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RENNES BREST BRETAGNE The Bretagne bioservices directory 2010 www.capbiotek.fr

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Page 1: The Bretagne bioservices directory 2010 - ID2Santé innovation annuaire.pdfThe Bretagne bioservices directory 2010 ... Animal health Plant Health Cosmetics ... optimization, testing

RENNES

BREST

BRETAGNE

The Bretagne bioservicesdirectory 2010

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FROM MOLECULE TO MARKET

DIAGNOSTICS

MOLECULAR FARMING

The goals• To assemble the regional biotech actors under

a common banner.• To promote excellence in biotechnology and highlight

the region’s strengths: convergence between ICT andbiotechnologies, as well as specialized know-how in plantand animal production.

• To nurture cross-fertilization among different fields ofbiotechnology (healthcare, cosmetics, food industry).

Bioservices directoryThis catalog of bioservices attempts to list all the serviceproviders along the value chain that play a role in rapidlymoving your molecule of interest from discovery to market.

CRITT Santé Bretagne, the regional tech transfer centerfor health, medical devices, nutrition and biotech. It coordinated this directory and is your primary contact for further information.

CRITT Santé Bretagne is a not-for-profit organisation promoting co-operation between research units andcompanies involved in health-related R&D.

This directory was produced byContact : Anne-Claude LEFEBVRECRITT Santé Bretagne2 avenue du Pr. Léon BernardCS 3431735043 RENNES CédexTel.: +33 (0)2 23 23 45 81Fax: +33 (0)2 23 23 45 [email protected]

CAPBIOTEK, the regional initiative for the development of biotechnologiesin Bretagne

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RENNES

BREST

BRETAGNE

Bretagne: a strong track record in R&D• More than 2867 researchers in the public domain:

5th at national level

4 universities, more than 20 "grandes écoles", the major national research organizations (CNRS, Inra, Inserm, etc.)

ranked 5th nationally in terms of scientific publication and patent submission

• More than 4721 researchers in the private sectorMore than 700€M invested in R&D

(OST 2008 report)

Bretagne: a wide range of bioservices• More than 50 companies

• More than 20 technical core facilities

• More than 150M€ economic activity

• Bioservices for the human health, cosmetics, agriculture and energy industries

• Strong and growing SME culture ensuring personalized service for our R&D clients and fueling industry growth

(CRITT Santé Bretagne)

From screening and characterization, or market research and patent protection, to clinical studies and regulatory know-how, Bretagne has the bioservice you need!

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ABC Texture • • 5Actilait • • • • • • 6Adria • • • 7Afssa • • 8Agrimer • • 9Agrival • • 10Agrobio • • 11Algieplus • • • 12Anaximandre • • 13Animalerie de l'Université de Bretagne Occidentale • • 14Archimex • • • • 15Arist • • 16Armor Proteines • • 17Biodimar • • • 18Biopredic International • • 19Biotrial • • • 20C.RIS Pharma • • • 21Cabinet Vidon • • 22Cap Bleu Communication • • 23Capinov • • 24Capsugel • • 25CAREF • • • • • 26CBB Développement • • • • 27CCPA • • • • • 28CERNh • • 29CEVA • • • • • • • 30CIC-Inserm 0203 • • 31CIC-IT 804 • • 32CRLCC • • 33CTPA • • • 34DNA Microarray core facility • • 35Effiscience • • • 36Eurosafe • • 37

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H2P2 • • 38Hitex • • 39IciBio • • • 40ID.Mer • • • 41IDHESA Bretagne Océane • • 42ImPACcell • • • 43Innova Proteomics • • 44Installation expérimentale de l'Inra • • 45IPL santé • • 46IRMA • • • 47Korilog • • • 48Labofarm • • • 49Laboratoires Aditec • • 50LEHA • • 51LRBEVA • • • • 52MRic • • 53ONIS • • 54PIXEL • • 55Polaris • • • 56Polymaris Biotechnology • • • 57PRISM • • 58Proclaim • • • 59Prodiabio • • • • 60Safecos • • 61Science et Mer • • 62Seadev Fermensys • • • 63Sequencing/genotyping core facility • • 64STEPP • • • 65SynNanoVect • • • 66Vegenov • • • • • 67Voisin Consulting • • 68Xenoblis • • 69Xenopus biological resource center • • 70

Name of the structure

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Your guide to understanding the Bretagne value chainMARKET RESEARCH

BIOPRODUCTION BiosynthesisIndustrial biotechnologiesExtractionPurification

SCREENING Sourcingin vitroin situin vivo

INTELLECTUAL PROPERTY

CHARACTERIZATIONPhysical and chemical attributesEfficacyTarget identificationLead optimizationToxicology and toxicokinetic profilingPreclinical studies

VALIDATIONin vivo testsTechnological optimizationField trialsClinical investigations

FORMULATIONPharmaceutical formulationEncapsulationRheological measurementAdjuvant – excipient

REGULATORY SUPPORT AND REGISTRATIONQuality assuranceConsulting

MARKETING SERVICESPromotionCommercialCommunication

LegendThese icons represent the different business sectors

Human health

Animal health

Plant Health

Cosmetics

Agriculture

Environment/energy

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ABC Texture

MARKET RESEARCH

Description of services ABC Texture is a specialist co-contractor for the formulation of beauty products. We help you take high-quality, innovative products to market.

Thanks to our expertise in experiential marketing, ABC Texture truly focuses on a new dimension in service provision to the cosmetics industry. After an initial brief, we work with you to define your product's characteristics, from its texture and residual film properties through to ease of application and absorption time.

The products formulated by our engineers undergo rigorous quality controls and are tested to ensure their microbiological characteristics, safety, stability and efficacy, and include:

• Microbiological tests • Innocuous tests • Stability tests • Efficacy tests

Keywords formulation, cosmetics Contact Louisette BOURDIN

ZAC La ville es Passant II Rue Isaac Newton 35800 DINARD FRANCE Tel. +33(0)2 99 20 03 63 Fax: +33(0)2 99 19 52 20 [email protected] www.abctexture.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2004

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

5

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ACTILAIT Delegation for

Western France

MARKET RESEARCH

Description of services Actilait’s main activity is the analysis, optimization, testing and promotion of dairy products, whether produced on the farm, by small businesses or by multinationals. Our expertise and areas of activity include research in the public interest (to improve knowledge of dairy products and develop specific tools) and contract services (testing, consultancy, training, expert analysis, audits, etc.). The Western France satellite of Actilait includes:

• A biological resource center which proposes: (i) isolation, identification and characterization of various flora (including pathogenic and spoilage strains), (ii) Long-term storage of biological material (bacteria, yeasts, phages, complete ecosystems, etc.) entrusted to us by third parties, with over 2000 strains at present and (iii) expertise in the field of lactic acid bacteria bacteriophages (private collection of 200 phages).

• A Food safety team with expertise in the prevention and control of pathogenic risks and crisis management (hygiene).

Keywords dairy products, microbiology, isolation, bacteriophages of lactic acid bacteria, microbial libraries, consulting, hygiene Contact Jean-René KERJEAN

BP 50915 35009 RENNES CEDEX FRANCE Tel. +33(0)2 23 48 55 88 Fax: +33(0)2 23 48 55 89 [email protected] www.actilait.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1981

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

6

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ADRIA Développement

MARKET RESEARCH

Description of services ADRIA, the Association for R&D and Innovation in the Agrifood Industry, has been providing product support to Bretagne's agrifood industry for over 35 years. Our activities include: Research on food safety and preservation Product innovation: formulation, nutritional and functional analyses Technology consultancy Regulatory intelligence, scientific and technical document bases Intercompany training

Its resources: A microbiology and formulation lab A technical suite with pilot equipment A training room A large document base

Keywords consultancy, research, training, agrifood, innovation Contact Jean-Robert GEOFFROY

Créac’h Gwen 29196 QUIMPER FRANCE Tel. +33(0)2 98 10 18 18 Fax: +33(0)2 98 10 18 99 [email protected] www.adria.tm.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1975

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

7

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AFSSA Laboratory for the research

and study of veterinary medicinal products and

disinfectants

MARKET RESEARCH

Description of services As a reference laboratory for veterinary medicinal product residues and antimicrobial resistance, it participates in the surveillance and inspection processes associated with these health risks. It helps develop standards for methods to determine the effectiveness of disinfectants and also contributes to the evaluation of biocidal products in Europe.

