Toward the global cooperation:

Global Catalogue of Microorganisms

Dr. Juncai MA

World Data Center for Microorganisms(WDCM)

Institute of Microbiology, Chinese Academy of Sciences

Beijing, April 4, 2013

Microbial Resources Centres Mircen UNESCO

United Nations Educational, Scientific and Cultural Organization

International Union of Biological Sciences

The International Union of Microbiological Societies

World Federation for Culture Collections

MICROBIAL

RESOURCES

CENTRES MIRCEN

UNESCO

By March 30, 2013

640 culture collections from 72 countries

World Federation of Culture Collections

Development of WDCM

Prof. V. B. D.

Skerman

Prof. Kazuo Komagata

Prof. Hideaki Sugawara

Dr. Juncai Ma

1966

the University of Queensland

1986

RIKEN in Japan

1997

the National Institute of Genetics in

Japan

2010

Institute of Microbiology, CAS in China

The 1st generation The 2nd generation The 3rd generation

1. Nov 2011- Dec 2012: Pilot phase

Plan to have 20-30 volunteer Collections

2. Jan 2013 - :

Welcome all collections worldwide

WFCC Global Catalogue of Microorganisms (GCM)

More than 100 CCs

in 2014

WDCM MDS is composed of 15 fields. The input files could

be either EXCEL or XML.

Publications explored by Analyzer of Bio-resources Citations(ABC)

Detailed information of Strains Catalogue information from collections

Link back to original site

Sequences explored by ABC

Detailed information of Strains Patents explored by ABC

Choose sequences to execute bioinformatics analysis

Online exchange strains between CCs

Link out to CCINFO database

List of culture collections in the search result

Display the table of isolation sources

Display the Geographic origin of strains

Exploring information about a species

Publication information about the species

Patents

Phylogenetic analysis

Multiple Sequence Alignment

Species Identification

Strain sequence database

Blast tools

Taxonomy information

Advanced search interface

Searching strains by publications and patents

Searching results by publications and patents

WFCC Global Catalogue of Microorganisms (GCM)

GCM is not just a simple integrated

catalogue,

but also a information service platform

for culture collections worldwide

Analyzer of Bio-resources Citation

How many Papers, Patents, Sequences, Genomes are

published worldwide using my microbial strains?

BRCs distribute many microbial strains per year.

It is our great contributions from WFCC collections.

-- An data mining tools to trace and explore utilization of microbes

Data Mining of 3005 journals from 1953 – 2012:

172,123 papers cite 123,681 strains in 415 Culture Collects of 66 country.

12,349 patents descript 15,618 strains in 185 Culture Collects of 54 country.

747,786 sequences are from 63,406 strains in 249 Culture Collects of 55 country.

Result of RIKEN BRC/JCM

Paper

Patents

Analyzer of Bio-resource Citation

User can upload paper information and PDF document which is related to his/her culture collection.

Upload your own papers

Vietnam Type Culture Collection

1,000 strains

Choose data items according to your own catalogue items

Import your data in EXCEL file

Export an EXCEL template for data management

http://gcm.wfcc.info/cc/vtcc

Android version of Global Catalogue

iPAD version will be Available soon

国际标准化组织 ISO (International Organization for Standardization)

112

46

4

• ISO covers 162 countries and areas.

• Up to now, ISO developed 19,500 standards, 3,958 are in biological field.

• 350,000 companies are using ISO standards.

Contents Page

Foreword iv

Introduction v

1. Scope 1

2. Normative reference 1

3. Terms and definitions 1

4. Principle 2

5. Safety precaution 2

6. Reference fungi 3

7. Apparatus 3

8. Reagents and culture media 5

9. Fungus preservation and use 8

10. Spore suspension 9

11. Preparing ATP calibration curve 12

12. Testing method 13

13. Measurement of luminescence

intensity 15

14. Calculation 17

15. Test report 18

Annex A 19

Annex B 20

Bibliography 21

Antifungal activity testing method

ISO/FDIS 13629-1

ISO/FDIS 13629-1 Antifungal activity testing method

WDCM number Species Preservation No.

