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Table of TCGA Cancer Codes TCGA code
Cancer type Number*
ACC Adrenocortical carcinoma 90 BLCA Bladder urothelial carcinoma 396 BRCA Breast invasive carcinoma 988 CESC Cervical squamous cell carcinoma and endocervical
adenocarcinoma 194
CHOL Cholangiocarcinoma (bile duct) 35 COAD Colon adenocarcinoma 367 DLBC Lymphoid neoplasm diffuse large B−cell lymphoma 48 ESCA Esophageal carcinoma 185 GBM Glioblastoma multiforme 290 HNSC Head and neck squamous cell carcinoma 513 KICH Kidney chromophobe 66 KIRC Kidney renal clear cell carcinoma 451 KIRP Kidney renal papillary cell carcinoma 282 LAML Acute myeloid leukemia 197 LGG Brain lower grade glioma 533 LIHC Liver hepatocellular carcinoma 373 LUAD Lung adenocarcinoma 546 LUSC Lung squamous cell carcinoma 178 OV Ovarian serous cystadenocarcinoma 469 PAAD Pancreatic adenocarcinoma 185 PCPG Pheochromocytoma and paraganglioma (adrenal gland) 184 PRAD Prostate adenocarcinoma 499 READ Rectum adenocarcinoma 122 SARC Sarcoma 247 SKCM Skin cutaneous melanoma 371 STAD Stomach adenocarcinoma 395 TGCT Testicular germ cell tumors 155 THCA Thyroid carcinoma 504 THYM Thymoma 123 UCEC Uterine corpus endometrial carcinoma 248 UCS Uterine carcinosarcoma 57 UVM Uveal melanoma 8 *Number of samples with mutation data
HM
TEV
168f
s
R27
3C
T125
T
E56
*
Y23
4C
C27
5S
R33
5fs
E33
9fs
R33
7H
V17
3L
K13
2N
E33
9*
C13
5Y
ER
CS
D18
0del
P27
fs
R21
3*
V73
fs
TP53 mutant alleles in adrenocortical carcinoma (N=90)0.
00.
20.
40.
60.
81.
0
NbrSamples=90 Mutant Samples=18 Total Mutations=17
HM
TEV
168
R27
3
T125
E56
Y23
4
C27
5
R33
5
R33
7
V17
3
K13
2
C13
5
ER
CS
D18
0del
P27
R21
3
V73
E33
9
TP53 mutant positions in adrenocortical carcinoma (N=90) 0.
00.
51.
01.
52.
0
NbrSamples=90 Mutant Samples=18 Total Mutations=17
D25
9VA
161T
C12
4fs
G24
5VH
214R
E28
7*L2
57Q
R15
8HE
271Q
E29
4*R
175H
A15
9VR
282W
R28
0KK
132N
E33
6*R
248W
Q19
2*R
273C
S24
1FE
271K
Q33
1*R
280T
E28
5KR
248Q
TP53 mutant alleles in bladder urothelial carcinoma (N=396), top 25 0
510
15
NbrSamples=396 Mutant Samples=198 Total Mutations=226(115 not shown)
G24
4H
214
L257
R15
8E
294
E20
4R
175
D25
9P
151
P27
8R
282
K13
2E
336
A15
9Q
192
A16
1E
287
S24
1G
245
Q33
1R
273
E27
1E
285
R28
0R
248
TP53 mutant positions in bladder urothelial carcinoma (N=396), top 250
510
1520
NbrSamples=396 Mutant Samples=198 Total Mutations=226 (88 not shown)
C23
8FQ
331*
G26
6EH
179R
C14
1YG
245D
R30
6*R
110f
sE
285K
V21
6MR
273C
R20
9fs
L194
RG
108f
sY
220C
S24
1fs
I195
TC
176F
R24
8WR
342*
H19
3RR
213*
R19
6*R
273H
R17
5H
TP53 mutant alleles in breast invasive carcinoma (N=988), top 250
510
15
NbrSamples=988 Mutant Samples=305 Total Mutations=288(158 not shown)
E28
5V
216
C13
5R
280
C23
8R
209
C14
1D
281
V17
3E
286
G10
8K
132
I195
H17
9L1
94S
241
R24
8C
176
R21
3Y
220
R19
6R
342
H19
3R
273
R17
5
TP53 mutant positions in breast invasive carcinoma (N=988), top 250
510
15
NbrSamples=988 Mutant Samples=305 Total Mutations=288 (128 not shown)
S37
6C
S18
3*
R33
7H
K13
2N
E27
1K
L194
F
K31
9N
E28
7D
R28
0K
C23
8F
E28
5K
TP53 mutant alleles in cervical squamous cell carcinoma and endocervical adenocarcinoma (N=194)0.
