TM-OXI AND SUDOPATH STATUS REPORT …ans1test.com/wp-content/uploads/2015/09/TM-OXI-and-SUDOPATH-Report...TM-OXI AND SUDOPATH STATUS REPORT SUMMARY Markers Goal Borderli neAbnormal

Name:

Weight:

Height:

DOB:

Patient Logan Test

280 Lbs

6' " BMI : 37.9

7/30/1981

Gender: Male

Physician

Address:

Referral:

Clinical Context

Physician's notes

7/30/2015 ( ,4 ( :1

TM-OXI AND SUDOPATH STATUS REPORT SUMMARY

Markers Goal Borderli neAbnormal Norms Units Marker of Total Power 1204 >=780 ms2 Overall ANS activity

SDANN 36 >=40 ms Sympathetic activity

RMSSD · 26 >=35 ms Parasympathetic activity

Stress Index 207 <=180 % Sympathetic activity

HF 233 >=220 ms2 Parasympathetic activity

LF/HF 2.1 <=2 Ratio Balance sympathetic/parasympathetic CCDldf"'\ 7'2

ESR L 1.3 <=2 Sec C-Fiber velocity

PeakC 100 >=90 µSi C-Fiber function

SPRV -23 >-40 mm Hg Adrenergic response

DPRS 2 <=5 mm Hg Adrenergic response

SPRS -9 <=10 mm Hg Adrenergic response

Valsalva R. 1.29 >=1.25 Ratio Cardiovagal response

Ell R. 1.21 >=1.20 Ratio Cardiovagal response

K30/15 R. 1.14 >=1.13 Ratio Cardiovagal response

AIPTG 0.43 <=0.45 % Arterial stiffness

-SDda 0.42 <=0.42 Ratio Arterial stiffness

PEPi/LVETi 0.34 <=0.35 Ratio Arterial stiffness

PTGi 39.0 >=40 Vs Arterial marker

PTGVLFi 36 <=33 ms2/µSi Autonomic nerve marker

PT Gr 3.1 <=2.1 Ratio Blood flow marker

Heart Rate 94 <=90 bpm Heart rate average per minute

Sp02 96 >95 % Oxygen saturation level

Systolic P.B 148 <=140 mm Hg Systolic pressure while sitting

Diastolic P.B 89 <=90 mm Hg Diastolic pressure while sitting

Systolic P.S 157 <=140 mm Hg Systolic pressure while standing

Diastolic P.S 87 <=90 mm Hg Diastolic pressure while standing

ANS= Autonomic Nervous System SMR= Sudomotor Response CARTs= Cardiac autonomic reflex tests

DISCLAIMER: This report only displays the results of the ANS1 software, which is based on the assessment of the autonomic nervous system and endothelial function. This report does not replace any conventional diagnosis of diabetes or cardiovascular diseases. It is the physician or referring physician's responsibility to make proper judgments based on these numbers, scores, graphs, comments and suggestions. All results should be considered within the clinical context of the patient's case, history, symptoms, known diagnosis, findings from other diagnostics studies, current medications, treatment plan and therapies.

Patient Name: Logan Test

Weight: 280 Lbs

Height: 6' " BMI: 37.9

DOB: 7/30/1981

Gender: Male

Physician

Address:

Referral:

Clinical Context

Records details PTG partial records images display the ori wave and first and second derivatives.

PTG spectral analysis granhic corresponds established PTGi Pattern Types.

The Analysis images display the_process o evaluating endottielial function, Sudomotor function, and ANS function.

7 /30/2015( .34

TM-OXI AND SUDOPATH STATUS REPORT PARTIAL RECORDS

Photoplethysmograph {PTG) Partial Records

( e 2 • J



Weight: 280 Lbs

Height: 6' .. BMI: 37.9

DOB: 7/30/1981

Gender: Male

Physician

- -

Address:

Referral:

Clinical Context

Physician's Signature

I

7 /30/2011:. _:34

TM-OXI AND SUDOPATH STATUS REPORT COMMENTS

Comments I Suggestions Autonomic Nerve Assessment

ANS Dysfunction: • Description Autonomic Nervous System (ANS} Dysfunction Risk is based on

heart rate variability analysis at rest, and it comprises ANS activity and

balance of the sympathetic and parasympathetic systems.

