ART COMPLETES VOLUME 76 (1960)MBER 1960, VOLUME 76, No. 3

THE

BWIOCAHDEMICAL

rE. .S.D AONE . ATE

JOURNALEditedfor

THE BIOCHEMICAL SOCIETY

E. PC.ABAHAM C. H. GRAYecrct Edtothe B-oard..

W. N. ALDRIDGE D. C. HARRISON.-! J S. D. BACON E. F. HARTREE A

W. BARTLEY J. LASCELLES ¢ut

BTK.BURTON J. MANDELSTAMN

AMERICE. A. DAWESL3 W. MAPSON, ~R. M. C. DAWSON J. J. SCOTT

r' Secretaf ~to the Board:J* .'CLAkK

'V l /i'V-;-

CAMBRIDGE UNIVERSIlTY PRESSBENTLEY HOUSE, 200 EUSTON ROAD, LONDON, N.W.l

'4AMERICAN BRANCH: 32 EAST 57TH STREET, NEW YORK 22, N.Y.

- -0 :a0;:AF. O AC;

, ~~Edftedfoor ;; .. -

OHTHEBIOECH>£M7CC-lETY

Edi1torial Board

V.THORPE _-(Chafn) ;H. ROGERS (Dep*

E.P.1ABRAHAM GRAY

W.'N ALDRIDGE D. C. HARRISON

J. S.D. BACON Es P. HARTREEW. BARTLEY 1' LASCELLES

K.BlBURTON - ;. MANDELSTAM-E A. DAWES L. W. MAPSON

R M. C. DAWSON.. 3.1. SCOlTSectam to the BoaJ:F.CLARK

CAMBRI-DGE -UNIVER_SITY, PRESS'

BENTLEY HOUSE, 200 EUSTON ROAD, LONDON, N.W. I

AMERICAN BRANCH: 32 EAST 57TH STREET, NEW YORK 22, N.Y

Price 6d.inet

(U.S.A. 50 cents)

I

r

Vol. 76

Index of Authors

Note. Pages in Proceedings of The Biochemical Society are

ABOU AKKADA, A. R. & HOWARD, B. H. The biochemistryof rumen protozoa. 3. The carbohydrate metabolism ofEntodinium 445

ACLAND, J. D. & JOHNSON, S. Transport of iodide by thesmall intestine of the rat in vitro 19P

ADAMS, J. B. The biosynthesis of chondroitin sulphate.Incorporation of sulphate into chondroitin sulphate inembryonic chick cartilage 520

ALBERT, A. & SERJEANT, E. P. Quantitative studies of theavidity ofnaturally occurring substances for trace metals.4. A potentiometric method for highly insoluble com-plexes, and its application to complexes of adenine anion621

ALCOCK, N. & MACINTYRE, I. Interrelation of calcium andmagnesium absorption 19P

ALDRIDGE, W. N. & PARKER, V. H. Barbiturates andoxidative phosphorylation 47

ALEXANDER, W. D. see BISSET, S. K. 20PAMOORE, J. E. Exchange of potassium ions across a con-

centration difference by isolated rat-liver mitochondria438

ANDERSON, A. J. The presence of sialic acid in humancartilage 53 P

ANDERSON, A. J., LEPPER, M. H. & WINZLER, R. J. Theseparation of urine colloids on diethylaminoethyl-cellulose 10P

ANSELL, G. B. & BAYLISS, B. J. The cytidine diphosphatecholine content of brain tissue 20P

ANTONINI, E. & GIBSON, Q. H. Some observations on thekinetics of the reactions with gases of natural and re-constituted haemoglobins 534

ARBUTHNOTT, J. P., BAUcHOP, T. & DAWES, E. A. A elasticfission of pyruvic acid in Zymosarcina ventriculi 12P

ARMSTRONG, J. J., BADDILEY, J. & BUCHANAN, J. G. Struc-ture of the ribitol teichoic acid from the walls of Bacillussubtilis 610

ARNSTEIN, H. R. V., ARTMAN, M., MORRIS, D. & TOMS,E. J. Sulphur-containing amino acids and peptides inthe mycelium of Penicillium chrysogenum 353

ARNSTEIN, H. R. V. & MORRIS, D. Synthesis of opticalisomers of cystinylvaline 318

ARNSTEIN, H. R. V. & MORRIS, D. The structure of a pep-tide, containing ac-aminoadipic acid, cystine and valine,present in the mycelium of Penicillium chrysogenum 357

ARNSTEIN, H. R. V. & MORRIS, D. The utilization of L-eystinyl-L-valine for penicillin biosynthesis 323

ARNSTEIN, H. R. V. see also WOLFF, E. C. 375ARRHENIUS, E. see HULTIN, T. 109ARTMAN, M. see ARNSTEIN, H. R. V. 353AsHBY, D. R. see KODICEK, E. 14p, 15PAUDA, B. M. see KORZENOVSKY, M. 238AUSTRIAN, R. see MILLS, G. T. 31 PAVEs, E. K. see CHAYEN, J. 14PAvI-DoR, Y. A study of the effect of particle-bound y-

glutamyltranspeptidase on the product of interaction offluoropyruvate with glutathione 370

BADDILEY, J. see ARMSTRONG, J. J. 610BACHRACH, U., PERSKY, S. & RAZIN, S. Metabolism of

amines. 2. The oxidation ofnatural polyamines by Myco-bacterium smeqmnatis 306

BAILEY, K. & WORBOYS, B. D. The lamellibranch crystal-line style 487

BAINES, N. J. see ELMORE, D. T. 25P

BALAKRISHNAN, S. & RODNIGHT, a ugate ofindolyl-3-carboxylic acid 61 P

BALAZS, R. & RICHTER, D. Restriction of the availabilityof particle-bound nucleotides as a controlling mechanismof glucose metabolism 67 P

BALDWIN, B. C., ROBINSON, D. & WILLIAMS, R. T. Studiesin detoxication. 82. The fate of benzoic acid in somedomestic and other birds 595

BALDWIN, B. C., ROBINSON, D. & WILLIAMS, R. T. Studiesin detoxication. 83. The aromatization of cyclohexane-carboxylic acid in hens 600

BANERJEE, R. see ZELLER, E. A. 49PBARNABEI, 0. see TRIA, E. 36PBARON, D. N. see WILLIAMS, D. C. 37PBARTLEY, W. see BELLAMY, D. 78; BIRT, L. M. 328, 427BAUcHOP, T. see ARBUTHNOTT, J. P. 12PBAUER, SH. see MEYER, H. 27BAYLISS, B. J. see ANSELL, G. B. 20PBEEVERS, H. see BuTT, V. S. 51 PBELLAMY, D. & BARTLEY, W. The effect of the incubation

conditions on the respiration of mitochondria 78BENDALL, D. S., RANSON, S. L. & WALKER, D. A. Effects

of carbon dioxide on the oxidation of succinate and re-duced diphosphopyridine nucleotide by Ricinus mito-chondria 221

BENDALL, F. see HILL, R. 47PBERNHEIMER, H. P. see MILLS, G. T. 31 PBHEEMESWAR, B. see FAULKNER, P. 71BINES, B. J. & WHELAN, W. J. The mechanism of carbo-hydrase action. 6. Structure of a salivary oc-amylase limitdextrin from amylopectin 253

BIRMINGHAM, M. K. see WARD, P. J. 269BIRT, L. M. & BARTLEY, W. The behaviour of pyridine

nucleotides of mitochondria in a 'saline medium' 328BIRT, L. M. & BARTLEY, W. The pyridine nucleotidemetabolism of mitochondria incubated with and withoutadded substrates and metabolic inhibitors 427

BISSET, S. K., ALEXANDER, W. D. & CROOKS, J. The oxvgenconsumption of circulating human leucocytes after intra-venous injection of tri-iodothyroacetic acid and tri-iodothyronine 20P

BOOTH, V. H. & CONSTABLE, B. J. Stability of ascorbic acidin extracts of iris leaves 206

BORREBAOK, B. see WALAAS, 0. 68PBORST, P. & COLPA-BOONSTRA, J. P. The pyridine nucleo-

tide content of mitochondria of Ehrlich ascites tumourcells 60P

BOURKE, A. see LONGMUIR, I. S. 225BOWES, J. H., Moss, J. A. & RAISTRICK, A. S. The action of

y-rays on collagen 21 PBOYLAND, E. & WILLIAMS, K. The bioclhemistry of aro-

matic amines. 7. The enzymic hydrolysis of anmino-naphthyl glucosiduronic acids 388

BRAITHWAITE, G. D. & GoODWIN, T. W. Studies in carn-tenogenesis. 25. The incorporation of [1-_4C]acetate,[2-14C]acetate and 14CO2 into lycopene by tomato slies I

BRAITHWAITE, G. D. & GOODWIN. T. W. StUdies in caro-tenogenesis. 26. The incorporation of ['4C]acetate,['4C]mevalonate and '4CO2 into s-carotene by the fungusPhycomyces blakesleeanus 5

BRAITHWAITE, G. D. & GOODWIN, T. W. Studies in caro-tenogenesis. 27. Incorporation of [2-14C]acetate, DL-[2-'4C]mevalonate and 14C02 into carrot-root prepara-tions 194

Bioch. 1960, 76

INDEX OF AUTHORSBROADHEAD, G. D. & KILPATRICK, R. Metabolism of

2[35SJ-thiohydantoin and 5-carboxymethyl-2[35S]-thio-hydantoin 63P

BUCHANAN, J. G. see ARMSTRONG, J. J. 610BUJARD, E. see HANDWERCRE -Y. 54PBuNNY4N, J. see DIPLOCK, A;T. 563BURION, R. H. & SMELLIE H. M. S. Ribonucleic acid

synthbsiN in extr of,mammalian cells 21PBURDON, R. H.1 & E R. M. S. Studies on the bio-

synthesis of ritJnucleic acid by particle-free extracts ofmammalian cells 2 p

BURKE, D. C. The purification of interferon 50PBUSH, I. E. & GALE, M. M. The direct chromatographic

estimation of urinary steroid sulphates IOPBUTLER, J. A. V. see COHN, P. 23PBUTT, V. S. & BEEVERS, H. Hexose metabolism in maize

roots 51 PBUTT, W. D. & LEES, H. The biochemistry of the nitrifying

organisms. 6. The effect of oxygen concentration on

nitrite oxidation in the presence of different inorganicions 425

BUXTON, R. W. see NIMOMIYA, H. 47P

CEcIL, R. The reaction of 2:2'-diaminodiethyl disulphide(cystamine) with sulphite at low pH 156

CECIL, R. & LOENING, U. E. The reaction of the disulphidegroups of insulin with sodium sulphite 146

CHADWICK, B. T. & WILKISON, J. H. Some aspects of themetabolism of 5-hydroxytryptamine 102

CHATTERJEE, G. C. 8ee CHATTERJEE, I. B. 279CHATTERJEE, I. B., CHATTERJEE, G. C., GHOSH, N.- C.,GHOSH, J. J. & GuHA, B. C. Biological synthesis of L-ascorbic acid in animal tissues: conversion of D-gluc-uronolactone and L-gulonolactone into L-ascorbic acid279

CHAYEN, J., CHAYEN, R. & AVEs, E. K. The extraction oflipid matter by formalin 14P

CRAYEN, R. see CHAYEN, J. 14rCHEN, Y. T. 8ee ISHIERWOOD, F. A. 157CLANCY, M. J. & WHELAN, W. J. The enzymic polymeriza-

tion of D-galactose 22PCLARKE, I. D. see RANSON, S. L. 216COCKNG, E. C. Some effects of chelating agents on roots oftomato seedlings 51P

COHEN, S. & FREEMAN, T. Metabolic heterogeneity ofhuman y-globulin 475

COHN, P., SIMSON, P. & BUTLER, J. A. V. The presence ofbasic proteins in ribonucleoproteins of rat liver 23P

COLLINS, 0. M. see STONER, H. B. 135COLPA-BOONSTRA, J. 8ee HOLTON, F. A. 179COLPA-BOONSTRA, J. P. see BORST, P. 60PCONSTABLE, B. J. 8ee BOOTH, V. H. 206CONTRACTOR, S. F. & PEARLMAN, W. H. [16-3H]Proges-

terone metabolism in advanced pregnancy and in oophor-ectomized-hysterectomized women: urinary ketonicmetabolites 36

CooK, E. R., THOMAS, D. P. PAGE & DINGLE, J. T. Studieson syno-vial tissue. 7. Concentrations of creatine andphoephocreatine in synovial tissue 120

CORNER, J. J. 8ee HARBORNE, J. B. 53PCOUCHMAN, K. see RoITT, I. M. 34PCRAWFORD, M. A. & MILNE, M. D. Renal-tissue citrate and

citrate excretion in the rat 23PCREASER, E. H. & SPENCER, J. H. A comparison of the

nucleie acids of rat liver and Novikoff hepatoma 171GROOK, E. M. 8ee WATTS, D. C. 7PCROOKS, J. see BIssET, S. K. 20PCROSS, M. J. 8ee GUEST, J. R. 396CRUIOKSHANK, E. M. 8ee KODICEK, E. 15PCUMMINs, J. T. & MCILWAN, H. Ionic movements with

electrical pulses in mammalian cerebral cortical tissue64P

1960DAGLEY, S. see TRIPPETT, S. 9PDALGARNO, L. & HIRD, F. J. R. Inereaso in the process of

accumulation of amino acids in carrot slices with pro-longed aerobic washing 209

DANIEL, M., DINGLE, J. T. & WEBB, M. The effect of cobalton the metabolism of rat-dermal fibroblasts in culture24P

DAVIDSON, F. M. The activation ofplasminogen bystaphylo-kinase: comparison with streptokinase 56

DAVIDSON, J. N. see WEISSMAN, S. M. 1 P, 26PDAWES, E. A. see ARBUTHNOTT, J. P. 12P; HAMILTON,W. A. 70P

DAWKINS, M. J R., JUDAH, J. D. & REES, K. R. Action ofchlorpromazine. 3. Mitochondrial adenosine triphos-phatase and the adenosine triphosphate-adenosine di-phosphate exchange 200

DAWSON, R. M. C. & DITTMER, J. C. The hydrolysis pro-ducts of triphosphoinositide B prepared from ox brain42P

DEEGAN, T. see RILEY, M. V. 41DILLER, E. R. see KORZENOVSKY, M. 238DINGLE, J. T. see COOK, E. R. 120; DANIEL, M.24P

DIPLOCK, A. T., GREEN, J., EDWIN, E. E. & BUNYAN, J.Studies on vitamin E. 4. The simultaneous determina-tions of tocopherols, ubiquinones and ubichromenols(substance SC) in animal tissues: a reconsideration of theKeilin-Hartree heart preparation 563

