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Snippets: Digitization of Medical Devices December 2019 These are the snippets from our report on Medical Devices Industry Trends and Opportunities for Technology Service Providers (TSP) CLICK HERE To access the full report

Snippets: Digitization of Medical Devices...03 Company Deep-dive Topics covered in the Snippets Report Topics covered in the Full Report 44 Source: Draup Major Players Note: Analysis

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Page 1: Snippets: Digitization of Medical Devices...03 Company Deep-dive Topics covered in the Snippets Report Topics covered in the Full Report 44 Source: Draup Major Players Note: Analysis

Snippets:

Digitization of Medical DevicesDecember 2019

These are the snippets from our report on Medical Devices Industry Trends and Opportunities for Technology Service Providers (TSP)

CLICK HERETo access the full report

Page 2: Snippets: Digitization of Medical Devices...03 Company Deep-dive Topics covered in the Snippets Report Topics covered in the Full Report 44 Source: Draup Major Players Note: Analysis

Source : DRAUP

2

2

Draup empowers sales teams with

comprehensive industry, account &

stakeholder intelligence to enable

microtargeting

www.draup.com

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33

Source: Draup

Ecosystem & Digitization Framework01

Key Digitization Themes02

AGENDA

Service/ Solution/ Partnerships/ Opportunities04

Recommendations05

Topics Covered• Overview• Digitization Themes• Medical Devices Technical Stack• Start-ups across digitization themes• R&D Spend by companies• R&D share by geography

Company Deep-dive03

Topics covered in the Snippets Report

Topics covered in the Full Report

Page 4: Snippets: Digitization of Medical Devices...03 Company Deep-dive Topics covered in the Snippets Report Topics covered in the Full Report 44 Source: Draup Major Players Note: Analysis

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Source: Draup

Major Players

Note: Analysis is based on the DRAUP’s proprietary engineering database, updated in November 2019

Primary and secondary research sources have been used to align the Digital use-cases enablers and themes

Early Detection of Diseases

Increasing access to care and decreasing healthcare delivery costs

Tailoring medical decisions according to the patient’s response or risk of disease

Detecting chronic diseases prior to their progression to decrease patient fatality

Problem Statement

Solution Providers

Digital Solutions

Digital Outcomes

Targeted Personal Care Remote Patient Monitoring

• Electronic health Records

• Point-of-Care Diagnostics

• Personalized Implants

• Precision Medicine

• Drug Delivery System

• Robotic Operations

• Telehealth

• Smart Pills

• Smart Monitoring Devices

• Fitness Trackers

• Medication Adherence System

• Computer-aided Diagnostics

• mHealth1

• Wearable

• Anomaly Detection

• Preventive Care

AI/ML Platform Electronic Health Records Connected Health Devices Big Data Mobile Apps

Overview: Medical Device companies are providing data backed anomaly detection and remote monitoring solutions to deliver personalized care and targeted treatments

1. mHelath: mobile Health

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➢ Digital revolution has paved the way to collect data from each patient remotely and analyse it using AI based algorithms

➢ It increase communication between healthcare professional and patients especially those who are chronically ill, elderly or premature children

Advantages

• Sensors for monitoring essential vital signs such as ECG reading, heart rate, blood pressure, temperature, blood glucose levels etc

• Monitoring proper adherence to medical regimen with edible sensors and smart pill boxes

➢ Interaction of various diseases with one another has made patient’s anatomy unique and more complex

➢ Personalized and targeted care is essential to understand and accurately treat a disease with better patient experience

Advantages

• Targeting the specific genes which can in-turn cure or decrease the progression of a disease

• Manufacturing unique implants/prosthesis using 3D printing technology according to patient’s needs

Digitization themes: Connecting critical applications, devices, and technologies—all highlyinterdependent—and ensuring that they communicate to each other is vital for a successful digital implementation

Note: Analysis is based on the DRAUP’s proprietary engineering database, updated in November 2019

