1 Electronic Supporting Information Total Synthesis of a Potent Hybrid of the Anticancer Natural Products Dictyostatin and Discodermolide Ian Paterson,* a Guy J. Naylor a and Amy E. Wright b a University Chemical Laboratory, Lensfield Road, Cambridge, CB2 1EW, United Kingdom, b Harbour Branch Oceanographic Institution at Florida Atlantic University, 5600 US 1 North, Ft. Pierce, FL 34946, USA 1 H and 13 C NMR Data for Compounds 13 – 15 and 3 Supplementary Material (ESI) for Chemical Communications This journal is (c) The Royal Society of Chemistry 2008

Total Synthesis of a Potent Hybrid of the Anticancer Natural ...1 Electronic Supporting Information Total Synthesis of a Potent Hybrid of the Anticancer Natural Products Dictyostatin

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Electronic Supporting Information

Total Synthesis of a Potent Hybrid of the Anticancer Natural

Products Dictyostatin and Discodermolide

Ian Paterson,*a Guy J. Naylora and Amy E. Wrightb

a University Chemical Laboratory, Lensfield Road, Cambridge, CB2 1EW, United

Kingdom, b Harbour Branch Oceanographic Institution at Florida Atlantic

University, 5600 US 1 North, Ft. Pierce, FL 34946, USA

1H and 13C NMR Data for Compounds 13 – 15 and 3

Supplementary Material (ESI) for Chemical CommunicationsThis journal is (c) The Royal Society of Chemistry 2008
2

Supplementary Material (ESI) for Chemical CommunicationsThis journal is (c) The Royal Society of Chemistry 2008
3

Supplementary Material (ESI) for Chemical CommunicationsThis journal is (c) The Royal Society of Chemistry 2008
4

Supplementary Material (ESI) for Chemical CommunicationsThis journal is (c) The Royal Society of Chemistry 2008
5

Supplementary Material (ESI) for Chemical CommunicationsThis journal is (c) The Royal Society of Chemistry 2008
6

Supplementary Material (ESI) for Chemical CommunicationsThis journal is (c) The Royal Society of Chemistry 2008
7

Supplementary Material (ESI) for Chemical CommunicationsThis journal is (c) The Royal Society of Chemistry 2008
8

Supplementary Material (ESI) for Chemical CommunicationsThis journal is (c) The Royal Society of Chemistry 2008
9

Supplementary Material (ESI) for Chemical CommunicationsThis journal is (c) The Royal Society of Chemistry 2008
10

Supplementary Material (ESI) for Chemical CommunicationsThis journal is (c) The Royal Society of Chemistry 2008
11

Supplementary Material (ESI) for Chemical CommunicationsThis journal is (c) The Royal Society of Chemistry 2008
12

Supplementary Material (ESI) for Chemical CommunicationsThis journal is (c) The Royal Society of Chemistry 2008
13

Supplementary Material (ESI) for Chemical CommunicationsThis journal is (c) The Royal Society of Chemistry 2008
14

Supplementary Material (ESI) for Chemical CommunicationsThis journal is (c) The Royal Society of Chemistry 2008
15

Supplementary Material (ESI) for Chemical CommunicationsThis journal is (c) The Royal Society of Chemistry 2008
16

Supplementary Material (ESI) for Chemical CommunicationsThis journal is (c) The Royal Society of Chemistry 2008
17

Supplementary Material (ESI) for Chemical CommunicationsThis journal is (c) The Royal Society of Chemistry 2008
18

Supplementary Material (ESI) for Chemical CommunicationsThis journal is (c) The Royal Society of Chemistry 2008