The treatment of Lyme disease The treatment of Lyme disease

in the ASD childin the ASD child

Dietrich Klinghardt MD, PhDDietrich Klinghardt MD, PhD

April 2010April 2010

Fetal borrelia can causefetal death, growthretardation, cardiacanomolies, hydrocephalus,blindness, neonatal resp.distress, SIDSand toxemic pregnancy.(Rheum Dis Clin North Am.1989 Nov;15(4):657-77)

LYME BORRELIOSIS:GREAT IMITATORLyme can cause cardiomyopathy,CHF, perimyocarditis,cardiac arrhythmias,AV block and otherconduction disturbances.(Eur Heart J.1991 Aug;12 Suppl D:73-5)

LYME BORRELIOSIS:

Lyme is a spirochetal illness resembling syphilis.

Can mimic MS, myelopathy,polyneuropathy,brain tumor,encephalopathy.(Neurosurgery.1992May;30(5):769-73)

Can cause meningitis,encephalitis,neuritis,mania,depression, OCD,schizophrenia, anorexia, dementia.(Am J Psychiatry. 1994 Nov;151(11):1571-83)

GREAT IMITATOR

LYME BORRELIOSIS:TRANSMISSION

• Mosquitos , fleas, stinging flies

(horse flies), spider bites

• ticks

• Blood transfusions

• Sexual intercourse

• Trans-placental transfer to the

fetus

• Breast feeding

• Food

• Saliva (kissing), contaminated

utensils and telephones

Borrelia (bacteria)

Babesia (protozoa)

Bartonella (bacteria)

Ehrlichia (rickettsia)

Coxiella (rickettsia)

Mycoplasma (L-form)

Viruses (HHV-

6,CMV,EBV, Borna,

XMRV)

LYME Co-Infections CO-INFECTIONS

Opportunistic InfectionsOpportunistic Infections

Giardia and amoebasGiardia and amoebas Worms – most common: Varestrongylus Worms – most common: Varestrongylus

Klapowi (lungworm)Klapowi (lungworm) Mold/yeastMold/yeast All human pathogenic viruses (over 2000) All human pathogenic viruses (over 2000)

– most ommon: Borna Virus, herpes family – most ommon: Borna Virus, herpes family and XMRVand XMRV

Strep and oral bacteria (chronic tonsillitis)Strep and oral bacteria (chronic tonsillitis)

Biological treatment of Lyme disease in ASD Biological treatment of Lyme disease in ASD ChildrenChildren

The treatment of Lyme disease requires 4 distinctive steps:The treatment of Lyme disease requires 4 distinctive steps:

1.1. Decreasing toxic body burden/unloading the system Decreasing toxic body burden/unloading the system

2.2. Improving disturbed physiologyImproving disturbed physiology

3.3. Decreasing microbial countDecreasing microbial count

4.4. ImmunemodulationImmunemodulation

1. Unloading the system- detox1. Unloading the system- detox

Microbes establish themselves by successfully Microbes establish themselves by successfully modulating the host’s immune system. They do this with modulating the host’s immune system. They do this with a variety of mechanisms. One of them is the excretion of a variety of mechanisms. One of them is the excretion of biotoxins and neural messenger molecules. Several of biotoxins and neural messenger molecules. Several of these block the host’s innate mechanisms and enzyme these block the host’s innate mechanisms and enzyme systems capable to eliminate these substances (detox systems capable to eliminate these substances (detox enzymes). These same blocked enzymes are the ones enzymes). These same blocked enzymes are the ones we use to detoxify mercury and other environmental we use to detoxify mercury and other environmental toxins. The same enzymes may already be toxins. The same enzymes may already be compromised by genetic polymorphisms.compromised by genetic polymorphisms.

The net effect: the host looses the ability to eliminate The net effect: the host looses the ability to eliminate toxins and becomes increasingly contaminated with a toxins and becomes increasingly contaminated with a spectrum of physiological, biochemical, emotional and spectrum of physiological, biochemical, emotional and social findings congruent with ASD.social findings congruent with ASD.

