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Sore throat – Global U&A

Questionnaire

Supplementary File 1

2

Methodology

30 minute online survey

Countries (TBC)

Australia N=400

Brazil N=400

China N=400

France N=400

Germany N=400

Philippines N=400

Russia N=400

Saudi Arabia N=400

Thailand N=400

UK N=400

USA N=400

South Africa N=400

Italy N=400

Target sample

Quotas

Broad Nat rep on Age Gender and SEG

This survey is being conducted on behalf of Incite, an independent market research agency.

Suffered sore throat or throat dryness in the past 12 months

Survey Design

Screener

Text in red provides guidance for programming of the online questionnaire: CLOSEEnd the surveyCONTINUEMove on to the next questionCHECK QUOTASCheck if the target number of respondents has been reached for the given demographicROTATE LISTChange the order of the answers in an answer list for each respondent, to avoid answer order biasONE CODE ONLY 1Only one answer permitted from the listASK ALLAll respondents to be asked the questionPIPE IN TREATMENTInsert an answer from a previous question into the next quetion

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We are conducting research about people’s experience of sore throat and throat dryness and would like to ask you some questions. The survey will take approximately 30 minutes of your time.

Most importantly, we would like to reassure you that all data generated in this research will remain anonymous at all times and will be treated in accordance with data protection laws. Your name or any other identifiable information will not be mentioned at any time in any of the written reports, connected to any data or disclosed to a third party.

S1. Do you work in any of the following industries? Please select all that apply.

1 Market research CLOSE 2 Marketing / Management consulting CLOSE 3 Advertising / Public relations CLOSE 4 Journalism / Media (TV, radio, newspaper, magazine

etc) CLOSE

7 Drugstore / pharmacy CLOSE 8 Manufacturer of healthcare / pharmaceutical products CLOSE 9 Healthcare / medical professionals CLOSE 10 Banking CONTINUE 11 Education CONTINUE 12 Telecommunications CONTINUE 13 None of the above CONTINUE

S2. Are you….?

1 Female CHECK QUOTAS 2 Male CHECK QUOTAS

S3. Which of the following age ranges do you fall into?

1 Under 18 years CLOSE 9 50-54 years CONTINUE AND CHECK QUOTAS

2 18-19 years CONTINUE AND CHECK QUOTAS

9 50-54 years 3 20-24 years 10 55-59 years4 25-29 years 11 60-64 years5 30-34 years 12 65-70 years6 35-39 years 13 Over 70 years CLOSE 7 40-44 years

8 45-49 years9 50-54 years

S4. Social class/income questions and quotas – see separate document

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S5. In which of these regions do you live? – see separate document

S6. In the last 12 months have you suffered from any of the following conditions, even if your condition/degree of suffering was only temporary or extremely mild?

Please choose all that apply

PLEASE ROTATE LIST

1 Headache CLOSE IF NOT ALSO

MENTIONED SORE OR DRY

THROAT

2 Backache

3 Sore throat CONTINUE 4 Dry throat CONTINUE 5 Dandruff or itchy/flaky scalp CLOSE IF NOT

ALSO MENTIONED

SORE OR DRY THROAT

6 Sleeplessness 7 Hayfever 8 Headache

None of these CLOSE

Record all drop out details.

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QSY1. How recently have you suffered from a sore or dry throat?

ONE CODE ONLY

QSY2. How many times have you suffered a sore or dry throat in the last 12 months?

ONE CODE ONLY

Now we would like you to think about the most recent time that you had a dry throat or sore throat. Please select all that apply to that occasion.

QSY3 Did you have any of these other symptoms the most recent time you had a sore or dry throat? Select all that apply.

ROTATE LIST

1 Dry, tickly cough 2 Chesty cough 3 Aches/ pains in the chest or body more

generally 4 Nasal/sinus congestion 5 Chest congestion 6 Sneezing 7 Had to keep clearing my throat 8 Other flu like symptoms eg Fever,

temperature, no energy, lethargic 9 Loss of voice 10 None of these

1 Within the past week 1 2 Within the past month 2 3 Within the past 3 months 3 4 Within the past 6 months 4 5 Within the past 12 months 5

1 Never 1 2 Once or twice a year 2 3 3-4 times a year 3 4 Every month of the year 4 5 Every week of the year 5 6 More than once a week 6

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Still thinking about the most recent time that you had a sore and/or dry throat.

