CURRICULUM VITAE THOMAS LOWELL PAZDERNIK Date of Birth: January 3, 1943 Place of Birth: Detroit Lakes, Minnesota Marital Status: Married, spouse: Betty C. Children: Lisa Ann; August 9, 1970 Nancy Lea; September 7, 1974 Addresses: Office: 4083 KLSIC Department of Pharmacology, Toxicology & Therapeutics University of Kansas Medical Center

Kansas City, Kansas 66103 (913) 588-7504/7140 Fax: (913) 588-7501 e-mail:tpazdern@kumc.edu Updated: October 2010 Education:

Undergraduate, College of St. Thomas, St. Paul, Minnesota, 1961-1963

B.S. in Pharmacy, School of Pharmacology, University of Minnesota, Minneapolis, Minnesota, 1963-1967

Ph.D. in Medicinal Chemistry, Department of Medicinal Chemistry, School of

Pharmacy, University of Kansas, Lawrence, Kansas, 1967-1971 Mentor: Edward E. Smissman, Ph.D.

Thesis: The synthesis of semirigid and rigid analogs of β-methylamphetamine

Postdoctoral Research Associate, Department of Pharmacology, School of

Medicine, University of Kansas Medical Center, Kansas City, Kansas, 1971-1973.

Mentor: Edwin U. Uyeki, Ph.D. Training in immunopharmacology

Visiting Scientist, Department of Pharmacology, University of Helsinki, Helsinki,

Finland, March-September, 1976 Research in Neuropharmacology Professional Appointments: 1965-1967: Research Assistant, Department of Medicinal Chemistry, University of

Minnesota, Minneapolis, Minnesota 1967-1971: Laboratory Instructor, Department of Medicinal Chemistry, University of

Kansas, Lawrence, Kansas 1967-1971: Predoctoral Fellow, Department of Medicinal Chemistry, University of

Kansas, Lawrence, Kansas 1971-1973: Postdoctoral Fellow, Department of Pharmacology, University of Kansas

Medical Center, Kansas City, Kansas 1973-1977: Assistant Professor, Department of Pharmacology, University of Kansas

Medical Center, Kansas City, Kansas 1975- Associate Scientist, Mid-America Cancer Center 1976: Visiting Research Scientist, Department of Pharmacology, University of

Helsinki, Helsinki, Finland 1977-1984: Associate Professor, Department of Pharmacology, University of Kansas

Medical Center, Kansas City, Kansas 1983- Key Investigator, Ralph L. Smith Research Center, University of Kansas

Medical Center, Kansas City, Kansas 1984- Professor, Department of Pharmacology, Toxicology and Therapeutics,

University of Kansas Medical Center, Kansas City, Kansas 1986-1989: Associate Dean for Student Affairs, School of Medicine, University of

Kansas Medical Center, Kansas City, Kansas 1986- Professor Environmental Health Center, University of Kansas Medical

Center, Kansas City, Kansas 1991-1992 Acting Chairman, Department of Pharmacology, Toxicology &

Therapeutics, University of Kansas Medical Center, Kansas City, Kansas

Curriculum Vitae Thomas Lowell Pazdernik Page 3 1993- Director, Educational Activities, Department of Pharmacology, Toxicology

& Therapeutics 2007- Chancellor's Club Teaching Professor Awards: Mead Johnson Laboratories Grant for Undergraduate Research in Pharmacy N.D.E.A. Title IV Fellowship NIH Predoctoral Fellowship NIH Postdoctoral Fellowship NIH Career Development Award Best Nursing Educator, 1982 MSA Outstanding Educator, 1984-1985 Student-Faculty Relations Committee Appreciation Award, 1988 Student Voice, Honors in Education, 1989-1990 Student Voice, Excellence in Education, 1990-1991 Student Voice, Outstanding Educator, 1991-1992 Ruth Bohan Award, 1992 Department: Outstanding Department of the Year, 1991-1992 Course Director Department: Outstanding Department of the Year, 1993-1994 Course Director Graduation Marshall, 1994 Department: Outstanding Department of the Year, 1994-1995 Course Director Student Voice, Excellence in Education, 1994-1995 Department: Outstanding Department of the Year, 1995-1996 Course Director Student Voice, Excellence in Education, 1995- 1996 Chancellor’s Distinguished Teaching Award, 1997 Graduation Marshall, 1997 Student Voice, Excellence in Education, 1996-1997 Student Voice, Excellence in Education, 1997 - 1998 Student Voice, Excellence in Education, 1998 - 1999 Department: Outstanding Department of the Year, 1998-1999 Course Director Student Voice, Excellence in Education, 1999 - 2000 Graduation Marshall, 2000 Student Voice, Excellence in Education, 2000 -2001 Department: Outstanding Department of the Year, 2000 -2001 Course Director Student Voice, Excellence in Education, 2001 -2002

Curriculum Vitae Thomas Lowell Pazdernik Page 4 Department: Outstanding Department of the Year, 2001 -2002 Course Director Outstanding Educator Award, 2001-2002 Kemper Fellowship, 2002 Certificate of Excellence: Chair of Promotion & Tenure Committee (2000- 2002) Student Voice: Outstanding Second-year Educator. 2002-2003 Student Voice: Outstanding Second-year Discussion Group Leader, 2002-2003 Department: Outstanding Department of the Year, 2002 -2003 Course Director Graduation Marshall, 2003 Student Voice: Outstanding Second-year Educator. 2003-2004 Department: Outstanding Department of the Year, 2003 -2004 Course Director Graduation Marshall, 2004 Student Voice: Outstanding Second-year Lecturer. 2004-2005 Student Voice: Outstanding Second-year Discussion Group Leader, 2004-2005 Department: Outstanding Department of the Year, 2004 -2005 Course Director Student Voice: Outstanding Second-year Lecturer. 2005-2006 Student Voice: Outstanding Second-year Discussion Group Leader, 2005-2006 Department: Outstanding Department of the Year, 2005 -2006 Course Director Graduation Marshall, 2006 Student Voice: Excellence In Teaching 2006-2007 Student Voice: Department Best Course Overall Course Director Graduation Marshall, 2007 Chancellor's Club Teaching Professorship, 2007 Kemper Fellowship, 2007 Graduation Marshall, 2008 Student Voice: Outstanding Second Year Module 2008-2009 Module Director Student Voice Excellence in Teaching 2008-2009 Student Voice: Outstanding Second Year Module 2009-2010 Module Director Student Voice Excellence in Teaching 2009-2010 Professional Societies: Rho Chi Phi Lambda Upsilon American Chemical Society Sigma Xi

Curriculum Vitae Thomas Lowell Pazdernik Page 5 Tissue Culture Association American Society for Pharmacology and Experimental Therapeutics CATS Consortium International Society for Immunopharmacology American Association for the Advancement of Science Society of Toxicology Society of Neuroscience Central States Chapter, Society of Toxicology 1986-1988, Program Committee 1987-1988, Vice President 1989-1991, Councilor 1990-1991, Program Committee KUMC Sigma-Xi Chapter 1990-1991, President Elect 1991-1992, President International Association of Medical Science Educators (IAMSE) Delp Medical Student Society Assistant Editor: Journal Pharmacology and Experimental Therapeutics, 1997- 2003 Ad hoc Reviewer for the following Journals: Journal of Pharmacology and Experimental Therapeutics Fundamental and Applied Toxicology Toxicology and Applied Pharmacology Life Science Neurotoxicology European Journal of Pharmacology Pharmacology and Toxicology Neurosciences Journal Leukocyte Biology Journal Medicinal Chemistry Pediatric Research Brain Research Brain Research Protocols Toxicological Sciences Human and Experimental Toxicology Journal of Pharmacy and Pharmacology Chairman (Pharmacology Section) Doody’s Book Reviews; 2002 – Pharmacology chairperson for the NBPME Part I Basic Science Examination; 2006 -

Curriculum Vitae Thomas Lowell Pazdernik Page 6 Grants: Grants, Awards Amount Year(s) Support 1. NIH: Predoctoral Fellowship (GM 49025) salary 1970-1971 2. NIH: Postdoctoral Fellowship (GM 50743) salary 1971-1973 3. Pharmaceutical Manufacturers Association $ 5,000 1973-1974 Grant (P.I.) 4. NIH: Research Career Development Award salary 1975-1980 (CA-14386) 5. NIH: Toxicity of antitumor drugs (CA-14386) $ 93,000 1973-1976 6. NIH: Toxicity of benzene and related compounds $ 75,000 1975-1978 (ES-01004) 7. NIH: Aplastic anemia and chloramphenicol $ 65,000 1976-1978 (CA-21667)

8. Biomedical Research Support Grant: $ 3,000 1978-1979

Co-investigator with Dr. Silvergladt 9. U.S. Army Contract No. DAMD17-78-C-8039 $ 354,000 1980-1983 Co-investigator with Dr. Samson, Dr. Nelson 10. Biomedical Research Support Grant (P.I.) $ 3,000 1980 11. March of Dimes (P.I.) $ 36,000 1980-1982 12. NIH: Comparative trial of propranolol and $ 242,000 1981-1984

amitriptyline for prophylaxis of migraine (NS 16662); Co-investigator with Dr. Ziegler 13. U.S. Army Contract No. DAMD17-83-C-3242 $ 636,000 1983-1986 Co-investigator with Dr. Samson, Dr. Nelson

Curriculum Vitae Thomas Lowell Pazdernik Page 7 14. U.S. Army Grant No. DAMD17-86-G-6038 $1,000,000 1986-1990 Co-PI with Dr. Samson, Dr. Michaelis 15. U.S. Army Contract No. DAMD17-90-C-0041 $ 392,962 1990-1992

P.I.

16. NIH 2-P30 HD02528-251A: Program for $ 98,312 1991-1993 a research center in mental retardation Stephen Schroeder, PI — New Program Project: Reductase oxygen species in neuronal tissue (Co-PI) 17. NIH-I-P30-AG10182: Alzheimer disease a $ 20,000 1992-1993 center core grant William Koller, PI Free radical enzyme damage: An Alzheimer disease study. Pilot Study 18. USAMRD DAMD 17-94-C 4045 $737, 674 1994-1998

P.I. Mechanism of chemically induced brain damages: are free radical a common effector linkage

19. NIH 1-P20-RR10256-01 $72,084 (NIH) 1994-1996 The Kansas IDEA $107,586 (State) P.I. $179,670 (Total) 20. DAMD AASERT DAAH04-95-1-0217 $ 88,453 1995-1998 P.I. Free radicals in chemical induced brain damage Departmental Duties: 1. Director of nursing pharmacology course (1973-1985) -- lectures in general principles of pharmacology, and chemotherapy 2. Director of Pharmacology graduate program (1978-1983) 3. Chairman of general principles unit of medical pharmacology course (1977-present) 4. Lectures in chemotherapy of medical pharmacology course (1975-present) 5. Chairman of immunopharmacology core graduate course (given every other year) 6. Lectured in chemical and cellular pharmacology graduate course 7. Presented advance topic course in immunopharmacology 8. Headed departmental seminar series (1977-1980) 9. Participation and development of materials for CATS Consortium (1973 to 1991)

Curriculum Vitae Thomas Lowell Pazdernik Page 8 10. Member of the Ph.D. Toxicology Planning Committee 11. Departmental Promotion and Tenure Committee (1989- 1992) 12. Member of Pharmacology Graduate Committee (1989-1993) 13. Authored Department LCME Report (1989, 1996) 14. Chairman of Neuro/Immunopharmacology Graduate Course (New Course 1991) 15. Director, Pharmacology/Toxicology Graduate Programs (1989-1994) 16. Course Director, Medical Pharmacology Course (1991-present) 17. New Faculty Search Committee (1993-1995) 18. Department Space Committee 19. Block leader of Block I; Medical Pharmacology (1993-present) 20. Small group discussion facilitator of Block I; Medical Pharmacology (1993-present) 21. Unit Chairman of Toxicology section; Medical Pharmacology (1999-present) 22. Unit chairman of Immuno/hematopharmacology section; Medical Pharmacology

(2000-present) 23. Lectures in Various Graduate Courses each year 24. Department Graduate Committee (1998 - 2001) Chairman (2000 - 2001) 25. Small group discussion facilitator of Block III; Medical Pharmacology (1999- present) 26. Graduate School Graduate Counsel (2000 - 2001) 27. Department Promotion & Tenure Committee (1999 - ) 28. Small group discussion facilitator of Block II; Medical Pharmacology (2002 - present) 29. Department Graduate Committee (2002 - ) 30. Department Faculty Search Committee (2002- ) 31. Course Director of Essentials in Pharmacology (PHCL 880); Graduate course (2004, 2006, 2008) 32. Facilitator of all small group discussions in PHCL 880 (2006, 2008) 33. Redesigned the PHCL 700 Series (PHCL 761, 762, 763, 764, 765, 766, & 767) for Nurse Anesthesia Students; about 10 hours of review & consultation for each course) [2006] 34. Redesigned the PHCL 700 Series (PHCL 761, 762, & 764) for Audiology Doctoral Students; about 10 hours of review & consultation for each course) [2006] 35. PHCL 761 for Doctoral Nursing Practioneer students; 8 hours every semester Thesis Committees of Master Students: Dan Wierda, Pharmacology (chairman) Jeanne Curry, Nursing Lorena Taylor, Nursing Dave Eigenberg, Pharmacology Jim Barter, Pharmacology Moshe Garty, Pharmacology Willis Burton, Pharmacology (chairman)