Primary and secondary research sources have been used to align the Digital themes and use-cases

Personalized Care

Remote Monitoring

Early Diagnosis and Detection

➢ Rapid and accurate identification of the symptoms underlying the disease is one of the most important steps leading to its successful cure

➢ Early diagnosis can help in decreasing the clinical onset of rare and complex diseases thereby enhancing the quality of life

Advantages

• Using software to analyse the medical images for detection of even smallest changes

• Gene profiling for identifying mutated genes which might be inherited

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Remote Monitoring

Personalized careEarly Diagnosis and Detection

Note: Analysis is based on the DRAUP’s proprietary engineering database, updated in November 2019The illustrated list of companies is not exhaustive

Tech Stack: For connectivity and data enablement of medical devices, companies are reaching out to niche and full stack solution providers to accelerate solution deployment

Ap

plic

atio

ns

Infrastructure Security

Predictive Analytics

mHealth Apps

Artificial Intelligence/Machine Learning

Data management and Analytics Platforms

Connectivity Big Data

Pla

tfo

rm

Wearables

Co

mp

on

ents

&

Har

dw

are

Smart Pills/BoxesSmart Monitoring DevicesImaging Devices

Cloud

Network

1. EHR: Electronic Health Record

EHR1/EMR Personalized Implants Genomics

Medication Adherence Systems Telehealth Remote Monitoring

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Start-ups: Start-ups are major enablers of digital medical devices through their niche capabilities in the areas of teleHealth, Anomaly detection, precision medicine etc.

Personalized Care

Remote Monitoring

Early Diagnosis and Detection

Develops clinically approved genetic tests for assessing and providing preventive care for people with cardiovascular diseases

Anomaly Detection

Uses AI and advanced analytics to turn the data from lab tests and into predictive engine helping pharma firms to detect diseases early

Preventive Care

Analyze ECG, respiration, and motion data and deliver automated reports to physicians for early detection of cardiac arrhythmias

mHealth

Develops AI software to capture and interpret medical images from ultrasound exams at the point of care

Computer-aided Diagnostic

Provides electrophysiology technology solutions for cardiac imaging enabling personalized and adaptive approach to therapy

Personalized Therapy

Developing technology to trigger the body’s own natural blood flow regulation system for the treatment of high blood pressure and heart failure

Drug Delivery System

Develops proton therapy systems for use in radiation treatment for cancer patients with its HYPERSCAN pencil beam scanning solution

Precision Medicine

Manufactures proprietary implantable ophthalmic devices to improve vision of individuals with untreatable retinal disorders

Personalized Implant

Creates wearable biosensors for use inpatient and outpatient settings like hospital monitoring, post-discharge care and cardiac monitoring etc.

Smart Device

Uses AI platform for monitoring patient’s treatment progress by measuring changes in facial expression using computer vision and facial recognition

Telehealth

Makes digestible sensors for smart pills that can be used to tell a smartphone app whether patients have taken their medications

Smart Pills

Develops wearable physiology monitoring device to provide integrated solutions with connected hardware

Wearable

Note: The above analysis is based on the DRAUP’s proprietary database and insights from industry stakeholders and secondary research, updated as on November 2019

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R&D Spend: Top R&D spenders are majorly focused on developing analytics platforms and computer-aided diagnostic solutionsapart from their regular product development initiatives

$35 - 37 Bn

Total R&D Spend (2018)

R&

D S

pen

d (

in B

n)

Medical Devices companies

~62%R&D spend contribution by Top 5 R&D spenders

~28.5%Next 10 R&D spend

contribution ~9.5%R&D spend contribution by Rest

of the Companies

Note: Analysis is based on the DRAUP’s proprietary engineering database, updated in November 2019

Approximately 40 Medical devices companies are analysed

Top 5 R&D Spenders (2018)

