8
Overcoming Repellency and Resistance in Cockroaches

Specific Benefits of Alpine Insecticides that Control …pestcontrol.basf.us/dsr/cockroach/overcoming-repellency-and... · insecticides because it disrupts energy production at multiple

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Page 1: Specific Benefits of Alpine Insecticides that Control …pestcontrol.basf.us/dsr/cockroach/overcoming-repellency-and... · insecticides because it disrupts energy production at multiple

Overcoming Repellency and Resistance in Cockroaches

Solve the Problems of Repellency and Resistance in Cockroaches

Use PT® Alpine pressurized insecticide, Alpine WSG insecticide, PT® Phantom II pressurized insecticide, and Phantom termiticide-insecticide as part of the BASF Complete Cockroach Control Protocol.

To find out more, contact your local BASF sales representative or visit pestcontrol.basf.us

Always read and follow label directions.

©2016 BASF Corporation. All rights reserved.PSS 16-20-936

Control Cockroaches in Challenging Environments

To your commercial kitchen customers, nothing is more important than their reputation. Sightings of cockroaches anywhere food is processed, stored, or served could damage their reputations, local health department ratings, and profitability. Yet, that’s a risk whenever insecticides demonstrating cockroach resistance and repellency are used in any commercial kitchen account.

BASF Complete Cockroach Protocol includes Alpine® and Phantom®

non-repellent insecticides. Together, Alpine and Phantom insecticides offer a cockroach solution that will:

• Eliminate repellency issues• Manage resistance• Protect your and your

customers’ reputations,local health departmentratings, and profitability

Specific Benefits of Alpine®

and Phantom® Insecticides that Control Cockroaches

Advantages of Alpine® WSG Water Soluble Granule and PT® Alpine® Pressurized Insecticides include:

• Fast-acting non-repellent insecticides: start killingcockroaches within minutes

• Scheduling flexibility per label: Crack & Crevice®,void, and spot treatments may be made while a foodhandling facility is in operation

• Reduced Risk Status: Contains dinotefuran, the onlyactive ingredient granted Reduced Risk Status by theEPA for use in both public health and food handlingestablishments

Advantages of Phantom® Termiticide-Insecticide and PT® Phantom® II Pressurized Insecticide include:

• Manages resistance: Unique mode of action reducesthe chance of developing resistance by disrupting energyproduction at multiple target sites within the cells of thecockroach

• Resists rapid breakdown: Insecticide is resistant to rapidbreakdown from moisture and extreme heat, as well ashigh pH environments associated with cleaning products infood handling accounts

• Faster performance: Crystallization technology ensuresbioavailability and faster performance on numeroussurfaces, including porous, non-porous, and highorganic matter

• Non-repellent insecticide: Highly effective, non-repellenttechnology that’s undetectable to roaches

InsecticidesInsecticides

“APPLICATIONS OF THIS PRODUCT IN FOOD/FEEDAREAS OF FOOD/FEED HANDLING ESTABLISHMENTSMAY BE MADE AS A CRACK & CREVICE, VOID, SPOT ORGENERAL TREATMENT. General surface application maybe used only when the facility is not in operation, providedexposed food/feed has been covered or removed from the area prior to application.”

Page 2: Specific Benefits of Alpine Insecticides that Control …pestcontrol.basf.us/dsr/cockroach/overcoming-repellency-and... · insecticides because it disrupts energy production at multiple

Overcoming Repellency and Resistance in Cockroaches

Solve the Problems of Repellency and Resistance in Cockroaches

Use PT® Alpine pressurized insecticide, Alpine WSG insecticide, PT® Phantom II pressurized insecticide, and Phantom termiticide-insecticide as part of the BASF Complete Cockroach Control Protocol.

To find out more, contact your local BASF sales representative or visit pestcontrol.basf.us

Always read and follow label directions.

©2016 BASF Corporation. All rights reserved.PSS 16-20-936

Control Cockroaches in Challenging Environments

To your commercial kitchen customers, nothing is more important than their reputation. Sightings of cockroaches anywhere food is processed, stored, or served could damage their reputations, local health department ratings, and profitability. Yet, that’s a risk whenever insecticides demonstrating cockroach resistance and repellency are used in any commercial kitchen account.

