARMY OF HEALTH TRANSFORMERS

Howard Krein MD, PhDChief Medical Officer

@drkrein @startuphealth

to improve the health and wellbeing of everyone in the world

11JOIN THE HEALTH TRANSFORMER

MOVEMENT™ & © 2017 StartUp Health Holdings, Inc. All rights reserved.

MISSION

ORGANIZING AND SUPPORTINGA GLOBAL ARMY OF

HEALTH TRANSFORMERS™


MOVEMENT

IMPORTANCE

TO ACHIEVE 10 HEALTH MOONSHOTS

1 Access to Care

2 Cost to Zero

3 Cure Disease

4 End Cancer

5 Women’s Health

6 Children’s Health

7 Nutrition & Fitness

8 Brain Health

9 Mental Health & Wellbeing

10 Longevity

™ & © 2017 StartUp Health Holdings, Inc. All rights reserved.


MOVEMENT

100YEARS

25 YEARS

ACHIEVE 100 YEARS OF PROGRESS IN 25 YEARS

WITH A 25 YEAR MISSIONTo Improve the Health and Wellbeing of Everyone in the World


2011LAUNCH

2017

14

400+ Entrepreneurs from 17 Countries and 5 Continents

A GLOBAL ARMY ON A SINGLE MISSION

NEW YORK

™ & © 2017 StartUp Health Holdings, Inc. All rights reserved. 14

JOIN THE HEALTH TRANSFORMER

MOVEMENT

Tracking 7,500+ Startups Globally Totaling $25B in Funding



ARMY RAPIDLY GROWING AT INCREASING RATE

023

5386

120

180

300

2011 2012 2013 2014 2015 2016 2017

0 to 194 in 5 Years Selected from 4,500+ Applications



MOVEMENT


MOVEMENT


HEALTH TRANSFORMERS™

HEALTH TRANSFORMERS

LONG-TERM COMMITMENT

SUPPORTIVE RELATIONSHIPS

QUARTERLY & WEEKLY RHYTHYM

CONFIDENTLY AMBITIOUS

SELF-AWARE

HEALTHY HABITS

VALUE CREATOR

BATTERIES INCLUDED

1

2

3

4

5

6

7

8

BUILD MOONSHOT COMPANIES

MOONSHOT STORY & MASTER PLAN

BACKABLE ENTREPRENEURS & TEAM

DIFFERENTIATED BRAND & VALUE PROP

CONTINUALLY INCREASING TRACTION

PROPRIETARY TECHNOLOGY

SCALABLE BUSINESS MODEL

VALUABLE PARTNERSHIPS

CAPITAL TO EXECUTE

1

2

3

4

5

6

7

8

CHOOSE MOONSHOT PARTNERS

CEO URGENCY

COMMITTEDTEAM

MODEL FOR OTHERS

START UP MOMENTUM

CAPABILITYALIGNMENT

VALUE ALIGNMENT

CHAMPION OF ENTREPRENEURS

COMMITTED CAPITAL

1

2

3

4

5

6

7

8

Committed to Mastering the 24 Moonshot Mindsets™


MOVEMENT


TO CHANGE YOUR MINDSET,CHANGE YOUR WORDS

™ & © 2017 StartUp Health, LLC. All rights reserved. The Healthcare Transformer Mindset™ and The Healthcare Transformer Mindset™ are integral concepts of StartUp Health and may not be reproduced in any form, or by any means whatsoever, without written permission from StartUp Health. Made in the United States. StartUp Health and Healthcare Transformer is a registered trademark of StartUp Health, LLC.



HEALTH MOONSHOTSnoun

“Moonshots live in the gray area between audacioustechnology and pure science fiction. The combinationof a huge problem, a radical solution to that problem,and the breakthrough technology that just might makethat solution possible, is the essence of a moonshot.”

- Google X


CURE DISEASE MOONSHOTSCure disease using data, tech & personalized medicine

Melissa is on a mission to deconstruct chronic respiratory disease for the millions globally that suffer from Asthma & COPD

Melissa Manice, PhD


MOVEMENT

Co-Founder & CEOCohero Health, Inc.


Jasvir is on a mission to democratize personalized cancer therapeutics for millions of cancer patients that have exhausted current standards of care

CANCER MOONSHOTSEnd cancer as we know it

Jasvir Zonobi


MOVEMENT

Co-Founder & CEOKuveda, Inc.


WOMEN’S HEALTH MOONSHOTSPrioritize women's health

Anish is on a mission to ensure that the 200M+ expecting mothers throughout the world experience safe & healthy pregnancies

Anish Sebastian


MOVEMENT

Co-Founder & CEOBabyscripts, Inc.


Hesky is on a mission to deliver crucial health services to 50M students annually through public schools that serve as the front line of pediatric care

CHILDREN’S HEALTH MOONSHOTSEnsure every child has access to quality care

Hesky Kutscher


MOVEMENT

Founder & CEOCaredox, Inc.