Vendor R&D Spend

Roche Diagnostics $10.5-11.0 Bn

Medtronic PLC $2.0-2.5 Bn

Abbott Laboratories $2.0-2.5 Bn

Johnson & Johnson $1.5-1.8 Bn

GE Healthcare $0.9-1.0 Bn

Insights

• Medical device companies are highly focused on delivering solutions leveraging artificial intelligence and advanced analytics to gain higher market share

• The market will continue growing with 3D printing, advanced monitoring techniques and other innovations

Page 9: Snippets: Digitization of Medical Devices...03 Company Deep-dive Topics covered in the Snippets Report Topics covered in the Full Report 44 Source: Draup Major Players Note: Analysis

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Source: Draup

Rest of North

America

51%

Rest of Europe

15%

India

5%

78k – 80k

R&D Headcount

China

5%

Germany

8%

UK

3%

Bay Area

6%

Consolidated R&D Talent Footprint: Advancement of the healthcare ecosystem in North America and Europe demands sophisticated medical device solutions translated towards digitally enabled R&D workforce

Medical Devices R&D Footprint

• Medical Devices R&D is

consolidated in the United

States and is not very

globalised.

• Medical Devices OEMs

are not leveraging low-cost

talent hotspots like India

and China.

• Most of the hubs are

located in North America,

indicating that the decision

making is still governed

from the US

Hub Spoke AnalysisNorth America Europe APAC

59%

13%

28%

58%

16%

26%

33%

26%

41%

Outpost

Satellite

Hub

Insights

• Medical Devices R&D is consolidated in the United States and is not very globalized

• India and China are the emerging tech hotspots for medical device Companies as operating margins for medical devices are significantly high

• Most of the hubs are in North America owing to developed infrastructure, and adoption of new technologies, indicating that the decision-making is still governed from the US

Top

Players

(by R&D

presence)

Note: Analysis is based on the DRAUP’s proprietary engineering database, updated in November 2019

Japan

5%

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Source: Draup

AGENDA

Topics Covered• Early Diagnosis & Detection• Personalized Care• Remote Monitoring

Ecosystem & Digitization Framework01

Key Digitization Themes02

Service/ Solution/ Partnerships/ Opportunities04

Recommendations05

Company Deep-dive03

Topics covered in the Snippets Report

Topics covered in the Full Report

Page 11: Snippets: Digitization of Medical Devices...03 Company Deep-dive Topics covered in the Snippets Report Topics covered in the Full Report 44 Source: Draup Major Players Note: Analysis

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Early Diagnosis and Detection: Medical device companies are using wearable sensors and gene profiling techniques to detect even the minute symptoms for early detection of diseases

Computer-aided Diagnostics

Using software to analyze the medical images and automatically generate test reports

mHealth

Assessing chances of developing chronic disorders using data from health apps

Wearables

Collecting user’s vital signs using smart patches to detect earlier indications of diseases

Anomaly Detection

Knowing prevalence & severity of disease by comparing healthy and patient’s medical images

Preventive Care

Testing gene sequences for genetically- inherited disorders

Use-cases

Case-Studies

Major Players

Competitive Health is providing WellDoc’s diabetes management app ‘BlueStar’to its clients which captures blood-glucose related information from patient and transmit it to the doctor

Huami is integrating its smart watches and heart trackers with AliveCor’s heart care platform to bring new generation of medical functionality to wearable devices

Zilic uses ML algorithms to compare the healthy images with diseased images and automatically detect the disease

Note: Analysis is based on the DRAUP’s proprietary engineering database, updated in November 2019

Primary and secondary research sources have been used to align the Digital themes and use-cases

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Focused ultrasound into the brain for treating Parkinson’s disease

Solution to providing in-hospital ECG and cardiac Event Monitoring

Computer-aided Diagnostics mHealth Wearables Anomaly Detection Preventive Care

Collaborations: Major players are partnering with tech giants and specialized start-ups to leverage their capabilities for technologically advanced solutions

Acquisition Investment Partnership Inhouse

Dynamic Imaging

Note: Analysis is based on the DRAUP’s proprietary engineering database, updated in November 2019

Get insights & early indication of immunotherapy response

Web-based image and information management

Develop innovative electrophysiology technologies

Creating connected device for diabetes management

Molecular diagnostic test to screen non-small cell lung cancer

Offering Abbott’s FreeStyle to people with Type 2 diabetes

Testing and tracking blood glucose level

Design solutions for diagnosis of cardiac problems, sepsis etc.