00144 Aspergillus niger

ATCC 6275 UMIP 2475.98 DSM 1957 NBRC 105649

00189 Penicillium citrinum ATCC 9849 NBRC 6352

00190 Cladosporium cladosporioides

ATCC 11277 NBRC 6368 NBRC 6348

00191 Trichophyton mentagrophytes

NBRC 32409 NBRC 32412

The utilization of WDCM reference strains according to ISO standards

count total

Food manufacture and security 25 Milk and milk products 55 157 Microbiology of food and animal feeding stuffs 77 Biological evaluation of medical devices 2 Dentistry 1 Washer-disinfectors 12 Sterilization of health care products 26 Surgical drapes, gowns and clean air suits, used as medical devices 6 99 Retrieval and analysis of surgical implants 1 Optics and optical instrument 10 Medical laboratories 5 Clinical laboratory testing and in vitro diagnostic test systems 28 Modification of the isolation media and the haemolysis test 6 Cleanrooms and associated controlled environments 2 Water quality 57 57 Textiles 10 Lubricants, industrial oils and related products 3 Chemical analysis of refractory products by XRF 1 32 Plastics 17 Safety of machinery 1 Cosmetics 22 22 Indoor air 11 Soil quality 4 15

26%

4% 41%

15%

8% 6%

medical devices and health

environments

Foodstuffs

Water quality

industrial production

Cosmetics

WDCM Reference Strain Catalogue

Cooperation

with Regional/National Networks

Cooperation with EMbaRC

EMbaRC CCs join GCM together

WDCM develop EMbaRC catalogue page

EMbaRC homepage links EMbaRC

catalogue in GCM

European Consortium of Microbial Resources Centres

(EMbaRC)

Cooperation with Russia collections

Jointly develop data standards

WDCM provide data platform

Join GCM

MOU with BIOTEC, Thailand September 14, 2011

WDCM Symposiums

and Training Course

The First WDCM Symposium May 17-18, 2011, Beijing

The Second WDCM Symposium June 7-8, 2012, Beijing

WDCM Asian Training Course on Management and Application of Microbial Data

May 27 –June 6,2012, Beijing, China

Hosted By:

WFCC-MIRCEN World Data Center for Microorganisms (WDCM)

Organized By:

World Federation for Culture Collections (WFCC)

United Nations Educational, Scientific and Cultural Organization(UNESCO)

Asian Consortium for Conservation and Sustainable Use of Microbial Resources (ACM)

Asian Network for Research Resource Centers(ANRRC)

Biological Resources Center, Institute of Microbiology, CAS(IMCAS)

Research Network for Applied Microbiology, Chinese Academy of Sciences (RNAM)

Supported By:

Bureau of International Cooperation, Chinese Academy of Sciences(BICCAS)

China National Committee, the Committee on Data for Science and Technology (CODATA)

WDCM Symposiums and Training Course every year

19 trainees from 8 countries

14 teachers from 5 countries

86 scientists from 70 institution/universities of 25 countries

Chinese DB for DNA Barcode of Life

Participants 中国科学院动物研究所 中国医学科学院药用植物研究所

中国科学院植物研究所 江西农业大学

中国科学院微生物研究所 中国科学院应用生态所

中国科学院昆明动物研究所 西北农林科技大学

中国科学院昆明植物研究所 中国科学院成都生物所

中国科学院华南植物园 东北林业大学

兰州大学 四川大学

中国科学院西双版纳园 中国科学院庐山植物园

中国科学院武汉植物园 中国科学院水生生物研究所

浙江大学 中国检验检疫科学研究院

CAS institutions：12 Universities and others：8

WFCC president and board Members

42 collections in GCM

Asian Consortium for Conservation and Sustainable Use of Microbial

Resources (ACM)

Asian Network for Research Resource Centers(ANRRC)

European Consortium of Microbial Resources Centres (EMbaRC)

Acknowledgement

My Team

马俊才 博士 刘澎涛

劳一美

吴林寰 硕士

杜晓萌 刘全贺

刘翟 博士

陈 成

Full time staffs：

田园静

孙清岚 硕士

李聚敏 杨 松

庞菊梅 硕士 刘力 博士

彭 程 丁 慧

王攀登

李伟 硕士

Students

夏 青 苏小林 张 润 魏永勇 吴 军

王楠 硕士

苏锦河