NUTRITION & FITNESS MOONSHOTSReclaim food as our ultimate medicine

Victor is on a mission to capture the world's food knowledge and provide fast & accurate real-time nutrition analysis

Victor Penev


MOVEMENT

Founder & CEOEdamam, Inc.


BRAIN HEALTH MOONSHOTUnlock the mysteries of the brain to improve health

Adam is on a mission to diagnose millions that suffer from concussions early enough to avoid life long complications

Adam Simon


MOVEMENT

Co-Founder & CEOCerora, Inc.


LONGEVITY MOONSHOTSAdd 50+ healthy years to every human life

Craig is on a mission to extend and improve healthy human life by making data from over 10,000 genomes available to researchers

Craig Venter


MOVEMENT

Co-Founder & Executive Chairman

Human Longevity, Inc.


Lynda is on a mission to ensure that no patient is alone - every patient on the planet is connected to the support they need.

Lynda Brown-GanzertCo-Founder & CEO

Curatio

MENTAL HEALTH & WELLBEING MOONSHOTDestigmatize mental health & connect mind, body and spirit


MOVEMENT

ACCESS TO CARE MOONSHOTDeliver care to everyone, regardless of location or income

Aschkan Abdul Malek is on a mission to provide patients in developing countries with access to incredible quality diagnostic care from all over the world.


MOVEMENT

Aschkan Abdul MalekCo-Founder & CEO

Confidential Information. ™ & © 2016 StartUp Health Holdings, Inc. All rights reserved.28


Eran is on a mission to optimize physician and patient communication

Eran KabakovCo-Founder & CEO

DocolaJOIN THE HEALTH TRANSFORMER

MOVEMENT

COST TO ZERO MOONSHOTSRadically reduce the cost of care by a factor of a million

THE WORLD’S LARGEST DIGITAL HEALTH PORTFOLIO

A COLLABORATORY OF LEADING PARTNERS

CONFIDENTIAL INFORMATION. NOT FOR DISTRIBUTION.30JOIN THE HEALTH TRANSFORMER

MOVEMENT

Jerry Levin Nick Turkal, MD Mark Cuban Brad Feld Steve Case Esther Dyson Wayne Kimmel

Fmr. Chair & CEO, Time

Warner

CEO, Aurora Health Care Owner, Dallas Mavericks Managing Dir., Foundry Group Founder & Fmr. Chair, AOL Founder, Way to Wallville Mng. Partner, SeventySix

Capital

Ira Brind Roger Ehrenberg Jason Finger Richard Forman Doug Galen Linda Holliday Jon Kaplan

Partner, Pulse Equity Partners Managing Partner, IA Ventures Founder & Fmr CEO, Seamless Co-Founder, Vitals.com CEO, RippleWorks CEO, CITIA Fmr VP, Global Sales, Google

Marty Lautman Andrew Litt, MD Jeff Markowitz Don Middleberg Jon Miller Trevor Price Connie Williams

Mng. Partner, Marketing

Channels

Fmr. CMO, Dell Healthcare Partner, Greylock CEO, Middleberg Consulting Fmr. CEO, AOL CEO, Oxeon Partners Fmr. PA State Senator

Investors with the Transformational Mindset



MOVEMENT

COLORADOFINLAND

HealthcareFinland

Regional Affiliate Network Partners

A COLLABORATORY OF LEADING PARTNERS



MOVEMENT

A COLLABORATORY OF LEADING PARTNERS Custom Innovation Portfolio Partners



MOVEMENT

A COLLABORATORY OF LEADING PARTNERS Network Partners and Sponsors

Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data on seed, venture, corporate venture and private equity funding only through September 30, 2016. © 2016 StartUp Health LLC

34

Academy Companies Acquired

10

by

by

by

by

by

Female Founders

30%

by

Serial Entrepreneurs

34%

MDs and PhDs

43%

Total Raised by All Companies*

$617M

*$300M raised by HLI

by

by

by

0

15

30

45

60

75

90

105

120

135

150

165

180

'11 '12 '13 '14 '15 '16

192StartUp Health Companies

34

by

Outside the US

15%

HEALTH TRANSFORMERS AT-A-GLANCE

TOGETHER, WE WILL IMPROVE THE HEALTH

AND WELLBEING OF EVERYONE IN THE WORLD




MOVEMENT


COLORADO

ARE YOU BATTERIES INCLUDED?Take the Health Transformer Pledge

Take the Pledge at startuphealth.com

Documents

SHOOT FOR THE MOON! - DE Breast Cancerdebreastcancer.org/pdf/Dr._Krein_DBCC_StartUpHealth_FINAL_.pdf · The Healthcare Transformer Mindset™ and The Healthcare Transformer Mindset™are