Tailored reagents and solutions for immuno-oncology · 2018. 1. 29. · 1. A partner throughout your immuno-oncology pipeline. From preclinical to clinical stages, maximize the potential

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Tailored reagents and solutions for immuno-oncologyA partner throughout your immuno-oncology pipeline

1

A partner throughout your immuno-oncology pipeline

From preclinical to clinical stages, maximize the potential of your immuno-oncology pipeline with the right tools and continuous support. We will work with you to identify the best antibody product for your needs, and provide it in the right format for your project – whether that’s a custom concentration or size, carrier free, dye conjugated, or a completely new custom antibody.

In addition, get support for your specific protocols with our extensive range of ancillary reagents for IHC, ELISA kits and antibody pairs, and multiplex assays.

Solutions for the immuno-oncology pipeline

Target investigation and characterization

Biomarkerdiscovery

Assaydevelopment

Assay validationand optimization

Diagnosticapplications

Comprehensive catalog for immunology research

– IHC-FFPE– Flow cytometry– ELISA– Reactivity in human, mouse, and non-human primates

Production scale-up

– cGMP scale-up– Multiple batches– Scalable production

Diagnostic assays

– Class I/CE antibodies– IVD commercialization

Reliable custom and multiplex options

– Custom formulation, concentration, and quantity– Conjugated primary antibodies– Carrier-free antibodies– Multiplex assays– ELISA kits and matched antibody pairs– Antibody panels– Custom antibody development

Consistency in supply

and quality

Flexible and tailored solutions

Easy production scale-up

Target investigation and characterization

Biomarkerdiscovery

Assaydevelopment

Assay validationand optimization

Diagnosticapplications

Comprehensive catalog for immunology research

– IHC-FFPE– Flow cytometry– ELISA– Reactivity in human, mouse, and non-human primates

Production scale-up

– cGMP scale-up– Multiple batches– Scalable production

Diagnostic assays

– Class I/CE antibodies– IVD commercialization

Reliable custom and multiplex options

– Custom formulation, concentration, and quantity– Conjugated primary antibodies– Carrier-free antibodies– Multiplex assays– ELISA kits and matched antibody pairs– Antibody panels– Custom antibody development

Consistency in supply

and quality

Flexible and tailored solutions

Easy production scale-up

Let’s talk

To find out more about how we can help with your immuno-oncology pipeline, contact us with your requirements.

[email protected]

2

Our ranges and services

Primary antibodies

A catalog of antibodies to the complete range of immuno-oncology targets. To ensure consistency of supply – and consistency across your results – we have an extensive range of recombinant rabbit monoclonal antibodies. All our antibodies are extensively validated in relevant applications, and we have an expanding selection of knockout-validated antibodies for confirmed specificity.

Tailored formulations

Recombinant rabbit monoclonal antibodies in the format you need. Our custom formulations services include carrier free, azide free, low endotoxin, custom concentrations, custom sizes.

Antibody conjugation

Custom conjugation of any of our recombinant antibodies to a range of dyes, including Alexa Fluor® dyes (405, 488, 555, 568, 594, 647, 680, 750, 790), FITC, biotin and HRP.

We also have conjugation kits available on our catalog, which allow you to quickly and efficiently label your antibody with various enzymatic and fluorescent dyes, including Cy® dye.

ELISA kits

ELISA kits and matched antibody pairs containing the same high-quality monoclonal antibodies that you will find on our catalog. Our ELISA kits are rigorously tested in complex biological samples to provide consistent and specific performance.

SimpleStep ELISA® kits use a simplified protocol that generates data in just 90 minutes, without compromising on performance.

Matched antibody pairs used in our SimpleStep ELISA assays are also available separately, allowing you to build and adapt your own ELISA kits.

Multiplex assays

Our FirePlex® platform allows multiplex detection of cytokine and miRNA analytes. The platform uses fluorescent encoding of hydrogel particles to enable detection of up to 75 protein analytes or 400 miRNAs directly from biofluids, and offers flexible and fully customizable panels for miRNA and cytokine quantification. Assay readout is performed on standard flow cytometers, with analysis using free integrated software.

