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Tamer Refaat, MD PhD MSCI DHM
NAME Tamer Refaat
CURRENT POSITION TITLE - Research Assistant Professor, Radiation Oncology
department, Northwestern University, Chicago, IL, USA
- Lecturer, Clinical Oncology Department, Faculty of Medicine, Alexandria University, Egypt
- Executive Director, International Students Exchange Office, Faculty of Medicine, Alexandria University
- Coordinator, Junior Arab Medical Association Against Cancer
Current Address: 676 N Saint Clair St., Suite 1820, Chicago, IL 60611, USA Cellular Phone: +1 312 646 8687 Email: [email protected] , [email protected] , [email protected]
EDUCATION/TRAINING
INSTITUTION AND LOCATION DEGREE (if applicable) YEAR(s) FIELD OF STUDY
Faculty of Medicine, Alexandria University, Egypt MD 2001 Medicine and Surgery
Faculty of Medicine, Alexandria University, Egypt Masters 2006 Radiation Oncology
Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, USA
Fellowship 2008 (June 27th – December 31st) Clinical Oncology
Oscar Lambret Comprehensive Cancer Center, Lille II University, France Fellowship
2009 (June 28th – December 31st) – October 2010
Radiation Oncology
Vienna Medical School, Austria Fellowship 2010 (February/March) Radiation Oncology
Faculty of Medicine, Alexandria University, Egypt Doctorate Degree (PhD) 2011 Clinical Oncology and
Nuclear Medicine
Arab Academy for Science and Technology Diploma (DHM) 2011 Hospital Management
Northwestern University, The Graduate School Masters (MSCI) 2012 Clinical Investigations
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A. Positions and Honors. List in chronological order
Ø June 2003-‐ May 2006: Resident in the Clinical Oncology Department, University of Alexandria. Ø February 2007 – April 2007: Demonstrator and instructor, Clinical Oncology and Nuclear Medicine
Department, Faculty of Medicine, University of Alexandria, Egypt. Ø April 2007 – April 2011: Assistant Lecturer and Researcher, Clinical Oncology and Nuclear Medicine
Department, Faculty of Medicine, University of Alexandria, Egypt Ø May 2011 – Present: Lecturer, clinical oncology department, Faculty of Medicine, Alexandria University Ø 27th June 2008 – 28th December 2008: Visiting fellow, Robert H. Lurie Cancer Center, Northwestern
Memorial Hospital, Northwestern University, Chicago, IL, USA Ø 15th July 2009 – 15th January 2010: Fellow, Oscar Lambert Cancer Center, Lille II University, France Ø January 10th 2010 -‐ Present: Executive Director, International Students Exchange Office, Faculty of
Medicine, Alexandria University. Ø March 2010: Visiting fellow, Radiation Oncology, Vienna Medical School Ø August 1st, 2010 – October 30th, 2010: Visiting fellow, Robert H. Lurie Cancer Center, Northwestern
Memorial Hospital, Northwestern University, Chicago, IL, USA Ø September 2011 – February 2013: Research Associate, Radiation Oncology department, Feinberg School
of Medicine, Northwestern University Ø March 2013 – Present: Research Assistant Professor, Radiation Oncology department, Feinberg School of
Medicine, Northwestern University Ø May 2011 – Present: Coordinator, Junior Arab Medical Association Against Cancer
Memberships:
Member of American Society of Clinical Oncology (ASCO) Member of European Society for Therapeutic Radiology and Oncology (ESTRO) Member of European Society of Medical Oncology (ESMO) Member of American Society for Therapeutic Radiology and Oncology (ASTRO) Member of International Gynecological Cancer Society (IGCS) Member of Egyptian Cancer Association (ECA) Member of South and East Mediterranean College of Oncology (SEMCO) Member of Arab Medical Association Against Cancer (AMAAC) Member of International Gynecologic Cancer Society (IGCS)
Reviewer:
PLoS ONE (Public Library of Science Journal) [USA] Alexandria Journal of Medicine [Egypt] Public Health Action Journal [WHO]
Undergraduates Positions:
I. International:
1. International Federation of Medical Students' Associations –IFMSA – Standing Committee on Public Health –SCOPH-‐ Fundraiser 1999-‐2000.
