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School of Mathematics and Natural Sciences University of Wuppertal, Germany Status of the EduGATE Project Uwe Pietrzyk with contributions from Mirjam Lenz, Kai Benning

Status of the EduGATE Project - IN2P3 Events Directory ... · nworking on novel PET detector for a new UHF MRI compatible BrainPET insert nmultiple simulation studies, with and without

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Page 1: Status of the EduGATE Project - IN2P3 Events Directory ... · nworking on novel PET detector for a new UHF MRI compatible BrainPET insert nmultiple simulation studies, with and without

School of Mathematics and Natural SciencesUniversity of Wuppertal, Germany

Status of the EduGATE Project

Uwe Pietrzykwith contributions from

Mirjam Lenz, Kai Benning

Page 2: Status of the EduGATE Project - IN2P3 Events Directory ... · nworking on novel PET detector for a new UHF MRI compatible BrainPET insert nmultiple simulation studies, with and without

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PROF. DR. UWE PIETRZYKSTATUS OF THE EDUGATE PROJECTGATE ACTIVITIES @ WUPPERTAL

n new Master course at University of Wuppertal (international/english)n topic: imaging in medicinen focus on physical and computational background of imaging in

medicine, including computer simulation

n special topics: imaging for medical applicationsn application of simulation à system design etc.n image reconstructionn image analysis and data visualisation

Computer Simulation In Science (CSIS)

Page 3: Status of the EduGATE Project - IN2P3 Events Directory ... · nworking on novel PET detector for a new UHF MRI compatible BrainPET insert nmultiple simulation studies, with and without

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PROF. DR. UWE PIETRZYKSTATUS OF THE EDUGATE PROJECTGATE ACTIVITIES @ WUPPERTAL

n new Master course at University of Wuppertal (international/english)n topic: imaging in medicinen focus on physical and computational background of imaging in

medicine, including computer simulation

n based to a large part on:– GATE– ROOT / C++– but also: develop / use Python-based analysis interface

including tools for image reconstruction

Computer Simulation In Science (CSIS)

Page 4: Status of the EduGATE Project - IN2P3 Events Directory ... · nworking on novel PET detector for a new UHF MRI compatible BrainPET insert nmultiple simulation studies, with and without

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PROF. DR. UWE PIETRZYKSTATUS OF THE EDUGATE PROJECTGATE ACTIVITIES @ WUPPERTAL

n installation of GATE / EduGATE project on university cluster

n Easy-GATE-installation-master

à students have easy access to GATE / EduGATE

à students use the same GATE and ROOT version

à used during lecture & exercises

Computer Simulation In Science (CSIS)

Page 5: Status of the EduGATE Project - IN2P3 Events Directory ... · nworking on novel PET detector for a new UHF MRI compatible BrainPET insert nmultiple simulation studies, with and without

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PROF. DR. UWE PIETRZYKSTATUS OF THE EDUGATE PROJECTGATE ACTIVITIES @ WUPPERTAL

n teach it in an IEEE Short Course: à Atlanta 2017, Sydney 2018, Manchester 2019?

n initially EduGATE was intended to provide very simple introductory examples to support newcomers using GATE

n simple and very basic examples turned out to be useful during lecturesà basic detector & imaging physicsà helpful for courses with students from different study programmes

(physics, engineering, computer sciences,...)

Motivation to extend the EduGATE project

Using GATE to Educate à EduCGATE

Page 6: Status of the EduGATE Project - IN2P3 Events Directory ... · nworking on novel PET detector for a new UHF MRI compatible BrainPET insert nmultiple simulation studies, with and without

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PROF. DR. UWE PIETRZYKSTATUS OF THE EDUGATE PROJECTGATE ACTIVITIES @ WUPPERTAL

n Coin_Chanfrom coincidence channel to a PET systemextended version: studying „scatter“ effects

n Gamma_Camerabasic imaging features of a Gamma camera

n SPECT_to_Recoincluding reconstruction from projections (based on IDL / GDL)needs new reco part based on C++ / Python / Fiji

n Spectroanalysing energy spectra of radioactive isotopeslinking to the book „Physics in Nuclear Medicine“ (Cherry et al.)

List of Examples – Collection 2018+GATE v7.2 GATE v8.0

Page 7: Status of the EduGATE Project - IN2P3 Events Directory ... · nworking on novel PET detector for a new UHF MRI compatible BrainPET insert nmultiple simulation studies, with and without

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PROF. DR. UWE PIETRZYKSTATUS OF THE EDUGATE PROJECTGATE ACTIVITIES @ WUPPERTAL

n Spectrometry_Gammaactually two modules (basic & extended)linking to the book „Physics in Nuclear Medicine“ (Cherry et al.)

n MR_PETavailable in two versions, Particle and Ion Sourcesexplore the fate of positron or electron in a MR system

n Attenuation*a Monte Carlo approach based on an „unrealistic“ system

n Cherenkov*optical photons, cherenkov and scintillation à fast PET detectors

n Multilayer_PET*expectations for higher spatial resolution using 1 to 4 crystal layers

n +

List of Examples – Collection 2018+GATE v7.2 GATE v8.0

Page 8: Status of the EduGATE Project - IN2P3 Events Directory ... · nworking on novel PET detector for a new UHF MRI compatible BrainPET insert nmultiple simulation studies, with and without

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PROF. DR. UWE PIETRZYKSTATUS OF THE EDUGATE PROJECTGATE ACTIVITIES @ WUPPERTAL

n working on novel PET detector for a new UHF MRI compatible BrainPET insert

n multiple simulation studies, with and without optical photons

n HPC system JURECA: simulations with high statisticsà normalisation and phantoms inside new scanner geometries

example: hot rod phantom

normalisation: 10,000 core-hours

phantom (ø 20cm): 7,200 core-hours

reconstruction with in-house software PRESTO

Further Activities à Mirjam Lenz (PhD student)

Page 9: Status of the EduGATE Project - IN2P3 Events Directory ... · nworking on novel PET detector for a new UHF MRI compatible BrainPET insert nmultiple simulation studies, with and without

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PROF. DR. UWE PIETRZYKSTATUS OF THE EDUGATE PROJECT

GATE ACTIVITIES @ WUPPERTAL

n difficulty with optical photons:

– DAVIS model not yet available for used crystal + reflector

combination in crystal arrays

– UNIFIED model possible, but requires careful estimation of many

parameters

– multilayer geometries require HPC system

n validated digitiser for Philips Digital Photon Counting (dSiPMs)

– running on HPC system JURECA

à generalisation of the module along with digitiser for analogue

SiPMs?

Further Activities à Mirjam Lenz (PhD student)

Page 10: Status of the EduGATE Project - IN2P3 Events Directory ... · nworking on novel PET detector for a new UHF MRI compatible BrainPET insert nmultiple simulation studies, with and without

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PROF. DR. UWE PIETRZYKSTATUS OF THE EDUGATE PROJECTGATE ACTIVITIES @ WUPPERTAL

Prof. Dr. Uwe Pietrzyk

School of Mathematics and Natural Sciences

– Medical Physics –

Bergische Universität Wuppertal

http://www.medizinphysik.uni-wuppertal.de

[email protected]

[email protected]

Contact