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188 miRNAs in 154 publications

mir-155 mir-155 mir-155

mir-106bmir-29b mir-15

mir-150mir-106a

mir-24mir-124

mir-27mir-223 mir-106b

mir-7 mir-222

mir-23a mir-21-5p

mir-29a-3p

mir-142-3p

mir-21

mir-30amir-31

hsa-mir-155

mir-23bmir-101

mir-92a

mir-146b

mir-146amir-210

mir-92

mir-326

mir-17mir-10amir-19a

mir-20amir-182

mir-29b mir-141

mir-20b mir-126mir-155-5p

mir-181a

mir-10a

mir-7mir-222mir-221

mir-29mir-339

mir-182

mir-9

mir-124mir-181b

mir-34a

mir-23b

mir-203

mir-31

mir-17

mir-146

mir-30a

mir-150

mir-197

mir-191

mir-133bmir-29a

mir-146amir-181a mir-143

mir-34amir-142-3p

mir-499

mir-126mir-134

mir-132

mir-21

mir-338

mir-24

mir-223

mir-30b

mir-22

mir-145

mir-20a

mir-29mir-181amir-17

mir-181b

mir-21

mir-29cmir-124mir-142-3p

mir-29a

mir-126

mir-24mir-146a

mir-223mir-33

mir-19bmir-132mir-34a

mir-34c

mir-142mir-204

mir-92

mir-122

mir-142-5pmir-221mir-30a

mir-19amir-33a

mir-125amir-146b

mir-125bmir-210mir-223-3p

mir-9

mir-7

let-7b

let-7c

let-7a let-7

let-7e

127 miRNAs in 129 publications 152 miRNAs in 148 publications

T cellsDendritic cellsMacrophages

miRNAs associated with human macrophage, dendritic cell, and T cell characterization, generated using the FirePlex Discovery Engine that searches scientific literature to identify species-specific miRNAs for a given research area. Custom panels can be created to detect up to 400 miRNAs in a single assay.

Panel size and analyte lists for selected pre-designed multiplex immunoassay panels

Panel name abID Panel size Analyte list

Cytokine release syndrome panel

Custom panel* 9-plex IFNγ, IL-6, IL-8, IL-10, IL-6R, MCP1, MIP1α, MIP1β, GM-CSF

Th1/Th2 Panel ab229792 (human)ab213395 (mouse)

7-plex IL-2, IL-4, IL-5, IL-6, IL-10, TNFα, IFNγ

Key cytokine panel ab229971 (human)ab213397 (mouse)

17-plex (human)14-plex (mouse)

GM-CSF, IFNγ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-9, IL-10, IL-12 p70, IL-13, IL-17A, MCP1, MIP1α, MIP1β, TNFα

Inflammation panel ab229793 (human)ab213396 (mouse)

8-plex (human)7-plex (mouse)

IFNγ, IL-1β, IL-6, IL-8, IL-10, IL-12p70, TNFα, MCP1

Custom antibodies

If you can’t find the antibody you need on our catalog, our custom antibody service uses three advanced antibody discovery platforms – RabMAb® rabbit monoclonal platform, next-generation sequencing, and phage display – to deliver the antibody you need at speed. Contact us to discuss your requirements.

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Immuno-oncology product directory

The product directory outlines our catalog products for immuno-oncology research. We can provide custom formulations and conjugations for these products. Please contact us to discuss your requirements.

Contents

Immune checkpoint markers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5

Adoptive T cell markers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7

Immune cell characterization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8Natural killer cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8T cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9Macrophage cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .18Dendritic cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .20

Legend

Primaries Primary antibodies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P Recombinant monoclonal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . R Knockout validated . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .KO

Immunoassays ELISA kit. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .ELISA SimpleStep ELISA® kit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . SSE

Proteins Recombinant . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . R Active . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . A

5

Immune checkpoint markers

Target Primary ELISA Proteins

PD-1 P R ELISA SSE R A

PD-L1 P R KO ELISA SSE R A

PD-L2 P R R A

CD28 P ELISA R A

CD80 P R ELISA R A

CD86 P R ELISA R A

CTLA4 P R ELISA R A

ICOS P R R A

ICOS-L P R R A

B7H3 P R R A

B7H4 P R R A

CD28H P R

B7H5 P R R

BTLA P R A

HVEM P ELISA R A

CD40L P R ELISA SSE R A

CD40 P R ELISA SSE R A

OX40 P R ELISA R A

OX40L P R ELISA R A


CD137L P R R A

CD27 P R ELISA R A

CD70 P ELISA R A

TIM3 P R A

GAL9 P R ELISA R A

GITR P ELISA R A

GITRL P ELISA R A

LAG-3 P R ELISA R A

MHC-II P R R A

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Product highlight

10

1

0.11 10 100 1000

MCF7 cell lysate (µg/mL)

OD

450

nM

10

1

0.1

0.0110 100 1000

Human PD-L1(pg/mL)

OD

450

nM

116

0100 101 102 103 104

NCAM – Alexa Fluor® 488 (525/30 BP)

Co

un

ts

Anti-human PD-L1 antibody, clone 28-8

- Recombinant rabbit monoclonal antibody

- Optimized for IHC, flow cytometry and western blot

Stained using anti-PD-L1 [28-8] RabMAb® antibody (ab205921) on wild-type L2987 cells (left) and PD-L1 knockout line of L2987 (right) .