• Comments/Suggestions Possibility of mental stress. Milrl r,:,rh 1rtinn nf\/n? 1\11:::w Pnc:::cihilih, nf milrl ovorrico intnl.ar:::anro

1v111a sympatnet1c over act1vat1on at rest 1s detected. - -

We suggest to initiate a diet program for losing weight.

Suggested exercise for improving ANS function:

Start slowly and increase the duration and intensity of exercise.

Parasympathetic: • Description Parasympathetic failure risk is based on the analysis of

beat to beat heart rate changes during 3 tests:

Valsalva maneuver, deep breathing and postural change.

• Comments/Suggestions The result is in normal range.

Adrenergic Sympathetic: • Description Adrenergic Sympathetic Failure risk is based on the analysis of

the blood pressure changes during the Valsa lva maneuver

and postu ral change.


Cholinergic Sympathetic: • Description

--

Cholinergic Sympathetic Failure is based on the sweat response to electrica l stimulation at the positive electrode.

The sweat output response is related to the C-Fiber integrity (Peak C), and the time of response is related to

the C-Fiber velocity (ESR L).


ge3


(


Weight: 280 Lbs

Height: 6'" BMI: 37.9

DOB: 7/30/1981

Gender: Male

Physician . .

Address:

Referral:

Clinical Context


I 7 /30/2011.:, _:34


Comments I Suggestions Small Fiber Neuropathy: • Description Small fiber neuropathy risk score uses Sudomotor test (Microcirculation and (-Fiber response) results adjusted with Stress Index,

(marker of sympathetic effect on the peripheral small artery) and PTGi (marker of endothelial function).,

Small Neuropathy Risk Score has a sensitivity of 91.4 % and specificity of 79.1% to detect peripheral neuropathy symptoms,

in diabetic patients (P = 0.0001) . Area under the Roe curve (AUC) =0.858.

• Comments/Suggestions The result is in normal range .

- ... · ·- - - ·- ·-- - ----- - - - -- - . - ---,-• Description Cardiac Autonomic Neuropathy is a risk marker of mortality and cardiovascular morbidity, and possibly

a progression promoter of diabetic nephropathy. In addition, Cardiac Autonomic Neuropathy increases

the risk of hypoglycemia in diabetic patients undergoing treatment.

Cardiac Autonomic neuropathy (CAN) Score uses the same cardiac autonomic reflex tests (CARTs) from the CAN Subcommittee of the Toronto

Consensus Panel on Diabetic N europathy.

• Comments/ Suggestions The result is in normal range.

Arterial Assessment Skin Microcirculation: • Descript ion Skin foot microcirculation risk is based on the sweat response to electrical stimulation at the

negative electrode related to the induced skin hyperemia (ESRNO) .


Arterial Stiffness: • Description Arterial Stiffness is the earliest clinically detectable stage of hypertension.

Arterial Stiffness Score is determined by photoplethysmography analysis.


ge4


(

~ Patient

Name: Logan Test

Weight: 280 Lbs

Height: 6'" BMI: 37.9

DOB: 7/30/1981

Gender: Male

Physician ..

--

Address:

Referral:

Clinical Context


1 /30/201L _:34


Comments I Suggestions High Blood Pressure: • Description Blood Pressure risk is based on calculations from the 3 blood pressure measurements taken during the exam.

• Comments/Suggestions Mild increase of blood pressure resu lts. Weight optimization, increased physical activity and healthy diet is suggested.

If antihypertensive treatment is envisioned ACE or ARBs will be usefu l if no contra indication.

Cardiometabolic Markers Cardiometabolic Risk:

- ---................ .,.!'-''"''""'''

Cardiometabolic Risk (CMR) Score is determined by various markers of the exam.

Click on the bar graph to display the relevant markers.

At 120 minutes, the coefficient of corre lation between the OGTI and CMR Score was: r = 0.56 (p = 0.004)

for glucose, r = 0.53 (p = 0.006) for insu lin, and r = 0.58 (p = 0.002) for (-peptide .

Based on a clinical study comparing diabetes patients to healthy contro ls,

CMR Score had a sensitivity of 91.7% and specificity of 80% as a marker of diabetes.

• Comments/Suggestions Borderline result. Further lab tests (Fasting BG and OGTI) are suggested

PTG Cardiovascular Disease Risk: • Description The PTG CVD Risk is an independent marker of chronic metabolic disease

and cardivascular disease risk. It is based on the homeostatic markers issued from

the PTG spectral ana lysis (PTGi, PTGVLFi and PTGr). Our stud ies

demonstrate that PTGi, PTGVLFi and PTGr are

correlated to endothelial function, autonomic nervous system

function and artery blood flow.

