Tracy George 1

March 1, 2016

Tracy I. George, M.D.

Professional Address:

Mailing address:

Department of Pathology

MSC 08-4640

University of New Mexico School of Medicine

1 University of New Mexico

Albuquerque, NM 87131-0001

TriCore Reference Laboratory

1001 Woodward Place NE

Albuquerque, NM 87102

Phone: 505-938-8243

FAX: 505-938-8414

Licensures:

05/1997-08/2016 Physician & Surgeon, The Medical Board of California, A62223

03/2001-10/2014 DEA License, BG7189423

11/2011-06/2015 Active Status Medical Doctor, Nevada State Board of Medical

Examiners, 14173

12/2012-09/2016 Licensed Physician, New Mexico Medical Board, MD2012-0889

01/2013-01/2018 Medical Doctor, State of Florida, ME 118408

1/14/2015-08/2016 Licensed Physician, Louisiana State Board of Medical Examiners,

MD.207588

Board Certification:

09/2000-unlimited Diplomate, The American Board of Pathology, Anatomic & Clinical

Pathology

01/2014-01/2024 Recertification, The American Board of Pathology, AP/CP

10/2001-unlimited Diplomate, The American Board of Pathology, Hematology (Pathology)

03/2009-03/2013 New York State Department of Health, Certificate of Qualification,

Laboratory Director in Hematology, CQ Code: GEORT5

Educational History:

06/1995 M.D., University of California San Francisco School of Medicine,

San Francisco, California

05/1990 B.A., with High Distinction (Molecular Biology),

University of California Berkeley, Berkeley, California

Employment History:

Tracy George 2

Residency and Fellowship Training-

07/2000-06/2001 Fellowship, Hematopathology, Stanford University School of Medicine,

Stanford, California

07/1999-06/2000 Residency, Pathology and Laboratory Medicine, University of California

San Francisco, School of Medicine, San Francisco, California; including

Chief Resident in Laboratory Medicine

07/1998-06/1999 Fellowship, Surgical Pathology, Stanford University School of Medicine,

Stanford, California

07/1995-06/1998 Residency, Pathology and Laboratory Medicine, University of California

San Francisco School of Medicine, San Francisco, California

including Chief Resident, Pathology at San Francisco General Hospital

from 01/1998-03/1998

Employment History:

01/2013 - present Associate Professor of Pathology

Chief, Hematopathology Division

Hematopathology Fellowship Program Director

University of New Mexico Health Sciences Center and

TriCore Reference Laboratories

Albuquerque, New Mexico

11/2012 – 12/2012 Associate Professor of Pathology

Stanford University School of Medicine

Stanford, California

06/2012 – 12/2012 Interim Associate Director of Pediatrics, Anatomic Pathology and Clinical

Laboratories, Lucile Packard Children’s Hospital

08/2005 – 10/2012 Assistant Professor of Pathology

Stanford University School of Medicine

Stanford, California 09/2004 – 07/2005 Clinical Assistant Professor of Pathology

Stanford University School of Medicine

Stanford, California

09/2002 – 08/2004 Clinical Instructor of Pathology

Stanford University School of Medicine

Stanford, California

08/2001 – 06/2002 Pathologist, Central Coast Pathology Consultants, San Luis Obispo, CA

Marian Medical Center, Santa Maria, CA

Sierra Vista Regional Medical Center, San Luis Obispo, CA

French Hospital Medical Center, San Luis Obispo, CA

Twin Cities Community Hospital, Templeton, CA

Arroyo Grande Community Hospital, Arroyo Grande, CA

Employment History (Research Fellowships):

10/2007 – 01/2008 Sabbatical, The Nuffield Department of Clinical Laboratory

Sciences Pathology, Oxford University, John Radcliffe Hospital

with Professor David Mason, M.D. and Teresa Marafioti, M.D.

7/1992 – 6/1993 American Heart Association Medical Student Research Fellowship

Tracy George 3

Advisor: Maria G. Pallavicini, Ph.D.

University of California, San Francisco

Department of Laboratory Medicine, Division of Molecular Cytometry

Stem Cells in Acute Myeloid Leukemia & Myelodysplasia

6/1990 - 8/1990 University of California San Francisco, Dean's Research Fellowship

Advisor: Frederic Waldman, M.D., Ph.D.

University of California, San Francisco

Department of Laboratory Medicine, Division of Molecular Cytometry

Genetic Aberrations in Bladder Cancer Measured by Fluorescent In Situ

Hybridization

6/1989 – 8/1989 Associated Western Universities Undergraduate Honors Student

6/1988 - 8/1988 Fellowship, Advisor: Maria G. Pallavicini, Ph.D.

6/1987 – 8/1987 Lawrence Livermore National Laboratory, Biomedical Division

Detection of c-myc mRNA in Cells by Fluorescent In Situ Hybridization

Discrimination of Cell Types in Mouse Bone Marrow using Flow

Cytometric Analyses

Professional recognition, honors:

2015 Leadership Development for Physicians in Academic Health Centers,

Harvard School of Public Health, October 11-23, 2015, Boston, MA

2014 College of American Pathologists Lifetime Achievement Award

2011 Excellence in Teaching, Stanford University School of Medicine

2010 Excellence in Teaching, Stanford University School of Medicine

2008 Excellence in Teaching, Stanford University School of Medicine

2006 Stanford University Faculty Fellows Program, a leadership development

program

2006 AAMC Early Career Women Faculty Professional Development Seminar

July 8-12, 2006, Washington, DC

1990 Honor Students Society, and scholarship, U.C. Berkeley

1990 Golden Key National Honor Society, U.C. Berkeley

1990 Highest Honors, U.C. Berkeley

1989 Phi Beta Kappa, U.C. Berkeley

1989 Prytanean, U.C. Berkeley Women’s Honor Society

1989 Prytanean Prize, volunteer and service to the campus and community

1989 Kappa Alpha Theta Founders' Memorial Scholar, one of 4 women

selected nationally in recognition of scholarship, sorority, and

community activities

1989 Mortar Board Honor Society U.C. Berkeley

1986-1990 Dean's List, 4 semesters U.C. Berkeley

1986-1990 Undergraduate Scholarships, University of California, Berkeley

1986-1990 California Alumni Scholar and recipient of 2 alumni scholarships, U.C.

Berkeley

Memberships in Professional Societies:

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2013 - present Member, Bone Marrow Pathology Group, USA

2011 - 2012 International Council for Standardization in Haematology

2009 - present Member, European Bone Marrow Working Group

2008 - 2012 Member, South Bay Pathology Society

2004 - 2014 Member, Association for Molecular Pathology

2004 - 2012 Member, Clinical Cytometry Society

2003 - present Society for Hematopathology

2002 - present International Society of Laboratory Hematology

2001 - present American Society of Hematology

1996 - present American Society of Clinical Pathologists

1996 - present College of American Pathologists

1996 - present United States and Canadian Academy of Pathology

1996 - 2012 Member, University of California San Francisco Alumni Association

1995 - 1996 Member, California Medical Association

1994 - 1997 Member, National Organization for Women

1993 - 1995, 2004 - 2006 Member, International Society of Analytical Cytology

1991 - 1996 Member, American Medical Women's Association

1990 - 2004 Member, California Alumni Association

1988 - present Member, Prytanean

1987 - present Member, Kappa Alpha Theta

Other extramural professional activities

2015 - 2017 Contributing Editor, The Hematologist

2013- present Associate Editor, International Journal of Laboratory Hematology

2014 Guest Editor, International Journal for Laboratory Hematology,

Educational Issue

2013 Guest Editor, International Journal for Laboratory Hematology,

Educational Issue

2013 Guest Editor, Surgical Pathology Clinics

2010 – 2013, 2015 Editorial Board, American Journal of Clinical Pathology

2007 - present Editorial Board, International Journal of Laboratory Hematology

Ad hoc reviewer Applied Immunohistochemistry and Molecular Morphology

Archives of Pathology & Laboratory Medicine

Blood

European Journal of Clinical Investigation

European Journal of Haematology

Histopathology

Human Pathology

International Archives of Allergy and Immunology

Journal of Clinical Pathology

Lab Medicine

Leukemia Lymphoma

Modern Pathology

Molecular Oncology

The American Board of Pathology

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1/2013- 12/2015 Test Development and Advisory Committee on Hematology

American Society of Clinical Pathologists

12/2014 – 12/2015 Chair, Steering Committee, The Diagnosis, Classification and

Clinical Care of MDS II (DC3-MDS)

American Society of Hematology

6/2014 - present Member, Image Bank Task Force

College of American Pathologists

2014 - 2019 Guideline Metrics Expert Panel, Acute Leukemia

1/2014 - 12/2014 Member, Quality Practices Committee

1/2013 - 12/2013 Advisor, Hematology & Clinical Microscopy Resource Committee

1/2010 - 12/2014 Member, Council on Scientific Affairs

1/2009 - 12/2012 Chair, Hematology & Clinical Microscopy Resource Committee

1/2008 - 12/2009 Member, Ad Hoc Committee for Center Plan Development

1/2007 - 12/2008 Vice Chair, Hematology & Clinical Microscopy Resource

Committee

1/2005 - 12/2007 Member, Hematology & Clinical Microscopy Resource Committee

1/1997 - 12/1997 Member, Government Affairs Committee

International Society of Laboratory Hematology

5/2015 – 5/2018 Vice President of Scientific Communications

5/2015 – 5/2018 Program Director, ISLH Annual Meeting

5/2015 – 5/2016 Vice-Chair, Cellular Analysis Scientific Committee

5/2014 - 5/2015 Executive Secretary

5/2014 - 5/2015 Program Co-chair, ISLH 2015, Chicago, IL

5/2011 - 5/2014 Director of the Board

2014 Program Committee, Abstract Committee, ISLH 2014, The Hague,

Netherlands

2013 Program Committee, Abstract Committee, ISLH 2013, Toronto,

Canada

2012 Program Committee, ISLH 2012, Nice, France

2011 Program Committee, ISLH 2011, New Orleans, LA

The Mastocytosis Society

11/2015-11/2018 Medical Advisory Board

Society for Hematopathology

2014 - 2017 Membership Committee

United States and Canadian Academy of Pathology

2016 - 2018 Moderator, Coordinator, Hematopathology Specialty Conference

2014 Abstract Review Board, Hematopathology

2011 Moderator, Hematopathology Scientific Session

2005 Moderator, Hematopathology Scientific Session

2008 - present Scientific advisor, Cellscape

2008 - 2017 Member, Steering Committee for Study CPKC412D2201, Novartis, Inc.

2009 - 2011 Nplate Safety Registry Advisory Committee, Amgen

2011 Invited participant, Morphology Workshop, New Orleans, LA,

International Council for Standardization in Haematology

2012 Faculty, BWH Mastocytosis Center Symposium on Mastocytosis

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2012 Participant, Consensus meeting on diagnostic criteria and classification of

mastocytosis

2014 - 2016 Member, Celgene Scientific Steering Committee, AML/MDS Registry

2014 - 2016 Member, Incyte Hematopathology Publications Committee

Invited Lectures (61 total, 5 pending):

2002,“Biology of Cancer.” California Polytechnic Institute, San Luis Obispo, CA

2002,“Updates in Flow Cytometry.” Marian Medical Center, Santa Maria, CA

2002,“Updates in Flow Cytometry.” Twin Cities Regional Medical Center, Templeton, CA,

2003, “Principles & Practice of Flow Cytometry, Implications for Clinical Diagnosis.”