2. IFMSA Project Committee Coordinator on Projects 1999-‐2001. 3. IFMSA vice SCOPH Director 2000-‐2001. 4. IFMSA Respondent to Global Stop TB Partnership 2002-‐2003. 5. SCOPH seniors' Club Coordinator 2002-‐2003. 6. International Coordinator of IFMSA Anti TB Campaign 2003-‐2004. 7. Senior Advisor for SCOPH Projects 2003-‐2004 (How to write the proposal, projects running, sustainability
and evaluation.)
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8. President of Organizing Committee of the Eastern Mediterranean medical students' Regional Meeting held in WHO EMRO July 2005
9. President of the IFMSA General Assembly Organizing Committee August 2005 attended by 850 medical students from 93 countries.
II. National:
1. Egyptian Medical Students' Association –EMSA-‐ National Public Health Officer –NPO-‐ 1998-‐2002. 2. Director of Egypt Bid against Germany for hosting IFMSA GA.
III. Local:
1. Alexandria Students' Scientific Association –ASSA-‐ Board member 1995-‐1997. 2. ASSA Local Public Health Officer 1996-‐1999. 3. ASSA Head of Scientific Committee 1997-‐1998. 4. ASSA Treasurer and ASSA Executive Board Member 1998-‐1999. 5. ASSA President 2000-‐2002.
B. Selected peer-‐reviewed publications (manuscript and abstracts in chronological order):
I. Selected Publications:
1. Tamer Refaat, Mehee Choi, et al. Markov Model and Cost-‐effectiveness analysis of Bevacizumab in HER2-‐ negative metastatic breast cancer. Am J Clin Oncol 2013 February 5 doi: 10.1097/COC.0b013e31827e4e9a (ahead of print)
2. Tamer Refaat, William Small Jr., et al. Three-‐dimensional image guided pulsed dose rate brachytherapy boosting bulky cervical cancer. Radiotherapy and Oncology Vol. 103 Supplement 2, Pages S97-‐S98, 2012
3. T.O. Thomas, T. Refaat, M. Choi, et al. Brachial Plexus Dose Tolerance in Head-‐and-‐Neck Cancer Patients Treated With Sequential Intensity Modulated Radiation Therapy. Int J Radiat Oncol Biol Phys 84(3):S524, 2012
4. T. Refaat, W. Small, et al. Pulsed-‐dose-‐rate and Image Guided Brachytherapy: Outcomes and Comparison to ICRU 38 Reference Point. Int J Radiat Oncol Biol Phys 84(3):S428, 2012.
5. Tamer Refaat, Mehee Choi, et al. Cost-‐effectiveness analysis using a Markov model assessing the addition of bevacizumab to paclitaxel in HER2-‐negative metastatic breast cancer patients. Journal of Clinical Oncology, 2012 ASCO Annual Meeting Proceedings (Post-‐Meeting Edition). Vol 30, No 15_suppl (May 20 Supplement), 2012: 1069
6. Tamer Refaat, Amr Elsaid, Nashaat Lotfy, Krystyna Kiel, William Small Jr., Phillip Nickers, Eric Lartigau, Concomitant chemoradiotherapy with high dose rate brachytherapy as a definitive treatment modality for locally advanced cervical cancer, Alexandria Journal of Medicine, (2011) 47, 15–24
7. Kiel K, Refaat T., Navanandan N et al. Hyperthermia and radiation therapy for locally advanced or recurrent breast cancer, Journal of Clinical Oncology, 2009 ASCO Annual Meeting Proceedings (Post-‐Meeting Edition) 27 (15S) (May 20 Supplement), 2009: 631.
8. Khadragi I, Zahra O, Gowil A, Abdelzaher E, Refaat T, Preoperative chemo-‐radiotherapy followed by surgery compared to surgery alone in patients with stage II and III esophageal cancer. Bull. Alex. Fac. Med., 2008, 44; 3: 743-‐748.
9. S.A.Elomnem, Y.Rostom, T.Refaat, Obesity and Cancer, impact on Chemotherapy Tolerance in obese females with breast cancer, Bull. Alex. Fac. Med., 2006, 42; 2: 456-‐465.
