Special Issue on “Mathematical Modelling and Simulation of ...downloads.hindawi.com/journals/cmmm/2002/162565.pdf · the subject of tumour growth modelling, there have also appeared

Special Issue on “Mathematical Modelling and Simulation ofAspects of Cancer Growth”

Preface to Special Issue

Over the past 10–15 years, there has been a notable

increase in the attention paid by the mathematical biology

community to modelling all aspects of tumour growth—

from the earliest stages of genetic mutations through to

solid tumour growth, invasion and metastasis. The

mathematical modelling of tumour growth, like its subject,

is definitely growing, expanding and “invading”! Indeed,

the area of modelling tumour growth has reached such a

stage that it is almost a well-established research field of

mathematical biology in its own right. The upsurge in

research has also been underpinned by several important

minisymposia on the subject at major international

mathematical biology and applied mathematics confer-

ences during the 1990s.

In addition to the increase in research articles per se on

the subject of tumour growth modelling, there have also

appeared two special issues of other journals:

(1) “Modelling and Simulation Problems on Tumor-

immune System Dynamics”, Mathematical and

Computer Modelling Volume 23, Number 6, March

1996, Guest Editor: Nicola Bellomo.

(2) “Mathematical Models for the Growth, Development

and Treatment of Tumours”, Mathematical Models

and Methods in Applied Sciences, Volume 9, Number

4, June 1999.

The current special issue of the Journal of Theoretical

Medicine may therefore be seen as the third in the above

“series”.

This particular special issue, devoted to modelling all

aspects of tumour growth and development, represents a

collection of articles from members of the recently funded

European Union Research Training Network “Using

Mathematical Modelling and Computer Simulation to

Improve Cancer Therapy”. The Network consists of eight

member departments (experimental and theoretical) in the

following institutions: Politecnico di Torino, Italy;

University of Oxford, UK; Universite J. Fourier, Grenoble,

France; University of Magdeburg, Germany; Institute for

Medical Bio-Mechanics, Israel; University of Warsaw,

Poland; University of Dundee, UK. The articles

themselves reflect the breadth and depth of approaches

(experimental and theoretical) that are being used to gain

deeper insight into a complex medical condition that still

causes many millions of deaths worldwide each year.

Finally, and most importantly, I would like to thank all

the authors for their contributions to this special issue and

hope that the field continues to grow and attract other

talented modellers who can interact with clinicians and

one day make a real impact in improving the treatment of

cancer through their mathematical models.

Mark Chaplain

Guest Editor

ISSN 1027-3662 q 2002 Taylor & Francis Ltd

DOI: 10.1080/10273660290015198

Journal of Theoretical Medicine, 2002 Vol. 4 (1), p. 1

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Special Issue on “Mathematical Modelling and Simulation of ...downloads.hindawi.com/journals/cmmm/2002/162565.pdf · the subject of tumour growth modelling, there have also appeared