California Association for Medical Laboratory Technology, San Luis Obispo Chapter,

Annual Meeting, Sierra Vista Medical Center, San Luis Obispo, CA

2005,“Case studies in Myeloproliferative Diseases.” California Association for Medical

Laboratory Technology, Annual Meeting & Workshops, Santa Clara Convention Center,

Santa Clara, CA

2006,“Lack of expression of PDGFRb in Langerhans cell histiocytosis.” US & Canadian

Academy of Pathology platform presentation, Hematopathology section, Atlanta, Georgia

2006,“Common diagnostic difficulties in hematopathology.” 9th Annual UCSF & Stanford

University Current Issues in Anatomic Pathology Course, Microscope tutorial with Joan

Etzell, MD, San Francisco, CA

2006,“Introduction to Automated Hematology.” Pediatric Hematology and Oncology

Protocol Meeting, Stanford University, Stanford, CA

2006,“Breast cancer: What is it? Who gets it? How do we treat it?” Canyon Ranch

Educational Seminars, Tucson, Arizona

2006,“Personalized medicine: myth or reality?” Canyon Ranch Educational Seminars,

Tucson, Arizona

2008,“Clinical Microscopy of CSF and Body Fluids: Overview & Focus on Quality

Assurance.” Department of Pathology, The University of New Mexico Health Sciences

Center, School of Medicine, Albuquerque, New Mexico

2008,“Bone marrow histology assessment in mastocytosis patients treated with PKC412

(Midostaurin).” The European Competence Network on Mastocytosis (ECNM),

Budapest, Hungary

2009, “Updates on the Diagnosis and Classification of Myeloproliferative Neoplasms.”

University Medical Center, Utrecht, The Netherlands

2009, “Myelomastocytic leukemia versus mast cell leukemia versus SM-AML: a diagnostic

challenge.” The European Competence Network on Mastocytosis (ECNM), Gdansk,

Poland

2010, “Myelomastocytic leukemia versus mast cell leukemia versus SM-MDS.” Faculty and

Co-chair, Session III: Molecular Pathology in MDS. Standards and Standardization in

Hematopathology in MDS: EU-US initiative to standardize parameters of disease and

diagnostics for practice and clinical trials in patients with MDS, Vienna, Austria

2010, “JAK Who? Update on the 2008 WHO Classification and Clinical Management of

Myeloproliferative Neoplasms.” College of American Pathologists Annual Meeting,

Educational course with Jason Gotlib, MD, MS, Chicago, Illinois

2010, “Myelofibrosis, histologic features.”Arresto BioSciences, Redwood City, CA

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2010, “Myeloid proliferations with eosinophilia and FGFR1 abnormalities.” The European

Competence Network on Mastocytosis (ECNM), Nobel Forum, Stockholm, Sweden,

2011, “Acute myeloid leukemia and occult mastocytosis.” European Bone Marrow Working

Group X International Course on Bone Marrow Pathology, The Old Royal Naval

College, University of Greenwich, London, United Kingdom

2011, “Overview on the diagnosis and classification of myeloproliferative neoplasms.”

Faculty and Co-chair, Session 10: Updates on diagnostic testing for myeloproliferative

neoplasms, International Society of Laboratory Hematology Annual Meeting, New

Orleans, Louisiana,

2012, “Myeloproliferative neoplasms-a case-based presentation.” Faculty and Co-chair,

Session 9: Laboratory testing for hematological malignancies, International Society of

Laboratory Hematology Annual Meeting, Nice, France

2012, “Mast cell disease.” Department of Pathology, Boston Children’s Hospital, Boston,

Massachusetts

2012, “Updates on mastocytosis.” Department of Pathology, The University of New Mexico

Health Sciences Center, School of Medicine, Albuquerque, New Mexico

2012, “Of mast cells and mastocytosis.” ARUP Laboratories, Department of Pathology,

University of Utah School of Medicine, Salt Lake City, Utah

2012, “Myeloid Neoplasms: Morphology to Molecular Genetics.” College of American

Pathologists Annual Meeting, Educational course with Daniel Arber, MD, San Diego,

CA

2012, “Midostaurin in Advanced Mastocytosis.” Symposium on Mastocytosis. Brigham and

Women’s Hospital Mastocytosis Center, Harvard Medical School, Boston, Massachusetts

2012, “Prevalence of Systemic Mastocytosis in Select Myeloid Malignancies- a Single

Institution’s Experience.” Consensus Panel Meeting on Diagnostic Criteria and

Classification of Mastocytosis. Brigham and Women’s Hospital Mastocytosis Center,

Harvard Medical School, Boston, Massachusetts

2012, “Eosinophilia and Mast Cells in Myeloproliferative Neoplasms: ASM-eo versus ASM-

CEL versus MPN-eo.” Consensus Panel Meeting on Diagnostic Criteria and

Classification of Mastocytosis. Brigham and Women’s Hospital Mastocytosis Center,

Harvard Medical School, Boston, Massachusetts

2012, “Diagnosis and monitoring of myeloproliferative neoplasms.” Best of ISLH

(International Society of Laboratory Hematology), HEMO 2012, Brazilian Hematology,

Hemotherapy and Cell Therapy Meeting, Rio de Janeiro, RJ, Brazil

2012, “Mastocytosis.” Grand Rounds, Georgia Health Sciences University Department of

Pathology. Augusta, Georgia

2012, “Malignant or Benign Leukocytosis.” Speaker and Session Chair, Education Program

session: Pearls and Pitfalls in the Hematology Lab: Updates on Cellular Diagnostics, 54th

American Society of Hematology Annual Meeting, Atlanta, Georgia

2013, “Mast cell leukemia.” CPKC412D2201 Steering Committee, Novartis. Venice, Italy,

April 5, 2013

2013, “Challenging Hematopathology Cases.” International Society of Laboratory

Hematology Annual Meeting, Toronto, Canada

2013, “Myeloproliferative Neoplasms (MPN) and MPN Variants - Practical Approach to

Diagnosis and Monitoring.” Educational course with LoAnn Peterson, ASCP Annual

Meeting, September 21, 2013, Chicago, IL

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2013, “Practical Approach to Peripheral Blood Smear Evaluation.” Educational course with

Joan Etzell, Anne Deucher, College of American Pathologists Annual Meeting, Orlando,

FL

2014, “Bench to Bedside: Advances in Mastocytosis" University of New Mexico MD-PhD

program, Albuquerque, NM

2014, “Leukocytosis--when to get worked up?” International Society of Laboratory

Hematology Annual Meeting, World Forum, The Hague, Netherlands

2014, “An Algorithmic Approach to Laboratory Hematology.” Educational course with Joan

Etzell, Sherrie Perkins, American Association of Clinical Chemistry Annual Meeting,

Chicago, IL

2014, “New immunophenotypic assays in mastocytosis.” The European Competence

Network on Mastocytosis (ECNM) Annual Meeting, Odense, Denmark

2014, “Practical Approach to Peripheral Blood Smear Evaluation.” Educational course with

Joan Etzell, Anne Deucher, College of American Pathologists Annual Meeting, Chicago,

IL

2014, “Bone Marrow and Tissue pathology in Patients with Mast Cell Disease.” The

Mastocytosis Society 20th Annual Conference, Rochester, Minnesota

2014, “Pathology: What Confirms a Mast Cell Disorder in Tissue Samples” The

Mastocytosis Society 20th Annual Conference, Rochester, Minnesota

2014, “Evaluation of Leukocytosis.” Educational webinar. Sysmex

2014, “From WHO to New: Updated Approaches to Neoplastic Hematopathology for 2014.”

Educational course with David Czuchlewski. American Society for Clinical Pathology

Annual Meeting, Tampa, FL

2014, “Myeloproliferative Neoplasms (MPN) and MPN Variants - Practical Approach to

Diagnosis and Monitoring.” Educational course with LoAnn Peterson, American Society

for Clinical Pathology Annual Meeting, Tampa, FL

2014, “Update on diffuse large B cell lymphoma”, The Cancer Center at Presbyterian,

Kaseman Hospital, Albuquerque, NM

2015, “An algorithmic approach to leukocytosis,” University of New Mexico Pathology

Seminar Series, Albuquerque, NM

2015 “Leukocytosis, erythrocytosis, thrombocytosis”, Educational Workshop: Updates and

Guidelines in Laboratory Hematology: What’s Current and Practical? International

Society of Laboratory Hematology Annual Meeting, Chicago, IL

2015 “The Diagnosis, Classification and Clinical Care of MDS.” Educational course on

behalf of ASCP, ASH, and The France Foundation, San Francisco, CA

2015 “An Algorithmic Approach to Laboratory Hematology.” Educational course with Joan

Etzell, Sherrie Perkins, American Association of Clinical Chemistry Annual Meeting,

Atlanta, GA

2015 “Novel immunophenotypic markers in mastocytosis” Mast Cells and Mastocytosis - In

Memoriam Paul Ehrlich (1854-1915) Vienna, Austria

2015 “The Diagnosis, Classification and Clinical Care of MDS.” Educational course on

behalf of ASCP, ASH, and The France Foundation, Chicago, IL

2015 “Updates in Systemic Mastocytosis: New Targeted Therapies.” University of New

Mexico Cancer Center, Hematologic Malignancies Joint Adult & Pediatric Quarterly

Meeting, Albuquerque, NM

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2015 “Practical Approach to Peripheral Blood Smear Evaluation.” Educational course with

Joan Etzell, Anne Deucher, College of American Pathologists Annual Meeting,

Nashville, TN

2015 “Morphologic mimics of MDS.” Educational course on behalf of ASCP, ASH, and The

France Foundation. American Society for Clinical Pathology Annual Meeting, Long

Beach, CA

2015 “Practical diagnosis of myeloproliferative neoplasms in the current era: why pathology

matters." Educational course with Robert Hasserjian, Olga Pozdnyakova, American

Society for Clinical Pathology Annual Meeting, Long Beach, CA

2015 “Leukocytosis, erythrocytosis, thrombocytosis,” webinar for International Society of

Laboratory Hematology

(2016) “Bone Marrow Manifestations of Systemic Disease.” Educational course with Dita

Gratzinger, David Czuchlewski, United States and Canadian Academy of Pathology

Annual Meeting, Seattle, WA

(2016) “The Diagnosis, Classification and Clinical Care of MDS.” at the 6th Emirates

Hematology Conference with ASCP, Dubai, United Arab Emirates

(2016) “From Bench to Bedside: Advances in Mastocytosis.” International Society of

Laboratory Hematology Annual Meeting, Milano, Italy

(2016) Peripheral Blood Refresher: a Case-Based Approach. Educational course with Devon-

Chabot Richards, College of American Pathologists Annual Meeting, Las Vegas, NV

(2016) “Practical diagnosis of myeloproliferative neoplasms in the current era: why

pathology matters.” Educational course with Robert Hasserjian, Olga Pozdnyakova,

American Society for Clinical Pathology Annual Meeting, Las Vegas, NV

Community Service:

1993 Speaker, U.C. Berkeley Biomedical ethics class, ~400 students

1993,1995,1996,1997 Women in medicine panel, U.C. Berkeley Preprofessional Advising

1994 Speaker, Upward Bound, Monterey, California

1996 - 1998 Advisory Board Member, Kappa Alpha Theta, Omega chapter

2006 Faculty participant, Packard 101: A day at Lucile Packard Children’s

Hospital for community members

2005 - 2011 New Century Chamber Orchestra, Board of Directors

Tracy George 10

Short narrative of research, teaching and service interests My scholarly work has focused on translational projects in hematopathology derived from my clinical work as a diagnostic

hematopathologist. I have focused on research in myeloproliferative neoplasms, specifically mast cell disease, which I began

over 10 years ago. My investigative activities include ongoing participation in several large multi-institutional clinical trials.

While I am not typically the primary or senior author on manuscripts resulting from these trials, my contributions are

typically substantial and include participation in trial design, data gathering and analysis, authorship of sections of the

manuscript, participation in final review of the manuscript, and presentation of the work at national meetings.

