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Conference 2015
Trends in Central Nervous System Malignancies
ADVANCE PROGRAMME
The future of cancer therapy
27 – 28 MARCH 2015 ISTANBUL, TURKEY
Organised by:
supported byTurkish Neuro-Oncology Society
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EORTC-EANO-ESMO 2015: SAVE THE DATES
Housing Reservation Closes25 November 2014: Hilton Hotel
25 December 2014: Other Hotels
Abstract Submission Opens 12 December 2014
Early Rate Registration Closes 9 January 2015
Abstract Submission Closes 12 February 2015
Fellowship Grant Application Closes 12 February 2015
Regular Rate Registration Closes 24 February 2015
Desk Rate Only as of 25 February 2015
CONFERENCE COMMITTEE
ORGANISING COMMITTEE
Martin J. van den Bent (EORTC)Riccardo Soffietti (EANO)Michael Weller (ESMO)
EORTC REPRESENTATIVES
Roger Stupp (EORTC)Wolfgang Wick (EORTC)
EANO REPRESENTATIVES
Ufuk AbaciogluChristine Marosi
ESMO REPRESENTATIVES
Jörg TonnAlba Brandes
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CONFERENCE SECRETARIAT & VENUE
SECRETARIAT
ECCO-the European Cancer Organisation Avenue E. Mounier 83B-1200 BrusselsBelgiumTel: +32 (0)2 775 02 01Fax: +32 (0)2 775 02 00Email: [email protected]/EEE2015
VENUE
Hilton Istanbul Bosphorus & Hilton Istanbul Convention & Exhibition Centre Cumhuriyet Caddesi Harbiye 34367, Istanbul TurkeyTel: +90 212 315 6000 Fax: +90 212 240 4165http://bit.ly/EEE2015venue
CONTACT US
Scientific Programme
Samira Essiaf Tel: +32 (0)2 775 02 49 [email protected]
Registrations
Emilie Fillod Tel: +32 (0)2 775 02 47 [email protected]
Congress Operations
Adline Lewuillon Tel: +32 (0)2 775 02 40 [email protected]
Allegra Roccato Tel: +32 (0)2 775 29 35 [email protected]
Corporate Marketing
Bruno De Man Tel: +32 (0)2 775 02 04 [email protected]
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TABLE OF CONTENTS
WELCOME LETTER 5
SCIENTIFIC PROGRAMME 6
Detailed Advance Programme: Friday 27 March 2015 6
Detailed Advance Programme: Saturday 28 March 2015 8
CALL FOR ABSTRACTS 10
Abstract Policies & Regulations 10
Abstract Preparation & Submission 11
Abstract Selection Process 11
REGISTRATION 12
Individual Registration 12
Group Registration 13
FELLOWSHIP GRANTS 15
GENERAL INFORMATION 16
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WELCOME LETTER
Dear Colleagues,
Following on from the EORTC-EANO-ESMO Conference in 2015 in Prague, we are very pleased to announce on behalf of the European Organisation for Research and Treatment of Cancer (EORTC) Brain Tumour Group, the European Association of Neuro-Oncology (EANO), and the European Society for Medical Oncology (ESMO), the fourth in the biennial series of EORTC-EANO-ESMO Conferences: Trends in Central Nervous System Malignancies. This conference, supported by the Turkish Neuro-Oncology Society, will be held in Istanbul, Turkey on 27-28 March 2015.
The main focus of the joint EORTC-EANO-ESMO Conference is to improve the neuro-oncology field, accelerate the translation of cutting edge discovery at the clinical level, and further promote international scientific cooperation, debate and exchange.
Adopting a highly multidisciplinary approach, EORTC-EANO-ESMO 2015 draws an attendance of neuro-surgeons, neurologists, neuro-pathologists, medical oncologists, and radiation oncologists sharing the common goal of advancing the management, treatment and care of patients with central nervous system tumours, including gliomas, brain and spine metastatic disease, meningioma, CNS lymphoma and primary spinal cord tumours.
Through a series of plenary sessions, workshops and breakout sessions, Trends in Central Nervous System Malignancies will provide a rigorous review of novel therapies, agents and combination strategies, as well as report on the very latest findings in basic and clinical research. The event Programme will focus on the latest trends in the field, explore much debated controversies and review novel clinical developments.
