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IMMUNOHEMATOLOGY (BLOOD BANKING) Midterm Examination I. MULTIPLE CHOICE 1. The following blood preservatives have a storage time of 21 days at 1-6 O C, EXCEPT: a. ACD b. CP2D c. CPDA-1 d. CPD 2. The preferred storage time and temperature for platelet concentrates prepared by centrifugation is: a. 5 days at 1-6 O C b. 5 days at 20-24 O C c. 5 days at 24-27 O C d. 5 days at 25-30 O C 3. Blood can be stored in CPDA-1 at 1-6 O C for how many days? a. 42 b. 35 c. 21 d. 7 4. Citrate-phosphate-dextrose (CPD), an improved preservative which eventually replaced ACD as the standard preservative solution was introduced by _______ in 1957: a. Landsteiner b. Hicks c. Drew d. Gibson 5. Who discovered the ABO blood group system? (Same choices #4) a. Landsteiner 6. Blood is stored at what temperature? a. 1-6 O C b. 20-24 O C c. 24-27 O C d. 37 O C 7. The following are advantages of stroma-free hemoglobin, EXCEPT: a. Long shelf life b. Very stable c. No antigenicity

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IMMUNOHEMATOLOGY (BLOOD BANKING)Midterm ExaminationI. MULTIPLE CHOICE1. The following blood preservatives have a storage time of 21 days at 1-6OC,EXCET!a. "C#b. C2#$. C#"-1d. C#2. The preferred storage time and temperat%re for platelet $on$entrates prepared by $entrif%gation is!a. & days at 1-6OCb. & days at 2'-2(OC$. & days at 2(-2)OCd. & days at 2&-*'OC*. +lood $an be stored in C#"-1 at 1-6OC for how many days,a. (2b. *&$. 21d. )(. Citrate-phosphate-de-trose .C#/, an improved preservative whi$h event%ally repla$ed "C# as the standard preservative sol%tion was introd%$ed by 0000000 in 11&)!a. 2andsteinerb. 3i$4s$. #rewd. 5ibson&. 6ho dis$overed the "+O blood gro%p system, .7ame $hoi$es 8(/a. 2andsteiner6. +lood is stored at what temperat%re,a. 1-6OCb. 2'-2(OC$. 2(-2)OCd. *)OC). The following are advantages of stroma-free hemoglobin, EXCET!a. 2ong shelf lifeb. 9ery stable$. :o antigeni$ityd. 3igh o-ygen a;nityetention in tiss%esd. #eep-free?e storage1. 6hi$h of the following is .are/ role.s/ of platelets,a. @aintain vas$%lar integrityb. Converts prothrombin to thrombin$. Antimately involved in se$ondary hemostasisd. "ll of these1'.The minim%m n%mber of platelets reB%ired in a platelet $on$entrate prepared from whole blood by $entrif%gation is!a. &.& - 1'11b. *.' - 1'1'$. &.& - 1'1'd. *.' - 1'1111."dditive sol%tions are approved for blood storage for how many days,a. (2b. *&$. 21d. )12.6hen a man possesses a trait that is e-pressed in all his da%ghters b%t notin his sons, the trait is!a. "%tosomal dominantb. "%tosomal re$essive$. X-lin4ed dominantd. X-lin4ed re$essive1*.Chara$teristi$ally, the trait is e-pressed in the father b%t is never passed from father to sonC instead all the da%ghters be$ome $arriers. The trait is said to be!a. "%tosomal dominantb. "%tosomal re$essive$. X-lin4ed dominantd. X-lin4ed re$essive1(.The Drst imm%noglob%lin prod%$ed after e-pos%re to an antigen isa. Ag5b. Ag"$. Ag@d. AgE1&.6hi$h of the following has the most important role in maintaining the sigmoid shape of the normal o-ygen-hemoglobin disso$iation $%rve,a. 3E $on$entrationb. CO2 $. 2,*-#5d. Temperat%re16.The following are $omponents of nat%ral imm%nity, EXCET!a. Anta$t s4inb. + $ells$. @a$rophagesd. :e%trophils1).Cell-mediated imm%nity involves whi$h one of the following gro%p of $ells,a. 1, 2, and *b. 1, *, and ($. 2, *, and (d. 1, 2, and (1E7O:7E,a. 3as shorter lag phaseb. 3as longer platea%$. "ntibodies $de$line slowlyd. Ag@ predominate21.6hat is the possible blood type of the oHspring between the mating of O and homo?ygo%s " individ%als,a. " onlyb. O only$. +oth of thesed. :one of these22.Af the mother and $hild are both blood type O, the father $annot be type!a. "b. +$. "+d. "ll of these2*.6hat part of the antibody mole$%le Dts into a re$eptor on the phago$yti$ $ell,a. Gab regionb. G$ region$. 3inge regiond. 9ariable region2(.6hi$h of the following is not a $omponent of the membrane atta$4 $omple-a. C*bb. C6$. C)d. Ch negative,a. 1''Jb. &'J$. 2&Jd. )&J*6.Af the parents have O and "+ blood type, 2what is the per$entage the oHspring will have type + blood,a. 1''Jb. &'J$. 2&Jd. )&J*).6hi$h imm%noglob%lin.s/ help.s/ initiate the $lassi$al $omplement pathway,a. Ag" and Ag#b. Ag@ only$. Ag5 and Ag@d. Ag5 only*everse typing$. #"T $rossmat$hing&(.6hen are the possible phenotypes of the oHspring between the mating of O and "+ individ%als,a. ", +, and Ob. " and +$. "+ obnlyd. ", +, "+, and O&&.6hat is the patientIs blood type if the patientIs red $ells do not aggl%tinate with anti-" and anti-+ antisera b%t his ser%m gives a positive rea$tion with both "1 and + 4nown $ells,a. "b. +$. "+d. O&6."nti-3 is fo%nd in the sera of individ%als of gro%p!a. "b. +$. Od. Oh&).Af the parents have O and "+ blood type, what are the $han$es the oHspring will have type + blood,a. 2&Jb. &'J$. )&Jd. 1''J&h)1.Af a #-positive person ma4es an anti-#, this person is probablya. artial #b. #-negative$. 6ea4 # as position eHe$td. 6ea4 # d%e to transmissible genes)2.E-tra$t of Dolichos biforus seeds is %sed to!a. Type +ombay gro%pb. Anhibit $omplement$. #iHerentiate gro%p "1 from gro%p "d. :one of these)*.The wea4 # phenotype is $onsidered!a. >h positiveb. >h negative$. Either of thesed. :either of these)(.3ow may genes en$ode the following >h antiges! #, C, E, $, e,a. Oneb. Two$. Threed. Go%r)&.Andivid%als who do not have the >hO .#/ fa$tor are $lassiDed as!a. >hn%llb. #F$. >h negatived. >h positive)6.The anti-rhes%s prod%$ed in laboratory animals by 2andsteiner and 6einerdeDned a new antigen system $alled!a. 26b. 2ewis$. >hd. Nidd)).Af a gro%p DCe/dce man marries a dce/dce woman, what per$entage of their oHspring $an be e-pe$ted to be #-negative,a. 1''Jb. &'J$. 2&Jd. )&J)h .E/d. Type O >h .E/