Solution: use detox agents and methods in low EMF Solution: use detox agents and methods in low EMF environmentenvironment

1. Detox agent options: we use the same agents 1. Detox agent options: we use the same agents that remove metals to also remove biotoxinsthat remove metals to also remove biotoxins

Chlorella, CVE and CGFChlorella, CVE and CGF Matrix Metals spray (nanonized chlorella and cilantro)Matrix Metals spray (nanonized chlorella and cilantro) Cilantro tinctureCilantro tincture Micro Silica (silica bound SH-groups)Micro Silica (silica bound SH-groups) OSR (glutathion increase)OSR (glutathion increase) Aminoacids: methionine, taurine, glycine, BCAAsAminoacids: methionine, taurine, glycine, BCAAs AlginateAlginate Plant stem cell preparation (“7 flowerbuds” from BioPure)Plant stem cell preparation (“7 flowerbuds” from BioPure) Chemicals: homeopathic 48 day detox packChemicals: homeopathic 48 day detox pack Laser detoxLaser detox Oral DMPS, DMSAOral DMPS, DMSA Subcutaneous injections with DMPSSubcutaneous injections with DMPS

1.1. Decreasing toxic body Decreasing toxic body burden/unloading the system: burden/unloading the system: the ASD child cannot eliminate toxins in the EMF the ASD child cannot eliminate toxins in the EMF environmentenvironment

Lower EMF exposure :Lower EMF exposure : Night time technology: Night time technology: turn off all fuses, sleep sanctuary, turquoiseturn off all fuses, sleep sanctuary, turquoise light/photon wave to increase melatonin and non-rem Delta sleep)light/photon wave to increase melatonin and non-rem Delta sleep) Day-time technology: Day-time technology: no wireless in home, no chordless phones. No bright lights atno wireless in home, no chordless phones. No bright lights at home. DVD/computer set on low contrast/volumehome. DVD/computer set on low contrast/volume Stetzer filters, Renzo chip, consider silver coated clothing for EMF Stetzer filters, Renzo chip, consider silver coated clothing for EMF

protectionprotection

Other sleep issues: Other sleep issues: Non-toxic/allergenic bedding material (cave: flameNon-toxic/allergenic bedding material (cave: flame retardants/PBDEs)retardants/PBDEs) Avoid light/noise pollution at night Avoid light/noise pollution at night bitter orange (Andrea Lalama) bitter orange (Andrea Lalama) melatoninmelatonin

1. Unloading the system - detox1. Unloading the system - detoxSelf Help:Self Help:• Colon hydrotherapy/enemas and lymphatic drainage, rhythmic cranial and liver Colon hydrotherapy/enemas and lymphatic drainage, rhythmic cranial and liver

compressioncompression• Breathing retraining (Linda Scotson Technique)Breathing retraining (Linda Scotson Technique)• Dry skin brushing and warm/cold showersDry skin brushing and warm/cold showers• Swedish sauna and Toxaway ionic foot bathSwedish sauna and Toxaway ionic foot bath• Cilantro, chlorella, CGF, CVE, Matrix MetalsCilantro, chlorella, CGF, CVE, Matrix Metals

Detect and resolve Detect and resolve interference fieldsinterference fields: : • ScarsScars• Chronic Tonsillitis: regenerative cryotherapy (Chronic Tonsillitis: regenerative cryotherapy (www.kryopraxis.de)) Zithromax 500 mg once a weekZithromax 500 mg once a week Quintessence (BioPure)Quintessence (BioPure) Sanum remedies: Notakehl and SanPseu for 6 weeks, then Sancombi for Sanum remedies: Notakehl and SanPseu for 6 weeks, then Sancombi for 9 months9 months

Remove “Remove “allergenic triggersallergenic triggers” and ongoing toxin exposure (” and ongoing toxin exposure (from from environment )environment )

• Food allergies (Doris Rapp MD)Food allergies (Doris Rapp MD)• Volatile organic compounds from carpets, furniture and paintsVolatile organic compounds from carpets, furniture and paints• new car smell (phthalates)new car smell (phthalates)• Newspaper and office printing inkNewspaper and office printing ink• Work/profession related compounds from parents, Chinese toysWork/profession related compounds from parents, Chinese toys• Check the soil in garden (lead) and playground materialsCheck the soil in garden (lead) and playground materials

1. Unloading the system - detox1. Unloading the system - detox

Removing psychological toxinsRemoving psychological toxinsParents do the work:Parents do the work:• 20 minute writing exercise to overcome past trauma20 minute writing exercise to overcome past trauma• Family constellation work to resolve trans-generational Family constellation work to resolve trans-generational

issuesissues• Applied Psycho-Neurobiology to resolve conflicts and Applied Psycho-Neurobiology to resolve conflicts and

severe traumasevere trauma• Regular time spend in healthy natureRegular time spend in healthy nature• Regular massageRegular massage• Qi Gong, Tai Chi or MeditationQi Gong, Tai Chi or Meditation