00.
51.
01.
52.
0
NbrSamples=194 Mutant Samples=9 Total Mutations=12
S37
6
S18
3
R33
7
K13
2
E27
1
L194
K31
9
E28
7
R28
0
C23
8
E28
5
TP53 mutant positions in cervical squamous cell carcinoma and endocervical adenocarcinoma (N=194)0.
00.
51.
01.
52.
0
NbrSamples=194 Mutant Samples=9 Total Mutations=12
R24
8W
S24
1F
C14
1R
Y23
4fs
MC
NS
SC
M23
7fs
C12
4Y
TP53 mutant alleles in cholangiocarcinoma (N=35)0.
00.
20.
40.
60.
81.
0
NbrSamples=35 Mutant Samples=5 Total Mutations=6
R24
8
S24
1
C14
1
Y23
4
MC
NS
SC
M23
7
C12
4
TP53 mutant positions in cholangiocarcinoma (N=35)0.
00.
20.
40.
60.
81.
0
NbrSamples=35 Mutant Samples=5 Total Mutations=6
G18
7GG
266V
W91
*A
159P
S31
5PH
214R
D18
6GS
95P
Y22
0CC
135Y
R17
5CY
205C
S22
7PR
342*
R30
6*G
245S
T125
TR
196*
R27
3CR
273H
R21
3*R
248W
R24
8QR
282W
R17
5H
TP53 mutant alleles in colon adenocarcinoma (N=367), top 250
510
1520
25
NbrSamples=367 Mutant Samples=233 Total Mutations=328(193 not shown)
A15
9P
278
S22
7R
158
R33
7R
342
G26
6F1
13E
349
R26
7C
135
M23
7F1
09R
306
C17
6G
244
K13
2R
196
G24
5T1
25R
282
R21
3R
273
R24
8R
175
TP53 mutant positions in colon adenocarcinoma (N=367), top 250
510
1520
25
NbrSamples=367 Mutant Samples=233 Total Mutations=328 (162 not shown)
H19
3RF1
09S
V27
4LC
176F
P12
8fs
C27
5FE
198*
G24
5SI2
55de
lR
175G
E29
4*P
278A
V27
2MR
196*
R30
6*R
342*
C13
5FR
213*
R28
2WY
220C
R27
3CR
273H
R24
8WR
248Q
R17
5H
TP53 mutant alleles in esophageal carcinoma (N=185), top 250
24
68
NbrSamples=185 Mutant Samples=153 Total Mutations=164(82 not shown)
E19
8S
241
I255
del
V27
4R
110
H17
9R
158
E29
4C
229
I195
V27
2R
196
C17
6C
275
R30
6G
245
R34
2R
213
P27
8R
282
Y22
0C
135
R17
5R
273
R24
8
TP53 mutant positions in esophageal carcinoma (N=185), top 250
24
68
1012
14
NbrSamples=185 Mutant Samples=153 Total Mutations=164 (63 not shown)
M24
6RR
213Q
R24
9TP
152S
R34
2*R
156C
G24
4SQ
375K
A13
8TR
248L
V21
6MH
179R
T155
NC
238F
C23
8YY
234C
R15
8HG
245S
Y22
0CR
248W
R19
6*R
282W
R27
3HR
175H
R24
8Q
TP53 mutant alleles in glioblastoma multiforme (N=290), top 250
12
34
56
NbrSamples=290 Mutant Samples=84 Total Mutations=96(40 not shown)
R21
3P
152
R34
2R
156
G24
4Q
375
A13
8V
216
G26
6I1
95T1
55L1
30Y
234
R24
9R
158
G24
5D
281
Y22
0H
179
R19
6R
282
C23
8R
273
R17
5R
248
TP53 mutant positions in glioblastoma multiforme (N=290), top 250
24
68
10
NbrSamples=290 Mutant Samples=84 Total Mutations=96 (29 not shown)