The laboratory proposes the following services: • Veterinary drug residue analysis • Pharmacokinetic and toxicokinetic studies • In vitro and in vivo toxicology testing • Antimicrobial assays (bactericidal and virucidal agents), screening for

resistance genes Keywords veterinary drugs, food/feed contaminants, physical and chemical analysis, bactericidal activity, virucidal activity, genotoxicity, pharmacokinetics, toxicokinetics Contact Pascal SANDERS

BP 90203 35302 FOUGERES FRANCE Tel. +33(0)2 99 94 78 78 Fax: +33(0)2 99 97 78 80 [email protected] crl.fougeres.afssa.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1975

BUSINESS SECTOR

8

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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AGRIMER

MARKET RESEARCH

Description of services Agrimer is an industry leader in the harvesting, transformation and exploitation of marine resources. Thanks to full integration of a wide range of processes for extracting marine-derived ingredients, Agrimer sells raw materials and formulated products in bulk or individually packaged for your brand. Agrimer is a preferred supplier of thalassotherapy centers and spas.

The company offers access to several processes and services including: • Optimization of drying conditions and maintenance of the seaweed's

natural qualities. Shredding, sizing and micronization of dried seaweed (from a few centimeters down to the micron scale)

• Dry formulations: special equipment for handling powder products, from mixing through to custom packaging (sachets, jars, 30 g to 25 kg bags, etc.)

• Liquid formulations: extraction, filter sterilization, mixing, custom packaging from 3 ml to 20 l volumes

• Cosmetic processes: dual-stage reverse osmosis water treatment unit, vacuum turbo-emulsifier, custom packaging in all formats (tubes, jars, bottle, etc.)

Keywords seaweed, custom manufacturing, ingredients Contact André PRIGENT

Prat Menan 29880 PLOUGUERNEAU FRANCE Tel. +33(0)2 98 04 54 11 Fax: +33(0)2 98 04 55 15 [email protected] www.agrimer.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1992

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

9

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AGRIVAL

MARKET RESEARCH

Description of services Agrival is a specialist in the exploitation of vegetable co-products as food ingredients and active compounds in human health, e.g. glucosinolates from cauliflower, polyphenols from artichoke, sulforaphane from broccoli, quercetin from onion, lentinan from shiitake mushrooms, lycopene from tomato, etc. Custom extraction for other plants (seaweeds, fruits, cereals, aromatic herbs, etc.) is also available for our clients.

The laboratory transforms the raw materials into water-soluble powder for use in a variety of different industries (e.g. pharmaceutical, cosmetics, and food supplement). Keywords nutraceuticals, dietetics, cosmetics, aqueous and solvent-free extraction, natural, organic Contact Jean-Paul CHAPALAIN & Olivier MOAL

Kerisnel 29250 SAINT-POL-DE-LEON FRANCE Tel. +33(0)2 98 15 84 95 Fax: +33(0)2 98 15 84 95 [email protected]

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2007

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

10

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AGROBIO

MARKET RESEARCH

Description of services Agrobio offers its customers full-service microbiological, physical and chemical analysis and testing. The laboratory manages sample collection and logistics, and performs the required analyses with short turnaround times.

Agrobio acts as a one-stop shop for all your analytical needs. No need to worry about sample packaging and transport. We provide reliable results and our laboratory works in compliance with industry standards (GLP, COFRAC (ISO 17025)). Keywords cosmetics, nutraceuticals, efficacy testing, cell cytotoxicity, bioavailability, environmental testing Contact Henri LEBON

ZAC des 3 Marches 3 Impasse de la Jonchée 35132 VEZIN LE COQUET FRANCE Tel. +33(0)2 99 14 70 50 Fax: +33(0)2 99 14 70 51 [email protected] www.laboratoiresagrobio.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2005

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

11

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ALGIEPLUS

MARKET RESEARCH

Description of services The Algieplus research center is comprised of two units:

• A plant biotechnology laboratory which develops new preventive phytopharmaceutical tools. These reduce the need for conventional pesticide treatments by using long-acting natural compounds with an environmentally friendly toxicological profile.

• A technical testing station for trialling various solutions for screening and exploiting waste marine biomass, for use by local authorities.

Keywords marine biomass, crop protection, fertilizers, pesticides Contact Bruno JACOB

Espace Entreprises ZA de Kérantour Nord 22740 PLEUDANIEL FRANCE Tel. +33(0)2 96 20 48 41 Fax +33(0)2 96 22 01 24 [email protected] www.algieplus.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2007

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

12

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ANAXIMANDRE

MARKET RESEARCH

Description of services Anaximandre is a multimedia communications and ICT engineering agency that specializes in the development of information systems and software as a service for public- and private-sector stakeholders in biotechnology.

Anaximandre also develops applications in bioinformatics and molecular modelling and performs research on the modelling of biological processes.

Our services include: • Scientific and technical communication (multimedia, internet,

publishing, information graphics, computer-generated images, etc.). • Scientific and technical benchmarking for local authorities and

European Union projects. • Document management (literature searching, documentation) • Scientific review and audit (reports, competitive intelligence) • Exhibition stand design and logistics

Keywords multimedia, corporate communication, informatics, bioinformatics, publishing, open source, SaaS Contact Guy MORDRET

Parc d’innovation de Mescoat 29000 LANDERNEAU FRANCE Tel. +33(0)2 98 30 35 15 Fax: +33(0)2 98 30 32 65 [email protected] www.anaximandre.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1998

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTRE

13

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ANIMALERIE de l’Université de

Bretagne Occidentale

MARKET RESEARCH

Description of services The facility houses animal models for use in in vivo drug testing. The available models relate to human B-lymphoid diseases (lymphoma, chronic lymphocytic leukaemia) but custom development of animal models is possible (e.g. for colon cancer).

The following services are available: • Cancer drug screening • Syngeneic models, subcutaneous (SC), intraperitoneal (IP) or

intravenous (IV) xenografts (human tumours) and orthotopic grafts • Toxicity testing • per os, SC, IP, SC, IV and intramuscular treatment administration • Animal monitoring • Collection of blood and/or tissue samples

Keywords BSL2 animal facility, murine models, xenograft, toxicity, leukaemia, lymphoma, cancer Contact Séverine LOISEL

22 rue Camille Desmoulins CS 93837 29238 BREST CEDEX 3 FRANCE Tel. +33(0)2 98 01 81 52 Fax: +33(0)2 98 01 81 52 [email protected] www.univ-brest.fr/index.php?page=affiche_ composante&object=animalerie

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2009

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

14

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ARCHIMEX

MARKET RESEARCH

Description of services Archimex is a specialist in extraction processes, purification, and natural ingredients.

Our contract research and development center concentrates on the development of natural ingredients, third-party manufacturing, training and technology watching in the field of natural compound extraction and purification.

Archimex serves companies in the agrifood, pharmaceutical and cosmetics industries. Keywords natural ingredients, extraction, purification, compound isolation Contact Bernard MOMPON

Parc d’Innovation de Bretagne Sud CP31 56038 VANNES FRANCE Tel. +33(0)2 97 47 06 00 Fax: +33(0)2 97 47 56 90 [email protected] www.archimex.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1989

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

15

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ARIST Bretagne

MARKET RESEARCH

Description of services ARIST Bretagne fosters and supports economic/technical/scientific intelligence activities in Bretagne-based companies and economic stakeholders:

• Information management audits and project support for structuring and coordinating an intelligence-based approach

• Economic/technical/scientific/regulatory intelligence reports and updates

• Advice on brainstorming techniques for stimulating innovation: new product/market matching for fulfilling user needs or resolving technical or organisational problems; product design or re-design

• Intellectual property audits (status, needs and practices) • Technical and legal patent analysis for optimal protection of an

invention Keywords intellectual property, standards, regulatory affairs, information management, innovation consultancy Contact Alexandre COLOMB

Chambre régionale de commerce et d’industrie de Bretagne 1 rue du Général Guillaudot CS 14422 35044 RENNES CEDEX FRANCE Tel. +33(0)2 99 25 41 25 Fax: +33(0)2 99 25 41 10 [email protected] http://arist.bretagne.cci.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1983

BUSINESS SECTOR

16

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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ARMOR PROTEINES

MARKET RESEARCH

Description of services Armor Proteines, a subsidiary of the Soparind Bongrain Group (one of the world’s leading dairy groups) uses cutting edge and emerging technologies to provide a wide range of functional and nutritional ingredients.