Last, but by no means least, our host city Istanbul, known for its breath-taking architecture with its wealth of monuments and being a mosaic of many cultures and civilisations, will provide yet further reason for joining us for the fourth EORTC-EANO-ESMO 2015 Conference.
We look forward to welcoming you all for what promises to be an outstanding educational event: Trends in Central Nervous System Malignancies, 27-28 March 2015.
Martin J. van den Bent Riccardo Soffietti Michael WellerEORTC EANO ESMO
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SCIENTIFIC PROGRAMMEDETAILED ADVANCE PROGRAMME: FRIDAY 27 MARCH 2015
08:30 WELCOME & INTRODUCTION
SESSION I: BASIC DEVELOPMENTS IN GLIOMAModerator: To be Confirmed
08:35 Clonal diversity in glioblastoma: Is it clinically relevant?Speaker: Colin Watts (United Kingdom)
09:00 Promising molecular targets in glioblastomaSpeaker: To be Confirmed
09:25 ATRX and TERT mutations in diffuse gliomas: Fundamental and practical implicationsSpeaker: Tarik Tihan (United States)
09:50 Discussion (15’)
10:05 Coffee Break (25’)
SESSION II: DIAGNOSIS AND PROGNOSIS: DIAGNOSIS 2.0?Moderator: To be Confirmed
10:30 How much molecular diagnostics is essential for diagnosis and treatment of gliomas in 2015?Speaker: Guido Reifenberger (Germany)
10:55 Standardisation of imaging in neuro-oncology Speaker: To be Confirmed
11:20 Clinical impact of Next Generation Sequencing in neuro-oncologySpeaker: Michael Weller (Switzerland)
11:45 Discussion (15’)
12:00-13:00 Lunch
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SESSION III: MANAGEMENT OF GRADE 2 AND 3 GLIOMAModerator: To be Confirmed
13:00 Is tumour grade still relevant? A molecular perspectiveSpeaker: Pim French (The Netherlands)
13:20 Management of low-grade gliomas: Update on the recent trials Speaker: Martin van den Bent (The Netherlands)
13:40 Oligodendroglioma with 1p/19q co-deletion: What is the next question?Speaker: Marc Sanson (France)
14:00 Discussion (15’)
SESSION IV: MANAGEMENT OF GLIOBLASTOMA Moderator: To be Confirmed
14:15 Bevacizumab and glioma: An updateSpeaker: Alba A. Brandes (Italy)
14:35 Second surgery in recurrent glioblastoma: When and why? Speaker: Jörg-Christian Tonn (Germany)
14:55 Recurrent glioblastoma: What are the options in 2015?Speaker: To be Confirmed
15:15 Discussion (15’)
15:30 Coffee Break (30’)
SESSION V: CONTROVERSIES (I) Moderator: To be Confirmed
16:00 Re-irradiation in glioblastomaSpeaker in Favour: Stephanie Combs (Germany)
16:15 Re-irradiation in glioblastomaSpeaker Against: Michael Brada (United Kingdom)
16:30 Discussion (20’)
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SESSION VI: NOVEL CLINICAL DEVELOPMENTSModerator: To be Confirmed
16:50 Taking molecular characterisation to clinical trials Speaker: Wolfgang Wick (Germany)
17:10 Antibody drug conjugates in glioblastoma?Speaker: David Reardon (United States)
17:30 Developments in immunotherapy Speaker: John Sampson (United States)
17:50 Discussion (15’)
DETAILED ADVANCE PROGRAMME: SATURDAY 28 MARCH 2015
08:30 WELCOME TO DAY 2
SESSION VII: CNS METASTATIC DISEASE Moderator: To be Confirmed
08:35 Key aspects of brain metastasis biology that generate new therapeutic opportunitiesSpeaker: Manuel Valiente-Cortes (United States)
09:00 Management of leptomeningeal disease: When and how to treat? Speaker: To be Confirmed
09:25 Targeted therapy for brain metastases?Speaker: Matthias Preusser (Austria)
09:50 Discussion (10’)
SESSION VIII: CONTROVERSIES (II)Moderator: To be Confirmed
10:00 Is surgical cavity irradiation necessary for resected brain metastases? Speaker in Favour: To be Confirmed
10:15 Is surgical cavity irradiation necessary for resected brain metastases? Speaker Against: Riccardo Soffietti (Italy)
10:30 Discussion (10’)
10:40 Coffee Break (20’)
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SESSION IX: RARE TUMOURS: EPENDYMOMAModerator: To be Confirmed
11:00 Surgical managementSpeaker: Manfred Westphal (Germany)
11:25 Non-surgical strategies for ependymomaSpeaker: Roberta Rudà (Italy)
11:50 Discussion (10’)
SESSION X: PRACTICAL NEURO-ONCOLOGYModerator: To be Confirmed
12:00 The management of seizuresSpeaker: Charles Vecht (France)
12:25 Rehabilitation programs for brain tumours patientsSpeaker: Robin Grant (United Kingdom)
12:50 Discussion (10’)
13:00 Closing remarks
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CALL FOR ABSTRACTS
Abstract Submission Opens 12 December 2014
Abstract Submission Closes 12 February 2015
Abstracts can only be submitted online. A link to submit your abstract will be published online when abstract submission opens.