DITTMER, J. C. see DAWSON, R. M. C. 42PDONIACH, D. see RoITT, I. M. 34PDUNN, D. B., SMITH, J. D. & SIMPSON, M. V. The distribu-

tion of additional components in ribonucleic acid fromparticulate and soluble fractions of cells 24P

EDWIN, E. E. see DIPLOCK, A. T. 563ELLIOTT, D. F., LEWis, G. P. & HORTON, E. W. The

structure of bradykinin 16PELLIS, R. B., KEMP, P. & HAWTHORNE, J. N. The hydro-

lysis of ox-brain diphosphoinositide fractions 43PELMORE, D. T. & BAINES, N. J. Kinetics of the trypsin-

catalysed hydrolysis of synthetic substrates 25PENNOR, A. H. see ROSSITER, R. J. 603EVANS, W. A. L. & PAYNE, D. W. Carbohydrases in the

alimentary tract of the locust Schistocerca gregaria(Forsk.) 50P

EVANS, W. C. see RIBBONS, D. W. 310EVELYN, S. R., MAIHS, E. A. & RoUx, D. G. Condensed

tannins. 5. The oxidative condensation of (+ )-catechin23

EVELYN, S. R. see also Roux, D. G. 17

FARBER, E. & MAGEE, P. N. The probable alkylation ofliver ribonucleic acid by the hepatic carcinogens dimethyl-nitrosamine and ethionine 58 P

FAULKNER, P. & BHEEMESWAR, B. Studies on the bio-synthesis of proteins in the silkworm, Bombyx mori (L.)71

FESSLER, J. H. A structural function of mucopolysacchar-ide in connective tissue 124

FESSLER, J. H. Mode of action of testicular hyaluronidase132

FESSLER, J. H. Some properties of neutral-salt-solublecollagen. 1 452

FESSLER, J. H. Some properties of neutral-salt-solublecollagen. 2 463

FISHER, R. B. & ZACHARIAH, P. Determination of theinsulin-like activity of the A-chain of insulin. Addendumto: The reaction of the disulphide groups of insulin withsodium sulphite (Cecil, R. & Loening, U. E.) 155

FOGGITT, F. & KELLIE, A. E. Isolation of urinary steroidglucuronosides 62P

FREEMAN, T. see COHEN, S. 475

626

INDEX OF AUTHORSFULTON, J. D. & SMITH, P. J. C. Carbohydrate metabolism

in Spirochaeta recurrenti8. 1. The metabolism of spiro-chaetes in vivo and in vitro 491

FURMINGER, I. G. S. The reactions of bovine meromyosinswith antiserum to bovine myosin 12P

GAFFNEY, T. J. see ROSSITER, R. J. 603GALE, M. M. see BUSH, I. E. 10PGALLOWAY, B. 8ee MILLS, G. T. 31P; SMITH, E. E. B. 35PGAMMACK, D. B., HUEHNS, E. R., LEHMANN, H. & SHOOTER,

E. M. Starch-gel electrophoresis applied to the detectionof hybrid haemoglobins 55P

GARNER, R. J., JONES, H. G. & SANSOM, B. F. Fissionproducts and the dairy cow. 2. Some aspects of themetabolism of the alkaline-earth elements calcium,strontium and barium 572

GHOSH, J. J. see CHATTERJEE, I. B. 279GHOSH, N. C. see CHATTERJEE, I. B. 279GIBSON, Q. H., GREENWOOD, C. & MASSEY, V. Some kinetic

observations on a new preparation of cytochrome oxidase46P

GIBSON, Q. H. see also ANTONINI, E. 534GILLMAN, T. see GRANT, R. A. 412GOODWIN, T. W. & PHAGPOLNGARM, S. Studies in caroteno-

genesis. 28. The effect of illumination on carotenoid syn-thesis in French-bean (Phaseolus vulgaris) seedlings 197

GOODWIN, T. W. 8ee also BRAITHWAITE, G. D. 1, 5, 194GORE, M. B. R. see WILLAuMs, D. C. 37PGRANT, J. K. 8ee MONGKOLKUL, K. 46PGRANT, P. T. & SARGENT, J. R. Properties of L-E-glycero-

phosphate oxidase and its role in the respiration ofTrypanosoma rhod/esiense 229

GRANT, P. T. & SARGENT, J. R. The L-rL-glycerophosphatedehydrogenase component of an oxidase system presentin Trypano8oma rhodesiense 48P

GRANT, R. A., HATHORN, M. & GILLMAN, T. Chemicalchanges in rabbit aorta and ear cartilage induced bypapain and calciferol 412

GRAY, E. D. 8ee WEISSMAN, S. M. 26PGREEN, A. L. & HAUGHTON, T. M. The estimation ofmono-amine oxidase 44P

GREEN, J. 8ee DIPLOCK, A. T. 563GREENWOOD, C. see GIBSON, Q. H. 46PGREVILLE, G. D. & TAPLEY, D. F. Effects of phenyl-

mercuric acetateon the enzymic activityofL-myosin 49PGUEST, J. R. Inhibition of methionine synthesis in Escher-

ichia coli by analogues of cobalamin 405GUEST, J. R., HELLEINER, C. W., CROSS, M. J. & WOODS,D. D. Cobalamin and the synthesis of methionine byultrasonic extracts of Escherichia coli 396

GuHA, B. C. see CHATTEBJEE, I. B. 279

HAGEN, U. Metal linkages in the thymus nucleohistoneand their damage by X-irradiation 56P

HAGERMAN, D. see HOSOYA, N. 297HAMILTON, W. A. & DAWES, E. A. The nature ofthe diauxic

effect with glucose and organic acids in Pseudomonasaeruginosa 70P

HANCOcK, R. Reduction in oxidative activities of somebacteria during inhibition of growth by streptomycin69v

HANDWERCK, V., BUJARD, E. & MAURON, J. The reduc-tion of aromatic nitro groups during acid hydrolysis inthe presence of carbohydrates and its bearing on thecolorimetric determination of c-dinitrophenyl-lysine 54P

HARBORNE, J. B. & CORNER, J. J. The metabolism ofcinnamic acids and coumarins in higher plants 53 P

HATCH, M. D. & TURNER, J. F. A protein disulphidereductase from pea seeds 556

HATHORN, M. see GRANT, R. A. 412HAUGHTON, T. M. see GREEN, A. L. 44PHAWTHORNE, J. N. see ELLIS, R. B. 43P

HEALD, P. J. Partial purification of a brain phospho-protein attached to subcellular particles 56P

HEATH, D. F. see STONER, H. B. 135HEATLEY, N. G., SHEIKH, M. A. & TAYLOR, K. B. Some

experiments on intrinsic factor 342HEILBRONN, E. Effect of certain hydrazines and amines onmonoamine oxidase and some pyridoxal phosphate-requiring enzymes 45P

HELE, P. Some effects of glutathione on protamine-treatedamino acid-activating systems 59P

HELLEINER, C. W. see GUEST, J. R. 396HELLYER, G. C. 8ee WINTERINGHAM, F. P. W. 543HERS, H. G. Amylo-1:6-glucosidase activity in tissues of

children with glycogen-storage disease 69PHILL, R. & BENDALL, F. A comparison between photo-

synthetic triphosphopyridine nucleotide reductase fromChlorella and higher plants 47P

HrND, F. J. R. & SYMONS, R. H. The mechanism of ketone-body formation 25P

HIRD, F. J. R. see also DALGARNO, L. 209HOFMANN, T. On the mechanism of activation of tryp-

sinogen by Penicillium kinase 26PHOLTON, F. A. & COLPA-BoONSTRA, J. Spectrophotometric

observations relating to the oxidation-reduction poten-tial of cytochrome b in non-phosphorylating heart-muscleparticles 179

HORTON, E. W. see ELLIOTT, D. F. 16PHOSOYA, N., HAGERMAN, D. & VILLEE, C. Stimulation of

fatty acid synthesis by oestradiol in vitro 297HOWARD, B. H. see ABOu AKKADA, A. R. 445HUEHNS, E. R. see GAMMACK, D. B. 55PHUGGINS, A. K., MOSES, V. & SMITH, M. J. H. Effects of

salicylate and 2:4-dinitrophenol on the metabolism of[3-14C]pyruvate in isolated rat tissues 11P

HULTIN, T., ARRHENIUS, E., Low, H. & MAGEE, P. N.Toxic liver injury. Inhibition by dimethylnitrosamine ofincorporation of labelled amino acids into proteins of rat-liver preparations in vitro 109

ISHERWOOD, F. A., MAPSON, L. W. & CHEN, Y. T. Synthesisof L-ascorbic acid in rat-liver homogenates: conversion ofL-gulono- and L-galactono-y-lactone and the respectiveacids into L-ascorbic acid 157

JOCELYN, P. C. The effect of human-serum albumin on theoxidation of glutathione in human erythrocytes 6P

JOHNSON, S. see ACLAND, J. D. 19PJONES, H. G. see GARNER, R. J. 572JUDAR, J. D. see DAWKINS, M. J. R. 200JUVA, K. see KULONEN, E. 54P

KEECH, D. B. see QUAYLE, J. R. 3pKEKWICK, R. G. 0. Serum-cholinesterase activity in healthand in liver disease 420

KELLIE, A. E. 8ee FOGGITT, F. 62PKELUS, A. Serological classification of rabbit y-globulins

13PKELUS, A., MARRACK, J. R. & RICHARDS, C. B. Specificity

of the antigens of rabbit y-globulin, hydrolysed by papain13P

KEMP, P. see ELLIS, R. B. 43PKILPATRICK, R. see BROADHEAD, G. D. 63PKING, R. J. B. The demonstration of a 16-hydroxy steroid

dehydrogenase in rat kidney 7PKLEMPERER, H. G. Glucose breakdown in chick-embryo

cells infected with influenza virus 67PKODICEK, E. & ASHBY, D. R. The fate of physiological

doses of 14C-labelled vitamin D2 in normal and rachiticrats 14P

KODICEK, E., CRUICKSHANK, E. M. & ASHBY, D. R. Themetabolism of 14C-labelled vitamin D2 injected intra-cardially into rats 15r

40-2

Vol. 76 627

INDEX OF AUTHORSKODICEK, E. & WILSON, P. W. The isolation of niacytin,

the bound form of nicotinic acid 27PKOGUT, M. & LIGHTBOWN, J. W. Selective inhibition by

2-heptyl-4-hydroxyquinoline N-oxide of some peroxid-ative reactions catalysed by certain haemoproteins andby a flavoprotein 8P

KORNER, A. Amino acid incorporation into protein of iso-lated rat-liver ribosomes 28P

KORNER, A. Incorporation of radioactive amino acids intoserum albumin by isolated rat-liver ribosomes 59P

KORZENOVSKY, M., DILLER, E. R., MARSHALL, A. C. &AUDA, B. M. Manometric assay and properties of pan-creatic cholesterol esterase 238

KRATZER, F. H. see VOHRA, P. 37PKRISHNA MURTI, C. R. Action of streptomycin on Vibrio

cholerae 362KRISTANSEN, T. see WALAAS, 0. 68PKULoNEN, E., SALMI, A. & JuVA, K. Experiments on the

metabolism of collagen in lathyrism 54PKvEDER, S., MCISAAC, W. M. & PAGE, I. H. The metabolism

of N-acetyl-5-[ft-14C]methoxytryptamine 28PKvEDER, S. see also McIsAAc, W. M. 30P

LAMPORT, D. T. A. & NORTHCOTE, D. H. The use of tissuecultures for the study of plant-cell walls 52P

LAPRESLE, C. & WEBB, T. Study of a proteolytic enzymefrom rabbit spleen 538

LEABACK, D. H. & WALKER, P. G. The fluorimetric assayof N-acetyl-,-glucosaminidase 29P

LECADET, M. see WORK, E. 39PLEEs, H. see BUTT, W. D. 425LEHMANN, H. see GAMMACK, D. B. 55rLEPPER, M. H. 8ee ANDERSON, A. J. 10PLEVINE, W. G. Observations on hydroxyindole oxidases43P

LEWIN, S. A thermodynamic approach to the selectiveeffect of pH in competitive biosynthesis of proteins29P

LEWIN, S. Mechanism of the reduction of methylene bluein glucose-glycine-phosphate solutions 17P

LEWIN, S. Non-enzymic interaction of phosphate and glu-cose in aqueous solutions 17P

LEWIs, G. P. see ELLIOTT, D. F. 16PLIGHTBOWN, J. W. see KOGUT, M. 8PLINcOLN, G. J. see WHITE, I. G. 301LOw, H. see HULTIN, T. 109LOENING, U. E. 8ee CECIL, R. 146LONGMUIR, I. S. & BOURKE, A. The measurement of the

diffusion of oxygen through respiring tissue 225LUZZATI, V. see TIMASHEFF, S. N. 57P

McILwAIN, H. Characterization of constituents of bloodplasma and of the brain which restore excitability toisolated cerebral tissues 16P

MCILWAIN, H. see also CUMMiNs, J. T. 64P; WOLFE, L. S.65P

MACINTYRE, I. see ALCOCK, N. 19PMCISAAc, W. M., KVEDER, S. & PAGE, I. H. The metabol-

isnm of 5_[ft_14C]methoxytryptamine 30PMcISAAC, W. M. see also KvEDER, S. 28PMcKAY, M. A. see WINTERINGHAM, F. P. W. 543MCKENNA, J. & NORYMBERSKI, J. K. The extraction andmeasurement of urinary 17-oxo steroid hydrogen sul-

phates 60PMCKERNAN, W. M. & RICKETTS, C. R. A basic derivative of

dextran and its interaction with serum albumin 117MAGAR, N. G. see PATIL, V. S. 417MAGEE, P. N. see FARBER, E. 58P; HULTIN, T. 109MAIHS, E. A. see EVELYN, S. R. 23MANCHESTER, K. L. & YOUNG, F. G. Promotion of growthand amino acid incorporation into protein of rats by anon-diabetogenic derivative of alloxan 68P

MANN, P. J. G. Further purification and properties of theamine oxidase of pea seedlings 44P