After publishing a review on the pathology of the myeloproliferative diseases in 2003, I began to focus on this area,

subsequently publishing book chapters and articles. Clinically, I began to work closely with Dr. Gotlib, a Stanford

hematologist who treats patients with myeloproliferative neoplasms. I soon found myself diagnosing Dr. Gotlib’s more

difficult patients. One such patient had mast cell leukemia, a very rare myeloproliferative neoplasm with no known effective

treatment. Dr. Gotlib used a novel protein tyrosine kinase inhibitor, midostaurin, to treat this patient after recognizing that

this drug showed inhibition of a cell line with the D816V KIT mutation, a mutation characteristic of patients with mast cell

disease. Dr. Gotlib and I documented the first bone marrow response to this drug. This exciting work resulted in an

investigator-initiated trial of the drug in patients with aggressive mast cell disease, followed shortly by an international

clinical trial by Novartis. In diagnosing these rare patients with aggressive mast cell disease, I have become a world expert in

the diagnosis of mastocytosis. I have been fortunate to collaborate with Dr. Peter Horny (University of Munich), a well-

recognized world expert in mastocytosis; we published a review together on this subject in 2010 and I have been a coauthor

on publications on this topic in Blood, American Journal of Hematology, Best Practice & Research Clinical Haematology,

and Current Cancer Therapy Reviews. At that time, I also mentored medical student, then resident, Dr. Angela Arredondo

and we published a series of unusual cases of acute leukemia with mast cell features in the American Journal of Hematology.

I presented this work at the invitation of the leading scientific organization in mastocytosis, the European Competence

Network in Mastocytosis (ECNM), in Gdansk, Poland in 2009. In 2010, I presented additional work as part of an

international conference on “Standards and Standardization in Hematopathology in myelodysplastic syndrome (MDS): EU-

US initiative to standardize parameters of disease and diagnostics for practice and clinical trials in patients with MDS,” in

Vienna. Since that time, I presented at ECNM at The Nobel Form, Stockholm, Sweden in 2010 on “Myeloid proliferations

with eosinophilia and FGFR1 abnormalities,” another rare disease that also contains neoplastic mast cells. My trainee, Dr.

Arredondo, gave an oral presentation of our work on “CD30 expression in mastocytosis” at ECNM in 2011 in Istanbul,

Turkey; she also had a poster presentation that year at the annual meeting of the US and Canadian Academy of Pathology, the

leading group of academic pathologists in the world. This work has resulted in a clinical trial of an anti-CD30 therapy in

aggressive mast cell disease. I have published subsequent work in this area with multiple trainees, presented in national and

international meetings, resulting in several publications.

With respect to teaching, I enjoy teaching students and colleagues at all levels, from medical students to residents/fellows to

medical technologists to pathologists. Recently, I taught patients with mast cell disease at The Mastocytosis Society which

was a novel experience. At my previous institution, I codirected the Hematology section of Human Health & Diseases 223

for the School of Medicine for 7 years where we had the most successful medical student course of the second year of

medical school, using didactic lectures coupled with small group learning sessions. I incorporated digital whole slide imaging

into my lectures and received recognition for “Excellence in Teaching” for these activities in 2008, 2010, and 2011. More

recently, I have been involved in UNM’s Genetic and Neoplasia course being a small group tutor for 8 medical students, as

well as lecturing and leading larger group sections. For the pathology residency program, I was the Chair of the Clinical

Competency Committee, implementing the new ACGME milestones this past year. Our program evaluation committee

successfully implemented a resident-faculty retreat, an idea I championed. I am also the Hematopathology Fellowship

Director of UNM with 4 fellows, considered one of the top programs in the nation. Our program also successfully

implemented ACGME milestones, one year early, and I have focused our fellowship on research and quality improvement

projects for all fellows with our faculty. With respect to pathologists, I teach courses nationally at our pathology

organizations, including ASCP, CAP, and AACC; I received the CAP Lifetime Achievement Award in 2014. In 2015, I

chaired a national steering committee which implemented a new teaching curriculum and methods in myelodysplastic

syndrome; this was funded by an educational grant put forth by 3 non-profit groups (ASCP, ASH, the France Foundation).

Finally, I am the Division Chief of Hematopathology, where I lead a group of 7 faculty specializing in the diagnosis of

diseases of bone marrow and lymph nodes. In addition to diagnosing the patients of UNM, we run a large consultation

service to help other pathologists diagnose difficult cases. I am now the director for the Genetics and Cytometry Laboratories

at TriCore Reference Labs, all focused on testing necessary for hematopathology. I strive to maintain the high standards and

excellent quality our division provides, while also implementing test utilization to reduce unnecessary testing and initiate

appropriate lab testing for all of our patients.

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Scholarly achievements: (trainees underlined)

Books (3 total)

1. Dennis P O’Malley, MD, Tracy I George, MD, Attilio Orazi, MD, FRCPath, Susan L

Abbondanzo, MD. Atlas of Nontumor Pathology, First Series, Fascicle 7: Benign and

Reactive Conditions of Lymph Node and Spleen. American Registry of Pathology &

Armed Forces Institute of Pathology, Washington DC, 572 pages, 2009.

2. Irma Pereira, MT (ASCP), SH, Tracy I George, MD, Daniel A Arber, MD. Atlas of

Peripheral Blood. The Primary Diagnostic Tool. Wolters Kluwer, Lippincott Williams

and Wilkins, Inc., Philadelphia, PA, 194 pages, 2012.

3. Joan E Etzell, MD, FCAP, Martha R Clarke, MD, FCAP, George Girgis, MT (ASCP),

Alice L Werner, MD, FCAP, Anna K Wong, MD, FCAP, Tracy I George, MD, FCAP.

Body Fluid Bench Top Reference Guide. College of American Pathologists; Northfield,

IL, 42 pages, 2013.

Peer-reviewed Original Articles (65 total)

1. MG Pallavicini, T George, PS DeTeresa, R Amendola, JW Gray. Intracellular

dynamics of c-myc mRNA traffic in single cells in situ. J Cellular Physiology

1994;158:223-230.

2. G Sauter, G Deng, H Moch, R Kerschmann, K Matsumura, S Devries, T George, J

Fuentes, P Carroll, MJ Mihatsch, F Gudat, F Waldman. Physical deletion of the p53

gene in bladder cancer: Detection by fluorescence in situ hybridization. American J

Pathology 1994;144:756-766.

3. B Mehrotra, T George, K Kavanau, H Aviet-Loiseau, D Moore II, C Willman, M

Slovak, S Atwater, D Head, M Pallavicini. Cytogenetically aberrant cells in the stem

cell compartment (CD34+lin-) in acute myeloid leukemia and myelodysplasia. Blood

1995;86:1139-1147.

4. JH Khan, SB Rahman, C Clary-Macy, B Kerlin, TI George, G Rosa, T Hall, D

Jablons. Giant solitary fibrous tumor of the pleura. AnnThorac Surg 1998;65:1461-

1464.

5. JH Khan, DB McElhinney, SB Rahman, TI George, OH Clark, SM Merrick.

Pulmonary metastases of endocrine origin, the role of surgery. Chest 1998;114:526-

534.

6. TI George, G Manley, JE Koehler, VS Hung, M McDermott, A Bollen. Detection of

Bartonella henselae by polymerase chain reaction in brain tissue of an

immunocompromised patient with multiple enhancing lesions. Case report and review

of the literature. J Neurosurg1998;89:640-644.

7. L Esserman, N Hylton, T George, N Weidner. Contrast-enhanced magnetic resonance

imaging to assess tumor histopathology and angiogenesis in breast carcinoma. The

Breast Journal 1999;5;13-21.

8. DT Stucker, DM Ikeda, A-R Hartman, TI George, KW Nowels, SL Birdwell D

Goffinet, RW Carlson. New bilateral microcalcifications at mammography in a post-

lactational woman. Radiology 2000;217:247-250.

9. QT Le, SM Eulau, TI George, R Hildebrandt, RA Warnke, SS Donaldson, RT Hoppe.

Primary Radiotherapy for Localized Orbital MALT Lymphoma. Int J Radiat Oncol

Biol Phys 2002;52:657-663.

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10. TI George, CD Jones, JL Zehnder, RA Warnke, RF Dorfman. Lack of human

herpesvirsus 8 & Epstein-Barr virus in Kikuchi’s histiocytic necrotizing

lymphadenitis. Human Pathology 2003; 34:130-135.

11. D MacDermed, L Thurber, TI George, RT Hoppe, Q-T Le. Extranodal nonorbital

indolent lymphomas of the head and neck: relationship between tumor control and

radiotherapy. Int J Radiation Oncology Biol Phys 2004;59:788-795.

12. TI George, M Jeng, W Berquist, A Cherry, M Link, DA Arber. Epstein-Barr virus-

associated peripheral T-cell lymphoma arising after liver transplantation. Pediatric

Blood and Cancer 2005;44:270-276.

13. TI George, JE Wrede, CD Bangs, AM Cherry, RA Warnke, DA Arber. Low grade B-cell

lymphomas with plasmacytic differentiation lack PAX5 gene rearrangements. J Molec

Diagnostics 2005;7(3):346-351.

14. J Gotlib, C Berube, JD Growney, C-C Chen, TI George, C Williams, T Kajiguchi, J

Ruan, SL Lilleberg, JA Durocher, JH Lichy, Y Wang, PS Cohen, D Arber, C Heinrich, L

Neckers, S J Galli, D G Gilliland, and SE Coutre. Activity of the tyrosine kinase inhibitor

PKC412 in a patient with mast cell leukemia with the D816V KIT mutation. Blood

2005;106(8):2865-2870.

15. JE Wrede, U Sundram, S Kohler, AM Cherry, DA Arber, TI George. Fluorescence in

situ hybridization investigation of cutaneous lesions in acute promyelocytic leukemia.

Modern Pathology 2005;18(12):1569-1576 .

16. S Dutt, J Ermann, D Tseng, YP Liu, TI George, CG Fathman, S Strober. L-selectin and

b7 integrin on donor CD4 T cells are required for the early migration to host mesenteric

lymph nodes and acute colitis of graft versus host disease. Blood 2005;106(12):4009-

4015.

17. DA Arber, TI George. Bone marrow biopsy involvement by non-Hodgkin lymphoma:

frequency of lymphoma types, patterns, blood involvement and discordance with other

sites in 450 specimens. American Journal of Surgical Pathology 2005;29(12):1549-1557.

18. C Krishnan, TI George, DA Arber. Bone marrow metastases: a survey of

nonhematologic metastases with immunohistochemical study of metastatic carcinomas.

Applied Immunohistochemistry & Molecular Morphology 2007;15(1):1-7.

19. AB Pillai, TI George, S Dutt, P Teo, S Strober. Host NK T cells can prevent graft-

versus-host disease and permit graft antitumor activity after bone marrow transplantation.

J Immunol 2007; 178(10):6242-6251.

20. AB Pillai, P Teo, TI George, A Mukhopadhyay, S Dejbahksh-Jones, S Strober.

Alloantigen recognition is critical for CD8 T cell-mediated graft anti-tumor activity

against murine BCL1 lymphoma after myeloablative bone marrow transplantation. Bone

Marrow Transplant 2007; 40(5):487-497.

21. S Dutt, J Ermann, D Tseng, YP Liu, TI George, CG Fathman, S Strober. Naive and

memory T cells induce different types of graft versus host disease. J Immunol 2007;

179(10):6547-6554.

22. MM O’Brien, Y Lee-Kim, TI George, K McClain, CJ Twist, M Jeng. Precursor B-cell

acute lymphoblastic leukemia presenting with hemophagocytic lymphohistiocytosis.

Pediatric Blood and Cancer 2008; 50(2):381-383.

23. J Cupp, JE Wrede, AM Cherry, DA Arber, TI George. Chromosomal aberrations in a

case of synchronous extranodal marginal zone B-cell lymphoma of mucosa-associated

Tracy George 13

lymphoid tissue type and bronchogenic adenocarcinoma. Applied Immunohistochemistry

& Molecular Morphology 2008;16 (3):296-300.

24. I Gutgemann, K Stevens, D Loftus, IG Schmidt-Wolf, TI George. VEGF and

osteosclerosis in POEMS syndrome. Annals of Hematology 2008; 87(3):243-245.