BASF Complete Cockroach Protocol includes Alpine® and Phantom® non-repellent insecticides. Together, Alpine and Phantom insecticides offer a cockroach solution that will:

• Eliminate repellency issues• Manage resistance• Protect your and your

customers’ reputations,local health departmentratings, and profitability

Specific Benefits of Alpine®

and Phantom® Insecticides that Control Cockroaches

Advantages of Alpine® WSG Water Soluble Granule and PT® Alpine® Pressurized Insecticides include:

• Fast-acting non-repellent insecticides: start killingcockroaches within minutes

• Scheduling flexibility per label: Crack & Crevice®,void, and spot treatments may be made while a foodhandling facility is in operation

• Reduced Risk Status: Contains dinotefuran, the onlyactive ingredient granted Reduced Risk Status by theEPA for use in both public health and food handlingestablishments

Advantages of Phantom® Termiticide-Insecticide and PT® Phantom® II Pressurized Insecticide include:

• Manages resistance: Unique mode of action reducesthe chance of developing resistance by disrupting energyproduction at multiple target sites within the cells of thecockroach

• Resists rapid breakdown: Insecticide is resistant to rapidbreakdown from moisture and extreme heat, as well ashigh pH environments associated with cleaning products infood handling accounts

• Faster performance: Crystallization technology ensuresbioavailability and faster performance on numeroussurfaces, including porous, non-porous, and highorganic matter

• Non-repellent insecticide: Highly effective, non-repellenttechnology that’s undetectable to roaches

InsecticidesInsecticides

“APPLICATIONS OF THIS PRODUCT IN FOOD/FEEDAREAS OF FOOD/FEED HANDLING ESTABLISHMENTSMAY BE MADE AS A CRACK & CREVICE, VOID, SPOT ORGENERAL TREATMENT. General surface application maybe used only when the facility is not in operation, providedexposed food/feed has been covered or removed from the area prior to application.”

Page 3: Specific Benefits of Alpine Insecticides that Control …pestcontrol.basf.us/dsr/cockroach/overcoming-repellency-and... · insecticides because it disrupts energy production at multiple

Overcoming Repellency and Resistance in Cockroaches

Solve the Problems of Repellency and Resistance in Cockroaches

Use PT® Alpine pressurized insecticide, Alpine WSG insecticide, PT® Phantom II pressurized insecticide, and Phantom termiticide-insecticide as part of the BASF Complete Cockroach Control Protocol.

To find out more, contact your local BASF sales representative or visit pestcontrol.basf.us

Always read and follow label directions.

©2016 BASF Corporation. All rights reserved.PSS 16-20-936

Control Cockroaches in Challenging Environments

To your commercial kitchen customers, nothing is more important than their reputation. Sightings of cockroaches anywhere food is processed, stored, or served could damage their reputations, local health department ratings, and profitability. Yet, that’s a risk whenever insecticides demonstrating cockroach resistance and repellency are used in any commercial kitchen account.

BASF Complete Cockroach Protocol includes Alpine® and Phantom® non-repellent insecticides. Together, Alpine and Phantom insecticides offer a cockroach solution that will:

• Eliminate repellency issues• Manage resistance• Protect your and your

customers’ reputations,local health departmentratings, and profitability

Specific Benefits of Alpine®

and Phantom® Insecticides that Control Cockroaches

Advantages of Alpine® WSG Water Soluble Granule and PT® Alpine® Pressurized Insecticides include:

• Fast-acting non-repellent insecticides: start killingcockroaches within minutes

• Scheduling flexibility per label: Crack & Crevice®,void, and spot treatments may be made while a foodhandling facility is in operation

• Reduced Risk Status: Contains dinotefuran, the onlyactive ingredient granted Reduced Risk Status by theEPA for use in both public health and food handlingestablishments

Advantages of Phantom® Termiticide-Insecticide and PT® Phantom® II Pressurized Insecticide include:

• Manages resistance: Unique mode of action reducesthe chance of developing resistance by disrupting energyproduction at multiple target sites within the cells of thecockroach

• Resists rapid breakdown: Insecticide is resistant to rapidbreakdown from moisture and extreme heat, as well ashigh pH environments associated with cleaning products infood handling accounts

• Faster performance: Crystallization technology ensuresbioavailability and faster performance on numeroussurfaces, including porous, non-porous, and highorganic matter

• Non-repellent insecticide: Highly effective, non-repellenttechnology that’s undetectable to roaches

InsecticidesInsecticides

“APPLICATIONS OF THIS PRODUCT IN FOOD/FEEDAREAS OF FOOD/FEED HANDLING ESTABLISHMENTSMAY BE MADE AS A CRACK & CREVICE, VOID, SPOT ORGENERAL TREATMENT. General surface application maybe used only when the facility is not in operation, providedexposed food/feed has been covered or removed from the area prior to application.”

Page 4: Specific Benefits of Alpine Insecticides that Control …pestcontrol.basf.us/dsr/cockroach/overcoming-repellency-and... · insecticides because it disrupts energy production at multiple

JWAX* Alpine Gel Rot. 1 + Alpine WSGJWAX Alpine Gel Rot. 1 + PhantomJWAX Control

CIN** Alpine Gel Rot. 1 + Alpine WSGCIN Alpine Gel Rot. 1 + PhantomCIN ControlAlpine® and Phantom® non-repellent insecticides will kill cockroaches and

protect your and your customers’ reputations.

Using non-residual, repellent insecticides, such as pyrethrins, in your commercial kitchen accounts can be useful in flushing cockroaches from harborage areas. On the other hand, using repellent, residual pyrethroid insecticides increases the risk of unwanted roach sightings and bait contamination during and following treatment.