Removing structural blockagesRemoving structural blockages• Optimize the dental occlusion to restore cranial Optimize the dental occlusion to restore cranial

lymphatic pumplymphatic pump• Craniosacral therapy to improve fluid dynamics in CNSCraniosacral therapy to improve fluid dynamics in CNS• Visceral manipulation to improve organ functionVisceral manipulation to improve organ function

2. Improving disturbed physiology and biochemistry2. Improving disturbed physiology and biochemistry(vitality, detox, immune responses, tissue repair)(vitality, detox, immune responses, tissue repair)

• Every child should receive inhalation with singlet oxygen energy Every child should receive inhalation with singlet oxygen energy (Valkion) to increase ATP, NADPH, glutathione. Increase ATP with (Valkion) to increase ATP, NADPH, glutathione. Increase ATP with D-galactose D-galactose

• HPU urine test /address deficiencies (Core)HPU urine test /address deficiencies (Core)• Assessment via lab work or ART – correct what is missing and what Assessment via lab work or ART – correct what is missing and what

is too much (minerals, fatty acids, aminoacids, hormones and is too much (minerals, fatty acids, aminoacids, hormones and electrolytes, glutathione, sulfur, etc.)electrolytes, glutathione, sulfur, etc.)

• Genetic testing: find minimal bypass nutrition to correct for SNPs or Genetic testing: find minimal bypass nutrition to correct for SNPs or gene deletions/mutationsgene deletions/mutations

• Diet: gluten and casein free diet, Specific carbohydrate Diet: gluten and casein free diet, Specific carbohydrate diet,Metabolic typing, blood group diet or ART based dietdiet,Metabolic typing, blood group diet or ART based diet

• Common deficiencies in Lyme: magnesium: consider to give Common deficiencies in Lyme: magnesium: consider to give transdermal or via injection. Oral Mag feeds otherwise untreated transdermal or via injection. Oral Mag feeds otherwise untreated spirochetes. Iron displacement in the brain (Zamboni)spirochetes. Iron displacement in the brain (Zamboni)

• Copper, zinc and iron are spent by macrophages and appear in Copper, zinc and iron are spent by macrophages and appear in oxidized form in hair and serum, giving the wrong appearance of oxidized form in hair and serum, giving the wrong appearance of excessexcess

2. Improving distrubed biochemistry and physiology: 2. Improving distrubed biochemistry and physiology: KPU/HPUKPU/HPU

Over 80% of our Lyme patients have developed HPU (hemo-pyrrol-lactam-Over 80% of our Lyme patients have developed HPU (hemo-pyrrol-lactam-uria). The term falsely used in most US literature is KPU (krypto-pyrrol-uria)uria). The term falsely used in most US literature is KPU (krypto-pyrrol-uria)

HPU disarms the immune system by catastrophic depletion of zinc, HPU disarms the immune system by catastrophic depletion of zinc, manganese, arachidonic acid, histamin, taurine. manganese, arachidonic acid, histamin, taurine.

These losses are hard to detect with any current technology (only bone and These losses are hard to detect with any current technology (only bone and CNS biopsies are reliable. CNS biopsies are reliable.

I use a 24 hr urine sample (kept in fridge). 1 capsule /day “core” (Biopure) I use a 24 hr urine sample (kept in fridge). 1 capsule /day “core” (Biopure) treats a 5 year old (zinc, B6, chromium, biotin, molybdenum, taurine)treats a 5 year old (zinc, B6, chromium, biotin, molybdenum, taurine)

Labs to consider: Labs to consider: HPU/KPU urine test (Vitamin Diagnostics)HPU/KPU urine test (Vitamin Diagnostics)

• alkaline phosphatase low normalalkaline phosphatase low normal• copper: zinc ration greater then 1 in hair and urinecopper: zinc ration greater then 1 in hair and urine• low Omega 6 in red cell membrane fatty acid testlow Omega 6 in red cell membrane fatty acid test• white blood cell zinc, red cell copper levelwhite blood cell zinc, red cell copper level

If KPU is treated first and the system is restored to normal levels (4-8If KPU is treated first and the system is restored to normal levels (4-8months), Borrelia, Bartonella-like organisms and Babesia respond tomonths), Borrelia, Bartonella-like organisms and Babesia respond tomuch milder interventions without significant Herxes or problemsmuch milder interventions without significant Herxes or problems

