Homeostasis & Thermoregulation

Audric Albertus ReinardIustitia Septuaginta Samben Adji Karlita ShaviraFerdie Sundjoyo ShianitaJimmy Surya AdiwenaKharis Ikamuda Holidi

Tutorial dr. VictorFK UPH 2012

Homeostasis

Sistem Tubuh

Homeostasis

Sel

Mempertahankan

Pentinguntukkelangsunganhidup

Membentuk

Some stimulus disrupts

homeostasis by

Controlled condition that is

monitored by

ReceptorsThat send

Control centerThat receives the input and

provides

EffectorsThat bring about

a change or

Increasing or decreasing a

Response that alters the controlled condition

Nerve impulses or chemical signals to a

Input

Output

Nerve impulses or

chemical signals to

There is a return to

homeostasis when the response bring the controlled condition back to normal

Response in Homeostasi

s

Temperature Regulation

Skin Temperature

Heat loss and heat gain

Hypothalamus

Core Temperature

- -

Thermoregulation

Change in environmental temperature

Change in core body

temperature

Peripheral thermorecept

ors

Central thermorecept

ors

Hypothalamic thermoregulatory center

Symphathetic cholinergic

neurons

Sweat glands

Sweat secretion

Heat lost through

evaporative cooling

Cutaneous blood

vessels

Vasodilatation

Heat lost to

environment

Symphathetic adrenergic

neurons

Symphathetic motor neurons

Cutaneous blood

vesselsVasoconstricti

on

Heat conserved

Brown Fat(Baby)

Nonshivering

thermogenesis

Skeletal muscles

Shivering thermogene

sis

Metabolic heat

production

Response to decrease

temperature

Response to increase

temperature

Antigens recognized as foreign

- Infectious- Autoimmune- - neoplastic

Elevation of hypothalamic

temperature set point

Increased heat gain, reduced heat

loss- Vasoconstriction

- Shivering- Behaviour

Elevation of hypothalamic

temperature to a new set point:

fever

Activated immune response cells- Leukocytes

- Mesangial cells- Vascular endothelial cells

- astrocytes

Production of interleukins 1 and 6

Increased prostaglandin E2 synthesis in the hypothalamus

FEVER

MECHANISM

Fever Temparation

HEAT

STROKE

Thank You For Your Attention