MAPSON, L. W. see ISHERWOOD, F. A. 157MARRACK, J. R. see KELUS, A. 13PMARSHALL, A. C. see KORZENOVSKY, M. 238MARTIN, E. M. The effect of encephalomyocarditis virus

infection on the ribonucleic acid metabolism of Krebs IImouse ascites celis 30P

MASSEY, V. see GIBSON, Q. H. 46PMAURON, J. see HANDWERCK, V. 54PMEADOW, P. Effects ofpenicillin on a mutant of Escherichia

coli requiring diaminopimelic acid 8PMENNE, F. The urea metabolism of the heart 63PMEYER, H., PREISS, B. & BAUER, SH. The oxidation of

fatty acids by a particulate fraction from desert-locust(Schistocerca gregaria) thorax tissues 27

MICHAELIS, M. see NiMOMIYA, H. 47PMIETTINEN, J. K. & SAVIOJA, T. Soluble nucleotides of

baker's yeast 66PMILLs, G. T., SMITH, E. E. B., BERN:EEIMER, H. P., AuS-TRIN, R. & GALLOWAY, B. The pathway of formationof uridine diphosphogalacturonic acid in type XXXIIIpneumococci and its importance in the formation ofbinary capsulated type III-XXXIII pneumococci duringtransformation 31 P

MiLLs, G. T. see also SMITH, E. E. B. 35PMILNE, M. D. see CRAWFORD, M. A. 23PMONGKOLKUL, K. & GRANT, J. K. Effect of oestradiol-17,Bon the production of reduced triphosphopyridine nucleo-tide in the rat uterus 46P

MORRIs, D. Synthesis of the x- and y-isomers of glutamyl-cystinylvaline 349

MORRIS, D. see also ARNSTEIN, H. R. V. 318, 323, 353, 357MOSES, V. & SMITH, M. J. H. Uncoupling reagents and

metabolism. 2. Effects of 2:4-dinitrophenol and sali-cylate on glucose metabolism in baker's yeast 585

MosEs,V. see also HUGGINs, A.K. 11P; SMITH,M.J. H. 579Moss, D. W. Kinetics of phosphatase action on naphthyl

phosphates, determined by a highly sensitive spectro-fluorimetric technique 32P

Moss, J. A. see BowEs, J. H. 21P

NEEDHAM, D. M. see WAKID, N. W. 95NINOMIYA, H., BUXTON, R. W. & MICHAELIS, M. Reduc-

tases, glycolysis and protein content of rat brain aftershock with and without tranquillization 47P

NORTHCOTE, D. H. see LAMPORT, D. T. A. 52PNORYMBERSKI, J. K. see MCKENNA, J. 60P

PACHA, W. L. see ZELLER, E. A. 45PPAGE, I. H. see KVEDER, S. 28P; McIsAAc, W. M. 30rPARKER, V. H. see ALDRIDGE, W. N. 47PATIL, V. S. & MAGAR, N. G. Effect of dietary fat intakeand age on polyunsaturated fatty acids in human-bloodserum 417

PATTERSON, D. S. P. The isolation of coproporphyrin IIIfrom Mycobacterium tuberculosis avium 189

PAUL, J. see WEISSMAN, S. M. 1PPAYNE, D. W. see EVANS, W. A. L. 50PPEARLMAN, W. H. see CONTRACTOR, S. F. 36PEEL, D. 8ee QUAYLE, J. R. 3PPERKiNS, H. R. see RICHMOND, M. H. 1PPERSKY, S. see BACHRACH, U. 306PETERS, R. A. Fluorine compounds in African plants 32?PHAGPOLNGARM, S. 8ee GOODWIN, T. W. 197PREISS, B. see MEYER, H. 27PRIDHAM, J. B. Oligosaccharides and associated glyco-

sidases in aspen tissues 13PROCTOR, M. H. Nucleic acid turnover and enzyme syn-

thesis in resting bacteria 57PPROCTOR, M. H. & SCHER, S. Decomposition of benzoate bya photosynthetic bacterium 33P

628 1960

INDEX OF AUTHORSPRUSOFF, W. H. Adenosine triphosphate and 5-hydroxy-

tryptamine in cytoplasmic particles of small intestine65P

PUMPHREY, A. M. & REDFEARN, E. R. A method fordetermining the concentration of ubiquinone in mito-chondrial preparations 61

PUMPHREY, A. M. see also REDFEARN, E. R. 64

QUAYLE, J. R., KEECH, D. B. & TAYLOR, G. A. Metabolismof oxalate in oxalate-grown Pseudomonas oxalaticus(OX 1) 3P

QUAYLE, J. R. & PEEL, D. Methanol and carbon dioxideincorporation by Pseudomonas sp. AM 1 3p

RABIN, B. R. Metal-peptide complexes and proteolyticenzymes 33P

RABIN, B. R. see also WATTS, D. C. 7PRAISTRICK, A. S. See BOWES, J. H. 21PRANSON, S. L., WALKER, D. A. & CLARKE, I. D. Effects of

carbon dioxide on mitochondrial enzymes from Ricinus216

RANSON, S. L. see also BENDALL, D. S. 221RAZIN, S. see BACHRACH, U. 306REDFEARN, E. R. & PuMpHREy, A. M. The kinetics of ubi-

quinone reactions in heart-muscle preparations 64REDFEARN, E. R. see also PUMPHREY, A. M. 61REES, K. R. see DAWKINS, M. J. R. 200RIBBONS, D. W. & EVANS, W. C. Oxidative metabolism of

phthalic acid by soil pseudomonads 310RICHARDS, C. B. see KELUS, A. 13PRIcHMOND, M. H. & PERKINS, H. R. Possible precursors for

the synthesis of muramic acid by Staphylococcus aureus524 1 p

RICHTER, D. see BALAzs, R. 67PRICKETTS, C. R. see McKERNAN, W. M. 117RIEY, M. V. & DEEGAN, T. The effect of Plasmodium

berghei malaria on mouse-liver mitochondria 41ROBERTS, P. J. P. & WHELAN, W. J. The mechanism

of carbohydrase action. 5. Action of human salivaryx-amylase on amylopectin and glycogen 246

ROBINSON, D. see BALDWIN, B. C. 595, 600RODNIGHT, R. see BALAKRISHNAN, S. 61PROITT, I. M., DONIACH, D. & COUCHMAN, K. Biochemical

studies of thyroid auto-antigens 34PROSENBERG, H. see ROSSITER, R. J. 603ROSSITER, R. J., GAFFNEY, T. J., ROSENBERG, H. & ENNOR,

A. H. The formation in vivo of lombricine in the earth-worm (Megascolides cameroni) 603

ROSSITER, R. J. see also STRICKLAND, K. P. 41 PRoux, D. G. & EVELYN, S. R. Condensed tannins. 4. The

distribution and deposition of tannins in the heartwoodsof Acacia mollissima and Schinopsis spp. 17

Roux, D. G. see also EVELYN, S. R. 23RowE, C. E. The phospholipids of human-blood plasmaand their exchange with the cells 471

RYLE, A. P. Gastric enzymes 34P

SALMI, A. see KULONEN, E. 54PSANSOM, B. F. see GARNER, R. J. 572SARGENT, J. R. see GRANT, P. T. 229, 48PSARKAR, S. see ZELLER, E. A. 45PSAVIOJA, T. see MIETTINEN, J. K. 66PSCHER, S. see PROCTOR, M. H. 33PSERJEANT, E. P. see ALBERT, A. 621SHEIKH, M. A. see HEATLEY, N. G. 342SHOCH, D. see ZELLER, E. A. 49PSHOOTER, E. M. see GAMMACK, D. B. 55PSIMPSON, M. V. see DUNN, D. B. 24PSIMSON, P. see COHN, P. 23PSLOANE-STANLEY, G. H. A sensitive method for the

selective estimation of long-chain acyl hydroxamates41 P

SMELLIE, R. M. S. see BURDON, R. H. 2P, 21P; WEISSMANS. M. lp, 26P

SMITH, E. E. B., GALLOWAY, B. & MILLS, G. T. The purifi-cation and composition of type I pneumococcal capsularpolysaccharide 35P

SMITH, E. E. B. see also MILLS, G. T. 31PSMITH, J. D. see DUNN, D. B. 24PSMITH, M. J. H. & MOSES, V. Uncoupling reagents and

metabolism. 1. Effects of salicylate and 2:4-dinitro-phenol on the incorporation of 14C from labelled glucoseand acetate into the soluble intermediates of isolated rattissues 579

SMITH, M. J. H. see also HUGGINS, A. K. lIP; MOSES, V.585

SMITH, P. J. C. Carbohydrate metabolism in Spirochaetarecurrentis. 2. Enzymes associated with disintegratedcells and extracts of spirochaetes 500

SMITH, P. J. C. Carbohydrate metabolism in Spirochaetarecurrentis. 3. Properties of aldolase in spirochaetes508

SMITH, P. J. C. Carbohydrate metabolism in Spirochaetarecurrentis. 4. Some properties of hexokinase and lacticdehydrogenase in spirochaetes 514

SMITH, P. J. C. see also FULTON, J. D. 491SPENCER, J. H. see CREASER, E. H. 171STONER, H. B., HEATH, D. F. & CoLLiNS, 0. M. The

metabolism of [14C]glucose, [14C]fructose and [2-14C]pyr-uvate after limb ischaemia in the rat 135

STOPHER, D. A. see TRIPPETT, S. 9PSTREET, H. V. Inhibition of amylase activity of humanbody fluids by citrate 10

STRICKLAND, K. P., THOMPSON, W., SUIBRAHMANYAM, D.& ROSSITER, R. J. Studies of the biosynthesis of braininositol phosphatide 41 P

SUBRAHMANYAM, D. see STRICKLAND, K. P. 41PSUBRAHMANYAM, K. Metabolism in the New Zealand strain

of obese mice 548SYMONS, R. H. see HIRD, F. J. R. 25P

TAPLEY, D. F. see GREVILLE, G. D. 49PTATA, J. R. The interaction ofthyroid hormones with intra-and extra-cellular proteins 35P

TAYLOR, G. A. see QUAYLE, J. R. 3PTAYLOR, K. B. see HEATLEY, N. G. 342TAYLOR, W. H. Aspects of the mechanism of action of

gastrointestinal proteinases 36 PTEALE, F. W. J. The ultraviolet fluorescence of proteins in

neutral solution 381THOMAS, D. P. PAGE, see COOK, E. R. 120THOMPSON, W. see STRICKLAND, K. P. 41 PTHOMSON, A. E. R. & YOUNG, L. Formation of N-acetyl-

S-ethyl-L-cysteine S-oxide from bromoethane in theanimal body 62P

THOMSON, R. Y. see WEISSMAN, S. M. lP, 26PTHORNE, C. J. R. A comparison of some malic dehydro-

genases 4P

TIMASHEFF, S. N. & LuZZATI, V. Low-angle X-ray-scattering studies of ribonucleic acid in solution 57 P

ToMs, E. J. see ARNSTEIN, H. R. V. 353TRIA, E. & BARNABEI, 0. Metabolic activities of a peptidyl-

phosphatide of liver 36PTRIPPETT, S., DAGLEY, S. & STOPHER, D. A. Bacterial

oxidation of protocatechuic acid 9PTUBBS, P. K. Some properties of mitochondrial D-a-hydroxy acid dehydrogenase 48P

TURNER, J. F. see HATCH, M. D. 556TYLER, D. B. Effect of citric acid-cycle intermediates on

oxaloacetate utilization and succinate oxidation 293

VILLEE, C. see HOSOYA, N. 297VOHRA, P. & KRATZER, F. H. Metabolism of DL-[2-14C]-

lysine in turkey poults 37P

Vol. 76 629

INDEX OF AUTHORSWAKID, N. W. Cytoplasmic fractions of rat myometrium.

1. General description and some enzymic properties88

WAKID, N. W. & NEEDHAM, D. M. Cytoplasmic fractions ofrat myometrium. 2. Localization of some cellular con-stituents in the pregnant and ovariectomized states95

WALAAS, E. see WALAAS, 0. 68PWALAAS, O., WALAAS, E., BORREBA;K, B. & KRISTIANSEN,

T. Insulin-stimulated incorporation of [14C]glucose intotwo glucose complexes of rat diaphragm 68P

WALKER, D. A. see BENDALL, D. S. 221; RANSON, S. L.216

WALKER, G. J. & WHELAN, W. J. The mechanism of carbo-hydrase action. 7. Stages in the salivary oc-amylolysis ofamylose, amylopectin and glycogen 257

WALKER, G. J. & WHELAN, W. J. The mechanism ofcarbohydrase action. 8. Structures of the muscle-phos-phorylase limit dextrins of glycogen and amylopectin264

WALKER, P. G. see LEABACK, D. H. 29PWARD, P. J. & BIRMINGHAM, M. K. Properties of the

ultraviolet-absorbing lipids produced by rat adrenals invitro 269

WATTS, D. C., RABIN, B. R. & CROOK, E. M. The thiolgroup in the 'active site' of creatine phosphokinase7P

WEBB, M. see DANIEL, M. 24PWEBB, T. see LAPRESLE, C. 538WEISSMAN, S. M., GRAY, E. D., THOMSON, R. Y., SMELLIE,

R. M. S. & DAVIDSON, J. N. Factors controlling theenzymic synthesis of deoxyribonucleic acid 26P

WEISSMAN, S. M., PAUL, J., THOMSON, R. Y., SMELLIE,R. M. S. & DAVIDSON, J. N. Thymidine kinases in mam-malian tissues 1 P

WHELAN, W. J. see BINES, B. J. 253; CLANCY, M. J. 22P;ROBERTS, P. J. P. 246; WALKER, G. J. 257, 264

WHITE, I. G. & LINCOLN, G. J. The yellow pigmentation ofbull semen and its content of riboflavin, niacin, thiamineand related compounds 301

WILKINSON, J. H. see CHADWICK, B. T. 102

WILLiAMS, D. C., BARON, D. N. & GORE, M. B. R. Andro-gens as activators of the pyridine nucleotide transhydro-genase in human and rat liver 37P

WILLIAMS, K. see BOYLAND, E. 388WILLIAMS, R. T. see BALDWIN, B. C. 595, 600WILSON, P. W. see KODICEK, E. 27PWIrNER, A. D. Fluorescent studies of ox-brain lactic and

malic dehydrogenase 5zPWINER, A. D. Purification and some kinetic properties of

ox-brain lactic and malic dehydrogenase 5PWINTERINGHAM, F. P. W., HELLYER, G. C. & MCKAY,M. A. Effects of the insecticides DDT and dieldrin onphosphorus metabolism of the adult housefly Muscadomestica L. 543

WINZLER, R. J. see ANDERSON, A. J. 10PWOLFE, L. S. & MCILWAIN, H. Migration of histones from

nuclei of isolated cerebral tissues kept in cold media 65PWOLFF, E. C. & ARNSTEIN, H. R. V. The metabolism of