2. Improving disturbed physiology and biochemistry2. Improving disturbed physiology and biochemistry (vitality, detox, immune responses, tissue repair)(vitality, detox, immune responses, tissue repair)

NeurophysiologyNeurophysiology• Give the brain healthy rhythms: CES (V.Soobiah)Give the brain healthy rhythms: CES (V.Soobiah)• Listening program, color therapy, meridian tapping Listening program, color therapy, meridian tapping

therapies (MFT)therapies (MFT)• Listen to Lyme entrainment CDsListen to Lyme entrainment CDs• Spend time in natureSpend time in nature• Avoid disturbing EMF (chordless phones, cell phones, Avoid disturbing EMF (chordless phones, cell phones,

wireless technology, home near airport (radar), computerwireless technology, home near airport (radar), computer

ExerciseExercise• StretchingStretching• Movement (dancing, walking, running)Movement (dancing, walking, running)• Floor timeFloor time

Sequencing Treatment: Sequencing Treatment: the Lyme ABCthe Lyme ABC

There is an inherent order in which the microbes should be There is an inherent order in which the microbes should be treated. If the order is correct, gentle methods work. treated. If the order is correct, gentle methods work. Treatment should always combine electromagnetic Treatment should always combine electromagnetic interventions, using specific microbial inhibition frequencies interventions, using specific microbial inhibition frequencies (KMT CD- based sound technology) with the appropriate (KMT CD- based sound technology) with the appropriate herb, antibiotic or other antimicrobial strategy. It should also herb, antibiotic or other antimicrobial strategy. It should also always be combined with a toxin elimination program, good always be combined with a toxin elimination program, good psychotherapy and general life style hygiene (all the stuff, that psychotherapy and general life style hygiene (all the stuff, that alternative Medicine stands for).alternative Medicine stands for).

Principle: start with the large opportunistic invaders. Go from Principle: start with the large opportunistic invaders. Go from large to small. Treat Borrelia lastlarge to small. Treat Borrelia last

A.A. Worms: Worms: (Ascaris, Taenia, Threadworms)(Ascaris, Taenia, Threadworms)

Lab: hopeless in the US, PCR based parasite tests are less often false Lab: hopeless in the US, PCR based parasite tests are less often false negative, saliva test for worms is sometimes helpfulnegative, saliva test for worms is sometimes helpful

Physical exam: helminth patternPhysical exam: helminth pattern Treat by therapeutic trialTreat by therapeutic trial Rizol GammaRizol Gamma Salt (12 grams/day) and Vit C Salt (12 grams/day) and Vit C www.lymephotos.com Alternatives: Arise and Shine program, Sputnik, Alinia, Biltricide and Alternatives: Arise and Shine program, Sputnik, Alinia, Biltricide and

AlbenzaAlbenza I often use Biltricide for 3 days (2 tbl. Tid), then Nitazoxanide 1000 mg I often use Biltricide for 3 days (2 tbl. Tid), then Nitazoxanide 1000 mg

bid for 20 days, then alternate Alinia and Biltricide only 2-3 days per bid for 20 days, then alternate Alinia and Biltricide only 2-3 days per week for 3 months. Only Albendazole and Nitazoxanide cross the week for 3 months. Only Albendazole and Nitazoxanide cross the blood brain barrierblood brain barrier

Larval stages (or mature worms) in lung: Inhalation with alcohol Larval stages (or mature worms) in lung: Inhalation with alcohol (L.Klapow protocol) or iodine: 4 drops SSKI in Omron hand-held (L.Klapow protocol) or iodine: 4 drops SSKI in Omron hand-held battery powered inhaler once dailybattery powered inhaler once daily

(source: (source: www.MarksMarinePharmacy, , www.magic pharma.com) pharma.com)

B. Protozoae: B. Protozoae: Babesia, Toxoplasmosis, Gardia, Babesia, Toxoplasmosis, Gardia, Amoebas and TrichomonasAmoebas and Trichomonas

Rizol GammaRizol Gamma Neem (use energized version/Biopure)Neem (use energized version/Biopure) Organic freeze dried garlicOrganic freeze dried garlic ArtemisininArtemisinin MMSMMS TinidazoleTinidazole Nitazoxanide (Alinia)Nitazoxanide (Alinia) AlbendazoleAlbendazole MepronMepron Riamet (Novartis)Riamet (Novartis)