QSY4. Thinking about the most recent time you suffered a sore or dry throat approximately how long did your symptoms last?

ONE CODE ONLY

1 Less than one day 1 2 One day 2 3 Two-three days 3 4 Four-five days 4 5 Six-seven days 5 6 More than a week 6

QSY5. Do you know, or think you know, what caused or led to the sore or dry throat that you had most recently?

ONE CODE ONLY

1 I know for sure what caused it ASK SY6 2 I think I know what caused it/ I have a good

idea what caused it ASK SY6

3 I have no idea what caused it GO TO SY7

QSY6. What was it that (INSERT CAUSED/ YOU THINK CAUSED FROM QSY5) your most recent sore or dry throat symptoms?

Please select all that apply.

PLEASE ROTATE LIST

1 Common cold/flu MEDICAL 2 Other bacterial or viral infection MEDICAL 3 Hayfever ENVIRONMENTAL 4 Specific allergy (excluding hayfever) ENVIRONMENTAL 5 Too much talking/shouting/singing ENVIRONMENTAL 6 General airborne pollution ENVIRONMENTAL 7 Dust or other specific environmental

conditions ENVIRONMENTAL

8 Smoking/Passive smoking ENVIRONMENTAL 9 Being in a crowded place ENVIRONMENTAL 10 Drinking too much alcohol the night

before ENVIRONMENTAL

11 Hot and dry indoor environment ENVIRONMENTAL 12 Air conditioning ENVIRONMENTAL 13 Sudden changes in

temperature/weather MEDICAL

14 Snoring ENVIRONMENTAL 16 Cold or cold and wet weather MEDICAL

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17 A change in seasons MEDICAL 18 Hot /Humid / Dry weather ENVIRONMENTAL 19 Got it from a child or family member ENVIRONMENTAL 20 Stress at home/work MEDICAL 21 Lack of sleep/ tiredness MEDICAL 22 Another cause (please write in) ENVIRONMENTAL

ASK ALL

QSY7. How important is it to you to know the cause of your throat symptoms?

ONE CODE ONLY

1 Not at all important 2 Not very important 3 Fairly important 4 Very important

QSY8. How would you describe the severity of the sore or dry throat that you suffered most recently?

Very mild Very severe

QSY9. Which of these describe how it felt physically when you had your most recent sore or dry throat?

Please select all that apply

PLEASE ROTATE LIST

1 Tickly 2 Scratchy 3 Itchy 4 Dry 5 Husky 6 Irritated 7 Prickly 8 Swollen 9 Tight 10 Hard to swallow 11 Stabbing sharp pain 1 Burning 13 Lump in throat 14 Cut throat 15 Painful to talk 16 Like I’ve swallowed barbed wire/broken glass 17 Inflamed

1 2 3 4 5 6 7 8 9 10

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18 Raw 19 Something else (please write in)

QSY10. Which of these describe how it made you feel emotionally when you had your most recent sore or dry throat?

Please select all that apply.

1 Miserable/Fed up 2 Isolated / cut off 3 Really Sad 4 No interest in socialising with friends and family 5 It reduced my appetite. 6 Couldn’t concentrate 7 Distracted 8 Agitated 9 Didn’t feel like myself 10 Self-conscious when talking to people

QSY11. Which of these applied to your most recent sore or dry throat? My throat symptoms were …

ONE CODE ONLY

1 Consistent through the day and night

2 Worse during the morning 3 Worse during the afternoon 4 Worse during the evening 5 Worse during the night 6 It varied day by day

Thank you for your responses so far. We would like you to continue to think about the most recent sore or dry throat you suffered from.

QT1. Thinking about the most recent time you suffered with your throat did you do anything at all to treat it or help deal with the symptoms?

ONE CODE ONLY

1 Yes 2 No

ASK ALL

QT2. And thinking about previous times that you have experienced SIMILAR throat symptoms, how often did you do something to treat it?

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ONE CODE ONLY

1 Always 2 Often 3 Sometimes 4 Never 5 I haven’t suffered throat symptoms before

ASK ALL WHO TREATED AT QT1 (CODE 1) IF NOT TREATED AT ALL (CODE2) SKIP TO QT10

QT3. On this occasion how long was it from when you first started to notice your throat symptoms to when you started to do something to treat them?