Repellent Insecticides Cause Cockroaches to Scatter

• Does NOT fragment or spread cockroaches into more sensitive areas likedining rooms and reception areas

• Does NOT stop roaches from foraging across a treated surface• Does NOT contaminate Alpine cockroach gel bait placements• Does NOT interfere with roaches feeding on bait or around treated area• Does NOT disrupt cockroach feeding behavior if bait placements are nearby

Figure 1: Results show that neither Phantom® termiticide-insecticide nor Alpine® WSG Water Soluble Granule insecticide interfere with feeding on bait placements when applied on or around treated areas.

“Alpine® cockroach gel bait rotation 1 reservoir/Alpine WSG insecticide was the most effective treatment and gave 100± 0% mortality within 3 hours of bait application in susceptible and bait-averse German cockroaches and American cockroaches. No repellency was observed in any cockroach strain/species when the Alpine cockroach gel bait rotation 1 reservoir was treated with Alpine WSG insecticide.”

Dr. Buczkowski

Figures 2 & 3: Results show combination treatment of PT® Phantom II pressurized insecticide sprayed on top of Alpine® cockroach gel bait create a clear advantage over bait alone.

• PT Phantom II pressurized insecticide increased Alpine cockroach gel bait consumption for German cockroaches

• PT Phantom II pressurized insecticide and Alpine cockroach gel bait combo treatment results in high mortality across species and strains

*JWAX = Susceptible German roach strain **CIN = Bait averse German roach strain

Grzesiek Buczkowski, Ph.D. Center for Urban and Industrial Pest Management, Dept. of Entomology, Purdue University. Roach Baiting – Laboratory, 2013.

Grzesiek Buczkowski, Ph.D. Center for Urban and Industrial Pest Management, Dept. of Entomology, Purdue University. Roach Bait Consumption – Laboratory, 2012.

100

3 HAT

100100100

1 10 010

0

100100 100 100 10089 88

70

12 HAT 1 DAT

Alpine Cockroach Gel Bait Rotation 1

Alpine Cockroach Gel Bait Rotation 1 + PT Phantom II Pressurized Insecticide

Untreated Control

4.8

7.0

2.6

0.2

2.8

2.0

1.0

1.7

3.1

2.2

2.0

3.4

bait take bait takerat chow rat chow

G. RoachesSusceptible

(JWAX Strain)

G. RoachesBait Averse(CIN Strain)

Product

Sustainable Approach to Managing Cockroach Resistance

• Residual Insecticide Rotation Plan: Alpine andPhantom insecticides both contain different modes ofaction, active ingredients, and classes of chemistry thatare also different from pyrethroids

• Phantom’s Chemistry Minimizes the Chance of Developing Resistance:

- Its active ingredient, chlorfenapyr, is a pro-insecticide- Chlorfenapyr’s mode of action (uncouplers of oxidative

phosphorylation) is different from all other registeredinsecticides because it disrupts energy production atmultiple target sites within the cells

Pyrethroid is neutralized by insect’s own enzymes as part of its metabolism

Molecule is altered by the insect’s own internal process

Sprayed on or around insect

Cockroaches are less likely to develop resistance to

Phantom pro-insecticides because:

Chlorfenapyr in its original form

Advantages of Phantom pro-insecticides:

• After entering the insect, it is metabolized into achemical form that is more toxic to the insect thanin its original form

• Since the insect’s own chemical reaction createsthe more toxic form of the active ingredient,the chance of developing resistance to the activeingredient is minimized

Limitations to pyrethroid insecticides:

• Insects use their internal enzymes to break downinsecticides, such as pyrethroids

• Resistant strains may possess higher levels or moreefficient forms of these enzymes

• Insects destroy the toxin or quickly rid their bodiesof the toxic molecules

Alpine Cockroach Gel Bait Rotation 1 + PT Phantom II Pressurized InsecticideAlpine Cockroach Gel Bait Rotation 1

100908070605040302010

06 HAT 12 HAT 1 DAT 2 DAT 3 DAT 4 DAT 1 WAT 2 WAT

Figure 3:German Cockroach CIN Strain:Male and Female Mortality to Various Baits

Figure 2:German Cockroach Bait Consumption Susceptible vs. Bait Averse

Perc

ent M

orta

lity

Figure 1: Average % Mortality of Treatments

Insect Survives Insect Dies

100%

CI

Br

F3C N

CN

O

CI

Br

F3C N

CN

O

A.I. interacts withthe insect’s internalmetabolism

CI

Br

F3C N

H

CNMore toxic version is created inside insect

Using pyrethroid products on pyrethroid resistant cockroach strains is risky to your commercial kitchen business. The treatment result could cost you time and money for retreatments, as well as jeopardize your commercial kitchen customers’ reputations, local health department ratings, and profitability.