Curriculum Vitae Thomas Lowell Pazdernik Page 9 Fred Lowry, Pharmacology (chairman) Judith Radhol, Nursing Phillip Miller, Pharmacology Kim Brydon, Anatomy Cheryl Ratliff, Nursing Jane Rachel, Special Studies Robin Pearce, Toxicology Qiu Xie, Pharmacology (Chairman) Ida Howell, Toxicology Neda Leonard, Toxicology Lesley Rausch-Derra, Toxicology Janean Hanson, Pharmacology Michael Berringer, Toxicology Jeremy Johnson, Toxicology Alphonse Mendy, Toxicology Dissertation Committees of Doctoral Students: John Gordon, Pharmacology Dave Eaton, Pharmacology Dan Wierda, Pharmacology (chairman) King Wong, Pharmacology Lou Cantilena, Pharmacology Mike Elwell, Pathology Dave Eigenberg, Pharmacology (co-advisor) Peggy Brown, Special Studies (Immunohematology) Lyle Sinor, Special Studies Jim Chastain, Pharmacology (chairman) Peter Goering, Pharmacology Bob Dudley, Pharmacology John Wade, Toxicology (chairman) John Olson, Anatomy Russ Dills, Toxicology Lois Lehman, Toxicology Kai Savolainen, Toxicology (chairman) Mike Arlotto, Toxicology Roberto Mangoo-Karim, Pharmacology Earl Morgan, Toxicology Catherine Dorian, Toxicology Brian Gemzik, Toxicology Matthew Layton, Pharmacology (chairman) Maria Romanas, Pharmacology (chairman) Jie Liu, Toxicology Larry Davidow, Pharmacology

Curriculum Vitae Thomas Lowell Pazdernik Page 10 Clarissa Haugsness, Pharmacology Peter Bullock, Toxicology Tony Zink, Pharmacology Lan Liu, Toxicology Xuelin Li, Toxicology Fan Fang, Toxicology Mitch Emerson, Pharmacology (chairman) Ulrich Schmitt (University of Magdeburg) Jim Boles, Toxicology Amy, Mize, Pharmacology Eric Harstad, Toxicology Janean Hanson, Toxicology Melissa Jones, Anatomy Ning Li, Toxicology Claire Croutch, Toxicology John Weroha, Toxicology Mindy Shelby, Toxicology Amy Allen, Pharmacology Vanja Duric, Pharmacology Toni Richards, Pharmacology Christen Fried, Toxicology Jagan Muppidi, Toxicology Jerri Rook, Pharmacology Beth Hontz, Pharmacology Andy Rayla, Pharmacology Pungli Bu, Toxicology Peter Ojong, Toxicology Sharry Shelton, Pharmacology Scott Reismann (ADR) Hyoungwoo Bai, Pharmacology Coleen Flynn, Pharmacology Nick Stucky, Pharmacology Pan Wang (ADR) Kristen Russell, Pharmacology Stephanie Bishop, Pharmacology Mischelle, Healy, Pharmaclogy Medical Student Mentor (Delp Society) [1999 to present]: Mentor to 5 to 6 students per year Some Recent Students: Amber Mounday

Curriculum Vitae Thomas Lowell Pazdernik Page 11 Holly Seybold Rebecca Weller Denise Gentles Hamid Malik Aldon Corle Troy Holdman Angela Holdman Jon Gertken Jeremy Kirchoff Karra Jones My Luu Jennifer Fink Courtney West Gustaf Van Acher Michelle Healy Mary Pham Marta Lasater Medical Center Activities: 1. Member of Mid-America Cancer Center 2. Member of the Developmental Therapeutics Branch of the Mid-America Cancer

Center 3. Member of the immunology seminar group 4. Member of the immunology Journal club 5. Lectures in interdependent immunology graduate course 6. Participation in independent pharmacology course for University of Kansas

graduate students 7. Member of the Graduate Committee (1978-1983; 1990; 1992-1994) 8. Member of the Graduate Council (1978-1983; 1990, 1992-1994) 9. Member of the Graduate Student Fellowship Committee (1980-1983) 10. Member of the Graduate School Long-Range Planning Committee (1980-1983) 11. Drug analysis for the medical center and community 12. Member of KUMC Peer Grant Review 13. Graduate School Special Studies Program Committee 13. Graduate Scholarships, Fellowships and Awards Committee (1980-1983) 15. Basic Science Faculty Advisor to Medical Students 16. Faculty Affiliates Program for Minority Graduate Student Recruitment 17. Interviews for Medical Applicants (1982-1983) 18. Search Committee for Associate Dean of Research (1982) 19. Planning Committee for Interdepartmental Selectives (1983) 20. University of Kansas Cancer Center--Basic Science Task Force (1983) 21. Chairman of Interdepartmental Selectives Program (1984-1986) 22. Search Committee for Dean of Medical School (1985)

Curriculum Vitae Thomas Lowell Pazdernik Page 12 23. LCME Task Force (1985) 24. Academic-Student Promotions Committee (1985) 25. Academic Committee, Ex officio, 1986-1989 26. Curriculum Committee, Ex officio, 1986-1989 27. Curriculum task force, 1986-1989 28. Committee on tuition Adjustment (1986) 29. Financial Aid Advisor Committee (1986-1989) 30. Kansas Medical Scholarship Advisory Committee (1986-1989) 31. Search Committee for Dean of Nursing School (1987) 32. Biological Science Series, Departmental Representative (1989-1997) 33. MRRC Advisor Committee (1990-1999) 34. Election Committee (1990) 35. National Boards CBX System, Chairman of Committee (1989-1991) 36. Committee on Governance (1991) 37. Chairman Review Committee, Biochemistry (1992-1993) 38. Environmental Health Toxicology Training Grant Advisor Committee 39. M.D./Ph.D. Advisor Committee (1992-1994) 40. M.D./Ph.D. Scholarship Committee (1992-1994) 41. Associate Dean for Academic Affairs Search Committee (1993) 42. Senior Associate Dean for Academic Affairs Search Committee (1994) 43. MRRC Space Committee (1994 -1999) 44. Neuroscience Course Committee (1994 -1999) 45. Faculty Council, Vice Chairman (1994 -1995) 46. Executive Committee (1994 -1995) 47. Attend Associate Deans Meetings 48. Academic Committee (1994 -1997) 49. Special Programs Committee (1994 -1997) 50. IDEA Research Committee, Director (1994 -1997) 51. Cell Biology Core Course Committee (1995-1996) 52. Admissions Panel, 1996 53. Lectures in Neuroscience Course (1997- present) 54. Year 2 Curriculum Planning Committee (1997-1999) 55. Faculty Development Committee (1997-1999) 56. Mock Interviews for Health Careers Pathway Program (1994- present) 57. Productivity Planning Advisory Committee (PPAC): Educational Task Force (1997-1999) 58. Strategic Planning Initative: Education Task Force (1998 -2000) 59. Medical School Admissions Interviews (1997 - 1999) 60. Medical School Promotion & Tenure Committe (1999 -2002) Chairman (2000 - 2002) 61. Medical School Academic Committee (1999 - ) 62. Medical School Admissions Committee (1999 - ) 63. Bohan Teaching Award Committee (1999) 64. Executive Committee (2000 - 2002)

Curriculum Vitae Thomas Lowell Pazdernik Page 13 65. Faculty Council (2000 - 2002) 66. Election Committee (2000- 2003) 67. Policy Concerns Committee (2000 - 2003) 68. Chairman of Review Committee to review Dr. Tony David; Director of Laboratory Animal Resources (2000) 69. Laboratory Animal Resources Director Search Committee (2000 -2001) 70. Year 1 -2 Education Committee (1998 - ) 71. Ad hoc Committee on Academic Intervention (2000 - 2001) 72. Ad hoc Committee to write the Clinical Scholars track (2000 -2001) 73. Chair, Year 1 and 2 Oversight Committee (2002-2004) 74. KUMC Training Program Committee (2001-2007) 74. Handbook Revision Committee (2002-2005) 75. Student Research Fourm: Judge (1990 - present) 76. Medical Education Initiative: Student Evaluation and Testing & Technology in Education Taskforce (2003-2004) 77. Medical Education Initiative: Practical (Short Term Planning) Taskforce (2003-2004) 78. P & T Taskforce Committee (2004) 79. Executive Committee (2004 - 2005) 80. Faculty Council (2004 - 2005) 81. Vice-Chair Faculty Council (2004 - 2005) 82. LCME Institutional Setting: Academic Environment & Research Committee (2004 -2005) 82. LCME Educational Program: Teaching & Evaluation Committee (2004 -2005) 83. 2005 Kemper Fellowships Selection Committee 84. New Curriculum Assessment and Evaluation Committee (2005) 85. Election Committee (2006 - 2009) 86. 2006 Kemper Fellowships Selection Committee 87. 2006 -2007 Pew Fellowship application Review 88. 2005 Kemper Fellowships Selection Committee 89. Nurse Anesthesia Curriculum Committee (2006 – present) Educational Materials Prepared: Authored or co-authored 70 CAI programs Authored Nursing Pharmacology Synopsis, Editions 1 and 2 Authored General Principles Section of Medical Pharmacology Syllabus (1983, 1984, 1986, 1987, 1989, 1991) Developed a nursing pharmacology question bank (ca. 5000 questions) Mosby ACE The Boards: Pharmacology, Co-editor (1994-1995) PCPE Computer Initiative (1995- 1999) WebCAI and Pharmacology Study Objectives (1996-) Rapid Review of Pharmacology, Co-author (2003) Developed 550 clinical vignette-type questions with feedback for Elsevier’s USMLE Steps 123 (2005)

Curriculum Vitae Thomas Lowell Pazdernik Page 14 Rapid Review of Pharmacology; Co-author (2006) Nurse Anesthesia Pharmacology Course, Learning Objectives, Electronic Syllabus, & 150 questions/ unit (1050 total) for: PHCL 761 General Principles PHCL 762 ANS Pharmacology PHCL 763 CVR Pharmacology PHCL 764 CNS Pharmacology PHCL 765 Chemotherapy PHCL 766 Blood-endocrine Pharmacology PHCL 767 Toxicology Development of Pharmacology Web modules to support the new curriculum Module Director: Consolidation & Integration; new curriculum Doctoral Audiology Pharmacology Course, Learning Objectives, Electronic Syllabus for: PHCL 761 General Principles PHCL 762 ANS Pharmacology PHCL 764 CNS Pharmacology Nurse Anesthesia Pharmacology Course (all revised 2009), Learning Objectives, Electronic Syllabus, & 200 questions/ unit (1200 total) for: PHCL 761 General Principles PHCL 762 ANS Pharmacology PHCL 763 CVR Pharmacology PHCL 764 CNS Pharmacology PHCL 765 Chemotherapy PHCL 766 Blood-endocrine Pharmacology Rapid Review of Pharmacology; Co-author (In Press) Seminars, Lectures, Meetings: 1972 Presented a 3-credit hour graduate course in the Department of Medicinal

Chemistry, University of Kansas, Lawrence 1974 Participated in Drug Abuse Conference, Topeka, KS 1974 Ad Hoc member of NIH project site visit, Carl M. Pearson, UCLA 1974 Mid-America Cancer Center, MRI 1974 Midwest Tissue Culture Association, Kansas City 1975 Participated in Immunopharmacology Symposium, Helsinki, Finland 1976 Lectured in graduate course, University of Helsinki 1976 Seminar, Department of Pharmacology, University of Helsinki 1976 Seminar, Turku University, Turku, Finland 1976 Seminar, Department of Microbiology, University of Helsinki 1977 Seminar, Department of Medicinal Chemistry, University of Kansas

Curriculum Vitae Thomas Lowell Pazdernik Page 15 1979 Sigma Xi 1979 Participated in CATS Peer Review Committee, Lake Tahoe 1980 Participated in ADCIS meeting, Washington, D.C. 1980 Lectured in Mid-America Toxicology Course 1981 Lectured Johnson County LPN Association 1981 Lectured in Mid-America Toxicology Course 1981 Participated in the Service Conference on Defense Against Chemical Agents,

Reston, Virginia 1982 Lectured in Mid-America Toxicology Course 1982 Presented a lecture at American Association College Pharmacy Meeting, Kansas

City 1982 Continuing Education Lecture, Independence, Kansas 1982 Participated in Immunotoxicology Workshop, Second International Conference

on Immunotoxicology, Washington, D.C. 1983 Lectured in Mid-America Toxicology Course 1983 Participated in Third Annual Chemical Defense Bioscience Review, Aberdeen

Proving Ground, MD 1984 Lectured at German Scientific Foundation, Munich, West Germany 1984 Lectured at University of Ulm, Ulm, West Germany 1984 Lectured at Max Planck Institute 1984 Lectured at Marion Laboratories 1984 Lectured at Fourth Annual Chemical Defense Bioscience Review, Aberdeen

Proving Ground, MD 1984 Lectured at Bethel College 1985 Lectured in Mid-America Toxicology course 1985 Participated in Third Symposium on the Prophylaxis and Treatment of Chemical