For questions regarding the online submission process, contact: [email protected]
Only abstracts submitted online can be accepted. Abstracts submitted on paper or by e-mail attachment will not be considered.
ABSTRACT POLICIES AND REGULATIONS
With the submission of an abstract to the EORTC-EANO-ESMO 2015 Conference, the first (presenting) author:
n Certifies to be an investigator with a substantial involvement in the clinical study presented in the abstract.
n Accepts responsibility for the accuracy of the submitted abstract (please proofread the abstract carefully prior to submission).
n Accepts the rule that a first (presenting) author can be the first (presenting) author of only one abstract.
n Accepts to be the contact person for all correspondence about the abstract and inform co-authors about its status.
n Confirms that all co-authors are aware of and agree to the content of the abstract and support the data presented.
n Warrants that the data and conclusions presented in the abstract have not been presented or published in the same format and with the same title prior to the date of the EORTC-EANO-ESMO 2015 Conference.
n States that for studies involving human or animal subjects, permission has been obtained from the relevant regulatory authority and properly informed consent given where appropriate.
n Agrees that abstracts submitted to EORTC-EANO-ESMO 2015 Conference are considered both confidential and embargoed from the time of submission. Abstracts presented at EORTC-EANO-ESMO 2015 Conference are embargoed until the first day of the conference.
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ABSTRACT PREPARATION AND SUBMISSION
n The title of the abstract should be brief and objectively describe the study. Do not use capital letters in the title except for words that are always capitalised and do not use non-standard abbreviations. Commercial names may not be used in the abstract’s title (generic names only).
n No more than 10 authors can be listed with institutional affiliations, cities and countries. Mailing addresses and academic degrees should not be mentioned in the author’s list. For co-operative study groups, you may give the name of the group instead of individual institutional affiliations or include the name of the group in the title of the abstract.
n Abstracts should be structured in such a way as to include the following 4 sections:
BackgroundAn introductory sentence indicating the purpose of the study.
Material and methodsA brief description of pertinent experimental procedures.
ResultsA summary of the results of the research.
ConclusionsA statement of the main conclusions.
n Submitted abstracts must not exceed 2500 characters (body of the abstract, including spaces and table).
n Only one data table is permitted in the body of the abstract. Illustration and figures are not allowed and will be deleted if submitted.
n Abbreviations may be used if standard or if spelled out and defined at the first use (put in parentheses immediately after the first mention of a term or phrase). Compounds should be mentioned with the generic name, in lower cases. Commercial names are admitted in the text, with an ®, and if in brackets following the generic name, i.e. “generic (Commercial ®)”.
n The abstract must be submitted in good English. The Scientific Committee reserves the right to reject those abstracts, which are presented in poor English, or may request an immediate revision by the presenter.
n Presentation: the final decision on the presentation format will be made by the Scientific Committee.
ABSTRACT SELECTION PROCESS
Abstracts submitted for presentation at the EORTC-EANO-ESMO 2015 Conference will be reviewed by a panel of experts in the field of the subject and will be judged solely on the data submitted.
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REGISTRATION
INDIVIDUAL REGISTRATION
Pre-registration and corresponding payment has to be received by the indicated deadlines.