Cockroaches may become resistant to traditional insecticides

like pyrethroids because:

A pyrethroid in its original form

H3C

CH3 CH3H3C

O

O

H3C

O

CH2

Pyrethroid processed within insect

Non-repellent

Alpine and Phantom insecticides provide a more sustainable approach to killing strains of pyrethroid resistant roaches.

Avert® DF Dry Flowable InsecticideUntreated Control

N

OManage Resistance in Cockroaches with a Residual Insecticide Rotation Plan:

1. Apply PT Alpine or Alpine WSG insecticides duringregular service visits (e.g. weekly/monthly calls)

2. Apply PT Phantom II pressurized insecticide orPhantom termiticide-insecticide quarterly whenrotating Alpine cockroach gel bait rotation 1 and2 reservoirs

Strains of a species no longer react negatively to a particular active ingredient.

When roach populations are exposed to insecticides containing the same active ingredient, those with the resistant gene survive.

The survivors reproduce and pass on their resistance to their offspring.

The resistant population grows. The cycle is repeated when the same insecticide is continually used.

Over time the resistant roaches will become numerous in population.

How Insecticide Resistance Occurs

Phantom Pro-Insecticides: An Element to Managing Resistance

Page 5: Specific Benefits of Alpine Insecticides that Control …pestcontrol.basf.us/dsr/cockroach/overcoming-repellency-and... · insecticides because it disrupts energy production at multiple

JWAX* Alpine Gel Rot. 1 + Alpine WSGJWAX Alpine Gel Rot. 1 + PhantomJWAX Control

CIN** Alpine Gel Rot. 1 + Alpine WSGCIN Alpine Gel Rot. 1 + PhantomCIN ControlAlpine® and Phantom® non-repellent insecticides will kill cockroaches and

protect your and your customers’ reputations.

Using non-residual, repellent insecticides, such as pyrethrins, in your commercial kitchen accounts can be useful in flushing cockroaches from harborage areas. On the other hand, using repellent, residual pyrethroid insecticides increases the risk of unwanted roach sightings and bait contamination during and following treatment.

Repellent Insecticides Cause Cockroaches to Scatter

• Does NOT fragment or spread cockroaches into more sensitive areas likedining rooms and reception areas

• Does NOT stop roaches from foraging across a treated surface• Does NOT contaminate Alpine cockroach gel bait placements• Does NOT interfere with roaches feeding on bait or around treated area• Does NOT disrupt cockroach feeding behavior if bait placements are nearby

Figure 1: Results show that neither Phantom® termiticide-insecticide nor Alpine® WSG Water Soluble Granule insecticide interfere with feeding on bait placements when applied on or around treated areas.

“Alpine® cockroach gel bait rotation 1 reservoir/Alpine WSG insecticide was the most effective treatment and gave 100± 0% mortality within 3 hours of bait application in susceptible and bait-averse German cockroaches and American cockroaches. No repellency was observed in any cockroach strain/species when the Alpine cockroach gel bait rotation 1 reservoir was treated with Alpine WSG insecticide.”

Dr. Buczkowski

Figures 2 & 3: Results show combination treatment of PT® Phantom II pressurized insecticide sprayed on top of Alpine® cockroach gel bait create a clear advantage over bait alone.

• PT Phantom II pressurized insecticide increased Alpine cockroach gel bait consumption for German cockroaches

• PT Phantom II pressurized insecticide and Alpine cockroach gel bait combo treatment results in high mortality across species and strains

*JWAX = Susceptible German roach strain **CIN = Bait averse German roach strain

Grzesiek Buczkowski, Ph.D. Center for Urban and Industrial Pest Management, Dept. of Entomology, Purdue University. Roach Baiting – Laboratory, 2013.

Grzesiek Buczkowski, Ph.D. Center for Urban and Industrial Pest Management, Dept. of Entomology, Purdue University. Roach Bait Consumption – Laboratory, 2012.

100

3 HAT

100100100

1 10 010

0

100100 100 100 10089 88

70

12 HAT 1 DAT

Alpine Cockroach Gel Bait Rotation 1

Alpine Cockroach Gel Bait Rotation 1 + PT Phantom II Pressurized Insecticide

Untreated Control

4.8

7.0

2.6

0.2

2.8

2.0

1.0

1.7

3.1

2.2

2.0

3.4

bait take bait takerat chow rat chow

G. RoachesSusceptible

(JWAX Strain)

G. RoachesBait Averse(CIN Strain)

Product

Sustainable Approach to Managing Cockroach Resistance

• Residual Insecticide Rotation Plan: Alpine andPhantom insecticides both contain different modes ofaction, active ingredients, and classes of chemistry thatare also different from pyrethroids

• Phantom’s Chemistry Minimizes the Chance of Developing Resistance:

- Its active ingredient, chlorfenapyr, is a pro-insecticide- Chlorfenapyr’s mode of action (uncouplers of oxidative

phosphorylation) is different from all other registeredinsecticides because it disrupts energy production atmultiple target sites within the cells

