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Promise of NO Glasses! 2017 Jack T. Holladay MD MSEE FACS Page 1 of 6 5/9/2017 JTH 1 The Promise of No Glasses How to Deliver! Jack T. Holladay, MD, MSEE, FACS Clinical Professor of Ophthalmology Baylor College of Medicine Houston, Tx WWW.AAO.ORG 0 AMERICAN ACADEMY OF OPHTHALMOLOGY Financial Disclosure I have the following financial interests or relationships to disclose: Abbott Medical Optics: C; AcuFocus, Inc.: C,O; Alcon Laboratories, Inc.: C; ArcScan: C,O; Carl Zeiss Inc: C; Elenza: C,O; M & S Technologies: C; Oculus, Inc.: C; Visiometrics: C,O; 5/9/2017 JTH 4 www.docholladay.com 5/9/2017 JTH 5 Total BLUR must be < 0.50 D SEQ + CYL < 0.50 D |0.25| + |0.25| = 0.50 D |0.50| + 0.00 = 0.50 D 0.00 + |0.50| = 0.50 D 5/9/2017 JTH 6 Requirements Centration Accurate Biometry – Optical (IOL Master or LenStar, …) Accurate K’s- Repeatable 4 th Generation Formula (WTW) Personalized Lens Constant Eliminate Corneal Astigmatism 5/9/2017 JTH 7 Multifocal IOL Optimal Location Cannot place on Pupil Center & Visual Axis (near P1) where axial ray is perpendicular to foveola. Optimal location is different for each patient and somewhere between Pupil Center & P1.

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Promise of NO Glasses! 2017

Jack T. Holladay MD MSEE FACS Page 1 of 6

5/9/2017 JTH 1

The Promise of No Glasses

How to Deliver!

Jack T. Holladay, MD, MSEE, FACSClinical Professor of Ophthalmology

Baylor College of MedicineHouston, Tx

WWW.AAO.ORG

0

AMERICAN ACADEMY OF OPHTHALMOLOGY

Financial Disclosure I have the following financial interests or relationships to disclose: Abbott Medical Optics: C; 

AcuFocus, Inc.: C,O; 

Alcon Laboratories, Inc.: C; 

ArcScan: C,O; 

Carl Zeiss Inc: C; 

Elenza: C,O;

M & S Technologies: C; 

Oculus, Inc.: C; 

Visiometrics: C,O; 

5/9/2017 JTH 4

www.docholladay.com

5/9/2017 JTH 5

Total BLUR must be < 0.50 D

SEQ + CYL < 0.50 D

|0.25| + |0.25| = 0.50 D

|0.50| + 0.00 = 0.50 D

0.00 + |0.50| = 0.50 D

5/9/2017 JTH 6

Requirements Centration

Accurate Biometry – Optical (IOL Master or LenStar, …)

Accurate K’s- Repeatable

4th Generation Formula (WTW)

Personalized Lens Constant

Eliminate Corneal Astigmatism5/9/2017 JTH 7

Multifocal IOLOptimal Location

Cannot place on Pupil Center & Visual Axis (near P1) where axial ray is perpendicular to foveola.

Optimal location is different for each patient and somewhere between Pupil Center & P1.

Promise of NO Glasses! 2017

Jack T. Holladay MD MSEE FACS Page 2 of 6

5/9/2017 JTH 9

Horizontal Angle & Alpha & Kappa

PCVA

< Κ

Angle Kappa on IOL Master, LenStar and penlight ~ 0.33 mm

If > 0.60 mm then concern!

●Karhanová M, Marešová K, Pluháček F, Mlčák P, Vláčil O, Sín M. Cesk Slov Oftalmol. The importance of angle kappa for centration of multifocal intraocular lenses. 2013 Jun;69(2):64-8. [Article in Czech]● G Prakash, DR Prakash, A Agarwal, DA Kumar, A Agarwal and S Jacob. Predictive factor and kappa angle analysis for visual satisfactions in patients with multifocal IOL implantation. Eye (2011) 25, 1187–1193

5/9/2017 JTH 10

LENSTAR – HAAG-STREIT

Ignore Sign … ADD PCX & PCY MAGNITUDES < 0.6 mm

5/9/2017 JTH 11

IOL MASTER 500 – ZEISSVersion ≥ 7.1

Ignore Sign … ADD Px & Py MAGNITUDES < 0.6 mm

Data Screening IdentifiesMeasurement Error - Repeat Binocular AL difference > 0.3 mm

K difference > 1.0 D

IOL power difference > 1.0 D

Monocular AL Signal/Noise (S/N) Ratio < 2.0

K Std Dev (σ) > 0.20 D 5/9/2017 JTH 13

J Cataract Refract Surg 2011; 37:2018–2027

Promise of NO Glasses! 2017

Jack T. Holladay MD MSEE FACS Page 3 of 6

5/9/2017 JTH 14

Wang/Koch Linear 1-ctr Regression to

compensate for Long Eyes (> 25)

