Upload
mpiskel
View
3.870
Download
0
Embed Size (px)
Citation preview
What is What is genetics?genetics?
HEREDITYHEREDITYThe study of...The study of...
What is HEREDITY?
The passing of traits from parent The passing of traits from parent to offspring. to offspring.
Why do we care about genetics?
• Genetics has determined the history and will determine the
future of all living things.
• We are in the “Age of Genetics”
Chromosomes, Genes, Traits and Alleles
Chromosomes are strands Chromosomes are strands ofof
______that carry our ______that carry our
__________ __________ __________ __________
Chromosomes• Chromosomes are
made up of many GENES.
• Genes are
instructions for
the TRAITS
you have.
VISUALIZE the GENESEACH X is a EACH X is a chromosome.chromosome.
On the X are little On the X are little marks. Each marks. Each
mark is a gene.mark is a gene.
Where are they? Where are they? IN THE NUCLEUSIN THE NUCLEUS
TEST YOURSELF
1. DNA is held in what part of the cell?1. DNA is held in what part of the cell?
2. DNA is grouped into sets of what in each cell?2. DNA is grouped into sets of what in each cell?
FACT: These 23 sets of chromosomes are called your FACT: These 23 sets of chromosomes are called your genome!genome!
3. Each chromosome contains DNA grouped into something called 3. Each chromosome contains DNA grouped into something called _________ which carries information that tells the cell to make _________ which carries information that tells the cell to make a unique protein that will perform a special function.a unique protein that will perform a special function.
• Genes are instructions for the ___________ you have. Genes are instructions for the ___________ you have.
In your note packet, write down examples of some human traits.
• Example: Eye color is a human trait
Homologous chromosomes, alleles and more
Remember what homologous chromosomes are?
THEY ARE: THEY ARE: A pair of chromosomes containing the same gene sequences, each derived from one parent. The chromosomes
tend to pair during meiosis.
Homologous Chromosomes
Each homologous chromosome has the same traits on it, but they can be for different alleles.
• WHAT IN THE WORLD IS AN ALLELE?
ALLELE
•Possible options for one traitPossible options for one trait
EXAMPLE: brown eye color or blue eye colorEXAMPLE: brown eye color or blue eye color
Using the list of human traits you have already made in your notes, list possible alleles for the traits.
• Example: The trait is eye color– Possible alleles are brown and blue
The homologous chromosomes below have the same traits on them, but they are for two
different alleles.
Both chromosomes in the homologous pair containthe trait for hair texture, but one carries the allele for curly hair & the other one carries the allele for
straight hair.
GENE INTERACTION….
• What the organism looks like.
• The actual genes (alleles) the organism has.
•We use big andsmall letters to symbolize genes
When figuring out what the PHENOTYPE will be when a
certain GENOTYPE is present, you need to find out the
_____________ of each allele.
How do alleles interact with each
other?
3 Gene Interactions
• Dominant vs. Recessive
• Incomplete Dominance
• Codominance
Dominant vs. Recessive
Dominant/Recessive interactions
• The dominant allele will “cover up” the recessive allele.
Incomplete Dominance interactions
When the 2 different alleles are present, the phenotype will look like a BLENDING of the two.
INCOMPLETE DOMINANCE
A trick to remember this is “A trick to remember this is “ININ” ” your “your “blenderblender” we make a shake.” we make a shake.
‘‘IN’COMPLETE=‘BLENDING’IN’COMPLETE=‘BLENDING’
Codominance• Both alleles act as dominant, so
you will get a result with both alleles shown fully.
CODOMINANCE REMEMBERED:
CO- BOTHCO- BOTH
Think of Co-ed (means BOTH boys and girls)Think of Co-ed (means BOTH boys and girls)
Codominance means BOTH traits showCodominance means BOTH traits show
Gene interaction questions(These genes are not actually real, they are for example only)
• A girl inherits a long eyelash gene from her father and a short eyelash gene from her mother. The short eyelash gene is dominant and the long eyelash gene is recessive.
What is the length of the girl’s eyelashes?
Her eyelashes are short
Gene interaction questions(These genes are not actually real, they are for example only)
• The interaction of genes for height of the Scar Barked Fast Sapping Evergreen Tree show incomplete dominance.
A tall tree is crossed with a short tree, what will the height of the new tree be?
Medium height
Gene interaction questions(These genes are not actually real, they are for example only)
• The interaction of genes for height of the Scar Barked Fast Sapping Evergreen Tree show incomplete dominance.