Product highlight

Anti-human PD-1 antibody, clone EPR4877(2)


- Optimized for IHC

Paraffin-embedded human tonsil section stained with anti-PD-1 antibody (ab137132) at 1/500 dilution .

Product highlight

10

1

0.11 10 100 1000


OD

450

nM

10

1

0.1

0.0110 100 1000

Human PD-L1(pg/mL)

OD

450

nM

116

0100 101 102 103 104


Co

un

ts

Human PD-L1 [28-8] ELISA kit

- Sensitivity: 2 .9 pg/mL - Range: 21 .9–1400 pg/mL

Human PD-L1 standard curve in cell extraction buffer . Background-subtracted data values (mean +/1 SD) are graphed .

7

Adoptive T cell markers


CD19 P R R A

IL12 P R ELISA R A

NKG2D P R

Mesothelin P R ELISA SSE R

VEGFR2 P R ELISA SSE R A

Product highlight

Anti-human CD19 antibody, clone EPR5906

- Rabbit monoclonal antibody - Optimized for IHC-P, ICC/IF and

western blot

Raji cells stained with anti-human CD19 antibody (ab134114) at 1/500 dilution .

Product highlight

Anti-human mesothelin antibody, clone EPR2685(2)


- Optimized for IHC-P, ICC/IF, IP and western blot

IHC analysis of paraffin-embedded human mesothelioma tissue stained with anti-human mesothelin antibody (ab134109) at 1/800 dilution .

8

Immune cell characterization

Natural killer cells

Markers


CD3 P R R

CD4 P R R A

CD8 alpha P R R

CD44 P R ELISA R

CD57 P R

CD94/NKG2 P R

CD160 P R R A

CD161/NK1.1 P R R

FcGamma RIII/ CD16

P R R

Integrin alpha 2/ CD49b

P R KO R

KIR family P

NCAM-1/CD56 P R ELISA R

NKG2D P R

NKp30 P R R A

NKp44 P R R

NKp46/NCR1 P R

NKp80/KLRF1 P R

TCR alpha/beta P R

Cytokines


GM-CSF P R ELISA SSE R A

IFN gamma P R ELISA SSE R A

IL-10 P R ELISA SSE R A

IL13 P R ELISA SSE R A

TNF alpha P R ELISA SSE R A

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Product highlight

10

1

0.11 10 100 1000


OD

450

nM

10

1

0.1

0.0110 100 1000

Human PD-L1(pg/mL)

OD

450

nM

116

0100 101 102 103 104


Co

un

ts

Anti-human NCAM antibody, clone EP2567Y


- Optimized for flow cytometry, IHC-P, ICC/IF, IP and western blot

Flow cytometry histogram of methanol- fixed SH-SY5Y cells stained with anti-human NCAM antibody (ab75813, red line) .

T cells

Cytotoxic T cells – markers


CD3 P R R

CD8 P R R A

TCR alpha/beta P R

LFA-1 P R

CXCR3 P R R

Fas Ligand P ELISA R A

Lamp-1/CD107a P R R

EOMES/TBR2 P R R

T-Bet/TBX21 P R R

Cytotoxic T cells – cytokines


Granzyme A P R R A

Granzyme B P R ELISA R A

Perforin P ELISA R


TNF beta P R ELISA R A


Granulysin P R

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Product highlight

Anti-human CD3 antibody, clone EP449E


- Optimized for IHC-P, flow cytometry, and western blot

IHC analysis of formaldehyde-fixed, paraffin-embedded normal human tonsil tissue sections stained with anti-human CD3 antibody (ab52959) .

Gamma delta T cells – markers


CD3 P R R

CD4 P R R A

CD8 alpha P R R

CD27L/TNFSF7 P R A

CD161 P R R

CXCR4 P R KO R

EDG-1/S1P1 P R R

IL18R alpha/IL-1 R5 P R

IL23R P R A

NKG2D P R

TCR gamma/delta P

Gamma delta T cells – cytokines


Granzyme A P R R A

Granzyme B P R ELISA R A

Perforin P ELISA R


IL17A P ELISA SSE R A



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Product highlight

Anti-human CXCR4 antibody, clone UMB2


- Optimized for IHC-P, ICC/IF and western blot

Immunofluorescence of Jurkat cells stained with anti-human CXCR4 antibody (ab124824) at 1/250 dilution, counter-stained with DAPI .

