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Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells Nilay Sethi, Xudong Dai, Christopher G. Winter, Yibin Kang Cancer Cell Volume 19, Issue 2, Pages 192-205 (February 2011) DOI: 10.1016/j.ccr.2010.12.022 Copyright © 2011 Elsevier Inc. Terms and Conditions

Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells Nilay Sethi, Xudong Dai, Christopher

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Page 1: Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells Nilay Sethi, Xudong Dai, Christopher

Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells 

Nilay Sethi, Xudong Dai, Christopher G. Winter, Yibin Kang 

Cancer Cell Volume 19, Issue 2, Pages 192-205 (February 2011)

DOI: 10.1016/j.ccr.2010.12.022

Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 2: Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells Nilay Sethi, Xudong Dai, Christopher

Figure 1

Cancer Cell 2011 19, 192-205DOI: (10.1016/j.ccr.2010.12.022) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 3: Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells Nilay Sethi, Xudong Dai, Christopher

Figure 2

Cancer Cell 2011 19, 192-205DOI: (10.1016/j.ccr.2010.12.022) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 4: Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells Nilay Sethi, Xudong Dai, Christopher

Figure 3

Cancer Cell 2011 19, 192-205DOI: (10.1016/j.ccr.2010.12.022) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 5: Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells Nilay Sethi, Xudong Dai, Christopher

Figure 4

Cancer Cell 2011 19, 192-205DOI: (10.1016/j.ccr.2010.12.022) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 6: Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells Nilay Sethi, Xudong Dai, Christopher

Figure 5

Cancer Cell 2011 19, 192-205DOI: (10.1016/j.ccr.2010.12.022) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 7: Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells Nilay Sethi, Xudong Dai, Christopher

Figure 6

Cancer Cell 2011 19, 192-205DOI: (10.1016/j.ccr.2010.12.022) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 8: Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells Nilay Sethi, Xudong Dai, Christopher

Figure 7

Cancer Cell 2011 19, 192-205DOI: (10.1016/j.ccr.2010.12.022) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 9: Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells Nilay Sethi, Xudong Dai, Christopher

Figure 8

Cancer Cell 2011 19, 192-205DOI: (10.1016/j.ccr.2010.12.022) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 10: Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells Nilay Sethi, Xudong Dai, Christopher

Cancer Cell 2011 19, 192-205DOI: (10.1016/j.ccr.2010.12.022) Copyright © 2011 Elsevier Inc. Terms and Conditions