C. Strep infections (often behind some mental symptoms)C. Strep infections (often behind some mental symptoms)

Enderlein remedies (Notakehl, Sanukehl Pseu, Enderlein remedies (Notakehl, Sanukehl Pseu, Sankombi, Arthrokehlan A)Sankombi, Arthrokehlan A)

Conventional tonsilectomyConventional tonsilectomy Regular manual drainageRegular manual drainage Neural therapy injections with procaine and ozone (tonsil Neural therapy injections with procaine and ozone (tonsil

program)program) gargle/mouth wash with MMS, Rizol Gamma, Oxogargle/mouth wash with MMS, Rizol Gamma, Oxo Regenerative Cryotherapy (www.kryopraxis.de)Regenerative Cryotherapy (www.kryopraxis.de) Zithromax 500 mg once weekly ( dosage for 5 year old)Zithromax 500 mg once weekly ( dosage for 5 year old)

E. The herpes family, XMRV and BornaE. The herpes family, XMRV and Borna Rizol ZetaRizol Zeta Quintessence (5 herbs/Biopure)Quintessence (5 herbs/Biopure) Freeze dried garlicFreeze dried garlic AndrographisAndrographis St John’s Wort, olive leaf, monolaurinSt John’s Wort, olive leaf, monolaurin KMT-micro-current deactivationKMT-micro-current deactivation Alternatives: thymus extracts (ProBoost)Alternatives: thymus extracts (ProBoost) mushroom extractsmushroom extracts Ayurvedic herbs (Indian Gooseberry,Chebulic and Beleric Ayurvedic herbs (Indian Gooseberry,Chebulic and Beleric

myrobalan) myrobalan) Chapparal extracts Chapparal extracts Valtrex and ValcyteValtrex and Valcyte Artemisinin (XMRV)Artemisinin (XMRV)

F. Yeast/MoldF. Yeast/Mold::

freeze dried organic garlic freeze dried organic garlic KMT micro-current desensitizationKMT micro-current desensitization Rizol Alpha and GammaRizol Alpha and Gamma Nystatin, Amphotericin B, Fluconazole, Itra- Nystatin, Amphotericin B, Fluconazole, Itra-

and Voriconazole (antifungals have strong and Voriconazole (antifungals have strong anti-spirochete effects)anti-spirochete effects)

Eliminate food allergies/no grain dietEliminate food allergies/no grain diet Clean up the home (propolis vaporizer, matrix Clean up the home (propolis vaporizer, matrix

microbe spray)microbe spray)

G. MycoplasmaG. Mycoplasma::

QuintessenceQuintessence Rizol Gamma, Epsilon and MyRizol Gamma, Epsilon and My Freeze dried garlicFreeze dried garlic MMSMMS APN desensitizationAPN desensitization Enzymes Enzymes Alternative: antibioticsAlternative: antibiotics

H. Borrelia, Rickettsia, Bartonella, Brucella, H. Borrelia, Rickettsia, Bartonella, Brucella, EhrlichiosisEhrlichiosis

Rizols (Borrelia: Epsilon, Lambda and Gamma, Bartonella: My Rizols (Borrelia: Epsilon, Lambda and Gamma, Bartonella: My (effective in ALS)(effective in ALS)

Quintessence Herbs: Andrographis, Stephania Root, Japanese Quintessence Herbs: Andrographis, Stephania Root, Japanese Knot Weed, Smilax, Red Root Knot Weed, Smilax, Red Root

Teasel root (body pain) Teasel root (body pain) Homeopathic Lyme co-infection nosode (BioPure)Homeopathic Lyme co-infection nosode (BioPure) New herbal compounds from W.AndersonNew herbal compounds from W.Anderson Bee-venom, niacin and magnesiumBee-venom, niacin and magnesium Liposomal artemisininLiposomal artemisinin MFT (mental field therapy) and APNMFT (mental field therapy) and APN Alternatives: J.Burrascano M.D. antibiotic protocols, ozone Alternatives: J.Burrascano M.D. antibiotic protocols, ozone

therapy, UV-Btherapy, UV-B

Klinghardt Lyme CocktailKlinghardt Lyme Cocktail

This remedy is based on 150 lbs body weight . The dosage has to be adjusted according to the weight ofThis remedy is based on 150 lbs body weight . The dosage has to be adjusted according to the weight of

the child. The KLC has helped many autistic children to improve significantly the child. The KLC has helped many autistic children to improve significantly