ONE CODE ONLY

1 within an hour 2 within half a day 3 within a day 4 two or three days 5 within a week 6 within two weeks 7 longer than two weeks

QT4. Thinking about the throat symptoms you had most recently, what was it that made you do something about it?

Please select all that apply.

1 I didn’t want the symptoms to get worse 2 The symptoms interfered with my day to

day activities 3 I didn’t want new symptoms to start 4 The symptoms had got worse 5 The symptoms interfered with sleep 6 The symptoms were agonizing 7 Although not agonizing the symptoms

were very unpleasant 8 the symptoms were not going away 9 I was advised by doctor/nurse 10 I was advised by Pharmacist/ pharmacist

assistant 11 I was advised by Family/friends 12 Something else (please write in)

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QT5a. Which of these did you use or do for the throat symptoms you experienced most recently?

Please select all that apply.

PLEASE ROTATE. IF MORE THAN ONE USED AT QT5a.ASK:

QT5b. And which of these treatments did you use first?

QT5c. And which second?

QT5d. and which third

QT5e and which would you say was your MAIN treatment? ONE CODE ONLY

Use at all

Use first

Use second

Use Third

Main treatment

1 Antibiotics 2 Medicated sore throat

remedies 3 Prescription treatment 4 Natural/alternative

treatment 5 Home remedies 6 Analgesics/Pain killers 7 Drinking water/ fluids 8 Confectionary, sweets,

chewing gum

QT6a.Thinking about ALL the things you used which of these statements BEST applies to how you used them?

ONE CODE ONLY

I used the same treatments during both the day and night I used different treatments during the day than at night I only used treatments at all during the day I only used treatments at all during the night It varied

ASK ALL WHO USED MORE THAN ONE TREATMENT AT QT5a

QT6b. Still thinking about ALL the things you used for your most recent throat symptoms which of these next statements BEST applies to how you used them? ONE CODE ONLY

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I used the same ONE treatment all the way through I used several treatments all the way through I changed the treatments I was using during the course of the sore/dry throat

ASK ALL WHO USED MORE THAN ONE TREATMENT AT QT5a

FOR EACH USED AT QT5(a-d) ASK:

QT7. When during the episode of a sore or dry throat did you use/do this?

ONE CODE ONLY

Antib-iotics

Medicated sore throat remedies

Prescription treatment

Natural alternat-ives

Home remedies

Drinking/ fluids

Sweets

Mostly at the beginning All the way through Mostly at the end

QT8 TO BE ASKED ABOUT MAIN TREATMENT FROM QT5e AND up to 2 other treatments randomly selected from QT5a. PIPE IN TREATMENT BELOW QUESTION WORDING AT QT8.

QT8. Thinking now about (MAIN TREATMENT AUTO-FILL) Which of these were important to you when choosing which treatment to use? Which of these were important to you when choosing this treatment shown below?

Please select all that apply.

I wanted something which….

PLEASE ROTATE WITHIN LISTS AND KEEP LISTS SEPARATE.

LIST ONE 1 Soothes the throat 2 Coats the throat 4 Relieves pain 5 Moistens the throat 7 Treats infection

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8 Cleanses the throat

9 Numbs the throat

LIST TWO

10 I could feel working 11 Works quickly 12 Gives long lasting relief

13 Contains natural ingredients

14 Has a pleasant taste/ flavour 15 Was not expensive 16 Does not react with other medicines 17 Other members of my family can take 18 Healthcare professionals recommend

19 Comes in a format I like 20 Contains the active ingredient I prefer 21 Is a brand I trust 22 It has worked for me before

ASK ALL SUFFERING FROM SORE/DRY THROAT AT s6 (code 3/4) AND WHO TREATED AT ALL AT QT1 AND WHO DID NOT USE MEDICATED SORE THROAT REMEDIES (did NOT code 2 at QT5a), ASK QT9a.

QT9a For what reason/s didn’t you use Medicated sore throat remedies for your most recent sore throat symptoms?

Please choose all that apply.

PLEASE ROTATE STATEMENTS

1 advice from internet or other people 3 I was recovering/ would recover/ it would pass quickly 4 The symptoms were too severe for over-the-counter 5 Other treatments were (more) effective 6 I was advised to use something else by a healthcare professional 7 I prefer not to use medications generally 8 Symptoms were not bad enough/ disruptive enough 9 I don’t think these work for this sort of problem 10 Some other reason (please write in)

ASK ALL SUFFERING FROM SORE OR DRY THROAT AT s6 (code 3/4) AND WHO TREATED AT ALL AT QT1 AND WHO DID NOT USE OTHER MEDICINAL PRODUCTS (prescription and/or antibiotics at QT5a) AT ALL AT QT5a. (But could have selected ‘medicated sore throat remedies’ at QT5a).

