UNIVERSITY OF MIAMIUNIVERSITY OF MIAMI . CURRICULUM VITAE . MARY BARTLETT BUNGE, Ph.D. 1. Date: June 8, 2015 . PERSONAL 2. Name: 3. Home Phone: Mary Bartlett Bunge …phydatabase.med.miami.edu/documents/cv/Bartlett... ·

UNIVERSITY OF MIAMI CURRICULUM VITAE

MARY BARTLETT BUNGE, Ph.D.

1. Date: June 8, 2015

PERSONAL

2. Name:

3. Home Phone:

Mary Bartlett Bunge

4. Office Phone: (305) 243-4596

5. Home Address:

6. Current Academic Rank: Professor

7. Primary Department: Department of Cell Biology University of Miami Miller School of Medicine

8. Secondary Appointments: Department of Neurological Surgery, Department of Neurology

9. Citizenship: USA

10. Visa Type: None

HIGHER EDUCATION

11. Institutional:

B.S. Biology, Simmons College 1953

M.S. Medical Physiology: Thesis advisor, R.F. Schilling, M.D., University of Wisconsin Medical School 1955

Ph.D. Zoology-Cytology: Thesis advisor, Dr. Hans Ris, 1960 University of Wisconsin

12. Non-institutional:

Diploma Northfield School for Girls 1949

13. Certification: None

Curriculum Vitae BUNGE, Mary Bartlett, Ph.D. Page -2- EXPERIENCE 14. Academic: 2006 Doctor of Humane Science, honoris causa from Simmons College, Boston, MA 2003-Present Christine E. Lynn Distinguished Professor of Neuroscience 1996-1997 Interim Scientific Director, The Miami Project to Cure Paralysis, University of Miami School of

Medicine, Miami, FL

1991-Present Professor of Cell Biology and Anatomy, Neurological Surgery, and Neurology, The Miami Project to Cure Paralysis, University of Miami School of Medicine, Miami, FL

1989-1991 Professor of Cell Biology and Anatomy and Neurological Surgery, The Miami Project to Cure

Paralysis, University of Miami School of Medicine, Miami, FL 1978-1989 Professor, Department of Anatomy and Neurobiology, Washington University School of

Medicine, St. Louis, MO. 1984 MRC Cell Biophysics Unit, King's College, London; Sabbatical with Dr. Dennis Bray.

(July-Dec) 1974-1978 Associate Professor (with tenure), Department of Anatomy and Neurobiology, Washington

University School of Medicine, St. Louis, MO. 1972-1974 Research Associate Professor, Department of Anatomy and Neurobiology, Washington

University School of Medicine, St. Louis, MO. 1970-1972 Research Assistant Professor, Department of Anatomy and Neurobiology, Washington University

School of Medicine, St. Louis, MO. 1963-1970 Research Associate, Department of Anatomy, Columbia University College of Physicians and

Surgeons. 1968-1969 Research Associate, Department of Neurobiology, Harvard Medical School; Sabbatical with Drs.

E. Furshpan and D. Potter. 1957-1960 Research Assistant, Department of Zoology, University of Wisconsin. 1956-1957 Teaching Assistant (Zoology 1), Department of Zoology, University of Wisconsin. 1953-1956 Research, Project Assistant, Department of Medicine, University of Wisconsin Medical School. 1952 Summer Student (Dr. Philip R. White), College Program at Roscoe B. Jackson Memorial

Laboratory. 15. Non-Academic: None 16. Military: None

Curriculum Vitae BUNGE, Mary Bartlett, Ph.D. Page -3- PUBLICATIONS 17. Books and monographs published:

Kanno H, Pearse DD, Ozawa H, Itoli E, Bunge MB (2015) Schwann cell transplantation for spinal cord injury repair: its significant therapeutic potential and prospectus. Rev Neurosci 26:121-128 Kwon BK, Soril LJ, Bacon M, Beattie MS, Blesch A, Bresnahan JC, Bunge MB, et al. (2013) Demonstrating efficacy in preclinical studies of cellular therapies for spinal cord injury – How much is enough? Exp Neurol 248:30-44. Williams RR, Bunge MB (2012) Schwann cell transplantation: A repair strategy for spinal cord injury? In: Functional Neural Transplantation III. Primary and Stem Cell Transplantation for Brain Repair (SB Dunnett and A Bjorklund, eds) Part 2. Prog Brain Res 201:295-312. Bunge MB, Wood PM (2012) Realizing the maximum potential of Schwann cells to promote recovery from spinal cord injury. Chapter 34 in Handbook of Clinical Neurology, Spinal Cord Injury, 3rd Series (J Verhaagan, JW McDonald, Eds), Vol. 109:523-540, Elsevier, N.Y. Kocsis JD, Bunge MB (2012) Transplantation of Schwann cells and olfactory ensheathing cells as a therapeutic strategy in spinal cord injury. In: Textbook of Neural Repair and Rehabilitation. ME Selzer et al. (Eds) Cambridge Univ. Press, Cambridge. (In press)

Bates ML, Puzis R, Bunge MB (2011) Preparation of spinal cord injured tissue for light and electron microscopy including preparation for immunostaining. Conventional Animal Models of Movement Disorders (EL Lane, SB Dunnett, Eds), Springer Humana, N.Y. Neuromethods 62:381-399.

Fortun J, Hill CE, Bunge MB (2009) Combinatorial strategies with Schwann cell transplantation to improve repair of the injured spinal cord. Neurosci Letters 456 (3):124-132.

Bunge MB (2008) Novel combination strategies to repair the injured mammalian spinal cord. J Spinal Cord Med. (Donald Munro Lecture, American Paraplegia Society, 2007) 31:262-269.

Courtine G, Bunge MB, Fawcett JW, Grossman RG, Kaas JH, Lemon R, Maier I, Martin J, Nudo RJ, Ramon-Cueto A, Rouillier EM, Schnell L, Wannier T, Schwab ME, Edgerton VR, (2007) Can experiments in nonhuman primates expedite the translation of treatments for spinal cord injury in humans? Nat Med 13:561-566.

Pearse DD, Bunge MB (2006) Designing cell-and gene-based regeneration strategies to repair the injured spinal cord. Special issue: Experimental Strategies to Repair the Injured Spinal Cord. M Oudega, B Blits, J Verhaagen, G Boer, (eds), J Neurotrauma 23:437-452. Blits B, Bunge MB (2006) Direct gene therapy for repair of the spinal cord. Special issue:Experimental Strategies to Repair the Injured Spinal Cord. M Oudega, B Blits, J Verhaagen, G Boer (eds), J Neurotrauma 23:508-20.

Bunge MB, Wood PM (2006) Transplantation of Schwann cells and olfactory ensheathing cells to promote

regeneration in the CNS. In:Textbook of Neural Repair and Rehabilitation. ME Selzer, S Clarke, LG Cohen, PW Duncan & FH Gage (eds), Cambridge Univ. Press, Cambridge, pp.513-531.

Moon LDF, Bunge MB (2005) From animal models to humans: Strategies for promoting CNS axon regeneration and recovery of limb function after spinal cord injury. J Neurology Phys Therapy 29:55-69.

Pearse DD, Bunge MB (2004) Cyclic AMP and cell transplantation in paralysis research: promoting nerve fiber protection, growth and myelination to improve functional recovery. Discovery Med 4:199-202.

Curriculum Vitae BUNGE, Mary Bartlett, Ph.D. Page -4-

Bunge MB (2004) Mary Bartlett Bunge, Ph.D. (with partial commentary on Richard P. Bunge, M.D.) In:The History of Neuroscience in Autobiography. LR Squire (ed), vol.4, pp.40-72, Academic Press, NY. Requested chapter. Bunge MB, Pearse DD (2003) Transplantation strategies to promote repair of the injured spinal cord. J Rehab Res Dev 40:55-62 (Supplement 1).

Pearse DD, Pereira FC, Chatzipanteli K, Dietrich WD, Bunge MB (2002) The use of antisense-mediated inhibition to delineate the role of inflammatory agents in the pathophysiology of spinal cord injury, Scientific World Journal, 2:133-135.

Bunge MB (2002) Bridging the transected or contused adult rat spinal cord with Schwann cell and olfactory glia transplants. Progress in Brain Res, Rossignol S, McKerracher L, Doucet G (eds) 137:275-282.

Bunge MB (2001) Bridging areas of injury in the spinal cord. Neuroscientist 7:325-339

Jones LL, Oudega M, Bunge MB, Tuszynski MH (2001) Neurotrophic factors, cellular bridges, and gene therapy for spinal cord injury. J Physiol 533:83-89.

Plant GW, Ramón-Cueto A, Bunge MB (2001) Transplantation of Schwann cells and ensheathing glia to improve regeneration in adult spinal cord. In:Axonal Regeneration in the Central Nervous System. Ingoglia NA, Murray M (eds). Marcel Dekker Inc., New York, pp.529-561.

Kleitman N, Bunge MB (2000) Olfactory ensheathing glia: their application to spinal cord regeneration and remyelination strategies. Topics in Spinal Cord Inj Rehab 6:65-81.