Poisoning, Stockholm, Sweden 1985 Lectured at Fifth Annual Chemical Defense Bioscience Review, Columbia, MD 1985 Participated in workshop on "Seizure-Induced Neuropathology," University of

Kansas Medical Center 1985 Western Circuit course 1986 Eastern Circuit course 1986 Lectured in Mid-America Toxicology course 1986 Participated in Med Info 86, Washington, D.C. 1987 Lectured in Mid-America Toxicology course 1987 Lectured at University of Kuopio, Finland

1987 Lectured at University of Helsinki, Finland 1987 Lectured at Nordic Pharmacology Meeting, Kuopio, Finland 1987 Participated in Sixth Annual Chemical Defense Bioscience Review, Columbia,

MD 1987 Participated in Indian Health Service Medical Student Advocacy Program,

Denver, CO 1988 Participated in Indian Health Service Medical Student Advocacy Program,

Anchorage, Alaska

Curriculum Vitae Thomas Lowell Pazdernik Page 16 1988 Participated in Indian Health Service Medical Student Advocacy Program, Bethel,

Alaska 1988 Lectured in Mid-America Toxicology Course 1988 Lectured in Neuroscience course, University of Kansas, Lawrence, Kansas 1988 Participated in Central States General Medical Education Meeting, Milwaukee,

WI 1989 Lectured in Mid-America Toxicology Course 1990 Lectured in Mid-America Toxicology course 1990 Lectured at University of Helsinki, Finland 1990 Lectured at University of Kuopio, Finland 1990 Lectured at University of Tampere, Finland 1990 Lectured at University Oulu, Finland 1990 Planning Committee, "Oxygen Free Radicals in Tissue Damage," Kansas City,

KS 1991 Lectured in Mid-America Toxicology Course 1992 AMSP Annual Chairman's Meeting, Sea Island, Georgia 1992 Lectured in Mid-America Toxicology Course 1992 Participated in Symposium on Multiple Chemical Sensitivities, Arlington, Virginia 1993 Lectured in Mid-America Toxicology Course 1993 Participated in 1993 Medical Defense Bioscience Review, Baltimore 1994 AMSA Teaching Symposium, Sea Island, Georgia 1994 Lectured in Mid-America Toxicology Course 1994 Lectured in Toxicology Course, Prague, Czech 1994 Spent two weeks at University of Magdeburg, Germany. Presented seminar. 1994 Seminar, Department of Anatomy and Physiology, Kansas State University 1995 Lectured in Mid-America Toxicology Course 1995 IDEA Symposium and Work Session: Organizer; Redox Regulation of Early Gene Expression, Kansas City 1996 Speaker, Bioscience Review, Baltimore 1996 Lecture in Nordic Neurotoxicology Course, Kuopio, Finland 1996 Lectured in Mid-America Toxicology Course 1996 IDEA Symposium and Work Session: Organizer; Redox Regulation of Proteins, Lawrence, KS 1996 Seminar, Department of Analytical Chemistry, University of Kansas, Lawrence 1996 IDEA Symposium and Work Session: Organizer; Nitric Oxide in the Nervous System, Kansas City 1996 IDEA Symposium and Work Session: Organizer; Oxidative Regulation in Gene Expression: Role in Neurodegenerative Diseases, Kansas City 1997 Seminar, Department of Pharmacology and Therapeutics, University of Kansas, Lawrence 1997 Participated in Faculty Development Work Shop, Kansas City 1997 Work Shop on Problem -Based Learning; Wichita State University 1997 Lectured in Mid-America Toxicology Course 1998 Presentation to Occupational Physicians, Kansas City, MO

Curriculum Vitae Thomas Lowell Pazdernik Page 17 1998 Pharmacology Board Review, University Health Sciences (5 hours) 1998 Lectured in Mid-America Toxicology Course 1998 Pharmacology Board Review, KUMC (5 hours) 1998 Psychiatry Grand Rounds 1997 Presentation at Fourth International Metallothionein Meeting, KC,MO 1998 Presentation at 1998 Bioscience Review, Baltimore 1998 Presentation to Psychiatry Residents on Neurobiology of Stress 1999 Lectured in Mid-America Toxicology Course 1999 Pharmacology Board Review, University Health Sciences (5 hours) 1999 Pharmacology Course, University of Antigua (42 hours) 2000 Presentation to Psychiatry Residents on Neurobiology of Stress 2000 Lectured in Mid-America Toxicology Course 2000 Pharmacology Board Review, University Health Sciences (5 hours) 2000 Pharmacology Course, University of Antigua (42 hours) 2000 Pharmacology Course, University Health Sciences (12 hours) 2000 Toxicology Course, Univ. Kansas, Lawrence Kansas (3 hours) 2001 Lectured in Mid-America Toxicology Course (4 hours) 2001 Pharmacology Board Review, University Health Sciences (6 hours) 2001 Anticoagulants, University Health Sciences (2 hours) 2001 Presentation to Psychiatry Residents on Neurobiology of Stress 2002 Toxicology Course, Univ. Kansas, Lawrence Kansas (3 hours) 2002 Lectured in Mid-America Toxicology Course (2 hours) 2002 Pharmacology Board Review, University Health Sciences (2 hours) 2002 Integrative Course, University Health Sciences (12 hours) 2002 Presentation to Psychiatry Residents on Neurobiology of Stress 2002 Anticoagulants, University Health Sciences (2 hours) 2003 Lectured in Mid-America Toxicology Course (2 hours) 2003 Presentation to Psychiatry Residents on Neurobiology of Stress 2003 Pharmacology Board Review, University Health Sciences (2 hours) 2003 Integrative Course, University Health Sciences (12 hours) 2004 Presentation to Psychiatry Residents on Neurobiology of Stress (2 hours) 2004 Integrative Course, University Health Sciences (12 hours) 2004 Lectured in Mid-America Toxicology Course (5 hours) 2004 KU Premed Club 2004 Anticoagulants, University Health Sciences (2 hours) 2005 Integration of the Basic Sciences into the Study of Pharmacology, KUMC 2005 Psychiatry Grand Rounds (1 hour) 2005 Lectured in Mid-America Toxicology Course (5 hours) 2005 Integrative Course, University Health Sciences (12 hours) 2005 Board Prep: General Principles (1 hour) 2005 Board Prep: Autonomic Drugs (1 hour) 2005 Anticoagulants, Kansas City University of Medicine and Biosciences (2 hours) 2005 Presentation to Psychiatry Residents on Neurobiology of Emotions (2 hours) 2005 Internet Professors, Houston Texas; 15 hours of Streaming Video; Board Review

Curriculum Vitae Thomas Lowell Pazdernik Page 18 2005 KU Premed Club 2005 Health Careers Pathways Program: College Visitation Day 2005 KUMC Women in Medicine Presentation 2006 Integration of the Basic Sciences into the Study of Pharmacology, KUMC 2006 Lectured in Mid-America Toxicology Course (2 hours) 2006 Integrative Course, University Health Sciences (12 hours) 2006 Board Prep: General Principles (1 hour) 2007 Board Prep: Autonomic Drugs (1 hour) 2006 Presentation to Psychiatry Residents on Neurobiology of Emotions (2 hours 2008 Integration of the Basic Sciences into the Study of Pharmacology, KUMC 2007 SOM Educators Breakfast: Question Writing Board Prep: 2007 General Principles (1 hour) 2007 Board Prep: Autonomic Drugs (1 hour) 2007 Lectured in Mid-America Toxicology Course (2 hours) 2007 India Mid-America Toxicology course (4 hours) 2007 Presentation to Psychiatry Residents on Neurobiology of Emotions (2 hours) 2008 Lectured in Mid-America Toxicology Course (2 hours) 2008 Prematriculation program; Exam taking skills (6 hours) 2009 Lectured in Mid-America Toxicology Course (2 hours) 2009 Prematriculation program; Exam taking skills (6 hours) 2009 Presentation to Psychiatry Residents on Neurobiology of Stress (2 hours) Publications: Papers: 1. Portoghese, P.S., T.L. Pazdernik, W.L. Kuhn, G. Hite, and A. Shafiee.

Stereochemical studies on medicinal agents. V. Synthesis, configuration, and pharmacological activity of pipradrol enantiomers. J. Med. Chem. 11:12-15, 1968.

2. Smissman, E.E., and T.L. Pazdernik. A conformational study of the

phenethylamine receptor site. I. The synthesis of semirigid analogs of α-methylamphetamine. J. Med. Chem. 16:14-18, 1973.

3. Smissman, E.E., and T.L. Pazdernik. A conformational study of the

phenethylamine receptor site. II. The syntheses of rigid analogs of α-methylamphetamine. J. Med. Chem. 16:18-23, 1973.

4. Tuomisto, J., E.E. Smissman, T.L. Pazdernik, and E.J. Walaszek. Decalin

analogs of phenethylamines as inhibitors of amine uptake by rabbit platelets. I. Uptake and distribution of histamine. J. Pharm. Sci. 63:1708-1713, 1974.

Curriculum Vitae Thomas Lowell Pazdernik Page 19 5. Tuomisto, J., E.J. Walaszek, E.E. Smissman, and T.L. Pazdernik. Decalin

analogs of phenethylamines as inhibitors of amine uptake by rabbits. II. Uptake of 5-hydroxytryptamine. J. Pharm. Sci. 63:1714-1718, 1974.

6. Pazdernik, T.L., and E.M. Uyeki. An in vitro primary response to 2,4,5-

trinitrophenol substituted erythrocytes. Immunology 24:823-830, 1974. 7. Tuomisto, J., E.J. Walaszek, and T.L. Pazdernik. Inhibition of histamine uptake

in platelets by some alkaloids. Ann. Med. Exp. Biol. Fenniae 51:59-64, 1973. 8. Pazdernik, T.L., and E.M. Uyeki. Carrier- and hapten-antibody producing cells in

vitro. I. Cytokinetics. Proc. Soc. Exp. Biol. Med. 144:232-237, 1974. 9. Pazdernik, T.L., and E.M.Uyeki. Carrier- and hapten-antibody producing cells, in

vitro. II. Effects of purine antimetabolites. Agents Actions 4:15-30, 1974. 10. Pazdernik, T.L., and E.M. Uyeki. Carrier- and hapten-antibody producing cells, in

vitro. IV. Effects of puromycin. Res. Commun. Chem. Pathol. Pharmacol. 6:591-600, 1974.

11. Uyeki, E.M., A. ElAshkar, and T.L. Pazdernik. Effects of "Bordetella Pertussis"

on hemic colony-forming cells and the immune response. Agents Actions 4:271-276, 1974.

12. Pazdernik, T.L., and E.M. Uyeki. Enhancement of the radioprotective effects of

2-mercaptoethylamine on colony-forming cells by agents which alter cyclic nucleotide levels. Int. J. Radiat. Biol. 26:331-340, 1974.

13. Pazdernik, T.L., and E.M. Uyeki. Effects of allogenic and effector cells on the

development of antibody-producing cells, in vitro. Proc. Soc. Exp. Biol. Med. 150:654-659, 1975.

14. Uyeki, E.M., and T.L. Pazdernik. Pharmacological selectivity in immunosuppression. In: Proceedings of the Sixth International Congress of Pharmacology (Ed., J. Tuomisto and M.K. Paasonen), Vol. 4, 181-190, 1975.

15. Smissman, E.E., R.J. Murray, J.D. McChesney, L.L. Houston, and T.L.

Pazdernik. Podophyllotoxin analogs. I. Synthesis and biological evaluation of certain Trans-m-aryl-trans-6-hydroxy-methyl-3 cyclohexencarboxylic acid -lactones as antimitotic agents. J. Med. Chem. 19:148-153, 1976.

Curriculum Vitae Thomas Lowell Pazdernik Page 20 16. Faraj, B.A., Z.H. Israeli, N.E. Knight, E.E. Smissman, and T.L. Pazdernik.

Specificity of antibody directed against d-methamphetamines. Studies with rigid and nonrigid analogs. J. Med. Chem. 19:20-25, 1976.

17. Tuomisto, J., L. Tuomisto, and T.L. Pazdernik. Conformationally rigid

amphetamine analogs as inhibitors of monamine uptake by brain synaptosomes. J. Med. Chem. 19:725-727, 1976.

18. Uyeki, E.M., T.L. Pazdernik, and A. ElAshkar. Toxicity of antitumor agents on

hemopoietic colony forming cells. J. Pharmacol. Exp. Ther. 198:246-253, 1976. 19. Pazdernik, T.L., and T. Nishimura. Radiosensitivity of different B and T

subpopulations of lymphocytes in the mouse spleen. Agents Actions 8:229-237, 1978.

20. Pazdernik, T.L., and T. Nishimura. A new technique for detecting the immediate

precursor of the antigen reactive cell in mouse bone marrow. J. Immunol. Methods 23:353-374, 1978.

21. Pazdernik, T.L., and E.M. Uyeki. Cyclophosphamide. I. Effects on survival and

colony-forming cells in BDF1 L-1210-bearing mice. J. Pharmacol. Exp. Ther. 207:255-261, 1978.