R28
3PR
249S
G26
6EQ
192*
Y23
6CR
337C
R11
0LH
193L
T125
TV
157F
H17
9RP
278S
Y16
3CR
273C
E29
8*R
306*
R19
6*Y
220C
G24
5SR
248W
R27
3HR
213*
R28
2WR
175H
R24
8Q
TP53 mutant alleles in head and neck squamous cell carcinoma (N=513), top 250
24
68
1012
NbrSamples=513 Mutant Samples=367 Total Mutations=412(257 not shown)
Y23
6V
173
C17
6R
337
R28
3P
278
R11
0T1
25R
280
E29
8V
157
Q33
1R
306
G26
6Y
163
Y22
0H
193
R19
6R
282
R17
5R
213
H17
9G
245
R27
3R
248
TP53 mutant positions in head and neck squamous cell carcinoma (N=513), top 250
510
1520
NbrSamples=513 Mutant Samples=367 Total Mutations=412 (208 not shown)
Y22
0CP
190L
C22
9*Y
205C
T125
TA
159P
S24
1FC
275Y
R28
2WK
292*
H17
8QN
239D
R33
7HC
176F
R19
6*C
141W
F338
IR
267W
P25
0LP
27fs
M24
6IH
214L
R21
3*
TP53 mutant alleles in kidney chromophobe (N=66)0.
00.
51.
01.
52.
02.
53.
0
NbrSamples=66 Mutant Samples=22 Total Mutations=25
Y22
0P
190
C22
9Y
205
T125
A15
9S
241
C27
5R
282
K29
2H
178
N23
9R
337
C17
6R
196
C14
1F3
38R
267
P25
0P
27M
246
H21
4R
213
TP53 mutant positions in kidney chromophobe (N=66)0.
00.
51.
01.
52.
02.
53.
0
NbrSamples=66 Mutant Samples=22 Total Mutations=25
G24
5D
H17
8fs
R21
3Q
R21
3*
H19
3Y
K35
1N
D28
1Y
N23
9S
S24
1C
V27
2M
S36
2fs
V73
fs
TP53 mutant alleles in kidney renal clear cell carcinoma (N=451)0.
00.
51.
01.
52.
02.
53.
0
NbrSamples=451 Mutant Samples=15 Total Mutations=15
G24
5
H17
8
H19
3
K35
1
D28
1
N23
9
S24
1
V27
2
S36
2
R21
3
V73
TP53 mutant positions in kidney renal clear cell carcinoma (N=451)0.
00.
51.
01.
52.
02.
53.
0
NbrSamples=451 Mutant Samples=15 Total Mutations=15
L111
P
I255
del
S24
1C
H19
3P
W91
*
Y22
0S
R34
2L
TP53 mutant alleles in kidney renal papillary cell carcinoma (N=282)0.
00.
20.
40.
60.
81.
0
NbrSamples=282 Mutant Samples=7 Total Mutations=7
L111
I255
del
S24
1
H19
3
W91
Y22
0
R34
2
TP53 mutant positions in kidney renal papillary cell carcinoma (N=282)0.
00.
20.
40.
60.
81.
0
NbrSamples=282 Mutant Samples=7 Total Mutations=7
C17
6Y
P22
3fs
R28
0G
T125
T
M40
fs
S21
5G
V17
3fs
H19
3Y
R33
7C
Q31
7*
C14
1W
R24
8Q
H17
9R
R34
2fs
I195
S
R27
3C
E28
6G
TP53 mutant alleles in acute myeloid leukemia (N=197)0.
00.
20.
40.
60.
81.
0
NbrSamples=197 Mutant Samples=16 Total Mutations=17
C17
6
P22
3
R28
0
T125
M40
S21
5
V17
3
H19
3
R33
7
Q31
7
C14
1
R24
8
H17
9
R34
2
I195
R27
3
E28
6
TP53 mutant positions in acute myeloid leukemia (N=197)0.
00.
20.
40.
60.
81.
