1
1070 Scientific, especially medical scientific, departments often carry one or two men regarded as " passengers " by their colleagues because they do no research or at least publish none. I strongly suspect that a proportion of these men have got into academic medicine not realising in the first place how far away it would take them from the humanitarian side of their profession. They are inactive in research because of a reluctance to specialise beyond a certain point which their general medical training disposes them to find the limit com- patible with a humanitarian, a7opposed to a scientific, outlook. Only in their teaching can they feel sure that they are doing something of definite value to society. The more widespread teaching of general medicine to undergraduates would not only benefit the latter but might also provide an outlet for doctors with an urge to teach without having to make a pretence at embracing some specialty. Holbeach, Lincolnshire. A. J. RICHARDS. THEORY OF CEREBRAL LOCALISATION W R,-I agree with Dr. Jefferson’s thesis (April 28) that the results of hemispherectomy call only for a renewal of attention to already established, though recently unemphasised, clinical and experimental observa- tions, rather than for any radical revision of theories of cerebral localisation ; but the effects do not seem to me to argue against Jackson’s view that destructive lesions cause negative symptoms. The clinical and electrical evidence suggests that the damaged hemisphere as a whole constitutes in Jacksonian terms a " discharging " quite as much as a " destructive " lesion. The results of removal are essentially negative -namely, a reduction of abnormal discharge. The beneficial effect on the remaining cerebral economy reflects the extent of the abnormal discharge removed. Although, apart from the visual sphere, the evidence does not as yet reveal any clear loss of " normal func- tion, I would hazard a guess that further study will enable us to see something of that too : though it may weigh very light in the balance of over-all benefit to the patient. Oxford. C. W. M. WHITTY. SIZE OF MEDICAL SCHOOLS AND HOSPITALS SiR,-I was interested in the letter from " Calculus in your issue of April 21. I took my 1st M.B. work at Toronto University, in a class of 150 students. Since then I have been at the Middlesex Hospital in London, where classes have averaged 45. At Toronto two shifts of 75 students were formed for practical classes. These were each attended by the respective professors, assisted by three demonstrators. In the physics and chemistry departments practical books were handed in for examination once weekly, and were verbally corrected at the next class. In biology the last fifteen minutes of each three-hour session was spent in a more or less informal viva from professor or demon- strator (working in rotation through the whole class), for which marks were assigned, these marks being con- sidered when assessing the students’ examination results in the first-year final examinations. Furthermore the chemistry professor within the first six weeks of the autumn term could accurately fit name to face of all of the 150 students. This was achieved by assigning to each student a numbered seat in the lecture-theatre, and the professor having on his desk a plan of the seats with the students’ names entered on it. Also, if any student missed a lecture in a subsequent practical period the professor saw to it that that student understood the substance of the lecture that he had missed. In physiology I had the good fortune to be taught by Prof. Samson Wright and Dr. (now Professor) D. Slome. Physiology, as taught by them, was not isolated studies of nervous system, circulation, digestion, &e. Each field was discussed in relation to the others; and through all, by a rapid-fire question-and-answer technique, we were taught to think rationally and for ourselves. These experiences lead me to conclude that the complex graphs and statistics mentioned by " Calculus," of which I have even less understanding than he, are not the only factors in deciding how a big medical school ought to be. Good teachers are essential, and come before problems of capital outlay, running-costs, and so on. It is not true -that a personal relationship cannot be established in large classes or that two people cannot adequately teach physiology, when first-class teachers willing to work at their job, can be found. London, N.W.3 ROY MOTTRAM. HYPERCALCÆMIC URÆMIA WITH NEPHROCALCINOSIS SIR,-The interesting case recorded by Dr. Fulton and Dr. Paget (April 21) is surpassed by one described by Albright.l This was of a man of 50 who had a single metastasis of the right ilium and sacrum from a " hyper- nephroma " of the kidney, associated with hypercalcaemia, and hypercalcuria. The interesting part of the story is that the serum and urinary calcium values went back to normal when the metastasis was irradiated, only ta rise again when the condition relapsed. Dr. Fulton and Dr. Paget suggest that " the syndrome only develops in cases in which the bony secondaries are of sufficiently wide distribution or long duration." This cannot be, as in Albright’s case they were not widely distributed; and their comparatively rapid response to irradiation with subsequent relapse shows that long duration is not important. It is probably all a question of how quickly bone is being destroyed. Department of Pathology, University of Bristol. OLIVER C. LLOYD. FOOD AND ENERGY biR,—it is now some centuries since the scientic method of observation and experiment replaced authori- tarianism, but I sometimes wonder whether the replace- ment was complete or whether the wheel is turning full circle. For we continually meet with statements made, or uncritically quoted, by men of authority which, when subjected to scientific criticism, turn out to be no more than expressions of opinion. When such statements of a technical nature are made by people not skilled in the relevant branch of technology there is at least the excuse of ignorance, but it ill becomes the expert to lend his authority by quotation which implies tacit approval. In his letter of March 10 Dr. Franklin Bicknell, possibly with caution but certainly with subtle emphasis, quoted without comment from the report of the Productivity Team on Rigid Boxes and Cartons to the effect that diet plays an important part in enabling the American worker to work faster and to sustain the effort. Dr. Bicknell, with an accuracy which is unusual in such quotations, gave the entire relevant section of the report. There is nothing in the report to substantiate this surprising claim, which turns out to be a statement of opinion, if not of prejudice, and not of fact. The only piece of what might purport to be evidence is that members of the productivity team were able to work all day without fatigue. While the layman might be excused for putting this down to the first cause that comes to mind-namely, food-Dr. Bicknell must surely agree that change of environment, change of working conditions, intellectual stimulus, new interests, to mention but a few, might equally be responsible for the absence of fatigue. London, W.13. A. E. BENDER. 1. Albright, F., Reifenstein, E. C. Parathyroid Glands and Metabolic Bone Disease. London, 1948.