Sagen J, Bunge MB, Kleitman N (2000) Transplantation strategies for treatment of spinal cord dysfunction and injury. In:Principles of Tissue Engineering, 2nd Edition. Lanza RP, Langer R, Vacanti JP (eds). Academic Press, New York, pp.799-819.

Bunge MB (2000) What type of bridges will best promote axonal regeneration across an area of injury in the adult mammalian spinal cord? In:Degeneration and Regeneration in the Nervous System. Saunders NR, Dziegielewska KM (eds). Harwood Academic Publishers, Berkshire, UK, pp.171-189.

McDonald JW and the Research Consortium of the Christopher Reeve Paralysis Foundation (l999) Repairing the damaged spinal cord. Sci Amer 281:64-73.

Bunge MB, Kleitman N (1999) Neurotrophins and neuroprotection improve axonal regeneration into Schwann cell transplants placed in transected adult rat spinal cord. In:CNS Regeneration: Basic Science and Clinical Advances. MH Tuszynski, JH Kordower (eds). Academic Press, New York, pp.631-646.

Bunge MB, Kleitman N (1997) Schwann cells as facilitators of axonal regeneration in CNS fiber tracts. In: Altschul Symposia Series, Volume 4: Cell Biology and Pathology of Myelin: Evolving Biological Concepts and Therapeutic Approaches. BHJ Juurlink, RM Devon, JR Doucette, AJ Nazarali, DJ Schreyer, VMK Verge (eds), Plenum Press, New York, pp.319-333.

Bunge MB (1993) Schwann cell regulation of extracellular matrix biosynthesis and assembly. In:Peripheral Neuropathy (3rd Ed), PJ Dyck, PK Thomas, J Griffin, PA Low, J Poduslo (eds). WB Saunders, Philadelphia, pp.299-316. Watson BD, Holets VR, Prado R, Bunge MB (1993) Laser-driven photochemical induction of spinal cord injury in the rat: Methodology, histopathology, and applications. Neuroprotocols 3:3-15.

Guénard V, Xu XM, Bunge MB (1993) The use of Schwann cell transplantation to foster central nervous system repair. Seminars in the Neurosciences 5:401-411.


Bunge MB, Paino CL, Fernandez-Valle C (1993) Implantation of cultured Schwann cells to foster repair in injured mammalian spinal cord. In:Tissue Engineering: Current Perspectives; E Bell (ed). Boston: Birkhäuser, pp.48-57. Bunge MB, Clark MB, Dean AC, Eldridge CF, Bunge RP (1990) Schwann cell function depends upon axonal signals and basal lamina components. Ann NY Acad Sci 580:281-287. Invited paper. Wood P, Moya F, Eldridge C, Owens G, Ranscht B, Schachner M, Bunge MB, Bunge R (1990) Studies of the initiation of myelination by Schwann cells. Ann NY Acad Sci Invited paper. 605:1-14. Bunge MB, Bunge RP, Kleitman N, Dean AC (1989) Role of peripheral nerve extracellular matrix in Schwann cell function and in neurite regeneration. Developmental Neuroscience, S. Karger AG, Basel, Switzerland, 11:348-360.

Bunge MB, Johnson MI, Ard MD, Kleitman N (1987) Factors influencing the growth of regenerating nerve fibers in culture. In: Progress in Brain Research, FJ Seil, E Herbert, BM Carlson (eds). Elsevier, 71:61-74.

Bunge MB, Bunge RP (1985) Source and function of basal lamina in peripheral nerve. In: Basement Membranes, S Shibata (ed). Elsevier Science Publ., New York, pp.363-371.

Bunge RP, Bunge MB (1984) Tissue culture observations relating to peripheral nerve development, regeneration and disease. In:Peripheral Neuropathy (2nd edition), PJ Dyck, PK Thomas, EH Lambert, RP Bunge (eds). WB Saunders, Philadelphia, Vol. 1, pp.378-399.

Bunge MB, Bunge RP, Carey DJ, Cornbrooks CJ, Eldridge CF, Williams AK, Wood PM (1983) Axonal and nonaxonal influences on Schwann cell development. In:Developing and Regenerating Vertebrate Nervous Systems, PW Coates, RR Markwald, AD Kenny (eds). Alan R. Liss, New York, pp.71-105.

Bunge MB, Johnson MI, Argiro V (1983) Studies of regenerating nerve fibers and growth cones. In:Spinal Cord Reconstruction, CC Kao, RP Bunge, PJ Reier (eds). Raven Press, New York, pp.99-120.

Bunge RP, Bunge MB, Williams AK, Wartels LK (1982) Does the dystrophic mouse nerve lesion result from an extracellular matrix abnormality? In:Disorders of the Motor Unit, D Schotland (ed). John Wiley & Sons, Inc., New York, pp.23-34.

Bunge RP, Bunge MB, Carey DJ, Cornbrooks CJ, Higgins DH, Johnson MI, Iacovitti L, Kleinschmidt DC, Moya F, Wood P (1982) Functional expression in primary nerve tissue cultures maintained in defined medium. Cold Spring Harbor Conference on Cell Proliferation 9:1017-1031.

Bunge RP, Bunge MB (1981) Cues and constraints in Schwann cell development. In: Studies in Developmental Neurobiology, WM Cowan (ed). Oxford University Press, New York, pp.322-353.

Bunge RP, Bunge MB, Okada E, Cornbrooks CJ (1980) Abnormalities expressed in cultures prepared from peripheral nerve tissues of trembler and dystrophic mice. In:Neurological Mutations Affecting Myelination, N Baumann (ed). Elsevier/North-Holland Biomedical Press, INSERM Symp. 14, pp.433-446

Bunge R, Moya F, Bunge MB (1980) Observations on the role of Schwann cell secretion in Schwann cell-axon interactions. In:Neurosecretion and Brain Peptides: Implications for Brain Function and Neurological Disease, JB Martin, S Reichlin, KL Bick (eds). Raven Press, New York, pp.229-242.

Bunge RP, Bunge MB (1975) Tissue culture in the study of peripheral nerve pathology. In:Peripheral Neuropathy, PJ Dyck, PK Thomas, EH Lambert (eds). WB Saunders Co.1, Philadelphia, pp. 391-409.


Bray D, Bunge MB (1973) The growth cone in neurite extension. In:Locomotion of Tissue Cells, CIBA Foundation Symposium 14, Associated Scientific Publishers, New York, pp.195-209.

Copenhaver WM, Bunge RP, Bunge MB (1971) Bailey’s Textbook of Histology. 16th edition. The Williams and Wilkins Company, Baltimore, Maryland. Bunge RP, Bunge MB, Ris H (1962) Electron microscopic observations on normal, demyelinating, and remyelinating white matter. In: Proc. IV International Congress of Neuropathology, Sept. 1 4-8, 1961, Munich, Vol. II, H Jacob (ed). Stuttgart, Germany, George Thieme Verlag, 136-142.

18. Juried or refereed journal articles and exhibitions:

Williams RR, Venkatesh I, Pearse DD, Udvadia A J, Bunge MB (2015) MASH1/Ascl1a leads to GAP43 expression and axon regeneration in the adult CNS.PLOS ONE (in press) Ruschel J, Hellal F, Flynn KC, Dupraz S, Elliot D, Tedeschi A, Bates M, Sliwinski C, Brook G, Dobrint K, Peitz M, Brustle O, Norenberg M, Blesch A, Wiedner N, Bunge MB, Bixby JL, Bradke F.(2015)Systemic administration of epothilone B promotes axon regeneration after spinal cord injury. Science 348:347-52 Williams RR, Henao M, Pearse DD, Bunge MB (2015) Permissive Schwann cell graft/spinal cord interfaces for axon regeneration. Cell Transplantation 24: 115-131. Flight RM, Harrison BJ, Mohammad F, Bunge MB, Moon LD, Petruska JC, Rouchka EC (2014) categoryCompare, an analytical tool based on feature annotations. Front Genet doi: 10.3389/fgene.2014.00098.eCollection.

Lemmon VP, Ferguson AR, Popovich PG, Xu XM, Snow DM, Igarashi M, Beattie CE, Bixby JL. et al.,(2014) Minimum information about a spinal cord injury experiment: A proposed reporting standard for spinal cord injury experiments. J Neurotrauma 31: 1354-13

Kanno H, Pressman Y, Moody A, Berg R, Muir EM, Rogers JH, Ozawa H, Itoi E, Pearse DD, Bunge MB (2014) Combination of engineered Schwann cell grafts to secrete neurotrophin and chondroitinase promotes axonal regeneration and locomotion after spinal cord injury. J Neuroscience 34(5):1838-55.