200-400 mg Artemisinin, 100 mg OSR (glutathion), 10 ml Phopsholipid Exchange in blender at high 200-400 mg Artemisinin, 100 mg OSR (glutathion), 10 ml Phopsholipid Exchange in blender at high speedspeed

to make liposomal artemisinin (detox, anti-viral, anti-Babesia, anti-Lyme, shuttle agent, biofilm breaker) to make liposomal artemisinin (detox, anti-viral, anti-Babesia, anti-Lyme, shuttle agent, biofilm breaker)

Then add Then add D-galactose : 5 grams (increases ATP dramatically)D-galactose : 5 grams (increases ATP dramatically) 10 -20 drops 20 % Propolis Tincture (anti-viral)10 -20 drops 20 % Propolis Tincture (anti-viral) Quintessence (Lyme, Ehrlichia, Bartonella)Quintessence (Lyme, Ehrlichia, Bartonella) 15 ml Rechtsregulat (enzyme mix to break biofilm)15 ml Rechtsregulat (enzyme mix to break biofilm) MicroSilica 100 mgMicroSilica 100 mg Co-curcumin (Ayush Herbs): 1 tsp plus pippli 2 caps (pepper to increase absorbtion)Co-curcumin (Ayush Herbs): 1 tsp plus pippli 2 caps (pepper to increase absorbtion) Vit C powder 2000 mgVit C powder 2000 mg Acai powder (anti-microbial, anti-oxidant) 1 tspAcai powder (anti-microbial, anti-oxidant) 1 tsp Mucuna powder 1 tsp (increases L-Dopa for language and motor development)Mucuna powder 1 tsp (increases L-Dopa for language and motor development) ½ glass grapefruit juice (important for artemisinin absorbtion)½ glass grapefruit juice (important for artemisinin absorbtion) ½ glass water½ glass water Optional: Optional: GSE 10 drops - grapefruitseed extract ( anti-microbial, anti-biofilm)GSE 10 drops - grapefruitseed extract ( anti-microbial, anti-biofilm) freeze dried garlic 4 capsulesfreeze dried garlic 4 capsules Energized Neem: 2 caps three times/dayEnergized Neem: 2 caps three times/day Drink this amount twice daily, 5 days on, 2 days off. 3 weeks on, 1 week off. Most products from Drink this amount twice daily, 5 days on, 2 days off. 3 weeks on, 1 week off. Most products from

BioPure (425 462 8414 - BioPureUS@aol.com) BioPure (425 462 8414 - BioPureUS@aol.com)

3. Decreasing the pathogen count3. Decreasing the pathogen count

Treatment of Lyme with ozonated plant oils (rizols). Rizols haveTreatment of Lyme with ozonated plant oils (rizols). Rizols havestrong and specific anti-microbial properties, no known adverse longstrong and specific anti-microbial properties, no known adverse longterm effects, are relatively inexpensive and are pleasant to take.term effects, are relatively inexpensive and are pleasant to take.They have been used successfully since 1905They have been used successfully since 1905

1: treat 1: treat parasites, mold and anaerobesparasites, mold and anaerobes Rizol Gamma (effective dose: 15-20 drops tid)Rizol Gamma (effective dose: 15-20 drops tid)

2: treat both RNA (Borna, etc.) and DNA (HHV-6, EBV, etc.) 2: treat both RNA (Borna, etc.) and DNA (HHV-6, EBV, etc.) virusesviruses: Rizol : Rizol Zeta (20 drops tid)Zeta (20 drops tid)

3: when on full dose of Gamma and Zeta, treat 3: when on full dose of Gamma and Zeta, treat BabesiaBabesia: : acidified sodium chlorite (“MMS”): 15 drops 1 hour apart, 2 days in a row, acidified sodium chlorite (“MMS”): 15 drops 1 hour apart, 2 days in a row,

once weekly for 4 – 8 weeks. Or: Oxo – 2 caps t.i.d.once weekly for 4 – 8 weeks. Or: Oxo – 2 caps t.i.d.