Co-developer of new concepts, and a partner in strategic alliances, Armor Proteines is striving to become a world-wide specialist in milk fractionation and producer of value-added dairy ingredients and milk proteins (caseins, serum proteins, biopeptides, whey derivatives and lactose). Keywords ingredients, development, milk, fractionation, nutrition and healthcare, nutritional formulation Contact Dominique MORELLE

Le Pont 35460 SAINT BRICE EN COGLES FRANCE Tel. +33(0)2 99 18 52 52 Fax: +33(0)2 99 97 79 91 [email protected] www.armor-proteines.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1992

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

17

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BIODIMAR

MARKET RESEARCH

Description of services Biodimar has expertise in the extraction, purification and analysis of biomolecules:

• Collection of samples or organisms and supply of biomass or extracts • Compound purification • Screening for biological activities • Lyophilisation, grinding/shredding, extraction and concentration • Physical chemistry analyses • Antioxidant activity assays • Anti-aging activity assays

Our client sectors include pharmaceuticals, cosmetics, blue (marine-sourced) and green chemistry, and agrifood. Keywords biomolecules, extraction, purification, sample preparation, analysis, titration, biological screening Contact Eric DESLANDES

Université de Bretagne Occidentale UFR Sciences Techniques Bât. F 6 avenue de Gorgeu 29238 BREST FRANCE Tel. +33(0)2 98 01 66 50 Fax: +33(0)2 98 01 66 50 [email protected]

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2010

BUSINESS SECTOR

18

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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BIOPREDIC INTERNATIONAL

MARKET RESEARCH

Description of services Biopredic International is a worldwide supplier of human & animal primary cells, cell lines and tissues for research, drug discovery, drug development, pharmacology and toxicology. Keywords HepaRG cells, reagents, toxicology, tissues, organs, fluids, drug assays Contact Christophe CHESNE

8-18 rue du Professeur Jean Pecker Z.A Atalante Villejean 35000 RENNES FRANCE Tel. +33(0)2 99 14 36 14 Fax: +33(0)2 99 54 44 72 [email protected] www.biopredic.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1993

BUSINESS SECTOR

19

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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BIOTRIAL

MARKET RESEARCH

Description of services The contract research organization Biotrial performs non-clinical and clinical studies for the pharmaceutical, cosmetic and agrifood industries.

Biotrial's services include: • Non-clinical pharmacology • Performance of Phase I clinical pharmacology trials • Data management, biostatistics and medical writing • Management of home-based clinical trials: Phase II and III trials and

oncology studies • Core lab: central ECG/MRI reading • QA and regulatory affairs

Keywords clinical studies, pharmacology, biostatistics, oncology, patients Contact Jean-Marc GANDON

7-9 rue Jean Louis Bertrand Technopôle Atalante Villejean 35000 RENNES FRANCE Tel. +33(0)2 99 59 91 91 Fax: +33(0)2 99 59 91 99/97 [email protected] www.biotrial.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1989

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

20

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C.RIS Pharma

MARKET RESEARCH

Description of services C.RIS Pharma is a contract research organisation (CRO) which specializes in the preclinical development of drug candidates. It has expertise in the fields of cancer, neurodegenerative disease, metabolic and genetic diseases, agrifood and cosmetics.

The CRO has particular expertise in the characterisation of active compounds, drug target identification and validation, and toxicological and metabolic studies.

C.RIS Pharma can also develop customer-specific assays or cell-based models on request.

C.RIS Pharma offers its services to pharmaceutical and biotech companies (efficacy assays, pharmacology and toxicology), the fine chemicals industry (biological activity), agrifood and cosmetics firms (antioxidant properties, allergic properties, efficacy, safety/toxicological studies, etc.). Keywords preclinical development, in vivo, in vitro, identification Contact Pierrick AUVRAY

Parc Technopolitain Atalante Sain-Malo 35400 SAINT-MALO FRANCE Tel. +33(0)2 99 19 69 70 Fax: +33(0)2 23 52 16 41 [email protected] www.c-rispharma.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2003

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

21

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CABINET VIDON

MARKET RESEARCH

Description of services Cabinet Vidon offers a range of services and consultancy in the field of intellectual property: patent filing, trademarks, registered designs, software protection and copyright.

• Drafting collaborative R&D contracts (patent licensing and assignment, know-how transfer, joint research)

• Intellectual property litigation • Patent searches & surveys, examination of patent validity

Keywords intellectual property, patents, trademarks, registered designs, contracts, consultancy, audit, litigation Contact Patrice VIDON

168 rue de Jouannet BP 90333 Technopole Rennes Atalante 35703 RENNES CEDEX 7 FRANCE Tel. +33(0)2 99 38 23 00 Fax: +33(0)2 99 36 02 00 [email protected] www.vidon.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1988

BUSINESS SECTOR

22

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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CAP BLEU COMMUNICATION

MARKET RESEARCH

Description of services Cap Bleu Communication offers a range of services and consultancy in the fields of marketing and communication, and specializes in brand creation positioning and image management.

Our services include: • Capsentis, a think-tank equipped with tools for performing surveys,

identifying trends and generating new methodologies in France and internationally

• Project support for new product development, market launch and market access (China, etc.)

• A specialized media library for our customers, with over 65,000 photos • Purchasing of advertising space in the specialist press, media plan

creation • Web 2.0 • Development of new ICTs

Keywords marketing, brand image, innovation, positioning, ICT, consultancy, design, packaging, DTP, nutritional health, cosmetics, communication, business intelligence, international business Contact Evelyne OLLIVIER-LORPHELIN

Campus de Ker Lann Parc de Lormandière Bat. A Rue Maryse Bastié 35170 BRUZ FRANCE Tel. +33(0)2 99 05 51 01 Fax: +33(0)2 99 05 53 21 [email protected] www.cap-bleu.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

BUSINESS SECTOR

23

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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CAPINOV

MARKET RESEARCH

Description of services Capinov's multidisciplinary and complimentary staff offers a wide range of services to stakeholders in the agricultural, agrifood and environmental sectors.

We can meet your needs in terms of analysis, whether you have a routine analytical need, or are searching for a specific area of expertise, technique, or analytical method, or services such as training, consultancy, sampling methods, etc.

Capinov is GPL and COFRAC (ISO 17025) labelled. Keywords consultancy, analysis, effluents, pollutants, contaminants, technology watching, food labelling Contact Jean-Luc HARDY

Z.I. de Lanrinou 29206 LANDERNEAU CEDEX FRANCE Tel. +33(0)2 98 25 30 24 Fax: +33(0)2 98 25 32 74 [email protected] www.capinov.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1965

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

24

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CAPSUGEL

MARKET RESEARCH

Description of services As a division of Pfizer Inc., Capsugel custom-develops, manufactures and markets gelatine capsules, for the use in drug and dietary supplement applications. Keywords gelatine capsules, pharmaceuticals, food, delivery systems, nutrition, GMP Contact Thierry LE BOURGEOIS

Z.I Camagnon BP 320 56803 PLOERMEL CEDEX FRANCE Tel. +33(0)2 97 72 10 00 Fax: +33(0)2 97 72 15 00 [email protected] www.capsugel.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1995

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

25

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CAREF

MARKET RESEARCH

Description of services CAREF is an independent, private-sector R&D laboratory for biopolymer extraction and purification and the elaboration of analytical files for the pharmaceutical industry.

CAREF is also involved in pharmaceutical formulation, the validation of analytical control methods, compatibility studies and real-time stability testing.

In addition, CAREF provides analytical services for biopolymers (DNA, oligosaccharides, hyaluronic acid, etc.) as well as the routine pharmaceutical quality control (physical-chemical and microbiological testing). Keywords custom analysis, stability testing, consultancy, formulation, project support, purification Contact Michèle RANSON

Z.I de l’Aumaillerie 35133 JAVENE FRANCE Tel. +33(0)2 99 99 37 37 Fax: +33(0)2 99 99 05 36 [email protected] www.javenech.com/laboratory/laboratory.html

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1997

BUSINESS SECTOR

26

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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CBB Développement

MARKET RESEARCH

Description of services Development of active compounds/ingredients for use in the cosmetics, health food, food supplement, animal feed, food and environment industries:

• Technical feasibility and industrial transfer of fermentation-based process for producing polysaccharides for the pharmaceuticals and cosmetics industries

• Enzymatic synthesis of fatty acid esters • Development of enzymatic protein hydrolysates for nutritional health

markets • Analysis of the fermentation step in the production of animal probiotics • Support for the development of biological products for processing

organic material

Project engineering in biotechnology and fine chemicals (fermentation, enzyme engineering, extraction, purification and chemical synthesis):

• Scientific intelligence and literature reports • R&D consultancy and strategy • Expert technical reports • Feasibility studies • Project management and financial engineering

Keywords innovation, technology transfer, biotechnology, fine chemicals, fermentation, enzyme engineering, biomolecules, active compounds, ingredients Contact Gilbert BLANCHARD

9 rue du Clos Courtel 35700 RENNES FRANCE Tel. +33(0)2 99 38 33 30 Fax: +33(0)2 99 63 76 88 [email protected] www.cbb-developpement.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1975

BUSINESS SECTOR

27

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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CCPA

MARKET RESEARCH

Description of services CCPA is a service company with over 40 years of experience in the animal health and nutrition sectors.

The company's core positioning in these two markets, its professionalism and its broad range of skills enable CCPA to provide optimal project support to its customers in their various business areas.