Enomoto M, Bunge MB, Tsoulfas P (2013) A multifunctional neurotrophin with reduced affinity to p75NTR enhances transplanted Schwann cell survival and axon growth after spinal cord injury. Exp Neurol (In press). Flora G, Joseph G, Patel, S, Singh A, Bleicher D, Barakat DJ, Louro J, Fenton S, Garg M, Bunge MB, Pearse DD (2012) Combining neurotrophin transduced Schwann cells and Rolipram to promote functional recovery from spinal cord injury. Cell Transplantation (In press) Hill CE, Brodak DM, Bunge MB (2012) Dissociated predegenerated peripheral nerve transplants for spinal cord injury repair: a comprehensive assessment of their effects on regeneration and functional recovery compared to Schwann cell transplants. J Neurotrauma 29(12): 2226-43. Gamez Sazo RE, Maenaka K, Gu W, Wood PM, Bunge MB (2012) Fabrication of growth factor- and extracellular matrix-loaded, gelatin-based scaffolds and their biocompatibility with Schwann cells and dorsal root ganglia. Biomaterials 33(33):8529-39. Sparrow N, Manetti ME, Bott M, Fabianac T, Petrilli A, Bates ML, Bunge MB, Lambert S, Fernandez-Valle C (2012) The actin severing protein cofilin is downstream of neuregulin signaling and is essential for Schwann cell myelination. J Neurosci. 32(15):5284-97.

http://www.ncbi.nlm.nih.gov/pubmed?term=Lemmon%20VP%5BAuthor%5D&cauthor=true&cauthor_uid=24870067

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Morton PD, Johnstone JT, Ramos AY, Liebl DJ, Bunge MB, Bethea JR (2012) Nuclear factor-kB activation in Schwann cells regulates regeneration and re-myelination. Glia 60(4):639-50 Williams RR, Pearse DD, Tresco PA, Bunge MB (2012) The assessment of adeno-associated vectors as potential intrinsic treatments for brainstem axon regeneration. J Gene Med. 14(1):20-34. Bunge MB, Pearse DD (2012) Response to the report, “A re-assessment of a combinatorial treatment involving Schwann cell transplants and elevation of cyclic AMP on recovery of motor function following thoracic spinal cord injury in “rats” by Sharp el al. (this volume). Exp Neurol 233(2):645-8. Hurtado A, Marcillo A, Frydel B, Bunge MB, Bramlett HM, Dietrich WD (2012) Anti-CD11d monoclonal antibody treatment for rat spinal cord compression injury. Exp Neurol 233(2):606-11. Hill CE, Guller Y, Raffa SJ, Hurtado A, Bunge MB (2010) A calpain inhibitor enhances the survival of Schwann cells in vitro and after transplantation into the injured spinal cord. J Neurotrauma 27:1685-1695. Hill C, Harrison BJ, Rau KK, Hougland MT, Bunge MB, Mendell LM, Petruska JC (2010) Skin incision induces expression of axonal regeneration-related genes in spinal sensory neurons. Pain 11:1066-1073. Kirschner D, Avila-Carey R, Gamez Sazo R, Luoma A, Enzman G, Agrawal D, Inouye H, Bunge MB, Kocsis JD, Peters A, Whittemore S (2010) Rapid assessment of internodal myelin integrity in CNS tissue. J Neurosci Res 88(4):712-21. Harper MM, Adamson L, Blits B, Bunge MB, Grozdanic SD, Sakaguchi DS (2009) Brain-derived neurotrophic factor released from engineered mesenchymal stem cells attenuates glutamate- and hydrogen peroxide-mediated death of staurosporine-differentiated RGC-5 cells. Exp Eye Res. 89:538-548.

Fortun J, Puzis R, Pearse D, Gage FH, Bunge MB (2009) Muscle injection of AAV-NT3 promotes anatomical reorganization of CST axons and improves behavioral outcome following SCI. J Neurotrauma 26:941-953. Monje PV, Rendon S, Athauda G, Bates M, Wood PM, Bunge MB (2009) Non-antagonistic relationship between mitogenic factors and cAMP in adult Schwann cell re-differentiation. Glia 57 (9):947-961. Pinzon A, Marcillo A, Quintana A, Stamler S, Bunge MB, Bramlett HM, Dietrich WD (2008) A re-assessment of minocycline as a neuroprotective agent in a rat spinal cord contusion model. Brain Res. 1243:146-151. Pinzon A, Marcillo A, Pabon D, Bramlett HM, Bunge MB, Dietrich WD (2008) A re-assessment of erythropoietin as a neuroprotective agent following rat spinal cord compression or contusion injury. Exp Neurol. 213:129-136. Golden KL, Pearse DD, Blits B, Garg M, Oudega M, Wood PM, Bunge MB (2007) Transduced Schwann cells promote axon growth and myelination after spinal cord injury. Exp Neurol. 207:203-217. Hill CE, Hurtado A, Blits B, Bahr BA, Wood PM, Bunge MB (2007) Early necrosis and apoptosis of Schwann cells transplanted into the injured rat spinal cord. Europ J Neurosci. 26:1433-1445. Lane MA, Truettner JS, Brunschwig J-P, Gomez A, Bunge MB, Dietrich WD, Dziegielewska KM, Ek CJ, VandeBerg JL, Saunders NR (2007) Age-related differences in the local cellular and molecular responses to injury in developing spinal cord of the opossum, Monodelphis domestica. Europ J Neurosci 25:1725-1742. Pearse DD, Sanchez AR, Pereira FC, Andrade CM, Puzis R, Pressman Y, Golden KL, Kitay BM, Blits B, Wood PM, Bunge MB (2007) Transplantation of Schwann cells and/or olfactory ensheathing glia into the contused

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spinal cord: survival, migration, axon association and functional recovery, Glia 55:976-1000. Wanner IB, Mahoney J, Jessen KR, Wood PM, Bates M, Bunge MB (2006) Invariant mantling of growth cones by Schwann cell precursors characterize growing peripheral nerve fronts. Glia 54:424-438. Moon LDF, Madani R, Vassali J.-D, Bunge MB (2006) Neuronal overexpression of tissue-type plasminogen activator does not enhance sensory axon regeneration or locomotor recovery following dorsal hemisection of adult mouse thoracic spinal cord. J Neurosci Res. 84:1245-54. Casella GT, Bunge MB, Wood PM (2006) Endothelial cell loss is not a major cause of neuronal and glial cell death following contusion injury of the spinal cord. Exp Neurol. 202:8-20. (Mention on cover)

Moon LDF, Leasure JL, Gage FH, Bunge MB (2006) Motor enrichment sustains hindlimb movement recovered after spinal cord injury and glial transplantation. Rest Neurol Neurosci 24:147-161.

Hill CE, Moon LDF, Wood PM, Bunge MB (2006) Labeled Schwann cell transplantation: Cell loss, host Schwann cell replacement and strategies to enhance survival. Glia 53:338-343. Monje PV, Bunge M, Wood PM (2006) Cyclic AMP synergistically enhances neuregulin-dependent ERK and Akt activation and cell cycle progression in Schwann cells. Glia 53:649-659. Blits B, Kitay BM, Farahvar A, Caperton CV, Dietrich WD, Bunge MB (2005) Lentiviral vector-mediated transduction of neural progenitor cells before implantation into injured spinal cord and brain to detect their migration, deliver neurotrophic factors and repair tissue. Rest Neurol Neurosci 23:313-324. Cao Q, Xu X-M, DeVries WH, Enzman GU, Ping P, Tsoulfas P, Wood PM, Bunge MB, Whittemore SR (2005) Functional recovery in traumatic spinal cord injury after transplantation of multineurotrophin-expressing glial-restricted precursor cells. J Neurosci 25:6947-6957.

Barakat DJ, Gaglani SM, Neravetla SR, Sanchez AR, Andrade CM, Pressman Y, Puzis R, Garg MS, Bunge MB, Pearse DD (2005) Survival, integration and axon growth support of glia transplanted into the chronically contused spinal cord. Cell Transplantation 14:225-240. Anderson DK, Beattie M, Blesch A, Bresnahan J, Bunge MB, Dietrich D, Dietz V, Dobkin B, Fawcett J, Fehlings M, Fischer I, Grossman R, Guest J, Hagg T, Hall ED, Houle J, Kleitman N, McDonald J, Murray M, Privat A, Reier P, Steeves J, Steward O, Tetzlaff W, Tuszynski MH, Waxman SG, Whittemore S, Wolpaw J, Young W, Zheng B (2005) Recommended guidelines for studies of human subjects with spinal cord injury. Spinal Cord 43:453-458. Fouad K, Schnell L, Bunge MB, Schwab ME, Liebscher T, Pearse DD (2005) Combining Schwann cell bridges and olfactory ensheathing glia grafts with chondroitinase promotes locomotor recovery after complete transection of the spinal cord. J Neurosci 25:1169-1178. Talbott JF, Loy DN, Liu Y, Qiu MS, Bunge MB, Rao MS, Whittemore SR (2005) Endogenous Nkx2.2+/Olig2+ oligodendrocyte precursor cells fail to remyelinate the demyelinated adult rat spinal cord in the absence of astrocytes. Exp Neurol 192:11-24. Grimpe B, Pressman Y, Lupa MD, Horn KP, Bunge MB, Silver J (2005) The role of proteoglycans in Schwann cell/astrocyte interactions and in regeneration failure at PNS/CNS interfaces. Mol Cell Neurosci 28:18-29. Fregien NL, White LA, Bunge MB, Wood PM (2004) Forskolin increases neuregulin receptors in human Schwann cells without increasing receptor mRNA. Glia 49:24-35.