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Page 1: THEORY OF CEREBRAL LOCALISATION

1070

Scientific, especially medical scientific, departmentsoften carry one or two men regarded as

"

passengers "

by their colleagues because they do no research or atleast publish none. I strongly suspect that a proportionof these men have got into academic medicine not

realising in the first place how far away it would takethem from the humanitarian side of their profession.They are inactive in research because of a reluctance tospecialise beyond a certain point which their generalmedical training disposes them to find the limit com-patible with a humanitarian, a7opposed to a scientific,outlook. Only in their teaching can they feel sure thatthey are doing something of definite value to society.The more widespread teaching of general medicine to

undergraduates would not only benefit the latter but

might also provide an outlet for doctors with an urge toteach without having to make a pretence at embracingsome specialty.

Holbeach, Lincolnshire. A. J. RICHARDS.

THEORY OF CEREBRAL LOCALISATION

W R,-I agree with Dr. Jefferson’s thesis (April 28)that the results of hemispherectomy call only for a

renewal of attention to already established, thoughrecently unemphasised, clinical and experimental observa-tions, rather than for any radical revision of theories ofcerebral localisation ; but the effects do not seem to meto argue against Jackson’s view that destructive lesionscause negative symptoms.The clinical and electrical evidence suggests that the

damaged hemisphere as a whole constitutes in Jacksonianterms a " discharging " quite as much as a

" destructive "lesion. The results of removal are essentially negative-namely, a reduction of abnormal discharge. Thebeneficial effect on the remaining cerebral economyreflects the extent of the abnormal discharge removed.Although, apart from the visual sphere, the evidencedoes not as yet reveal any clear loss of

" normal func-tion, I would hazard a guess that further study willenable us to see something of that too : though it mayweigh very light in the balance of over-all benefit to thepatient.

Oxford. C. W. M. WHITTY.

SIZE OF MEDICAL SCHOOLS AND HOSPITALS

SiR,-I was interested in the letter from " Calculusin your issue of April 21.