CCPA provides services in: • Chemical & biological testing • Quality & environment • Animal production science • Formulation • Production • Specialist software packages • Sales & marketing, PR

Keywords consultancy in animal nutrition and health, chemical and biological testing, premix, adjuvants, nutritional products Contact Jean-Jacques BLAIN

Zone d’activités Nord-Est du Bois de Teillay 35150 JANZE FRANCE Tel. +33(0)2 99 47 53 00 Fax: +33(0)2 99 47 53 92 [email protected] www.ccpa.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1966

BUSINESS SECTOR

28

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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CERNh

MARKET RESEARCH

Description of services The CERNh (Human Nutrition Research and Teaching Center) offers a wide range of services for the development of new food products:

• Performance of clinical trials in human nutrition • Technical and regulatory affairs support on the formulation and

packaging of food products or food supplements • Health claims support for AFSSA and EFSA applications • Literature surveys and reviews

CNERh also provides expertise in nutritional health, dietetics and preventive health for the general public (cardiovascular disease, metabolic diseases, diabetes and cancer). Keywords clinical trials, claims, nutrition, nutraceuticals, consultancy Contact Bernard SCHMITT

Centre Hospitalier de Bretagne Sud 27 rue du Docteur Lettry BP 2233 56322 LORIENT CEDEX FRANCE Tel. +33(0)2 97 37 48 07 Fax: +33(0)2 97 37 48 07 [email protected] www.cern-nutrition.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1979

BUSINESS SECTOR

29

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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CEVA

MARKET RESEARCH

Description of services CEVA is the only technical center of its kind in Europe. It supplies services to companies designing and developing industrial products based on marine ingredients (seaweeds, microalgae, marine plants, sea water) and to local authorities confronted with the massive growth or washing-up of seaweed and marine plants. Keywords algae, seaweed, microalgae, halophytic plants, marine phanerogames, marine biotechnologies, extraction, purification, characterization, formulation, active compounds, ingredients, algal cultivation, aquaculture Contact Marc DANJON

Presqu’île de Pen Lan BP 3 22610 PLEUBIAN FRANCE Tel. +33(0)2 96 22 93 50 Fax: +33(0)2 96 22 84 38 [email protected] www.ceva.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1982

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

30

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CIC-Inserm 0203

Centre d’investigation clinique de Rennes

MARKET RESEARCH

Description of services The Rennes Clinical Investigation Center (CIC) masters all the professional skills needed to perform clinical research - from first-in-man studies on small groups of healthy subjects or patients to large-scale, multicenter trials in France or across Europe. The Center works closely with nearby research labs and the other CICs in France.

The CIC does not place any restrictions on the study theme, design or type of sponsor. Its work covers research in healthy controls and in patients (with or without direct individual benefit) in physiology, pathology, clinical pharmacology, drug trials, genetics, epidemiology, the assessment of diagnostic methods and the identification of prognostic factors. Keywords clinical studies, clinical pharmacology, drug trials, pharmaco-epidemiology, pharmacogenetics, epidemiology, physiological and pathology studies Contact Yves DEUGNIER & Eric BELLISSANT

CHU de Rennes Hôpital de Pontchaillou Centre cardio pneumologie Pavillon Clémenceau 2 rue Henri Le Guilloux 35033 RENNES CEDEX 9 FRANCE Tel. +33(0)2 99 28 37 15 Fax: +33(0)2 99 28 37 22 [email protected] www.cic-rennes.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2002

BUSINESS SECTOR

31

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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CIC-IT 804 Centre d’investigation clinique – Innovation

technologique de Rennes

MARKET RESEARCH

Description of services The Rennes CIC-IT 804 Clinical Investigation Center's mission is to innovate and perform clinical research on medical technologies in general, and cardiovascular diagnostic and therapeutic devices in particular.

The center is structured around the Signal and Image Processing Laboratory, several clinical departments (cardiology and vascular disease, cardiac, vascular and thoracic surgery, functional investigation, anaesthesia and intensive care, paediatric medicine) and a number of industrial partners.

The clinicians, medtech engineers, biostatisticians and clinical research technicians have multidisciplinary skills and offer access to their expertise for:

• The clinical evaluation of innovative technologies: design and coordination of multicenter studies, elaboration of specific methodologies and assistance with drafting clinical guidelines

• Technological innovation: identification of clinical needs, definition of new concepts, prototyping support for devices and methods generated in upstream research and assistance with new product development

Keywords technological innovation, clinical research, medtech, clinical evaluation, cardiovascular Contact Philippe MABO & Guy CARRAULT

Hôpital de Pontchaillou Centre cardio pneumologie 2 rue Henri Le Guilloux 35033 RENNES CEDEX 9 FRANCE Tel. +33(0)2 99 28 25 09 Fax: +33(0)2 99 28 25 09 [email protected] www.ltsi.univ-rennes1.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2008

BUSINESS SECTOR

32

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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CRLCC Department of

Biology Rennes

MARKET RESEARCH

Description of services Central laboratory for clinical trials

• Routine laboratory tests (biochemistry, hematology, immunoassays, hemostasis). COFRAC accreditation number: 1-1347

• Multiplex ELISA assays • RIA Assays • Cell culture facilities • Molecular tests

Keywords central laboratory, routine laboratory tests, immunoassays, cell cultures, flow cytometry, human, animal Contact Véronique QUILLIEN

Department of Biology Centre Eugène Marquis Avenue Bataille Flandres Dunkerque CS 44229 35042 RENNES CEDEX FRANCE Tel. +33(0)2 99 25 31 90 Fax: +33(0)2 99 25 31 64 [email protected]

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN

BUSINESS SECTOR

33

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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CTPA

MARKET RESEARCH

Description of services For over 20 years, the CTPA has been performing field-based validation trials in porcine, bovine and avian species.

If you need to evaluate product efficacy and/or safety under "real-life" conditions, the CTPA is your ideal partner for designing, operating and interpreting field trials.

The CTPA tests products for the animal health industry (antibiotics, vaccines, antiparasitic agents, anti-inflammatories, etc.) and the agrifood industry (growth factors, probiotics, enzymes, aromas, acidifiers, disinfectants, insecticides, etc.)

The CTPA also provides statistical analyses, technology surveys, literature reviews, training sessions, field surveys and advice on tech transfer & funding. Keywords field trials, drug, agrifood industry, pig, poultry, bovine Contact Alassane KEITA

2 rue Jean Rostand BP 7 22440 PLOUFRAGAN FRANCE Tel. +33(0)2 96 76 61 68 Fax: +33(0)2 96 76 61 69 [email protected] www.zoopole.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1986

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

34

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DNA Microarray

core facility

MARKET RESEARCH

Description of services The DNA microarray facility designs and develops coherent methods and tools in functional and integrative genomics (dedicated, high-throughput approaches). Our services include:

• Transcriptomics: whole-genome chips (Agilent, Illumina) for studying mRNA expression and microRNA/qPCR assays (Applied Biosystems - SybrGreen and Taqman)

• Genomics (gene copy number changes and/or genotyping): whole-genome chips (Agilent and Illumina Infinium), qPCR (Applied Biosystems - SybrGreen and Taqman), pyrosequencing (Qiagen) and dedicated chips (Illumina GoldenGate)

• Methylomics: CpG Island 244K arrays (Agilent), HumanMethylation27 arrays (Illumina), bisulfite pyrosequencing (Qiagen) and qPCR (Applied Biosystems, SybrGreen and Taqman)

• Statistical and bioinformatics analyses of microarray data: calibration, normalization, differential analysis, biological classification and contextualisation, and integrated functional/genomic annotation (identification of correlations between molecular changes).

Keywords DNA microarrays, functional and integrative genomics, biomarkers Contact Jean MOSSER

Faculté de Médecine 2 avenue du Pr Léon Bernard CS 34317 35043 RENNES CEDEX FRANCE Tel. +33(0)2 23 23 44 92 Fax: +33(0)2 23 23 44 78 [email protected] http://ouestgenopuces.univ-rennes1.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2003

BUSINESS SECTOR

35

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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EFFISCIENCE

MARKET RESEARCH

Description of services As an expert in applying pharmacology-standard strategies to the fields of biology, dermatology and beauty, Effiscience provides project support for the development of new active compounds and can even assume responsibility for entire product development phases.