6-aminopenicillanic acid and related compoumds byPenicillium chrysogenum and its possible significance forpenicillin biosynthesis 375

WOODS, D. D. see GUEST, J. R. 369WORBOYS, B. D. see BAILEY, K. 487WORK, E. Properties of A-endolysin, the lytic enzyme in

lysates of lysogenic Escherichia coli (A) 38PWORK, E. & LECADET, M. Digestion of cell walls of Escher-

ichia coli and Bacillus megaterium by A-endolysin or lyso-zyme 39 P

YouNG, F. G. see MANCHESTER, K. L. 68PYOUNG, L. see THOMSON, A. E. R. 62P

ZACHARIAH, P. see. FISHER, R. B. 155ZAHN, R. K. Deoxyribonucleases as growth substances66P

ZELLER, E. A., BANERJEE, R. & SHOCH, D. Enzymologyand comparative biochemistry of a new lens peptidase49P

ZELLER, E. A., PACHA, WV. L. & SARKAR, S. Further ex-ploration of the active centre of monoamine oxidases45P

630 1960

Vol. 76

Index of Subjects

Note. Pages in Proceedings of The Biochemical Society are distinguished by P

Acacia mollissima, distribution and deposition of tanninsin heartwood of (Roux, D. G. & Evelyn. S. R.) 17

[14C]Acetate, effect of salicylate and 2:4-dinitrophenol onincorporation of 14C from, into soluble intermediates ofrat tissues (Smith, M. J. H. & Moses, V.) 579

[14C]Acetate, incorporation of, into ,-carotene by the fungusPhycomyces blakesleeanus (Braithwaite, G. D. & Goodwin,T. W.) 5

[14C]Acetate, incorporation of, into lycopene by tomatoslices (Braithwaite, G. D. & Goodwin, T. W.) 1

[2-"4C]Acetate, incorporation of, into carrot-root prepara-tions (Braithwaite, G. D. & Goodwin, T. W.) 194

N-Acetyl-S-ethyl-L-cysteine S-oxide, formation of, frombromoethane in the animal body (Thomson, A. E. R. &Young, L.) 62 p

N-Acetyl-,-glucosaminidase, fluorimetric assay of (Lea-back, D. H. & Walker, P. G.) 29P

N-Acetyl-5-[,-14C]methoxytryptamine, metabolism of(Kveder, S., Mclsaac, W. M. & Page, I. H.) 28P

Acyl hydroxamates, long-chain, sensitive method for selec-tive estimation of (Sloane-Stanley, G. H.) 41 P

Adenine anion, a potentiometric method for determinationof stability constants of metal complexes and its applica-tion to complexes of (Albert, A. & Serjeant, E. P.)621

Adenosine triphosphatase, mitochondrial, action of chlor-promazine on (Dawkins, M. J. R., Judah, J. D. &Rees, K. R.) 200

Adenosine triphosphate in cytoplasmic particles of smallintestine (Prusoff, W. H.) 65P

Adenosine triphosphate-adenosine diphosphate exchange(Dawkins, M. J. R., Judah, J. D. & Rees, K. R.) 200

Adrenal gland, rat, properties of ultraviolet-absorbinglipids produced by, in vitro (Ward, P. J. & Birmingham,M. K.) 269

Age, effect of, on polyunsaturated fatty acids in human-blood serum (Patil, V. S. & Magar, N. G.) 417

D-Alanine, from hvdrolysis of ribitol teichoic acid (Arm-strong, J. J., Baddiley, J. & Buchanan, J. G.) 610

Albumin, human-serum, effect of, on oxidation of gluta-thione in humsn erythrocytes (Jocelyn, P. C.) 6P

Albumin, serum, basic derivative of dextran and its inter-action with (McKernan, W. M. & Ricketts, C. R.) 117

Albumin, serum, incorporation of radioactive amino acidsinto, by isolated rat-liver ribosomes (Korner, A.) 59P

Aldolase, properties of, in spirochaetes (Smith, P. J. C.)508

Aldosterone, recovery of, from lipids produced by ratadrenals in vitro (Ward, P. J. & Birmingham, M. K.) 269

Alimentary tract of locust, carbohydrases in (Evans,W. A. L. & Payne, D. W.) 50P

Alloxan, promotion ofgrowth and amino acid incorporationinto protein by a non-diabetogenic derivative of (Man-chester, K. L. & Young, F. G.) 68P

Amine oxidase of pea seedlings, further purification andproperties of (Mann, P. J. G.) 44P

Amines, effect of, on monoamine oxidase and some pyr-idoxal phosphate-requiring enzymes (Heilbronn, E.)45P

Amino acid incorporation into protein of isolated rat-liverribosomes (Korner, A.) 28P

Amino acid, promotion of incorporation of, into protein bya non-diabetogenic derivative of alloxan (Manchester,K. L. & Young, F. G.) 68P

Amino acids, increase in accumulation of, in carrot sliceswith prolonged aerobic washing (Dalgarno, L. & Hird,F. J. R.) 209

Amino acids, labelled, inhibition by dimethylnitrosamine ofincorporation of, into proteins of rat-liver preparations invitro (Hultin, T., Arrhenius, E., Low, H. & Magee, P. N.)109

Amino acids, radioactive, incorporation of, into serumalbumin by isolated rat-liver ribosomes (Korner, A.) 59P

Amino acids, sulphur-containing, in the mycelium ofPenicillium chrysogenum (Arnstein, H. R. V., Artman,M., Morris, D. & Toms, E. J.) 353

a-Aminoadipic acid, presence of, in peptide form in my-celium of Penicillium chry8olenum (Arnstein, H. R. V.,Artman, M., Morris, D. & Toms, E. J.) 353

8-(x-Aminoadipyl)cystinylvaline, occurrence of, in my-celium of Penicillium chrysogenum (Arnstein, H. R. V. &Morris, D.) 357

Aminonaphthyl glucosiduronic acids, enzymic hydrolysis of(Boyland, E. & Williams, K.) 388

6-Aminopenicillanic acid, metabolism of, by Penicilliumchrysogenum and its possible significance for penicillinbiosynthesis (Wolff, E. C. & Arnstein, H. R. V.) 375

Amylase activity of human body fluids, inhibition of, bycitrate (Street, H. V.) 10

a-Amylase limit dextrin, salivary, structure of, from amylo-pectin (Bines, B. J. & Whelan, W. J.) 253

cc-Amylase of Entodinium (Abou Akkada, A. R. & Howard,B. H.) 445

x-Amylase, salivary, human, action of, on amylopectin andglycogen (Roberts, P. J. P. & Whelan, W. J.) 246

Amylo-1:6-glucosidase activity in tissues of children withglycogen-storage disease (Hers, H. G.) 69P

Amylopectin, action of human salivary a-amylase on(Roberts, P. J. P. & Whelan, W. J.) 246

Amylopectin, stages in the salivary a-amylolysis of(Walker,G. J. & Whelan, W. J.) 257

Amylopectin, structure of a salivary oc-amylase limit dex-trin from (Bines, B. J. & Whelan, W. J.) 253

Amylopectin, structures of muscle-phosphorylase limitdextrins of (Walker, G. J. & Whelan, W. J.) 264

Amylose, stages in the salivary x-amylolysis of (Walker,G. J. & Whelan, W. J.) 257

Androgens as activators of pyridine nucleotide transhydro-genase in human and rat liver (Williams, D. C., Baron,D.N. &8Gore,M. B. R.) 37P

Aorta, rabbit, chemical changes in, induced by papain andcalciferol (Grant, R. A., Hathorn, M. & Gillman, T.)412

Ascites cells, mouse, Krebs II, effect of encephalomyocar-ditis-virus infection on the ribonucleic acid metabolismof (Martin, E. M.) 30P

Ascorbic acid, stability of, in extracts of iris leaves (Booth,V. H. & Constable, B. J.) 206

L-Ascorbic acid, conversion of D-glucuronolactone and L-gulonolactone into (Chatterjee, I. B., Chatterjee, G. C.,Ghosh, N. C., Ghosh, J. J. & Guha, B. C.) 279

L-Ascorbic acid, conversion of L-gulono- and L-galactono-y-lactone and the respective acids into (Isherwood, F. A.,Mapson, L. W. & Chen, Y. T.) 157

Aspen tissues, oligosaccharides and glycosidases in (Prid-ham, J. B.) 13

Azide, effect of, on mitochondrial adenosine triphosphatase(Dawkins, M. J. R., Judah, J. D. & Rees, K. R.) 200

631

INDEX OF SUBJECTSBacillus megaterium, digestion of cell walls of, by A-endo-

lysin or lysozyme (Work, E. & Lecadet, M.) 39PBacillus subtilis, structure of ribitol teichoic acid from walls

of (Armstrong, J. J., Baddiley, J. & Buchanan, J. G.)610

Bacteria, decrease in oxidative activities of, during inhibi-tion of growth by streptomycin (Hancock, R.) 69P

Bacteria, resting, nucleic acid turnover and enzyme syn-thesis in (Proctor, M. H.) 57 p

Barbiturates and oxidative phosphorylation (Aldridge,W. N. & Parker, V. H.) 47

Barium, some aspects of the metabolism of, in lactatingcows (Gamer, R. J., Jones, H. G. & Sansom, B. F.) 572

Benzoate, decomposition of, by a photosynthetic bacterium(Proctor. M. H. & Seher. S.) 33P

Benzoic acid, fate of, in birds (Baldwin, B. C., Robinson,D. & Williams, R. T.) 595

Benzoyl glucuronide, excretion of, by birds after feedingwith benzoic acid (Baldwin, B. C., Robinson, D. & Wil-liams, R. T.) 595

Benzoyl glucuronide, excretion of, by the hen after feedingwith cyclohexanecarboxylic acid (Baldwin, B. C., Robin-son, D. & Williams, R. T.) 600

Birds, fate of benzoic acid in (Baldwin, B. C., Robinson, D.& Williams, R. T.) 595

Blood plasma, human, phospholipids of, and their exchangewith the cells (Rowe, C. E.) 471

Blood serum, human, effect of dietary fat intake and ageon polyunsaturated fatty acids in (Patil, V. S. & Magar,N. G.) 417

Bombyx mori (L.), studies on biosynthesis of proteins in(Faulkner, P. & Bheemeswar, B.) 71

Bradykinin, structure of (Elliott, D. F., Lewis, G. P. &Horton, E. W.) 16P

Brain, characterization of constituents of blood plasma and,which restore excitability to isolated cerebral tissues(Mcllwain, H.) 16P

Brain inositol phosphatide, biosynthesis of (Strickland,K. P., Thomp3on, W., Subrahmanyam, D. & Rossiter,R. J.) 41 P

Brain, ox, fluorescent studies of lactic and malic dehydro-genase of (Winer, A. D.) 5P

Brain, ox, hydrolysis of diphosphoinositide fractions from(Ellis, R. B., Kemp, P. & Hawthorne, J. N.) 43P

Brain, ox, hydrolysis products of triphosphoinositide Bprepared from (Dawson, R. M. C. & Dittmer, J. C.) 42P

Brain, ox, purification and some kinetic properties of lacticand malic dehydrogenase of (Winer, A. D.) 5P

Brain phosphoprotein, partial purification of, attached tosubcellular particles (Heald, P. J.) 56P

Brain, rat, reductases, glycolysis and protein content of,after shock with and without tranquillization (Ninomiya,H., Buxton, R. W. & Michaelis, M.) 47P

Brain tissue, cytidine diphosphate choline content of(Ansell, G. B. & Bayliss, B. J.) 20P

Bromoethane, formation of N-acetyl-S-ethyl-L-cysteineS-oxide from, in the animal body (Thomson, A. E. R. &Young, L.) 62P

Calciferol, chemical changes in rabbit aorta and ear carti-lage induced by (Grant, R. A., Hathorn, M. & Giliman,T.) 412

Calcium and magnesium absorption, inter-relation of(Alcock, N. & Maclntyre, I.) 19P

Calcium, some aspects of the metabolism of, in lactatingcows (Garner, R. J., Jones, H. G. & Sansom, B. F.) 572

Carbohydrases in alimentary tract of locust (Evans,W. A. L. & Payne, D. W.) 50P

Carbohydrate metabolism of Entodinium (Abou Akkada,A. R. & Howard, B. H.) 445

Carbohydrate metabolism of spirochaetes in vivo and invitro (Fulton, J. D. & Smith, P. J. C.) 491

Carbohydrates, reduction of aromatic nitro groups duringacid hydrolysis in the presence of, and its bearing on thecolorimetric determination of E-dinitrophenyl-lysine(Handwerck, V., Bujard, E. & Mauron, J.) 54P

Carbon dioxide, effects of, on mitochondrial enzymes fromRicinus (Ranson, S. L., Walker, D. A. & Clarke, I. D.)216

Carbon dioxide, effects of, on the oxidation of succinateand reduced diphosphopyridine nucleotide by Ricinusmitochondria (Bendall, D. S., Ranson, S. L. & Walker,D. A.) 221

Carbon dioxide incorporation by Pseudomonas sp. AM 1(Quayle, J. R. & Peel, D.) 3P

Carbon dioxide, "4C-labelled, incorporation of, into B-caro-tene by the fungus Phycomyces blake8leeanus (Braith-waite, G. D. & Goodwin, T. W.) 5

Carbon dioxide, "4C-labelled, incorporation of, into carrot-root preparations (Braithwaite, G. D. & Goodwin, T. W.)194

Carbon dioxide, "4C-labelled, incorporation of, into lyco-pene by tomato slices (Braithwaite, G. D. & Goodwin,T. W.) 1

5-Carboxymethyl-2[35S]-thiohydantoin, metabolism of(Broadhead, G. D. & Kilpatrick, R.) 63P

,-Carotene, incorporation of [14C]acetate, ["4C]mevalonateand "4CO2 into, by the fungus Phycomyces blake8leeanuw(Braithwaite, G. D. & Goodwin, T. W.) 5

Carotenoid synthesis in French-bean (Phaeolus vulgaris)seedlings, effect of illumination on (Goodwin, T. W. &Phagpolngarm, S.) 197

Carrot slices, increase in accumulation of amino acids in,with prolonged aerobic washing (Dalgarno, L. & Hird,F. J. R.) 209

Carrot-root preparations, incorporation of [2-14C]acetate,DL-[2-14C]mevalonate and 14CO2 into (Braithwaite, G. D.& Goodwin, T. W.) 194