Registration Fees
Early Rate Registration and payment received by 9 January 2015
Member* 355 EUR
Non-Member 410 EUR
Student ** 220 EUR
Developing Economies*** 205 EUR
Regular Rate Registration and payment received by 24 February 2015
Member* 410 EUR
Non-Member 520 EUR
Student ** 270 EUR
Desk Rate Registration and payment received as of 25 February 2015
Member* 520 EUR
Non-Member 570 EUR
Student ** 270 EUR
All registration fees include local VAT (18%).
All deadlines are at 24:00 CET Brussels Time on the given date
* Member rate applies to individuals who are members of EORTC, EANO or ESMO.
** Confirmation of ‘in training’ status and a letter from the Head of Department is required as well as a copy of a passport/national identity card proving that the registrant is under the age of 30. These documents should be uploaded on the ECCO website during the registration process. For any queries please contact the EORTC-EANO-ESMO Conference Secretariat by email to [email protected]
*** Developing Economies Rate is applied to individuals from low-income and lower-middle-income economies according to the World Bank listing available at: http://data.worldbank.org/about/country-classifications/country-and-lending-groups
Please register online: www.ecco-org.eu/EEE2015
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PaymentFull payment in EUR has to be received by the corresponding deadline.
Payment by credit card (Eurocard/Mastercard, Visa or American Express) is preferred. Please indicate the card holder’s name as shown on the card.
It is also possible to pay by direct transfer to the EORTC-EANO-ESMO 2015 bank account:
IBAN BE31 7330 5437 1055BIC/SWIFT Code KRED BE BBKBC Bank, Chaussée de Wavre 1662, B 1160 Brussels.Payment by direct bank transfer is not accepted after 24 February 2015.
Please indicate clearly the name of the participant(s), the registration number and the meeting ‘EORTC-EANO-ESMO 2015” in all your remittances.
Registrations on-site can only be paid by credit card (Eurocard/Mastercard, Visa or American Express) or in cash (EUR only).
Confirmation of Individual RegistrationA personalised confirmation email will be sent to each participant once payment of the registration fee has been received in the Conference’s bank account.
Approximately two weeks before the start of the Conference, each confirmed participant will receive an additional email containing important logistical information about the Conference.
Replacements/CancellationsReplacements of confirmed registrations are subject to an administrative fee of 35 EUR per participant. Cancellations of confirmed registrations will be subject to a charge of 75 EUR cancellation fee per participant provided the cancellation is received in writing by 24 February 2015. Refunds by credit card or bank transfer will be made after the Conference.
For cancellations received after 24 February 2015, no refunds will be made.
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GROUP REGISTRATION
Companies and agencies that would like to sponsor the registration fees of a group of participants should contact Emilie Fillod by e-mail: [email protected] or Tel.: +32 (0)2 775 02 47.
Important notice: Please do not register group participants individually online – if you do so, your participants will not be considered as part of a group.
Group Registrations will benefit from early rates when the payment is received by 9 January 2015, even if the list of participant names and professional details has not been finalised by this date.
To facilitate easy processing, please clearly indicate the name of the sponsoring company/travel agency and add the group registration number on the transfer document.
Full names and professional details of participants (including e-mail addresses) for group registrations have to be sent to the EORTC-EANO-ESMO 2015 Conference Secretariat by 24 February 2015 at the latest. For participant names submitted after this deadline, the desk rate will apply.
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FELLOWSHIP GRANTSThe Organising Committee will award a total of 10 Fellowship Grants to young doctors, basic scientists, nurses and other healthcare professionals involved in the neuro-oncology field to attend the EORTC-EANO-ESMO 2015 Conference.
APPLICATION CRITERIA
To be considered for a Fellowship Grant, applicants must:
n Submit a CV;
n Be under the age of 35;
n Provide a letter of recommendation from the Head of the Department/Organisation stating that the applicant is not the recipient of any other financial support.
Deadline for receipt of applications: 12 February 2015
Applications with the subject title ‘EORTC-EANO-ESMO Fellowships’ must be sent by e-mail to: [email protected]
Each Fellowship Grant will cover the cost for registration, free accommodation for a maximum of 2 nights and travel costs up to a maximum of 500 EUR (APEX economy ticket – reimbursed after the Conference).
The EORTC-EANO-ESMO Scientific Committee will review applications and notify Fellowship Grant recipients by the end of February 2015.
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GENERAL INFORMATION
ACCOMMODATION
For the EORTC-EANO-ESMO 2015 Conference, ECCO – the European CanCer Organisation has made an agreement with the Hilton Istanbul Bosphorus Hotel and Convention Centre in Istanbul.