22. Wierda, D., and T.L. Pazdernik. Suppression of spleen lymphocyte mitogenesis

in mice injected with platinum compounds. Eur. J. Cancer 15:1013-1022, 1979. 23. Wierda, D., and T.L. Pazdernik. Effects of cyclophosphamide on hemic

precursor cells in mouse bone marrow and spleen. J. Immunopharmacol. 1:357-376, 1979.

24. Wierda, D., and T.L. Pazdernik. Toxicity of platinum complexes on hemopoietic

precursor cells. J. Pharmacol. Exp. Ther. 211:531-538, 1979. 25. Pazdernik, T.L., and M.D. Corbett. Effects of chloramphenicol reduction products

on hemopoietic precursor cells in vitro. Pharmacology 19:191-195, 1979. 26. Colwell, M., R. Meyer, T. Pazdernik, and J. Halsey. Immunologic tolerance to

dinitrophenylated-HgG induced via colostrum. Cell. Immunol. 52:229-238, 1980.

27. Pazdernik, T.L., and M.D. Corbett. Role of chloramphenicol reduction products in aplastic anemia. Pharmacology 20:87-94, 1980.

28. Pazdernik, T.L. Immunopharmacology: Regulation of precursor cells. Med. Biol.

58:63-75, 1980.

Curriculum Vitae Thomas Lowell Pazdernik Page 21 29. Wierda, D., and T.L. Pazdernik. Uridine transport in concanavalin A- and

lipopolysaccharide-activated mouse lymphocytes. Biochem. Pharmacol. 30:3295-3303, 1981.

30. Pazdernik, T.L., R.S. Cross, K. Mewes, F. Samson, and S.R. Nelson. Superior

colliculus activation by retinal nicotinic ganglion cells: A deoxyglucose study. Brain Res. 243:197-200, 1982.

31. Pazdernik, T.L., and E.J. Walaszek. A computer assisted teaching system

(CATS) in pharmacology for health professionals. J. Med. Educ. 58:341-345, 1983.

32. Stelzer, K., and T.L. Pazdernik. Effects of cadmium on humoral immunity. Int. J.

Immunopharmacol. 5:541-548, 1983. 33. Kent, T.A., T.L. Pazdernik, W.H. Gunn et al. Platelet uptake of serotonin in

ethanol intoxication. Biol. Psychiatry 18:929-933, 1983. 34. Eigenberg, D.A., T.L. Pazdernik, and J. Doull. Hemoperfusion and

pharmacokinetics studies with methamidophos in the rat. Fundament. Appl. Toxicol. 3:496-501, 1983.

35. Eigenberg, D.A., T.L. Pazdernik, and J. Doull. Hemoperfusion and

pharmacokinetic studies with parathion and paraoxon in the rat and dog. Drug Metab. Dispos. 11:366-370, 1983.

36. Pazdernik, T.L., R. Cross, S. Nelson, F. Samson, and J. McDonough, Jr.

Soman-induced depression of brain activity in TAB-pretreated rats: 2-deoxyglucose study. Neurotoxicology 4:27-34, 1983.

37. Churchill, L., T.L. Pazdernik, F. Samson, and S.R. Nelson. Topographical

distribution of down-regulated muscarinic receptors in rat brains after repeated exposure to diisopropyl fluorophosphate. Neuroscience 11:463-472, 1984.

38. Pazdernik, T.L., and J. Tuomisto. Dopamine and 5-HT uptake by synaptosomes

after pretreatment with p-chlorophenylalanine. Med. Biol. 61:264-267, 1983. 39. Chastain, J.E., and T.L. Pazdernik. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-

induced immunotoxicity. Int. J. Immunopharmacol. 7:849-856, 1985. 40. Samson, F.E., T.L. Pazdernik, R.S. Cross, M.P. Giesler, K. Mewes, S.R. Nelson,

and J.H. McDonough. Soman induced changes in brain regional glucose use. Fundament. Appl. Toxicol. 4:S173-S183, 1984.

Curriculum Vitae Thomas Lowell Pazdernik Page 22

41. Pazdernik, T.L., R.S. Cross, M. Giesler, K. Mewes, F.E. Samson, and S.R.

Nelson. A comparison of changes in local cerebral glucose utilization by various convulsants. Neuroscience 14:823-835, 1985.

42. Churchill, L., T.L. Pazdernik, J.L. Jackson, S.R. Nelson, F.E. Samson and J.H.

McDonough. Topographical distribution of decrements and recovery in muscarinic receptors from rat brains exposed to sublethal doses of soman. J. Neuroscience 4:2069-2079, 1984.

43. Churchill, L., T.L. Pazdernik, J.L. Jackson, S.R. Nelson, F.E. Samson, J.H.

McDonough, and C. McLeod. Neuropathology in selected brain regions after repeated doses of soman to rats: Muscarinic receptor autoradiography and dark field photography of unstained sections reveal gross lesions. Neurotoxicology 6:81-90, 1985.

44. Pazdernik, T.L., R. Cross, M. Giesler, S. Nelson, F. Samson, and J. McDonough.

Delayed effects of soman: Brain glucose use and pathology. Neurotoxicology 6:61-70, 1985.

45. Pazdernik, T.L., F.E. Samson, R. Cross, M. Giesler, J. Jackson, and S.R.

Nelson. Brain regional energy flow: Effects of the pretreatment with valium in soman exposed rats. Proceedings of the Fourth Annual Biosciences Review. pp. 437-449, U.S. Army Medical Research and Development Command, Aberdeen Proving Ground, Maryland, 1984.

46. Kent, T.A., J.L. Campbell, T.L. Pazdernik, R. Hunter, W.H. Gunn, and D.W.

Goodwin. Blood platelet uptake of serotonin in chronic alcoholics. J. Alcohol Studies 46:357-359, 1985.

47. Pazdernik, T.L., and Rozman, K.K. Effect of thyroidectomy and thyroxine on

2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immunotoxicity. Life Sci. 36:695-703, 1985.

48. Rozman, K., T. Rozman, E. Scheufler, T. Pazdernik, and H. Greim. Thyroid

hormones modulate the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). J. Toxicol. Environ. Health 16:481-491, 1985.

49. Samson, F., T. Pazdernik, R. Cross, L. Churchill, M. Giesler, and S. Nelson.

Brain regional activity and damage associated with organophosphate induced seizures: Effects of atropine and benactyzine. Proc. West. Pharmacol. Soc. 28:183-185, 1985.

Curriculum Vitae Thomas Lowell Pazdernik Page 23 50. Churchill, L., T.L. Pazdernik, S.R. Nelson, and F.E. Samson. Muscarinic

receptor maps reveal selective brain damage in soman exposed rats; Diazepam prevents this damage. Proceedings of the Fifth Annual Biosciences Review, U.S. Army Medical Research and Development Command, Columbia, Maryland, 475-488, 1985.

51. Pazdernik, T.L., S.R. Nelson, R. Cross, L. Churchill, M. Giesler, and F.E.

Samson. Effects of antidotes on soman-induced brain changes. Arch. Toxicol., Suppl. 9, 333-336, 1986.

52. Pazdernik, T.L., L. Churchill, S.R. Nelson, R. Cross, M. Giesler, and F.E. Samson. Atropine or benactyzine modifies local cerebral glucose use in soman-induced seizures and subsequent brain damage. Proceedings of the Fifth Annual Biosciences Review, U.S. Army Medical Research and Development Command, Columbia, Maryland, 1985.

53. Churchill, L., T.L. Pazdernik, R.S. Cross, M.P. Giesler, S.R. Nelson, and F.E.

Samson. Cholinergic systems influence excitation and inhibition of local cerebral glucose use in specific anatomical areas: Diisopropyl phosphorofluoridate versus soman. Neuroscience 20:329-339, 1987.

54. Pazdernik, T.L., F.E. Samson, and S.R. Nelson. Soman's action on the brain.

In: Synthesis and Application of Isotopic Labeled Compounds, R.R. Muccino (Ed.), 415-420, 1985.

55. Wade, J.V., F.E. Samson, S.R. Nelson, and T.L. Pazdernik. Changes in

extracellular amino acids during soman- and kainic acid-induced seizures. J. Neurochem. 49:645-650, 1987.

56. Wade, J.V., F.E. Samson, S.R. Nelson, and T.L. Pazdernik. Extracellular taurine

levels increase in rat piriform cortex during seizures induced by systemic soman injection but not by direct soman microdialysis perfusion. Sixth Bioscience Reviews (U.S. Army Research and Development Command), pp. 433-436, 1987.

57. Chastain, J.E., F. Samson, S. Nelson, and T.L. Pazdernik. Attenuation of

cerebral glucose use in kainic acid-treated rats by diazepam. Eur. J. Pharmacol. 142:215-224, 1987.

58. Chastain, J.E., F. Samson, S. Nelson, and T.L. Pazdernik. Kainic acid-induced

seizures: Changes in brain extracellular ions as assessed by intracranial microdialysis. Life Sci 45:811-817, 1989.

Curriculum Vitae Thomas Lowell Pazdernik Page 24 59. Chastain, J.E., F. Samson, S. Nelson, and T.L. Pazdernik. Effects of

microdialysis on brain function in normal and seizure states. Neuroscience 37:155-161, 1990.

60. Chastain, J.E., F. Samson, S. Nelson, and T.L. Pazdernik. Time dependent

changes in glucose utilization associated with kainic acid-induced seizures. 61. Wade, J.V., J.P. Olson, F.E. Samson, S.R. Nelson, and T.L. Pazdernik. A

possible role for taurine in osmoregulation within the brain. J. Neurochem. 51:740-745, 1988.

62. Savolainen, K.M., S.R. Nelson, F.E. Samson, and T.L. Pazdernik. Soman-

induced convulsions affect the inositol lipid signalling system: Potentiation by lithium; attenuation by atropine and diazepam. Toxicol. Appl. Pharmacol. 96:305-314, 1988.

63. Savolainen, K., T.B. Terry, S.R. Nelson, F.E. Samson and T.L. Pazdernik.

Convulsions and cerebral inositol-1-phosphate levels in rats treated with diisopropyl fluorophosphate. Pharmacology and Toxicology 63:137-138, 1988.

64. Pazdernik, T.L., J.V. Wade, S.R. Nelson and F.E. Samson. Is taurine involved in cerebral osmoregulation? In: Functional Neurochemistry of Taurine, Alan Liss, Inc., pp. 377-384, 1990.

65. Samson, F., S.R. Nelson, R.S. Cross and T.L. Pazdernik. Sub-lethal doses of

sodium cyanide depress brain glucose utilization. Proceeding of the 1989 Medical Defense Bioscience Review. (U.S. Army Medical Research and Development Command) pp. 83-86, 1989.

66. Savolainen, K.M., M.R. Hirvonen, J. Tarhanen, S.R. Nelson, F.E. Samson and

T.L. Pazdernik. Changes in cerebral inositol-1-phosphate concentrations in LiCl-treated rats: Regional and Strain Differences. Neurochemical Research 15:511-545, 1990.

67. Churchill, L., T.L. Pazdernik, R.S. Cross, S.R. Nelson and F.E. Samson. Soman

and kainic acid-induced convulsions decrease muscarinic receptors without changing benzodiazipine receptors. Neurotoxicology 11:57-72, 1990.

68. Terry, J.B., T.L. Pazdernik, and S.R. Nelson. Effect of LiCl pretreatment on

cholinomimetic-induced seizures and seizure-induced brain damage. Neuroscience Letters 114:123-127, 1990.

69. Churchill, L., R.S. Cross, T.L. Pazdernik, S.R. Nelson, D.S. Zahm, L. Heime, K.P.

Diltz, and P.W. Kalivas. Patterns of glucose use after bicuculline-induced

Curriculum Vitae Thomas Lowell Pazdernik Page 25

convulsions in relationship to t-amino-butyric acid and opiod receptors in the ventral pallidum--functional marking for the ventral pallidum. Brain Res. 581:39-45, 1992.

70. Savolainen, K.M., O. Muona, S.R. Nelson, F.E. Samson, and T.L. Pazdernik.

Lithium modifies convulsions and brain phosphoinositide turnover induced by organophosphates. Pharmacology and Toxicology 68:346-354, 1991.

71. Pazdernik, T.L., S.R. Nelson, R. Cross, H. Zuo and F. Samson. Cyanide actions

on brain metabolism. Proceedings of the 1991 Medical Defense Bioscience Review (U.S. Army Medical Research Institute of Chemical Defense), pp 265-268.

72. Pazdernik, T.L., M. Layton, S.R. Nelson, F.E. Samson. The osmotic/calcium

stress theory of brain damage: Are free radicals involved? Neurochem. Res. 17:11-21, 1992.

73. Nelson, S.R., T.L. Pazdernik and F.E. Samson. Copper plus ascorbate

inactivates lactate dehydrogenase: Are oxygen radicals involved? Proc. West. Pharmacol. Soc. 35:37-41, 1992.

74. Layton, M.E. and T.L. Pazdernik. Reactive oxygen species in rat brain

extracellular fluid. In: Oxygen Free Radicals in Tissue Damage, C.M. Tarr and F.E. Samson (Eds.), Burkhauser, Boston, MA, pp. 105-131, 1992.