Pyrethroid is neutralized by insect’s own enzymes as part of its metabolism

Molecule is altered by the insect’s own internal process

Sprayed on or around insect

Cockroaches are less likely to develop resistance to

Phantom pro-insecticides because:

Chlorfenapyr in its original form

Advantages of Phantom pro-insecticides:

• After entering the insect, it is metabolized into achemical form that is more toxic to the insect thanin its original form

• Since the insect’s own chemical reaction createsthe more toxic form of the active ingredient,the chance of developing resistance to the activeingredient is minimized

Limitations to pyrethroid insecticides:

• Insects use their internal enzymes to break downinsecticides, such as pyrethroids

• Resistant strains may possess higher levels or moreefficient forms of these enzymes

• Insects destroy the toxin or quickly rid their bodiesof the toxic molecules

Alpine Cockroach Gel Bait Rotation 1 + PT Phantom II Pressurized InsecticideAlpine Cockroach Gel Bait Rotation 1

100908070605040302010

06 HAT 12 HAT 1 DAT 2 DAT 3 DAT 4 DAT 1 WAT 2 WAT

Figure 3:German Cockroach CIN Strain:Male and Female Mortality to Various Baits

Figure 2:German Cockroach Bait Consumption Susceptible vs. Bait Averse

Perc

ent M

orta

lity

Figure 1: Average % Mortality of Treatments

Insect Survives Insect Dies

100%

CI

Br

F3C N

CN

O

CI

Br

F3C N

CN

O

A.I. interacts withthe insect’s internalmetabolism

CI

Br

F3C N

H

CNMore toxic version is created inside insect

Using pyrethroid products on pyrethroid resistant cockroach strains is risky to your commercial kitchen business. The treatment result could cost you time and money for retreatments, as well as jeopardize your commercial kitchen customers’ reputations, local health department ratings, and profitability.

Cockroaches may become resistant to traditional insecticides

like pyrethroids because:

A pyrethroid in its original form

H3C

CH3 CH3H3C

O

O

H3C

O

CH2

Pyrethroid processed within insect

Non-repellent

Alpine and Phantom insecticides provide a more sustainable approach to killing strains of pyrethroid resistant roaches.

Avert® DF Dry Flowable InsecticideUntreated Control

N

OManage Resistance in Cockroaches with a Residual Insecticide Rotation Plan:

1. Apply PT Alpine or Alpine WSG insecticides duringregular service visits (e.g. weekly/monthly calls)

2. Apply PT Phantom II pressurized insecticide orPhantom termiticide-insecticide quarterly whenrotating Alpine cockroach gel bait rotation 1 and2 reservoirs

Strains of a species no longer react negatively to a particular active ingredient.

When roach populations are exposed to insecticides containing the same active ingredient, those with the resistant gene survive.

The survivors reproduce and pass on their resistance to their offspring.

The resistant population grows. The cycle is repeated when the same insecticide is continually used.

Over time the resistant roaches will become numerous in population.

How Insecticide Resistance Occurs

Phantom Pro-Insecticides: An Element to Managing Resistance

Page 6: Specific Benefits of Alpine Insecticides that Control …pestcontrol.basf.us/dsr/cockroach/overcoming-repellency-and... · insecticides because it disrupts energy production at multiple

JWAX* Alpine Gel Rot. 1 + Alpine WSGJWAX Alpine Gel Rot. 1 + PhantomJWAX Control

CIN** Alpine Gel Rot. 1 + Alpine WSGCIN Alpine Gel Rot. 1 + PhantomCIN ControlAlpine® and Phantom® non-repellent insecticides will kill cockroaches and

protect your and your customers’ reputations.

Using non-residual, repellent insecticides, such as pyrethrins, in your commercial kitchen accounts can be useful in flushing cockroaches from harborage areas. On the other hand, using repellent, residual pyrethroid insecticides increases the risk of unwanted roach sightings and bait contamination during and following treatment.

Repellent Insecticides Cause Cockroaches to Scatter

• Does NOT fragment or spread cockroaches into more sensitive areas likedining rooms and reception areas

• Does NOT stop roaches from foraging across a treated surface• Does NOT contaminate Alpine cockroach gel bait placements• Does NOT interfere with roaches feeding on bait or around treated area• Does NOT disrupt cockroach feeding behavior if bait placements are nearby

Figure 1: Results show that neither Phantom® termiticide-insecticide nor Alpine® WSG Water Soluble Granule insecticide interfere with feeding on bait placements when applied on or around treated areas.

“Alpine® cockroach gel bait rotation 1 reservoir/Alpine WSG insecticide was the most effective treatment and gave 100± 0% mortality within 3 hours of bait application in susceptible and bait-averse German cockroaches and American cockroaches. No repellency was observed in any cockroach strain/species when the Alpine cockroach gel bait rotation 1 reservoir was treated with Alpine WSG insecticide.”