Another question, a short tree is crossed with another short tree, what will the height of the new tree be?
Short height
Gene interaction questions(These genes are not actually real, they are for example only)
• The genes for fur design of Patagonia Panthers are codominant. The 2 possible designs for fur are spotted and striped.
A spotted panther is mated with a striped panther. What will the fur design of the baby panther be?
Spotted with stripes
Heredity and Genotype
http://www.frogstar.com/wav/displaywav.asp?fil=shirley.wav
Look at these cells• Which is haploid? • Which is diploid?• Which is a body cell? Which is a sperm or egg cell?
In each of your body cells, how many genes do you have for 1
specific trait?
2Why?There is one gene on each of the homologous pairs. You got one gene from your mom and one gene from your dad.
Since egg and sperm cells are haploid, how many genes do you have for each trait
in an egg?
In a sperm?
• The egg and sperm both have one gene for each trait.
• The homologous pairs were separated during meiosis.
1111
Remember:Meiosis only occurs in Meiosis only occurs in __________________.__________________.SEX CELLSSEX CELLS
SEXSEX
The homologous pairs were separated during meiosis.
How and when are homologous pairs separated in meiosis in order to make a sperm or an
egg?
Metaphase I: How are the homologous chromosomes lined up?
In metaphase I In metaphase I
of meiosis,of meiosis,
homologous pairs are homologous pairs are
lined up so thelined up so the
homologous pairs homologous pairs
are next are next
to one another.to one another.
Anaphase I: How are homologous
chromosomes separated?Homologous Homologous
pairs are pairs are separated in separated in Anaphase I Anaphase I of meiosis.of meiosis.
At the end of meiosis I, the homologous chromosomes have been separated, the cells are now
haploid.
The homologous pairs are split up randomly, so we don’t know which particular chromosome of each pair will be
found in each cell.
Law of Independent Assortment
http://www.frogstar.com/wav/displaywav.asp?fil=bb-alive.wav
The alleles for a trait separate when gametes are formed. These allele pairs are then randomly united at fertilization.
Review Quiz…
Where did you get each of your chromosomes?
• Half from your mother
• Half from your father
How many genes for each trait do you have in each BODY cell?
•2 genes
How many genes for each trait do you have in each SPERM cell?
1 Gene for each traitWHY?
Sperm are haploid
How many genes for each trait do you have in an EGG cell?
1 Gene for each traitBecause eggs are haploid
When a sperm fertilizes an egg, how many genes for each trait
will the baby have?
It has two genes for each trait. The baby will be diploid
Karyotype: All of an organism’s chromosomes are lined up with homologous
pairs being placed next to one another.
Chromosomes Chromosomes #23 are sex cells.#23 are sex cells.
A Bit ‘O’ Genetic History...
THE STUDY OF GENETICS
The Father of Genetics
Gregor Mendel and His Peas
Mendel and His PeasHe used pea plants because:He used pea plants because:
1)1) Unlike animals, they could not Unlike animals, they could not movemove
2)2) Easier to test MANY plants Easier to test MANY plants whereas animals sometimes whereas animals sometimes
take up more space and take up more space and require more maintenancerequire more maintenance
What else….What else….
Why did he use pea Why did he use pea plants and not plants and not
animals? Discuss…animals? Discuss…
What are 5 traits he was looking at and what were the 2 possible alleles for each?
When the gene interaction is dominant vs. recessive, you need
to know the genotypes of the parents in order to accurately
figure out what the possibilities are for their children.
Remember….
• PHENOTYPE = What the organism looks like.
• GENOTYPE = The genes (alleles) the organism has.
Example: A species of bird has 2 possible alleles for wing color, red and green.
The alleles have a dominant vs. recessive interaction with one another.
The red allele is dominant over the green allele.
We will be representing the red allele as “R” and thegreen allele as “r”.
Red allele (R) is dominant over Green allele (r)• A bird has a red wing, what are the possible
genotypes for red wing?
The bird could have the genoytpe “R R”or “Rr”
• In genetics, there is a special term to describe both of these combinations.
If the 2 alleles are the same (RR) or (rr) they aresaid to be homozygous. “Homo” means “same”
If the 2 alleles are different (Rr) they are called heterozygous. “Hetero” means “different”
• Lemurs have 2 possible alleles for tail appearance, fluffy and straight.