QT9b For what reason/s didn’t you use other medicinal treatments (prescription treatment or antibiotics) for your most recent sore throat symptoms?

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Please choose all that apply.

PLEASE ROTATE STATEMENTS

1 advice from internet or other people 3 I was recovering/ would recover/ it would pass quickly 4 The symptoms were not severe enough for medicinal products 5 Other treatments were (more) effective 6 I was advised to use something else by a healthcare professional 7 I prefer not to use medications generally 8 Symptoms were not bad enough/ disruptive enough 9 I don’t think these work for this sort of problem 10 Some other reason (please write in)

ASK ALL WHO DID NOT TREAT AT QT1 OTHERWISE SKIP TO QIN1

QT10 Why didn’t you treat your sore /dry throat?

Please choose all that apply.

1 I was recovering/ would recover/ it would pass quickly

2 Symptoms were not bad enough/ disruptive enough

3 I don’t think treatments work

4 I couldn’t be bothered to treat it

5 I prefer not to use medications generally

6 None of these reasons

ASK ALL

Thank you for your answers so far.

QIN1. Which of these, if any, did you go to for advice when you experienced your most recent throat symptoms?

Please choose all that apply

1 GP/doctor 2 Specialist doctor/consultant 3 Pharmacist 4 Pharmacy assistant 5 looked online by searching my symptoms 6 Looked on a health website 7 Got information from TV, magazines or

newspapers 8 Friends and/or family

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9 Other (please write in) 10 None Skip to

QIN6

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ASK IF MORE THAN ONE HCP SEEN (CODE 1,2,3,4 AT QIN1.)

QIN2a.You mentioned that you had seen (insert HCP type coded 1-4 from QIN1) when you experienced your most recent throat symptoms?

Which of the healthcare professionals did you go to for advice first?

QIN2b And which did ask for advice second?

QIN2c. And third?

Q.IN2d. And fourth?

Please choose all that apply

First second Third Fourth 1 GP/doctor 2 Specialist

doctor/consultant

3 Pharmacist 4 Pharmacy assistant

ASK QIN3 IF SEEN PHARMACIST OR PHARMACY ASSISTANT (CODES 3 OR4 AT QIN1.) IF NOT SEEN SKIP TO QIN6

QIN3 When you saw the pharmacist or pharmacy assistant did they……?

ONE CODE ONLY

1 Recommend something to you which you bought/used Ask QIN4 2 Recommend something to you but you didn’t buy/use it ASK QIN5a/7 3 Not recommend anything to you ASK QIN5a/7

ASK IF SEEN PHARMACIST OR PHARMACY ASSISTANT (CODES 3 OR4 AT QIN1) AND CODED 1 AT QIN3, OTHERWISE SKIP TO QIN6

QIN4. What did the pharmacist/pharmacy assistant recommend?

Please choose all that apply

1 Antibiotics 2 Medicated sore throat remedies 3 Prescription treatment 4 Natural/alternative over the

counter treatment

6 Home remedies 9 Confectionary, sweets, chewing

gum

SHOW EACH PRODUCT RECOMMENDED AT QIN4

QIN5. On this occasion where did you buy/get this product?

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Antibiotics Medicated sore throat remedies

Prescription

1 Online 2 At my Drs

surgery/from my healthcare provider

3 At the pharmacy 4 At the Drugstore 5 From a general

supermarket /convenience store

6 Did not buy it – had it already

7 Other

ASK IF SEEN DOCTOR AT QIN1. OTHERWISE SKIP TO QIN6/7

QIN5a How strongly do you agree or disagree with the following statements about why you visit your doctor?

I want to be examined for the cause of my sore throat

I want Dr to give me something for pain

I want Dr to explain how serious my problem is

I want to know how soon I will recover

I want Dr to explain possible treatments

I feel anxious and would like Dr’s help

I want a note for sick leave for work

I want an antibiotic

I want to be referred to a specialist

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ASK ALL WHO DID NOT CONSULT ANY HCP AT QIN1.

