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18-04-16
1
Preliminary Update of the KDOQI Vascular Access Guidelines 2018
Charmaine Lok, MD Professor of Medicine, University of Toronto UCSF Vascular Symposium 2018 April 19, 2018 San Francisco
So What’s New: The Outline
• The Process o Building blocks and development over time o Timelines
• Who’s involved • Where we’re at and next steps • What it looks like
• The Statements • The Concepts
The Process
Older Guidelines
Great necessary foundation
Timelines
Scope of Work
Literature review
Data Retrieval & Analysis
Interpretation & Clinical relevance
Quality of Evidence
Strength of Recommendation
Review & Synthesis
Internal Review
External Review
Implementation
Evidence Review Team (ERT)
KDOQI Workgroup
ERT Data ERT has high standards!
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KDOQI “Statement”
4 Kinds: “KDOQI recommends” “KDOQI suggests” “There is inadequate evidence…” “In the opinion of the KDOQI Workgroup…”
Based on ERT extracted data, meeting their
search, extraction and
analysis criteria
Data available in the literature but did not meet ERT criteria, retrieved by workgroup and extensively discussed
ESRD
OUR PATIENTS
Photos taken with consent, permission to share given
New Concepts
Recommendation for Vascular Access for Hemodialysis – Looks the Same??
HD
ESKD Life-Plan
Remember: CKD is a continuum
Stages: I II III IV V RRT
Modality (HD/PD/
Transplant)
RRT Modality
(HD/PD/Transplant)
RRT Modality
(HD/PD/Transplant)
ESKD is part of the CKD continuum
Within ESKD, a patient is anticipated to have a continuum of therapies to help
optimize their life - their ESKD Life-Plan
PD Transplant HD
Our Approach • Focus on a “Life-Plan” for a Patient’s
Dialysis Access Needs
PD 1 Transplant 2 HD: Fistula 3
Nocturnal Home
HD: Graft 4
Example only:
New Philosophy
RIGHTACCESSRIGHTPATIENTRIGHTTIME
RIGHTREASONS
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How?.....P-L-A-N
• Patient
• Life-Plan
• Access • Needs
? ? • Patient
• Life-Plan
• Access • Needs
How?.....P-L-A-N
• Patient
• Life-Plan
• Access • Needs
Patient First
What is the Patient’s ESKD Life-Plan?
How?.....P-L-A-N
• Access • Needs
What is the Patient’s Access Creation Plan
What access, where, when, by whom?
How?.....P-L-A-N
• Access • Needs
What are the remedial measures when the access becomes problematic?
What is the Patient’s Access Contingency Plan
How?.....P-L-A-N
• Access • Needs
What access is next when the current one fails?
What is the Patient’s Access Succession Plan
How?.....P-L-A-N
ü Patient
ü Life-Plan
ü Access ü Needs
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Allied Health
Epidemiology & Statistics
Workgroup Members • Nephrology
o Michael Allon o Timmy Lee o Charmaine Lok o Louise Moist
Workgroup
Nephrology
Surgery Interventional
• Surgery o Marc Glickman o Thomas Huber o Suren Shenoy
• Interventional o Ken Abreo o Arif Asif o Dheeraj Rajan o Tushar Vaccharajani o Alex Yevzlin
• Allied Health & Epi o Brad Astor o Janet Graham o Cindy Roberts
• Pediatric Nephrology o Rudy Valentini
Evidence Review Team
• Timothy J. Wilt, MD, MPH • Nancy Greer, PhD • Michelle Brasure, PhD, MSPH • Areef Ishani, MD, M.C.R. • Yelena Slinin, MD, M.Sc. Minnesota Evidence Review Team: Minneapolis VA Health Care System University of Minnesota Schools of Medicine University of Minnesota School of Public Health
THANK YOU FOR YOUR ATTENTION