HOCL2000

SPORICIDAL VETERINARY

DISINFECTANT

ANIGENE HOCL2000 has been developed to meet the demands of Veterinary departments seeking fast

sporicidal disinfection without compromising materials compatibility. Hypochlorous acid has been used for

many years within the food industry and more recently as a stable endoscope sterilising fluid for Automated

Endoscope Washer Disinfectors.

This new and patented near pH neutral solution produces instantaneous levels of Hypochlorous acid from

specially designed sachets within a trigger spray that can be activated with water as and when it is required, via

a package that is fully compliant according to CLP and Transport regulations.

TRUSTED INFECTION CONTROL

Use Biocides Safely. Always read the label and product information before use

ANIGENE HOCL2000 has been designed to meet the demands of swift clinical disinfection without the

concerns of materials compatibility experienced by certain oxidising chemicals. Based on a unique patented

formulation that generates the required levels of Hypochlorous Acid by mixing a base and activator in-situ.

HOCL2000 is effective against a broad range of microorganisms. It is non-irritant and non-corrosive at

proper usage concentrations. (1)

MICROBIOLOGICAL AND REGULATORY SUMMARY

• Independently tested as Sporicidal, Tuberculocidal, Virucidal, Yeasticidal, Fungicidal and Bactericidal

according to recognised EN test protocols and is effective against viral pathogens such as Canine

Parvovirus, Feline Calicivirus, FIV, FeLV, Feline Panleucopenia, etc

• Rapidly sporicidal (Clostridium difficile) in 1 minute in clean and dirty conditions and also effective

against TB in 1 minute in clean and dirty conditions.

• Tested by University of Cambridge Biotechnology Department to be effective at denaturing /

precipitating DNA / RNA in 5 minutes.

• Manufactured in the UK in accordance with the requirements of ISO 9001 – HOCL2000 is a British

product concept with international patents both granted and pending.

• HOCL2000 is compliant with Article 95 of the Biocidal Products Regulations (PT3 - Veterinary

Hygiene).

HOW TO USE

• Packaged in a 750ml Trigger Spray ready for mixing.

• Simply remove trigger head, add 750ml of water, reseal the trigger spray, leave for approximately 5

minutes and gently swirl bottle prior to use.

• Solution may be kept for up to 7 days post mixing

GENERAL

• Whilst sporicidal efficacy is generally only required for specialist applications and not routine use,

HOCL2000 is ideal for use in conjunction with a disinfection programme including ANIGENE

NaDCC (floors, DEFRA requirements, Giardia, etc.) and AIRGENE Aerosol Disinfectant for Deep

Clean applications

• ANIGENE HLD4V continues to represent the most economic, materials safe and routine

disinfectant for broad spectrum applications.

SPORICIDAL ACTIVITY

Clostridium difficile HIRL 250ppm Clean EN13704 1 min > LOG 5

Clostridium difficile HIRL 2000ppm Dirty EN13704 1 min > LOG 6

BACTERICIDAL ACTIVITY

Escherichia coli HIRL 250ppm Clean EN13727 1 min > LOG 5

Escherichia coli HIRL 250ppm Dirty EN13727 1 min > LOG 5

Staphylococcus aureus HIRL 250ppm Clean EN13727 1 min > LOG 5

Pseudomonas aeruginosa HIRL 250ppm Clean EN13727 1 min > LOG 5

TUBERCULOCIDAL ACTIVITY

Mycobacterium terrae HIRL 2000ppm Dirty EN14348 1 min > LOG 7

…….

…….

Full test data available upon request

Hypochlorous Acid (HOCL) has been widely tested for medical, environmental, food and

other related markets against the following organisms: -

Bacillus subtilis var niger, Desulfovibrio indonensis, Clostridium difficile, Helicobacter pylori, Vancomycin resistant Enterococcus species, Candida albicans, Various Mycobacterium species (avium, chelonei, smegmatis, tuberculosis), Pseudomonas aeruginosa, E.coli 0157, Enterococcus faecalis, Polio virus type 2 Sabin strain,

Duck hepatitis B virus, HIV-1 strain3036, MSSA, MRSA, VRSA, Avian Flu, Micrococcus luteus, Corynebacterium amycolatum, Haemophilus influenza, Proteus mirabilis, Klebsiella pneumoniae, Salmonella paratyphi, Vibrio cholera, Cholera phage viruses, Streptococcus pyrogenes and Aspergillus niger.