Endothelial dysfunction, autonomic nervous system dysfunction and

artery blood flow are known risk factors for diabetes and atherosclerosis.

Our stud ies showed that PTG CVD Score had a high sensitivity and high

specificity when used to detect coronary artery disease and diabetes.

• Comments/Suggestions Mild homeostatic dysfunction detected. Vascular follow up are suggested.

ge 5

- -


L I . og... 1est 7 /30/2015 12:i

TM-OXI AND SUDOPATH Suggested Lifestyle Control

Page 1

The ANSl exam evaluates the (autonomic) nerves and arteries for dysfunction and damage due to aging and disease. The evaluation represents the body's homeostasis potential expressed as a Homeostatic Score, which is a reflection of the body's ability to adapt to the environment and potential to avoid disease. Disease occurs when the body's homeostasis potential is overburdened, and this is reflected by showing a very low score. Improved lifestyle management (weight control, diet, exercise, stress reduction, sleep, no smoking, reduction or elimination of alcohol consumption) is an effective means to increase one's homeostasis score, which will help delay the aging process, help prevent the onset of cardio metabolic diseases and complications, and is a significant part of the treatment plan for diabetes and cardiovascular disease.

I . -··~ Weight Classification And Follow Up I Your BMI is: 37.9 Kg/m2

Your Fat Mass is: 47 %

Your Activity Level is: Moderate: Walk 20 Minutes A Day Or 2 Hours Of Sport A Week

Regarding the International Classification of adult* underweight, overweight and obesity according to BMI You are overweight and classified as Obese Class II. Obesity is now considered as a disease *Source: Adapted from WHO, 1995, WHO, 2000 and WHO 2004.

BMI follow up

L ( .

og.. ,est 7 /30/2015 12:J..


Page 2

I Calories Control I

The number of calories consumed will varv bv individual based on ae:e. e:ender. heie:ht_ wpight ;:incl lifP,tvlP _ La\...11 1-1c• ::>u,, 11a::> a oa::>a1 1v1eLduu111... l"\dLe ,o,vmJ w111cr1 represen1s 1ne minimum ca1ories requ1rea ror aa11y normal body functions. It is not safe to reduce your BMR, even if you are undergoing a diet program to lose weight.

Your Basal Metabolic Rate is (BMR) = 2492 Calories

In order to maintain your weight, we calculate your Daily Energy Expenditure (DEE) according to your weight and your activity level.

Your Daily Energy Expenditure is (DEE) = 3863 Calories

If you wish to lose weight, you have to decrease the number of calories of your DEE or increase your activity level.

( Log~ rest

~

7 /30/2015 12:~.


Page 3

I Glycemic Index Control I

The appropriate amount of carbohydrates in foods which directly raise blood glucose should hi:> nf rnnri:>rn fnr rli::i hot i re

I ne suggested amount ot carbohydrates may be determined by factors like age, gender, activity level, and blood glucose control goals. About 45-60 grams per meal is suggested generally for adults.

> Avoid foods high in sugar and try to estimate the amount of carbohydrates in your daily diet to your best ability. > Choose a low Glycemic Index (GI) diet which promotes reduced fluctuations in blood glucose. > The Glycemic Index (GI) is a numerical index that reveals the effects of carbohydrates on blood

glucose levels on a scale of Oto 100. Choosing lower GI foods that promote reduced fluctuations in blood glucose is recommended for long-term blood glucose control. Foods with low GI include all non-starchy vegetables and some starchy vegetables, most fruit, beans and legumes (e.g., kidney beans and lentils), and many whole grain breads and cereals (e.g., whole wheat bread and all-bran cereal). Meats and fats have a GI score of O because they do not contain carbohydrates.

GI Examples Of Foods

High {70 and above)

Medium (56 to 69)

Low (55 and under)

White bread, most white rice, corn flakes, extruded breakfast cereals, glucose, maltose ...

Whole wheat products, basmati rice, sweet potato, sucrose, baked potatoes ...

Most fruits and vegetables, legumes/pulses, whole grains, nuts, fructose and products low in carbohydrates ...