10. Abd El-‐Aziz Belal, Azza Adel Ibrahim, Tamer M. Refaat, Impact Of Maintaining Adequate Hemoglobin Level On The Treatment Outcome Of Stage III Cervical Carcinoma A Prospective, Non randomized Study, Bulletin of Alexandria Faculty of Medicine, Dec. 2006, 42; 4: 583-‐587.
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II. Books:
1. Tamer Refaat, "Chemotherapy dose in obese breast cancer patients" (ISBN 978-‐3-‐659-‐30136-‐0) © LAP LAMBERT Academic Publishing is a trademark of: AV Akademikerverlag GmbH & Co. KG Heinrich-‐Böcking-‐Str. 6-‐8, 66121, Saarbrücken, Germany. November 12, 2012.
2. The Role of Medical Students' in Promoting Adolescent health (Joint IFMSA – WHO/EMRO Project) published by WHO (Document WHO-‐EM/WRH/044/E/02.05).
III. Chapters:
Eric D. Donnelly, Tamer M. Refaat, William Small Jr., Image Guided Treatment Planning and Therapy in Postoperative Gynecologic Malignancies, A.N. Viswanathan et al. (eds.) Gynecologic Radiation Therapy, DOI: 978-‐3-‐540-‐68958-‐4_7, ISBN: 978-‐3-‐540-‐68954-‐6 © Springer-‐Verlag Heidelberg 2011. http://www.springer.com/978-‐3-‐540-‐68954-‐6
IV. Selected abstracts accepted:
1. Late chemoradiation treatment-‐related swallow effects in head and neck cancer patients, Jeri Logemann, Alfred Rademaker, Mehee Choi, Barbara Pauloski, Tamer Refaat, et al. Dyspahgia Research Society (DRS) annual meeting, 2013 Seattle, Washington, USA.
2. Cost-‐effectiveness analysis using a Markov model assessing the addition of bevacizumab to paclitaxel in HER2-‐negative metastatic breast cancer patients, Tamer Refaat, Mehee Choi, Germaine Gaber, William Small Jr., Krystyna D. Kiel, American Society of Clinical Oncology –ASCO-‐ Annual meeting 2012, Chicago, IL, USA.
3. Pulsed Dose Rate and Image Guided Brachytherapy: Outcomes and Comparison to ICRU 38 reference point, Tamer Refaat, William Small, Nashaat Lotfy, Amr Elsaid, Eric Lartigau, Phillip Nickers, the 54th 2012 Annual Meeting scheduled on October 28 -‐ 31 in Boston, Massachusetts, USA.
4. Brachial Plexus Dose Tolerance in Head and Neck Cancer Patients Treated with Sequential Intensity Modulated Radiation Therapy, Tarita Thomas, Tamer Refaat, Mehee Choi, Ian Bacchus, V. Sathiaseelan, B. Mittal, the 54th 2012 Annual Meeting scheduled on October 28 -‐ 31 in Boston, Massachusetts, USA.
5. Three-‐dimensional image guided pulsed dose rate brachytherapy boosting bulky cervical cancer, T. Refaat, W. Small Jr, N. Lotfy, A. Elsaid, E. Lartigau, P. Nickers. Accepted as poster presentation in World Brachytherapy Congress held joint with ESTRO31 congress May 9th – 13th 2012, Barcelona, Spain.
6. Comparative evaluation of two methods of chemotherapy dose calculation according to body surface area and body mass index in obese females with breast cancer. T. Refaat, S. Abdelmoneim, Y. Rostom. Accepted as poster presentation in the Annual Meeting of the American Society of Clinical Oncology –ASCO – 4th – 8th June 2010, Chicago, IL, USA.
7. Hyperthermia and radiation therapy for locally advanced or recurrent breast cancer, K. D. Kiel, T. Refaat, N. Navanandan, V. Sathiaseelan ASCO Annual Meeting 2009, Orlando, FL, USA.
8. Junior Oncologists Fellowships Program, T. Refaat, Accepted for oral presentation in the 11th Pan Arab Oncology Congress, May 2011, Casablanca, Morocco.