The efficacy trials offered by Effiscience address a range of cosmetic claims and can be performed separately or as pre-formatted or custom-designed packages. One of Effiscience's unique features is its ability to offer an interface between biochemistry and pharmacology on one hand and histology and immunohistochemistry on the other. Keywords dermocosmetics, pharmacology, histology, immunohistochemistry, development of active compounds Contact Jean-Eric BRANKA

178 rue de Brest 35000 RENNES FRANCE Tel. +33(0)2 99 33 97 77 Fax: +33(0)2 99 33 97 78 [email protected] www.effiscience.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2003

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

36

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EUROSAFE

MARKET RESEARCH

Description of services Eurosafe is a toxicity testing lab for cosmetic ingredients and cosmetic products. Our laboratory is GLP-compliant, and we perform safety tests on finished products:

• Het Cam, NRR and BCOP tests • Tests on Prediskin skin explants

and on ingredients: • Genotoxicity tests: AMES, micronucleus, MLA • Phototoxicity: OECD 433 • Skin permeability

Keywords safety tests, safety, microbiology, allergens, genotoxicity tests, ingredients Contact Dominique DE JAVEL

Parc d’activité de la Bretèche Bâtiment B1 35760 SAINT-GREGOIRE FRANCE Tel. +33(0)2 99 23 46 46 Fax: +33(0)2 23 25 29 74 [email protected] www.eurosafe.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2001

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

37

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H2P2 Plate-forme

histopathologie haute précision

MARKET RESEARCH

Description of services This facility offers standard histology lab services plus custom laser microdissection.

Applications: • Diagnostics/screening (toxicity, mode of action) on the tissue level • Understanding of physiological and physiopathological mechanisms • Drug target discovery • Analysis of bioactive molecules • Pharmacology, toxicology, pathology • Tissue genomics

Keywords laser microdissection, tissue microarrays, pharmacotoxicology, immunohistochemistry, nucleic acid extraction, amplification Contact Alain FAUTREL

Université de Rennes 1 2 avenue du Pr Léon Bernard CS 34317 35043 RENNES CEDEX FRANCE Tel. +33(0)2 23 23 47 95 Fax: +33(0)2 23 23 49 29 [email protected] http://histopathologie.univ-rennes1.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2007

BUSINESS SECTOR

38

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

Page 41: The Bretagne bioservices directory 2010 - ID2Santé innovation annuaire.pdfThe Bretagne bioservices directory 2010 ... Animal health Plant Health Cosmetics ... optimization, testing

HITEX SAS

MARKET RESEARCH

Description of services As your industrial partner, HITEX SAS puts its human and supercritical CO2 resources at your disposal.

Our expertise in all supercritical CO2 processes (extraction, fractionation, separation, purification, impregnation and formulation), allows us to accompany your project from beginning to end:

• In R&D: to develop new products and processes • At scale-up: to produce at the lowest cost using supercritical CO2 • Providing technical support: improvement of processes including

purification

Our client sectors include perfumes/aromas, cosmetics, biomedical and pharmaceuticals, nutraceuticals and phytotherapy, and chemistry. Keywords extraction, fractionation, purification, supercritical CO2, molecular distillation Contact Irène LAMOUR

Rue Louis Lefèvre Utile Z.I. Pentaparc BP 33601 56306 VANNES FRANCE Tel. +33(0)2 97 68 88 88 Fax: +33(0)2 97 68 88 80 [email protected] www.hitex-co2.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1997

BUSINESS SECTOR

39

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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ICIBIO

MARKET RESEARCH

Description of services IciBio provides medical & scientific writing, literature searches and analyses, documentation, biological sequence searches, bibliographic database implementation, patent priority searches and English / French translation. Keywords scientific information, bibliography, documentation, translation, writing, medical Contact Françoise BONNICI

4 chemin de Bellevue 22520 BINIC FRANCE Tel. +33(0)2 96 73 33 03 Fax: +33(0)2 96 73 33 03 [email protected] www.icibio.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1997

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

40

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ID.MER

MARKET RESEARCH

Description of services ID.Mer contributes to the development and promotion of the sea product industry:

• Coordination of cooperation between scientific and technical research and the sea product industry

• Trials for optimizing sea product processing techniques: design, innovation, development

• Information dissemination, technology watching, knowledge transfer, consultancy

• Organisation of events for the sea product industry • Exploitation of marine co-products in the human & animal health and

nutrition sectors Keywords development, manufacturing, expert analysis, sea products, co-products, exploitation, biotechnology Contact Patrick ALLAUME

2 rue Batelière 56100 LORIENT FRANCE Tel. +33(0)2 97 83 86 83 Fax: +33(0)2 97 37 11 03 [email protected] www.idmer.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1987

BUSINESS SECTOR

41

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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IDHESA Bretagne Océane

MARKET RESEARCH

Description of services IDHESA Bretagne Océane provides consultancy and expert analysis in the fields of water quality, the environment and food hygiene.

The laboratory is COFRAC 1-1827 and 1-1828 accredited and is certified by the French Ministries of Health, and of Environment and Agriculture for:

• Analysis of drinking water, river/coastal/marine water, effluent water, sludge, leachates, soil and sediments

• Physical chemistry analyses, micropollutants, microbiological testing for drinking water, river/coastal/marine water, effluent water, food products, biological matrices, sludge, leachates, composts, soil and sediments

• Animal health

IDHESA also persues internal R&D in various fields of activity. Keywords consultancy, expert appraisal, analysis, R&D, water, environment, food, animal health Contact Eric LAPORTE

Gaël DURAND

Technopôle Brest-Iroise 120 avenue A. de Rochon BP 52 29280 PLOUZANE FRANCE Tel. +33(0)2 98 34 11 00 Fax: +33(0)2 98 34 11 01 [email protected] www.idhesa.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2007

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

42

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IMPACCELLPlate-forme

Imagerie – puces à cellules

MARKET RESEARCH

Description of services ImPACcell offers its skills, expertise and analytical resources in large-scale biological screening assays:

Toxicity and activity assays for chemicals, environmental pollutants and toxins, etc.

Specific liver toxicity assays

Optimization of cell models for liver toxicity research

Cell-based functional assays using fluorescent labels

Determination of tissue-specific characteristics

Multiplexed gene expression analysis

Advice on cell culture and models

High-throughput in situ imaging of organized cell systems. Keywords toxicology, pharmacology, healthcare, cancer, nutrition Contact Christiane GUILLOUZO

Faculté de Médecine Bâtiment 8 2 avenue du Pr Léon Bernard 35043 RENNES FRANCE Tel. +33(0)2 99 54 74 00 Fax: +33(0)2 99 54 01 37 [email protected] http://imagerie-puces-a-cellules.univ- rennes1.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2005

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

43

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INNOVA PROTEOMICS

MARKET RESEARCH

Description of services The proteomics service company Innova Proteomics provides R&D and analytical solutions for protein and peptide products.

Innova Proteomics offers a wide range of services with various degrees of sophistication, from protein characterization through to full-service, large-scale proteomics programmes: protein identification, quality control of biomanufactured proteins, biomarker development, toxicoproteomics, exploitation of bioproducts and ingredients, and the identification of bio-active proteins and peptides.

Innova Proteomics has developed a process for the discovery and identification of natural, bio-active peptides. The process screens bioresources for novel therapeutic peptides or new ingredients. Keywords proteomics, peptide, proteins, biomarkers, identification, drug discovery, quality control Contact Nathalie MELAINE

Campus de Beaulieu Bât. 24 CS 2407 263 avenue du Général Leclerc 35042 RENNES CEDEX FRANCE Tel. +33(0)2 23 23 52 80 Fax: +33(0)2 23 23 52 82 [email protected] www.innova-proteomics.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2003

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

44

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INSTALLATIONEXPERIMENTALE

DE L’INRA

MARKET RESEARCH

Description of services This field station has a wide range of tools for use in research into pig physiology, pig production systems and human nutritional health (in which the pig is used as animal model):

• A conventional 200-sow herd • Ongoing constitution of a herd of minipigs • Access to other animal species: poultry, calves, rabbits, etc. • Trial housing: farrowing houses, housing for weaned piglets, growing

pigs in individual or group sties, young breeding sows, climate-controlled housing

• Special buildings and tools, such as operating rooms, an imaging platform, respiratory chambers, rooms for behavioural testing, monitoring or nutritional status investigations

• A mill and a slaughterhouse • Specialist operatives

It also supplies experimental animals to third parties and provides a number of services, such as the production of test batches of animal feed and data collection on carcasses post-slaughter or under controlled conditions. Keywords pig production systems, pigs, minipigs, animal feed and nutrition, human food and nutrition, healthcare Contact Jean NOBLET

UMR SENAH Domaine de la Prise 35590 SAINT-GILLES FRANCE Tel. +33(0)2 23 48 52 00 Fax: +33(0)2 23 48 50 80 [email protected] www.rennes.inra.fr/senah/install.html

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1980

BUSINESS SECTOR

45

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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IPL SANTE,

ENVIRONNEMENT DURABLES BRETAGNE

MARKET RESEARCH

Description of services IPL offers analytical services for a variety of environmental matrices (water, sludges, sediments, air, etc.).

IPL is a specialist in biodegradability studies of plastics and the characterization of antifouling paints.