LoJ ... j·est 7 /30/2015 12:f


Page 4 (

I ~······- ··. Dietary Supplements ~]

In the case of dietary supplements, the main risks for diabetics are hypoglycemia, the potential adverse reactions to anti-diabetic drugs, and the uncertain long-term

safety. Clinicians should be aware of their patients' use of such products, and should inform them about whether the benefits have been scientifically confirmed. In 2013, the National Center for Complementary and Alternative Medicine (NCCAM) stated that there is not enough scientific evidence to suggest th;it ;inv cfo=~t;irv

... _... ........ . .............. . ........................... ,.., t-'' .... v '- 1 I I. ....,, 111c11105c UICUCLC.:>, LIICLal y .:,UtJ(Jlt'I I lt'l ll::) ::,11uu1u ue U!:>eO unaer mea1ca1 superv1s1on.

Avocado Avocadoes are rich in monounsaturated fats and soluble fibers that improve insulin sensitivity and reverse insulin resistance.

Cherry Cherries contain red pigmented antioxidants, are low in calories, and rich in soluble fibers that can improve the body' s insulin output.

Cinnamon Cinnamon contains magnesium, fibers and polyphenols, which possibly mimic the effect of insulin and can significantly lower blood glucose level.

Flaxseed Flaxseeds are rich in fiber and Omega-3 fatty acids, and low in carbohydrates and fat which help lower blood glucose and cholesterol levels. They are also strongly anti-inflammatory.

Garlic Garlic contains high levels of anti-oxidants. It has been proven that garlic can raise insulin production and lower blood glucose.

Lemon Lemons are rich in vitamin C, rutin, limonene, and low on the glycemic index scale which help prevent high blood glucose

Lo( rest 1 /30/201s 12:L


Page 5

I Dietary Supplements -1

Nuts N11t, ;:irp rirh in onnrl f::itc ::inrl nrntoinc ~nrl c,ro nrn\/on +n h-."" .... '"''"''";+;.,~ ~,,~-+ ~~

msu11n proauct1on which lowers the risk ot developing type 2 diabetes. Examples of healthy nuts are almonds, cashews, peanuts, pecans and walnuts, etc.

Onion Onions contain high level of sulfur and flavonoid which significantly help lower blood glucose level and raise good cholesterol (HDL) level. They are also strongly antiinflammatory as well as diuretic to help lower blood pressure.

Sweet Potato Sweet potatoes contain rich soluble fibers that have excellent effects on regulating insulin and lowering cholesterol. They have a medium GI which prevent high blood glucose fluctuation, and they are also rich in anti-oxidants, beta carotene, vitamin A and 86. High level of Vitamin 86 found in sweet potatoes is believed to help reduce the risk of diabetic heart disease.

Vinegar Vinegar has been shown in studies to help lower both fasting and after-meal glucose levels. Drinking two to three tablespoons or adding two to three tablespoons to you meal per day is recommended for improved blood glucose control.

Fiber It's the indigestible part of plant foods so that it can almost be subtracted for carbohydrate counting. Recent study indicated that fiber contributes to blood glucose control. Vegetables, fruits, whole grains nuts and legumes are rich in fibers which prevent stomach irritation and constipation.

L ( .

og .. __ 1est I

7 /30/2015 12:3 ...


Page 6

I Dietary Supplements I

Chromium Picolinate rhr-/""\mi11m ic ':l,r'\ .CH'"t'."C\l•"\+i""\I t"V'\in,..,. .... -..1 "'""··-rJ :- ,..,._L,.... ~--,J,.. ...... ,.. ••• L.-1- ---=-- --- .. . -11 ... - ----' L-----•= A ----.&..- ----.L=-

review and meta-analysis of 25 RCTs concluded that there is now enough evidence to suggest that chromium mono-supplementation has favorable effects on glycemic control in diabetic patients.

Ginseng 12-week daily supplementation with 5-g red ginseng decreased serum and whole blood levels of glucose, and tended to reduce serum insulin and (-peptide concentrations in persons with IFG, impaired glucose tolerance, or newly diagnosed T2D.

Fish Oil Because of its ability to lower triglyceride levels and the risk for arrhythmia, fish oil-and more specifically omega-3 polyunsaturated fatty acids (PUFAs)-may be used by diabetic patients.

Aloe Vera Aloe vera, it could help to reduce body weight, body fat mass, and insulin resistance in obese individua Is with prediabetes or early untreated diabetes mellitus, according to a recent trial.