I took my 1st M.B. work at Toronto University, in aclass of 150 students. Since then I have been at theMiddlesex Hospital in London, where classes have

averaged 45.At Toronto two shifts of 75 students were formed for

practical classes. These were each attended by therespective professors, assisted by three demonstrators.In the physics and chemistry departments practicalbooks were handed in for examination once weekly, andwere verbally corrected at the next class. In biology thelast fifteen minutes of each three-hour session was spentin a more or less informal viva from professor or demon-strator (working in rotation through the whole class),for which marks were assigned, these marks being con-sidered when assessing the students’ examination resultsin the first-year final examinations. Furthermore the

chemistry professor within the first six weeks of theautumn term could accurately fit name to face of all ofthe 150 students. This was achieved by assigning toeach student a numbered seat in the lecture-theatre,and the professor having on his desk a plan of the seatswith the students’ names entered on it. Also, if anystudent missed a lecture in a subsequent practical periodthe professor saw to it that that student understoodthe substance of the lecture that he had missed.

In physiology I had the good fortune to be taughtby Prof. Samson Wright and Dr. (now Professor) D.

Slome. Physiology, as taught by them, was not isolatedstudies of nervous system, circulation, digestion, &e.Each field was discussed in relation to the others; andthrough all, by a rapid-fire question-and-answer technique,we were taught to think rationally and for ourselves.

These experiences lead me to conclude that the complexgraphs and statistics mentioned by

" Calculus," of whichI have even less understanding than he, are not the onlyfactors in deciding how a big medical school ought to be.Good teachers are essential, and come before problemsof capital outlay, running-costs, and so on. It is nottrue -that a personal relationship cannot be establishedin large classes or that two people cannot adequatelyteach physiology, when first-class teachers willing towork at their job, can be found.London, N.W.3 ROY MOTTRAM.

HYPERCALCÆMIC URÆMIA WITHNEPHROCALCINOSIS

SIR,-The interesting case recorded by Dr. Fultonand Dr. Paget (April 21) is surpassed by one describedby Albright.l This was of a man of 50 who had a singlemetastasis of the right ilium and sacrum from a " hyper-nephroma " of the kidney, associated with hypercalcaemia,and hypercalcuria. The interesting part of the story isthat the serum and urinary calcium values went backto normal when the metastasis was irradiated, only tarise again when the condition relapsed.

Dr. Fulton and Dr. Paget suggest that " the syndromeonly develops in cases in which the bony secondaries areof sufficiently wide distribution or long duration." Thiscannot be, as in Albright’s case they were not widelydistributed; and their comparatively rapid responseto irradiation with subsequent relapse shows that longduration is not important. It is probably all a questionof how quickly bone is being destroyed.

Department of Pathology,University of Bristol. OLIVER C. LLOYD.

FOOD AND ENERGY

biR,—it is now some centuries since the scientic

method of observation and experiment replaced authori-tarianism, but I sometimes wonder whether the replace-ment was complete or whether the wheel is turning fullcircle. For we continually meet with statements made,or uncritically quoted, by men of authority which, whensubjected to scientific criticism, turn out to be no morethan expressions of opinion. When such statements ofa technical nature are made by people not skilled in therelevant branch of technology there is at least the excuseof ignorance, but it ill becomes the expert to lend hisauthority by quotation which implies tacit approval.

In his letter of March 10 Dr. Franklin Bicknell, possiblywith caution but certainly with subtle emphasis, quotedwithout comment from the report of the ProductivityTeam on Rigid Boxes and Cartons to the effect that dietplays an important part in enabling the American workerto work faster and to sustain the effort. Dr. Bicknell,with an accuracy which is unusual in such quotations,gave the entire relevant section of the report. Thereis nothing in the report to substantiate this surprisingclaim, which turns out to be a statement of opinion, ifnot of prejudice, and not of fact.The only piece of what might purport to be evidence

is that members of the productivity team were able towork all day without fatigue. While the layman mightbe excused for putting this down to the first cause

that comes to mind-namely, food-Dr. Bicknell mustsurely agree that change of environment, change ofworking conditions, intellectual stimulus, new interests,to mention but a few, might equally be responsible forthe absence of fatigue.London, W.13. A. E. BENDER.

1. Albright, F., Reifenstein, E. C. Parathyroid Glands and MetabolicBone Disease. London, 1948.