0
NbrSamples=197 Mutant Samples=16 Total Mutations=17
F212
fsR
158G
C17
6FV
173A
C17
6YV
173M
W14
6*M
237I
M24
6VY
236C
S21
5GR
306*
R21
3*R
273L
F109
VR
196*
G24
5SR
282W
R24
8WH
179R
R17
5HR
248Q
Y22
0CR
273H
R27
3C
TP53 mutant alleles in brain lower grade glioma (N=533), top 250
1020
3040
5060
NbrSamples=533 Mutant Samples=264 Total Mutations=326(158 not shown)
V21
6S
215
I195
Q13
6Y
163
C27
7R
306
P15
2C
275
H19
3M
237
R26
7C
176
R21
3F1
09R
158
R28
2V
173
R19
6G
245
H17
9Y
220
R17
5R
248
R27
3
TP53 mutant positions in brain lower grade glioma (N=533), top 250
1020
3040
5060
70
NbrSamples=533 Mutant Samples=264 Total Mutations=326 (119 not shown)
G26
2fs
C27
5RR
156P
A27
6fs
K29
2*E
258K
V19
7LR
174W
C27
5YS
215I
E20
4*I3
32F
Y20
5SR
280K
Q19
2*N
263f
sC
277*
A16
1SR
158H
Y22
0CY
205C
V15
7FR
248Q
H19
3RR
249S
TP53 mutant alleles in liver hepatocellular carcinoma (N=373), top 250
24
68
10
NbrSamples=373 Mutant Samples=115 Total Mutations=109(60 not shown)
E25
8V
197
R17
4I3
32R
280
R21
3M
237
A27
6G
266
Q19
2N
263
C27
7Y
126
A16
1R
158
Y22
0E
204
V14
3S
215
C27
5Y
205
R24
8V
157
H19
3R
249
TP53 mutant positions in liver hepatocellular carcinoma (N=373), top 250
24
68
10
NbrSamples=373 Mutant Samples=115 Total Mutations=109 (48 not shown)
P15
2LY
205C
R17
5HR
196*
G15
4VE
198*
C27
5FY
220C
M23
7IR
337L
E29
8*V
157F
Q31
7*E
343*
Q19
2*R
248L
C24
2FR
249M
R11
0LR
213*
A15
9PG
245V
R15
8LR
273L
T125
T
TP53 mutant alleles in lung adenocarcinoma (N=546), top 250
24
68
NbrSamples=546 Mutant Samples=296 Total Mutations=290(200 not shown)
Q31
7E
343
Y23
6Q
192
C24
2G
154
R11
0R
213
Q33
1Q
144
Y16
3Y
205
R28
0A
159
E28
6H
193
V15
7R
248
D28
1R
337
T125
G24
5R
158
R27
3R
249
TP53 mutant positions in lung adenocarcinoma (N=546), top 250
24
68
10
NbrSamples=546 Mutant Samples=296 Total Mutations=290 (161 not shown)
R15
8GR
158f
sP
278R
C13
5WR
283P
H17
9LY
234C
E27
1KY
220C
R30
6*H
214R
E22
4EH
193L
R33
7LR
267P
G24
5VC
242F
E29
8*R
273L
T125
TY
163C
V15
7FR
175G
R21
3*R
158L
TP53 mutant alleles in lung squamous cell carcinoma (N=178), top 250
12
34
5
NbrSamples=178 Mutant Samples=145 Total Mutations=140(84 not shown)
R30
6H
214
L111
R33
7G
154
G24
4R
267
C24
2E
298
Y16
3V
157
Y23
4E
271
E22
4R
249
R17
5R
213
T125
R24
8P
278
H19
3G
245
H17
9R
273
R15
8
TP53 mutant positions in lung squamous cell carcinoma (N=178), top 250
24
68
NbrSamples=178 Mutant Samples=145 Total Mutations=140 (55 not shown)
V27
2MR
342*
R21
3*H
193Y
C27
5YR
196*
V21
6MC
176F
L194
RG
245S
H17
9RS
241F
H19
3RY
163C
G24
5DC
176Y
