Upload
others
View
5
Download
0
Embed Size (px)
Citation preview
Supplemental information A
Potential of hyphenated ultra-high performance liquid
chromatography-scheduled multiple reaction monitoring algorithm
for large-scale quantitative analysis of traditional Chinese medicines
Qingqing Song,a,b,# Yuelin Song,a,#,* Na Zhang,a,b Jun Li,a Yong Jiang,c Kerong Zhang,d Qian
Zhang,a and Pengfei Tu a*
a Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese
Medicine, Beijing 100029, China;b School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102,
China;c State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences,
Peking University, Beijing 100191, China;d Application Support Center, AB SCIEX, Shanghai 200233, China.
# These two authors contribute equally to this article.
*Correspondence to:
Dr. Yuelin Song, E-mail address: [email protected], Tel./fax: +86-10-64286100
Prof. Pengfei Tu, E-mail address: [email protected], Tel./fax: +86-10-82802750.
Figure legends
Fig. S1 Overlaid extracted ion current (EIC) chromatograms of all 70 ion transitions
monitored under positive polarity and all for 196 ion transitions monitored under negative
polarity for eight raw materials, including Ginseng Radix, Aconiti Lateralis Radix
Praeparata, Solani Melongenae Radix, Pheretima, Galli Gigerii Endothelium Corneum,
Cistanches Herba, Polygalae Radix, and Draconis Resina.
Electronic Supplementary Material (ESI) for RSC Advances.This journal is © The Royal Society of Chemistry 2015
4 8 12 16 20 24 28 32Time, min
0.0
2.0e6
4.0e6
6.0e6
8.0e6Intensity, cps
Ginseng Radix in positive polarity
Ginseng Radix in negative polarity
4 8 12 16 20 24 28 32Time, min
0.0
2.0e6
4.0e6
6.0e6
8.0e6
1.0e7
Intensity, cps
4 8 12 16 20 24 28 32Time, min
0.0
2.0e6
4.0e6
6.0e6
8.0e6
1.0e7Intensity, cps
4 8 12 16 20 24 28 32Time, min
0.0
2.0e6
4.0e6
6.0e6
8.0e6
1.0e7
Intensity, cps
Aconiti Lateralis Radix Praeparata in positive polarity
Aconiti Lateralis Radix Praeparata in negative polarity
4 8 12 16 20 24 28 32Time, min
0.0
2.0e6
4.0e6
6.0e6
8.0e6Intensity, cps
4 8 12 16 20 24 28 32Time, min
0.0
2.0e6
4.0e6
6.0e6
8.0e6
Intensity, cps
Solani Melongenae Radix in positive polarity
Solani Melongenae Radix in negative polarity
4 8 12 16 20 24 28 32Time, min
0.0
2.0e6
4.0e6
6.0e6
8.0e6
1.0e7
Intensity, cps
4 8 12 16 20 24 28 32Time, min
0.0
8.0e5
1.6e6
2.4e6
Intensity, cps
Pheretima in positive polarity
Pheretima in negative polarity
4 8 12 16 20 24 28 32Time, min
0.0
2.0e6
4.0e6
6.0e6
8.0e6
1.0e7
Intensity, cps
4 8 12 16 20 24 28 32Time, min
0.0
8.0e4
1.6e5
2.4e5Intensity, cps
Galli Gigerii Endothelium Corneum in positive polarity
Galli Gigerii Endothelium Corneum in negative polarity
4 8 12 16 20 24 28 32Time, min
0.0
2.0e6
4.0e6
6.0e6
8.0e6
1.0e7Intensity, cps
4 8 12 16 20 24 28 32Time, min
0.0
2.0e6
4.0e6
6.0e6
8.0e6
1.0e7
Intensity, cps
Cistanches Herba in positive polarity
Cistanches Herba in negative polarity
4 8 12 16 20 24 28 32Time, min
0.0
2.0e6
4.0e6
6.0e6Intensity, cps
4 8 12 16 20 24 28 32Time, min
0.0
2.0e6
4.0e6
6.0e6
8.0e6
Intensity, cps
Polygalae Radix in positive polarity
Polygalae Radix in negative polarity