25. CC Dvorak, A Sandford, A Fong, MJ Cowan, TI George, DB Lewis. Maternal T-cell

engraftment associated with severe hemophagocytosis of the bone marrow in untreated

X-linked severe combined immunodeficiency. J Pediatric Hematology and Oncology

2008;30(5):396-400.

26. SM Chan, T George, AM Cherry, BC Medeiros. Complete remission of primary plasma

cell leukemia with bortezomib, doxorubicin, and dexamethasone. Cases Journal 2009;

2:121.

27. AB Pillai, TI George, S Dutt, S Strober. Host natural killer T cells induce an IL-4

dependent expansion of donor CD4+CD25+Foxp3+ Tregs that protects against graft-

versus-host disease. Blood 2009 113(18):4458-67.

28. A Pellagatti, T Marafioti, JC Paterson, L Malcovati, MG Della Porta, M Jädersten, B

Pushkaran, TI George, DA Arber, S Killick, A Giagounidis, E Hellström-Lindberg, M

Cazzola, JS Wainscoat, J Boultwood. Marked downregulation of the granulopoiesis

regulator LEF1 is associated with disease progression in the myelodysplastic syndromes.

Br J Haematol 2009 Jun;146(1):86-90. Epub 2009 May 5.

29. D Cronin, TI George, U Sundram. An updated approach to the diagnosis of myeloid

leukemia cutis. American Journal of Clinical Pathology 2009; 132:101-110.

30. DA Pollyea, TI George, C Corless, J Gotlib. When Yellow Jackets Attack: Recurrent

and severe anaphylactic reactions to insect bites and stings. American Journal of

Hematology 2009 Dec; 84(12):843-6.

31. G Mattsson, SH Turner, J Cordell, DJ Ferguson, A Schuh, LF Grimwade, AJ Bench, OK

Weinberg, T Marafioti, TI George, DA Arber, WN Erber, DY Mason. Can cytoplasmic

nucleophosmin be detected by immunocytochemical staining of cell smears in acute

myeloid leukemia? Haematologica 2010;95(4):670-3.

32. AR Arredondo, J Gotlib, L Shier, B Medeiros, K Wong, A Cherry, C Corless, DA Arber,

P Valent, TI George. Myelomastocytic leukemia versus mast cell leukemia versus

systemic mastocytosis associated with acute myeloid leukemia: a diagnostic challenge.

American Journal of Hematology 2010;85(8):600-6.

33. P Valent, M Arock, C Akin, WR Sperr, A Reiter, K Sotlar, K Hartmann, TI George, K

Brockow, HC Kluin-Nelemans, J Gotlib, DD Metcalfe, HP Horny. The classification of

systemic mastocytosis should include mast cell leukemia (MCL) and systemic

mastocytosis with a clonal hematologic non-mast cell lineage disease (SM-AHNMD).

Blood 2010; 116:850-1.

34. P Valent, A Orazi, G Büsche, A Schmitt-Gräff, TI George, K Sotlar, B Streubel, C

Beham-Schmid, S Cerny-Reiterer, O Krieger, An van de Loosdrecht, W Kern, I Ogata, F

Wimazal, J Csomor, J Várkonyi, WR Sperr, M Werner, H Kreipe, H-P Horny. Standards

and impact of hematopathology in myelodysplastic syndromes (MDS). Oncotarget

2010;1(7):483-96.

35. P Valent, S Cerny-Reiterer, H Herrmann, I Mirkina, TI George, K Sotlar, WR Sperr, H-

P Horny. Phenotypic heterogeneity, novel diagnostic markers, and target expression

profiles in normal and neoplastic human mast cells. Best Pract Res Clin Hem 2010;

23:369-78.

Tracy George 14

36. B Tan, A Nava, TI George. Evaluation of the Beckman Coulter UniCel DxH 800 and

Abbott Diagnostics Cell-Dyn Sapphire hematology analyzers on pediatric and neonatal

specimens in a tertiary care hospital. Am J Clin Pathol 2011;135:929-938.

37. B Tan, A Nava, TI George. Evaluation of the Beckman Coulter UniCel DxH 800,

Beckman Coulter LH 780, and Abbott Diagnostics Cell-Dyn Sapphire hematology

analyzers on adult specimens in a tertiary care hospital. Am J Clin Pathol 2011;135:939-

951.

38. G Wernig, MG Kharas, A Mullally, DS Leeman, R Okabe, T George, DO Clary, DG

Gilliland. EXEL−8232, a small-molecule JAK2 inhibitor, effectively treats

thrombocytosis and extramedullary hematopoiesis in a murine model of

myeloproliferative neoplasm induced by MPLW515L Leukemia 2012;26(4):720-7.

39. C Ustun, NM Savage, J Gotlib, K Bhalla, E Manaloor, TI George. Systemic

Mastocytosis with Associated Clonal Hematological Non-Mast-Cell Lineage Disease: A

Case Review. Am J Hematol 2012;87(2):191-3.

40. D Cronin, TI George, KK Reichard, UN Sundram. Immunophenotypic Analysis of

Myeloperoxidase-Negative Leukemia Cutis and Blastic Plasmacytoid Dendritic Cell

Neoplasm. Am J Clin Pathol 2012;137:367-376.

41. M DiMaio, I Pereira, TI George, N Banaei. Performance of BinaxNOW for diagnosis of

malaria in the U.S. hospital. J Clin Microbiol; 2012;50(9):2877-80.

42. R Sachdev, TI George, EJ Schwartz, UN Sundram. Discordant Immunophenotypic

Profiles of Adhesion Molecules and Cytokines in Acute Myeloid Leukemia involving

Bone Marrow and Skin. Am J Clin Pathol 2012;138:290-299.

43. TI George. Malignant or Benign Leukocytosis. Hematology Am Soc Hematol Educ

Program. 2012;2012: 475-84.

44. M Lefterova, C Rivetta, TI George, B Pinsky. Severe Hepatitis Associated with an

Echovirus 18 infection in an Immune Compromised Adult. J Clin Microbiol

2013;51(2):684-7.

45. NM Savage, RC Johnson, J Gotlib, TI George. Myeloid and Lymphoid Neoplasms with

FGFR1 Abnormalities: diagnostic and therapeutic challenges. Am J Hematol 2013;

88(5):427-430.

46. R Agrawal, C Berube, G Steinberg, TI George. Moyamoya Syndrome with Sickle Cell

Trait. International Journal of Laboratory Hematology 2013;35(5):e8-9.

47. J Gotlib, A Pardanani, C Akin, A Reiter, T George, O Hermine, H Kluin-Nelemans, K

Hartmann, WR Sperr, K Brockow, LB Schwartz, A Orfao, DJ DeAngelo, M Arock, K

Sotlar, HP Horny, DD Metcalfe, L Escribano, S Verstovsek, A Tefferi, and P Valent. International Working Group-Myeloproliferative Neoplasms Research and Treatment &

European Competence Network on Mastocytosis Consensus Response Criteria in

Advanced Systemic Mastocytosis. Blood 2013;121(13):2393-401.

48. S Dinner, W Witteles, R Witteles, A Lam, S Arai, R Lafayette, TI George, SL Schrier,

M Liedtke. The prognostic value of diagnosing concurrent multiple myeloma in

immunoglobulin light chain amyloidosis. Br J Haematol 2013;161(3):367-72.

49. JD Merker, KM Roskin, D Ng, C Pan, DG Fisk, JJ King, R Hoh, M Stadler, LM

Okumoto, P Abidi, R Hewitt, CD Jones, L Gojenola, MJ Clark, B Zhang, AM Cherry, TI

George, M Snyder, SD Boyd, JL Zehnder, AZ Fire, J Gotlib. Comprehensive whole-

genome sequencing of an early-stage primary myelofibrosis patient defines low

Tracy George 15

mutational burden and non-recurrent candidate genes. Haematologica 2013;98(11):1689-

96.

50. J Gotlib, JE Maxson, TI George, JW Tyner. The new genetics of chronic neutrophilic

leukemia and atypical CML: implications for diagnosis and treatment. Blood

2013;122(10):1707-11.

51. RC Johnson, L Ma, AM Cherry, DA Arber, TI George. B-cell transcription factor

expression and immunoglobulin gene rearrangement frequency in acute myeloid

leukemia with t(8;21)(q22;q22). Am J Clin Pathol 2013;140(3):355-62.

52. RC Johnson, NM Savage, T Chiang, A Cherry, JR Gotlib, DA Arber, TI George. Hidden

Mastocytosis in AML with t(8;21). Am J Clin Pathol 2013;140(4):525-35.

53. JM Morgado, O Perbellini, RC Johnson, C Teodósio, A Matito, I Álvarez-Twose, P

Bonadonna, A Zamò, M Jara-Acevedo, A Mayado, A Garcia-Montero, M Mollejo, TI

George, R Zanotti, A Orfao, L Escribano and L Sánchez-Muñoz. CD30 expression by

bone marrow mast cells from different diagnostic variants of systemic mastocytosis.

Histopathology 2013;63(6):780-7.

54. N Golardi, JE Sramek, JB Myers, H Saffer, TI George, D Czuchlewski. Two cases of

concomitant acquired aplastic anemia and systemic mastocytosis. Human Pathology

2014;45(2):417-20. Epub 2013 Oct 31.

55. G Bourner, B De la Salle, T George, Y Tabe, H Baum, N Culp, TB Keng on behalf of

the International Committee for Standardization in Hematology (ICSH). ICSH

Guidelines for the Verification and Performance of Automated Cell Counters for Body

Fluid. International Journal of Laboratory Hematology 36(6):598-612, Epub 2014 Mar

14.

56. P Valent, K Sotlar, WR. Sperr, L Escribano, S Yavuz, A Reiter, TI George, HC Kluin-

Nelemans, O Hermine, J H Butterfield, H Hägglund, C Ustun, JL Hornick, M Triggiani,

D Radia, C Akin, K Hartmann, J Gotlib, LB Schwartz, S Verstovsek, A Orfao, DD

Metcalfe, M Arock, H-P Horny. Refined diagnostic criteria and classification of mast cell

leukemia (MCL) and myelomastocytic leukemia (MML): a consensus proposal. Ann

Oncol 2014;25(9):1691-700.

57. D Chabot-Richards, TI George. Leukocytosis. International Journal of Laboratory

Hematology 2014;36(3):279-88. Epub 2014 Apr 18.

58. LS Ludwig, HT Gazda, JC Eng, SW Eichhorn, P Thiru, R Ghazvinia, TI George, JR

Gotlib, AH Beggs, CA Sieff, HF Lodish, ES Lander, and VG Sankaran. Altered

translation of GATA1 in Diamond-Blackfan anemia. Nature Medicine 2014;20(7):748-

53. Epub 2014 Jun 22..

59. RP Hasserjian, F Campigotto, V Klepeis, B Fu, SA Wang, C Bueso-Ramos, MJ Cascio,

HJ Rogers, ED Hsi, C Soderquist, A Bagg, J Yan, RC Ochs, A Orazi, F Moore, A

Mahmoud, TI George, K Foucar, J Oderm , C Booth, W Morice, DJ DeAngelo, D

Steensma, RM Stone, D Neuberg, DA Arber. De novo acute myeloid leukemia with 20-

29% blasts is less aggressive than acute myeloid leukemia with ≥30% blasts in older

adults: a Bone Marrow Pathology Group study. Am J Hematol 2014; 89(11):E193-9.

Epub 2014 July 31.

60. AZ Mahmoud, TI George, DR Czuchlewski, QY Zhang, CS Wilson, CE Sever, AG

Bakhirev, D Zhang, NL Steidler, KK Reichard, H Kang, K Foucar, MA Vasef. Scoring of

MYC protein expression in diffuse large B-Cell lymphomas: concordance rate among

hematopathologists. Modern Pathology 2014 Nov 28. [Epub ahead of print].