R28
2WR
248W
V15
7FR
273C
R24
8QY
220C
I195
TR
273H
R17
5H
TP53 mutant alleles in ovarian serous cystadenocarcinoma (N=469), top 250
24
68
1012
14
NbrSamples=469 Mutant Samples=391 Total Mutations=355(208 not shown)
V21
6M
237
V27
2R
342
C27
5D
281
C23
8G
266
Y23
4P
278
G24
4K
132
V15
7H
179
S24
1R
282
H19
3Y
163
Y22
0C
176
I195
G24
5R
175
R24
8R
273
TP53 mutant positions in ovarian serous cystadenocarcinoma (N=469), top 250
510
1520
NbrSamples=469 Mutant Samples=391 Total Mutations=355 (150 not shown)
R33
7CC
124f
sQ
52fs
T123
fsV
274F
R30
6*L1
94H
E28
6*C
176G
D18
6fs
G15
4VV
157F
N23
9DY
220C
H17
9YH
179R
R27
3HG
245S
R27
3CR
213*
R19
6*R
282W
R24
8QR
248W
R17
5H
TP53 mutant alleles in pancreatic adenocarcinoma (N=185), top 250
12
34
56
NbrSamples=185 Mutant Samples=120 Total Mutations=117(64 not shown)
T123
V27
4R
306
L194
E28
6C
176
D18
6G
154
V15
7N
239
G26
6Y
220
Y20
5P
151
C13
5C
124
S24
1R
213
R19
6H
179
G24
5R
282
R17
5R
273
R24
8
TP53 mutant positions in pancreatic adenocarcinoma (N=185), top 250
24
68
10
NbrSamples=185 Mutant Samples=120 Total Mutations=117 (50 not shown)
E27
1VA
PAP
SW
PL8
6fs
V17
3MA
74T
P82
LT2
56I
C13
5YQ
165f
sM
237I
H19
3NP
177R
R34
2*R
248W
R27
3CE
298*
VQ
L143
fsR
175H
R28
2WR
209f
sC
141G
Y16
3HG
245D
N23
9DG
245S
R24
8Q
TP53 mutant alleles in prostate adenocarcinoma (N=499), top 250
12
34
NbrSamples=499 Mutant Samples=61 Total Mutations=59(18 not shown)
C12
4R
181
E27
1A
PAP
SW
PL8
6V
173
A74
P82
T256
Q16
5M
237
P17
7R
342
R27
3E
298
VQ
L143
R17
5R
282
H19
3R
209
C14
1C
135
Y16
3N
239
R24
8G
245
TP53 mutant positions in prostate adenocarcinoma (N=499), top 250
12
34
56
7
NbrSamples=499 Mutant Samples=61 Total Mutations=59 (13 not shown)
P15
1SY
220F
GFR
LG10
8fs
C23
8YE
287*
Q13
6*R
337S
S95
PK
120E
C27
5YR
196*
G26
6VP
278T
V27
2GM
246V
E51
*G
245S
R30
6*R
213*
R27
3CR
248Q
R24
8WR
273H
R28
2WR
175H
TP53 mutant alleles in rectum adenocarcinoma (N=122), top 250
24
68
10
NbrSamples=122 Mutant Samples=91 Total Mutations=105(46 not shown)
E28
7Q
136
R33
7S
95K
120
C27
5R
196
G26
6V
272
M24
6E
51I2
51I1
95L1
94E
258
E28
6P
278
R30
6P
151
R21
3G
245
R28
2R
248
R17
5R
273
TP53 mutant positions in rectum adenocarcinoma (N=122), top 250
24
68
10
NbrSamples=122 Mutant Samples=91 Total Mutations=105 (36 not shown)
Y22
0CC
242S
E28
6KE
298*
Y22
0HC
275f
sY
163N
S24
1FH
179Q
D25
9VK
132E
G33
4fs
R24
8QF1
13de
lN
268Y
N26
8fs
AK
SV
TCT1
19de
lW
91*
C27
5YG
244S
R21
3*M
237I
C23
8YR
248W
R17
5H
TP53 mutant alleles in sarcoma (N=247), top 250
12
34