QIN6. which of these reasons applies to why on this occasion you did not go to see a healthcare professional about your sore or dry throat

Please choose all that apply

1 I have been to see them with this problem before and do not need to go again

2 It was not serious enough to see a healthcare professional

3 It would be too inconvenient 4 It would have been too

expensive

5 There is nothing they can do for this sort of problem.

6 I don’t think it’s a health problem.

7 Another reason

ASK ALL

QIN7. Thinking now about pharmacist/pharmacy assistants how strongly do you agree or disagree with the following statements?

Please choose all that apply

Disagree strongly

Disagree Neither agree or disagree

Agree Agree strongly

They are more interested than the doctor in problems like a sore or dry throat.

I believe what they tell me

I would trust a brand more if it was recommended to me by a pharmacist or pharmacy assistant

I value the advice of the pharmacist or pharmacy assistant

They can tell me the cause of a sore/dry throat

They can tell me if I need to go to the Doctor.

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ASK ALL QB1a. Now we would like you to think about some brands that people may use for a sore or dry throat. Which of these brands have you heard of? Please choose all that apply IF RESPONDENT SELECTS ‘NONE’, SKIP TO QB4.

QB1b.Which of these brands have you personally used at all in the last 12 months? Please choose all that apply IF SELECT ‘NONE’, SKIP TO QB1E.

ASKQB1c ONLY IF TREATMENT USED AT QT1 (CODE 1)

QB1c. Which, if any, did you use last time you had a sore/dry throat? Please choose all that apply

ASK ALL

QB1d. Which ONE do you use most often?

ONE CODE ONLY

ASK FOR ALL AWARE OF (@QB1a) BUT NOT USED IN PAST 12 MONTHS

(@QB1b):

QB1e. Which of these would you consider using in the future?

Please choose all that apply

Aware Used AT ALL 12 months

Used LAST TIME

Used MOST

OFTEN

Would consider

1 See separate document for Brand lists for each country

2 3 4

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ASK FOR BRANDS AWARE OF AT QB1a

QB2. Here is a list of statements that some people have used to describe brands. Which of these statements would you associate with each of these brands?

It doesn’t matter if you don’t know the brand well, it is your impressions we are interested in, you can choose as many or as few statements as you like.

TBC You can feel it working It works quickly It gives long lasting relief It contains natural ingredients It has a pleasant taste/ flavour It is not expensive It does not react with other medicines

Other members of my family can take it too

Healthcare professionals recommend it

Comes in a format I like Contains the active ingredient I prefer

Is a brand I trust It a brand which has worked for me before

ASK QB3 FOR ALL BRANDS USED LAST TIME (QB1c) : ROTATE ORDER OF BRANDS IF NO BRANDS USED SKIP TO QB4

QB3. You said you have used [BRAND/S] on the most recent occasion you treated a dry or sore throat what format did this/these brand/s come in?

Please choose all that apply.

Brand 1 Brand 2 Brand 3 1 Suckable tablets 2 Liquid/Gargle 3 Lozenges 4 Solubles (in water) eg

Granules

5 Sprays

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QB4 Now we would like you to think about the formats that throat remedies come in which of these statements apply to each format. It doesn’t matter if you don’t know the format well, it is your impressions we are interested in, you can choose as many or as few statements as you like.

Please choose all that apply.

Suckable tablets

Liquid/Gargle Lozenges Solubles (in water) eg Granules

Sprays

Is best for really severe sore throat

Is most soothing

Is best for regular use

Works the fastest

Is best for moisturising the throat

Is pleasant to use

Lasts the longest

Is best to use for a dry or irritated throat

Is best for a moderately sore throat

Is best for the early stages of a sore throat

Is best for keeping your throat generally healthy

Comes in flavours I like

Is the easiest to use

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ASK ALL

Thank you for your answers so far, we have just a couple more questions for you. QAH1 How strongly do you agree or disagree with the following statements about Antibiotics?

Disagree strongly

Agree strongly

Antibiotics are generally effective against sore throats

1 2 3 4 5

Unnecessary use of antibiotics makes them become ineffective

Antibiotics speed up recovery

Antibiotics prevent a sore throat turning into something worse

I only use antibiotics if I absolutely have to

I like to use antibiotics straight away to prevent my symptoms getting worse

Q. Finally, which of the following best describes your employment status?

Please select one answer only

Full-time Part-time Student Retired Not employed Other (please specify)_________________

Check with panel if recorded elsewhere also children