75. Pazdernik, T., R. Cross, S. Nelson, Y. Kamijo and F. Samson. Is there an

energy conservation "system" in brain that protects against the consequences of energy depletion. Neurochemical Research 19:1393-1400, 1994.

76. Pazdernik, T. L. Toxicology. In: Basic Pharmacology in Medicine, Eds.

J.R.DiPalma, G.J. DeGregorio, E.J. Barbieri, A.P. Ferko, 4th ed, pp 803-809, Medical Surveillance, Inc.. Westchester (1994).

77. Pazdernik, T.L. Non-metallic toxicants. In: Basic Pharmacology in Medicine,

same, pp 810- 820. 78. Pazdernik, T.L. Heavy metals and antagonists. In: Basic Pharmacology in

Medicine, same, pp 821-834. 79. Dalton, T., T.L. Pazdernik, J. Wagner, F.E. Samson, G.K. Andrews.

Temporalspatial patterns of expression of metallothionein I and III and other stress proteins after kainic acid-induced seizures. Neurochem. Int.,27:59-71, 1995.

Curriculum Vitae Thomas Lowell Pazdernik Page 26 80. Schmitt U., R, Cross, T. L. Pazdernik, B.H. Sabel. Loss and subsequent

recovery of local glucose use invisual targets after controlled optic nerve crush in adult rats. Experimental Neurology 139, 17-24, 1996.

81. Enna, S.J., M.A. Gordon, T.L. Pazdernik (editors) “Mosby’s Ace the Boards: Pharmacology, Mosby, St. Louis, 1996. 82. Pazdernik, T. L. General Principles of Pharmacology, In: Mosby’s Ace the

Boards: Pharmacology(Eds., S.J. Enna, M.A. Gordon, T.L. Pazdernik) Mosby, St. Louis, 1996.

83. Zhang, Y., F. E. Samson, S.R. Nelson, and T. L. Pazdernik. Nitric oxide detection

with intracerebral microdialysis: Important considerations in the application of the hemogolobin-trapping technique. J Neurosc. Methods 68, 165-173, 1996.

84. Layton, M.E., J.K. Wagner, F.E. Samson and T. L. Pazdernik. Redox changes in

perfusates following intracerebral penetration of microdialysis probes. Neurochem Res. 22, 735-741, 1997.

85. Pazdernik, T.L., S.R. Nelson, R. Cross and F.E. Samson. Chemical-induced

Seizures: Free radicals asfinal common pathway, Proceeding of 1996 Medical Bioscience Review, Volume I, 413-422, 1997.

86. Schmitt, U., B.A. Sabel, R. Cross, F.E. Samson and T.L. Pazdernik. Recovery of

metabolic activity in retinofugal targets after traumatic optic nerve injury is independent of retinofugal input. Restorative Neurobiology and Neurosciences 13: 153-161, 1998.

87. Layton, M.E., F.E. Samson and T.L.Pazdernik. Kainic acid causes redox

changes in cerebralextracellular fluid: NMDA receptor activity increases ascorbic acid whereas seizure activity increases uric acid.Neuropharmacology 37: 149-157, 1998.

88. Layton, M.E., T. L. Pazdernik and F.E. Samson. Cerebral Penetration Injury

Leads to H2O2 Generation. Neurosci. Lett.,236: 63-66, 1997. 89. Emerson, M.R, R.S. Cross, S Jin, F.E. Samson and T.L. Pazdernik.

Metallothionein-1,2 and heme oxygenase-1 are expressed in damaged brain regions following chemically-Induced seizures. Metallothionein IV C. Klaassen (ed.) pp. 351-357, 1999.

90. Pazdernik, T.L., M.R. Emerson, R. Cross, S.R. Nelson and F.E. Samson.

Soman-induced seizures: Limbic activity, Oxidative stress and Neuroprotective

Curriculum Vitae Thomas Lowell Pazdernik Page 27

proteins. Proceedings of 1998 Medical Bioscience Review,(U.S. Army Medical Research Institute of Chemical Defense), pp 1-15, 1999.

91. Emerson, M.R., S.R. Nelson, F.E. Samson and T.L. Pazdernik. Hypoxia

preconditioning attenuates brain edema associated with kainic acid-induced status epilepticus in rats. Brain Research 825: 189-193, 1999.

92. Pazdernik, T. L., L. Kerecsen, M.K. Shaw (authors) Rapid Review of

Pharmacology , Mosby, St. Louis, 2003. 93. Levant, B. R.S. Cross, and T. L. Pazdernik. Alterations in Local Cerebral

Glucose Utilization produced by D3 dopamine receptor-selective doses of 7-OH-DPAT and Nafadotride. Brain Res. 812:193-199, 1998.

94. Emerson, M.R., S.R. Nelson, F.E. Samson and T.L. Pazdernik. A global hypoxia-

preconditioning model for neuroprotection in the rat: Brain edema and neuropathology studies. Brain Research Protocols. 4:360-366,1999.

95. Romanas, M.M., M.R. Emerson, S.R. Nelson, F.E. Samson and T.L. Pazdernik.

Does extracellular Ascorbate Promote Oxidative Damage in the Aging Brain. Ann. N.Y. Acd. Sci. 854:493, 1998.

96. Layton, ME and Pazdernik, TL Reactive oxidant species in piriform cortex

extracellular fluid during seizures induced by systemic kainic acid in rats. J. Mol. Neurosci. 13:63-68, 1999.

97. Emerson, M.R., F.E. Samson and T.L. Pazdernik. Effects of Hypoxia

Preconditionig on Expression of Metallothioein-1,2 and Heme Oxygenase-1 before and after kainic acid-induced seizures. Cellular and Molecular Biology. 46:619 - 626, 2000.

98. Nelson, S.R., T. L. Pazdernik and F.E. Samson. Measurement of Loosely-Bound

Iron in Brain Regions using Redox Cycling and Salicylate. Cellular and Molecular Biology. 46:649 -655, 2000.

99. Pazdernik, T.L., M.R. Emerson, R. Cross, S.R. Nelson and F.E. Samson.

Soman-induced seizures: Limbic activity, Oxidative stress and Neuroprotective proteins. J. Appl. Toxicol.21: S87- S94, 2001.

100. Kerecsen, L. and T.L. Pazdernik. From Mainframe to Web-Based: 30 years of

Experience in Computer Aided Instruction of Pharmacology. Nauyn-Schmiedeberg’s Archives of Pharmacology 366: 83- 89, 2002.

Curriculum Vitae Thomas Lowell Pazdernik Page 28 101. Carpenter T., T.L., Pazdernik and B. Levant. Differences in quinpirole-induced

local cerebral glucose utilization between naïve and quinpirole-sensitized rats. Brain Res.964:295-301, 2003.

102. Klaidman, L.K., J.D. Adams Jr., R. Cross, T.L. Pazdernik and F. Samson.

Alterations in brain glutathione homeostasis induced by the nerve gas soman. Neurotox. Res. 5: 177-182, 2003.

103. Levant B. and T. L. Pazdernik. Differential effects of ibogaine on local cerebral

glucose utilization in drug-naïve and morphine-dependent rats. Brain Res. 1003:157-159, 2004.

104. Richards TL, TL Pazdernik and B Levant. Altered quinpirole-induced local

cerebral glucose utilization in anterior cortical regions in rats after sensitization to quinpirole. Brain Res. 1042: 53-61 (2005).

105. Richards, T.L., T.L. Pazdernik, and B. Levant. Clorgyline-induced modification of

behavioral sensitization to quinpirole: Effects on local cerebral glucose utilization. Brain Res. 1160: 124-133 (2007)

106. Pazdernik, T. L. & L. Kerecsen, (authors) Rapid Review of Pharmacology,

Mosby, Philadelphia; 2nd Ed.; (2007). 107. Richards, TL, TL Pazdernik, and B Levant. Basal local cerebral glucose use is

not altered after behavioral sensitization to quinpirole. Neuroscience Letters. 429: 165-68 (2007).

108. Myers, JS, J Pierce, and T Pazdernik. Neurotoxicology of chemotherapy in

Relation to cytokine Release, the Blood-Brain Barrier and cognitive Impairmant. Onocology Nursing Forum 35: 916—920 (2008).

109. Pazdernik, T. L. & L. Kerecsen, (authors) Rapid Review of Pharmacology,

Mosby, Philadelphia; 3rd Ed. (2011). Abstracts: 1. Pazdernik, T.L., and E.M. Uyeki. Concomitant analysis of drug effects on mixed

cell interactions and humoral antibody response in mice. Fed. Proc. 32:781, 1973.

2. Pazdernik, T.L., and E.M. Uyeki. Potentiation of the radioprotective effects of 2-

mercaptoethylamine on colony-forming cells by agents which alter cyclic nucleotide levels. Fed. Proc. 33:521, 1974.

Curriculum Vitae Thomas Lowell Pazdernik Page 29 3. Uyeki, E.M., and T.L. Pazdernik. Pharmacological selectivity in

immunosuppression. Sixth Int. Cong. Pharmacol., p. 506, 1975. 4. Pazdernik, T.L., and E.M. Uyeki. Effects of cyclophosphamide on the

development of hemopoietic colony-forming cells and tumor colony-forming cells in normal and tumor bearing mice. Sixth Int. Cong. Pharmacol., p. 1333, 1975.

5. Wierda, D., and T.L. Pazdernik. Effects of platinum complexes on B and T

lymphocytes. Fed. Proc. 36:347, 1977. 6. Pazdernik, T.L., and T. Nishimura. Development of anti-TNP-plaque forming

cells from mouse bone marrow cells, in vitro. In Vitro 13:166, 1977. 7. Wierda, D., and T.L. Pazdernik. Perturbation of bone marrow P-PFC and CFC

by platinum complexes. Pharmacologist 19:236, 1977. 8. Wierda, D., and T.L. Pazdernik. Effects of cyclophosphamide on the recovery of

leukopoiesis. Fed. Proc. 37:1512, 1978. 9. Pazdernik, T.L., and D. Wierda. Effects of busulfan and cortisone acetate on

hemopoietic precursor cells. Seventh Int. Cong. Pharmacol., p. 1352, 1978. 10. Wierda, D., and T.L. Pazdernik. Uridine transport into mitogen stimulated murine

lymphocytes. Pharmacologist 20:264, 1978. 11. Wierda, D., and T.L. Pazdernik. Uridine transport into lymphocytes is related to

activation state. Fed. Proc. 38:284, 1979. 12. Pazdernik, T.L. Role of chloramphenicol reduction products in induction of

aplastic anemia. Proceedings of the Conference on Aplastic Anemia: A stem Cell Disease. NIH Publication NO. 81-1008, p. 309, 1981.

13. Pazdernik, T.L. Effects of hydroxyurea (HU) on hemopoietic precursor cells

(HPC). Pharmacologist 22:Abst. 255, 1980. 14. Dudley, R.E., S.R. Nelson, T. Pazdernik, P. Cheney, and F.E. Samson. Regional

glucose use in rat brain during chloralose anesthesia. Pharmacologist 22:Abst. 271, 1980.

15. Eigenberg, D., T. Pazdernik, and J. Doull. Hemoperfusion: Analysis of adsorptive material for removing parathion. Pharmacologist 22:Abst. 348, 1980.

Curriculum Vitae Thomas Lowell Pazdernik Page 30 16. Nelson, S.R., T.L. Pazdernik, R.S. Cross, and F.E. Samson. Glucose use

changes in the superior colliculus after cholinergic activation and inhibition of rat retina. Neuroscience, Abst., 1980.

17. Oguchi, K., S. Nelson, T. Pazdernik, and F. Samson. Droperidol influence on

ketamine-induced behavior and brain glucose use. Am. Soc. Neurochem. 12:Abst. 145, 1981.

18. Eigenberg, D., T. Pazdernik, and J. Doull. Hemoperfusion: A possible

alternative method for treating organophosphate insecticide poisoning. Toxicologist 1:Abst. 496, 1981.

19. Goering, P.L., S.R. Nelson, T.L. Pazdernik, and F.E. Samson. Mecamylamide

(MC) inhibition of DFP retinal activation. Pharmacologist 23:Abst. 123, 1981. 20. Pazdernik, T.L. Modifications of benzene toxicity to hemopoietic precursor cells

by phenobarbital. Pharmacologist 23:Abst. 528, 1981. 21. Eigenberg, D., T. Pazdernik, and J. Doull. Analysis of hemoperfusion for the

treatment of parathion toxicity. Toxicologist 2:Abst. 176, 1982. 22. Eigenberg, D., T. Pazdernik, and J. Doull. Hemoperfusion and pharmacokinetic

studies with methamidophos. Pharmacologist 24:Abst. 312, 1982. 23. Stelzer, K., and T. Pazdernik. Cadmium-induced immunotoxicity.

Pharmacologist 23:Abst. 637, 1982. 24. Pazdernik, T.L., and J. Halsey. Effects of polychlorinated biphenyls (PCB) on B-

cell development. Int. J. Immunopharmacol. 4:326, 1982. 25. Samson, F., L. Churchill, and T. Pazdernik. Distribution of down-regulated

muscarinic receptors with DFP. Am. Soc. Neurochem., 14:Abst., 321, 1983. 26. Chastain, J.E., and T.L. Pazdernik. Acute dose and time dependent effects of

TCDD in murine B-lymphocytes in the bone marrow and the spleen. Pharmacologist 25:Abst. 11, 1983.