Cartilage, chick, embryonic, incorporation of sulphate intochondroitin sulphate in (Adams, J. B.) 520

Cartilage, human, presence ofsialic acid in (Anderson, A. J.)53P

(+)-Catechin, oxidative condensation of (Evelyn, S. R.,Maihs, E. A. & Roux, D. G.) 23

Cells, mammalian, biosynthesis of ribonucleic acid byparticle-free extracts of (Burdon, R. H. & Smellie,R. M. S.) 2P

Cerebral cortex, isolated, migration of histones from nucleiof, kept in cold media (Wolfe, L. S. & McIlwain, H.)65P

Cerebral cortex, maminalian, ionic movements with elec-trical pulses in (Cummins, J. T. & Mcllwain, H.) 64P

Cerebral tissues, isolated, characterization of constituentsof blood plasma and brain which restore excitability to(Mcllwain, H.) 16P

Chelating agents, effects of, on roots of tomato seedlings(Cocking, E. C.) 51P

Chlorella, photosynthetic triphosphopyridine nucleotidereductase from (Hill, R. & Bendall, F.) 47P

Chlorpromazine, action of, on mitochondrial adenosine tri-phosphatase and the adenosine triphosphate-adenosinediphosphate exchange (Dawkins, M. J. R., Judah, J. D.& Rees, K. R.) 200

Cholesterol esterase, pancreatic, manometric assay and pro-perties of (Korzenovsky, M., Diller, E. R., Marshall, A. C.& Auda, B. M.) 238

Cholinesterase, serum, activity of, in health and in liverdisease (Kekwick, R. G. 0.) 420

Chondroitin sulphate, incorporation of sulphate into, inembryonic chick cartilage (Adams, J. B.) 520

Cinnamic acids, metabolism of, in higher plants (Harborne,J. B. & Corner, J. J.) 53P

Citrate excretion and renal-tissue citrate in rat (Crawford,M. A. & Milne, M. D.) 23P

632 1960

INDEX OF SUBJECTSCitrate, inhibition of amylase activity ofhuman body fluidsby (Street, H. V.) 10

Citric acid-cycle intermediates, effect of, on oxaloacetateutilization and succinate oxidation (Tyler, D. B.)293

Cobalamin and the synthesis of methionine by ultrasonicextracts of Escherichia coli (Guest, J. R., Helleiner, C. W.,Cross, M. J. & Woods, D. D.) 396

Cobalamin, inhibition ofmethionine synthesis in Escherichiacoli by analogues of (Guest, J. R.) 405

Cobalt, effect of, on metabolism of rat dermal fibroblasts inculture (Daniel, M., Dingle, J. T. & Webb, M.) 24P

Collagen, action of y-rays on (Bowes, J. H., Moss, J. A. &Raistrick, A. S.) 21P

Collagen, experiments on metabolism of, in lathyrism(Kulonen, E., Salmi, A. & Juva, K.) 54P

Collagen, interaction of, with hyaluronic acid (Fessler,J. H.) 124

Collagen, neutral-salt-soluble, properties of (Fessler, J. H.)463

Connective tissue, structural function of mucopolysac.charide in (Fessler, J. H.) 124

Coproporphyrin III, isolation of, from Mycobacterium tuber-cutosis avium (Patterson, D. S. P.) 189

Corticosterone, recovery of, from lipids produced by ratadrenals in vitro (Ward, P. J. & Birmingham, M. K.)269

Coumarins, metabolism of, in higher plants (Harborne,J. B. & Corner, J. J.) 53P

Creatine, concentration of, in synovial tissue (Cook, E. R.,Thomas, D. P. Page & Dingle, J. T.) 120

Creatine phosphokinase, thiol group in the 'active site' of(Watts, D. C., Rabin, B. R. & Crook, E. M.) 7P

Cystamine (2:2'-diaminodiethyl disulphide), reaction of,with sulphite at low pH (Cecil, R.) 156

Cystinylvaline, synthesis of optical isomers of (Arnstein,H. R. V. & Morris, D.) 318

L-Cystinyl-L-valine, utilization of, for penicillin biosynthesis(Arnstein, H. R. V. & Morris, D.) 323

Cytidine diphosphate choline content of brain tissue(Ansell, G. B. & Bayliss, B. J.) 20P

Cytochrome oxidase, some kinetic observations on a newpreparation of (Gibson, Q. H., Greenwood, C. & Massey,V.) 46P

Cytochrome b in non-phosphorylating heart-muscle par-ticles, oxidation-reduction potential of (Holton, F. A. &Colpa-Boonstra, J.) 179

DDT, effect of, on phosphorus metabolism of adult house-fly (Winteringham, F. P. W., Hellyer, G. C. & McKay,M. A.) 543

1l-Dehydrocorticosterone, recovery of, from lipids pro-duced by rat adrenals in vitro (Ward, P. J. & Birming-ham, M. K.) 269

l1-Deoxycorticosterone, recovery of, from lipids producedby rat adrenals in vitro (Ward, P. J. & Birmingham,M. K.) 269

Deoxyribonucleases as growth substances (Zahn, R. K.)66P

Deoxyribonucleic acid, factors controlling enzymic synthesis of (Weissman, S. M., Gray, E. D., Thomson, R. Y.,Smellie, R. M. S. & Davidson, J. N.) 26P

Dextran, basic derivative of, and its interaction withserum albumin (McKernan, W. M. & Ricketts, C. R.)117

2:2'-Diaminodiethyl disulphide (cystamine), reaction of,with sulphite at low pH (Cecil, R.) 156

Diaminopimelic acid, effects of penicillin on a mutant ofEscherichia coli requiring (Meadow, P.) 8P

Diaphragm, rat, insulin-stimulated incorporation of[14C]glucose into two glucose complexes of (Walaas, O.,Walaas, E., Borrebaek, B. & Kristiansen, T.) 68P

Diauxic effect, nature of, with glucose and organic acids inPseudomonas aeruginosa (Hamilton, W. A. & Dawes,E. A.) 70P

Dieldrin, effect of, on phosphorus metabolism of adulthousefly (Winteringham, F. P. W., Hellyer, G. C. &McKay, M. A.) 543

Diethylaminoethyl ethers of dextrans (McKernan, W. M.& Ricketts, C. R.) 117

Diethylaminoethylcellulose, separation of urine colloids on(Anderson, A. J., Lepper, M. H. & Winzler, R. J.) IOP

4:5-Dihydroxyphthalic acid decarboxylase, activity of, inextracts of Pseudomonas sp. (Ribbons, D. W. & Evans,W. C.) 310

Dimethylnitrosamine, inhibition by, of incorporation oflabelled amino acids into proteins of rat-liver prepara-tions in vitro (Hultin, T., Arrhenius, E., Low, H. &Magee, P. N.) 109

Dimethylnitrosamine, probable alkylation of liver ribo-nucleic acid by (Farber, E. & Magee, P. N.) 58P

2:4-Dinitrophenol, effect of, on glucose metabolism inbaker's yeast (Moses, V. & Smith, M. J. H) 585

2:4-Dinitrophenol, effect of, on incorporation of 14C from[14C]glucose and [14C]acetate into soluble intermediatesof rat tissues (Smith, M. J. H. & Moses, V.) 579

2:4-Dinitrophenol, effect of, on the metabolism of [3-14C]-pyruvate in isolated rat tissues (Huggins, A. K., Moses, V.& Smith, M. J. H.) 1rP

e-Dinitrophenyl-lysine, reduction of aromatic nitro groupsduring acid hydrolysis in the presence of carbohydratesand its bearing on the colorimetric determination of(Handwerck, V., Bujard, E. & Mauron, J.) 54P

Diphosphoinositide fractions, ox-brain, hydrolysis of (Ellis,R. B., Kemp, P. & Hawthorne, J. N.) 43P

Diphosphopyridine nucleotide, reduced, effects of carbondioxide on tho oxidation of, by Ricinu8 mitochondria(Bendall, D. S., Ranson, S. L. & Walker, D. A.) 221

Disulphide groups of insulin, reaction of, with sodiumsulphite (Cecil, R. & Loening, U. E.) 146

Ear cartilage, rabbit, chemical changes in, induced bypapain and calciferol (Grant, R. A., Hathorn, M. & Gill-man, T.) 412

Earthworm (Megascolides cameroni), formation in vivo oflombricine in (Rossiter, R. J., Gaffney, T. J., Rosenberg,H. & Ennor, A. H.) 603

ECTEOLA-cellulose, fractionation of nucleoproteins on(Creaser, E. H. & Spencer, J. H.) 171

Ehrlich ascites tumour cells, pyridine nucleotide content ofmitochondria of (Borst, P. & Colpa-Boonstra, J. P.) 60P

Encephalomyocarditis-virus infection, effect of, on theribonucleic acid metabolism of Krebs II mouse ascitescells (Martin, E. M.) 30P

A-Endolysin, digestion of cell walls of Escherichia coli andBacillus megaterium by (Work, E. & Lecadet, M.) 39P

A-Endolysin, properties of (Work, E.) 38PEntodinium, carbohydrate metabolism of (Abou Akkada,

A. R. & Howard, B. H.) 445Enzyme synthesis and nucleic acid turnover in resting

bacteria (Proctor, M. H.) 57PEnzymes associated with disintegrated cells and extracts of

spirochaetes (Smith, P. J. C.) 500Ervthrocytes, human, effect of human-serum albumin on

oxidation of glutathione in (Jocelyn, P. C.) 6PEscherichia coli, cobalamin and the synthesis of methionineby ultrasonic extracts of (Guest, J. R., Helleiner, C. W.,Cross, M. J. & Woods, D. D.) 396

Escherichia coli, digestion of cell walls of, by A-endolysin orlysozyme (Work, E. & Lecadet, M.) 39P

Escherichia coli, effects of penicillin on a mutant of, re-quiring diaminopimelic acid (Meadow, P.) 8P

Escherichia coli, inhibition of methionine synthesis in, byanalogues of cobalamin (Guest, J. R.) 405

Vol. 76 633

INDEX OF SUBJECTSE8cherichia coli (A), lysogenic, properties of A-endolysin, the

lytic enzyme in lysates of (Work, E.) 38PEthionine, probable alkylation of liver ribonucleic acid by

(Farber, E. & Magee, P. N.) 58P

Fat intake, dietary, effect of, on polyunsaturated fattyacids in human-blood serum (Patil, V. S. & Magar,N. G.) 417

Fatty acid svnthesis in vitro, stimulation of, by oestradiol(Hosoya, N., Hagerman, D. & Villee, C.) 297

Fatty acids of human-plasma phospholipids (Rowe, C. E.)471

Fatty acids, oxidation of, by a particulate fraction fromdesert-locust (Schistocerca gregaria) thorax tissues (Meyer,H., Preiss, B. & Bauer, Sh.) 27

Fatty acids, polyunsaturated, effect of dietary fat intakeand age on, in human-blood serum (Patil, V. S. & Magar,N. G.) 417

Fatty acids, volatile, production of, by Entodinium (AbouAkkada, A. R. & Howard, B. H.) 445

Fibroblasts, dermal, rat, effect of cobalt on metabolism of,in culture (Daniel, M., Dingle, J. T. & Webb, M.)24P

Flavoprotein, selective inhibition by 2-heptyl-4-hydroxy-quinoline N-oxide of some peroxidative reactions cata-lysed by (Kogut, M. & Lightbown, J. W.) 8P

Fluorine compounds in African plants (Peters, R. A.) 32PFluoropyruvate, effect of particle-bound y-glutamyltrans-

peptidase on the product of interaction of, with gluta-thione (Avi-Dor, Y.) 370

Formalin, extraction of lipid matter by (Chayen, J., Chayen,R. & Aves, E. K.) 14P

French-bean (Phaseolu8 vulgari8) seedlings, effect of illumi-nation on carotenoid synthesis in (Goodwin, T. W. &Phagpolngarm, S.) 197

[14C]Fructose, metabolism of, after limb ischaemia in rat(Stoner, H. B., Heath, D. F. & Collins, 0. M.) 135

L-Galactono-y-lactone, conversion of, into L-ascorbic acid(Isherwood, F. A., Mapson, L. W. & Chen, Y. T.) 157

D-Galactose, enzymic polymerization of (Clancy, M. J. &Whelan, W. J.) 22P

Gases, kinetics of the reactions of natural and reconstitutedhaemoglobins with (Antonini, E. & Gibson, Q. H.) 534

Gastric enzymes (Ryle, A. P.) 34PGastrointestinal proteinases, mechanism of action of

(Taylor, W. H.) 36Py-Globulin, human, metabolic heterogeneity of (Cohen, S.& Freeman, T.) 475

y-Globulin, rabbit, specificity of antigens of, hydrolysed bypapain (Kelus, A., Marrack, J. R. & Richards, C. B.)13P

y-Globulins, rabbit, serological classification of (Kelus, A.)13P

4-0-(,-D-Glucopyranosyl)-D-ribitol from hydrolysis of ribi-tol teichoic acid (Armstrong, J. J., Baddiley, J. &Buchanan, J. G.) 610

Glucose breakdown in chick-embryo cells infected withinfluenza virus (Klemperer, H. G.) 67P

Glucose metabolism, effects of 2:4-dinitrophenol and sali-cylate on, in baker's yeast (Moses, V. & Smith, M. J. H.)585

Glucose metabolism, restriction of the availability of par-ticle-bound nucleotides as a controlling mechanism of(Bala'zs, R. & Richter, D.) 67P

Glucose, nature of the diauxic effect with, in Pseudomonasaeruginosa (Hamilton, W. A. & Dawes, E. A.) 70P

Glucose, non-enzymic interaction of phosphate and, inaqueous solutions (Lewin, S.) 17P

[14C]Glucose, effect of salicylate and 2:4-dinitrophenol onincorporation of 14C from, into soluble intermediates ofrat tissues (Smith, M. J. H. & Moses, V.) 579

[14C]Glucose, insulin-stimulated incorporation of, into twoglucose complexes of rat diaphragm (Walaas, O.,Walaas, E., Borrebaek, B. & Kristiansen, T.) 68P

[14C]Glucose, metabolism of, after limb ischaemia in rat(Stoner, H. B., Heath, D. F. & Collins, 0. M.) 135

D-Glucuronolactone, conversion of, into L-ascorbic acid(Chatterjee, I. B., Chatterjee, G. C., Ghosh, N. C., Ghosh,J. J. & Guiha, B. C.) 279