• Fluffy (F) is dominant over straight (f).
The phenotype of lemur #1 is fluffy tailThe phenotype of lemur #2 is straight tail
• What are the possible genotypes for lemur #1?• What are the possible genotypes for lemur #2?
Lemur #1: FF (homozygous) or Ff (heterozygous)Lemur #2: ff (homozygous)
Quiz yourself
A man inherited from his mother, a chromosome which has the blue eye color allele on it. He also inherited from his father, the chromosome which has
the brown eye color allele on it.
• The man has a child, which eye color allele will the child inherit, blue or brown?
Answer: It is impossible to tell, it could be eitherthe Brown or the blue.
What is his genotype? Bb - heterozygous
Did you get Did you get those? those?
You are smart!You are smart!
Predicting possible outcomes
• Punnet squares– Possibilities for
genetic combinations
Punnet square problem #1A man who is heterozygous for brown eyes has a baby with a woman who is heterozygous for brown eyes.
What are the possible phenotypes and genotypestheir children could have? Do a Punnet square
The brown eye allele is dominant over blue.
1. Brown is dominant over blue2. Both parent’s phenotypes are brown.3. Both parents are heterozygous - Bb
Punnet SquareMother’s and father’s genotypes are both BbPossible egg genes are B or bPossible sperm genes are B or b
B b
B bPossible genotypes for offspringare:
BB
Bb
Bb
bb
BB, Bb, bbPossible phenotypes are:Brown and blueWhat are the chances of Getting a brown eyed child? A blue eyed child?The ratio is 3:1 brown to blue. 75% chance of brown and 25% chance of blue
Punnet SquareMother’s and father’s genotypes are both BbPossible egg genes are B or bPossible sperm genes are B or b
B
b
B bPossible genotypes for offspringare:
BB
Bb
Bb
bb
BB, Bb, bbPossible phenotypes are:Brown and blueWhat are the genotypic ratios?
The ratio is 1:2:11 BB 2 Bb 1 bb
brown and yellow 2:2 --> 1:1
Punnet Square Question #2A female duck with yellow feet mates with a maleduck who is heterozygous for brown feet. What are the possible feet colors for the chicks?Brown is dominant over yellow.Mother duck’s genotype is: bb
Father duck’s genotype is: Bb
b
b
B b
Bb bb
Bb bb
Possible phenotypes are:
Possible genotypes are:Bb and bb 2:2 --> 1:1
Going further….
Do some Do some examples in examples in
the class notesthe class notes
Punnet Squares With 2 Traits
Mother’s genotype:Bbll
Father’s genotype:bbLl
A woman who is heterozygous for brown eyes and has small toes marries a man who has blueeyes and heterozygous for large toes. What are the possible genotypes and phenotypes oftheir children?
Brown eyes are dominant over blueLarge toes are dominant over small toes
To form the possible egg and sperm…
Think:Think:
First with third, first with fourthFirst with third, first with fourth
Second with third, second with fourthSecond with third, second with fourthBbll
BlBl BlBl blbl blbl
Punnet Squares With 2 TraitsMother’s genotype: B b l l Father’s genotype: b b L l
Possible eggs: Bl, Bl, bl, bl
Possible sperm:bL, bl, bL, bl
Bl
Bl
bl
bl
bL bl bL bl
BbLl BbLlBbll Bbll
BbLl BbLlBbll Bbll
bbLl bbLlbbll bbll
bbLl bbLlbbll bbll
Punnet Squares With 2 TraitsMother’s genotype: B b l l Father’s genotype: b b L l
Bl
Bl
bl
bl
bL bl bL bl
BbLl BbLlBbll Bbll
BbLl BbLlBbll Bbll
bbLl bbLlbbll bbll
bbLl bbLlbbll bbll
Possible genotypes:BbLl BbllbbLl bbll1:1:1:1 Ratio
Possible phenotypes:
Brown eyes/large toes
Brown eyes/small toes
blue eyes/large toes
blue eyes/small toes
1:1:1:1 Ratio
Punnet Squares 2 Traits - DifficultA female wavy fur spaniel with heterozygous brown
paws is mated with a male wavy fur spaniel with heterozygous brown paws.
•What are the possible genotypes and ratios? •What are the possible phenotypes and ratios?
Straight and curly fur show incomplete dominance.Brown paws are dominant over white paws.