NbrSamples=247 Mutant Samples=85 Total Mutations=78(42 not shown)
F212
D28
1V
272
A18
9C
242
E28
6E
298
Y16
3S
241
D25
9K
132
G33
4F1
13de
lA
KS
VTC
T119
del
W91
G24
4M
237
C23
8H
179
N26
8C
275
R21
3Y
220
R24
8R
175
TP53 mutant positions in sarcoma (N=247), top 250
12
34
5
NbrSamples=247 Mutant Samples=85 Total Mutations=78 (34 not shown)
P15
1SP
151L
R21
3QD
48N
Y22
0CS
96fs
A27
6fs
P19
1LP
152L
P27
8SS
127F
R29
0CA
159V
H17
9YE
286K
P17
7LR
280K
R24
8WR
342*
F134
LP
27S
R19
6*Q
317*
S24
1FR
213*
TP53 mutant alleles in skin cutaneous melanoma (N=371), top 250
12
34
NbrSamples=371 Mutant Samples=56 Total Mutations=57(16 not shown)
G26
6D
48Y
220
S96
A27
6P
191
P15
2S
127
R29
0A
159
H17
9E
286
P17
7R
280
R24
8R
342
V14
3F1
34P
278
P15
1P
27R
196
Q31
7S
241
R21
3
TP53 mutant positions in skin cutaneous melanoma (N=371), top 250
12
34
5
NbrSamples=371 Mutant Samples=56 Total Mutations=57 (12 not shown)
G24
5SR
342*
R33
7CR
158H
P15
1TH
179R
R24
9SS
241f
sF2
70L
P34
fsV
173M
R19
6*E
286K
C17
6FV
272M
P15
3fs
M23
7IR
248W
Y22
0CR
213*
R24
8QR
282W
R27
3HR
273C
R17
5H
TP53 mutant alleles in stomach adenocarcinoma (N=395), top 250
24
68
10
NbrSamples=395 Mutant Samples=190 Total Mutations=190(94 not shown)
Y20
5R
249
S24
1T1
25P
34G
245
R19
6L1
30F2
70R
342
I195
V27
2P
72P
153
M23
7V
173
E28
6Y
220
H17
9R
213
C17
6R
282
R24
8R
175
R27
3
TP53 mutant positions in stomach adenocarcinoma (N=395), top 250
510
1520
NbrSamples=395 Mutant Samples=190 Total Mutations=190 (75 not shown)
C14
1YN
239S
S24
1PR
213Q
Q16
7fs
H17
9RQ
144*
R24
9SM
237K
S24
1CP
278T
V17
3LD
61fs
W14
6*S
241F
R15
8CS
240G
R17
5HG
244S
R21
3*Y
220C
R27
3CR
248Q
R27
3HR
248W
TP53 mutant alleles in uterine corpus endometrial carcinoma (N=248), top 250
12
34
5
NbrSamples=248 Mutant Samples=69 Total Mutations=73(28 not shown)
R28
2L2
52de
lD
281
C14
1Q
167
H17
9Q
144
M23
7V
173
D61
W14
6H
193
R15
8S
240
R17
5P
278
R24
9G
244
C23
8N
239
Y22
0R
213
S24
1R
273
R24
8
TP53 mutant positions in uterine corpus endometrial carcinoma (N=248), top 250
24
68
NbrSamples=248 Mutant Samples=69 Total Mutations=73 (16 not shown)
S18
3*V
216L
S12
1fs
R24
8WQ
100*
R28
0TR
273C
K13
2NE
349*
Y20
5NC
176f
sG
266V
I195
TR
249S
G24
5DR
181C
R21
3*H
193Y
C24
2SR
175H
H17
9RH
193R
S24
1YR
273H
R24
8Q
TP53 mutant alleles in uterine carcinosarcoma (N=57), top 250
12
34
56
NbrSamples=57 Mutant Samples=52 Total Mutations=52(15 not shown)
N23
9S
183
V21
6S
121
Q10
0R
280
K13
2E
349
Y20
5C
176
G26
6I1
95R
249
G24
5R
181
R21
3C
242
R17
5P
151
C23
8S
241
H17
9H
193
R27
3R
248