Hypochlorous Acid Reference Papers

1. M. Eryilmaz and I. M. Palabiyik (2012) Tropical Journal of Pharmaceutical Research February 2013; 12(1); 123-126. “hypochlorous acid – Analytical

Methods and Antimicrobial Activity

2. V. Zinkevich, I.B. Beech, R.Tapper, I. Bogdarnia (2000) Journal of Hospital Infection 46: 153-156; The effect of Super-oxidised water on Escherichia

coli.

3. H. Hays, P.R. Elliker, and W.E. Sandine (1966) Applied Microbiology, page 575-581; Microbial Destruction by Low Concentrations of Hypochlorite and

lodophor Germicides in Alkaline and Acidic Water.

4. I.B. Beech,V. Zinkevich, J.A. Sunner, C.C. Gaylarde, (2007) Technical Report; Evaluation of the effect of Salvox (Stabilised HOCl) on Planktonic

Populations of model marine bacteria: Aerobic slime forming bacterium of the Pseudomonas Genus and anaerobic sulphate-reducing bacterium

Desulfovibrio alaskensis.

5. J.B. Selkon, G.W. Cherry, J.M. Wilson, M.A. Hughes (2006) Evaluation of Hypochlorous acid washes in the treatment of chronic venous leg ulcers.

6. N. Shetty, S. Srinivasan, J. Holton, G.L. Ridgway, J.B. Selkon (1997) Evaluation of Microbicidal activity of a new disinfectant; against vegetative

Bacteria, Spores, Candida albicans, Mycobacterium species and Viruses.

7. N. Shetty, S. Srinivasan, J. Holton and G.L. Ridgway (1999) Journal of Hospital Infection 41:101-105 Evaluation of microbiocidal activity of a new disinfectant:

Sterilox 2500 against Clostridium difficile spores, Helicobacter pylori, vancomycin resistant Enterococcus species, Candida albicans and several

Mycobacterium species.

8. J.B. Selkon, R.B. Babb, R. Morris (1999) Evaluation of the antimicrobial activity of a new super-oxidised water. Sterilox for the disinfection of endoscopes.

9. J.B. Selkon, A. Crossley (2009) Analysis of Hypochlorous Acid.

10. J. Lorrain Smith, A. Murray Drennan,Theodore Rettie, and William Campbell Experimental Observations on the antiseptic action of Hypochlorous acid and its application to wound treatment. Br Med J Jul 1915; 2: 129 - 136; doi:10.1136/bmj.2.2847.129.

11. Hypochlorous acid as a potential wound care agent. Journal of burns and Wounds April 11th Nov 2011. Registered Office: Dairy Cottage, Rulholme, Irthington, Carlisle Cumbria CA6 4NQ Company No: 690784

12. International journal of food microbiology 1987 page 183-186, the effect of ph on hypochlorite as a disinfectant, Granum, Magnusson.

For more information on our products or for technical support contact:

T: 08452 22 33 44

F: 01732 763530

info@medi-mark.co.uk

www.medi-mark.co.uk

HOCL2000 has been tested under the following EN test protocols: -

EN13704 Chemical disinfectants. Quantitative suspension test for the evaluation of sporicidal activity of chemical disinfectants

used in food, industrial, domestic and institutional areas. Test method and requirements (phase 2, step 1)

Bacillus subtilis, Clostridium

difficile

EN14348 Chemical disinfectants and antiseptics. Quantitative suspension test for the evaluation of Mycobactericidal activity of

chemical disinfectants in the medical area including instrument disinfectants. Test methods and requirements (phase

2, step 1)

Mycobacterium terrae

EN14476 Chemical disinfectants and antiseptics. Virucidal quantitative suspension test for chemical disinfectants and

antiseptics used in human medicine. Test method and requirements (phase 2, step 1)

Poliovirus, Adenovirus,

Norovirus, HIV

EN1650 Chemical disinfectants and antiseptics. Quantitative suspension test for the evaluation of fungicidal or yeasticidal

activity of chemical disinfectants and antiseptics used in food, industrial, domestic and institutional areas. Test

method and requirements (phase 2, step 1)

Aspergillus niger, Candida

albicans

EN13727 Chemical disinfectants and antiseptics. Quantitative suspension test for the evaluation of bactericidal activity of

chemical disinfectants for instruments used in the medical area. Test method and requirements (Phase 2/Step 1)

Enterococcus hirae,

Staphylococcus aureus,

Pseudomonas aeruginosa

EN13697 Chemical disinfectants and antiseptics. Quantitative non-porous surface test for the evaluation of bactericidal and/or

fungicidal activity of chemical disinfectants used in food, industrial, domestic and institutional areas. Test method and

requirements without mechanical action (phase 2/step 2)

Escherichia coli,

Staphylococcus aureus,

Pseudomonas aeruginosa

TRUSTED INFECTION CONTROL