Female’s genotype is:Male’s genotype is: csBb
csBb
Punnet Squares 2 Traits - DifficultFemale’s genotype is: csBb Male’s genotype is: csBb
Possible genes in eggs: cB, cb, sB, sbPossible genes in sperm: cB, cb, sB, sb
cB
cb
sB
sb
cB cb sB sb
ccBB ccBb csBB csBb
ccBb ccbb csBb csbb
csBB csBb ssBB ssBb
csBb csbb ssBb ssbb
Punnet Squares 2 Traits, #2Genotypes:
cB
cb
sB
sb
cB cb sB sb
ccBb csBB csBb
ccBb ccbb csBb csbb
csBB csBb ssBB ssBb
csBb csbb ssBb ssbb
ccBB ccBb csBB csBb ccbbcsbb ssBB ssBb ssbb
csBB 2csBb 4ccbb 1csbb 2ssBB 1ssBb 2ssbb 1
ccBB 1ccBb 2
Genotype ratio:
ccBB
1:2:2:4:1:2:1:2:1
Punnet Squares 2 Traits, #2Genotypes: CCBB CCBb CSBB CSBb CCbb
CSbb SSBB SSBb SSbb
CSBB 2CSBb 4CCbb 1CSbb 2SSBB 1SSBb 2SSbb 1
CCBB 1CCBb 2
Genotype ratio: Phenotype ratio:Curly/Brown 3Wavy/Brown 6Curly/white 1Wavy/white 2Straight/Brown 3Straight/white 1
3 : 6 : 1 : 2 : 3 : 1
Sometimes genes change by accident.
It is call a…
MutationsOOPS!OOPS!
There are 3 possible outcomes
when a mutation occurs...
1. LethalIt kills the organism before birth or later.
2. Negative Effect
Ranging from minor severe None at all
3. Positive Effect Very rarely happens this way
Makes organism better adapted
2 examples are…
• A mutation occurred, and actually helped these organism survive!
•Advantage increases an animal's chances of survival.
•Chances of reproducing and passing on the trait.
Example #1: Camouflage
•Mutation that happened in malaria-prone regions.
•More likely to survive malaria epidemics.
•They survived when others did not, this allowed the trait to be passed down through generations.
Example #2: Sickle Cell Anemia
Types of Mutations
Type A:Mutations that occur during
Meiosis
Type B:Mutations that occur during
DNA replication
Type A:Mutations That Occur
During Meiosis
Mutations That Occur During Meiosis
Examples:Examples:
Duplication MutationDuplication Mutation
Deletion MutationDeletion Mutation
Inversion MutationInversion Mutation
TranslocationTranslocation
NondisjunctionNondisjunction
Type A:Mutations That Occur During Meiosis
During Prophase Crossing over done incorrectly
Type A:Mutations That Occur During Meiosis
During Anaphase II Chromatids separating incorrectly
2424 23
4747
Type B:POINT MUTATIONS
Mutations that occur during
DNA replication.
Mutations that arise from nucleotide
bases having errors are called
POINT MUTATIONSPOINT MUTATIONS
POINT MUTATIONS ARE
Base Pair AdditionBase Pair Addition
Base Pair DeletionBase Pair Deletion
Base Pair SubstitutionBase Pair Substitution
Let’s see if you can figure it out!Activity
Fill in your pages
What causes mutations?
MUTATION CAUSES1.1. Natural Causes- mistakes in the DNANatural Causes- mistakes in the DNA
•IN THE IN THE CLEANING SUPPLIESCLEANING SUPPLIES YOU USE YOU USE
•IN THE IN THE TOBACCOTOBACCO THAT PEOPLE USE THAT PEOPLE USE
2. Environmental Factors…Mutagens2. Environmental Factors…Mutagens
•IN THE IN THE FOOD FOOD YOU YOU EATEAT
3. UV-Rays & X-Rays3. UV-Rays & X-Rays
How many people do you know who smoke?
1 out of every 3 tobacco users will die from a tobacco
related illness.
Think for a second and count them.
TobaccoTobaccoStinksSucksSmellsAnd KILLS
In the dentist’s office, why do they place a lead apron over a person’s lap?
They want to protect the reproductive organs. If a mutation occurs in the reproductive organs, it may end up disfiguring a future child, or worse.
4. Heavy Metals
• Lead • Mercury• Cadmium• (Not heavy
metal like Metallica)
MUTATION CAUSES CONT…
5. UV Raysa. Holes in the ozone
layerb. Tanning beds
6. Nuclear radiation
Things that cause mutations are called
Mutagens
Exposure to mutagens can cause mutations in 2
general areas.1. Mutations in the sex cells, eggs and sperm.What do you think these mutations might lead to?
