Hex 2.5

HEAD OFFICE

8th Floor, 123, Gasan digital 2-ro, Geumcheon-gu, Seoul, KoreaTel : 02-2016-7000 Fax : 02-2016-7001 www.osstem.com

TSIII HAImplant SystemCatalog & Manual

* Actual size may be different.M R

TSIII HA Fixture Line Up

Connection

NoMount Fixture Product Code (ex:TS3S4011H)

Pre-mounted Fixture (Simple Mount) Fixture + Mount + Cover Screw : B + Product Code (ex:BTS3S4011H)

Edition 08 / 2014

13

13

Mini Diameter Ø3.5

Regular Diameter Ø4.0

Regular Diameter Ø4.5

Regular Diameter Ø5.0

Connection Mini

Ø3.5

7 -

8.5 TS3M3508H

10 TS3M3510H

11.5 TS3M3511H

13 TS3M3513H

8.5 10 11.5

D

L

DL

Connection Regular

Ø4.0

7 TS3S4007H

8.5 TS3S4008H

10 TS3S4010H

11.5 TS3S4011H

13 TS3S4013H

7 8.5 10 11.5 13

D

L

Connection Regular

Ø4.5

7 TS3S4507H

8.5 TS3S4508H

10 TS3S4510H

11.5 TS3S4511H

13 TS3S4513H

7 8.5 10 11.5 13

D

L

DL

DL

Connection Regular

Ø5.0

6 TS3S5006H

7 TS3S5007H

8.5 TS3S5008H

10 TS3S5010H

11.5 TS3S5011H

13 TS3S5013H

7 8.5 10 11.56

DL

D

L

Ø 3.7

Ø 2.5

Ø 4.2

Ø 2.8

Ø 5.1

Ø 3.7

Ø 4.6

Ø 3.1

Hex 2.1

Hex 2.5

Hex 2.5

Short

02 03TSIII SA Implant System Catalog & Manual TSIII SA Implant

HA : HydroxyApatite coated surfaceOptimal morphology : combination of crater and micro-pit

Optimal surface roughness : Ra 2.8~3.1

Early cell response and bone healing : 40% higher than RBM

Early bone healing : 40% higher than RBM

Early loading possible after 4 weeks of implantation SEM Image and Optical Surface Profile

OSSTEM HA Surface

Surface Layer Properties

Early Cell Response

HA Surface

Pre-clinical Study

OSSTEM HA surface OSSTEM HA surface

XRD Pattern

Inte

nsit

y

15 20 25 30 35 40 2θ

Har

dnes

s (G

Pa)

Conventional HA OSSTEM HA

RBM

2 weeks

*p< 0.05, RBM vs. OSSTEM HA or ‘Z’ Co.HA

40% improvment on boneregeneration on micro pigcompared to RBM and similar orequivalent to competing ‘Z’company’s HA surface implants.

BIC(Bone-to-Implant contact),

12 micro pigs, mandible, n+8

*p< 0.05, RBM vs. SA or HA; p< 0.05, SA vs. HA

Above 98% crystalization degree at HA coated layer

30% hardness improvement with HA coating

4 weeks

HA ‘Z’Co. HA* Improvement of ALP Activity by 24 and Alizarin Red-S assay(Mineralization) by 210% compared to RBM surface

ALP activity on the HA Mineralization on the HACell proliferation on the HA

5

4

3

2

1

0

Culture Plate

HA

250

200

150

100

50

0

w/o dif. w/ dif.

ALP

Act

ivit

y, [p

NP

, [nM

]/10

0ug

Pro

tein

]

Day 7 Day 14 Day 21

HARBM

Mineralization on the HA

Early Cell Response

3000

2500

2000

1500

1000

500

0

HA

100

80

60

40

20

0

RBM HA 'Z'co. HA

BIC

(%)

2 weeks 4 weeks

300

250

200

150

100

50

0

RBM SA HA

Rem

oval

torq

ue (N

cm)

4 weeks 8 weeks 12 weeks

* **

** * *

* *

3000

2500

2000

1500

1000

500

0

HA