T follicular helper cells – markers


CD3 P R R

CD4 P R R A

CD28 P ELISA R

CD40L P R ELISA SSE R A

CD84/SLAMF5 P R R A

CD229/SLAMF3 P R

CXCR4 P R KO R

CXCR5 P R R

ICOS P R R A

IL6R alpha P ELISA SSE R A

IL21R P R A

NTB-A/SLAMF6 P R R A

OX40/CD134 P R R

PD-1 P R ELISA SSE R A

SLAM/CD150 P R R

Bcl6 P R R

BATF P R

c-MAF P R R

STAT3 P R ELISA SSE R

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T follicular helper cells – cytokines







IL17F P ELISA SSE R A

IL21 P R ELISA R A

Product highlight


- Rabbit monoclonal antibody - Optimized for IHC-P, flow cytometry,

ICC/IF and western blot

IHC analysis of human tonsil tissue stained with anti-human CD4 antibody (ab133616) at 1/100 dilution .

T helper type 1 cells – markers


CCR1 P

CCR5 P R

CD3 P R R

CD4 P R R A

CXCR3 P R R

IFN gamma R1 ELISA SSE

IFN gamma R2 P R

IL12R beta P R

IL18R alpha P R

IL27R alpha P R A

STAT1 P R ELISA R

STAT4 P R R

T-bet/TBX21 P R R

T helper type 1 cells – cytokines






TNF beta P R ELISA R A

Product highlight

10

1

0.11 10 100 1000


OD

450

nM

10

1

0.1

0.0110 100 1000

Human PD-L1(pg/mL)O

D 4

50n

M

116

0100 101 102 103 104

NCAM – Alexa Fluor® 488 (525/30 BP)C

ou

nts

Human interferon gamma receptor 1 ELISA kit

- Sensitivity: 140 pg/mL - Range: 0 .14–100 ng/mL

Titration of MCF7 cell lysate within the working range of the human IFN gamma R1 ELISA (ab173193) . Background subtracted data from triplicate measurements are plotted .



CCR4 P

CCR6 P

CD3 P R R

CD4 P R R A

IL1R 1 P R

IL6R alpha P ELISA SSE R A

IL21R P R A

IL23R P R A

TGFbeta RII P R ELISA R A

Batf P R

IRF4 P R R

ROR alpha P R

ROR gamma P R

13

14




IL17F P ELISA SSE R A

IL21 P R ELISA R A

IL22 P R ELISA R A



CCR3 P R

CCR4 P

CCR8 P R R

CD3 P R R

CD4 P R R A

CXCR4 P R KO R

CD119 ELISA SSE

IFN gamma R2 P R

IL4 R alpha R

L17BR/IL17RB P R

ST2/IL-1R4 ELISA

TSLPR P R R

GATA3 P R R

IRF4/MUM1 P R R

STAT5 P R ELISA SSE R

STAT6 P R ELISA R




IL5 P ELISA SSE R A

IL9 P R ELISA R A



IL21 P R ELISA R A

IL31 P ELISA R A

15

Product highlight

Anti-human STAT6 antibody, clone YE361


- Optimized for flow cytometry, IHC-P, ICC/IF and western blot

IHC analysis of paraffin-embedded human skin carcinoma tissue stained with anti-human STAT6 antibody (ab32520) at 1/100 dilution .



CCR4 P

CCR6 P

CCR10 P R

CD3 P R R

CD4 P R R A

IL6 R alpha P ELISA SSE R A

IL21R P R A

TGF beta RII P R ELISA R A

AHR P R R

Batf P R

STAT3 P R KO ELISA SSE R



CCL7 P ELISA SSE R

CCL15 P ELISA SSE R A



IL21 P R ELISA R A


IL26/AK155 P R R


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Product highlight

Anti-human CCR10 antibody

- Optimized for flow cytometry, IHC-P, IP, ICC/IF, ELISA and western blot

IHC analysis of paraffin-embedded human spleen tissue stained with anti-human CCR10 antibody (ab3904) at 1/250 dilution .



CD3 P R R

CD4 P R R A

IL4 R alpha R

L17BR/IL17RB P R

TGF Beta RII P R ELISA R A

IRF4 P R R

PU.1 P R R



IL9 P R ELISA R A


Product highlight Anti-human PU.1 antibody, clone EPR3158Y


- Optimized for flow cytometry, IHC-P and western blot

IHC analysis of paraffin-embedded human tonsil tissue stained with anti-human PU .1 antibody (ab76543) at 1/100 dilution .