TP53 mutant positions in uterine carcinosarcoma (N=57), top 250
12
34
56
7
NbrSamples=57 Mutant Samples=52 Total Mutations=52 (9 not shown)
C17
6F
C23
8Y
G26
6V
V27
2M
V73
fs
W91
*
G24
5D
H19
3R
K13
2N
R30
6*
G24
5S
M23
7I
R34
2*
Y20
5C
H17
9R
R19
6*
R27
3H
R28
2W
R17
5H
T125
T
Y22
0C
R24
8Q
R21
3*
R24
8W
R27
3C
Number of cancer types where each TP53 mutation occurs, top 250
510
1520
1925 not shown
V17
3
C13
5
C14
1
I195
L194
M23
7
P15
1
C17
6
C27
5
H19
3
R28
2
R34
2
C23
8
G24
5
G26
6
H17
9
R33
7
S24
1
Y20
5
R17
5
T125
Y22
0
R21
3
R24
8
R27
3
Number of cancer types where each TP53 mutation position occurs, top 250
510
1520
1308 not shown
M23
7I
V27
2M
Y16
3C
S24
1F
E28
5K
R24
9S
I195
T
G24
5D
C17
6F
V15
7F
R34
2*
H19
3R
R30
6*
H17
9R
T125
T
G24
5S
R19
6*
Y22
0C
R21
3*
R28
2W
R24
8W
R27
3H
R24
8Q
R27
3C
R17
5H
Number of times each TP53 mutation occurs across all cancer types, top 250
2040
6080
100
120
2385 not shown
K13
2
E28
5
Y16
3
V15
7
C23
8
G26
6
R34
2
P27
8
I195
R24
9
R28
0
R15
8
T125
S24
1
C17
6
R19
6
H19
3
H17
9
Y22
0
R28
2
R21
3
G24
5
R17
5
R24
8
R27
3
Number of times each TP53 mutation position occurs across all cancer types, top 250
5010
015
020
0
1919 not shown
ACC
ACC
DLB
CLA
ML
LIH
CP
RA
DS
AR
CTH
YM
UC
SG
BM
LUS
CPA
AD
BLC
ALU
AD
UC
EC
RE
AD
ES
CA
BR
CA
HN
SC
CO
AD
STA
DO
VLG
G
Total number of TP53 R273 mutations in different cancer types0
1020
3040
5060
70
ACC
ACC
DLB
CLA
ML
LIH
CP
RA
DS
AR
CTH
YM
UC
SG
BM
LUS
CPA
AD
BLC
ALU
AD
UC
EC
RE
AD
ES
CA
BR
CA
HN
SC
CO
AD
STA
DO
VLG
G
Mutated allele breakdown for TP53 R273 mutations0
1020
3040
5060
70
R273CR273LR273SR273HR273P
ACC
ACC
DLB
CLA
ML
LIH
CP
RA
DS
AR
CTH
YM
UC
SG
BM
LUS
CPA
AD
BLC
ALU
AD
UC
EC
RE
AD
ES
CA
BR
CA
HN
SC
CO
AD
STA
DO
VLG
G All
0.0
0.2
0.4
0.6
0.8
1.0
Proportional view of allele breakdown of TP53 R273 mutations 1 1 1 1 1 1 1 1 4 5 6 6 8 9 9 10 11 15 15 17 20 23 76 242
R273CR273LR273SR273HR273P
CH
OL
DLB
CLA
ML
THY
MS
KC
MLI
HC
LUS
CS
AR
CLU
AD
PR
AD
BR
CA
UC
SR
EA
DU
CE
CG
BM
PAA
DS
TAD
ES
CA
LGG OV
CO
AD
HN
SC
BLC
A
Total number of TP53 R248 mutations in different cancer types0
510
1520
CH
OL
DLB
CLA
ML
THY
MS
KC
MLI
HC
LUS
CS
AR
CLU
AD
PR
AD
BR
CA
UC
SR
EA
DU
CE
CG
BM
PAA
DS
TAD
ES
CA
LGG OV
CO
AD
HN
SC
BLC
A
Mutated allele breakdown for TP53 R248 mutations0
510
1520
R248QR248PR248WR248GR248LR248fs
CH
OL
DLB
CLA
ML
THY
MS
KC
MLI
HC
LUS
CS
AR
CLU
AD
PR
AD
BR
CA
UC
SR
EA
DU
CE
CG
BM
PAA
DS
TAD
ES
CA
LGG OV
CO
AD
HN
SC
BLC
A All
0.0
0.2
0.4
0.6
0.8
1.0
Proportional view of allele breakdown of TP53 R248 mutations1 1 1 1 2 4 4 4 5 5 6 7 9 9 10 10 10 15 15 19 20 20 23 201