Glucuronosides, steroid, urinary, isolation of (Foggitt, F.& Kellie, A. E.) 62P

Glutamylcystinylvaline, synthesis of the a- and y-isomersof (Morris, D.) 349

y-Glutamyltranspeptidase, particle-bound, effect of, on theproduct of interaction of fluoropyruvate with gluta-thione (Avi-Dor, Y.) 370

Glutathione, effect of particle-bound y-glutamyltranspep-tidase on the product ofinteraction offluoropyruvate with(Avi-Dor, Y.) 370

Glutathione in human erythrocytes, effect of human-serumalbumin on oxidation of (Jocelyn, P. C.) 6P

Glutathione, some effects of, on protamine-treated aminoacid-activating systems (Hele, P.) 59P

L-z-Glycerophosphate-dehydrogenase component ofoxidasesystem in Trypano8ma rhodesienwe (Grant, P. T. &Sargent, J. R.) 48P

L-a-Glycerophosphate oxidase, properties of, and its role inthe respiration of TrypanO8oma rhodesien8e (Grant, P. T.& Sargeant, J. R.) 229

Glycogen, action of human salivary a-amylase on (Roberts,P. J. P. & Whelan, W. J.) 246

Glycogen, stages in the salivary z-amylolysis of (Walker,G. J. & Whelan, W. J.) 257

Glycogen, structures of muscle-phosphorylase limit dex-trins of (Walker, G. J. & Whelan, W. J.) 264

Glycogen-storage disease, amylo-1:6-glucosidase activityin tissues of children with (Hers, H. G.) 69P

Glycolysis in rat brain after shock with and without tran-quillization (Ninomiya, H., Buxton, R. W. & Michaelis,M.) 47P

Glycosidases in aspen tissues (Pridham, J. B.) 13Growth, promotion of, by a non-diabetogenic derivative of

alloxan (Manchester, K. L. & Young, F. G.) 68PGuanidine, effect of, on mitochondrial adenosine triphos-

phatase (Dawkins, M. J. R., Judah, J. D. & Rees, K. R.)200

L-Gulonolactone, conversion of, into L-ascorbic acid (Chat-terjee, I. B., Chatterjee, G. C., Ghosh, N. C., Ghosh, J. J.& Guha, B. C.) 279

L-Gulono-y-lactone, conversion of the free acid and, intoL-ascorbic acid (Isherwood, F. A., Mapson, L. W. & Chen,Y. T.) 157

Haemoglobins, hybrid, starch-gel electrophoresis appliedto the detection of (Gammack, D. B., Huehns, E. R.,Lehmann, H. & Shooter, E. M.) 55P

Haemoglobins, natural and reconstituted, kinetics of thereactions with gases of (Antonini, E. & Gibson, Q. H.)534

Haemoproteins, selective inhibition by 2-heptyl-4-hydroxy-quinoline N-oxide of some peroxidative reactions cata-lysed by (Kogut, M. & Lightbown, J. W.) 8P

Heart, metabolism of urea by (Menne, F.) 63PHeart-muscle particles, non-phosphorylating, oxidation-

reduction potential of cytochrome b in (Holton, F. A. &Colpa-Boonstra, J.) 179

Heart-muscle preparations, kinetics of ubiquinone reactionsin (Redfearn, E. R. & Pumphrey, A. M.) 64

Hens, aromatization of cyclohexanecarboxylic acid in(Baldwin, B. C., Robinson, D. & Williams, R. T.)600

Hepatoma, Novikoff, comparison of nucleic acids of ratliver and (Creaser, E. H. & Spencer, J. H.) 171

634 1960

INDEX OF SUBJECTS2-Heptyl-4-hydroxyquinoline N-oxide, selective irhibition

by, of some peroxidative reactions catalysed by haemo-proteins and by a flavoprotein (Kogut, M. & Lightbown,J. W.) 8P

cycloHexanecarboxylic acid, aromatization of, in hens(Baldwin, B. C., Robinson, D. & Williams, R. T.)600

Hexokinase, properties of, in spirochaetes (Smith, P. J. C.)514

Hexosamine, content of, in cartilage and aorta in rabbit(Grant, R. A., Hathorn, M. & Gillman, T. 412

Hexose metabolism in maize roots (Butt, V. S. & Beevers,H.) 51 P

Hippuric acid, excretion of, by birds after feeding withbenznic acid (Baldwin, B. C., Robinson, D. & Williams,R. T.) 595

Histones, migration of, from nuclei of isolated cerebraltissues kept in cold media (Wolfe, L. S. & Mcllwain, H.)65P

Housefly (Mu8ca domestica L.), adult, effects of DDT anddieldrin on phosphorus metabolism of (Winteringham,F. P. W., Hellyer, G. C. & McKay, M. A.) 543

Hyaluronic acid, interaction of, with collagen (Fessler,J. H.) 124

Hyaluronidase, testicular, mode of action of (Fessler, J. H.)132

Hydrazines, effect of, on monoamine oxidase and somepyridoxal phosphate-requiring enzymes (Heilbronn, E.)45P

D-x-Hydroxy acid dehydrogenase, mitochondrial, someproperties of (Tubbs, P. K.) 48P

16-Hydroxy steroid dehydrogenase, demonstration of, inrat kidney (King, R. J. B.) 7P

,B-Hydroxybutyric acid, formation of, by human placenta(Hosoya, N., Hagerman, D. & Villee, C.) 297

Hydroxyindole oxidases, observations on (Levine, W. G.)43P

3a-Hydroxy-5,-pregnan-20-one, presence of, in urine (Con-tractor, S. F. & Pearlman, W. H.) 36

,5-Hydroxytryptamine in cytoplasmic particles of smallintestine (Prusoff, W. H.) 65P

5-Hydroxytryptamine, some aspects of metabolism of(Chadwick, B. T. & Wilkinson, J. H.) 102

Indolyl-3-carboxylic acid, urinary conjugate of (Bala-krishnan, S. & Rodnight, R.) 61P

Influenza virus, glucose breakdown in chick-embryo cellsinfected with (Klemperer, H. G.) 67P

Inorganic ions, effect of oxygen concentration on nitriteoxidation by Nitrobacter in the presence of (Butt, W. D.& Lees, H.) 425

Inositol phosphatide, brain, studies of biosynthesis of(Strickland, K. P., Thompson, W., Subrahmanyam, D.& Rossiter, R. J.) 41P

Insecticides, effect of, on phosphorus metabolism of adulthousefly (Winteringham, F. P. W., Heilyer, G. C. &McKay, M. A.) 543

Insulin, determination of the insulin-like activity of theA-chain of (Fisher, R. B. & Zachariah, P.) 155

Insulin, incorporation of [14C]glucose into two glucose com-plexes of rat diaphragm stimulated by (Walaas, 0.,Walaas, E., Borrebaek, B. & Kristiansen, T.) 68P

Insulin, reaction of disulphide groups of, with sodium sul-phite (Cecil, R. & Loening, U. E.) 146

Interferon, purification of (Burke, D. C.) 50PIntestine, small, adenosine triphosphate and 5-hydroxy-tryptamine in cytoplasmic particles of (Prusoff, W. H.)65P

Intestine, small, rat, transport ofiodide by, in vitro (Acland,J. D. & Johnson, S.) 19P

Intrinsic factor, some experiments on (Heatley, N. G.,Sheikh, M. A. & Taylor, K. B.) 342

Iodide, transport of, by small intestine of rat in vitro(Acland, J. D. & Johnson, S.) 19P

Iodine isotopes (131I and 1251), labelling of plasma proteinwith (Cohen, S. & Freeman, T.) 475

Ionic movements with electrical pulses in mammalian cere-bral cortical tissue (Cummins, J. T. & McIlwain, H.)64P

Iris leaves, stability of ascorbic acid in extracts of (Booth,V. H. & Constable, B. J.) 206

Ischaemia, limb, metabolism of [14C]glucose, [14C]fructoseand [2-14C]pyruvate after, in rat (Stoner, H. B., Heath,D. F. & Collins, 0. M.) 135

Ketone-body formation, mechanism of (Hird, F. J. R. &Symons, R. H.) 25P

Kidney, chicken, synthesis of L-ascorbic acid in prepara-tions from (Chatterjee, I. B., Chatterjee, G. C., Ghosh,N. C., Ghosh, J. J. & Guha, B. C.) 279

Kidney, rat, demonstration of a 16-hydroxy steroid dehy-drogenase in (King, R. J. B.) 7P

Krebs cycle in mitochondria of Ricinus, effect of carbondioxide on (Ranson, S. L., Walker, D. A. & Clarke, I. D.)216

Lactic dehydrogenase, ox-brain, fluorescent studies of(Winer, A. D.) 5P

Lactic dehydrogenase, ox-brain, purification and somekinetic properties of (Winer, A. D.) 5P

Lactic dehydrogenase, properties of, in spirochaetes (Smith,P. J. C.) 514

Lactonase, partial purification of, from rat liver (Isherwood,F. A., Mapson, L. W. & Chen, Y. T.) 157

Lamellibranch crystalline style (Bailey, K. & Worboys,B. D.) 487

Lathyrism, experiments on metabolism of collagen in(Kulonen, E., Salmi, A. & Juva, K.) 54P

Lens peptidase, enzymology and comparative biochemistryof (Zeller, E. A., Banerjee, R. & Shoch, D.) 49P

Leucocytes, human, circulating, oxygen consumption of,after intravenous injection of tri-iodothyroacetic acidand tri-iodothyronine (Bisset, S. K., Alexander, W. D. &Crooks, J.) 20P

Light, effect of, on carotenoids of etiolated French-beanseedlings (Goodwin, T. W. & Phagpolngarm, S.) 197

Lipid matter, extraction of, by formalin (Chayen, J.,Chaven, R. & Aves, E. K.) 14P

Lipids, ultraviolet-absorbing, properties of, produced byrat adrenals in vitro (Ward, P. J. & Birmingham, M. K.)269

Liver disease, serum-cholinesterase activity in (Kelwick,R. G. 0.) 420

Liver, human and rat, androgens as activators of pyridinenucleotide transhydrogenase in (Williams, D. C., Baron,D. N. & Gore, M. B. R.) 37P

Liver, metabolic activities of a peptidylphosphatide of(Tria, E. & Barnabei, 0.) 36P

Liver mitochondria, rat, isolated, exchange of potassiumions across a concentration difference by (Amoore, J. E.)438

Liver, mouse, effect of Plamodium berghei malaria on mito-chondria of (Riley, M. V. & Deegan, T.) 41

Liver, rat, comparison of the nucleic acids of Novikoffhepatoma and (Creaser, E. H. & Spencer, J. H.) 171

Liver, rat, inhibition by dimethylnitrosamine of incorpora-tion of labelled amino acids into proteins of preparationsof, in vitro (Hultin, T., Arrhenius, E., Low, H. & Magee,P. N.) 109

Liver, rat, presence of basic proteins in ribonucleoproteinsof (Cohn, P., Simson, P. & Butler, J. A. V.) 23P

Liver ribonucleic acid, probable alkylation of, by dimethyl-nitrosamine and ethionine (Farber, E. & Magee, P. N.)58P

Vol. 76 635

INDEX OF SUBJECTSLiver ribosomes, rat, isolated, incorporation of radioactiveamino acids into serum albumin by (Korner, A.) 59P

Liver, synthesis of L-ascorbic acid in preparations from(Chatterjee, I. B., Chatterjee, G. C., Ghosh, N. C., Ghosh,J. J. & Guha, B. C.) 279

Locust (Schistocerca gregaria), carbohydrases in alimentarytract of (Evans, W. A. L. & Payne, D. W.) 50P

Locust (Schistocerca gregaria), desert, oxidation of fattyacids by a particulate fraction from thorax tissues of(Meyer, H., Preiss, B. & Bauer, Sh.) 27

Lombricine, formation in vivo of, in earthworm (Rossiter,R. J., Gaffney, T. J., Rosenberg, H. & Ennor, A. H.)603

Lycopene, incorporation of [1-14C]acetate, [2-14C]acetateand "4CO2 into, by tomato slices (Braithwaite, G. D. &Goodwin, T. W.) 1

DL-[2-14C]Lysine, metabolism of, in turkey poults (Vohra,P. & Kratzer, F. H.) 37P

Lysozyme, digestion of cell walls of Escherichia coli andBacillus megaterium by (Work, E. & Lecadet, M.) 39P

Magnesium and calcium absorption, inter-relation of(Alcock,N. & Maclntyre, I.) 19 P

Maize roots, hexose metabolism in (Butt, V. S. & Beevers,H.) 51 P

Malaria, Plasmodium berghei, effect of, on mouse-livermitochondria (Riley, M. V. & Deegan, T.) 41

Malic dehydrogenase, ox-brain, fluorescent studies of(Winer, A. D.) 5P

Malic dehydrogenase, ox-brain, purification and somekinetic properties of (Winer, A. D.) 5P

Malic dehydrogenases, comparison of (Thorne, C. J. R.) 4PMegascolides cameroni see EarthwormMeromyosins, bovine, reactions of, with antiserum to

bovine myosin (Furminger, I. G. S.) 12PMetal complexes, a potentiometric method for determina-

tion of stability constants of, and its application to com-plexes of adenine anion (Albert, A. & Serjeant, E. P.)621

Metal linkages in the thymus nucleohistone and theirdamage by X-irradiation (Hagen, U.) 56P

Metal-peptide complexes and proteolytic enzymes (Rabin,B. R.) 33P

Methanol incorporation by Pseudomonas sp. AM 1 (Quayle,J. R. & Peel, D.) 3P

Methionine, cobalamin and the synthesis of, by ultrasonicextracts of Eseherichia coli (Guest, J. R., Helleiner, C. W.,Cross, M. J. & Woods, D. D.) 396

Methionine synthesis in Escherichia coli, inhibition of, byanalogues of cobalamin (Guest, J. R.) 405

5-[P-14C]Methoxytryptamine, metabolism of (McIsaac,W. M., Kveder, S. & Page, I. H.) 30P

Methylene blue, mechanism of reduction of, in glucose-glycine-phosphate solutions (Lewin, S.) 17P

[14C]Mevalonate, incorporation of, into P-carotene bv thefungus Phycomyces blakesleeanus (Braithwaite, G. D. &Goodwin, T. W.) 5

DL-[2-14C]Mevalonate, incorporation of, into carrot-rootpreparations (Braithwaite, G. D. & Goodwin, T. W.)194

Mitochondria, behaviour of pyridine nucleotidc o', in a'saline medium' (Birt, L. M. & Bartley, W.) 328

Mitoch-ndria, effect of incubation conditions on respirationof (Bellamy, D. & Bartley, W.) 78