Regulatory T cells – markers


CD73 P R R

CD3 P R R

CD4 P R R A

CD5 P R R A

CD39/ENTPD1 P R R

CTLA4 P R ELISA R A

Folate receptor 4 P

GITR P ELISA R

CD25 P R ELISA R A

CD103 P R R

LAG3 P R ELISA R

LAP

LRRC32/GARP P

OX40 P R R A

CD62L P ELISA SSE R

FOXP3 P R R

Product highlight

Anti-human FOXP3 antibody, clone 236A/E7

- Optimized for IHC-P, ICC/IF and western blot

IHC analysis of paraffin-embedded human tonsil tissue stained with anti-human FOXP3 antibody (ab20034) .

Regulatory T cells – cytokines


Galectin 1 P R ELISA R A


IL35 P R

TGF beta 1 P R ELISA R A

17

18

Macrophage cells

General markers of macrophages


CD11b P R R

CD68 P R R A

CD163 P R ELISA R

CD45 P R R A

CD64 P R R

F4/80 P R R

MerTK P R ELISA SSE R A

Product highlight

Anti-human CD11b antibody, clone EP1345Y


- Optimized for IHC-P, flow cytometry, ICC/IF, IP and western blot

IHC analysis of paraffin-embedded human tonsil tissue stained with anti-human CD11b antibody (ab52478) at 5 µg/mL .

Product highlight

Anti-mannose receptor antibody, clone EPR6828(B)


- Optimized for flow cytometry and ICC/IF

IF analysis of Molt-4 cells stained with anti-mannose receptor antibody (ab195192, red) at 1/250 dilution . Tubulin is stained in green and nuclear DNA labeled with DAPI .

19

M1 macrophages


TLR4 P R

NFkB P R KO ELISA SSE R A

TNF P R ELISA SSE R A

IL6 P ELISA SSE R A

IL12 P R ELISA R A

Mhem macrophages


LXR alpha P R R

LXR beta P R

HO-1 P R ELISA R

Mox macrophages


TLR2 P R ELISA R

NRF2 P R R

IL1 beta P R ELISA SSE R A

COX2 P R ELISA SSE R A

Hemoglobin-stimulated macrophages


CD206 P R R

CD163 P R ELISA R


Product highlight Anti-human CD163 antibody, clone EPR19518


- Optimized for IHC-P, IHC-Fr, IP and western blot

IHC analysis of paraffin-embedded human liver tissue stained with anti-human CD163 antibody (ab182422) at 1/500 dilution .

20

M2 macrophages


LXR alpha P R R



M4 macrophages


IL6 P ELISA SSE R A

TNF P R ELISA SSE R A

MMP7 P R ELISA R

CD68 P R R A

S100A8 P R ELISA R A

Dendritic cells

CD14 dendritic cells


CD163 P R ELISA R


CD11c P R R

CD209 P R R

FXIIIA P

CD24 P R KO R

CD26 P R ELISA R A

CD64 P R R A

CX3CR1 P R

Product highlight



- Optimized for IHC-P and western blot

IHC analysis of methanol-fixed K562 cells stained with anti-human CD14 antibody (ab133335) at 1/500 dilution . Nuclei were counterstained with DAPI (blue) .

21

CD141 myeloid dendritic cells




CD103 P R R

CLEC9 P R

XCR1 P

Necl2 P R A

TLR3 P ELISA R A

TLR8 P R

CXCL10 P R ELISA SSE R A


CD1C myeloid dendritic cells



CD11c P R R

CD206 P R R


CD1C P R R

CD13 P R KO R A

CD33 P R R A

CD172 P R

CD80 P R ELISA R A

CD83 P R R

CD86 P R ELISA R A


CCR7 P R R

CLEC7A P R

CLEC6A P R

DEC205 P R R



22

Inflammatory dendritic cells




CD1a P R R

CD206 P R R

SIRP alpha P R R

IL6 P ELISA SSE R A

IL23 P R ELISA R A

Langerhan dendritic cells


CD1a P R R

Langerin P R R

CD36 P R ELISA R A

Plasmacytoid dendritic cells


CD45RA P

CD2 P R R

CD7 P R R

CD123 P R

CD304 P R ELISA R A

TLR7 P R R

TLR9 P R R

ILT7 P R

Product highlight Anti-human CD7 antibody, clone EPR4242


- Optimized for IHC-P, ICC/IF, IP and western blot

IHC analysis of paraffin-embedded human tonsil tissue stained with anti-human CD7 antibody (ab109296) at 1/100 dilution .

23

SLAN dendritic cells


CD163 P R ELISA R




Documents

Tailored reagents and solutions for immuno-oncology · 2018. 1. 29. · 1. A partner throughout your immuno-oncology pipeline. From preclinical to clinical stages, maximize the potential