Tracy George 16

61. KM Chisholm, JD Merker, JR Gotlib, G Gitana, M Lefterova, JL Zehnder, TI George,

DA Arber, RS Ohgami. Mast cells in systemic mastocytosis have distinctly brighter

CD45 expression by flow cytometry. Am J Clin Pathol 2015;143(4):527-34.

62. AM Deucher, Z Qi, TI George, JE Etzell. BCL6 expression correlates with the t (1;19)

translocation in B-cell lymphoblastic leukemia. Am J Clin Pathol 2015;143(4):547-57.

63. J Hughes, J McNaughton, J Andrews, T George, C Bergero, K Pyke-Grimm, SA Galel,

C Gonzalez, LT Goodnough, MJ Fontaine. Infusion pump-mediated mechanical

hemolysis in pediatric patients. Ann Clin Lab Sci 2015;45(2):140-7.

64. CPM Hayward, KA Moffat, TI George, M Proytcheva. Assembly and evaluation of an

inventory of guidelines that are available to support clinical hematology laboratory

practice. International Journal of Laboratory Hematology 2015, 37 (Suppl 1):36-45.

65. K Hartmann, L Escribano, C Grattan, K Brockow, MC Carter, I Alvarez-Twose, A

Matito, S Boresby-Olsen, F Siebenhaar, M Lange, M Niedoszytko, M Castells, JNG

Oude Elberink, P Bonnadonna, R Zanotti, JL Hornick, A Torrelo, A Rabenhorst, B

Nedoszytko, JH Butterfield, J Gotlib, A Reiter, D Radia, O Hermine, K Sotlar, TI

George, TK Kristensen, HC Kluin-Nelemans, S Yavuz, H Hagglund, WR Sperr, LB

Schwartz, M Triggiani, M Maurer, G Nilsson, H-P Horny, M Arock, A Orfao, DD

Metcalfe, C Akin, P Valent. Cutaneous manifestations in mastocytosis: consensus report

of the European Competence Network on Mastocytosis; the American Academy of

Allergy, Asthma & Immunology; and the European Academy of Allergology and Clinical

Immunology. J Allergy Clin Immunol 2015 Oct 15. [Epub ahead of print]

Review articles and chapters: (12 total, 2 pending)

1. TI George & DA Arber. Pathology of the Myeloproliferative Diseases. In: Hematology

/Oncology Clinics of North America, N Berlin (editor),WB Saunders Company,

Philadelphia, 17:1101-1127, 2003.

2. TI George. Chronic Myeloproliferative Syndromes. In: Wintrobe’s Atlas of Clinical

Hematology, Tkachuk D, Hirschmann JV (editors). Wolters Kluwer, Lippincott Williams

and Wilkins, Inc., Philadelphia, pp 105-136, 2007.

3. TI George. Pathology of the Myeloproliferative Diseases. In: Wintrobe’s Clinical

Hematology, Twelth Edition. Greer JP, Foerster J, Rodgers GM, Paraskevas F, Glader B,

Arber DA, Means RT (editors). Lippincott Williams and Wilkins, Inc., Philadelphia,

2008.

4. TI George, HP Horny. Systemic mastocytosis. In: Current Concepts in Hematopathology:

Applications in Clinical Practice, Surgical Pathology, RP Hasserjian (editor), WB

Saunders Company, Philadelphia, 3(4):1185-1202, 2010. Reprinted in

Hematology/Oncology Clinics of North America Oct;25(5):1067-83, 2011.

5. TI George. Mastocytosis. Current Cancer Therapy Reviews 8(1):35-43, 2012.

6. N Savage, TI George, J Gotlib. Myeloid Neoplasms Associated with Eosinophilia and

Rearrangement of PDGFRA, PDGFRB and FGFR1: A Review. International Journal of

Laboratory Hematology 2013;35(5):491-500.

7. RC Johnson, TI George. The differential diagnosis of eosinophilia in neoplastic

hematopathology. In: Hematopoietic Neoplasms: Controversies in Diagnosis and

Classification, Surgical Pathology, TI George and DA Arber (editors), Elsevier,

Philadelphia, 6(4):767-794, 2013.

Tracy George 17

8. LR Shier and TI George. Pathology of the Myeloproliferative Neoplasms. In: Wintrobe’s

Clinical Hematology, Thirteenth Edition. Greer JP, Rodgers GM, Glader B, Arber DA,

Means RT, List A (editors). Lippincott Williams and Wilkins, Inc., Philadelphia,

pp1688-1704, 2013.

9. D Chabot-Richards and TI George. White Blood Cell Counts: Reference Methodologies.

In: Automated Cell Counters: State of the Art and New Directions. Clinics in Laboratory

Medicine, C Brugnara, A Kratz (editors), Elsevier, Philadelphia, 35(1):11-24, 2015.

10. M Harrison, TI George. Automated Hematology Parameters: New (and not so new)

parameters and their clinical utility are explored. Advance for Administrators of the

Laboratory 24(9):28-31, 2015.

11. TI George, K Sotlar, P Valent, H-P Horny. Mastocytosis. In: Hematopathology, Second

Edition. ES Jaffe, NL Harris, JW Vardiman, E Campo, DA Arber (editors). Elsevier,

Philadelphia, (in press).

12. B Tan and TI George. Myeloproliferative neoplasms. In: Tkachuk D, Hirschmann JV

(editors). Wintrobe’s Atlas of Clinical Hematology, Second Edition. Lippincott Williams

and Wilkins, Inc., Philadelphia (in press).

Other writings and scholarly products: (39 total, 3 pending)

1. TI George. Automated Hematology Instrumentation. In: Rose, BD (editor). Up to Date

Wellesley: Up to Date, Inc; (2003-2015), updated each year.

2. TI George. Large cell lymphoma. CAP Hematology/Clinical Microscopy Resource

Committee Participant Summary Report and Educational Activity with questions for

CE/CME credit. Survey HE-B. Northfield, IL: College of American Pathologists; June

2006.

3. TI George. Hereditary Pelger Huet change. CAP Hematology/Clinical Microscopy

Resource Committee Participant Summary Report. Survey HE-A. Northfield, IL: College

of American Pathologists; January 2008.

4. TI George, H Kohrt . Evaluation of neutrophilia. BMJ Point-of-Care 2009-2015; updated

each year, www.pointofcare.bmj.com.

5. TI George. Systemic lupus erythematosus. CAP Hematology/Clinical Microscopy

Resource Committee Participant Summary Report. Survey HE-B. Northfield, IL: College

of American Pathologists; June 2009.

6. TI George. Q&A on low WBC in oncology patients. CAP TODAY, July 2009. College of

American Pathologists, Northfield, IL.

7. TI George & CS Wilson. Hereditary elliptocytosis. CAP Hematology/Clinical

Microscopy Resource Committee Participant Summary Report with questions for

CE/CME credit. Survey HE-C. Northfield, IL: College of American Pathologists;

October 2009.

8. TI George, KT Bradley, SL Perkins. Primary myelofibrosis. CAP Hematology/Clinical

Microscopy Resource Committee Participant Summary Report and Educational Activity

with questions for CE/CME credit. Survey HE-B. Northfield, IL: College of American

Pathologists; June 2010.

9. TI George. Q&A on laboratory values in polycythemic patients. CAP TODAY, August

2010. College of American Pathologists, Northfield, IL.

Tracy George 18

10. J. Gotlib, TI George. JAK Who? Update on the 2008 WHO Classification and Clinical

Management of Myeloproliferative Neoplasms. CME/Self-assessment module.

Northfield, IL: College of American Pathologists, September 2010.

11. TI George, KT Bradley, SL Perkins. Chronic myelogenous leukemia. CAP

Hematology/Clinical Microscopy Resource Committee Participant Summary Report and

Educational Activity with questions for CE/CME credit. Survey HE-C. Northfield, IL:

College of American Pathologists; October 2010.

12. TI George. Q&A on hematology QC materials. CAP TODAY, May 2011. College of

American Pathologists, Northfield, IL.

13. KT Bradley, TI George. Acute myeloid leukemia arising from polycythemia vera. CAP

Hematology/Clinical Microscopy Resource Committee Participant Summary Report and

Educational Activity with questions for CE/CME credit. Survey HE-B. Northfield, IL:

College of American Pathologists; June 2011.

14. TI George, C Dunphy, L Contis. CAP Competency Model for Pathologists, Dictionary

Pages for Hematology/Hematopathology. College of American Pathologists, Northfield,

IL; published in the CAP Learning Portal October 2011.

15. A Wong, TI George. Dengue fever. CAP Hematology/Clinical Microscopy Resource

Committee Participant Summary Report with Self-reported CE credit. Survey HE-C.

Northfield, IL: College of American Pathologists; October 2012.

16. TI George. Myelodysplastic syndrome. CAP Hematology/Clinical Microscopy Resource

Committee Participant Summary Report with Self-reported CE credit. Survey EHE1-B.

Northfield, IL: College of American Pathologists; November 2012.

17. TI George. Q&A on normal RBC count and a low hemoglobin and hematocrit. CAP

TODAY, December 2012. College of American Pathologists, Northfield, IL.

18. TI George. Basophilia (digital text chapter). In: Laposata, Melanson, Alter (editors).

Clinical Decision Support on Lab Medicine, Decision Support in Medicine, LLC; 2013.

19. TI George. Q&A on smudge cells. CAP TODAY, May 2013. College of American

Pathologists, Northfield, IL.

20. M Lefterova, TI George. Plasmodium vivax. CAP Hematology/Clinical Microscopy

Resource Committee Participant Summary Report and Educational Activity with

questions for CE/CME credit. Survey HE-B. Northfield, IL: College of American

Pathologists; June 2013.

21. RC Johnson, TI George. Chronic myelogenous leukemia in the CSF. CAP Hematology/

Clinical Microscopy Resource Committee Participant Summary Report with Self-

reported CE credit. Survey CMP-A. Northfield, IL: College of American Pathologists;

June 2013.

22. J Oliveira, TI George. Cold agglutinin disease. CAP Hematology/Clinical Microscopy

Resource Committee Participant Summary Report and Educational Activity with

questions for CE/CME credit. Survey VPBS-B. Northfield, IL: College of American

Pathologists; October 2013.

23. TI George. Q&A on ghost cells and automated body fluid cell counts. CAP TODAY,

Feb 2014. College of American Pathologists, Northfield, IL.

24. TI George, J Gotlib, J Etzell. Eosinophilia. CME/Self-assessment module. Northfield,

IL: College of American Pathologists, 2014.

25. D Wong, TI George. Thrombopoietin receptor agonist-associated reticulin fibrosis and

megakaryocyte atypia. BloodMed June 1, 2014; image 387.

Tracy George 19

26. JL Oliveira, TI George. 2014 CPIP-H Case 08: Hematology – Cold Agglutinins (SAM

eligible). © 2014 College of American Pathologists - Online CME Self Assessment

Module released August, 2014.

27. A Deucher, TI George, J Etzell. Practical Approach to Peripheral Blood Smear

Evaluation. CME/Self-assessment module. College of American Pathologists, September

2014.

28. TI George. Q&A on variation in hemoglobin. CAP TODAY, Sept 2014. College of

American Pathologists, Northfield, IL.

29. B Menkhaus, TI George. Eosinophilia. CAP Hematology/Clinical Microscopy Resource

Committee Participant Summary Report and Educational Activity with questions for

CE/CME credit. Survey VPBS-B. Northfield, IL: College of American Pathologists;

December 2014.

30. T George; B Menkhaus 2015 CPIP-C Case 3: Eosinophilia (SAM eligible)

© 2015 College of American Pathologists - Online CME Self Assessment Module

released March 23, 2015.

31. TI George. Variation in cancer risk: nature, nurture, and random chance. The

Hematologist, Mar/Apr 2015; 12(2):9.

32. TI George. The Tumor Microenvironment as a Key to MPN Pathogenesis. The

Hematologist, May/June 2015;12(3):9.