Mitochondria, effects of carbon dioxide on enzymes of,from Ricinus (Ranson, S. L., Walker, D. A. & Clarke,I. D.) 216

Mitochondria, method for determining the concentration ofubiquinone in preparations of (Pumphrey, A. M. & Red-fearn, E. R.) 61

Mitochondria, mouse-liver, effect of Plasmodium bergheimalaria on (Riley, M. V. & Deegan, T.) 41

Mitochondria of Ehrlich ascites tumour cells, pyridinenucleotide content of (Borst, P. & Colpa-Boonstra, J. P.)60P

Mitochondria, pyridine nucleotide metabolism of, incubatedwith and without added substrates and metabolic in-hibitors (Birt, L. M. & Bartley, W.) 427

Mitochondria, rat-liver, isolated, exchange of potassium ionsacross a concentration difference by (Amoore, J. E.) 438

Mitochondria, Ricinus, effects of carbon dioxide on theoxidation of succinate and reduced diphosphopyridinenucleotide by (Bendall, D. S., Ranson, S. L. & Walker,D. A.) 221

Monoamine oxidase, effect of hydrazines and amines on(Heilbronn, E.) 45P

Monoamine oxidase, estimation of (Green, A. L. & Haugh-ton, T. M.) 44P

Monoamine oxidases, further exploration of the activecentre of (Zeller, E. A., Pacha, W. L. & Sarkar, S.) 45P

Monomalonyl-coenzyme A, formation of, by human pla-centa (Hosoya, N., Hagerman, D. & Villee, C.) 297

Mucopolysaccharide, structural function of, in connectivetissue (Fessler, J. H.) 124

Muramic acid, possible precursors for synthesis of, byStaphylococcus aureus 524 (Richmond, M. H. & Perkins,H. R.) 1 P

Musca domestica L. see Housefly, adultMuscle-phosphorylase limit dextrins of glycogen and amylo-

pectin, structures of (Walker, G. J. & Whelan, W. J.)264

Mycobacterium smegmatis, oxidation of natural polyaminesby (Bachrach, U., Persky, S. & Razin, S.) 306

Mycobacterium tuberculosis avium, isolation of copropor-phyrin III from (Patterson, D. S. P.) 189

Myometrium, rat, cytoplasmic fractions of (Wakid, N. W.)88

Myometrium, rat, localization of some cellular constituentsin, in pregnant and ovariectomized states (Wakid, N. W.& Needham, D. M.) 95

Myosin, bovine, reactions of bovine meromyosins with anti-serum to (Furminger, I. G. S.) 12P

L-Myosin, effects of phenylmercuric acetate on enzymicactivity of (Greville, G. D. & Tapley, D. F.) 49P

Naphthyl phosphates, kinetics of phosphatase action on,determined by a highly sensitive spectrofluorimetrictechnique (Moss, D. W.) 32P

Neutral-salt-soluble collagen, some properties of (Fessler,J. H.) 452, 463

Niacin, presence of, in yellow pigment of bull semen(White, I. G. & Lincoln, G. J.) 301

Niacytin, isolation of (Kodicek, E. & Wilson, P. W.) 27PNitrite, effect of oxygen concentration on oxidation of, by

Nitrobacter in the presence of different inorganic ions(Butt, W. D. & Lees, H.) 425

Nitro groups, aromatic, reduction of, during acid hydrolysisin the presence of carbohydrates and its bearing on thecolorimetric determination of E-dinitrophenyl-lysine(Handwerck, V., Bujard, E. & Mauron, J.) 54P

Nitrobacter, effect of oxygen concentration on nitrite oxid-ation by, in the presence of different inorganic ions (Butt,W. D. & Lees, H.) 425a

Novikoff hepatoma, comparison of nucleic acids of rat liverand (Creaser, E. H. & Spencer, J. H.) 171

Nucleic acid turnover and enzyme synthesis in resting bac-teria (Proctor, M. H.) 57P

Nucleic acids of rat liver and Novikoff hepatoma, compari-son of (Creaser, E. H. & Spencer, J. H.) 171

Nucleotides, particle-bound, restriction of the availabilityof, as a controlling mechanism of glucose metabolism(Balazs, R. & Richter, D.) 67P

Nucleotides, soluble, of baker's yeast (Miettinen, J. K. &Savioja, T.) 66P

636 1960

INDEX OF SUBJECTSObese mice, metabolism in New Zealand strain of (Subrah-manyam, K.) 548

Oestradiol, stimulation of fatty acid synthesis by, in vitro(Hosoya, N., Hagerman, D. & Villee, C.) 297

Oestradiol-17,B, effect of, on the production of reduced tri-phosphopyridine nucleotide in rat uterus (Mongkolkul,K. & Grant, J. K.) 46P

Oligosaccharides in aspen tissues (Pridham, J. B.) 13Oophorectomi7zed-hysterectomized women, metabolism of

[16-311]progesterone in (Contractor, S. F. & Pearlman,W. H.) 36

L( + )-Ornithuric acid, exeretion of, by birds after feedingwith benzoic acid (Baldwin, B. C., Robinson, D. & Wil-liams, R. T.) 595

L( + )-Ornithuric acid, excretion of, by the hen after feedingwith cyclohexanecarboxylic acid (Baldwin, B. C., Robin-son, D. & Williams. R. T.) 600

Ovariectomy, localization of some cellular constituents inrat myometrium after (Wakid, N. W. & Needham, D. M.)95

Oxalate, metabolism of, in oxalate-grown Pweudomonasoxalaticwq (OX 1) (Quayle, J. R., Keech, D. B. & Taylor,G.A.) 3P

Oxaloacetate utilization, effect of citric acid-cycle inter-mediates on (Tyler, D. B.) 293

Oxidase system, L-a-glycerophosphate dehydrogenase com-ponent of, in Trypano8oma rhodesiense (Grant, P. T. &Sargent, J. R.) 48P

Oxidation-reduction potential of cvtochrome b in non-phosphorylating heart-muscle particles (Holton, F. A. &Colpa-Boonstra, J.) 179

17-Oxo steroid hydrogen sulphates, urinary, extraction andmeasurementof (McKenna,J. & Norymberski, J. K.) 60P

Oxygen consumption of circulating human leucocytes afterintravenous injection of tri-iodothyroacetic acid andtri-iodothyronine (Bisset, S. K., Alexander, W. D. &Crooks, J.) 20P

Oxygen, effect of concentration of, on nitrite oxidation byNitrobacter in the presence of different inorganic ions(Butt, W. D. & Lees, H.) 425

Oxygen, measurement of diffusion of, through respiringtissue (Longmuir, I. S. & Bourke, A.) 225

Papain, chemical changes in rabbit aorta and ear cartilageinduced by (Grant, R. A., Hathorn, M. & Giliman, T.)412

Papain hydrolysates of rabbit y.globulin, specificity of anti-gens of (Kelus, A., Marrtck, J. R. & Richards, C. B.) 13P

Papain, specificity of antigens of rabbit y-globulin hydro-lysed by (Kelus, A., Marrack, J. R. & Richards, C. B.)13P

Pea seedlings, further purification and properties of amineoxidase of (Mann, P. J. G.) 44P

Pea seeds, protein disuliphide reductase from (Hatch,M. D. & Turner, J. F.) 556

Penicillin, effects of, on a mutant of Escherichia coli re-quiring diaminopimelic acid (Meadow, P.) 8P

Penicillin, metabolism of 6-aminopenicillanic acid andrelated compounds by Penicillium chry8oqenum and itspossible significance for biosynthesis of (Wolff, E. C. &Arn.tein, H. R. V.) 375

Penicillin, utilization of L-cystinyl-L-valine for biosynthesisof (Arnstein, H. R. V. & Morris, D.) 323

Penicillium chrysogenum, metabolism of6-aminopenicillanicacid and related compoumds by, and its possible signifi-cance for penicillin biosynthesis (Wolff, E. C. & Arnstein,H. R. V.) 375

Penicillium chrysoqenum, structure of a peptide present inthe mycelium of (Arnstein. H. R. V. & Morris, D.) 357

Penicillium chry8ogenum, sulphur-containing amino acidsand peptides in the mycelium of (Arnstein, H. R. V.,Artman, M., Morris, D. & Toms, E. J.) 353

Penicillium kinase, mechanism of activation of trypsinogenby (Hofmann, T.) 26P

Peptidase, lens, enzymology and comparative biochemistryof (Zeller, E. A., Banerjee, R. & Shoch, D.) 49P

Peptide containing oc-aminoadipic acid, cystine and valine,structure of, present in mycelium of Penicillium chryso-genum (Arnstein, H. R. V. & Morris, D.) 357

Peptides, sulphur-containing, in the mycelium of Penicil-lium chrysogenum (Arnatein, H. R. V., Artman, M.,Morris, D. & Toms, E. J.) 353

Peptidylphosphatide of liver, metabolic activities of (Tria,E. & Barnabei, 0.) 36P

Phaseolus vulgaris (French bean) seedlings, effect of illumi-nation on carotenoid synthesis in (Goodwin, T. W. &Phagpolngarm, S.) 197

Phenylmercuric acetate, effects of, on enzymic activity ofL-myosin (Greville, G. D. & Tapley, D. F.) 49P

Phosphatase action, kinetics of, on naphthyl phosphates,determined by a highly sensitive spectrotiuorimetrictechnique (Moss, D. W.) 32P

Phosphate, non-enzymic interaction of glucose and, inaqueous solutions (Lewin, S.) 17rE

Phosphocreatine, concentration of, in synovial tissue (Cook,E. R., Thomas, D. P. Page & Dingle, J. T.) 120

Phospholipids of human-blood plasma and their exchangewith the cells (Rowe, C. E.) 471

Phosphoprotein, brain, partial purification of, attached tosubcelJular particles (Heald, P. J.) 56P

Phosphorus metabolism, effects of DDT and dieldrin on, ofadult housefly (Winteringham, F. P. W., Hellyer, G. C.& McKay, M. A.) 543

Phosphorylation, oxidative, and barbiturates (Aldridge,W. N. & Parker, V. H.) 47

Phthalic acid, oxidative metabolism of, by soil pseudo-monads (Ribbons, D. W. & Evans, W. C.) 310

Phycomyces blakesleeanus, incorporation of [14C]acetate,[14C]mevalonate and 14C02 into ,-carotene by (Braith-waite, G. D. & Goodwin, T. W.) 5

Placenta, stimulation of fatty acid synthesis in, by oestra-diol (Hosoya, N., Hagerman, D. & Villee, C.) 297

Plant-cell walls, use of tissue cultures for the study of(Lamport, D. T. A. & Northcote, D. H.) 52P

Plasma, blood, characterization of constituents of brainand, which restore excitability to isolated cerebral tissues(Mcllwain, H.) 16P

Plasma proteins, human, y-globulin fraction of (Cohen, S.& Freeman, T.) 475

Plasminogen, activation of, by staphylokinase (Davidson,F. M.) 56

Plkmodium berghei malaria, effect of, on mouse-livermitochondria (Riley, M. V. & Deegan, T.) 41

Pneumococci, pathway of formation of uridine diphos-phogalacturonic acid in (MiUs, G. T., Smith, E. E. B.,Bernheimer, H. P., Austrian, R. & Galloway, B.)31 P

Polyamines. natural, oxidation of, by Mycobacterium 8meg-matis (Bachrach, U., Persky, S. & Razin, S.) 306

Polvsaccharide, type I pneumococcal capsular, purificationand composition of (Smith, E. E. B., Galloway, B. &Mlills, G. T.) 35P

Populus species, oligosaccharides and glycosidases in (Prid-ham, J. B.) 13

Potassium ions, exchange of, across a concentration dif-ference by isolated rat-liver mitochondria (Amoore, J. E.)438

Pregnancy, advanced, metabolism of [16-8H]progesteronein (Contractor, S. F. & Pearlman W. H.) 36

Pregnancy, localization of some cellular constitiuents in ratmvometrium during (Wakid, N. W. & Needham, D. M.)95

5fi-Pregnane-3:20-dione, presence of, in urine (Contractor,S. F. & Pearlman, W. H.) 36

Vol. 76 637

INDEX OF SUBJECTS[16-3H]Progesterone metabolism in advanced pregnancyand in oophorectomized-hysterectomized women (Con-tractor. S. F. & Pearlman, W. H.) 36

Protaniine-treated amino acid-activating systems, someeffects of glutathione on (Hele, P.) 59P

Protein content of rat brain after shock with and withouttranquillization (Ninomiya, H., Buxton, R. W. &Michaelis, M.) 47P

Protein disulphide reductase from pea seeds (Hatch, M. D.& Turner, J. F.) 5.56

Protein ofisolated rat-liver ribosomes, amino acid incorpora-tion into (Korner, A.) 28P

Protein, promotion of incorporation of amino acid into, bya non-diabetogenic derivative of alloxan (Manchester,K. L. & Young, F. G.) 68r

Proteins, basic, presence of, in ribonucleoproteins of ratliver (Cohn, P., Simson, P. & Butler, J. A. V.) 23P

Proteins, inhibition by dimethylnitrosamine of incorpora-tion of labelled amino acids into, of rat-liver preparationsin vitro (Hultin, T., Arrhenius, E., Low, H. & Magee,P. N.) I0(9

Proteins, intra- and extra-cellular, interaction of thyroidhormones with (Tata, J. R.) 35P

Proteins, studies on biosynthesis of, in the silkworm (Faulk-ner, P. & Bheemeswar, B.) 71

Proteins, thermodynamic approach to the selective effectof pH in competitive biosynthesis of (Lewin, S.) 29P

Proteins, ultraviolet fluorescence of, in neutral solution(Teale, F. W. J.) 381

Proteolytic enzyme from rabbit spleen, study of (Lapresle,C. & Webb, T.) 538

Protocatechuic acid, bacterial oxidation of (Trippett, S.,Dagley, S. & Stopher, D. A.) 9P

Protocatechuic acid, formation of, by Pseudomonas sp.from phthalic acid and 4:5-dihydroxyphthalic acid(Ribbons, D. W. & Evans, W. C.) 310

Pseudomonads, soil, oxidative metabolism of phthalic acidby (Ribbons, D. W. & Evans, W. C.) 310

Pseudomonws aeruginosa, nature of the diauxic effect withglucose and organic acids in (Hamilton, W. A. & Dawes,E. A.) 70P

P8eudomonas oxakaticu8 (OX 1), oxalate-grown, metabolismof oxalate in (Quayle, J. R., Keech, D. B. & Taylor, G. A.)3P

Pseudomonws sp. AM 1, incorporation of methanol andcarbon dioxide by (Quayle, J. R. & Peel, D.) 3P

