Soal Gram Negative Blok7

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    1. A patient begain to receive intravenous antibiotics dissolved in sterile saline

    solution developed fever within an hour. (The solution in which antibiotics were

    dissolved had been sterilized by autoclaving.) The IV infusion was stopped and

    the fluid cultured, but cultures on a variety of media were sterile.

    Which of the following bacterial components would have been most effective inproducing the patient's fever?

    A. Spores

    B. Lipopolysaccharide.

    C. Capsule polysaccharide.

    D. Outer membrane proteins.

    E. Siderophores.

    2. Three days after an appendectomy, a patient develops high fever. The patient's

    vital signs include a dangerously low blood pressure. The patient's erythrocyte

    sedimentation rate (ESR) is above-normal. Which of the cytokines below most

    directly contributed to development of these symptoms?

    A. IL-4B. IFN-gamma

    C. IL-8

    D. IL-10

    E. TNF-alpha

    3. A hospitalized patient spikes a fever. Lactose-fermenting Gram-negative rods are

    isolated from a blood culture. Which of the following, produced in response to

    infection, played the largest role in producing the fever?

    A. C3b

    B. IL-1

    C. IL-2

    D. IL-8

    E. Interferon-alpha

    4. Toxin ofVibrio cholerae is:

    A. LOS

    B. Cholera toxin - activates adenylate cyclase

    C. Toxin A - enterotoxin

    D. LPS

    E. ShET 1

    5. The following statement are true of typhoid fever:

    A. The incubation period for enteric fever is 3-60 days, but symptoms

    typically occur in 3-5 weeksB. Patients who continue to shed bacteria for more than 1 month are

    considered chronic carriers

    C. Detection of persistently high H antibody offers an additional way of

    screening for long-term carriers

    D. Widal's test shows cross-reactivity with some otherSalmonella species

    E. Blood culture culture is more sensitive than bone marrow

    6. Drug of choice for enteric fever in children is:

    A. cotrimoxazole

    B. ceftriaxon

    C. chloramphenicol

    D. ampicillinE. quinolone

    http://www.med.jhu.edu/medcenter/quiz/objQuery.cgi?actionField=query&dbfield=micro&queryTypeFld=contains&queryFld=Vibrio+choleraehttp://www.med.jhu.edu/medcenter/quiz/objQuery.cgi?actionField=query&dbfield=micro&queryTypeFld=contains&queryFld=Vibrio+cholerae
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    7. Oxygen requirements ofSalmonella spp. is:

    A. Microaerophilic

    B. Aerobic

    C. Facultative anaerobe

    D. Obligate anaerobe

    E. Obligate aerobe8. Morbidity ofBordetella pertussis is:

    A. Folliculitis

    B. Urinary tract infections

    C. Neonatal meningitis

    D. Conjunctivitis

    E. Whooping cough

    9. This specimen can give the highest positivity for Salmonella typhi culture

    A. blood

    B. urine

    C. faeces

    D. bone marrow aspirateE. bile aspirate

    10. Prolonged fever with neutropenia can be seen in

    A. dengue fever

    B. measles

    C. typhoid fever

    D. diphtheria

    E. varicella

    11. Toxin ofShigella spp. is:

    A. Yst II

    B. Enterotoxins

    C. Cholera toxin - activates adenylate cyclase

    D. Leukocidin

    E. LPS

    http://www.med.jhu.edu/medcenter/quiz/objQuery.cgi?actionField=query&dbfield=micro&queryTypeFld=contains&queryFld=Salmonella+spp.http://www.med.jhu.edu/medcenter/quiz/objQuery.cgi?actionField=query&dbfield=micro&queryTypeFld=contains&queryFld=Bordetella+pertussishttp://www.med.jhu.edu/medcenter/quiz/objQuery.cgi?actionField=query&dbfield=micro&queryTypeFld=contains&queryFld=Shigella+spp.http://www.med.jhu.edu/medcenter/quiz/objQuery.cgi?actionField=query&dbfield=micro&queryTypeFld=contains&queryFld=Salmonella+spp.http://www.med.jhu.edu/medcenter/quiz/objQuery.cgi?actionField=query&dbfield=micro&queryTypeFld=contains&queryFld=Bordetella+pertussishttp://www.med.jhu.edu/medcenter/quiz/objQuery.cgi?actionField=query&dbfield=micro&queryTypeFld=contains&queryFld=Shigella+spp.