The Grand Challenge of Saving Brains

November 2014

Area of focus is global health

Funded by Government of Canada

Funds innovators from developing countries and Canada

Encourages Integrated Innovation

Catalyzes impact at scale and sustainability

Focuses on results: Saving and improving lives

Bold Ideas. Big Impact. A Better World.

Joseph L. Rotman (pictured top left); Peter A. Singer and the Honourable James Flaherty (pictured bottom right) at the Launch of Grand Challenges Canada on May 3, 2010

Overview

Saving Lives at Birth

Global Mental HealthSaving Brains

Stars in Global Health

Grand Challenges in Global Health

CONFIDENTIAL

The Problem

• Over 200 million children in developing countries are unable to fulfill their developmental potential

Grantham-McGregor et al, Lancet 2007

• Children’s health is a nation’s wealth: healthy child development is the foundation of a vital and productive society with a prosperous and sustainable future

National Scientific Council on the Developing Child 2010

The Challenge

• To develop sustainable products, services and implementation models that protect, promote and nurture healthy child and brain development in the first 1000 days at scale with lasting impact on human capital in low resource settings.

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CONFIDENTIAL

Promote health and nutrition

Protect against

maltreatment and violence

Provide enrichment

and nurturing

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For example:• Support exclusive breastfeeding• Treat micronutrient deficiency• Care for babies born too soon• Reduce exposure to environmental toxins

For example:• Coach parents to

buffer stress• Arm girls with

negotiation skills

For example:• Treat maternal

depression• Integrate stimulation

into child health• Involve fathers in

parenting• Enhance quality of

community nurseries

Saving Brains

Supporting bold ideas to improve early child development in low- and middle-income countries.

Focus Phase: Long-term Impact

Round 1A, Re-enrolment grants:• Launched May 2011• Funded 11 24-month projects, • Total investment: $11.85M

Round 1B, Economic grants:• Launched October 2011• Funded 2 consortia, 18 Months• Total investment: $4.66M

Solution Phase: Scaling

Round 2:• Launched November 2012• 10 24-mo seed projects: $2.7M• 3 34-mo Transition-to-Scale projects: $6.0M• Total investment: $8.7M

Round 3:• Launched October 2013• 13 24-mo seed projects; TTS pending• Includes 3 co-funded Brazilian grants• Total investment to date: $3.5M

Round 4:• Proposals currently under peer review

Saving Brains Investments

+ Stars in Global Health aligned to Saving Brains:

• $3.7M total investment, 34 innovations across 6 rounds 6

Total investments to date: $33.7M invested in 74 projects and a platform to accelerate progress against the challenge

Saving Brains in a sustainable manner, at scale, requires committed, engaged, aligned organizations who can bring their resources and expertise to bear. For example:

• Global partners to support innovations globally

• Regional partners to support innovations within regions of interest

• Implementation partners to inform current needs for innovation and rapidly take up innovations for impact at scale

• Corporate partners to support the scaling of specific innovations aligned with their core business

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Saving Brains Partnership

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