27. Nelson, S.R., R.S. Cross, M.P. Giesler, T.L. Pazdernik, K. Mewes, F.E. Samson,

and J.H. McDonough. Brain regional glucose use following exposure to soman and comparison with bicuculline and kainic acid. Neuroscience 9:Abst. 282.7, 1983.

Curriculum Vitae Thomas Lowell Pazdernik Page 31 28. Churchill, L., T.L. Pazdernik, F.E. Samson, S.R. Nelson, and J.H. McDonough.

Topographical distribution of decrements in and recovery of muscarinic receptor binding after repeated exposure to soman. Neuroscience 9:Abst. 282.8, 1983.

29. Rozman, K., E. Scheufler, T. Pazdernik, and H. Greim. Effect of thyroxine (T4) on TCDD toxicity in thyroidectomized rats. Toxicologist 4:Abst. 753, 1984.

30. Pazdernik, T., J. Chastain, R. Cross, M. Giesler, F. Samson, S. Nelson, and J.

McDonough. Neuropathology associated with soman and kainic acid-induced seizures: A 2-deoxyglucose study. International Symposium on Calcium Entry Blockers and Tissue Protection, p. 149, 1984.

31. Pazdernik, T., and K. Rozman. Role of thyroid hormones in TCDD-induced

immunotoxicity. Fed. Proc. 43:Abst. 495, 1984. 32. Churchill, L., T.L. Pazdernik, J.J. Jackson, S.R. Nelson, and F.E. Samson.

Neuropathology in selected brain regions after repeated sublethal doses of soman to rats: Muscarinic autoradiographic. Fed. Proc. 43:562, 1984.

33. Churchill, L., T.L. Pazdernik, R.S. Cross, M. Giesler, S.R. Nelson, and F.E.

Samson. Impact of DFP on local glucose utilization in antidote-pretreated rats. Am. Soc. Neurochem. 15:Abst. 188.1, 1984.

34. Pazdernik, T.L., R. Cross, M. Giesler, F. Samson, and S. Nelson. Impact of

various convulsants on local cerebral glucose utilization (LCGU). Ninth Int. Cong. Pharmacology, Abst. 783P, 1984.

35. Chastain, J.E., and T.L. Pazdernik. Effects of diazepam on kainic acid induced

seizures in rats: Neurotoxicity and glucose utilization. Pharmacologist 26:Abst. 485, 1984.

36. Churchill, L., J.L. Jackson, T.L. Pazdernik, S.R. Nelson, and F.E. Samson.

Receptor autoradiography, glucose utilization, and light refraction in kainic acid-induced neurotoxicity. Soc. Neuroscience. 10:Abst. 3165.11, 1984.

37. Pazdernik, T., S. Nelson, R. Cross, L. Churchill, S. Hammons, M. Giesler, and F.

Samson. Diazepam blocks many seizure-induced brain changes. Fed. Proc. 44:Abst. 4064, 1985.

38. Samson, F., L. Churchill, S. Nelson, R. Cross, S. Hammons, M. Giesler, and T.

Pazdernik. Severe cerebral depression precedes kainic acid induced convulsions. Am. Soc. Neurochem. 16:394, 1985.

Curriculum Vitae Thomas Lowell Pazdernik Page 32 39. Pazdernik, T., S. Nelson, R. Cross, L. Churchill, M. Giesler, and F. Samson.

Effects of antidotes on soman-induced brain damage. 26th Congress of the Eur. Soc. Toxicol., p. 159, 1985.

40. Olson, J.P., F.E. Samson, T.L. Pazdernik, and S.R. Nelson. Development of

brain edema after kainic acid-induced seizures in rats. Anat. Rec. 211:364, 1985.

41. Gudeman, D., J. Olson, F. Samson, T. Pazdernik, and S.R. Nelson, Atropine

does not prevent kainic acid-induced brain edema in rats. Anat. Rec. 211:74A, 1985.

42. Pazdernik, T.L., F.E. Samson, and S.R. Nelson. Soman's action on the brain: A

2[14C]-deoxyglucose study. Second International Symposium on the Synthesis and Applications of Isotopically Labeled Compounds, p. 106, 1985.

43. Churchill, L., T.L. Pazdernik, R.S. Cross, M. Giesler, S.R. Nelson, and F.E.

Samson. Impact of DFP on local glucose utilization in antidote-pretreated rats. Trans. Amer. Soc. for Neurochem. 15:177, 1985.

44. Pazdernik, T.L., L. Churchill, S.R. Nelson, R. Cross, M. Giesler, and F.E.

Samson. Atropine or benactyzine modifies local cerebral glucose use in soman-induced seizures and subsequent brain damage. Proceedings of the 5th Annual Chemical Defense Biosciences Review, USAMRDC, Aberdeen, MD, p.125, 1985.

45. Olson, J.P., F.E. Samson, T.L. Pazdernik, and S.R. Nelson. Mannitol prevents

necrotic edema associated with kainic acid-induced seizures. Soc. for Neurosci. 11:384.4, 1985.

46. Churchill, L., T.L. Pazdernik, R. Cross, M. Giesler, F. Samson, and S. Nelson.

Continuity between ventral pallidum and olfactory tubercle illustrated by prominent patterns of glucose utilization during chronically-induced seizures. Soc. for Neurosci., 11:154.10, 1985.

47. Wade, J.V., T.L. Pazdernik, and F.E. Samson. Cerebral extracellular taurine

increases during kainic induced seizures. Am. Soc. Neurochem., 17:314, 1986. 48. Chastain, J., and T. Pazdernik. Brain dialysis alters local cerebral glucose use

when used to measure brain extracellular potassium in awake rats treated with kainic acid. Toxicologist, 6:767, 1986.

Curriculum Vitae Thomas Lowell Pazdernik Page 33 49. Savolainen, K., S.R. Nelson, F.E. Samson, and T.L. Pazdernik. Lithium

potentiates soman-induced seizures and modifies alterations in cerebral myo-inositol-1-phosphate levels. Soc. for Neurosci. 12:125:14, 1986.

50. Savolainen, K.M., S.R. Nelson, F.E. Samson, and T.L. Pazdernik. Paraoxon-

induced seizures and alterations in brain regional myo-inositol-1-phosphate (M1P) levels in lithium pretreated rats. Pharmacologist 28:723, 1986.

51. Olson, J.P., F.E. Samson, T.L. Pazdernik, and S.R. Nelson. Mannitol prevents

necrotic edema associated with kainic acid induced seizures. Soc. for Neurosci. 11:384.4, 1986.

52. Olson, J.P., F.E. Samson, T.L. Pazdernik, B.L. DeWitt, and S.R. Nelson. Role of

early edema on seizure-related brain damage. Soc. of Neurosci. 12:24.15, 1986. 53. Olson, J.P., F.E. Samson, T.L. Pazdernik, V.H. Gattone, II, and S.R. Nelson. The

paucity of blood vessels in the temporal lobe may account for its susceptibility to seizure-induced damage. Soc. of Neurosci. 12: 1986.

54. Churchill, L., T.L. Pazdernik, S.R. Nelson, and F.E. Samson. Muscarinic receptor

changes in soman-treated rats with and without convulsions: An autoradiographic study. Soc. for Neurosci. 12:83.3, 1986.

55. Wade, J.V., R. Mangoo-Karin, S.R. Nelson, F.E. Samson, and T.L. Pazdernik.

Seizure induction and extracellular amino acid changes during intracranial microdialysis with kainic acid on NMDA. Fed. Proc. 46:2286, 1987.

56. Savolainen, K.M., S.R. Nelson, F.E. Samson, and T.L. Pazdernik. Elevations of

cerebral myo-inositol-1-phosphate accompany soman-induced seizures. Pharmacol. Toxicol. 60:Supplement III, 67, 1987.

57. Pazdernik, T.L. Central nervous system effects of organophosphates.

Pharmacol. Toxicol. 60:Supplement III, 34, 1987. 58. Terry, J.B., and T.L. Pazdernik. Potentiation of cholinergic-induced seizures and

seizure-induced brain edema by lithium. Midwest Student Medical Research Forum XVIII, Louisville, KY, 1987.

59. Samson, F., R. Cross, T. Pazdernik, and S.R. Nelson. 2-Deoxyglucose-6-PO4

accumulation in rat brain is reduced in rats pretreated with scopolamine and exposed to soman. J. Neurochem., S95B, 1987.

Curriculum Vitae Thomas Lowell Pazdernik Page 34 60. Savolainen, K., J.B. Terry, S.R. Nelson, F.E. Samson, and T.L. Pazdernik.

Seizures and cerebral myo-inositol-1-phosphate levels in DFP-treated rats. 28th Congress of Eur. Soc. Toxicol., Strasbourg, France, 1987.

61. Wade, J.V., J.P. Olson, S.R. Nelson, F.E. Samson, and T.L. Pazdernik. Taurine

may regulate cellular hydration and cell volume in the brain. Soc. for Neurosci. 13:37.6, 1987.

62. Savolainen, K.M., J.V. Wade, S.R. Nelson, F.E. Samson, and T.L. Pazdernik.

Cerebral inositol-1-phosphate and extracellular amino acids during convulsions induced by microdialysis of the rat deep prepiriform cortex with carbachol. Soc. for Neurosci. 13:44.18, 1987.

63. Olson, J.P., F.E. Samson, T.L. Pazdernik, V.H. Gattone, II, and S.R. Nelson.

The paucity of blood vessels in the temporal lobe may account for its susceptibility to seizure-induced damage. Soc. for Neurosci. 13:261.6, 1987.

64. Churchill, L., R. Cross, R.P. Diltz, T. Pazdernik, F. Samson, S. Nelson, and P.W.

Kalivas. Glucose use in the dorsal nucleus accumbens shell (an area high in mu-opioid receptors) increases during kainic acid-induced limbic but not during bicuculline seizures. Soc. for Neurosci. 13:376.2, 1987.

65. Nelson, S.R., G. Liang, F.E. Samson, T.L. Pazdernik, R.S. Cross and B.M.

Olivera. -Conotoxin "shaker" peptide causes increased glucose use in vestibular nuclei and cerebellum of rats and mice. Soc. for Neurosci. 14:59.6, 1988.

66. Walaszek, E., Pazdernik, T. and Doull, J. Use of computers in the teaching of

environmental health and toxicology. The 29th Congress of the European Society of Toxicology and the 3rd Congress of The Federation of The European Society of Toxicology. p.48, 1988.

67. Pazdernik, T.L., J.V. Wade, S.R. Nelson and F.E. Samson. NMDA receptor activation leads to increased extracellular taurine and neuropathology. J. Neurochem 52S S144A, 1989.

68. Pazdernik, T.L., J.V. Wade, S.R. Nelson and F.E. Samson. Is taurine involved in

cerebral osmoregulation? 12th ISN Meeting - Satellite Symposium Functional Neurochemistry of Taurine Abstracts. p. 42, 1989.

69. Chastain, J.E., R.S. Cross, F. Samson, S.R. Nelson, and T.L. Pazdernik. Time

dependent changes in brain glucose use associated with kainic acid-induced seizures. FASEB J. A3680, 1990.

Curriculum Vitae Thomas Lowell Pazdernik Page 35 70. Layton, M., and Pazdernik, T.L. Detection of reducing substances in brain

extracellular fluid via microdialysis perfusion with cytochrome C. 5th Annual M.D.-Ph.D. Conference, Aspen, Colorado, p. 6, 1990.

71. Pazdernik, T.L., S.R. Nelson, R.S. Cross and F.E. Samson. Cyanide causes

unexpected changes in brain glucose use. Europ. J. Pharmacol. 183:1541-1542, 1990.

72. Savolainen, K.M., O. Muona, F.E. Samson, S.R. Nelson and T.L. Pazdernik.

Lithium modifies convulsions and brain phosphoinositide turnover induced by organophosphates. Soc. Neurosci. 16:15.7, 1990.

73. Romanas, M.M., F.E. Samson, S.R. Nelson, and T.L. Pazdernik. Toxic and

trophic effects of neuronal stimulation. The Frederick E. Samson Symposium on Neurochemistry, Abs. #1, 1990.

74. Layton, M.E., J.W. Shaw, S.R. Nelson, F.E. Samson, and T.L. Pazdernik.

Detection of ascorbic acid release during kainic acid-induced seizures via microdialysis perfusion with cytochrome C. The Frederick E. Samson Symposium on Neurochemistry, Ab. #3, 1990.

75. Zuo, H., T.L. Pazdernik, R.S. Cross, F.E. Samson, and S.R. Nelson. Cyanide

produces reversible edema prominent in caudate and corpus callosum. The Frederick E. Samson Symposium on Neurochemistry, Ab. #5, 1990.

76. Layton, M.E., T.L. Pazdernik, S.R. Nelson and F.E. Samson. Reactive oxygen species detected by microdialysis in brain extracellular fluid increase during seizures. Soc. Neuroscience 17:578.21, 1991.

77. Zuo H., S.R. Nelson, F.E. Samson, T.L. Pazdernik and J.S. Beckman. L-

nitroarginine attenuates cerebral glucose use associated with kainic acid-induced seizures. FASEB J. 6:A5458, 1992.