Dr. Buczkowski

Figures 2 & 3: Results show combination treatment of PT® Phantom II pressurized insecticide sprayed on top of Alpine® cockroach gel bait create a clear advantage over bait alone.

• PT Phantom II pressurized insecticide increased Alpine cockroach gel bait consumption for German cockroaches

• PT Phantom II pressurized insecticide and Alpine cockroach gel bait combo treatment results in high mortality across species and strains

*JWAX = Susceptible German roach strain **CIN = Bait averse German roach strain

Grzesiek Buczkowski, Ph.D. Center for Urban and Industrial Pest Management, Dept. of Entomology, Purdue University. Roach Baiting – Laboratory, 2013.

Grzesiek Buczkowski, Ph.D. Center for Urban and Industrial Pest Management, Dept. of Entomology, Purdue University. Roach Bait Consumption – Laboratory, 2012.

100

3 HAT

100100100

1 10 010

0

100100 100 100 10089 88

70

12 HAT 1 DAT

Alpine Cockroach Gel Bait Rotation 1

Alpine Cockroach Gel Bait Rotation 1 + PT Phantom II Pressurized Insecticide

Untreated Control

4.8

7.0

2.6

0.2

2.8

2.0

1.0

1.7

3.1

2.2

2.0

3.4

bait take bait takerat chow rat chow

G. RoachesSusceptible

(JWAX Strain)

G. RoachesBait Averse(CIN Strain)

Product

Sustainable Approach to Managing Cockroach Resistance

• Residual Insecticide Rotation Plan: Alpine andPhantom insecticides both contain different modes ofaction, active ingredients, and classes of chemistry thatare also different from pyrethroids

• Phantom’s Chemistry Minimizes the Chance of Developing Resistance:

- Its active ingredient, chlorfenapyr, is a pro-insecticide- Chlorfenapyr’s mode of action (uncouplers of oxidative

phosphorylation) is different from all other registeredinsecticides because it disrupts energy production atmultiple target sites within the cells

Pyrethroid is neutralized by insect’s own enzymes as part of its metabolism

Molecule is altered by the insect’s own internal process

Sprayed on or around insect

Cockroaches are less likely to develop resistance to

Phantom pro-insecticides because:

Chlorfenapyr in its original form

Advantages of Phantom pro-insecticides:

• After entering the insect, it is metabolized into achemical form that is more toxic to the insect thanin its original form

• Since the insect’s own chemical reaction createsthe more toxic form of the active ingredient,the chance of developing resistance to the activeingredient is minimized

Limitations to pyrethroid insecticides:

• Insects use their internal enzymes to break downinsecticides, such as pyrethroids

• Resistant strains may possess higher levels or moreefficient forms of these enzymes

• Insects destroy the toxin or quickly rid their bodiesof the toxic molecules

Alpine Cockroach Gel Bait Rotation 1 + PT Phantom II Pressurized InsecticideAlpine Cockroach Gel Bait Rotation 1

100908070605040302010

06 HAT 12 HAT 1 DAT 2 DAT 3 DAT 4 DAT 1 WAT 2 WAT

Figure 3:German Cockroach CIN Strain:Male and Female Mortality to Various Baits

Figure 2:German Cockroach Bait Consumption Susceptible vs. Bait Averse

Perc

ent M

orta

lity

Figure 1: Average % Mortality of Treatments

Insect Survives Insect Dies

100%

CI

Br

F3C N

CN

O

CI

Br

F3C N

CN

O

A.I. interacts withthe insect’s internalmetabolism

CI

Br

F3C N

H

CNMore toxic version is created inside insect

Using pyrethroid products on pyrethroid resistant cockroach strains is risky to your commercial kitchen business. The treatment result could cost you time and money for retreatments, as well as jeopardize your commercial kitchen customers’ reputations, local health department ratings, and profitability.

Cockroaches may become resistant to traditional insecticides

like pyrethroids because:

A pyrethroid in its original form

H3C

CH3 CH3H3C

O

O

H3C

O

CH2

Pyrethroid processed within insect

Non-repellent

Alpine and Phantom insecticides provide a more sustainable approach to killing strains of pyrethroid resistant roaches.

Avert® DF Dry Flowable InsecticideUntreated Control

N

OManage Resistance in Cockroaches with a Residual Insecticide Rotation Plan:

1. Apply PT Alpine or Alpine WSG insecticides duringregular service visits (e.g. weekly/monthly calls)

2. Apply PT Phantom II pressurized insecticide orPhantom termiticide-insecticide quarterly whenrotating Alpine cockroach gel bait rotation 1 and2 reservoirs

Strains of a species no longer react negatively to a particular active ingredient.

When roach populations are exposed to insecticides containing the same active ingredient, those with the resistant gene survive.

The survivors reproduce and pass on their resistance to their offspring.

The resistant population grows. The cycle is repeated when the same insecticide is continually used.

Over time the resistant roaches will become numerous in population.