9. Obesity and Cancer, T. Refaat, S. Abdelmoneim, Y. Rostom, accepted as Poster Presentation in the Global Forum for Health Research "Forum 10" held in Cairo, October 2006
10. Obesity and Cancer, T. Refaat, S. Abdelmoneim, Y. Rostom, accepted for Oral Presentation in the joint meeting of the 9th Annual Alexandria International Oncology Conference, Alexandria Clinical Oncology Department (ACOD), Alexandria Faculty of Medicine, Egypt and the 19th Annual Meeting of Kasr Al-‐Aini Center of Clinical Oncology and Nuclear Medicine (NEMROCK), Cairo University, Egypt entitled "Recent Advances and Future Directions in Cancer Treatment", November 2005.
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C. Research Support.
1. "Comparative evaluation of two methods of chemotherapy dose calculations according to the body weight and the body mass index in obese females with breast cancer" Thesis Submitted to Faculty of Medicine, University of Alexandria in partial fulfillment of the requirements of the degree of Master of Radiation Therapy. (PI )
2. "Female Study". An International Multi-‐Center Clinical Trial Protocol n CFEM345C2402 entitled "First – Line Treatment Of Postmenopausal Metastatic Breast Cancer. A Randomized, Multicenter Study Comparing Concurrent Vs Sequential chemo endocrine therapy with Letrozole Vs Letrozole Single Agent" Sponsored by Novartis. (Co-‐Investigator)
3. International Multi-‐center Clinical Trial on Pemitrexed (LY 231514) Sponsored by Eli Lilly Pharmaceutical Company entitled "Protocol H3E-‐AA-‐5037 (a) Open Label Single-‐Arm Phase II Study of ALIMTA in Patients with Advanced Non Small Cell Lung Cancer who have had Prior Chemotherapy. (Co-‐Investigator)
4. International Multi-‐center Study on Zometa (Zoledronic Acid, ZOL446) Sponsored by Novartis Pharmaceutical Company entitled "An Open-‐Label Clinical Study To Evaluate The efficacy and tolerability of Intravenous Zometa (Zoledronic Acid) 4mg In Cancer Patients In Whom Treatment with A Bisphosphonate is indicated". (Co-‐Investigator)
5. International Multi-‐center Clinical Trial on Bevacizumab therapy for advanced breast cancer (Protocol # MO19391) Sponsored by F. Hoffmann-‐La Roche LTD Pharmaceutical Company entitled "Open-‐label study of bevacizumab (AVASTIN®) plus taxanes monotherapy or in combination for the first line treatment of patients with locally recurrent or metastatic breast cancer". (Co-‐Investigator)
6. Phase III Multicenter International Clinical Trial on HCC – Best Recruiter Worldwide-‐. (Co-‐Investigator)
7. Pahse IV Multicenter International Clinical Trial on bisphosphonates therapy for Breast Cancer with Bone Metastases patients. (Ongoing)
8. Impact of maintaining adequate hemoglobin level on radiation therapy outcome for stage III cervical carcinoma (Co-‐Investigator)
9. Low dose continuous infusion Gemcitabine plus cisplatin versus standard dose Gemcitabine plus cisplatin in Stage III and IV Non Small Cell Lung Cancer. (Co-‐Investigator)
Grants Received:
1. WHO EMRO Unrestricted Travel Grant to attend the March Meeting of the International Federation of Medical Students' Associations, Kupio, Finland March 3rd – 9th 2000
2. WHO EMRO personal grant to establish an international campaign among medical students worldwide against TB, 2002 (6 months).
3. International Union Against TB and Lung Disease Unrestricted Travel Grant to attend the August Meeting of the International Federation of Medical Students' Associations, Ohrid, Former Yugoslav Republic of Macedonia, August 1st – 8th 2004
4. Ministry of Higher Education and State for Research Three Months Fellowship Grant – PAROWN Grant – in Robert H.Lurie Comprehensive Cancer Center, Radiation Oncology Department, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA July 27th –Sept 27th 2008.
5. USA NIH Office Of International Affairs Short-‐term Scientist Exchange Program for Three Months Fellowship – in Robert H.Lurie Comprehensive Cancer Center, Radiation Oncology Department, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA September 28th – December 28th 2008.