33. TI George and E Lockhart. Fresher blood is not necessarily better blood. The

Hematologist, July/Aug 2015; 12(4):11.

34. TI George. Computed Tomography Provides No Benefit over Routine Screening for

Occult Cancer. The Hematologist, Sept/Oct 2015; 12(5):8.

35. TI George. Ask the Hematopathologist: Diagnostic Approach to Lymphocytosis. The

Hematologist, Nov/Dec 2015; 12(6):4-5.

36. MK Harrison and TI George. Acquired Aplastic Anemia: Somatic Mutations and

Eltrombopag Take the Spotlight. The Hematologist, Jan/Feb 2016; 13(1):10.

37. D Lynch and TI George. Mutated Calreticulin Stimulates the Thrombopoietin Receptor

to Drive the Development of MPN. The Hematologist, Mar/Apr 2016; in press.

38. D Bustamante and TI George. Bone Marrow Biopsy Evaluation for Mast Cell Disorders.

The Mastocytosis Society web site; in press.

39. D Chabot-Richards and TI George. Acute myeloid leukemia MRD comes of age. The

Hematologist, May/June 2016; in press.

Selected Abstracts (44 of 67 total):

1. TI George, RA Warnke, DA Arber. Differentiating acute promyelocytic leukemia from

growth factor-associated reactive proliferations using paraffin section

immunophenotyping. Modern Pathology 17:249A, 2004, USCAP.

2. TI George, FL Baehner, YN Natkunam, S Geaghan, B Brown, DA Arber. Bone marrow

biopsy for focal disease detection: evaluation of optimal biopsy length and comparison of

bilateral to equivalent-length unilateral biopsies. Modern Pathology 17:248A, 2004,

USCAP.

3. TI George, L Ma, PL Nagy, Y Natkunam, RA Warnke, RF Dorfman, DA Arber.

TNFRSF6 (Fas antigen) mutations in patients with sinus histiocytosis with massive

lymphadenopathy (Rosai-Dorfman disease). Blood 104:2389, 2004, ASH.

Tracy George 20

4. S Kim, R Lowsky, I Pereira, DA Arber, TI George. Pathologic correlates in bone marrow

associated with acute graft-vs-host disease following hematopoietic stem cell

transplantation. Modern Pathology 18:237A, 2005, USCAP.

5. MO Leavitt, JE Wrede, H Vogel, AM Cherry, DA Arber, TI George. Primary CNS Low-

Grade B-cell lymphoma: a case series with FISH analysis. Modern Pathology 18:239A,

2005, USCAP.

6. P Khuu, MC Wei, A Bruckner, TI George, J Zehnder, NJ Lacayo, M Jeng. Recalcitrant

cutaneous Langerhans cell histiocytosis in a child with T-cell acute lymphoblastic

leukemia. Histiocyte Society, 2006.

7. I Mattoch, TI George, C Kong. Cytospin Is Superior to ThinPrep for the Detection of

CSF Involvement by Hematolymphoid Malignancies. Modern Pathology 20:76A,

supplement 2, 2007, USCAP.

8. L Pate, Y Natkunam, TI George. CXCL13 Expression Patterns in B-Cell Non-Hodgkin

Lymphomas. Modern Pathology 20: 255A, supplement 2, 2007, USCAP.

9. TI George, K Seo, S Blais, DA Arber. Detection of JAK2 Kinase Mutations in Formalin-

Fixed Spleen, a Comparison of Two Molecular Assays. Modern Pathology 20: 240A-

241A, supplement 2, 2007, USCAP.

10. TI George, DA Arber, E Hsi, A Linder, A Ruddell, C Lanza, T Graubert and J Gotlib.

Bone marrow findings after KIT tyrosine kinase inhibitor midostaurine (PKC412)

therapy in aggressive systemic mastocytosis (ASM). Modern Pathology 21:254A, 2008,

USCAP.

11. TI George, E Ballabio, JC Paterson, SA Pileri, M-L Hansmann, W Klapper, T Longacre,

RB West, M van de Rijn, J Boultwood, J Wainscoat, T Marafioti. ECA39/BCAT1, a

germinal centre-associated marker expressed in B-cell and T-cell lymphomas. J

Hematopathol 1:249, 2008, European Association for Haematopathology.

12. AC Logan, R Su, TI George, HE Kohrt, BC Medeiros, AA Alizadeh. High Risk of Early

Mortality in Adult Patients with Acquired Hemophagocytic Lymphohistiocytosis. Blood

114: 1359, 2009, ASH.

13. MA Bautista-Quach, C Wong, S Moore, B Glader, TI George. A Case of Hereditary

Elliptocytosis with Concomitant Glucose-6-Phosphate Dehydrogenase Deficiency.

Archives of Pathology and Laboratory Medicine 134:1313, 2010, CAP.

14. MA Bautista-Quach, C Wong, B Glader, TI George. Episodic Hemolytic Anemia

Secondary to Unstable Hemoglobin Seattle: The Importance of Thorough Investigation

for Proper Diagnosis. Archives of Pathology and Laboratory Medicine 134:1320, 2010,

CAP.

15. A Deucher, TI George, J Yu, Z Qi, A Cherry, J Etzell. BCL6 expression in B-cell

lymphoblastic leukemia correlates strongly with the 1;19 translocation. Am J Clin Pathol

134(31):10, 2010, ASCP.

16. J Gotlib, DJ DeAngelo, TI George, C Corless, A Linder, C Langford, C Dutreix, S

Gross, Z Nikolova, T Graubert. KIT Inhibitor Midostaurin Exhibits A High Rate of

Clinically Meaningful and Durable Responses in Advanced Systemic Mastocytosis:

Report of a Fully Accrued Phase II Trial. Blood 116:316, 2010), ASH

17. A Arredondo, C Jennings, L Shier, U Sundram, J Gotlib, TI George. CD30 expression in

mastocytosis. Modern Pathology 24:285A (2011).

Tracy George 21

18. A Arredondo, C Jennings, U Sundram, ZS Lu, TI George. Expression of 2D7, a unique

marker of basophils, in myeloproliferative neoplasms. Modern Pathology 24:286A, 2011,

USCAP.

19. JR Gotlib, H Kluin-Nelemans, MJ Mauro, O Hermine, EO Hexner, JH Lipton, FT Awan,

Z. Nikolova, SH Gross, C Dutreix, B Dharan, TI George, HP Horny, C Akin, K

Hartmann, P Valent, A Reiter. A global phase II, single arm, open-label study to

determine the efficacy of midostaurin in patients with aggressive systemic mastocytosis

(ASM) or mast cell leukemia (MCL) +/- an associated hematological clonal non-mast cell

lineage disease (AHNMD). ASCO 29:(suppl; abstr TPS200) 2011.

20. S Geaghan, A Nava, TI George. CD64 quantitation on neutrophils using a conventional

hematology analyzer for adult and pediatric specimens in a tertiary care hospital and

clinics setting. International Journal of Laboratory Hematology 33:60, supplement 1,

2011, ISLH.

21. A Arredondo, C Jennings, L Shier, U Sundram, J Gotlib, TI George. CD30 expression in

systemic and cutaneous mastocytosis. European Competence Network in Mastocytosis,

Istanbul Turkey, 2011.

22. CA Kunder, DJ Deangelo, JR Gotlib, G Gitana, SK Atwater, TI George. Loss of CD25

expression in advanced systemic mastocytosis patients treated with Midostaurin

(PKC412). Modern Pathology 25 Supplement 2: 349A, 2012, USCAP.

23. JR Gotlib, H Kluin-Nelemans, MJ Mauro, O Hermine, EO Hexner, JH Lipton, FT Awan,

Z. Nikolova, SH Gross, C Dutreix, B Dharan, TI George, HP Horny, C Akin, K

Hartmann, P Valent, A Reiter. KIT Inhibitor Midostaurin in Patients with Advanced

Systemic Mastocytosis: Results of a Planned Interim Analysis of the Global

CPKC412D2201 Trial. Blood 120(21):799, 2012, ASH.

24. J McNaughton, J Hughes, J Andrews, TI George, C Bergero, K Pyke-Grimm, S Galel, C

Gonzales, LT Goodnough, M Fontaine. Hemoglobinuria and Mechanical Hemolysis

Associated with Red Blood Cell Transfusion in Pediatric Patients. Blood 120(21):3429,

2012, ASH.

25. RC Johnson, BA Martin, JR Gotlib, DA Arber, TI George. Frequency of Systemic

Mastocytosis in Chronic Myelomonocytic Leukemia - A Single Institutional Study

Modern Pathology 26 Supplement 2: 336A, 2013, USCAP.

26. BA Martin, RC Johnson, JR Gotlib, DA Arber, TI George. Occult Mastocytosis in AML

with Inv(16) and Therapy-Related AML. Modern Pathology 26 Supplement 2: 344A,

2013, USCAP.

27. JR Gotlib, HC Kluin-Nelemans, TI George, C Akin, K Sotlar, O Hermine, F Awan, E

Hexner, M Mauro, R Morariu, M Squier, M Villeneurve, F Emery-Salbert, J Coombs, K

Hartmant, HP Horny, P Valent, A Reiter. Durable Responses and Improved Quality Of

Life With Midostaurin (PKC412) In Advanced Systemic Mastocytosis (SM): Updated

Stage 1 Results Of The Global D2201 Trial. Blood 122:106, 2013, ASH.

28. D Chabot-Richards, AZ Mahmoud, D Czuchlewski, MA Vasef, J Maxson, J Tyner, D

Arber, J Gotlib, TI George. Clinical, Laboratory, and Morphologic Features of Myeloid

Malignancies with CSF3R and SETBP1 Mutation. Modern Pathology 27 Supplement

2:340A, 2014, USCAP.

29. AZ Mahmoud, JM Gale, D Chabot-Richards, T George, JE Maxson, JW Tyner, M

Vasef. Detection of CSF3R Proximal Membrane Mutation Using PCR Followed by High

Tracy George 22

Resolution Melting Curve Analysis. Modern Pathology 27 Supplement 2:360A, 2014,

USCAP.

30. AZ Mahmoud, DR Czuchlewski, QY Zhang, CS Wilson, C Sever, A Bakhirev, D Zhang,

N Steidler, KK Reichard, HE Nelson, T George, K Foucar MA Vasef. MYC Protein

Expression by Immunohistochemistry in High Grade B-Cell Lymphomas: Concordance

Rate among Hematopathologists. Modern Pathology 27 Supplement 2:360A, 2014,

USCAP.

31. KA Rizzo, KT Bradley, DR Czuchlewski, SL Perkins, JE Etzell, TI George. Proficiency

Testing for Bone Marrow Aspirate Smears using Virtual Slides, a College of American

Pathologists Experience. International Journal of Laboratory Hematology 36

Supplement 1:7, 2014, ISLH.

32. AZ Mahmoud, D Chabot-Richards, TI George, M Vasef. SETBP1 Mutations in Myeloid

Malignancies: A Retrospective Study Using PCR Followed By High Resolution Melting

Curve Analysis. Association of Molecular Pathology, 2014.

33. B Dimos, E Hatch, T George, D Lidke. Quantum Dot Immunohistochemistry for Protein

Detection in Systemic Mastocytosis. University of New Mexico Undergraduate Pipeline

Network Summer Research Session, 7/31/2014.

34. D Babu, D Czuchlewski, DA Arber, TI George. P53 Immunohistochemical Expression Is

Specific for MDS and MDS/MPN in Bone Marrow. Modern Pathology 2015; 28, supplement

2:337A, USCAP.

35. E Hatch, D Lidke, TI George. Quantum Dot IHC as a Method to Characterize Mast Cells,

Modern Pathology 2015; 28, supplement 2:514A-515A, USCAP.