How Insecticide Resistance Occurs

Phantom Pro-Insecticides: An Element to Managing Resistance

Page 7: Specific Benefits of Alpine Insecticides that Control …pestcontrol.basf.us/dsr/cockroach/overcoming-repellency-and... · insecticides because it disrupts energy production at multiple

JWAX* Alpine Gel Rot. 1 + Alpine WSGJWAX Alpine Gel Rot. 1 + PhantomJWAX Control

CIN** Alpine Gel Rot. 1 + Alpine WSGCIN Alpine Gel Rot. 1 + PhantomCIN ControlAlpine® and Phantom® non-repellent insecticides will kill cockroaches and

protect your and your customers’ reputations.

Using non-residual, repellent insecticides, such as pyrethrins, in your commercial kitchen accounts can be useful in flushing cockroaches from harborage areas. On the other hand, using repellent, residual pyrethroid insecticides increases the risk of unwanted roach sightings and bait contamination during and following treatment.

Repellent Insecticides Cause Cockroaches to Scatter

• Does NOT fragment or spread cockroaches into more sensitive areas likedining rooms and reception areas

• Does NOT stop roaches from foraging across a treated surface• Does NOT contaminate Alpine cockroach gel bait placements• Does NOT interfere with roaches feeding on bait or around treated area• Does NOT disrupt cockroach feeding behavior if bait placements are nearby

Figure 1: Results show that neither Phantom® termiticide-insecticide nor Alpine® WSG Water Soluble Granule insecticide interfere with feeding on bait placements when applied on or around treated areas.

“Alpine® cockroach gel bait rotation 1 reservoir/Alpine WSG insecticide was the most effective treatment and gave 100± 0% mortality within 3 hours of bait application in susceptible and bait-averse German cockroaches and American cockroaches. No repellency was observed in any cockroach strain/species when the Alpine cockroach gel bait rotation 1 reservoir was treated with Alpine WSG insecticide.”

Dr. Buczkowski

Figures 2 & 3: Results show combination treatment of PT® Phantom II pressurized insecticide sprayed on top of Alpine® cockroach gel bait create a clear advantage over bait alone.

• PT Phantom II pressurized insecticide increased Alpine cockroach gel bait consumption for German cockroaches

• PT Phantom II pressurized insecticide and Alpine cockroach gel bait combo treatment results in high mortality across species and strains

*JWAX = Susceptible German roach strain **CIN = Bait averse German roach strain

Grzesiek Buczkowski, Ph.D. Center for Urban and Industrial Pest Management, Dept. of Entomology, Purdue University. Roach Baiting – Laboratory, 2013.

Grzesiek Buczkowski, Ph.D. Center for Urban and Industrial Pest Management, Dept. of Entomology, Purdue University. Roach Bait Consumption – Laboratory, 2012.

100

3 HAT

100100100

1 10 010

0

100100 100 100 10089 88

70

12 HAT 1 DAT

Alpine Cockroach Gel Bait Rotation 1

Alpine Cockroach Gel Bait Rotation 1 + PT Phantom II Pressurized Insecticide

Untreated Control

4.8

7.0

2.6

0.2

2.8

2.0

1.0

1.7

3.1

2.2

2.0

3.4

bait take bait takerat chow rat chow

G. RoachesSusceptible

(JWAX Strain)

G. RoachesBait Averse(CIN Strain)

Product

Sustainable Approach to Managing Cockroach Resistance

• Residual Insecticide Rotation Plan: Alpine andPhantom insecticides both contain different modes ofaction, active ingredients, and classes of chemistry thatare also different from pyrethroids

• Phantom’s Chemistry Minimizes the Chance of Developing Resistance:

- Its active ingredient, chlorfenapyr, is a pro-insecticide- Chlorfenapyr’s mode of action (uncouplers of oxidative

phosphorylation) is different from all other registeredinsecticides because it disrupts energy production atmultiple target sites within the cells

Pyrethroid is neutralized by insect’s own enzymes as part of its metabolism

Molecule is altered by the insect’s own internal process

Sprayed on or around insect

Cockroaches are less likely to develop resistance to

Phantom pro-insecticides because:

Chlorfenapyr in its original form

Advantages of Phantom pro-insecticides:

• After entering the insect, it is metabolized into achemical form that is more toxic to the insect thanin its original form

• Since the insect’s own chemical reaction createsthe more toxic form of the active ingredient,the chance of developing resistance to the activeingredient is minimized

Limitations to pyrethroid insecticides:

• Insects use their internal enzymes to break downinsecticides, such as pyrethroids

• Resistant strains may possess higher levels or moreefficient forms of these enzymes

• Insects destroy the toxin or quickly rid their bodiesof the toxic molecules

Alpine Cockroach Gel Bait Rotation 1 + PT Phantom II Pressurized InsecticideAlpine Cockroach Gel Bait Rotation 1