Meijs MFL, Timmers L, Pearse DD, Tresco PA, Bates ML, Joosten EAJ, Bunge MB, Oudega M (2004) Basic fibroblast growth factor promotes neuronal survival but not behavioral recovery in the transected and Schwann cell implanted rat thoracic spinal cord. J Neurotrauma 21:1415-1430. Pearse DD, Pereira FC, Stolyarova A, Barakat DJ, Bunge MB (2004) Inhibition of tumour necrosis factor-alpha by antisense targeting produces immunophenotypical and morphological changes in injury-activated microglia and macrophages. Eur J Neurosci 20:3387-3396. Pearse DD, Marcillo AE, Oudega M, Lynch MP, Wood PM, Bunge MB (2004) Transplantation of Schwann cells and olfactory ensheathing glia after spinal cord injury: Does pretreatment with methylprednisolone and interleukin-10 enhance recovery? J Neurotrauma 21:1223-1239. Casella GT, Bunge MB, Wood PM (2004) Improved immunocytochemical identification of neural, endothelial, and inflammatory cell types in paraffin-embedded injured adult rat spinal cord. J Neurosci Methods 139:1-11. Pearse DD, Pereira FC, Marcillo AE, Bates ML, Berrocal YA, Filbin MT, Bunge MB (2004) cAMP and Schwann cells promote axonal growth and functional recovery after spinal cord injury. Nat Med 10:610-616. Aimone JB, Leasure JL, Perreau VM, Thallmair M and the Christopher Reeve Paralysis Foundation Research Consortium (2004) Spatial and temporal gene expression profiling of the contused rat spinal cord. Exp Neurol 189:204-221. Pearse DD, Chatzipanteli K, Marcillo AE, Bunge MB, Dietrich WD (2003) Comparison of iNOS inhibition by antisense and pharmacological inhibitors after spinal cord injury. J Neuropathol Exp Neurol 62:1096-1107. Blits B, Oudega M, Boer GJ, Bunge MB, Verhaagen J (2003) Adeno-associated viral vector-mediated neurotrophin gene transfer in the injured adult rat spinal cord improves hindlimb function. Neuroscience 118:271-281.

Plant GW, Christensen CL, Oudega M, Bunge MB (2003) Delayed transplantation of olfactory ensheathing glia promotes sparing/regeneration of supraspinal axons in the moderately contused adult rat spinal cord. J Neurotrauma 20:1-16. Takami T, Oudega M, Bates ML, Wood PM, Kleitman N, Bunge MB (2002) Schwann cell but not olfactory ensheathing glia transplants improve hindlimb locomotor performance in the moderately contused adult rat thoracic spinal cord. J Neurosci 22:6670-6681.

Plant GW, Currier PF, Cuervo EP, Bates ML, Pressman Y, Bunge MB, Wood PM (2002) Purified adult ensheathing glia fail to myelinate axons under culture conditions that enable Schwann cells to form myelin. J Neurosci 22:6083-6091.

Takami T, Oudega M, Bethea JR, Wood PM, Kleitman N, Bunge MB (2002) Methylprednisolone and interleukin-10 reduce gray matter damage in the contused Fischer rat thoracic spinal cord but do not improve functional outcome. J Neurotrauma 19:653-666.

von Euler M, Janson AM, Larsen JO, Sieger A, Forno L, Bunge MB, Sundstrom E (2002) Spontaneous axonal regeneration in rodent spinal cord after ischemic injury. J Neuropathol Exp Neurol 61:64-75.

Casella GT, Marcillo A, Bunge MB, Wood PM (2002) New vascular tissue rapidly replaces neural parenchyma and vessels destroyed by a contusion injury to the rat spinal cord. Exp Neurol 173:63-76.


Oudega M, Gautier SE, Chapon P, Fragoso M, Bates ML, Parel J-M, Bunge MB (2001) Axonal regeneration into Schwann cell grafts within resorbable poly(α-hydroxyacid) guidance channels in the adult rat spinal cord. Biomaterials 22:1125-1136.

Plant GW, Bates ML, Bunge MB (2001) Inhibitory proteoglycan immunoreactivity is higher at the caudal than the rostral Schwann cell graft-transected spinal cord interface. Molec Cell Neurosci 17:471-487.

Yan HL, Bunge MB, Wood PM, Plant GW (2001) Mitogenic response of adult rat olfactory ensheathing glia to four growth factors. Glia 33:334-342.

Oudega M, Vargas CG, Weber AB, Kleitman N, Bunge MB (1999) Long-term effects of methylprednisolone following transection of adult rat spinal cord. Eur J Neurosci 11:2453-2464.

Xu XM, Zhang S-X, Li H, Aebischer P, Bunge MB (1999) Regrowth of axons into the distal spinal cord through a Schwann-cell-seeded mini-channel implanted into hemisected adult rat spinal cord. Eur J Neurosci 11:1723-1740.

Emery E, Aldana P, Bunge MB, Puckett W, Srinivasan A, Keane RW, Bethea J, Levi ADO (1998) Apoptosis after traumatic human spinal cord injury. J Neurosurg 89:911-920

Gautier SE, Oudega M, Fragoso M, Chapon P, Plant GW, Bunge MB, Parel J-M (1998) Poly( -hydroxyacids) for application in the spinal cord: Resorbability and biocompatibility with adult rat Schwann cells and spinal cord. J Biomed Mater Res 42:642-654.

Fernandez-Valle C, Wood PM, Bunge MB (1998) Localization of focal adhesion kinase in differentiating Schwann cell/neuron cultures. Microsc Res Tech Special issue: Myelin formation and maintenance. Martini R (ed). Wiley-Liss, New York 41:416-430 (original data). Ramón-Cueto A, Plant GW, Avila J, Bunge MB (1998) Long-distance axonal regeneration in the transected adult rat spinal cord is promoted by olfactory ensheathing glia transplants. J Neurosci 18:3803-3815.

Menei P, Montero-Menei C, Whittemore SR, Bunge RP, Bunge MB (1998) Schwann cells genetically modified to secrete human BDNF promote enhanced axonal regrowth across transected adult rat spinal cord. Eur J Neurosci 10:607-621.

Guest JD, Rao A, Bunge MB, Bunge RP (1997) The ability of human Schwann cell grafts to promote regeneration in the transected nude rat spinal cord. Exp Neurol 48:502-522. Guest JD, Hesse D, Schnell L, Schwab ME, Bunge MB, Bunge RP (1997) The influence of IN-1 antibody and acidic FGF-fibrin glue on the response of injured corticospinal tract axons to human Schwann cell grafts. J Neurosci Res 50:888-905.

Oudega M, Xu XM, Guénard V, Kleitman N, Bunge MB (1997) A combination of insulin-like growth factor-I and platelet-derived growth factor enhances myelination but diminishes axonal regeneration into Schwann cell grafts in the adult rat spinal cord. Glia 19:247-258.

Xu XM, Chen A, Guénard V, Kleitman N, Bunge MB (1997) Bridging Schwann cell transplants promote axonal regeneration from both the rostral and caudal stumps of transected adult rat spinal cord. J Neurocytol 26:1-16.

Fernandez-Valle C, Gorman D, Gomez AM, Bunge MB (1997) Actin plays a role in both changes in cell shape and gene expression associated with Schwann cell myelination. J Neuroscience 17:241-250.


Chen A, Xu XM, Kleitman N, Bunge MB (1996) Methylprednisolone administration improves axonal regeneration into Schwann cell grafts in transected adult rat thoracic spinal cord. Exp Neurol 138:261-276.

Shihabuddin LS, Brunschwig J-P, Holets VR, Bunge MB, Whittemore SR (1996) Induction of mature neuronal properties in immortalized neuronal precursor cells following grafting into the neonatal CNS. J Neurocytol 25:101-111. Fernandez-Valle C, Bunge RP, Bunge MB (1995) Schwann cells degrade myelin and proliferate in the absence of macrophages: evidence from in vitro studies of Wallerian degeneration. J Neurocytol 24:667-679.

Xu XM, Guénard V, Kleitman N, Aebischer P, Bunge MB (1995) A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord. Exp Neurol 134:261-272.

Obremski VJ, Bunge MB (1995) Addition of purified basal lamina molecules enables Schwann cell ensheathment of sympathetic neurites in culture. Dev Biol 168:124-137.

Xu XM, Guénard V, Kleitman N, Bunge MB (1995) Axonal regeneration into Schwann cell-seeded guidance channels grafted into transected adult rat spinal cord. J Comp Neurol 351:145-160.

Fernandez-Valle C, Gwynn L, Wood P, Carbonetto S, Bunge MB (1994) Anti-ß1 integrin antibody inhibits Schwann cell myelination. J Neurobiol 25:1207-1226.