Certified by the French Ministry of Health and Ministry of the Environment, the laboratory is also GLP-compliant for residue studies and COFRAC accredited (ISO 17025). Keywords physical chemistry, biodegradability, microbiological analyses, water, pesticides Contact Elisabeth LE FUR

Parc Technologique de Soye 4 rue de Galilée 56270 PLOEMEUR FRANCE Tel. +33(0)2 97 80 80 80 Fax: +33(0)2 97 80 80 86 [email protected] www.ipl-groupe.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1984

BUSINESS SECTOR

46

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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IRMA

MARKET RESEARCH

Description of services The IRMA performs contract/collaborative development of innovative technologies in environmental and energy sectors:

• Development of catalytic or adsorption-based technologies for reducing atmospheric pollutant emissions (NOX, N2O, COV, NH3, CO, etc.). Production of catalysts

• Waste processing and exploitation: treatment of pig slurry, plastic recycling, thermolysis of organic waste (four pilot trials with analysis of the material/energy balance), prototype engineering and production

• Production of hydrogen from fossil or renewable hydrocarbon sources (linked to fuel cell development)

The IRMA also provides the following services: • Physical-chemical analyses (SEM, EDX, XRD, etc.) and on-site gas

emission analyses • Synthesis and processing of mineral products • Expert analysis: audits, project engineering and consultancy • Elaboration of solvent management plans – emissions control

procedures – regulatory intelligence – feasibility studies – technical, economic and environmental analyses of equipment and installations

• Carbon balance analysis (ADEME-accredited) and greenhouse gas accounting

Contact Christian HAMON

9 rue Galilée Parc Technologique de Soye BP 64 56274 PLOEMEUR CEDEX FRANCE Tel. +33(0)2 97 83 55 55 Fax: +33(0)2 97 83 38 83 [email protected] www.irmatech.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1990

BUSINESS SECTOR

47

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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KORILOG

MARKET RESEARCH

Description of services Korilog is a bioinformatics company providing academic and industry research laboratories with next generation software solutions in the key areas of biological data integration, exploration, management and visualization.

Korilog provides ready-to-use graphical softwares (koriblast.com, koriviewer.com) enabling comprehensive exploration of sequence databanks and associated data, from raw nucleotide and protein sequences up to functions, 3D structures and pathways.

The company provides expert software development services to integrate specialized modules in Korilog's software, or create tailored tools and databanks to support researchers in their R&D activities. Keywords genomics, proteomics, drug discovery, bioinformatics Contact Patrick DURAND

BP 34 56190 MUZILLAC FRANCE Tel. +33(0)9 60 36 80 38 Fax: +33(0)2 97 42 88 20 [email protected] www.korilog.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2004

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

48

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LABOFARM

MARKET RESEARCH

Description of services Labopharm is a veterinary laboratory which specializes in biomolecular diagnostics (genetic testing and PCR assays).

With 20 years of experience in the field of veterinary diagnostics, the Labopharm laboratory is at the cutting edge of disease screening technologies. For example, the molecular biology unit can screen for over thirty bacterial and viral animal pathogens. The unit's operating procedures comply with the rigorous standards required for the French COFRAC accreditation (ISO 17025).

Labopharm is highly involved in selection and breeding in the poultry-, pig- and fish-farming sectors.

Labopharm is now pursuing its development by aligning its analytical methods with the technologies generated in research labs and by developing new tests that meet the needs of farmers and veterinarians. Keywords genetic screening for pathogens, DNA bird sexing, genetic testing, PCR, veterinary health Contact Jean LE GUENNEC

4 rue Théodore BOTREL BP 351 22603 LOUDEAC FRANCE Tel. +33(0)2 96 28 63 43 Fax: +33(0)2 96 66 08 88 [email protected] www.labofarm.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1990

BUSINESS SECTOR

49

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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LABORATOIRES

ADITEC

MARKET RESEARCH

Description of services Laboratoires Aditec is an expert in dry powder technologies and formulations, such as effervescent products and micro-encapsulated ingredients.

Our products are supplied to leading food supplement and feed additive retailers. Laboratories Aditec is a top choice for high-quality, full-service, sub-contracted manufacturing of nutraceutical products. Keywords effervescent products, granulation, service provision, custom manufacturing, encapsulation Contact Alexandre RAGUET

55 boulevard Jules Verge BP 10180 35803 DINARD CEDEX FRANCE Tel. +33(0)2 99 16 52 05 Fax: +33(0)2 99 16 52 14 [email protected] www.laboratoiresaditec.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1996

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

50

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LEHA

MARKET RESEARCH

Description of services The LEHA laboratory provides analytical and consultancy services. It has over 25 years' experience of assisting manufacturers, retailers, small business and local authorities with their quality control and product/service development.

Our services include physical chemistry analyses, nutritional analyses, bacteriological analyses, sensory testing, bovine spongiform encephalopathy screening.

Our fields of expertise include: • Food products • Pet food • Cosmetics • Hygiene products

Keywords testing, quality control, consultancy, training, audit, food, hygiene, beauty products Contact Katicha MENGUY

Les Tertres Noirs BP 40526 35500 VITRE CEDEX FRANCE Tel. +33(0)2 99 74 10 54 Fax: +33(0)2 99 74 10 55 [email protected] www.leha.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1984

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

51

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LRBEVA NUTRITION

MARKET RESEARCH

Description of services Incorporated in 1987 as NUTRINOV, the company has since been renamed as LRBEVA NUTRITION. Our core skill is the development of innovative food products for manufacturers and retailers.

Creating a new food product or introducing a new ingredient while maintaining the product's organoleptic and functional qualities requires a rigorous approach that can be likened to pharmaceutical product development.

LRBEVA NUTRITION's experienced staff provides comprehensive project support - from the idea through to market launch:

• Prototype development • Scientific analysis, health claims and the implementation of trials • Product development and industrial scale-up

LRBEVA NUTRITION handles these and other steps for its industrial customers. Keywords formulation, design, development, evaluation, regulatory support, food products Contact Loïc ROGER

Rue Siméon Poisson Campus de Ker Lann 35170 BRUZ FRANCE Tel. +33(0)2 99 52 54 00 Fax: +33(0)2 99 52 54 01 [email protected] www.lrbeva.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2004

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

52

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MRic Microscopy Rennes

imaging center

MARKET RESEARCH

Description of services The Rennes microscopy and imaging center (MRic) comprises 4 facilities:

• MRic-ALMF: advanced light microscopy • MRic-NANO: NanoSIMS (high-resolution secondary ion mass

spectrometry) • MRic-MPM: multiphoton microscopy • MRic-TEM: transmission electron microscopy

MRic offers access to imaging systems, scientific and technical support in experimental and project design and training in microscopy techniques. We have special expertise in:

• Rapid, real-time in vitro cell imaging • Structural analysis • Molecular and atomic imaging • Protein-protein interactions (FRET and FLIM) • In vitro enzyme assays • Correlation fluo-TEM and Fluo-NanoSIMS

Keywords confocal, multiphoton microscopy, electron microscopy, cryomicroscopy, tomography, nanoSIMS, videomicroscopy Contact Claude PRIGENT

Faculté de médecine 2 avenue du Pr Léon Bernard 35043 RENNES FRANCE Tel. +33(0)2 23 23 47 31 Fax: +33(0)2 23 23 44 78 [email protected] http://microscopie.univ-rennes1.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2008

BUSINESS SECTOR

53

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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ONIS Observatoire

national d'imagerie scientifique

MARKET RESEARCH

Description of services ONIS is a high-performance, multi-scale analytical imaging platform. Its equipment can visualise the chemical composition point by point in a tissue, a polymer, a soil sample, an insect, a plant or a lichen, etc., from the millimeter scale to the nanometer scale.

The facility offers imaging and elemental analysis services, personalized customer support services and protocol design, testing and image analysis and processing. ONIS also offers face-to-face training or e-training. Keywords analytical imaging, spectroscopy, spectrometry, NanoSIMS and RAMAN, fluorescence imaging, 2D/3D imaging, TEM, micrometer and nanometer techniques Contact Olivier LAVASTRE

UMR CNRS 6226 Campus de Beaulieu 263 avenue du Général Leclerc CS 74205 35042 RENNES CEDEX FRANCE Tel. +33(0)2 23 23 56 30 [email protected]

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2005

BUSINESS SECTOR

54

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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PIXEL Plate-forme d'imagerie

multi(X)photonique etendue large bande

MARKET RESEARCH

Description of services PIXEL is a fluorescence and harmonic photon microscopy facility which provides the scientific community with modern, high-performance tools for the five-dimensional functional, spatial and time-domain investigation (x, y, z, λ and t) of biological material.