R248QR248PR248WR248GR248LR248fs
SK
CM
PR
AD
UC
EC
UC
S
BLC
A
LUA
D
LUS
C
GB
M
SA
RC
PAA
D
RE
AD
ES
CA
LGG
HN
SC
STA
D
OV
BR
CA
CO
AD
Total number of TP53 R175 mutations in different cancer types0
510
1520
25
SK
CM
PR
AD
UC
EC
UC
S
BLC
A
LUA
D
LUS
C
GB
M
SA
RC
PAA
D
RE
AD
ES
CA
LGG
HN
SC
STA
D
OV
BR
CA
CO
AD
Mutated allele breakdown for TP53 R175 mutations0
510
1520
25
R175HR175fsR175CR175GR175L
SK
CM
PR
AD
UC
EC
UC
S
BLC
A
LUA
D
LUS
C
GB
M
SA
RC
PAA
D
RE
AD
ES
CA
LGG
HN
SC
STA
D
OV
BR
CA
CO
AD All
0.0
0.2
0.4
0.6
0.8
1.0
Proportional view of allele breakdown of TP53 R175 mutations1 2 2 2 3 3 3 5 5 6 10 11 11 12 13 16 19 28 152
R175HR175fsR175CR175GR175L
KIR
C
LIH
C
UC
S
BR
CA
ES
CA
GB
M
RE
AD
STA
D
LUS
C
PAA
D
BLC
A
CO
AD
PR
AD
LGG
LUA
D
HN
SC
OV
Total number of TP53 G245 mutations in different cancer types0
24
68
1012
KIR
C
LIH
C
UC
S
BR
CA
ES
CA
GB
M
RE
AD
STA
D
LUS
C
PAA
D
BLC
A
CO
AD
PR
AD
LGG
LUA
D
HN
SC
OV
Mutated allele breakdown for TP53 G245 mutations0
24
68
1012
G245DG245SG245VG245CG245fsG245R
KIR
C
LIH
C
UC
S
BR
CA
ES
CA
GB
M
RE
AD
STA
D
LUS
C
PAA
D
BLC
A
CO
AD
PR
AD
LGG
LUA
D
HN
SC
OV All
Proportional view of allele breakdown of TP53 G245 mutations0.
00.
20.
40.
60.
81.
0 1 1 1 3 3 3 3 3 5 5 6 7 7 8 8 13 13 90
G245DG245SG245VG245CG245fsG245R
ACC
ACC
BLC
AG
BM
UC
SK
IRC
LIH
CK
ICH
OV
PAA
DR
EA
DS
AR
CU
CE
CE
SC
ALG
GLU
AD
LUS
CS
KC
MS
TAD
BR
CA
CO
AD
HN
SC
Total number of TP53 R213 mutations in different cancer types0
24
68
1012
ACC
ACC
BLC
AG
BM
UC
SK
IRC
LIH
CK
ICH
OV
PAA
DR
EA
DS
AR
CU
CE
CE
SC
ALG
GLU
AD
LUS
CS
KC
MS
TAD
BR
CA
CO
AD
HN
SC
Mutated allele breakdown for TP53 R213 mutations0
24
68
1012
R213*R213QR213LR213PR213G
ACC
ACC
BLC
AG
BM
UC
SK
IRC
LIH
CK
ICH
OV
PAA
DR
EA
DS
AR
CU
CE
CE
SC
ALG
GLU
AD
LUS
CS
KC
MS
TAD
BR
CA
CO
AD
HN
SC All
0.0
0.2
0.4
0.6
0.8
1.0
Proportional view of allele breakdown of TP53 R213 mutations1 1 1 1 1 2 2 3 3 3 3 3 3 4 4 4 4 5 5 7 11 12 83
R213*R213QR213LR213PR213G
CH
OL
ACC
ACC
.1D
LBC
LAM
LTH
YM
KIC
HK
IRC
LIH
CS
KC
MS
AR
CP
RA
DU
CS
LUS
CU
CE
CG
BM
LUA
DPA
AD
RE
AD
BLC
AE
SC
AB
RC
AS
TAD
HN
SC
OV
CO
AD
LGG
Positional breakdown of TP53 mutations across cancer types0
2040
6080
100
R273R248R175G245R213
CH
OL
ACC
ACC
.1D
LBC
LAM
LTH
YM
KIC
HK
IRC
LIH
CS
KC
MS
AR
CP
RA
DU
CS
LUS
CU
CE
CG
BM
LUA
DPA
AD
RE
AD
BLC
AE
SC
AB
RC
AS
TAD
HN
SC
OV
CO
AD
LGG All
Proportional position breakdown of TP53 mutations0.
00.
20.
40.
60.
81.
0 1 2 2 2 2 2 3 3 8 8 13 15 15 22 23 24 29 30 35 41 44 50 51 72 74 83 114
768