Paino CL, Fernandez-Valle C, Bates ML, Bunge MB (1994) Regrowth of axons in lesioned adult rat spinal cord: Promotion by implants of cultured Schwann cells. J Neurocytol 23:433-452. Bunge MB, Holets VR, Bates ML, Clarke TS, Watson BD (1994) Characterization of photochemically induced spinal cord injury in the rat by light and electron microscopy. Exp Neurol 127:76-93.

Fernandez-Valle C, Fregien N, Wood PM, Bunge MB (1993) Expression of the protein zero myelin gene in axon-related Schwann cells is linked to basal lamina formation. Development 119:867-880.

Obremski VJ, Wood PM, Bunge MB (1993) Fibroblasts promote Schwann cell basal lamina deposition in the absence of neurons in culture. Dev Bio1 26:119-134.

Obremski VJ, Johnson MI, Bunge MB (1993) Fibroblasts are required for Schwann cell basal lamina deposition and ensheathment of unmyelinated sympathetic neurites in culture. J Neurocytol 22:102-117. Quencer RM, Bunge RP, Bunge MB, Calancie B, Fitzpatrick S, Green BA, Holets V (1992) Progress in the characterization and treatment of the injured spinal cord: highlights of the second biennial International Coalition on Spinal Cord Injury. Am J Neuroradiol 13:1027-1031.

Paino CL, Bunge MB (1991) Induction of axon growth into Schwann cell implants grafted into lesioned adult rat spinal cord. Exp Neurol 114:254-257.

Ard MD, Bunge MB, Wood PM, Schachner M, Bunge RP (1991) Retinal neurite growth on astrocytes is not modified by extracellular matrix, anti-Ll antibody, or oligodendrocytes. Glia 4:70-82.

Kuhlengel KR, Bunge MB, Bunge RP (1990) Implantation of cultured sensory neurons and Schwann cells into lesioned neonatal rat spinal cord. I. Methods for preparing implants from dissociated cells. J Comp Neurol. 293:63-73.


Kuhlengel KR, Bunge MB, Bunge RP, Burton H (1990) Implantation of cultured sensory neurons and Schwann cells into lesioned neonatal rat spinal cord. II. Implant characteristics and examination of corticospinal tract growth. J Comp Neurol. 293:74-91.

Bunge RP, Bunge MB, Bates M (1989) Movements of the Schwann cell nucleus implicates progression of the inner (axon-related) Schwann cell process during myelination. J Cell Biol. 109:273-284.

Clark MB, Bunge MB (1989) Cultured Schwann cells assemble normal-appearing basal lamina only when they ensheathe axons. Dev Biol. 133:393-404.

Bunge MB, Wood PM, Tynan LB, Bates ML, Sanes JR (1989) Perineurium originates from fibroblasts: demonstration in vitro with a retroviral marker. Science 243:229-231.

Eldridge CF, Bunge MB, Bunge RP (1989) Differentiation of axon-related Schwann cells in vitro: II. Control of myelin formation by basal lamina. J Neurosci. 9:625-638.

Eldridge CF, Bunge RP, Bunge MB (1988) Effects of cis-4-hydroxy-L-proline, an inhibitor of Schwann cell differentiation, on the secretion of collagenous and non-collagenous proteins by Schwann cells. Exp Cell Res. 174:491-501.

Bray D, Bunge MB, Chapman K (1987) Geometry of isolated sensory neurons in culture: effects of embryonic age and culture substratum. Exp Cell Res. 168:127-137.

Ard MD, Bunge RP, Bunge MB (1987) A comparison of the Schwann cell surface and Schwann cell extracellular matrix as promoters of neurite growth. J Neurocytol. 16:539-555.

Eldridge CF, Bunge MB, Bunge RP, Wood PM (1987) Differentiation of axon-related Schwann cells in vitro. I. Ascorbic acid regulates basal lamina assembly and myelin formation. J Cell Biol 105:1023-1034.

Bunge MB, Bunge RP (1986) Linkage between Schwann cell extracellular matrix production and ensheathment function. Ann NY Acad Sci. 486:241-247.

Ratner N, Elbein A, Bunge MB, Porter S, Bunge RP, Glaser L (1986) Specific asparagine-linked oligosaccharides are not required for certain neuron-neuron and neuron-Schwann cell interactions. J Cell Biol. 103:159-170.

Bunge RP, Bunge MB, Eldridge CF (1986) Linkage between axonal ensheathment and basal lamina production by Schwann cells. Ann Rev Neurosci. 9:305-328.

Bunge MB (1986) The axonal cytoskeleton: its role in generating and maintaining cell form. TINS 9:477-482 (Invited review for special issue)

Roufa D, Bunge MB, Johnson MI, Cornbrooks CJ (1986) Variation in content and function of non-neuronal cells in the outgrowth of sympathetic ganglia from embryos of differing age. J Neurosci 6:790-802.

Argiro V, Bunge MB, Johnson MI (1985) A quantitative study of growth cone filopodial extension. J Neurosci Res. 13:149-162.

Argiro V, Bunge MB, Johnson MI (1984) Correlation between growth cone form and movement and their dependence on neuronal age. J Neurosci 4:3051-3062.

Bunge RP, Bunge MB (1983) Interrelationship between Schwann cell function and extracellular matrix production. TINS 6:499-505.


Roufa DG, Johnson MI, Bunge MB (1983) Influence of ganglion age, non-neuronal cells and substratum on neurite outgrowth in culture. Develop Biol 99:225-239.

Bunge MB, Williams AK, Wood PM (1982) Neuron-Schwann cell interaction in basal lamina formation. Dev Biol. 92:449-460.

Honchar MP, Bunge MB, Agrawal HC (1982) In vivo phosphorylation of neurofilament proteins in the central nervous system of immature rat and rabbit. Neurochemical Res. 7:365-372.

Bray D, Bunge MB (1981) Serial analysis of microtubules in cultured rat sensory axons. J Neurocytol 10:589-605.

Bunge MB, Williams AK, Wood PM, Uitto J, Jeffrey JJ (1980) Comparison of nerve cell and nerve cell plus Schwann cell cultures, with particular emphasis on basal lamina and collagen formation. J Cell Biol 84:184-202.

Okada E, Bunge RP, Bunge MB (1980) Abnormalities expressed in long term cultures of dorsal root ganglia from the dystrophic mouse. Brain Research 194:455-470.

Moya F, Bunge MB, Bunge RP (1980) Schwann cells proliferate but fail to differentiate in defined medium. Proc Natl Acad Sci USA 77:6902-6906.

Bunge RP, Bunge MB (1978) Evidence that contact with connective tissue matrix is required for normal interaction between Schwann cells and nerve fibers. J Cell Biol. 78:943-950. “Rapid Communication”.

Bunge RP, Bunge MB, Cochran M (1978) Some factors influencing the proliferation and differentiation of myelin-forming cells. Neurology 28:59-67 (part 2).

Bunge MB (1977) Initial endocytosis of peroxidase or ferritin by growth cones of cultured nerve cells. J Neurocytol. 6:407-439.

Rees RP, Bunge MB, Bunge RP (1976) Morphological changes in the neuritic growth cone and target neuron during synaptic junction development in culture. J Cell Biol. 68:240-263.

Blank WF Jr., Bunge MB, Bunge RP (1974) The sensitivity of the myelin sheath, particularly the Schwann cell-axolemmal junction, to lowered calcium levels in cultured sensory ganglia. Brain Research 67:503-518. Bunge MB (1973) Fine structure of nerve fibers and growth cones of isolated sympathetic neurons in culture. J Cell Biol. 56:713-735.

Brosnan CF, Bunge MB, Murray MR (1970) The response of lysosomes in cultured neurons to chlorpromazine. J Neuropath Exper Neurol. 29:337-353.

Bunge MB, Bunge RP, Peterson ER, Murray MR (1967) A light and electron microscope study of long-term organized cultures of rat dorsal root ganglia. J Cell Biol. 32:439-46.

Masurovsky EB, Bunge MB, Bunge RP (1967) Cytological studies of organotypic cultures of rat dorsal root ganglia following X-irradiation in vitro. I. Changes in neurons and satellite cells. J Cell Biol. 32:467-496.

Masurovsky EB, Bunge MB, Bunge RP (1967) Cytological studies of organotypic cultures of rat dorsal root ganglia following X-irradiation in vitro. II. Changes in Schwann cells, myelin sheaths, and nerve fibers. J Cell Biol. 32:497-518.


Bunge MB, Bunge RP, Peterson ER (1967) The onset of synapse formation in spinal cord cultures as studied by electron microscopy. Brain Research 6:728-749.

Bunge RP, Bunge MB, Peterson ER (1965) An electron microscope study of cultured rat spinal cord. J Cell Biol. 24:161-191.

Koenig H, Bunge MB, Bunge RP (1962) Nucleic acid and protein metabolism in white matter. Observations during experimental demyelination and remyelination; a histochemical and autoradiographic study of spinal cord of the adult cat. Arch Neurol. 6:177-193.

Bunge MB, Bunge RP, Pappas GD (1962) Electron microscopic demonstration of connections between glia and myelin sheaths in the developing mammalian central nervous system. J Cell Biol. 12:448-453.