The platform has two scanning light microscopes fitted with pulsed laser sources. This notably enables the analysis of biological samples to a depth of up to 1 mm, at the limits of multiphoton microscopy. In harmonic modes, multiphoton microscopy enables the in situ imaging of a number of hyperpolarizable molecules (collagen, myosin, tubulin, starch, cellulose, etc.). Keywords multiphoton imaging, confocal and harmonic microscopy Contact François TIAHO

Campus Beaulieu Bât.13, pièce 246 263 avenue du Général Leclerc 35042 RENNES CEDEX FRANCE Tel. +33(0)2 23 23 57 18 [email protected] http://pixel.univ-rennes1.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2005

BUSINESS SECTOR

55

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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POLARIS

MARKET RESEARCH

Description of services Polaris is a specialist provider of nutritional and functional lipids. The company offers a full range of omega-3-rich fish oils and omega-6-rich plant oils. The company's specific expertise in lipid chemistry and the stabilization of these polyunsaturated fatty acid-rich oils means that it can supply these products in several pharmaceutical formulations: liquids, powders (microcapsules), gels, emulsions and capsules.

For powder formulations, Polaris can microencapsulate plant-, animal- or mineral-derived raw materials. Its technological innovations enable a high active compound concentration, maximum protection, taste and odour masking and controlled release.

Polaris also performs new product formulation, trials, technical development and subcontracting.

Applications: formulation and stabilization of new molecules, new product development and trials in the field of polyunsaturated fatty acids, development for pharmaceuticals, nutraceuticals, health food, baby food, food supplements, agrifood, cosmetics, animal health and animal feed. Keywords lipid chemistry, microencapsulation, stabilisation, protection, antioxidants, natural oils, formulation, evaluation Contact Stéphane LOZACHMEUR

Chemin de Quilourin Moulin du Pont 29170 PLEUVEN FRANCE Tel. +33(0)2 98 54 84 20 Fax: +33(0)2 98 54 84 51 [email protected] www.polaris.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1994

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

56

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POLYMARISBIOTECHNOLOGY

MARKET RESEARCH

Description of services Polymaris Biotechnology is a specialist in the discovery, characterization and exploitation of novel marine biomolecules.

Our focus is on exopolysaccharides produced by bacteria from the company's private collection of marine micro-organisms (which currently contains over 500 isolates). From these Polymaris is currently developing more than ten entirely new, pure, fully-characterized molecules. It also offers custom hemi-synthesis using these molecules.

The target markets for the industrial application of these biodegradable, natural compounds are nutraceuticals, fine chemicals, the environment, agrifood, cosmetics, dermocosmetics and, in the longer term, healthcare. Keywords marine biomolecules, bacteria, exopolysaccharides Contact Anthony COURTOIS

Pépinière d’entreprises du pays de Morlaix Aéropôle centre 29600 MORLAIX FRANCE Tel. +33(0)2 98 88 04 57 Fax: +33(0)2 98 88 38 94 [email protected] www.polymaris.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2008

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

57

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PRISM Plate-forme

rennaise d'imagerie et de spectroscopie

structurale et métabolique

MARKET RESEARCH

Description of services PRISM offers a range of outstanding, well-matched methodological skills (imaging, spectroscopy, MRI, NMR and computed tomography) for the investigation of experimental models on the molecular scale (proteins and lipids), the cell level (bacteria, membranes, etc.), the tissue level (muscle and tumours), in the small animal (mice, rats, fishes and rabbits) and in larger animals (chickens, sheep and pigs).

PRISM has particular expertise in the following areas: • The biomedical sector: morphological and functional typing of

transgenic animals, dynamic studies of drug activity, the digestive impact of food product formulations and neurofunctional satiety studies

• Biology and agronomy: quantification of tissue distribution in animal and plant systems, membrane system studies, etc.

• Food science: ingredient and food product processability, water retention properties and storage stability testing

• Process engineering: mass and heat transfer analysis for bioproducts Keywords imaging, spectroscopy, MRI, NMR, tomography, scanner Contact François MARIETTE

Cemagref 17 avenue de Cucillé CS 64427 35044 RENNES CEDEX FRANCE Tel. +33(0)2 23 48 21 78 Fax: +33(0)2 23 48 21 15 [email protected] http://prism.univ-rennes1.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2003

BUSINESS SECTOR

58

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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PROCLAIM

MARKET RESEARCH

Description of services Proclaim is a contract research organization (CRO) which specializes in efficacy tests for cosmetics and nutritional products:

• Innovative tests, custom-designed trials and standard assays are used to evaluate ingredients and/or end products.

• In vitro assay methods (cultured fibroblasts, keratinocytes and adipocytes or human skin cultures, etc.)

• Performance of clinical studies in compliance with GLP and the legislation on biomedical research

Trials on healthy volunteers for marketing, scientific or regulatory purposes are performed in compliance with current quality and ethical standards. Keywords cosmetic products, food supplements, in vitro testing, trials on healthy volunteers, clinical trials Contact Dominique DE JAVEL et GUILLOU Sonia

Parc d’affaires de la Brétèche Bât. B1 35760 SAINT-GREGOIRE FRANCE Tel. +33(0)2 23 25 02 02 Fax: +33(0)2 23 25 29 74 [email protected] www.proclaim.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1999

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

59

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PRODIABIO

MARKET RESEARCH

Description of services The Prodiabio facility focuses on waste & effluent treatment and the exploitation of industrial co-products (methanization, biodigestion, etc.).

Cooking trials and food product formulation can be performed in the agrifood process suite and the associated sensorial analysis unit.

Prodiabio's skills in liquid and solid biofuels (boilers, stoves, etc.), mechanical engineering, automation and maintenance enable it to meet the needs of industrial businesses, local authorities and farm managers. Keywords process, environmental diagnosis, bioresources Contact Olivier SIRE

Allée des Pommiers 56300 PONTIVY FRANCE Tel. +33(0)2 97 27 67 70 Fax: +33(0)2 97 27 81 53 [email protected] www.pft-prodiabio.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2005

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

60

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SAFECOS associates

MARKET RESEARCH

Description of services Safecos associates provides expertise in toxicology and consultancy on safety testing. Our services include:

• Toxicological profiling • Health testing of cosmetic products in compliance with European Union

regulation 1223/2009 • Specific expertise in cosmetic products for children under the age of 3 • File audits for cosmetic products • Evaluation of CAM processes • Regulatory affairs support and consultancy

Keywords consultancy, cosmetics, toxicological profiling, regulatory compliance, safety testing Contact Dominique de JAVEL

Parc d’affaires de la Bretèche Bâtiment B1 35760 SAINT-GREGOIRE FRANCE Tel. +33(0)2 99 23 68 30 Fax: +33(0)2 23 25 29 74 [email protected] www.safecos.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1999

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

61

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SCIENCE ET MER

MARKET RESEARCH

Description of services For over 20 years, Science et Mer has been exploiting the particularly abundant seaweed resources on Brittany's northern coast. The company is now a leader in the development of products containing marine-based ingredients and has deployed its expertise in two main areas:

• The custom manufacturing of health and beauty products • Supplying thalassotherapy centres, spas and clinics with frequently

used products, such as seaweed powders, marine mud and poultices

The company produces a number of marine-based ingredients in-house using biotechnological processes. Science et Mer's mission is to provide its customers with high-quality services in several areas of expertise:

• Cosmetic formulation: creating new formulations and testing their stability, skin tolerance and efficacy and handling regulatory requirements

• Bulk manufacture • Packaging: choice of packaging and appropriate graphic design for

well-defined overall concepts • Finished product assembly and packaging

Keywords marine-based ingredients, manufacturing Contact Didier LE TANNOUR

BP 50 Venelle du Carros 29480 LE RELECQ KERHUON FRANCE Tel. +33(0)2 98 28 34 29 Fax: +33(0)2 98 28 40 32 [email protected] www.scienceetmer.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1986

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

62

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SEADEV FERMENSYS

MARKET RESEARCH

Description of services Seadev-Fermensys is the exclusive provider of extremophile marine bacteria collections, including Ifremer’s marine hydrothermophilic strains commercialized under an exclusive trade license.

Our two development sites (each with integrated research platforms) offer a comprehensive range of services for the screening, development and industrialization of novel natural compounds and innovative bioprocesses.