Provide allergy testing with Plushcare’s telemedicine service

Studying the genetic factors underlying infertility in women

Early detection of sepsis in critically ill patients

Connected solution for diagnosis of lung cancer

Creating app for diagnosis of sleep apnea in babies

Develop sensitive digital bio-marker for early detection of AD1

Diagnostic tests to detect lung cancer at its earliest stages

Detection of irregular heart rhythm with ECG app

1: AD: Alzheimer’s Disease

App for guiding patients before and post surgery

Diagnosis of periprosthetic joint infection

Gather and analyze patient-reported feedback with Apple watch

Developing advanced diagnostic solution for preventing post

surgery infections

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Personalized Care: Companies are using 3D printing technology and Genomics to provide more targeted services with use cases like Personalized Implants and Precision Medicine

Electronic health Records

Keeping track of patient’s medical history to deliver targeted solutions

Personalized Implant

Using 3D printing to develop patient specific implants

Precision Medicine

Integrating genomic data with person’s medical record to deliver personalized solution

Drug Delivery System

Continuous monitoring and delivering of drug according to patient’s need

Robotic Operations

Tailoring surgical procedures according to patient’s need and anatomy

Use-cases

Case-Studies

Major Players

Hackensack Meridian Health is offering Mako System’s robotic arm which enables surgeons to personalize surgery according to patient’s anatomy

Johnson & Johnson has partnered with 3D Systems to leverage their 3D printing technology to manufacture personalized implants

Dexcom is offering Insulet’swearable device ‘OmniPod’ which is programmed to deliver insulin continuously into the skin

Point-of-Care Diagnostics

Deliver personalized services to patients with genetic disorders or chronic diseases

Note: Analysis is based on the DRAUP’s proprietary engineering database, updated in November 2019

Primary and secondary research sources have been used to align the Digital themes and use-cases

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Electronic Health Records POC1 Diagnostics Personalized Implant Precision Medicine Drug Delivery System Robotic Operations

Collaborations: Major players have acquired various start-ups specializing in precision medicine and robotic operations to provide seamless patient experience

iSuite

Note: Analysis is based on the DRAUP’s proprietary engineering database, updated in November 2019

Acquisition Investment Partnership Inhouse

Cloud-based solution to save patient test results

Providing Corindus’ precision robotics platform

Suite of POC diagnostic instruments for primary care

Personalized solution for spine surgery

Solutions eliminating repetitive diagnostic testing

Data sharing and analysis network

Robot-assisted surgery platform

Using AI to diagnose large vessel occlusion strokes

Implants to deliver electrical signals to the spinal cord

Develop continuous insulin delivery pump

Oncology-specific EHR software

Developed Point of Care Testing solution

Develop analytics solutions for cancer patients

Develop investigational wearable infusion devices

EHR connectivity platform

Advanced minimally invasive robotic surgery suites

BrightMatter Plan software for whole-brain tractography

Create customized instru-ment for knee replacement

Use clinical data platform to improve the effectiveness of

medical devices

Veritor point-of-care diagnostic system

Manufacturing customized implants using 3D printing

Next generation tools in for single cell genomic analysis

BD Hylok Glass Prefillable Syringe

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Remote Monitoring: Connected devices and sensor technology are enabling remote monitoring use cases like

fitness trackers and medication adherence systems

Telehealth

Distribution of health services through telecommunication technologies

Smart Pills

Monitoring medicine intake with pills equipped with edible electronic sensors

Smart Monitoring Devices

Monitor patient’s activity and effectiveness of the treatment through connected devices