4: after 2 months on full treatment: stop or reduce Rizol Gamma and treat 4: after 2 months on full treatment: stop or reduce Rizol Gamma and treat Bartonella: Bartonella: Rizol My (20 drops tid)Rizol My (20 drops tid)

5: after 2 months reduce dose of rizols Zeta and My to 10 drops tid and treat 5: after 2 months reduce dose of rizols Zeta and My to 10 drops tid and treat spirochetesspirochetes: add Rizol Epsilon and Jota, 10 drops tid each: add Rizol Epsilon and Jota, 10 drops tid each

Always follow rizol with adsorbent (Always follow rizol with adsorbent (biosorptionbiosorption): chlorella (20 tbl), chitosan ): chlorella (20 tbl), chitosan (1-2 caps), zeolite (1 tsp) or charcoal (2 caps)(1-2 caps), zeolite (1 tsp) or charcoal (2 caps)

3. Decreasing the pathogen count3. Decreasing the pathogen count : the rizols : the rizols

Rizol-GammaRizol-Gamma70% Rizol-raw material (ozonated castor oil treated with high voltage 70% Rizol-raw material (ozonated castor oil treated with high voltage

electrolysis)electrolysis)10 % clove oil10 % clove oil10 % oil of artemesia 10 % oil of artemesia 10 % black walnut oil10 % black walnut oil

Rizol-ZetaRizol-Zeta69,3 % Rizol-raw material69,3 % Rizol-raw material10,0 % oil of artemesia annua10,0 % oil of artemesia annua10,0 % clove oil10,0 % clove oil 5,0 % black cumin oil5,0 % black cumin oil 3,0 % moxa oil3,0 % moxa oil 1,8 % walnut oil1,8 % walnut oil 0,9 % oil of majoram0,9 % oil of majoram

3. Decreasing the pathogen count3. Decreasing the pathogen count

Yearbooks of the Karl und Veronica Carstens-foundationYearbooks of the Karl und Veronica Carstens-foundationAdress: Am Deimelsberg 36 45276 Essen, Tel. 0201-563050Adress: Am Deimelsberg 36 45276 Essen, Tel. 0201-563050

3. Decreasing the pathogen count3. Decreasing the pathogen count Carstens Report/Research by Gerhard Steidl PhD: Active Carstens Report/Research by Gerhard Steidl PhD: Active

oxygen against pathogenic anaerobes -properties and oxygen against pathogenic anaerobes -properties and research resultsresearch results

In natureIn natureHumans and animalsHumans and animals::ImmunsystemImmunsystemRespiratory chainRespiratory chainCytochrome P450Cytochrome P450(detox enzymes)(detox enzymes)

Plants:Plants:EndoperoxideEndoperoxide <<<>>>> <<<>>>>

SyntheticSynthetic

PeroxidesPeroxidesH2O2H2O2OzoneOzoneMagnesiumperoxideMagnesiumperoxideOrganic PeroxidesOrganic Peroxides

Ozonide (rizole)Ozonide (rizole)

Endoperoxides and Ozonides

are identical in structure and properties

3. Decreasing the pathogen count3. Decreasing the pathogen count : microbial : microbial inhibition by rizolsinhibition by rizols

1. Inhibition (culture medium)1. Inhibition (culture medium)Pathogen: Candida Aspergillus Aerobe B. Anaerobe B.Pathogen: Candida Aspergillus Aerobe B. Anaerobe B.Rizol-raw ++++ ++ ++ ++++Rizol-raw ++++ ++ ++ ++++Ozone water ------- ------- ------- -------Ozone water ------- ------- ------- -------

2. Agar dilution test2. Agar dilution testPathogen Candida Aspergillus Aerobes AnaerobesPathogen Candida Aspergillus Aerobes AnaerobesRizol-concentr.Rizol-concentr.1,25 %1,25 % ++ -------------- ++ + +2,50 %2,50 % ++++ -------------- ++ ++ ++5,00 %5,00 % ++++++++ ++ ++++ +++ +++10,0 %10,0 % ++++++++ ++++ ++++ ++++ ++++

symbols:symbols: ------ no inhibition ------ no inhibition ++ minimal inhibitionminimal inhibition

++++ moderate inhibitionmoderate inhibition ++++++ good inhibitiongood inhibition ++++++++ very good inhibitionvery good inhibition

3. Decreasing the pathogen count3. Decreasing the pathogen count Hydrogenperoxide HHydrogenperoxide H22OO22 Ozon O Ozon O33

H-O-O-H H-O-O-H O-O-O O-O-OEndoperoxides in plants:Endoperoxides in plants:

3. Decreasing the pathogen count:3. Decreasing the pathogen count: Trioxolan (rizol ingredient): comparisons with endoperoxidesTrioxolan (rizol ingredient): comparisons with endoperoxides