2. Mutations in the other cells of the body. What do you think these might lead to?
BIRTH DEFECTS OR DEATHBIRTH DEFECTS OR DEATH
CANCERCANCER
If you do not mind…
•Please stand up if you or someone in your Please stand up if you or someone in your immediate family has had cancer.immediate family has had cancer.
•Please stand up if someone you are related Please stand up if someone you are related to has had cancer.to has had cancer.
•Please stand up if you know someone Please stand up if you know someone personally who has had cancer.personally who has had cancer.
•Please stand up if you have a friend who is Please stand up if you have a friend who is related to someone who has had cancer.related to someone who has had cancer.
So what exactly is this ugly disease?
Cancer is a disease where cellsCancer is a disease where cellsbegin to divide by mitosis begin to divide by mitosis
uncontrollably.uncontrollably.
A mutation(s) can occur in one single cell, and by the process of mitosis it can grow into tens of thousands or more cells in a relatively short period of time.
What forms when a cell has What forms when a cell has undergone mitosis uncontrollably undergone mitosis uncontrollably
for a while in one central spot?for a while in one central spot?
A Tumor
Cancer Treatments
1. Surgerical removal of cancer1. Surgerical removal of cancer
2. Chemotherapy- Treatment with 2. Chemotherapy- Treatment with drugs that kill cancer cells or make drugs that kill cancer cells or make
them less active.them less active.
3. Radiation- 3. Radiation- uses high-energy uses high-energy waves, such as X-rays (invisible waves, such as X-rays (invisible
waves that can pass through most waves that can pass through most parts of the body), to damage and parts of the body), to damage and
destroy cancer cells.destroy cancer cells.
4. Another option is a STEM CELL 4. Another option is a STEM CELL TRANPLANTTRANPLANT
Radiation and anti-cancer drugs are very good at destroying
cancer cells, but unfortunately they also destroy healthy cells.
http://www.leapingmedia.com/Media/TransplantAnimation.movhttp://www.leapingmedia.com/Media/TransplantAnimation.mov
THE HUMAN SYSTEM
• 44 “regular” chromosomes, called autosomes
• 2 sex chromosomes (23rd Pair)–X–YTHAT MEANS HUMANS HAVE A TOTAL OF ____
CHROMOSOMES!
What can you tell me about this person by looking at their karyotype?
• He is Male
MALES are MALES are XYXY
What can you tell me about this person by looking at their karyotype?
• She is female
Females are Females are XXXX
What about this person?
Nondisjunction. Heis trisomy for the sex
chromosomes.
• Male with Klinefelter Syndrome.
• What kind of mutation caused this?
What about this person?
Nondisjunction. Sheis monosomy for the X sex chromosome.
• Female with Turner Syndrome.
• What kind of mutation caused this?
Sex linked genesThe X and Y chromosomes do not carry the same genes on
them.
• In fact, the Y chromosome does not carry many useful genes at all.
• When deciding what traits a person carries on their sex chromosomes, it is often useful to consider males as if they are actually missing a chromosome because there are very few useful genes located on the Y chromosome. (Sorry Guys)
Sex Linked GenesWhen we refer to a “sex linked gene”, it meansthat the gene is located on a sex chromosome.
Very few traits are found on the Y chromosome, so when we talk about sex linked genes, you can assume the gene is located on the X chromosome.
Sex Linked Punnet SquaresWhen doing Punnet squares with sex linkedgenes, you have to include the sex chromosomeas well as the gene it carries.
To show that an X chromosome carries a gene,you put the letter as a superscript of the X.
XBXb would indicate a female who isheterozygous for the trait “B”
Color blindness is an X linked gene
A woman who is a carrier (heterozygous) of thecolor blind gene has children with a man who isnot colorblind.
Colorblind (c) is a recessive gene to the dominant color seeing gene (C).
What are the chances that they could have a sonwho is colorblind? A daughter who is color blind?
