Specific ImmunityBy Tanner Hamilton, Asia Thofield

The Immune System

What The Immune System

How it works•Proteins on cell surface•Immune memory

Innate Immune System•General defense•Usually bacterial infections

Adaptive Immune System•Learned throughout life•Specific Immunity•Usually used against bacteria and viruses

that change regularly•Quicker responses

T Cells•Type of white blood cell•Makes up adaptive immune system

Killer T-Cells•Attacks other cells•Can “see” into other cells•Also known as “Cytotoxic”

Helper T-Cells•Leads other T-Cells, B-cells, and other

immune response cells•Express CD4 co-receptor

General Facts about T-Cells•Cause of all autoimmune responses•Cause of transplanted organ rejection•Some allergic reactions•1/50 T-Cells are actually found in blood

Development of a T-Cell•Created in Lymph Nodes•Matures in Thymus

HIV•Infection occurs when bodily fluids are

exchanged• Human Immunodeficiency Virus

How HIV Reproduces •Uses CD4 Cells•Inserts genetic information into the host

cells nucleus•Reassembles itself and then pushes out of

the host cell while stealing necessary components

How HIV affects T-Cells and The Body•Undetermined cause of death for the T-

Cell•Lowers T-Cell count to dangerous levels•Healthy adult=  500 cells/mm3 to 1,200

cells/mm3•HIV infected adult= Less than 200

cell/mm3•Can cause  acquired immune deficiency

syndrome

References•http://www.webmd.com/a-to-z-guides/com

ponents-of-the-immune-system•http://www.tcells.org/beginners/tcells/•https://www.aids.gov/hiv-aids-basics/just-d

iagnosed-with-hiv-aids/understand-your-test-results/cd4-count/

•http://www.the-scientist.com/?articles.view/articleNo/38739/title/How-HIV-Destroys-Immune-Cells/