Go half-way between

Measured 36 34 mm

H1 Haigis

SRKT HofferQ

5/9/2017 JTH 15

Requirements Centration

Accurate Biometry – Optical

(IOL Master or LenStar)

Accurate K’s- Repeatable

4th Generation Formula (WTW)

Personalized Lens Constant

Eliminate Corneal Astigmatism

5/9/2017 JTH 16

If SD for K’s> ± 0.20 D (0.030 mm = 30 µm)

Test for Dry Eye

ToPography/ToMography5/9/2017 JTH 17

IOL Master

5/9/2017 JTH 18

LenStar

5/9/2017 JTH 19

Corneal Quality

HO RMS CORNEALwavefront error over a 6 mm zone < 0.50 µmMean = 0.38 µm

Promise of NO Glasses! 2017

Jack T. Holladay MD MSEE FACS Page 4 of 6

5/9/2017 JTH 20

Corneal QualityHO RMS CORNEAL wavefront

error over a 6 mm zone < 0.50 µm

Normal = 0.38 ± 0.14 µm

PO Lasik Happy = 0.58 ± 0.21µm

PO Laski Unhappy = 1.31 ± 0.58 µmMcCormick GJ, Porter J, Cox IG, MacRae S. Higher-order aberrations in eyes with irregular corneas after laser refractive surgery. Ophthalmology. 2005 Oct;112(10):1699-709 5/9/2017 JTH 21

IOL Power Calculation(Zone not Ring – 14K not 24) Pentacam can measure FRONT &

BACK SURFACE POWER

Can Calculate: Equivalent K-Reading (EKR65)

65% Mean, Peak & Average

5/9/2017 JTH 22

IOL Calcs – Abnormal Cornea(Use 65% MEAN EKR) Post Refractive Surgery

Post PKP

Keratoconus

Corneal Scar

Any Irregular Astigmatism5/9/2017 JTH 23

Requirements Centration

Accurate Biometry – Optical

(IOL Master or LenStar)

Accurate K’s- Repeatable

4th Generation Formula (7 variables)

Personalized Lens Constant

Eliminate Corneal Astigmatism

5/9/2017 JTH 24

Measurements taken forPredictors of ELP

Holladay 2, Olsen 2, Barrett 2

Axial Length

Average K (Pre R S)

Horizontal WTW

ACD

LT

Pre-op Ref (Adult before Cat)

Age

5/9/2017 JTH 25

CONCLUSION: 9 EYES

Ant

erio

r S

egm

ent S

ize

Axial LengthShort Normal Long

Large

Normal

Small

Megalocornea Large Eye

+ axial Megalocornea Buphthalmos

hyperopia Megalocornea

+ axial myopia

axial hyperopia normal axial myopia

Small eye Microcornea

Nanophthalmia Microcornea + axial mopia

(20%)

(10%)(2%)

(2%)

(80%) (96%) (90%)

(0%)

(0%)

Promise of NO Glasses! 2017

Jack T. Holladay MD MSEE FACS Page 5 of 6

5/9/2017 JTH 26

99% Contribution to PEVari. % SD (D) MAE (D)

P ELP 35% 0.31 0.24

Ref 27% 0.39 0.31

AL 17% 0.31 0.24

K 12% 0.18 0.14

Pupil 8% 0.21 0.165/9/2017 JTH 27

PE is always Gaussian (NL)

Average Excellent Best

SD 0.50 D 0.40 D 0.31 D

MAE 0.40 D 0.32 D 0.24 D

± 0.50 67% 79% 90%

5/9/2017 JTH 28

Requirements Centration

Accurate Biometry – Optical

(IOL Master or LenStar)

Accurate K’s- Repeatable

4th Generation Formula (WTW)

Personalized Lens Constant

Eliminate Corneal Astigmatism5/9/2017 JTH 29

Personalized Lens Constant Never use Manufacturer’s Constant

except to start 20 to 40 cases and continue Factors IOL Style Lens placement, OVDs Post op medications Biometer, keratometer, …

5/9/2017 JTH 30

Requirements Centration

Accurate Biometry – Optical

(IOL Master or LenStar)

Accurate K’s- Repeatable

4th Generation Formula (WTW)

Personalized Lens Constant

Eliminate Corneal Astigmatism5/9/2017 JTH 31

Ideal Toric IOL Calcs Accurate corneal power and astigmatism … repeat

is SD > 0.020 D (0.030 mm = 30 µm)

Exact Toric Calculator (not a constant ratio of corneal astigmatism to toricity 1.46)

Proper Surgically Induced Astigmatism (SIA) for incision location and magnitude and axis of PreOpastigmatism … must account for ATR over 3 to 6 months PostOp

Results will be greater than 80% within 0.50 D

Promise of NO Glasses! 2017

Jack T. Holladay MD MSEE FACS Page 6 of 6

5/9/2017 JTH 32

Requirements Centration

Accurate Biometry – Optical (IOL Master or LenStar)

Accurate K’s- Repeatable

4th Generation Formula (WTW)

Personalized Lens Constant

Eliminate Corneal Astigmatism

!Thank You!