Pyridine nucleotide content of mitochondria of Ehrlichascites tumour cells (Borst, P. & Colpa-Boonstra, J. P.)60P

Pyridine nucleotide metabolism of mitochondria incubatedwith and without added substrates and metabolic inhibi-tors (Birt, L. M. & Bartley, W.) 427

Pyridine nucleotide transhydrogenase, androgens as acti-vators of, in human and rat liver (Williams, D. C., Baron,D. N. & Gore, M. B. R.) 37P

Pyridine nucleotides of mitochondria, behaviour of, in a'saline medium' (Birt, L. M. & Bartley, W.) 328

Pyridoxal phosphate-requiring enzymes, effect of hydr.azines and amines on (Heilbronn, E.) 45iP

[2-14C]Pyruvate, metabolism of, after limb ischaemia in rat(Stoner, H. B., Heath, D. F. & Collins, 0. M.) 135

[3-14C]Pyruvate, effects of salicylate and 2:4-dinitrophenolon the metabolism of, in isolated rat tissues (Huggins,A. K., Moses, V. & Smith, M. J. H.) 11P

Pyruvic acid, clastic fission of, in Zymosarcina ventriculi(Arbuthnott, J. P., Bauchop, T. & Dawes, E. A.) 12P

Reductases of rat brain after shock with and without tran-quillization (Ninomiya, H., Buxton, R. W. & Michaelis,M.) 47P

Renal-tissue citrate and citrate excretion in rat (Craw-ford, M. A. & Milne, M. D.) 23P

Respiration ofmitochondria, effect ofincubation conditionson (Bellamy, D. & Bartley, W.) 78

Respiration of Trypanosoma rhodesiense, properties of L-(X-glycerophosphate oxidase and its role in (Grant, P. T. &Sargent, J. R.) 229

Respiration, salt-stimulation of, in carrot slices (Dalgarno,L. & Hird, F. J. R.) 209

Ribitol, failure of bull spermatozoa to oxidize (White, I. G.& Lincoln, G. J.) 301

Ribitol teichoic acid, structure of, from walls of Bacillussubtilis (Armstrong, J. J., Baddiley, J. & Buchanan, J. G.)610

Riboflavin, effect of, on the metabolism of bull spermatozoa(White, I. G. & Lincoln, G. J.) 301

Riboflavin, presence of, in yellow pigment of bull semen(White, I. G. & Lincoln, G. J.) 301

Ribonucleic acid, biosynthesis of, by particle-free extractsof mammalian cells (Burdon, R. H. & Smellie, R. M. S.)2P

Ribonucleic acid, distribution of additional components in,from particulate and soluble fractions of cells (Dunn.D. B., Smith, J. D. & Simpson, M. V.) 24P

Ribonucleic acid, liver, probable alkylation of, by dimethyl-nitrosamine and ethionine (Farber, E. & Magee, P. N.)58P

Ribonucleic acid, low-angle X-ray-scattering studies of, insolution (Timasheff, S. N. & Luzzati, V.) 57P

Ribonucleic acid metabolism, effect of encephalomyo-carditis-virus infection on, of Krebs II mouse ascites cells(Martin, E. M.) 30P

Ribonucleic acid synthesis in extracts of mammalian cells(Burdon, R. H. & Smellie, R. M. S.) 21P

Ribonucleoproteins of rat liver, presence of basic proteinsin (Cohn, P., Simson, P. & Butler, J. A. V.) 23P

Ribosomes, rat-liver, isolated, amino acid incorporationinto protein of (Korner, A.) 28P

Ribosomes, rat-liver, isolated, incorporation of radioactiveamino acids into serum albumin by (Korner, A.)59P

Ricinus, effects of carbon dioxide on mitochondrial en-zymes from (Ranson, S. L., Walker, D. A. & Clarke, I. D.)216

Salicylate, effect of, on glucose metabolism in baker's yeast(Moses, V. & Smith, M. J. H.) 585

Salicylate, effect of, on incorporation of 14C from [14C]glu-cose and [14C]acetate into soluble intermediates of rattissues (Smith, M. J. H. & Moses, V.) 579

Salicylate, effect of, on the metabolism of [3-1'C]pyruvatein isolated rat tissues (Huggins, A. K., Moses, V. &Smith. M. J. H.) 11P

Saliva, inhibition of amylase activity of, by citrate (Street,H. V.) 10

Salivary a-amylase, human, action of, on amylopectin andglycogen (Roberts, P. J. P. & Whelan, W. J.) 246

Salivary a-amylase limit dextrin from amylopectin, struc-ture of (Bines, B. J. & Whelan, W. J.) 253

Salivary a-amylolysis of amylose, amylopectin and glyco-gen, stages in (Walker, G. J. & Whelan, W. J.) 257

Schinopsis spp., distribution and deposition of tannins inheartwood of (Roux, D. G. & Evelyn, S. R.) 17

Schistocerca gregaria (desert locust), oxidation of fatty acidsby a particulate fraction from thorax tissues of (Meyer,H., Preiss, B. & Bauer, Sh.) 27

Semen, bull, content of riboflavin, niacin, thiamine andrelated compounds in yellow pigment of (White, I. G. &Lincoln, G. J.) 301

Serum-cholinesterase activity in health and in liver disease(Kekwick, R. G. 0.) 420

Shock, reductases, glycolysis and protein content of ratbrain after, with and without tranquillization (Ninomiya,H., Buxton, R. W. & Michaelis, M.) 47P

638 1960

INDEX OF SUBJECTSSialic acid, presence of, in human cartilage (Anderson, A. J.)53P

Silkworm, Bombyx mori (L.), studies on biosynthesis ofproteins in (Faulkner, P. & Bheemeswar, B.) 71

Sodium sulphite, reaction of disulphide groups of insulinwith (Cecil, R. & Loening, U. E.) 146

Spirochaetes, carbohydrate metabolism of, in vivo and invitro (Fulton, J. D. & Smith, P. J. C.) 491

Spirochaetes, enzymes associated with disintegrated cellsand extracts of (Smith, P. J. C.) 500

Spirochaetes, properties of aldolase in (Smith, P. J. C.)508

Spirochaetes, properties of hexokinase and lactic dehydro-genase in (Smith, P. J. C.) 514

Spleen, rabbit, study of a proteolytic enzyme from (La-presle, C. & Webb, T.) 538

Staphylococcus aureus 524, possible precursors for synthesisof muramic acid by (Richmond, M. H. & Perkins, H. R.)1P

Staphylokinase, activation of plasminogen by (Davidson,F. M.) 56

Starch-gel electrophoresis applied to the detection of hybridhaemoglobins (Gammack, D. B., Huehns, E. R., Leh-mann, H. & Shooter, E. M.) 55P

Steroid sulphates, urinary, direct chromatographic estima-tion of (Bush, I. E. & Gale, M. M.) 10P

Streptokinase, activation of plasminogen by (Davidson,F. M.) 56

Streptomycin, action of, on Vibrio cholerae (Krishna Murti,C. R.) 362

Streptomycin, decrease in oxidative activities of bacteriaduring inhibition of growth by (Hancock, R.) 69P

Strontium, some aspects of the metabolism of, in lactatingcows (Garner, R. J., Jones, H. G. & Sansom, B. F.)572

Style, crystalline, of lamellibranchs (Bailey, K. & Worboys,B. D.) 487

Succinate, effects of carbon dioxide on the oxidation of, byRicinus mitochondria (Bendall, D. S., Ranson, S. L. &Walker, D. A.) 221

Succinate oxidation, effect of citric acid-cycle intermediateson (Tyler, D. B.) 293

Succinic dehydrogenase in mitochondria of Ricinus, inhibi-tion of, by carbon dioxide (Bendall, D. S., Ranson, S. L. &Walker, D. A.) 221

Succinic oxidase in mitochondria of Ricinus, inhibition of,by carbon dioxide (Ranson, S. L., Walker, D. A. & Clarke,I. D.) 216

Sulphate, incorporation of, into chondroitin sulphate inembryonic chick cartilage (Adams, J. B.) 520

Sulphite, reaction of 2:2'-diaminodiethyl disulphide (cyst-amine) with, at low pH (Cecil, R.) 156

Synovial tissue, concentrations of creatine and phospho-creatine in (Cook, E. R., Thomas, D. P. Page & Dingle,J. T.) 120

Tannins, distribution and deposition of, in heartwoods ofAcacia mollisima and Schinopsis spp. (Roux, D. G. &Evelyn, S. R.) 17

Thiamine, presence of, in yellow pigment of bull semen(White, I. G. & Lincoln, G. J.) 301

2[*S]-Thiohydantoin, metabolism of (Broadhead, G. D. &Kilpatrick, R.) 63P

Thiol group in the 'active site' of creatine phosphokinase(Watts, D. C., Rabin, B. R. & Crook, E. M.) 7P

Thymidine kinases in mammalian tissues (Weissman, S. M.,Paul, J., Thomson, R. Y., Smellie, R. M. S. & Davidson,J. N.) 1 P

Thymus nucleohistone, metal linkages in, and their damageby X-irradiation (Hagen, U.) 56P

Thyroid auto-antigens, biochemical studies of (Roitt, I. M.,Doniach, D. & Couchman, K.) 34P

Thyroid hormones, interaction of, with intra- and extra-cellular proteins (Tata, J. R.) 35P

Tissue cultures, use of, for the study of plant-cell walls(Lamport, D. T. A. & Northcote, D. H.) 52P

Tocopherols, simultaneous determination of ubiquinones,ubichromenols (substance SC) and, in animal tissues(Diplock, A. T., Green, J., Edwin, E. E. & Bunyan, J,)563

Tomato seedlings, effects of chelating agents on roots of(Cocking, E. C.) 51P

Tomato slices, incorporation of [1-'4C]acetate, [2-14C]acetateand 14C02 into lycopene by (Braithwaite, G. D. & Good-win, T. W.) 1

Tri-iodothyroacetic acid, oxygen consumption of circulatinghuman leucocytes after intravenous injection of tri-iodo-thyronine and (Bisset, S. K., Alexander, W. D. & Crooks,J.) 20P

Tri-iodothyronine, oxygen consumption of circulatinghuman leucocytes after intravenous injection of tri-iodothyroacetic acid and (Bisset, S. K., Alexander, W. D.& Crooks, J.) 20P

Triphosphoinositide B, hydrolysis products of, preparedfrom ox brain (Dawson, R. M. C. & Dittmer, J. C.)42P

Triphosphopyridine nucleotide, reduced, effect ofoestradiol-17f on the production of, in rat uterus (Mongkolkul, K. &Grant, J. K.) 46P

Triphosphopyridine nucleotide reductase, photosynthetic,from Chlorella and higher plants (Hill, R. & Bendall, F.)47P

Trypanosoma rhodesiense, L-oa-glycerophosphate dehydro-genase component of oxidase system in (Grant, P. T. &Sargent, J. R.) 48P

Trypanosom,a rhodesiense, properties of L-o-glycerophos-phate oxidase and its role in the respiration of (Grant,P. T. & Sargent, J. R.) 229

Trypsin-catalysed hydrolysis of synthetic substrates, kin-etics of (Elmore, D. T. & Baines, N. J.) 25P

Trypsinogen, mechanism of activation of, by Penicilliumkinase (Hofmann, T.) 26P

Ubichromenols (substance SC), simultaneous determina-tions of tocopherols, ubiquinones and, in animal tissues(Diplock, A. T., Green, J., Edwin, E. E. & Bunyan, J.)563

Ubiquinone, method for determining the concentration of,in mitochondrial preparations (Pumphrey, A. M. &Redfearn, E. R.) 61

Ubiquinone oxidase in heart-muscle preparations (Red-fearn, E. R. & Pumphrey, A. M.) 64

Ubiquinone reactions in heart-muscle preparations, kineticsof (Redfearn, E. R. & Pumphrey, A. M.) 64

Ubiquinone reductase in heart-muscle preparations (Red-fearn, E. R. & Pumphrey, A. M.) 64

Ubiquinones, simultaneous determinations of tocopherols,ubichromenols (substance SC) and, in animal tissues (Dip-lock, A. T., Green, J., Edwin, E. E. & Bunyan, J.)563

Urea, metabolism of, by heart (Menne, F.) 63PUridine diphosphogalacturonic acid, pathway of formation

of, in type XXXIII pneumococci and its importance inthe formation of binary capsulated type III-XXXIIIpneumococci during transformation (Mills, G. T., Smith,E. E. B., Bernheimer, H. P., Austrian, R. & Galloway,B.) 31 P

Urine colloids, separation of, on diethylaminoethylcellulose(Anderson, A. J., Lepper, M. H. & Winzler, R. J.)loP

Urine, direct chromatographic estimation of steroid sul-phates of (Bush, I. E. & Gale, M. M.) IOP

Urine, inhibition of amylase activity of, by citrate (Street,H. V.) 10

Vol. 76 639

INDEX OF SUBJECTSUronic acid, content of, in cartilage and aorta in rabbit

(Grant, R. A., Hathorn, M. & Gillman, T.) 412Uterus, rat, effect of oestradiol-17ft on the production of

reduced triphosphopyTidine nucleotide in (Mongkolkul,K. & Grant, J. K.) 46P

Vitamin D2, '4C-labelled, fate of physiological doses of, innormal and rachitic rats (Kodicek, E. & Ashby, D. R.)14P

Vitamin D2, 14C-labelled, metabolism of, injected intra-cardially into rats (Kodicek, E., Cruickshank, E. M. &

Ashbv, D. R.) 15PVibrio cholerae, action of streptomycin on (Krishna Murti,

C. R.) 362

Waxy-maize starch, action of a-amylase on (Roberts,P. J. P. & Whelan, W. J.) 246

Waxy-maize starch, an a-amylase limit dextrin from (Bines,B. J. & Whelan, W. J.) 253

X-ray-scattering studies, low-angle, of ribonucleic acid insolution (Timasheff, S. N. & Luzzati, V.) 57P

Yeast, baker's, effects of 2:4-dinitrophenol and salicylateon glucose metabolism in (Moses, V. & Smith, M. J. H.)585

Yeast, baker's, soluble nucleotides of (Miettinen, J. K. &

Savioja, T.) 66PYellow pigment of bull semen and its content of riboflavin,

niacin, thiamine and related compounds (White, I. G. &Lincoln, G. J.) 301

Zymo8arcina ventriculi, clastic fission of pyruvic acid in(Arbuthnott, J. P., Bauchop, T. & Dawes, E. A.) 12P

640 1960