Bunge MB, Bunge RP, Ris H, (1961) Ultrastructural study of remyelination in an experimental lesion in adult cat spinal cord. J Biophysic and Biochem Cytol. 10:67-94.

Bunge RP, Bunge MB, Ris H (1960) Electron microscopic study of demyelination in an experimentally induced lesion in adult cat spinal cord. J Biophysic and Biochem Cytol.7:685-696.

Bunge MB, Schloesser LL, Schilling RF (1956) Intrinsic factor studies. IV. Selective absorption and binding of cyanocobalamin by gastric juice in the presence of excess pseudovitamin B12 or 5-6-Dimethylbenzamidazole. J Lab and Clin Med. 48:735-744.

Bunge MB, Schilling RF (1956) Intrinsic factor studies. VI. Competition for the vit. B12 binding sites offered by analogues of the vitamin. Proc Soc Exper Biol and Med. 96:587-592.

19. Other works, publications and abstracts: PUBLISHED ABSTRACTS 2011 abstracts not yet entered

Hutson TH, Moon LDF, Van Kesteren RG, Iffland K, Torres-Muńoz J, Bowen CP, Almone JB, Buchser WJ, Lemmon VP, Bixby JL, Smit AB, Gage FH, Bunge MB (2013) Laser microdissection of in vitro regenerating spinal neurons identifies genes including ptpn2 that promote neurite outgrowth and axon regeneration. The 43rd Annual Meeting for the Society for Neuroscience. Lee YS, Wu S, Sidhu I, Livingston Arinzeh T, Bunge MB (2013) Novel conduits for Schwann cell induced spinal cord repair. Society for Biomaterials Meeting, Newark, NJ USA. Kanno, H, Pressman Y, Moody A, Berg R, Muir E, Rogers, J, Ozawa H, Itoi, E, Pearse DD, Bunge, MB (2013) Combined engineering of Schwann cell implants to secrete neurotrophin and chondroitinase promotes axonal regeneration and locomotion after spinal cord injury. Orthopedic Research Society, 2013.

Datto J, Bastidas J, Conner L, Gagani A, Miller N, Lee I, Marcillo AE, Wood PM, Guest JD, Bunge MB, Dietrich WD, Pearse DD (2012) Gender responses to experimental spinal cord injury and a cell therapeutic. Military Health System Research Symposium, Ft. Lauderdale, FL USA. Williams RR, Pearse DD, Bunge MB (2012) The importance of implanted Schwann cell and host astrocyte interactions in providing a permissive environment for brainstem axon regeneration and improved hindlimb movements after SCI. The 42nd Annual Meeting for the Society of Neuroscience. Lee YS, Wu S, Arinzeh TL, Bunge MB (2012) Aligned fibrous conduits for Schwann cell induced spinal cord repair. The 42nd Annual Meeting for the Society of Neuroscience.


Kanno H, Pressman Y, Moody A, Berg R, Pearse DD, Bunge MB (2012) Combined engineering of Schwann cell implants to secrete neurotrophin and chondroitinase promotes axonal regeneration and locomotion after spinal cord injury. The 42nd Annual Meeting for the Society of Neuroscience, New Orleans, LA USA. (This was considered as a “Hot Topic”.)

Hill CE, Brodak DM, Bunge MB (2010) Comparison of cultured SCs and freshly isolated pre-degenerated peripheral nerve following transplantation into the contused rat spinal cord. The 40th Annual Meeting for the Society of Neuroscience, San Diego, CA USA. Williams RR, Pearse DD, Bunge MB (2010) Expression of the developmental transcription factor MASH-1 in the brainstem enhances the regeneration of noradrenergic axons across a Schwann cell bridge. The 40th Annual Meeting for the Society of Neuroscience, San Diego, CA USA. Monje PV, Soto J, Bunge MB, Wood P (2009) Cyclic AMP promotes Schwann cell proliferation and differentiation through different signaling mechanisms. The 39th Annual Meeting for the Society of Neuroscience. Oudega M, Rahiem ST, Wendell DF, Hurtado A, Bunge MB (2009) Locomotor and sensory function improvement following Schwann cell transplantation combined with caudal injections of lentiviral vectors encoding for the bi-functional neurotrophin D15A in the contused adult rat thoracic spinal cord. The 39th Annual Meeting for the Society of Neuroscience. Hill CE, Brodak DM, Hurtado A, Oudega M, Wood PM, Bunge MB (2009) Identification and quantification of proliferating Schwann cells following transplantation into the injured spinal cord. The 39th Annual Meeting for the Society of Neuroscience.

Pearse DD, Louro J, Mawson DM, Perez MV, Darquea F, Sanchez AR, Andrade CM, Ghosh M, Wood PM, Bunge MB, Noga BR, Hentall IM, Yu F (2009) Cyclic AMP mediated serotonergic axon growth and functional recovery after SCI: continuous versus transient elevation, 13th International Symposium on Neural Regeneration, Pacific Grove, CA USA.

Flora G, Joseph G, Patel A, Alex G, Maggio D, Barakat DJ, Louro J, Nerevetla S, Bunge MB, Pearse DD (2008)

The implantation of neurotrophin-secreting Schwann cells and rolipram administration for chronic spinal cord injury repair. International Society for Cellular Therapy, Miami, FL USA.

Pearse DD, Flora G, Joseph G, Fenton S, Singh A, Bleicher D, Barakat DJ, Luoro J, Garg M, Bunge MB (2008)

Combining transduced Schwann cells and cAMP elevation for the promotion of functional recovery after subacute spinal cord injury. International Society for Cellular Therapy, Miami, FL USA.

Sakaguchi DS, Harper MM, Adamson L, Blits B, Bunge MB, Grozdanic SD (2008) Brain-derived neurotrophic factor (BDNF) released from engineered mesenchymal stem cells (MSCs) attenuates glutamate- and hydrogen peroxide-mediated death of staurosporine differentiated RGC-5S. The Association for Research in Vision and Opthalmology.

Garg MS, Patel M, Puzis R, Alexander ME, Pereira FC, Bunge MB, Pearse DD (2007) MDP (muramyl dipeptide) improves histological and functional outcome in rats with contusive spinal cord injury (SCI), Immunology 2007: American Association of Immunologists, Miami, FL USA.

Bunge MB (2007) Novel combination strategies to repair the injured spinal cord. The 37th Annual Meeting for the Society of Neuroscience (Symposium speaker).


Fortun J, Thuret S, Genoud S, Schroter S, Gage F, Bunge MB (2007) Retrograde transport of adeno-associated virus from triceps to the cervical spinal cord. The 37th Annual Meeting for the Society of Neuroscience. Hill CE, Raffa SJ, Hurtado A, Bunge MB (2007) Inhibition of necrosis with the calpain inhibitor MDL28170 enhances the survival of Schwann cells transplanted into the injured adult rat spinal cord. The 37th Annual Meeting for the Society of Neuroscience.

Kirschner DA, Avila RL, Luoma AM, Inouye H, Gamez E, Bunge MB, Kocsis JD, Peters A, Whittemore S (2007) A novel rapid and quantitative assessment of demyelination and remyelination in spinal cord injury models.

Lane MA, Truettner JS, Brunschwig J-P, Gomez A, Bunge MB, Dietrich WD, Dziegielewska KM, Ek CJ, VandeBerg JL, Saunders NR (2007) Mechanisms of recovery following complete spinal transection in postnatal opossums (Monodelphis domestica). International Brain Research Organization.

Sakaguchi DS, Harper MM, Grozdanic SG, Blits B, Kuehn MH, Zamzow D, Buss JE, Reger RL, Prockop DJ, Bunge MB, Kwon YH, Kardon RH (2007) Intraocular transplantation of BDNF mesenchymal stem cells preserves visual function and retinal morphology in glaucomatous rat eyes. The 37th Annual Meeting for the Society of Neuroscience. DD Pearse, Blits B, Joseph G, Mawson DH, Louro J, Bustin D, Benson DM, Parada LF, Bunge MB (2006) Constitutive activation of the MAPK pathway promotes regeneration after complete spinal cord transection. The 36th Annual Meeting for the Society of Neuroscience, Atlanta, GA USA.

Fortun J, Wood PM, Bunge MB (2006) Laminin protects Schwann cells from apoptosis induced by substratum

detachment. The 36th Annual Meeting for the Society of Neuroscience, Atlanta, GA USA.

Hill CE, Hurtado A, Wood PM, Bunge MB (2006) Strategies to improve Schwann cell (SC) survival for transplantation. The 36th Annual Meeting for the Society of Neuroscience, Atlanta, GA USA.

Hurtado A, Pearse DD, Blits B, Puentes R, Villalobos M, Bates PL, Bunge MB, Oudega M (2006) Endogenous Schwann cells genetically modified in vivo to overexpress neurotrophins migrate into the moderately contused rat thoracic spinal cord and affect functional outcome. The 36th Annual Meeting for the Society of Neuroscience, Atlanta, GA USA.

Petruska JC, Moon LD, Lee Y, Bunge MB, Mendell LM (2006) Changes in NGF-and pain-related genes during collateral sprouting revealed by microarray analysis. The 36th Annual Meeting for the Society of Neuroscience, Atlanta, GA USA.