6. European School of Oncology Six Months Fellowship in Oscar Lambert Cancer Center, Lille II University, Lille, France July 15th – January 15th 2009.
7. Arab Medical Association Against Cancer Fellowship to supplement living expenses during six months fellowships in Oscar Lambert Cancer Center, Lille II University, Lille, France July 15th – January 15th 2009.
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8. European Society for Therapeutic Radiology and Oncology (ESTRO) Technology Transfer Grant for 3 weeks Training in Department of Radiotherapy and Radiobiology, Medical University of Vienna –January 2010-‐.
9. European Society of Medical Oncology, Clinical Unit Visit, one month fellowship in Oscar Lambret Cancer Center, Lille, France October 2010.
10. USA NIH Office Of International Affairs Short-‐term Scientist Exchange Program for one year Fellowship – in Robert H.Lurie Comprehensive Cancer Center, Radiation Oncology Department, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA September 1st 2011 – August 31st 2012.
11. USA NCI R25 training grant spot in Northwestern University September 1st 2011 – August 31st 2014.
12. I received grants to get the following trainings;
1. Clinical Research Training for Investigational Site Personnel (CRISP) Course #EN0501 – ClinfoSource, Online educational course on conducting clinical trials with respect to GCP guidelines accredited by University of Washington Office of Continuing Medical Education, July 2007.
2. ESMO training course on genitourinary malignancies held in NCI Cairo July 2006. 3. ASCO Multidisciplinary Cancer Management Training course held in NCI Cairo April 5th – 6th 2007. 4. Research Methodology Training course, 17th – 20th February 2007 Faculty and Leadership Development
Center (FLDP), University of Alexandria 5. Communication Skills Training course, 18th – 20th July 2006 Faculty and Leadership Development Center
(FLDP), University of Alexandria 6. Effective Teaching Training course, 15th – 18th July 2006 Faculty and Leadership Development Center
(FLDP), University of Alexandria 7. New Trends in Teaching Training course, 9th – 11th December 2006 Faculty and Leadership Development
Center (FLDP), University of Alexandria 8. Oncology Statistics for non statisticians, SPSS training by Lebanese Matrix-‐TRC training, research and
consulting academy, 25th – 27th April 2006 Alexandria, Egypt. 9. "Design & Conduct of Clinical Trials: Principles & Concepts, Attributes of a Successful Clinical Trial and
Protocol development in Oncology" Training by Thomas Brodowicz, M.D. Associate Professor of Medicine Director CECOG Medical University Vienna and Volker Wacheck, MD Dept. of Clinical Pharmacology, Medical University Vienna, Austria May 2007.
10. Giving monthly scientific seminars in the Clinical Oncology and Nuclear Medicine Department, Faculty of Medicine, University of Alexandria.
11. Regular Attendance of the annual national and international oncology conferences held in Egypt since 2003 till now
12. Member of the Organizing Committee of the 9th, 10th. 11th and 12th Annual International Alexandria Clinical Oncology Conference.
13. Pain Control in Cancer Patients Training Course, Alexandria, August 2007. 14. American Gynecology Oncology Group semi-‐annual meeting, Chicago, IL, July2008. 15. American Society of Radiation Therapeutic Oncology, Boston, USA, Sept 2008. 16. Lynn Sage Breast Cancer Symposium, Chicago, IL, USA 2009. 17. Training course on Radiosurgery, Northwestern University, Chicago, IL, 2009 and 2011. 18. Pan Arab Oncology Conference, May 7th – 9th 2009, Cairo, Egypt. 19. First Annual Conference of Beirut Arab University, April 22nd – 24th 2009, Beirut, Lebanon. 20. Annual Meeting of the American Society of Clinical Oncology, Orlando, FL, USA 2009 21. Organizing Committee coordinator, 30th Annual Alexandria Faculty of Medicine Conference
"Nanomedicine from Theory to Therapy" Alexandria, Egypt June 11th – June 12th 2009. 22. Cancer Radiation Biology Course Accredited by Northwestern University, Alexandria, Egypt June 13th –
14th, 2009.