Stent Redesign

Whit Miller

BME Senior Design

Spring 2001

Market Analysis

• In 1999, US Physicians performed over 500,000 PCTA

procedures involving

a stent placement

• Within one year of de-

ployment, 50% of stents illicit a restenosis.

Making a Better Mousetrap

• Current stents are bare metal

• A covered stent would have at least two advantages

• Limit SMC proliferation at the deployment site

• Expedite endothelialization

SES Vs Balloon-Deployed

• Self-Expanding Stents are considered superior for two reasons

• Maximize deployment precision

• Minimize catheterization time

Current Technology

• Best of the Current Covered SESs

• The Wallgraft and Corvita

The need for improvement

• Current covered SES have limited proven ability to prevent restenosis

• Neurovascular interventionalists have limited options for cerebral stenting

Project Goals

• Select a stent covering

• Covering will be mated with superior stent design

• Investigate commercial polymers and cadaveric decellularlized material

• Subject covering to filtration, deployment constraints