2006

Nucleic acidsU 0700 Synthesis and anti-HIV Activity of Novel Phenyl Branched Cyclopropyl Nucleo-

sides. — A series of novel cyclopropyl nucleosides such as (VIII) (8 examples) is syn-thesized and evaluated for antitumor and antiviral activities. Compound (VIII) and its cis-adenine analogue exhibit potent anti-HIV activities, but these inhibitory effects are associated with non-specific cyctotoxicity to MT-4 cells. — (WU, Y.; HONG*, J. H.; Farmaco 60 (2005) 9, 739-744; Coll. Pharm., Chosun Univ., Kwangju 501-759,S. Korea; Eng.) — R. Staver

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