Genotype of the mother is:
Genotype of the father is:
XCXc
XCY
Possible genotype for the egg:
Possible genotype for sperm:
Color blindness is an X linked geneGenotype of the mother is:
Genotype of the father is:
XCXc
XCY
XC or Y
XC
XC
Xc
YXC or Xc
Possible genotype for the egg:Possible genotype for sperm:
Color blindness is an X linked gene
XC or Y
XC
XC
Xc
Y
XC or Xc
XC XC XC Y
YXcXC Xc
The chance that they willhave a colorblind SON is 50%
The chance that they willhave a colorblind DAUGHTER is 0%(but 50% for a carrier)
Color blindness is an X linked geneA woman who is homozygous for color seeing has a childwith a man who is colorblind. What are the chances that his daughter will be colorblind?What are the chances that his son will be colorblind?
Colorblind (c) is a recessive gene to the dominantcolor seeing gene (C).
Woman’s genotype:
Man’s genotype:
XC XC
Xc Y
There is 0% chance thatthey will have a colorblind boy or girl.
But 100% chanceThat their daughterswould all be carriers.
Color blindness is an X linked geneWoman’s genotype:
Man’s genotype:
XC XC
Xc Y
XC
Xc
XC
Y
XC Xc XC Y
YXcXC XC
Color Blindness Test
What number do you see?Okay, so this is the one that everyone is
supposed to be able to see!
Red/Green Color Blindness Test
What number do you see?
7
Red/Green Color Blindness Test
What number do you see?
2
Male patterned baldness is X linked
One of the science teachers above has 2 children,a boy and a girl. His wife is heterozygous for the male patterned baldness gene. What are the possibilities that his son or daughter will have male patterned baldness?(Male patterned baldness is a recessive allele)
Results
XH
Xh
Xh
Y
H = Hair h = bald
XH XH
Xh Xh
Xh
Xh
Y
Y
50% chance son will bald50% chance daughter could baldTestosterone is needed to “turn on” this balding gene,so it is very unlikely that agirl will go bald even if she is homozygous for this balding gene.
If a young man wants to get some idea if he may have male
patterned baldness, who should he look at, his father
or his mother’s father? Why?
Because the male patterned baldness is sex linked, he did not receive the gene from his father, he got it from his mother. Looking at the father’s side of the family is useless because he got his Y chromosome from his
dad, not an X.
PedigreePedigrees are symbolic representations of a familyand the alleles they have.
When creating a pedigree, this symbol means the person is male.
When creating a pedigree, this symbol means the person is female.
When creating a pedigree, this symbol means the person is of unknown gender. This is oftenused if in the history of family, a child died at birth and the gender of the child is not known.
PedigreeThe horizontal line connecting this man and woman means that they are married.
The same symbol as above but having a diagonal line through the marriage linemeans that the couple is divorced.
This collection of symbols means that the man is divorced and remarried.
A symbol with a diagonal line through it means thatThe person is no longer living.
Pedigree
What collection of symbols could show a couple who is married and has son and a daughter.
Pedigree
A couple is married, they haveA son and a daughter. Their son is married and he and his wife have a son.
Get the idea?
PedigreeRepresenting genetic traits within a pedigree.
The symbol colored in means that the person is homozygous for the allele.
The symbol half colored in means that the person is heterozygous for the allele.
The symbol not colored in means that the person does not have the allele.
Pedigree for the blue eye alleleA pedigree for a brown eye allele
The brown eye allele is dominant
In this family,who has brown eyes?
Everyone except This woman.
Quiz Time
YOU
Who is this? Sister
Quiz Time
YOU
Who is this? Maternalgrandfather
Quiz Time
YOU
Who is this? half sister
Quiz Time
YOU
What information do weknow about your grandmother?
She haspassed away
Quiz Time
YOU
Who is this? Aunt
Quiz Time
YOU
Pedigree for the big nose allele, it is recessive.
Who has a big nose?You and your aunt
Quiz Time
YOU
Pedigree for the big nose allele, it is recessive.
What is the genotype ofyour cousin?
Quiz Time
YOU
Pedigree for the big nose allele, it is recessive.
What is the genotype ofyour cousin? Heterozygous
Paternity tests
• It is possible to tell if a certain man is the father of a baby by comparing the baby’s DNA to his and the baby’s mother.
• Since the DNA the baby has came from it’s mother and father, the DNA should all be accounted for between the 2 parents.
Paternity Test - Match the DNA
Paternity Test - Match the DNA
Paternity Test - Match the DNA
DNA fingerprinting• DNA fingerprinting is quite similar to a paternity
test, but the person’s DNA is compared to DNA found at the crime scene. If the chromosome fragments line up, it positively IDs the person as being part of the crime.