3. Decreasing the pathogen count3. Decreasing the pathogen count

3. Decreasing the pathogen count3. Decreasing the pathogen count The Steidl/Carstens studiesThe Steidl/Carstens studies

Biological effectsBiological effects The ozonides transfer oxygen and change the environment The ozonides transfer oxygen and change the environment

in which anaerobic pathogenic germs live, making it aerobic in which anaerobic pathogenic germs live, making it aerobic This prevents anaerobic germs, such as Clostridia, from This prevents anaerobic germs, such as Clostridia, from

multiplyingmultiplying The oil is surface-active and, with its active substances, The oil is surface-active and, with its active substances,

moistens the intestinal mucous membrane where nests of moistens the intestinal mucous membrane where nests of fungi fungi and bacteria and parasites might be locatedand bacteria and parasites might be located

The rizol constituents have been found intracellularly and in The rizol constituents have been found intracellularly and in the the matrix (indicating anti-microbial activity both intra-and matrix (indicating anti-microbial activity both intra-and extracellularly ) extracellularly )

Cell toxicology studies: Cell toxicology studies: mitochondria are not damaged, mitochondria are not damaged, OECD test for mutagenicity produced the result: not OECD test for mutagenicity produced the result: not

mutagenic. mutagenic. Normal human cells are guided into apoptosis (beneficial Normal human cells are guided into apoptosis (beneficial and and

genetically pre-programmed cell death)genetically pre-programmed cell death) previously damaged and tumour cells are destroyedpreviously damaged and tumour cells are destroyed no adverse pharmacological effects were found in numerous no adverse pharmacological effects were found in numerous

cell culture tests cell culture tests

4. Immunemodulation4. Immunemodulation

1.1. Use the CD 57 test (Labcorp – Stricker panel) to monitor immune statusUse the CD 57 test (Labcorp – Stricker panel) to monitor immune status

2.2. Enderlein remedies: treat immune responses to mold: Nigersan, Notakehl, Enderlein remedies: treat immune responses to mold: Nigersan, Notakehl, Mucukehl, Fortakehl, Pefrakehl General Immune modulation: Utilin, Mucukehl, Fortakehl, Pefrakehl General Immune modulation: Utilin, Utilin -S, Latensin, RecarcinUtilin -S, Latensin, Recarcin

3.3. Auto-hemotherapy or auto-urine therapy (2 ml biw)Auto-hemotherapy or auto-urine therapy (2 ml biw)

4.4. Buhner herbs (Quintessence from BioPure) 8-10 dropperfull in 1 liter waterBuhner herbs (Quintessence from BioPure) 8-10 dropperfull in 1 liter water

5.5. Allergie-Immun saliva based drops (Germany)Allergie-Immun saliva based drops (Germany)

6.6. Klinghardt H-7 homeopathics made from saliva, urine and stoolKlinghardt H-7 homeopathics made from saliva, urine and stool

7.7. Adjunctive physics based immune modulation tools(BioTools):Adjunctive physics based immune modulation tools(BioTools):• KMT frequency-based biofield treatment (anti-microbial CDs)KMT frequency-based biofield treatment (anti-microbial CDs)• Health Light super LED treatment of focal areasHealth Light super LED treatment of focal areas• Valkion: singlet oxygen energy delivery via inhaled air or drinking water Valkion: singlet oxygen energy delivery via inhaled air or drinking water • Photon Wave or Laser immune modulationPhoton Wave or Laser immune modulation

Medical drugsMedical drugs

Occasionally the use of medicalOccasionally the use of medical antimicrobials is beneficial in addition toantimicrobials is beneficial in addition to this program (ILADS recommendations)this program (ILADS recommendations)

Top of the list: Top of the list:

• anti-virals (Valtrex and Valcyte) anti-virals (Valtrex and Valcyte) • anti-fungals (itra- and voriconazole)anti-fungals (itra- and voriconazole)• anti-parasitics (Alinia and Biltricide)anti-parasitics (Alinia and Biltricide)• antibiotics (with above program, antibiotics (with above program,

minocycline, and anti-Malarials work again!)minocycline, and anti-Malarials work again!)

contactcontact

Dietrich Klinghardt MD, PhDDietrich Klinghardt MD, PhD

Office (Kirkland/Seattle): 425 823 8818Office (Kirkland/Seattle): 425 823 8818

www.klinghardt.orgwww.klinghardt.org