Garg MS, Pearse DD, Pressman Y, Puzis R, Bates ML, Wood PM, Bunge MB (2005) Schwann cell and olfactory ensheathing glia myelination: modulation by cyclic adenosine monophosphate (cAMP) in vitro and in vivo, The 12th Annual Conference of the American Society for Neural Transplantation & Repair, Clearwater Beach, USA.

Bunge MB, Sanchez AR, Pereira FC, Puzis R, Pressman Y, Golden KL, Kitay B, Blits B, Wood PM, Pearse DD (2005) Delayed transplantation of Schwann cells and/or olfactory ensheathing glia into the contused spinal cord: survival, migration and axon association. The 35th Annual Meeting for the Society of Neuroscience, Washington, DC USA.

Hill CE, Hurtado A, Blits B, Bahr BA, Bunge MB, Wood PM, Oudega M (2005) Early death of labeled

Schwann cells following transplantation into the contused adult rat spinal cord: a quantitative analysis of cell survival, mechanisms of cell loss and host Schwann cell invasion. The 35th Annual Meeting for the Society of Neuroscience, Washington, DC USA.


Monje P, Margitich I, Bunge MB, Wood PM (2005) Role of cAMP in the regulation of neuregulin signaling in Schwann cells. The 35th Annual Meeting for the Society of Neuroscience, Washington, DC USA.

Moon LDF, Torres-Munoz JE, Petito CK, Aimone JB, Lein ES, Gage FH, Bunge MB (2005) Identification of genes expressed by spinal cord neurons regenerating an axon into a Schwann cell bridge transplanted after thoracic transaction. The 35th Annual Meeting for the Society of Neuroscience, Washington, DC USA. Pinzon A, Marcillo AE, Ospina D, Quintana A, Pearse DD, Bunge MB, Dietrich WD (2005) Assessment of erythropoietin neuroprotective effects in a contusive cervical spinal cord injury model in rats, The 23rd Annual National Neurotrauma Society Meeting, Washington, DC USA.

Bunge MB, and Pearse DD (2005) cAMP and Schwann cells promote regeneration and recovery after SCI, The 23rd Annual National Neurotrauma Society Meeting, Washington, DC USA.

Blits B, Joseph G, Mawson DH, Louro J, Matheny S, Benson D, Lin L, Parada LF, Bunge MB, Pearse DD (2005) Gene transfer of constitutively-activated MEK or ERK at the neuronal soma by adeno-associated viral vectors to induce axonal regrowth across Schwann cell bridges implanted into the completely transected rat thoracic spinal cord, Speaker at the 11th International Symposium on Neural Regeneration, Pacific Grove, CA USA. Berrocal YA, Pearse DD, Andrade CM, Bunge MB, Eaton MJ (2005) Loss of central inhibition and appearance of neuronal hyperexcitability: Implications for behavioral hypersensitivity after contusive spinal cord inujury (SCI) in rats. The 24th Annual Scientific Meeting of the American Pain Society, Boston, MA USA. Pearse DD, Pereira FC, Marcillo AE, Berrocal YA, Bunge MB (2004) The phosphodiesterase type IV inhibitor, rolipram, prevents axon loss after contusive spinal cord injury (SCI). The 30th Annual ASIA Scientific Meeting, Denver, CO USA. Berrocal YA, Pearse DD, Andrade CM, Gomez-Marin O, Bunge MB, Eaton MJ, (2004) Evaluation of the sensory system in a commonly used contusive spinal cord injury (SCI) model for assessment of regenerative cellular therapies. The 11th Annual Conference of the American Society for Neural Transplantation & Repair, Clearwater Beach, CA USA.

Pearse DD, Pereira FC, Puzis R, Blits B, Sanchez AR, Viera RT, Wood PM, Bunge MB (2004) Transplantation of Schwann cells and/or olfactory ensheathing glia into the contused spinal cord: survival, migration and axon association. The 11th Annual Conference of the American Society for Neural Transplantation & Repair, Clearwater Beach, CA USA.

Pearse DD, Blits B, Bunge MB, Wood PM, Sanchez AR, Hurtado A, Lopez E, Oudega M (2004) Minimally invasive strategies for administration of genetically-modified glia to the contused spinal cord. The 7th Annual Meeting for The American Society of Gene Therapy, Minneapolis, MN USA.

Pearse DD, Lo TD, Cho, KS, Marcillo AE, Bunge MB, Dietrich WD (2004) Histopathological and behavioral characterization of a novel cervical contusion injury model. The 7th International Neurotrauma Symposium, Adelaide, Australia.

Pearse DD, Periera FC, Sanchez, AR, Blits B, Marcillo AE, Bunge MB (2004) The survival, migration and axon association of glial cells transplanted in the contused spinal cord. The 2nd International Congress on Neuroregeneration, Rio de Janeiro, Brazil.

Pearse DD, Lo TD, Cho, KS, Marcillo AE, Bunge MB, Dietrich WD (2004) Experimental graded cervical contusion in rats using spinal cord displacement: pathology and behavioral recovery. The 22nd Annual National Neurotrauma Society Meeting, San Diego, CA USA.


Golden KL, Pearse DD, Blits B, Oudega M, Wood PM, Bunge MB (2004) Axonal regeneration into adenoviral or lentiviral vector-transduced Schwann cell grafts exhibiting neurotrophin production following implantation into the contused rat spinal cord. The 34th Annual Meeting for the Society of Neuroscience, San Diego, CA USA.

Golden KL, Pearse DD, Blits B, Oudega M, Wood PM, Bunge MB (2004) Schwann cells genetically modified to secrete a bifunctional neurotrophin increase axon regeneration, The 7th Symposium on Biomaterials Science, New Brunswick, NJ USA.

Pearse DD, Blits B, Hurtado A, Lopez EP. Wood PM, Sanchez AR, Bunge MB, Oudega M, (2004) Dorsal roots: the road to the injured spinal cord for genetically modified glia to the contused spinal cord. The 34th Annual Meeting for the Society of Neuroscience, San Diego, CA USA. Monje PV, Bunge MB, Wood P (2004) Cyclic AMP controls cells cycle progression by modulating the duration of MEK-ERK activation in Schwann cells. The 34th Annual Meeting for the Society of Neuroscience, San Diego, CA USA.

Golden KL, Pearse DD, Blits B, Oudega M, Wood PM, Bunge MB (2004) Adenoviral and lentiviral vector transduction of grafted Schwann cells with a bifunctional neurotrophin to facilitate axon regeneration following contusive SCI. The 34th Annual Meeting for the Society of Neuroscience, San Diego, CA USA. Blits B, Caperton CV, Kitay BM, Corrales GC, Bunge MB (2004) Behavioral and histological analysis of CNTF, NF-3 and BDNF over expression in implanted neural progenitor cells mixed with Schwann cells into the injured rat spinal cord. The 34th Annual Meeting for the Society of Neuroscience, San Diego, CA USA. Pearse DD, Berrocal YA, Andrade CM, Khan A, Bunge MB, Eaton MJ (2004) Quantification of the integrity of the sensory system after severe contusive spinal cord injury using the neuronal activity marker, c-Fos. The 7th International Conference on the Mechanisms and Treatment of Neuropathic Pain, Bermuda. Berrocal YA, Pearse DD, Andrade CM, Bunge MB, Eaton MJ (2004) Temporal and Spatial Alterations in Neuromodulatory and Inhibitory Neurotransmitters after Spinal Cord Injury" The 7th International Conference on the Mechanisms and Treatment of Neuropathic Pain, Bermuda.

Berrocal YA, Pearse DD, Andrade CM, Bunge MB, Eaton MJ (2004) Behavioral Hypersensitivity after Severe Contusive Spinal Injury. The 7th International Conference on the Mechanisms and Treatment of Neuropathic Pain, Bermuda. Blits B, Gajavelli S, Hendriks WTJM, Verhaagen J, Bunge MB, Tsoulfas P (2003) Genetic modification of rat neural progenitor cells using lentiviral vectors. Keystone Symposium. Blits B, Gajavelli S, Hendriks W, Verhaagen J, Bunge MB, Tsoulfas P (2003) Lentiviral vector-mediated transduction of rat embryonic neural precursor cells. 6th Annual Meeting, American Society for Gene Therapy, Washington, DC USA. Blits B, Gajavelli S, Tsoulfas P, Bunge MB (2003) Transduction of rat embryonic stem cells to overexpress neurotrophic factors using lentiviral vectors. The 33rd Annaul Meeting for the Society for Neuroscience, New Orleans, LA USA. Chatzipanteli K, Pearse DD, Pereira FC, Bunge MB, Dietrich WD (2003) Targeting iNOS after contusive spinal cord injury abates detrimental pathophysiological processes. The 2003 Nature Biotechnology Winter Symposia, Miami, FL USA. Pearse DD, Pereira FC, Marcillo AE, Bates ML, Berrocal YA, Bunge MB (2003) Elevation of cAMP enhances regeneration and improves behavioral recovery in Schwann cell-grafted animals after spinal cord injury. The 33rd Annual Meeting for the Society for Neuroscience, New Orleans, LA USA.