36. DP Steemsa, M Abedi, R Bejar, CR Cogle, K Foucar, G Garcia-Manero, TI George, D

Brinblatt, R Komrokji, J Maciejewski, DA Pollyea, GJ Roboz, M Savona, B Scott, M

Sekeres, MA Thompson, MM Sugrue, AS Swern, M Nifenecker, H Erba. CONNECT

MDS and AML: the Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia

(AML) Disease Registry. 13th International Symposium on Myelodysplastic Syndromes

2015, Leukemia Research Journal 2015.

37. R Falahati, J Bright, A Dorenbaum, C Bebbington, N Tomasevic, D Lidke, TI George, J

Gotlib. A recombinant antibody to Siglec-8 shows selective ADCC activity against mast

cells from systemic mastocytosis patients. Blood 2015, ASH.

38. DA Arber, NE Thomas, R Souers, JA Tworek, RE Nakhleh, TI George. Baseline

evaluation of testing of acute leukemia samples: results of a CAP/CDC guidelines metric

expert panel survey. USCAP (2016).

39. C Villa, TI George, K Foucar, D Chabot-Richards. Pathologist-driven test utilization in

hematopathology. USCAP (2016).

40. SA Wang, W Tam, A Tsai, DA Arber, RP Hasserjian, JT Geyer, T George, DR

Czuchlewski, K Foucar, HJ Rogers, E Hsi, B Rea, A Bagg, P Dal Cin, T Kelley, S

Verstovsek, C Bueso-Ramos, A Orazi. Targeted next generation sequencing (NGS) of

chronic eosinophilic leukemia, not otherwise specified (CEL, NOS) and of idiopathic

hypereosinophilic syndrome (HES). USCAP (2016).

41. HJ Rogers, ED Hsi, SA Wang, CE Bueso-Ramos, D Lubin, A Bagg, DP Cherukuri, TI

George, LC Peterson, YC Liu, S Mathew, A Orazi, RP Hasserjian. Most myeloid

neoplasms with deletion of chromosome 16q are distinct from acute myeloid leukemia

with inv(16)(p13q22). USCAP (2016).

Tracy George 23

42. M Geeze, E Hatch, C Martin, S Perkins, K Hartmann, P Valent, J Gotlib, D Lidke, T

George. PD-1/PD-L1 are novel therapeutic targets for mastocytosis. USCAP (2016).

43. D Bustamante, B Coffman, J Gale, M Vasef, T George. Absence of LEF1 Expression in

Atypical CLL/SLL Unmasks Other B-cell Lymphomas. USCAP (2016).

44. TG Miley, MA Sekeres, ML Slovak, RS Komorkji, AA Ali, ER Parks, SM Ziemnik, TI

George. Determining educational needs in myelodysplastic syndrome. USCAP (2016).

Current Grant and Contract Funding:

12/15/2014 – 12/31/2017 Funder: Celgene

AML/MDS Disease Registry

Role: Central Pathology Review; 2% salary support

9/12/2013 – 12/31/2016 Funder: Seattle Genetics

Title: A pilot study of brentuximab vedotin (SGN-35) in CD30-

positive systemic mastocytosis with or without an associated

hematological clonal non-mast cell lineage disease (AHNMD)

Role: Pathologist; 1% salary support; PI: J Gotlib

5/20/2009 - 2017 Funder: Novartis, Inc.

Title: Laboratory Services Agreement PKC412D2201, SPO#44250

(originally Stanford, now UNM/TriCore), International Clinical

Trial of PKC412 for Aggressive Forms of Systemic Mastocytosis,

in which Dr. George is the Pathologist for N. American Trial

Patients

Role: Pathologist; 1% salary support; PI: J. Gotlib

Past Grant and Contract Funding:

6/1/2014 - 9/30/2015 Funder: Allakos, Inc.

Title: Human mast cells and mast cell disease: clinical, phenotypic,

cell signaling, and genetic correlates.

Role: PI; 5% salary support

2/11/2005-2/28/2013 Funder: Novartis, Inc.

Title: PKC412A2213; A Single Arm, Phase II, Open-label Study

to Determine the Efficacy of Twice Daily Oral Dosing of PKC412

Administered to Patients with Aggressive Systemic Mastocytosis

(ASM) and Mast Cell Leukemia (MCL) +/- Associated

Hematological Non-Mast Cell Disorders

Role: Co-Investigator (Principal Investigator: J. Gotlib)

2005 - 2007 Funder: Stanford University Medical Scholars Research Program

Title: Detection of Novel Cytogenetic Abnormalities in Low Grade

B-cell Lymphomas

Role: PI

2004 - 2011 Funder: Novartis, Inc.

Title: Protocol ID#CSTI571AUS151; Phase II Clinical Trial to

Evaluate the Effectiveness of Gleevec (imatinib mesylate) in

Patients with Hypereosinophilic Syndrome

Role: Co-Investigator (Principal Investigator: J. Gotlib)

2003 - 2005 Funder: Stanford University Department of Pathology

Tracy George 24

Title: Detection of PAX5 Abnormalities in Low Grade B cell

Lymphomas by FISH analysis

Role: PI

2003 - 2005 Funder: Stanford University Medical Scholars Research Program

Title: Detection of Lymphoma-associated Cytogenetic

Translocations by FISH Analysis

Role: Primary Advisor (Principal Investigator: D. Arber)

Tracy George 25

Mentoring of faculty in scholarship:

Devon Chabot-Richards, MD, UNM faculty, 2014- current, mentoring in scholarship, monthly

meetings, facilitated an introduction to the College of American Pathologists HLA Committee-

she is now a member, Medical Director of HLA Lab, TriCore Laboratories

D Chabot-Richards, TI George. Leukocytosis. International Journal of Laboratory

Hematology 2014;36(3):279-88. Epub 2014 Apr 18.

D Chabot-Richards and TI George. White Blood Cell Counts: Reference Methodologies.

In: Brugnara C, Kratz A (editors). Automated Cell Counters: State of the Art and New

Directions. Clinics in Laboratory Medicine 35(1):11-24 (2015).

D Chabot-Richards, AZ Mahmoud, D Czuchlewski, MA Vasef, J Maxson, J Tyner, D

Arber, J Gotlib, TI George. Clinical, Laboratory, and Morphologic Features of Myeloid

Malignancies with CSF3R and SETBP1 Mutation. Modern Pathology 27 Supplement

2:340A (2014).

AZ Mahmoud, JM Gale, D Chabot-Richards, T George, JE Maxson, JW Tyner, M

Vasef. Detection of CSF3R Proximal Membrane Mutation Using PCR Followed by High

Resolution Melting Curve Analysis. Modern Pathology 27 Supplement 2:360A (2014).

Sara Koenig, MD, UNM faculty, 2013- 6/2015, mentoring in scholarship, monthly meetings,

outcomes: enrolled in MBA program, invited to join College of American Pathologists’ Quality

Practices Committee, monitoring progress on academic manuscripts

Tracy George 26

Teaching/Education:

Undergraduate medical student mentoring:

Joanna Wrede, Stanford Medical School Medical Scholars Program, 2003-2005, Detection of

Lymphoma-associated Cytogenetic Translocations by FISH Analysis, Primary Advisor:

Tracy George; Stanford University Department of Pathology, Detection of PAX5

Abnormalities in Low Grade B cell Lymphomas by FISH analysis, PI: Tracy George;

I worked with Joanna Wrede before medical school when she was a research

assistant in my lab. She was accepted at Stanford for medical school and we

continued to work together in the Stanford Medical School Medical Scholars

Program. She was accepted into a residency program in Pediatric Neurology at

the University of Washington.

TI George, JE Wrede, CD Bangs, AM Cherry, RA Warnke, DA Arber. Low

grade B-cell lymphomas with plasmacytic differentiation lack PAX5 gene

rearrangements. J Molec Diagnostics 2005;7(3):346-351.

JE Wrede, U Sundram, S Kohler, AM Cherry, DA Arber, TI George.

Fluorescence in situ hybridization investigation of cutaneous lesions in acute

promyelocytic leukemia. Modern Pathology 2005;18(12):1569-1576 .

Angela McGuire (Arredondo), Stanford Medical School Scholarly Concentration, 2005 –

2007, Detection of Novel Cytogenetic Abnormalities in Low Grade B-cell Lymphomas,

PI: Tracy George;

Angela McGuire was one of my students in the Hematology course in medical

school where I was the co-director of the course and a small group leader. She

worked with me while in medical school and was accepted into the Stanford

Pathology Residency program where she continued to work with me. She was

accepted into a Forensics Pathology program in New York.

AR Arredondo, J Gotlib, L Shier, B Medeiros, K Wong, A Cherry, C Corless,

DA Arber, P Valent, TI George. Myelomastocytic leukemia versus mast cell

leukemia versus systemic mastocytosis associated with acute myeloid leukemia: a

diagnostic challenge. American Journal of Hematology 2010;85(8):600-6.

A Arredondo, C Jennings, L Shier, U Sundram, J Gotlib, TI George. CD30

expression in mastocytosis. Modern Pathology 24:285A (2011).

A Arredondo, C Jennings, U Sundram, ZS Lu, TI George. Expression of 2D7, a

unique marker of basophils, in myeloproliferative neoplasms. Modern Pathology

24:286A (2011).

A Arredondo, C Jennings, L Shier, U Sundram, J Gotlib, TI George. CD30

expression in systemic and cutaneous mastocytosis. European Competence

Network in Mastocytosis, Istanbul Turkey (2011).

Mary Geeze, University of New Mexico School of Medicine, 2015-2018, PD1 and PD1L

expression in mastocytosis, PI: Tracy George, Co-PI: Diane Lidke

M Geeze, E Hatch, C Martin, S Perkins, K Hartmann, P Valent, J Gotlib, D

Lidke, T George. PD-1/PD-L1 are novel therapeutic targets for mastocytosis.

USCAP (2016).

Pre-baccalaureate student mentoring:

Brad Dimos, Baylor University, Undergraduate Pipeline Network, 6/2014-8/2014

Tracy George 27

B Dimos, E Hatch, T George, D Lidke. Quantum Dot Immunohistochemistry for

Protein Detection in Systemic Mastocytosis. University of New Mexico

Undergraduate Pipeline Network Summer Research Session, 7/31/2014.

Chandler Livingston, University of New Mexico, 5/2015-8/2015

Bone marrow quality improvement project

Classroom, laboratory teaching, and tutoring:

2015, Hematology Course, University of New Mexico School of Medicine

Anemias 1 & 2, December 2015

Acute Leukemia, December 2015

Cases, Lab teaching, December 2015

2014, Genetics and Neoplasia Course, University of New Mexico School of Medicine

Anemias- part I, November 3, 2014

Acute and Chronic Leukemias, November 5, 2014

Tutor for 8 medical students

Small group leader for ~30 medical students, Hematology case presentations, November

4-5, 2014

2006-2012, Co-director of Hematology section of Human Health & Diseases 223, Stanford

University School of Medicine

Introduction to Hematopoiesis Lecture

Benign Neutrophil Disorders and Acute Myeloid Leukemia Lecture

Benign Myeloid Disorders Lecture

Malignant Myeloid Disorders Lecture

Pathology Review

Small group leader for ~8-10 medical students:

Anemia Laboratory

Hemolysis Laboratory

Bone Marrow Failure Laboratory

Lymphoid Laboratory

Myeloid Laboratory

Hemostasis Laboratory

Thrombosis Laboratory

Transfusion Laboratory

2003, Pathology 230A, Stanford University School of Medicine

Small group tutor: Pathology Oral Examination, Neoplasia Laboratory, Hematology

Laboratory

Neoplastic Disorders of the Peripheral Blood & Bone Marrow Lecture

2004, INDE 216, Stanford University School of Medicine

Journal Club for First Year Medical Students

Resident and fellow mentoring:

Christine Cesca, MD, Stanford fellow and clinical instructor, 7/2003-6/2005

Eloisa Fuentes, MD, Stanford resident and fellow, 7/2003-6/2008

Amy Ly, MD, Stanford resident and fellow, 7/2005-6/2009

Caroline Temmins, MD, Stanford resident and fellow, 7/2007-6/2010

Renuka Agrawal, MD, Loma Linda pathology resident, CAP Foundation Award for 1

month visiting rotation/research in RBC Special Studies Laboratory, 2008

Tracy George 28

Marnelli Bautista, MD, Loma Linda pathology resident, ASCP Subspecialty Award for 1

month visiting rotation/research in RBC Special Studies Laboratory, 2010

Ryan Johnson, MD, Stanford resident, 7/2010-12/2012

Marisa Juntilla, MD, PhD, Stanford resident, 7/2011-12/2012

Alana Shain, MD, Stanford resident, 7/2011-12/2012

Daniel Cloetin, MD, Stanford resident, 7/2012-12/2013

Amer Mahmoud, MD, UNM fellow, 1/2013-6/2013

Stella Wenceslao, MD, UNM fellow, 1/2013-6/2013

Elizabeth Chastain, MD, UNM fellow, 1/2013-6/2013

Frank Moore, MD, UNM fellow, 1/2013-6/2013

Julia Boncher, MD, UNM fellow, 7/2013-6/2014

Nikki Steidler, MD, UNM fellow, 7/2013-6/2014

Ben Wetzel, MD, UNM fellow, 7/2013-6/2014

Dorothy Wong, MD, UNM fellow, 7/2013-6/2014

Daniel Babu, MD, UNM fellow, 7/2014-6/2015

Anthony Halfacre, MD. UNM fellow, 7/2014-6/2015

Michael Reyes, MD, UNM fellow, 7/2014-6/2015

Nathan Thompson, MD, UNM fellow, 7/2014-6/2015

Daniel Bustamante, MD, UNM fellow, 7/2015-6/2016

David Lynch, MD, UNM fellow, 7/2015-6/2016

Melody Harrison, MD, UNM fellow, 7/2015-6/2016

Celina Villa, MD, UNM fellow, 7/2015-6/2016

Resident advisor:

Casey Bitting, UNM resident, 7/2014-6/2018

Benjamin Ramos, UNM resident, 7/2014-6/2018

Joshua Routh, UNM resident, 7/2014-6/2018

Nathan Tokuda, UNM resident, 7/2014-6/2018

Resident and fellow teaching:

University of New Mexico

Hematopathology Fellowship Director, 1/2013 – present, 1 year fellowship

Chair, Program Evaluation Committee, 5/2014 – present, Hematopathology fellowship

Member, Clinical Competency Committee, 4/2014 - present, Hematopathology fellowship

Chair, Clinical Competency Committee, 7/2013-12/2014, 10/2015 – present,

Pathology Residency Program

Member, Clinical Competency Committee, 1/2015 - present, Pathology Residency Program

Member, Program Evaluation Committee, 4/2014 – 9/2015, Pathology Residency Program

Lecturer, Pathology Didactic Series, 2013-2015

Principles of Automated Hematology

Reactive Lymphadenopathies

Lymphomas

Anemias

Myeloproliferative Neoplasms 1 and 2

Lecturer, Hematology/Oncology Lecture Series, University of New Mexico Cancer Center

Myelodysplastic Syndromes, 7/2013

2013 Update on High Grade Non-Hodgkin Lymphomas and Hodgkin Lymphoma, 9/2013

Tracy George 29

Myelodysplastic Syndromes, 7/2014

2014 Update on Non-Hodgkin Lymphoma, 9/2014

Unknown conferences for Hematopathology Trainees

Myeloproliferative Neoplasms, 6/2013

Myeloproliferative Neoplasms, 8/2013

Lymphomas 1, 2/2014

Lymphomas 2, 2/2014

Lymphomas 1, 6/2014

Lymphomas 2, 6/2014

Lymphomas 1, 10/2014

Leukocytosis, 11/2014

Lymphomas 1, 8/2015

Myeloproliferative Neoplasms, 11/2015

Department of Pathology Seminar Series

The Diagnosis of Mastocytosis, 2/2014

Tumor Marker Conference

2013 Updates from the Society for Hematopathology-part 1, 11/2013

Coordination of Citywide Conference, a joint UNM-TriCore Conference involving UNM and

community hematologists/oncologists where trainees present, 2013-present

Stanford

Lecturer, Pathology Resident Didactic Lecture series, Stanford University School of Medicine, 2003-

2012

Myeloproliferative Neoplasms

Automated Hematology

Myelodysplastic Syndromes

CSF and Body Fluids

Immunodeficiency-associated Lymphoproliferative Disorders

New Insights into Reactive Lymphadenopathies

Diagnostic Hematology- parts 1 and 2

Reactive Lymphadenopathy- parts 1 and 2

Lecturer, Current Concepts Lecture series, Department of Pathology, 2003-2010

How to Give an Effective Pathology Presentation

Hematopathology small group sessions for residents/fellows, 2004-2012

Lessons from the Peripheral Blood Smear

Peripheral Blood Smear-Anemia & RBC Abnormalities

Hematopathology Microscope Conference

Myeloproliferative Neoplasms

Reactive Lymphadenopathy

Gross room small group sessions for residents/fellows, Department of Pathology

Proper Handling of Hematopoietic Tissues, 2004-2012

Adult Hematology/Hematopathology Monthly Conference Series, co-founded 2006 with Jason Gotlib,

MD, Stanford University School of Medicine, 2006-2012

Tracy George 30

Other teaching:

In-services for Medical Technologists, Stanford University Clinical Laboratory, 2002-2012

Coordinator, Core Lab Lecture Series for Medical Technologists, Stanford University Clinical

Laboratory, 2006-2011

Tracy George 31

Present patient care activities:

Senior Director of Clinical Affairs, Department of Pathology, UNM

Hematopathology Division Chief, Department of Pathology, UNM

Medical Director, Genetics and Cytometry Laboratories, TriCore Reference Laboratories

University Hospital Hematopathology Service: bone marrows, lymph nodes/lymphoid tissues, peripheral

blood smears, body fluids, flow cytometry, integrated reports, review of outside biopsies on patients

being treated at UNM

Hematopathology Consultation Service: bone marrows/lymph nodes/lymphoid tissue cases sent from all

over the country for our consultation and diagnosis, flow cytometry cases outside of UNM

Cytogenetics and FISH for leukemias and lymphomas

Second review of hematopathology cases

Core blood review for TriCore Reference Laboratories

Hematopathology call for UNM and TriCore Reference Laboratories- rotated among faculty so that 24/7

coverage is provided for UNM and TriCore, includes weekend service at TriCore

Adult tumor board

Pediatric tumor board

Past patient care activities:

Diagnosis of hematopathology tissues (bone marrows, lymph nodes), body fluids,

peripheral blood smears and flow cytometry.

06/2012 – 12/2012 Interim Associate Director of Pediatrics, Anatomic Pathology and

Clinical Laboratories, Lucile Packard Children’s Hospital

Coordinating all pathology and laboratory services for the

children’s hospital

06/2012 – 12/2012 Medical Director, Mary Johnson Pediatric Ambulatory Care Center Laboratory,

Lucile Packard Children’s Hospital

Automated hematology, chemistry, urinalysis, blood smears, phlebotomy

Staff ~5, 1 supervisor

03/2011 – 12/2012 Medical Director, Bass Center Laboratory for Childhood Cancer and Blood

Diseases, Lucile Packard Children’s Hospital

Automated hematology, blood smears

Staff ~2, 1 supervisor

03/2011 – 05/2012 Co-Medical Director, Mary Johnson Pediatric Ambulatory Care Center

Laboratory, Lucile Packard Children’s Hospital

01/2009 - 12/2012 Director, Clinical Hematology Laboratory

Stanford Hospital and Clinics and Lucile Packard Children’s Hospital

Peripheral blood smears, Bone marrows, Automated hematology, Body fluids, Urinalysis

Staff ~50, 3 supervisors, 1 operations manager

01/2006 - 12/2012 Associate Director, RBC Special Studies Laboratory

Stanford Hospital and Clinics and Lucile Packard Children’s Hospital

Hemoglobin electrophoresis, HPLC, RBC enzymes, osmotic fragility

Staff ~3, 1 operations manager

01/2004 – 07/2008 Medical Director, Stanford Clinical Laboratories Satellite Laboratory at

2585 Samaritan Blvd, San Jose, CA

Hematology, Coagulation, Chemistry, Urinalysis, Phlebotomy

Tracy George 32

Staff ~7, 2 supervisors, 1 operations manager

09/2002 – 01/2009 Associate Director, Clinical Hematology Laboratory

Stanford Hospital and Clinics and Lucile Packard Children’s Hospital

University, SOM, HSC extradepartment duties

University of New Mexico

10/2014 – 9/2015 Member, Search Committee for Hematologic Malignancies Faculty, UNM

Cancer Center

8/2013 - present Associate Member, University of New Mexico Cancer Center

Stanford

2011 - 2012 Member, Disease Management Group, Hematology, Comprehensive

Cancer Center, Stanford University Medical Center

2011 - 2012 Member, Blood Transfusion Clinical Effectiveness Task Force, Stanford

University Medical Center

2010 - 2011 Alternate Senator, Faculty Senate, Stanford University School of Medicine

2007 - 2011 Admissions Committee, interviewer, Stanford University SOM

2006 - 2009 Senator, Faculty Senate, Stanford University SOM

2005 - 2012 Associate Member, Comprehensive Cancer Center, Stanford University

Medical Center

University, SOM, HSC, department committees:

University of New Mexico/TriCore Reference Laboratories

7/2015 – present Medical Director, Genetics and Cytometry Laboratories, TriCore

4/2015 - present Innovation Council, TriCore Laboratories

4/2015 – present Pathology Leadership Group, TriCore Laboratories

2014 - present Executive committee, Department of Pathology

1/2014 - 6/2014 Chair, Faculty Incentive Based Compensation Initiative Committee, Dept

of Pathology

2013 Chair, Promotion Committee for David Czuchlewski, MD

2013 Member, Promotion Committee for Qian-Yun Zhang, MD, PhD

2013 - 7/2014 Hematopathology/Clinical Pathology Workgroup Chair, Test Utilization

Committee, TriCore Laboratories

2013 - 7/2014 Member, Test Utilization Committee/Workgroup, TriCore Laboratories

8/2013 - 6/2014 Member, BizQual Committee, TriCore Laboratories

8/2013 - 6/2014 Member, External Workgroup, BizQual Committee, TriCore Laboratories

8/2013 - present Member, Anatomic Pathology & Oncology Committee, TriCore Labs

9/2013 - 6/2014 Chair, Telepathology and Imaging Workgroup, TriCore Laboratories

9/2013 -1/2014 Member, IHC Workgroup, TriCore Laboratories

10/2013 Physician member, TriCore CEO Search Committee

11/2013 - 10/2014 Chair, Research Workgroup, TriCore Laboratories

Stanford

2010 - 2011 Laboratory Leadership Group, Stanford Hospital and Clinics, Clinical

Laboratory

2010 - 2011 Business owner, Laboratory Business Intelligence System (Rhodes)

Project Team

Tracy George 33

2009 - 2010 Business owner, Sunquest QC Utilization Project, Stanford Hospital and

Clinics, Clinical Laboratory

2009 Business owner, Autoverification Project, Stanford Hospital and Clinics,

Clinical Laboratory

2008 Search Committee for Associate Medical Director of Microbiology

2008 Business Owner, Laboratory Planning Project, Stanford Hospital and

Clinics, Clinical Laboratory

2005 - 2007 Leadership Group, Department of Pathology, Stanford University SOM

2004 - 2008 Residency and Fellowship Committee, Department of Pathology, Stanford

University SOM

2002 - 2005 Point of Care Testing Committee, Stanford Hospital and Clinics, Clinical

Laboratory

2002 Pediatric Laboratory Oversite Committee, Stanford Hospital and Clinics,

Clinical Laboratory