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“ORGANS OF THE IMMUNE SYSTEM” (BLOCK 7) SOAL dr. JUSUF FANTONI, SpPA 1. Primary lymphoid org ans i n human be ings a re : A. Muc osa – as soc iat ed lymphoi d tis sue (malt ) & peye r’s pa tches B. Bues a of fa br ic iu s & appendi x C. Tons il a nd splee n D. Bo ne mar row an d thymus 2. Bo ne ma rro w ha s one the following featur es : A. Str oma l ce lls sur vive eve n gi ven d ose radiat ion B. 90% of the pre- B cel ls di e if th ey fai l to fr om funct ion I g mol ecules C. Bone marr ow se rve s as a si te of maturat ion of T -Lymphocytes D. Verte brate inclu ding hu mans wi ll s urvive even a ll th e stem cell s are d estr oyed 3. Thymes has one of the followin g cha ra cteristics : A. Sit uat ed a bove the lungs a nd belo w the t hyr oid B. Is t he si te of producti on of T-Lymphocyt e C. The cortical l aye r i s cove red wit h macr opha ges D. Thymocyt es are ;ess in the me dul la 4. As an or gan of the i mmune sy stem, t hymus pla ys one of the f ol lowi ng r ol es : A. Fol lowing pubert y, t he t hymus be gins to enl arg e B. Mos t prec urs or T-cells mature in the medull a C. Maj ori ty of the prec urs or T-c ell s die in th e medu lla due to apoptosis D. Thymic epitheli al cells , int erdigi tat ing dendr iti c cel ls and mac rop hage s secrete soluble factors which influence T-cell maturation 5. Lymp h node has one t he fo ll owing his to logi ca l f eatures : A. Is a r ound-shaped organ wi th the size of more t han 3 C MS B. Mos t of t he fr ee ce ll s in t he no de ar e lymphoi d bla st ce ll s C. In a stimulate d node, a ger minal centr e may develo p wit hin t he pri mary nodule s D. Par acorte x are the are as be tween the caps ule a nd the cortes 6. One of the hi st ol og ica l f ind in gs of spl ee n i s : A. White pulp is t he small, oval/rounded grayi sh ar eas within the speni c cor d B. Mos t of the par ench yme of the spl een is red pil p C. Lymphocte s are the mai n resi dent cell popul ati on of the spl eni c cords D. The aged erythrocytes are removed by T-lymphocytes 7. Mucosa-associa ted lymphoid t is sue (mal t) h as o ne o f t he f ol lowi ng f eature s : A. Malt is located benea th t he mucos a epith eli a B. The immune respons e of mal t also t argete d agai nst co mponents of th e food C. Mal t pla sma ce ll s produce Ig G, rel eases ont o the epi thr lia l surf ace

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“ORGANS OF THE IMMUNE SYSTEM” (BLOCK 7)

SOAL dr. JUSUF FANTONI, SpPA

1. Primary lymphoid organs in human beings are :A. Mucosa – associated lymphoid tissue (malt) & peyer’s patches

B. Buesa of fabricius & appendix

C. Tonsil and spleenD. Bone marrow and thymus

2. Bone marrow has one the following features :A. Stromal cells survive even given dose radiation

B. 90% of the pre-B cells die if they fail to from function Ig molecules

C. Bone marrow serves as a site of maturation of T-LymphocytesD. Vertebrate including humans will survive even all the stem cells are destroyed

3. Thymes has one of the following characteristics :

A. Situated above the lungs and below the thyroidB. Is the site of production of T-Lymphocyte

C. The cortical layer is covered with macrophages

D. Thymocytes are ;ess in the medulla

4. As an organ of the immune system, thymus plays one of the following roles :

A. Following puberty, the thymus begins to enlargeB. Most precursor T-cells mature in the medulla

C. Majority of the precursor T-cells die in the medulla due to apoptosis

D. Thymic epithelial cells, interdigitating dendritic cells and macrophages secrete

soluble factors which influence T-cell maturation

5. Lymph node has one the following histological features :

A. Is a round-shaped organ with the size of more than 3 CMSB. Most of the free cells in the node are lymphoid blast cells

C. In a stimulated node, a germinal centre may develop within the primary nodules

D. Paracortex are the areas between the capsule and the cortes

6. One of the histological findings of spleen is :

A. White pulp is the small, oval/rounded grayish areas within the spenic cordB. Most of the parenchyme of the spleen is red pilp

C. Lymphoctes are the main resident cell population of the splenic cords

D. The aged erythrocytes are removed by T-lymphocytes

7. Mucosa-associated lymphoid tissue (malt) has one of the following features :

A. Malt is located beneath the mucosa epithelia

B. The immune response of malt also targeted against components of the foodC. Malt plasma cells produce IgG, releases onto the epithrlial surface

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D. Immune cell activation is the same as other lymphoid tissues 

8. Tonsils are lymphoid organs which have one of the features mentioned below :

A. Pharyngeal tonsil (adenoid) has deep crypt which facilitate the contact of 

antigens with the immune cellsB. Tonsil’s lymphoid nodules consist mainly of T-lymphocytes

C. Tonsils share histological features with lymph nodes i.e ;. With afferent and

efferent lymph vessels and reticular fibresD. Exposure to antigens relies on the contact of antigens with cells of the immune

system of the epithelia which cover the tonsils.

9. Gut-Associated lymphoid tissue (galt) has one of the characteristics below :

A. Are found only in the ileum and appendix

B. Peyer’s patches located beneath the epithelium extend to the submucosaC. The epithelia appears squamous which allows contact of antigens with cells of 

the immune systemD. T-Lymphocytes are predominant in galt.

10. To your understanding of the immune system, one of the following statements is

correct :

A. B and T-Lymphocytes originate from pluripotent stem cells in the bonemarrows.

B. T-Lymphocyte mainly developed and differentiated in thymus

C. Lymph nodes are bean shapes organs which are found mainly in the neck, axillaand inguinal area

D. When spleen is taken out of human body, that person will suffer reduced

immune response and toxicity.