Fitness Trackers

Tracking fitness-related metrics such as distance walked or run, calorie consumption, and in some cases heartbeat

Medication Adherence Systems

Ensuring proper adherence to medicine regimen using sensor enabled boxes and packaging

Use-cases

Case-Studies

Major Players

Dexcom and Verily co-developed continuous glucose monitoring patch using Verily’s miniaturised electronics platform and Dexcom’s sensor technology

Argentum has invested in AdhereTech who develops smart pill bottles which sends reminders on patient’s phone if a dose is missed

Henry Schein Medical is offering delivery of Medpod’s MobileDoc 2 telemedicine suitcase to remote locations via Uber Health

Note: Analysis is based on the DRAUP’s proprietary engineering database, updated in November 2019

Primary and secondary research sources have been used to align the Digital themes and use-cases

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Telehealth Smart Pills Smart Monitoring Devices Fitness TrackersMedication Adherence

Systems

Collaborations: Major players are partnering with other medical device and healthcare firms to deliver fitness tracking solutions and medication adherence systems

Note: Analysis is based on the DRAUP’s proprietary engineering database, updated in November 2019

Acquisition Investment Partnership Inhouse

Using mobile telehealth services into an array of Philips solutions

Automatically dispenses medication at pre-programmed times

Cloud-based healthcare platform for gathering data

Pulse oximetry sensor for monitoring heart rate

Develop products for home dialysis and critical care

Connected Health technologies to collect and share health data

Timely delivery of medicine to patients

Remote, continuous health monitoring data platform

Enable patient access to video-enabled telemedicine platform

Digital medicines equipped with Ingestible Sensors

Integrate data from CGM device, activity tracker into one app

Develop app to enable doctors to monitor drug adherence

Advance remote heart monitoring technology

Develop medicines with ingestible sensors for patients with mental illness

Abilify MyCite digital pill with sensor embedded in tablet

Virtual diabetes clinic enabling patients to manage medication

Aggregate data from health-tracking wearable devices

Develop a medication adherence pilot project

Second-generation continuous glucose monitoring system

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AGENDA

Topics CoveredKey activities and workloads aligned to digitization themes for following companies• Roche• Medtronic• Abbott Laboratories• GE Healthcare

Opportunities for Service Providers• Medical Device outsourcing overview• Service/solution providers key activities• Opportunity areas for solution/service

providers

Recommendations to Target Prospects

Ecosystem & Digitization Framework01

Key Digitization Themes02

Service/ Solution/ Partnerships/ Opportunities04

Recommendations05

Company Deep-dive03

Topics covered in the Snippets Report

Topics covered in the Full Report

CLICK HERETo access the full report

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33INDUSTRIES

240,000+COMPANIES ANALYSED

3,000+DATA SOURCES

2,500+GLOBAL’ LOCATIONS

3,000+TECHNOLOGY SERVICE PROVIDERS’

PARTNERSHIPS ANALYSED

1,300+BRAINDESK REPORTS

About Draup

1.2 M+CURATED GLOBAL EXECUTIVES

2,400+

UNIQUE ATTRIBUTES ANALYZED

300,000+DAILY SIGNALS ANALYSED

DRAUP Capabilities & Data Assets

LOCATION INTELLIGENCE

Explore Accounts,

Executives, R&DLocations and

Ecosystem Insights

ACCOUNT INTELLIGENCE

DIGITAL INTENTIONS

TOP DIGITAL USE-CASES

R&D CENTRE ANALYSIS

DIGITAL ROIMAPPER

STRATEGIC &TACTICAL SIGNALS

OUTSOURCING OPPORTUNITY

MAPPER

CLICK HERETo access the full report

CLICK HERETo access our whitepapers library