100908070605040302010

06 HAT 12 HAT 1 DAT 2 DAT 3 DAT 4 DAT 1 WAT 2 WAT

Figure 3:German Cockroach CIN Strain:Male and Female Mortality to Various Baits

Figure 2:German Cockroach Bait Consumption Susceptible vs. Bait Averse

Perc

ent M

orta

lity

Figure 1: Average % Mortality of Treatments

Insect Survives Insect Dies

100%

CI

Br

F3C N

CN

O

CI

Br

F3C N

CN

O

A.I. interacts withthe insect’s internalmetabolism

CI

Br

F3C N

H

CNMore toxic version is created inside insect

Using pyrethroid products on pyrethroid resistant cockroach strains is risky to your commercial kitchen business. The treatment result could cost you time and money for retreatments, as well as jeopardize your commercial kitchen customers’ reputations, local health department ratings, and profitability.

Cockroaches may become resistant to traditional insecticides

like pyrethroids because:

A pyrethroid in its original form

H3C

CH3 CH3H3C

O

O

H3C

O

CH2

Pyrethroid processed within insect

Non-repellent

Alpine and Phantom insecticides provide a more sustainable approach to killing strains of pyrethroid resistant roaches.

Avert® DF Dry Flowable InsecticideUntreated Control

N

OManage Resistance in Cockroaches with a Residual Insecticide Rotation Plan:

1. Apply PT Alpine or Alpine WSG insecticides duringregular service visits (e.g. weekly/monthly calls)

2. Apply PT Phantom II pressurized insecticide orPhantom termiticide-insecticide quarterly whenrotating Alpine cockroach gel bait rotation 1 and2 reservoirs

Strains of a species no longer react negatively to a particular active ingredient.

When roach populations are exposed to insecticides containing the same active ingredient, those with the resistant gene survive.

The survivors reproduce and pass on their resistance to their offspring.

The resistant population grows. The cycle is repeated when the same insecticide is continually used.

Over time the resistant roaches will become numerous in population.

How Insecticide Resistance Occurs

Phantom Pro-Insecticides: An Element to Managing Resistance

Page 8: Specific Benefits of Alpine Insecticides that Control …pestcontrol.basf.us/dsr/cockroach/overcoming-repellency-and... · insecticides because it disrupts energy production at multiple

Overcoming Repellency and Resistance in Cockroaches

Solve the Problems of Repellency and Resistance in Cockroaches

Use PT® Alpine pressurized insecticide, Alpine WSG insecticide, PT® Phantom II pressurized insecticide, and Phantom termiticide-insecticide as part of the BASF Complete Cockroach Control Protocol.

To find out more, contact your local BASF sales representative or visit pestcontrol.basf.us

Always read and follow label directions.

©2016 BASF Corporation. All rights reserved.PSS 16-20-936

Control Cockroaches in Challenging Environments

To your commercial kitchen customers, nothing is more important than their reputation. Sightings of cockroaches anywhere food is processed, stored, or served could damage their reputations, local health department ratings, and profitability. Yet, that’s a risk whenever insecticides demonstrating cockroach resistance and repellency are used in any commercial kitchen account.

BASF Complete Cockroach Protocol includes Alpine® and Phantom® non-repellent insecticides. Together, Alpine and Phantom insecticides offer a cockroach solution that will:

• Eliminate repellency issues• Manage resistance• Protect your and your

customers’ reputations,local health departmentratings, and profitability

Specific Benefits of Alpine®

and Phantom® Insecticides that Control Cockroaches

Advantages of Alpine® WSG Water Soluble Granule and PT® Alpine® Pressurized Insecticides include:

• Fast-acting non-repellent insecticides: start killingcockroaches within minutes

• Scheduling flexibility per label: Crack & Crevice®,void, and spot treatments may be made while a foodhandling facility is in operation

• Reduced Risk Status: Contains dinotefuran, the onlyactive ingredient granted Reduced Risk Status by theEPA for use in both public health and food handlingestablishments

Advantages of Phantom® Termiticide-Insecticide and PT® Phantom® II Pressurized Insecticide include:

• Manages resistance: Unique mode of action reducesthe chance of developing resistance by disrupting energyproduction at multiple target sites within the cells of thecockroach

• Resists rapid breakdown: Insecticide is resistant to rapidbreakdown from moisture and extreme heat, as well ashigh pH environments associated with cleaning products infood handling accounts

• Faster performance: Crystallization technology ensuresbioavailability and faster performance on numeroussurfaces, including porous, non-porous, and highorganic matter

• Non-repellent insecticide: Highly effective, non-repellenttechnology that’s undetectable to roaches

InsecticidesInsecticides

“APPLICATIONS OF THIS PRODUCT IN FOOD/FEEDAREAS OF FOOD/FEED HANDLING ESTABLISHMENTSMAY BE MADE AS A CRACK & CREVICE, VOID, SPOT ORGENERAL TREATMENT. General surface application maybe used only when the facility is not in operation, providedexposed food/feed has been covered or removed from the area prior to application.”