78. Layton, M. E., Wagner, J. K., Nelson, S. R., Samson, F. E. and Pazdernik, T. L.

(1992), Oxidative stress and antioxidant response in rat piriform cortex associated with kainic acid-induced seizures. Society for Neuroscience Abstracts 18(2): 1603.

79. Layton, M. E., Wagner, J. K. and Pazdernik, T. L. (1992) Oxidative stress and antioxidant response during seizures in brain extracellular fluid. Abstracts from

the 7th Annual MD/PhD Student Conference: Mechanisms of Defense, July 17-20, 1992.

Curriculum Vitae Thomas Lowell Pazdernik Page 36 80. Romanas, M.M., F.E. Samson, S.R. Nelson and T.L. Pazdernik. Does urate

protect ascorbate from metal-catalyzed oxidation? Soc. Neuroscience 19:424.1993.

81. Romanas, M.M., F.E. Samson, S.R. Nelson and T.L. Pazdernik. Implications for

the impact of lactic acidosis in neurotoxicity mediated via free radicals. 11th Meeting, Central States Society of Toxicology, Kansas City, KS, Abs. #18, 1994.

82. Pazdernik, T.L., M.M. Romanas, S.R. Nelson and F.E. Samson. The effectiveness of ascorbate and urate as antioxidants at concentrations in brain extracellular fluid. FASEB 8:3912, 1994.

83. Romanas, M.M., F.E. Samson, S.R. Nelson and T.L. Pazdernik. The differential

effects of lactate and acid pH on metal-catalyzed salicylate hydroxylation: Implications for the effects of lactic acidosis on brain free radical chemistry. FASEB 8:3936, 1994.

84. Romanas, M.M., F.E. Samson, S.R. Nelson and T.L. Pazdernik. Free radicals

and brain extracellular constituents. 2nd Aging Symposium: Molecular Mechanisms of Degenerative Disease, Kansas City, MO, Abs. #31, 1994.

85. Romanas, M.M., F.E. Samson, S.R. Nelson and T.L. Pazdernik. Hematin could

be a potent catalyst for free radical generation in brain extracellular fluid. Soc.Neuroscience 20:180.14, 1994.

86. Schmitt, U., B.A. Sabel, R. Cross, F.E. Samson and T.L. Pazdernik. Time-

dependent effects of optic nerve cruch on superior colliculus local cerebral glucose use. Soc. Neuroscience 20:583.11, 1994.

87. Romanas, M.M., F.E. Samson, S.R. Nelson and T.L. Pazdernik. The antioxidant

capacity of human cerebrospinal fluid. EPSCOR/SBIR Conference, 1994. 88. Dalton, T., T.L. Pazdernik, J. Wagner, F.E. Samson and G.K. Andrews.

Temporalspatial patterns of expression of metallothionein-I and -III and other stress-related genes in rat brain after kainic acid induced seizures. EPSCOR/SBIR, 1994.

89. Dalton, T., T.L. Pazdernik, J. Wagner, F.E. Samson and G.K. Andrews. Oxidative

stress associated with seizures: Temporalspatial patterns of gene expression. Therapeutic Potentials of Biological Antioxidants, Tiburon Abs 81, 1994.

90. Schmitt, U., B.A. Sabel, R. Cross, F.E. Samson and T. Pazdernik. Local cerebral

glucose use in retinofugal targets after partial and total retinal deafferentation. Soc. Neuroscience. 21: 656.18, 1995.

Curriculum Vitae Thomas Lowell Pazdernik Page 37 91. Romanas, M.M., F.E. Samson, S.R. Nelson and T.L. Pazdernik. Hydroxyl

radicals in human cerebral spinal fluid. International Congress of Toxicology-VII, Abs #9-P2, July 1995.

92. Schmitt, U., T. Pazdernik and B.A. Sabel. Dissociation of anatomical, metabolic

and behavioral parameters after traumatic optic nerve injury in the adult rat. Brain Plasticity, July 1995.

93. Zhang, Y., F.E. Samson, S.R. Nelson and T.L. Pazdernik. Capture of nitric oxide

with hemoglobin in brain microdialysis. Abstract submitted to Soc. Neuroscience. 21:771.10, 1995.

94. Emerson, M.R., F.E. Samson and T.L. Pazdernik. Effectiveness of antioxidants

against oxidation of cis-paranaric acid enriched liposomes. Soc. Neuroscience 21: 394.11,1995.

95. Pazdernik, T.L., S.R. Nelson, R. Cross, F.E. Samson, Chemical-induced

seizures: Free radicals as a final common pathway. 1996 Medical Defense Bioscience Review, p. 74, 1996.

96. Emerson, M.K, F.E. Samson, and T.L. Pazdernik. Evidence for an Ascorbate-

copper-peroxide complex in lipid peroxidation. Soc. Neuroscience 22: 562.3, 1996.

97. Emerson, M.R., F.E. Samson and T.L. Pazdernik. The formation of

ascorbate-copper-hydrogen peroxide complex may be critical in lipid peroxidation. Central States-Society Toxicology 13th Annual Meeting Abstracts, 1996.

98. Romanas, M.M., M.R. Emerson, F.E. Samson, S.R. Nelson,T.L. Pazdernik .

Metal-dioxygen complexes are critical in the pro-oxidant actions of ascorbate. The Oxygen Society 3rd Annual Meeting, 1-79, 1996.

99. Emerson, M.R., M.M. Romanas, F.E. Samson and T.L. Pazdernik. Antioxidant

properties of cerebrospinal fluid and prevention of oxidation of cis-parinaric acid enriched liposomes. Oxygen Club of California Annual Meeting, p. 111, 1997.

100. Romanas, M.M. M.R. Emerson, S.R. Nelson, F.E. Samson, and T.L. Pazdernik.

Human cerebrospinal fluid and pro-oxidant actions of ascorbate. SEP/ALSA Symposium, Kansas City, Misosuri, p. 56, 1997.

101. Schroeder, H., A. Becker, T.L. Pazdernik and V. Hoelt. Specific 3H-L-glutamate

binding and K+-stimulated 3H-D-aspartate release from hippocampal tissue in the

Curriculum Vitae Thomas Lowell Pazdernik Page 38

development of pentylenetetrazol-induced kindling in rats. Soc Neurosci. 23: 839.8, 1997.

102. Emerson, M.R., F.E. Samson, S.R. Nelson and T.L. Pazdernik. Pre-exposure to

mild hypxia attenuates the brain edema associateed with kainic acid-induced status epilepticus. Soc Neurosci. 23: 319.9, 1997.

103. Pazdernik, T.L., R. Cross, S.R. Nelson and F.E. Samson. The nerve agent

soman attenuates the clearance of metabolic anions out of the brain. Soc Neurosci. 23: 749.13, 1997.

104. Kerecsen, L. and T.L. Pazdernik, WebCAI, a novel system in computer aided

instruction using the world wide web in teaching pharmacology.The Pharmacologist, 39: p 38, 1997

105. Pazdernik, T.L., R. Cross, M.R. Emerson, S. Jin and F.E. Samson. Soman

induced seizures increase brain metallothioneins. Fourth International Metallothionein Meeting , Abs #76, 1997.

106. Emerson, M.R., F.E. Samson and T.L. Pazdernik. Metallothionein-I,II and heme

oxygenase-1 are expressed in damaged brain regions following kainic acid-induced seizures. Fourth International Metallothionein Meeting Abs # 111, 1997.

107. Romanas, M.M,, M.R. Emerson, S.R. Nelson, F.E. Samson and T.L. Pazdernik.

Does extracellular ascorbate promote oxidative damage to the aging brain? 7th congress International Association of Biomedical Gerontology Abs #57P, 1997.

108. Nelson, S.R,, T.L. Pazdernik and F.E. Samson. Catalytic iron may extend

seizure-related brain damage in rats. Soc. Neurosci. Abst. 24: 178.21, 1998. 109. Emerson, M.R. , F.E, Samson and T. L. Pazdernik. Stress-relatrd protein

response to hypoxia prevent seizure associated brain edema. Soc. Neurosci. Abst. 24: 474.4, 1998.

110. Levant B, Cross RS, Pazdernik TL. Alterations in local cerebral glucose

utilization produced by selective D3 dopamine receptor blockade. Soc. Neurosci. Abst. 24:339.3, 1998

111. Levant B, Pazdernik TL, Cross RS, Shafer RA. Effects of D3 dopamine receptor

stimulation or blockade on neuronal activity in specific brain regions: Fos expression and local cerebral glucose utilization studies. Proc. 37th Ann. Mtg. Am. Coll. Neuropsychopharmacol., 193, 1998.

Curriculum Vitae Thomas Lowell Pazdernik Page 39 112. Pazdernik, T.L., M.R. Emerson, R. Cross, S.R. Nelson and F.E. Samson.

Soman-induced seizures: Limbic activity, Oxidative stress and Neuroprotective proteins. Bioscience Review, Abs. P.68, 1998.

113. Klaidman, L.K., J.D. Adams, R. Cross, T.L. Pazdernik, and F.E. Samson. Nerve

Gas induced brain damage associated with oxidative stress. 4th Annual Meeting of the oxygen Society. Abs# 1-33, 1997.

114. Levant B, Pazdernik TL (2001) Alterations in local cerebral glucose

utilization produced by ibogaine, a putatively anti-addictive drug. Proc 40th Ann. Mtg. Am. Coll. Neuropsychopharmacol.,115.

115. Albright, TJ, Pazdernik, TL, Levant, B (2002) Effects of ibogaine, a

putatively anti-addictive drug, on local cerebral glucose utilization. Experimental Biology, 452.8.

116. Richards TL, Pazdernik TL, Levant B (2002) Differences in quinpirole-

induced local cerebral glucose utilization in naïve and sensitized rats. Soc. Neurosci. Abst. 32:879.19.

117. Levant, B. and T.L. Pazdernik. DIFFERENTIAL EFFECTS OF IBOGAINE

ON LOCAL CEREBRAL GLUCOSE UTILIZATION IN DRUG-NAIVE AND MORPHINE-ADDICTED RATS. Program No. 645.1. 2003 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2003. Online.

118. T.L. Richards, T.L. Pazdernik and B. Levant (2004) Differences in

quinpirole-induced local cerebral glucose utilixation in anterior cortical regions of drug-naïve and quinpirole-sensitized rats. Soc. Neurosci. Abst. 34:803.15.

119. T.L. Richards, T.L. Pazdernik, B. Levant. CLORGYLINE-INDUCED

MODIFICATION OF BEHAVIORAL SENSITIZATION TO QUINPIROLE: EFFECTS ON LOCAL CEREBRAL GLUCOSE UTILIZATION Program No. 681.6. 2005 Abstract. Washington, DC: Society for Neuroscience, 2005. Online.

120. Richards TL, TL Pazdernik and B Levant (2006) Clogyline-induced

modification of sensitization to quinpirole: effects on behavior and local glucose utilization. Exper. Biol. Abst. 434.8.

Book Reviews: 1. T.L. Pazdernik (2003). Review of Progress in Drug Research-Volume 59;

Doody’s Review Service (on-line); available at http://www.doody.com.

Curriculum Vitae Thomas Lowell Pazdernik Page 40 2. T.L. Pazdernik (2003). Review of Appleton & Lange Review of Pharmacology;

Doody’s Review Service (on-line); available at http://www.doody.com. 3. T.L. Pazdernik (2003). Review of Textbook of Receptor Pharmacology;

Doody’s Review Service (on-line); available at http://www.doody.com. 4. T.L. Pazdernik (2003). Review of Introduction to Pharmacology; Doody’s

Review Service (on-line); available at http://www.doody.com. 5. T.L. Pazdernik (2003). Review of Lange Smart Charts; Doody’s Review Service

(on-line); available at http://www.doody.com.

6. T.L. Pazdernik (2003). Review of Oxford Textbook of Clinical Pharmacology and Drug Therapy; Doody’s Review Service (on-line); available at http://www.doody.com.

7. T.L. Pazdernik (2003). Review of Blueprints Notes & Cases: Pharmacology;

Doody’s Review Service (on-line); available at http://www.doody.com. 8. T.L. Pazdernik (2003). Review of Modern Pharmacology with Clinical

Applications; Doody’s Review Service (on-line); available at http://www.doody.com.

9. T.L. Pazdernik (2003). Review of Clinical Pharmacology; Doody’s Review

Service (on-line); available at http://www.doody.com.

10. T.L. Pazdernik (2003). Review of Experimental Therapeutics; Doody’s Review Service (on-line); available at http://www.doody.com.

11. T.L. Pazdernik (2003) Review of Textbook of Receptor Pharmacology, 2nd Ed.;

Shock, Vol 20: 97-98 (2003).

12. T.L. Pazdernik (2003). Review of Cardiac Drug Development Guide; Doody’s Review Service (on-line); available at http://www.doody.com.

13. T.L. Pazdernik (2004). Review of KATZUNG / Basic and Clinical

Pharmacology, 9th Edition. McGraw-Hill Companies, Doody’s Review Service (on-line); available at http://www.doody.com.

14. T.L. Pazdernik (2004). Review of Molecular Neuropharmacology: Strategies and Methods. Humana Press Inc., 2004, Doody’s Review Service (on-line); available at http://www.doody.com.