Seadev-Fermensys offers the sub-contracting of fermentation processes, bioconversions, process optimization, bioremediation and biopolymer screening. The company can also meet your demand in biomass production (fungi, bacteria, yeasts, non-GMOs), industrial feasibility and scale-up studies. Keywords strain library, biopolymers, fermentation, bioconversion, marine biotechnology, bioremediation, screening, industrial production, exopolysaccharides, bioplastics Contact Pierre-Jacques DAUNEAU

185 rue René Descartes Technopôle Brest Iroise 29280 PLOUZANE FRANCE Tel. +33(0)2 98 49 85 97 Fax: +33(0)2 98 49 85 96 [email protected] www.seadev-fermensys.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2004

BUSINESS SECTOR

63

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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Sequencing/ genotyping

core facility

MARKET RESEARCH

Description of services This core facility offers R&D services in sequencing and genotyping, from mid- to high-throughput, including:

• EST analysis • Pyrosequencing and de novo sequencing • Diversity • Environmental and functional genomics • Polymorphism analysis • Physical and genetic chromosome mapping • Positional cloning • Identification of genetic determinants • Diagnostic tools • Genetics of biodiversity

Keywords sequencing, genotyping, DNA extraction, DNA purification Contact Erwan CORRE

Station Biologique CNRS FR 2424 Place Georges Teissier BP 74 29682 Roscoff cedex FRANCE Tel. +33(0)2 98 29 23 81 Fax. +33(0)2 98 29 23 24 [email protected] www.sb-roscoff.fr/SG

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2002

BUSINESS SECTOR

64

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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STEPP Station technique d’expérimentation des plantes en pot

MARKET RESEARCH

Description of services STEPP Bretagne is a not-for-profit organization which specializes in pot plant and bedding plant trials.

In response to requests from its members, STEPP Bretagne sets up and monitors trials at its field station.

The field station's three main activities are: • The improvement of crop management techniques and the optimization

of pot plant and bedding plant production • Expansion of the range of pot/bedding plants and diversification of their

uses • The reduction of chemical inputs

Keywords horticulture, trials, applied research, development Contact Oscar STAPEL

Ecole d’horticulture de Saint-Ilan 52 rue de Saint-Ilan 22360 LANGUEUX FRANCE Tel. +33(0)2 96 52 47 13 Fax: +33(0)2 96 52 07 16 [email protected] www.astredhor.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1995

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

65

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SynNanoVect Plate-forme de production de nanovecteurs synthétiques

MARKET RESEARCH

Description of services The SynNanoVect core facility develops, optimizes and tests synthetic nanocarriers for the delivery of nucleic acids (DNA and siRNA) and biomolecules of interest.

The core facility offers several products and services: • Design and development of synthetic nanocarriers • Nanocarrier formulation • Physical-chemical characterization • Delivery efficiency measurements • Pre-clinical safety testing • Transgene constructs

The facility's chemistry lab specializes in vector synthesis and characterization. The biology lab offers a wide range of in vitro and in vivo models and various items of equipment for the in vivo assessment of nanocarrier efficacy, toxicity and inflammation parameters. Keywords biotherapy, gene and drug delivery, synthetic vectors, in vivo imaging assays, formulation, characterization Contact Tristan MONTIER

Unité INSERM 613 Bâtiment 2bis Hôpital Morvan 5 avenue du Maréchal Foch 29200 BREST FRANCE Tel. +33(0)2 98 01 80 80 Fax: +33(0)2 98 01 83 42 [email protected] http://ouest-genopole.org/index.php?pa=N342&Ia=fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2003

BUSINESS SECTOR

66

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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VEGENOV

MARKET RESEARCH

Description of services Vegenov (BBV) provides its customers with the benefit of over 20 years of experience in plant biotechnology, disease diagnosis and sensorial and nutritional analysis. It offers the following services:

• Creation of new plant varieties: haplomethods, embryo rescue, marker-aided selection, genetic distance estimation, resistance tests, etc.

• Crop protection: evaluation of phytosanitary products, disinfectants and natural defence elicitors, alternative crop protection approaches, pathogen detection

• Identification and traceability: genotyping (genetic fingerprinting) for checking genetic purity, detecting fraud and resolving legal disputes, etc.

• Improvement of seedlings and stock plants • Product quality: exploitation of nutritional assets and sensorial qualities • Project support: expert market and technology analysis, project set-up

and coordination, training. Keywords biotechnology, plant diseases, creation of new varieties, quality, sensorial evaluation, expert analysis, training, consultancy Contact Serge MABEAU

Penn Ar Prat 29250 SAINT-POL DE LEON FRANCE Tel. +33(0)2 98 29 06 44 Fax: +33(0)2 98 69 24 26 [email protected] www.vegenov.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1989

BUSINESS SECTOR

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

67

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VOISIN CONSULTING

MARKET RESEARCH

Description of services Voisin Consulting advises biomedical, biotech and pharmaceutical companies (including start-ups) on the design and implementation of their global regulatory strategy. Emphasis is placed on Europe/USA harmonization.

Voisin Consulting offers services ranging from the definition and implementation of a regulatory strategy for the initial stages of product development through to the clinical phases and then the preparation, assembly and submission of market authorization/CE mark applications. Keywords consulting, regulatory strategy Contact Anne DUPRAZ-POISEAU

Espace Performance Bâtiment J 35769 SAINT-GREGOIRE FRANCE Tel. +33(0)2 23 25 07 68 Fax: +33(0)2 23 25 27 98 [email protected] www.voisinconsulting.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

BUSINESS SECTOR

68

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

ESTABLISHED IN 1997

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XENOBLIS

MARKET RESEARCH

Description of services Xenoblis provides preclinical contract testing services for the evaluation of ADME, toxicity and pharmacokinetic properties of drug candidates.

The company performs screening, mechanistic studies and GLP-compliant regulatory studies and its expertise extends into in vitro models.

Xenoblis has developed a set of services for drug interaction modelling (inhibition and induction), drug clearance, metabolic stability, metabolic profiling, inter-species comparison and influx/efflux transporter assays. It has also developed (i) drug permeability assays for the digestive tract, the skin and the blood-brain barrier and (ii) techniques for characterizing drug-plasma protein interactions.

Assay turnaround times are optimized by the use of liquid chromatography-mass spectrometry (LC-MS/MS) and direct access to a biological resource collection comprising animal and human tissues and cells (hepatocytes, microsomes, plasma, skin, brain endothelial cells, etc.). Keywords pharmacokinetics, toxicology, in vitro assays, ADME, drug-drug toxicity, interactions study Contact Françoise BREE

Parc d’Affaires de la Bretèche Bâtiment B1 35760 SAINT-GREGOIRE FRANCE Tel. +33(0)2 99 23 77 77 Fax: +33(0)2 23 25 29 74 [email protected] www.xenoblis.com

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 1987

BUSINESS SECTOR

69

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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XENOPUS biological

resource center

MARKET RESEARCH

Description of services The ISO 9001-certified Xenopus biological resource center offers access to its expertise in Xenopus breeding, production and transgenesis:

• Sale and supply of Xenopus frogs and Xenopus oocytes expressing proteins of interest

• Use of the Xenopus model in research • Creation of transgenic Xenopus carrying a promoter linked to a

fluorescent protein or another protein of interest • Testing of homologous or heterologous promoters • Gene-trap mutagenesis and the supply of mutants of interest • Training in Xenopus breeding and in vitro fertilization techniques

Keywords embryology, developmental biology, cell biology, pharmacology, ecotoxicology Contact Thierry MADIGOU Campus de Beaulieu Bât. 13 263 avenue du Général Leclerc 35042 RENNES CEDEX FRANCE Tel. +33(0)2 23 23 68 89 Fax: +33(0)2 23 23 50 52 [email protected] http://xenopus.univ-rennes1.fr

BIOPRODUCTION

SCREENING

INTELLECTUAL PROPERTY

CHARACTERIZATION

VALIDATION

FORMULATION

REGULATORY & REGISTRATION

MARKETING

TYPE OF STRUCTURE

ESTABLISHED IN 2003

BUSINESS SECTOR

70

ENTERPRISE

TECHNICAL CORE FACILITY

TECHNOLOGICAL CENTER

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FROM MOLECULE TO MARKET

DIAGNOSTICS

MOLECULAR FARMING

CRITT Santé Bretagne wishes to particularly thank:

• CBB Développement, the tech transfer center for biotech and fine chemistry, provided valuable data and access to the structures involved in bioproduction.

Support Actors This catalog was made possible by CRITT Santé Bretagne and the support of many regional actors.

• The members of the Bioservices steering committee:

Pierrick AUVRAY - C.RIS Pharma, Jean-Erik BLOCHET - Zoopôle Développement, Arnaud DEVILLEZ - Bretagne Valorisation, Véronique LEMONON - Pays de Morlaix, Nathalie LETACONNOUX - CBB Développement Céline QUERON - Biogenouest.

For more information about the Capbiotek initiativeCapbiotekContact: Jacques DE [email protected]

For more information about molecular farming and bioproductionCBB DéveloppementContact: Gilbert BLANCHARDgilbert.blanchard@cbb-developpement.comwww.cbb-developpement.com

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For more information about the Bretagne bioservicesdirectory 2010CRITT Santé BretagneContact:Brian [email protected]

Jocelyne LE [email protected]

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