The GenoThe genome sequence of Rickettsia prowazekii and the origin of mitochondria.pdfme Sequence of Rickettsia Prowazekii and the Origin of Mitochondria

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  • 8/9/2019 The GenoThe genome sequence of Rickettsia prowazekii and the origin of mitochondria.pdfme Sequence of Ricket

    1/11Nature Macmillan Publishers Ltd 1998

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  • 8/9/2019 The GenoThe genome sequence of Rickettsia prowazekii and the origin of mitochondria.pdfme Sequence of Ricket

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  • 8/9/2019 The GenoThe genome sequence of Rickettsia prowazekii and the origin of mitochondria.pdfme Sequence of Ricket

    4/11Nature Macmillan Publishers Ltd 1998

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    0

    5

    10

    15

    20

    25

    30

    35

    40

    45

    50

    0 500 1,000 1,500 2,000 2,500 3,000 3,500

    Length (bp)

    G +

    C ( % )

  • 8/9/2019 The GenoThe genome sequence of Rickettsia prowazekii and the origin of mitochondria.pdfme Sequence of Ricket

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  • 8/9/2019 The GenoThe genome sequence of Rickettsia prowazekii and the origin of mitochondria.pdfme Sequence of Ricket

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    0

    10

    20

    30

    40

    25-30 30-40 40-50 50-60 60-70 70-80

    Per cent identity

    N u m

    b e r o

    f p r o

    t e i n s

    Energy (91)

    Membrane, transport (35)

    Other (45)

    Translation (106)

    Regulation, splicing (23)Biosynthesis (22)

    Prototheca wickerhamii

    Marchantia polymorpha

    Reclinomonas americana

    Rick ettsia prowazekii

    Aquifex aeolicus

    Escherichia coli

    Borrelia bur g dorferi

    Mycobacterium tuberculosis

    Haemophilus influenzae

    Bacillus subtilis

    Synechocystis sp.

    Cyanophora paradoxa

    Porphyra purpurea

    Helicobacter pylori

    Mitochondria

    -proteobacteria

    Cyanobacteria

    Chloroplast

    100,100

    100,100

    100,100

    100,100

    91,90

    mtDNA

    EFT u -S10- spc -

    Nad11,1,Cox11,3

    97,91

    Reclinomonas americana

    Rickettsia prowazekii

    b

    a

    -S10 -spc- L11-L1-L10-RNAP -RNAP '-S12-S7-EFTu

    S12-S7-EFG L11-L1-L10-L12-RNAP -RNAP '--

  • 8/9/2019 The GenoThe genome sequence of Rickettsia prowazekii and the origin of mitochondria.pdfme Sequence of Ricket

    7/11Nature Macmillan Publishers Ltd 1998

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    cox B-A

    nuo J*-K*-L*-M*

    nuo A*-B-C-D

    atp B-E-X-F atp H-A-G-D-C

    nuo G-H*-I

    sdh C-D-A

    cox A-B

    nuo K*-L*-M*-N*

    sdh C-D-B

    nuo A*-B-C-D-J*

    atp A-G

    nuo G-H* mtDNA

    P r ototheca wick erhamii

    Marchantia polymorpha Reclinomonas americana

    Acanthamoeba castellanii

    Rickettsia prowazekii

    Rhodobacter capsulatus

    Paracoccus denitrificans Escherichia coli

    Thermus thermophilus

    Mycobacterium tuberculosis

    Synechocystissp..Marchantia polymorpha

    Zea maize

    Mitochondria

    -proteobacteria

    Cyanobacteria

    Chloroplast

    100,100

    100,100100,100

    95,73

    100,100

    100,100100,100

    100,100

    Complex I

    Complex II

    Complex IV

    Complex V

    98,95

    Reclinomonas americana

    Rickettsia prowazekii

    a

    b

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