Curriculum Vitae Thomas Lowell Pazdernik Page 41

15. T.L. Pazdernik (2004). Review of Pharmacology Flash Cards. Lippincott Williams & Wilkins, 2004, Doody’s Review Service (on-line); available at http://www.doody.com.

16. T.L. Pazdernik (2004). Review of MOUSA / Anticoagulants, Antiplatelets and

Thrombolytics. Humana Press Inc., Doody’s Review Service (on-line); available at http://www.doody.com.

17. T.L. Pazdernik (2004). Review of PROKAI / Peptide Transport and Delivery

into the Central Nervous System. Birkhauser, 2003, Springer-Verlag, Doody’s Review Service (on-line); available at http://www.doody.com.

18. T.L. Pazdernik (2004). Review of GOLAN / Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy. Lippincott Williams & Wilkins, 2005, Doody’s Review Service (on-line); available at http://www.doody.com.

19. T.L.Pazdernik (2004). Review of SCHWAIGER / From Morphological Imaging

to Molecular Targeting: Implications for Preclinical Development. Springer-Verlag, 2004, Doody’s Review Service (on-line); available at http://www.doody.com.

20. T.L.Pazdernik (2004). Review of HARMAN / Development and Control of

Medicines and Medical Devices, Pharmaceutical Press, 2004, Doody’s Review Service (on-line); available at http://www.doody.com.

21. T.L.Pazdernik (2004). Review of SHARP / Good Pharmaceutical

Manufacturing Practice: Rationale and Compliance. Taylor & Francis Inc., Imprint: CRC Press I LLC. Doody’s Review Service (on-line); available at http://www.doody.com.

22. T.L.Pazdernik (2004). Review of RAINSFORD / Aspirin and Related Drugs.

Taylor & Francis Inc., Doody’s Review Service (on-line); available at http://www.doody.com.

23. T.L.Pazdernik (2005). Review of MINNEMAN / Brody's Human Pharmacology:

Molecular to Clinical, 4th Edition. Elsevier, Mosby. Doody’s Review Service (on-line); available at http://www.doody.com.

Curriculum Vitae Thomas Lowell Pazdernik Page 42

24. T.L.Pazdernik (2005). Review of TOY / Case Files: Pharmacology. McGraw-Hill Companies, Doody’s Review Service (on-line); available at http://www.doody.com.

25. T.L.Pazdernik (2005). Review of NOGRADY / Medicinal Chemistry: A Molecular and Biochemical Approach, 3rd Edition. Oxford University Press, Inc, 2005, Doody’s Review Service (on-line); available at http://www.doody.com.

26. T.L.Pazdernik (2005). Review of CHO / Annual Review of Pharmacology and

Toxicology 2005. Annual Reviews, 2005, Doody’s Review Service (on-line); available at http://www.doody.com.

27. T.L. Pazdernik (2005) Review of Brody;s Human Pharmacology: Molecular to

Clinical , 4th Ed. Shock, Vol 24: 195 (2005).

28. T.L.Pazdernik (2005). Review of LUELLMANN / Color Atlas of Pharmacology, 3rd Edition. Thieme Medical Publishers, Inc., 2005, , Doody’s Review Service (on-line); available at http://www.doody.com.

29. T.L.Pazdernik (2006). Review of BRUNTON / Goodman & Gilman's The

Pharmacological Basis of Therapeutics Digital Edition, 11th Edition. McGraw-Hill Companies, 2006, Doody’s Review Service (on-line); available at http://www.doody.com.

30. T.L. Pazdernik (2006). Review of RUDIN / Imaging in Drug Discovery and Early

Clinical Trials. Springer, 2005,: Birkhauser. Doody’s Review Service (on-line); available at http://www.doody.com.

31. T.L. Pazdernik (2006). NIJKAMP / Principles of Immunopharmacology, 2nd

Revised Edition. Springer, 2005, Doody’s Review Service (on-line); available at http://www.doody.com.

32. T.L. Pazdernik (2006). Review of VERGNAUD / Assessing Bioavailability of Drug

Delivery Systems: Mathematical Modeling. informa Healthcare/Taylor & Francis, 2005, Doody’s Review Service (on-line); available at http://www.doody.com.

33. T.L. Pazdernik (2006). Review of BRENNER / Pharmacology, 2nd Edition,

Elsevier, 2006, Imprint: Saunders, Doody’s Review Service (on-line); available at http://www.doody.com.

Curriculum Vitae Thomas Lowell Pazdernik Page 43

34. T.L. Pazdernik (2006). Review of CHANGEUX / Nicotinic Acetylcholine Receptors: From Molecular Biology to Cognition. The Johns Hopkins University Press,,Doody’s Review Service (on-line); available at http://www.doody.com.

35. T.L. Pazdernik (2006). Review of RAFFA / Netter's Illustrated Pharmacology;

Elsevier, 2005, Imprint: Saunders. ,Doody’s Review Service (on-line); available at http://www.doody.com.

36. T.L. Pazdernik (2006). Review of IVERSEN / Speed, Ecstasy, Ritalin: The

Science of Amphetamines. Oxford University Press, Inc, 2006; Doody’s Review Service (on-line); available at http://www.doody.com.

37. T.L. Pazdernik (2007). Review of YOUNG / Deja Review: Pharmacology.

McGraw-Hill Companies, 2007, Doody’s Review Service (on-line); available at http://www.doody.com.

38. T.L. Pazdernik (2007). RAMACHANDRAN / Pharmacology Recall, 2nd Edition.

Lippincott Williams & Wilkins, Doody’s Review Service (on-line); available at http://www.doody.com.

39. T.L. Pazdernik (2007). KATZUNG / Basic and Clinical Pharmacology, 10th

Edition. McGraw-Hill Companies, 2007, Doody’s Review Service (on-line); available at http://www.doody.com.

40. T.L. Pazdernik (2007). GREENSTEIN / Concise Clinical Pharmacology.

Pharmaceutical Press, Doody’s Review Service (on-line); available at http://www.doody.com.

41. T.L. Pazdernik (2007). ATKINSON / Principles of Clinical Pharmacology, 2nd

Edition. Elsevier, Doody’s Review Service (on-line); available at http://www.doody.com.

42. T. L Pazdernik (2007). RANG / Rang and Dale's Pharmacology, 6th Edition.

Elsevier, 2007, Doody’s Review Service (on-line); available at http://www.doody.com.

43. T. L Pazdernik (2007). JOHANNSEN / Pharmacards: Review Cards for Medical

Students, 3rd Edition. Lippincott Williams & Wilkins, 2006, Doody’s Review Service (on-line); available at http://www.doody.com.

44. T. L Pazdernik (2007). SIBLEY / Handbook of Contemporary

Neuropharmacology - 3 Volume Set. John Wiley & Sons, Inc., 2007, Doody’s Review Service (on-line); available at http://www.doody.com

Curriculum Vitae Thomas Lowell Pazdernik Page 44

45. T. L Pazdernik (2007). GOLAN / Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, 2nd Edition. Lippincott Williams & Wilkins, 2008, Doody’s Review Service (on-line); available at http://www.doody.com

46. T. L Pazdernik (2008). IVERSEN / The Science of Marijuana, 2nd Edition.

Oxford University Press, Inc, 2008, Doody’s Review Service (on-line); available at http://www.doody.com

47. T. L Pazdernik (2008). TREVOR / Katzung and Trevor's Review of

Pharmacology: Examination and Board Review, 8th Edition. McGraw-Hill Companies, 2008, Doody’s Review Service (on-line); available at http://www.doody.com

48. T. L Pazdernik (2008), EBADI / Desk Reference of Clinical Pharmacology, 2nd

Edition. informa Healthcare/Taylor & Francis, 2008, Imprint: CRC Press I LLC. Doody’s Review Service (on-line); available at http://www.doody.com

49. T. L Pazdernik (2008), WANG / Biomarker Methods in Drug Discovery and Development. Humana Press Inc., 2008, Doody’s Review Service (on-line); available at http://www.doody.com

50. T. L Pazdernik (2008), Farrell / Principles of Pharmacology Workbook, Lippincott Williams & Wilkins, Doody’s Review Service (on-line); available at http://www.doody.com

51. T. L Pazdernik (2008), Brunton / Goodman and Gilman's Manual of Pharmacological Therapeutics, McGraw-Hill Companies, Doody’s Review Service (on-line); available at http://www.doody.com

52. T. L Pazdernik (2008), Jain / Drug Delivery system, Humana Press Inc,, Doody’s Review Service (on-line); available at http://www.doody.com

53. T. L Pazdernik (2008) TOY / Case Files: Pharmacology, 2nd Edition. McGraw-Hill Companies, 2008, Doody’s Review Service (on-line); available at http://www.doody.com

54. T. L Pazdernik (2008) MEYERS / Pharmacology: From Drug Development to Gene Therapy – 2 Volume Set. John Wiley & Sons, Inc., 2008, Doody’s Review Service (on-line); available at http://www.doody.com

Curriculum Vitae Thomas Lowell Pazdernik Page 45

55. T. L Pazdernik (2008), SAHU / Hepatotoxicity: From Genomics to In Vitro and In VivoModels. John Wiley & Sons, Inc., 2007, Doody’s Review Service (on-line); available at http://www.doody.com

56. T. L Pazdernik (2008), RITTER / A Textbook of Clinical Pharmacology and

Therapeutics, 5thEdition. Hodder Arnold, 2008, Distributor: Oxford University Press, Inc. , Doody’s Review Service (on-line); available at http://www.doody.com

57. T. L Pazdernik (2008), BENNETT / Clinical Pharmacology, 10th Edition.

Elsevier, 2008, Imprint: Churchill Livingstone Inc., Doody’s Review Service (on-line); available at http://www.doody.com

58. T. L Pazdernik (2008), KERNS / Drug-Like Properties: Concepts, Structure

Design and Methods from ADME to Toxicity Optimization. Elsevier, 2008, Imprint: Academic Press, Inc., Doody’s Review Service (on-line); available at http://www.doody.com

59. T. L Pazdernik (2008), FINKEL / Lippincott's Illustrated Reviews: Pharmacology,

4th Edition. Lippincott Williams & Wilkins, 2009, Doody’s Review Service (on-line); available at http://www.doody.com.

60. T. L. Pazdernik (2008), Review of: Drug Delivery systems. Shock; Volume 30 -

Issue 3 - p 339.

61. T. L. Pazdernik (2009), BELTING / Macromolecular Drug Delivery: Methods and Protocols. Humana Press Inc., 2009, Doody’s Review Service (on-line); available at http://www.doody.com.

62. T. L. Pazdernik (2009), WALDMAN / Pharmacology and Therapeutics: Principles

to Practice. Elsevier, Imprint: Saunders Doody’s Review Service (on-line); available at http://www.doody.com.

63. T. L. Pazdernik (2009), BRUNTON / Goodman and Gilman's the

Pharmacological Basis of Therapeutics, 11th Edition. McGraw-Hill Companies, 2006, Doody’s Review Service (on-line); available at http://www.doody.com.

64. T. L. Pazdernik (2009), WEISS / High-Yield Pharmacology, 3rd Edition.

Lippincott Williams & Wilkins, 2009, Doody’s Review Service (on-line); available at http://www.doody.com.

65. T. L. Pazdernik (2009), WECKER / Brody's Human Pharmacology: Molecular to

Clinical, 5th Edition. Elsevier, 2009, Doody’s Review Service (on-line); available at http://www.doody.com.

Curriculum Vitae Thomas Lowell Pazdernik Page 46

66. T. L. Pazdernik (2009), BRENNER / Pharmacology, 3rd Edition. Elsevier, 2010, Doody’s Review Service (on-line); available at http://www.doody.com.

67. T. L. Pazdernik (2009), BARON / Lange Pharmacology Flashcards, 2nd Edition.

McGraw-Hill Companies, 2009, Doody’s Review Service (on-line); available at http://www.doody.com.

68. T. L. Pazdernik (2009), KATZUNG / Basic and Clinical Pharmacology, 11th

Edition. McGraw-Hill Companies, 2009, Doody’s Review Service (on-line); available at http://www.doody.com.

69. T. L. Pazdernik (2009) RANDALL / FASTtrack Pharmacology. Pharmaceutical

Press, Publisher of Martindale, 2009, Doody’s Review Service (on-line); available at http://www.doody.com.

70. T. L. Pazdernik (2009, BRENNER / Pharmacology Flash Cards, 2nd Edition.

Elsevier, 2009, Doody’s Review Service (on-line); available at http://www.doody.com.

71. T. L. Pazdernik (2010), SHLAFER / Pharmacology: PreTest Self-Assessment

and Review, 13th Edition. McGraw-Hill Companies, 2010, Doody’s Review Service (on-line); available at http://www.doody.com.

72. T. L. Pazdernik (2010), YALKOWSKY / Handbook of Aqueous Solubility Data,

2nd Edition. CRCPress I LLC, 2010, Doody’s Review Service (on-line); available at http://www.doody.com.

73. T. L. Pazdernik (2010), TREVOR / Katzung and Trevor's Pharmacology:

Examination and Board Review, 9th Edition. McGraw-Hill Companies, 2010, Doody’s Review Service (on-line); available at http://www.doody.com.