LoL rest 7 /30/2015 12:~-


Page 7

I Not recommended food ( High GI) I Carbohydrate in foods raises blood glucose level directly so that the amount should be restr icted for achieving the goa I of glycemic control. The three main types are:

Starches Starchy vegetables: include peas, corn, lima beans and potatoes

Grains Include whole grain (recommended for healthy diet) and refined grain: such as barley, bran and rice.

Sugar Naturally occurring sugars: such as those in milk or fruit Added sugar: those added during processing such as cakes, cookies, donuts and beverages.

:-..

I Log~ rest

I

7 /30/2015 12:3 .....


Page 8

I Benifits Of Exercise I > The intensity, frequency and duration of physica l activity will vary for each individual, but being active is very important to one's overall health. Exercise produces positive effects on the body that prevent chronic diseases such as high blood pressure, and help body weight control. 0\, h o inrT -. ...... +;,,,.... ,,_,,,II ............ + ......... I . . L-.. ..... 1 ...... ---··--.&.. -L ----=- --.1: _____ L .. ...... - • - __ 1 _

and help strengthen and improve your muscles and bones.

Activities Examples Effects

Moderate intensity aerobic

Vigorous intensity aerobic

Stretching

Muscle - strengthening

Bone - strengthening

TUE

WED

THU

SAT

SUN

Hiking, bicycle riding

Running, swimming

Yoga, Pilates, Tai chi

Push-ups, sit-ups

Enhance cardiopu Imo nary function

Improves flexibility

Jumping rope, gymnastics, Sports such as basketball, volleyball, tennis

Enhance muscle strength, muscular endurance and bone strength

Examples of activity plan in one week Jumping rope 10 min+ jogging 20 min (aerobic)

Bicycle riding 30 min (aerobic)

Yoga 40 min (aerobic, stretching)

Swimming 40 min (aerobic, weight training)

Boxing aerobic 30 min (aerobic, stretching)

Lo{ ,est 7 /30/2015 12:d.


Page 9

I ~ Blood Pressure Control I Lifestyle changes can help you control and prevent high blood pressure - even if you're taking blood pressure medication. Here's what you can do:

1:at nea1tny rooas. Try the Dietary Approaches to Stop Hypertension (DASH) diet, which emphasizes fruits, vegetables, whole grains and low-fat dairy foods . Get plenty of potassium, which can help prevent and control high blood pressure. Eat less saturated fat and total fat.

Decrease the salt in your diet. A lower sodium level - 1,500 milligrams (mg) a day - is appropriate for people 51 years of age or older, and individuals of any age who are African-American or who have hypertension, diabetes or chronic kidney disease. Otherwise healthy people can aim for 2,300 mg a day or less. While you can reduce the amount of salt you eat by putting down the saltshaker, you should also pay attention to the amount of salt that's in the processed foods you eat, such as canned soups or frozen dinners.

Maintain a healthy weight. If you're overweight, losing even 5 pounds (2.3 kilograms) can lower your blood pressure

Increase physical activity. Regular physical activity can help lower your blood pressure and keep your weight under control. Strive for at least 30 minutes of physical activity a day.

Limit alcohol. Even if you're healthy, alcohol can raise your blood pressure. If you choose to drink alcohol, do so in moderation - up to one drink a day for women and everyone older than age 65, and two drinks a day for men.

( Lot, . . Test 1 /301201s 12L_


Page 10

I ·~ Blood Pressure Control I Don't smoke Tobacco injures blood vessel walls and speeds up the process of hardening of the arteries." If you smoke, ask your doctor to help you quit.

Manage stress. Reduce stress as much as possible. Practice healthy coping techniques, such as muscle relaxation and deep breathing. Getting plenty of sleep can help, too.

Monitor your blood pressure at home. Home blood pressure monitoring can help you keep closer tabs on your blood pressure, show if medication is working, and even alert you and your doctor to potential complications. If your blood pressure is under control, you may be able to make fewer visits to your doctor if you monitor your blood pressure at home.

Practice relaxation or slow, deep breathing. Practice taking deep, slow breaths to help relax. There are some devices available that can help guide your breathing for relaxation; however, it's questionable whether these devices have a significant effect on lowering your blood pressure.

0,

,,

Documents

TM-OXI AND SUDOPATH STATUS REPORT …ans1test.com/wp-content/uploads/2015/09/TM-OXI-and-SUDOPATH-Report...TM-OXI AND SUDOPATH STATUS REPORT SUMMARY Markers Goal Borderli neAbnormal