We encourage you to book your accommodation in Istanbul through our local partner, K2 Conference and Event Management Co.
You can check the list of available hotels and book directly online: www.eee2015hotels.org
ACCREDITATION FOR CONTINUOUS MEDICAL EDUCATION (CME)
An application for accreditation has been submitted to the European Accreditation Council for CME (EACCME) of the European Union of Medical Specialists (UEMS). The Accreditation Council of Oncology in Europe (ACOE), in partnership with the UEMS-EACCME, will review and evaluate the event on the basis of the UEMS-EACCME quality criteria (www.uems.net/index.php?id=70).
CURRENCY
Turkey’s official currency is the Turkish Lira (TRY)
Coins 5kr, 10kr, 25kr, 50kr, 1
Banknotes 5, 10, 20 50 100 200
Exchange rate on 8 October 2014 (indication only) 1 EUR = 2.89 TRY
EXHIBITION
The EORTC-EANO-ESMO 2015 Exhibition represents an essential and integral element of the Conference, providing participants with an excellent platform for networking as well as a perfect opportunity to reflect the current evolution in neuro-oncology and the impact of new discoveries at the clinical level that will advance the management, treatment and care of patients with central nervous system tumours.
For information about sponsorship and exhibition opportunities, please contact Bruno De Man by e-mail: [email protected] or Tel.: +32 (0)2 775 02 04
To consider the wide range of opportunities including educational grants, sponsorship items, exhibition space and to access the respective order forms, we kindly invite you to download the Invitation-to-Industry (ITI) brochure available at: www.ecco-org.eu/EEE2015
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INSURANCE
The organisers do not accept liability for individual medical, travel or personal insurance. Participants are strongly advised to make their own arrangements regarding health and travel insurance.
LANGUAGE AND TRANSLATION
The official language of the Conference will be English. Simultaneous translation will not be provided.
LUNCH AND REFRESHMENTS
Lunch is included as part of the registration fee and will be provided at the Conference Venue on Friday.Complimentary coffee will be served during the programme breaks on Friday and Saturday.
OFFICIAL CARRIER
Save up to 20% on travel with the Star Alliance™ network
The Star Alliance member airlines are pleased to be appointed as the Official Airline Network for the EORTC-EANO-ESMO 2015 Conference.
To obtain the Star Alliance Convention Plus discounts and for booking office information please visit www.staralliance.com/en/business-solutions/conventions-plus and:
n Choose ‘For delegates’
n Under ‘Delegates login’ enter conventions code TK19S15
n Choose one of the participating airlines listed
n Call the respective reservation contact listed and quote the conventions code TK19S15 when booking the ticket
Registered participants travelling to the event can qualify for a discount of up to 20%, depending on fare and class of travel booked.
The lead participating airline for this event is Turkish Airlines.
Discounts are offered on most published business and economy class fares, excluding website/internet fares, senior and youth fares, group fares and Round-the-World fares.
When making your travel plans, please present confirmation of your registration or proof of attendance.
PASSPORT AND VISA
A valid passport and/or identity card is required for entry into Istanbul, Turkey. A visa may be required for some countries. For specific information, please contact your local Turkish Embassy at least 3 months prior to your departure to join us in Istanbul.
You can also apply for your entry visa (if applicable) via https://www.evisa.gov.tr/en/
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NOTES
18th ECCO - 40th ESMO
European Cancer CongressReinforcing multidisciplinarity
VIENNA, AUSTRIA, 25 - 29 SEPTEMBER 2015
18
SIOPSIOP Europethe European Society for Paediatric Oncology35
The largest multidisciplinary platform for presenting groundbreaking data to a global audience.
www.europeancancercongress.org
REGISTER NOW
ECC15 148x210 adv 0,1.indd 1 07/10/14 11:25
www.ecco-org.eu/EEE2015
Conference 2015
Trends in Central Nervous System Malignancies
The future of cancer therapy
27 – 28 MARCH 2015 ISTANBUL, TURKEY
Organised by:
Conference SecretariatECCO – the European CanCer OrganisationAvenue E. Mounier 83B-1200 BrusselsBelgiumTel.: +32 (0)2 775 02 01Fax: +32 (0)2 775 02 00Email: [email protected]
supported byTurkish Neuro-Oncology Society