Chatzipanteli K, Pearse DD, Marcillo AE, Bunge MB, Dietrich WD (2003) Antisense mediated inhibition of iNOS acutely promotes partial hindlimb recovery after spinal cord contusion. The 33rd Annual Meeting for the Society for Neuroscience, New Orleans, LA USA.

Leasure JL, Thallmair M, Perreau V (2003) The Christopher Reeve Paralysis Foundation Research Consortium. Gene expression profiling after contusive spinal cord injury, The 33rd Annual Meeting for the Society of Neuroscience, New Orleans, USA. Bunge MB, Pressman Y, Bates ML, Garg MS, Wood PM, Pearse DD (2003) Continuous cyclic AMP elevation by membrane permeable derivatives and phosphodiesterase inhibition act synergistically to increase myelination in DRGN-Schwann cell cultures. The 33rd Annual Meeting for the Society for Neuroscience, New Orleans, LA USA. Pearse DD, Chatzipanteli K, Marcillo AE, Bunge MB, Dietrich WD (2003) Molecular targeting with iNOS antisense oligodeoxynucleotides improves motor function after experimental spinal cord injury, 21st Annual National Neurotrauma Society Symposium, Biloxi, MS USA. Pearse DD, Pereira FC, Marcillo AE, Berrocal YA, Filbin M, Bunge MB (2003) Elevation of cyclic AMP enhances regeneration and improves behavioral recovery in Schwann cell-grafted animals after spinal cord injury. The 10th International Symposium of Neural Regeneration, Pacific Grove, CA USA.

Pearse DD, Pereira FC, Marcillo AE, Bates ML, Berrocal YA, Bunge MB (2003) Elevation of cAMP enhances regeneration and improves behavioral recovery in Schwann cell-grafted animals after spinal cord injury, The 33rd Annual Meeting for the Society of Neuroscience, New Orleans, LA USA.

Chatzipanteli K, Pearse DD, Marcillo AE, Bunge MB, Dietrich WD (2003) Antisense mediated inhibition of iNOS acutely promotes partial hindlimb recovery after spinal cord contusion, The 33rd Annual Meeting for the Society of Neuroscience, New Orleans, LA USA. Berrocal YA, Pearse DD, Andrade CM, Bunge MB, Eaton MJ (2003) Sensory evaluation of contusive spinal cord injury (SCI) as a model to evaluate regenerative therapies in the rat. The 10th International Symposium on Neural Regeneration, Pacific Grove. CA USA. Grimpe B, Horn K, Lupa M. Bunge MB, Silver J (2003) A DNA enzyme against the xt-1, the gag chain initiating enzyme, dramatically influences Schwann cells astrocyte interactions. The 33rd Annual Meeting for the Society for Neuroscience, New Orleans, LA USA. Hill CE, Moon LDF, Bunge MB, Wood PM (2003) Identification of transplanted Schwann cells and olfactory ensheathing glia using transgenic PLAP rat cells. The 33rd Annual Meeting for the Society for Neuroscience, New Orleans, LA USA. Hill CE, Moon LDF, Bunge MB, Wood PM (2003) Identification of transplanted Schwann cells and olfactory ensheathing glia using transgenic PLAP rat cells. Program No. 415.4 2003 Abstract Viewer/itinerary Planner, Washington, DC USA: Society for Neuroscience. Hill CE, Moon LDF, Bunge MB, Wood PM (2003) Use of transgenic rat cells to identify transplanted Schwann cells within the injured and intact adult rat spinal cord. 10th International Symposium on Neural Regeneration, Pacific Grove, CA USA. Pearse DD, Pereira FC, Chatzipanteli K, Dietrich WD, Bunge MB (2002) The use of antisense-mediated inhibition to delineate the role of inflammatory agents in the pathophysiology of spinal cord injury. Nature Biotechnology Winter Symposia, February 2002, Miami, FL USA.


Pearse DD, Wanner IB, Pereira FC, Puzis R, Wood PM, Bunge MB (2002) Survival, migration and axon association of Schwann cells and olfactory ensheathing glia transplanted into the contused spinal cord. Third Asia Pacific Symposium on Neural Regeneration, Perth, Australia, 2002. p. 29.

Cho YS, Pearse DD, Marcillo, AE, Bunge MB, Dietrich WD (2002) Characterisation of a rat cervical contusion injury model using spinal cord displacement as a novel representation of human spinal cord injury (SCI). J Neurotrauma 19:1334.

Pearse DD, Chatzipanteli K, Marcillo AE, Bunge MB, Dietrich WD (2002) iNOS inhibition by pharmacological or gene therapeutic means leads to reduced blood-barrier permeability and neuronal survival after spinal cord injury (SCI). J Neurotrauma 19:1389. Pearse DD, Marcillo AE, Oudega M, Bethea JR, Wood PM, Bunge MB (2002) Transplantation of Schwann cells (with or without olfactory ensheathing glia) after spinal cord injury (SCI): Can pretreatment with methylprednisolone and interleukin-10 enhance recovery? J Neurotrauma 19:1373.

Pereira FC, Pearse DD, Tresco PA, Bunge MB (2002) Enhanced regeneration into Schwann cell bridges implanted into the completely transected spinal cord following cyclic AMP injection or superfusion into the stumps is not accompanied by improved behavioral restitution. J Neurotrauma 19:1335.

Chatzipanteli K, Pearse DD, Marcillo AE, Bunge MB, Dietrich WD (2002) Comparative pharmacological and gene therapeutic inhibition of iNOS after spinal cord injury (SCI) ablates selective pathophysiological processes. Program No. 204.14. 2002 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience.

Bunge MB, Pereira FC, Pearse DD (2002) Muramyl diethyl peptide (MDP) administration protects white matter and reduces long-term functional deficits after contusive spinal cord injury (SCI). Program No. 204.12. 2002 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience.

Pearse DD, Pereira FC, Marcillo AE, Bunge MB (2002) Increased cyclic nucleotide levels and inhibition of phosphodiesterases promotes regeneration and improved behavioral recovery in Schwann cell-grafted animals after spinal cord contusion (SCI). Program No. 204.20. 2002 Abstract Viewer/Itinerary Planner. Washington, DC USA: Society for Neuroscience.

Chatzipanteli K, Pearse DD, Marcillo A, Bunge MB, Dietrich DD (2002) Inhibition of iNOS after moderate contusive spinal cord injury (SCI) pharmacologically with 1400W and INOS antisense targeting: Reduced blood-brain-barrier permeability and neuronal necrosis. The 32nd Annual Meeting for the Society for Neuroscience. Orlando, FL USA. Bunge MB, Pereira FC, Pearse DD (2002) N-Acetylmuramyl-L-Alanyl-D-Isoglutamine (MDP) administration protects white matter and reduces long-term functional deficits associated with contusive spinal cord injury (SCI). The 32nd Annual Meeting for the Society for Neuroscience, Orlando, FL USA. Pearse DD, Pereira FC, Marcillo A, Bunge MB (2002) Increased cyclic nucleotide levels and sustained inhibition of phosphodiesterase expression by rolipram to prevent its hydrolysis promotes regeneration and improved behavioral recovery in Schwann cell-grafted animals after contusive spinal cord injury. The 32nd Annual Meeting for the Society for Neuroscience, Orlando, FL USA. Pereira FC, Pearse DD, Bunge MB (2002) Cyclic nucleotide administration acutely after spinal cord injury (SCI) in combination with Schwann cell (SC) transplantation: the promotion of spasticity. Program No. 204.13. 2002 Abstract Viewer/Itinerary Planner. Washington, DC USA: Society for Neuroscience.


Pereira FC, Pearse DD, Bunge MB (2002) Cyclic nucleotide administration acutely after spinal cord injury (SCI) in combination with Schwann cell (SC) transplantation: the promotion of spasticity. The 32nd Annual Meeting for the Society for Neuroscience, Orlando, FL USA. Leasure JL, Thallmair M, Perreau V (2002) The Christopher Reeve Paralysis Foundation Research Consortium. Temporal and regional gene expression after moderate spinal cord injury in the adult rat, The 32nd Annual Meeting for the Society of Neuroscience, Orlando, USA. Ryan JC, Dragicevic N, Liebl DJ, Bixby JL, Bunge MB, Bookman RJ (2002) Spatio-temporal resolution of cell populations and gene expression following spinal cord injury in mice. Program No. 393.5. 2002 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience.

Pearse DD, Pereira FC, Chatzipanteli K, Dietrich WD, Bunge MB (2001) The use of antisense-mediated inhibition to delineate the role of inflammatory agents in the pathophysiology of spinal cord injury. Scientific World.

Pearse DD, Pereira FA, Diaz P, Castro S, Bunge MB (2001) Selective inhibition of TNF- expression after spinal cord injury (SCI) by antisense oligonucleotides (ASO) dramatically reduces astrogliosis and promotes neuronal survival. J Neurotrauma 18:1169.

Pereira FC, Pearse DD, Bunge MB (2001) Inactivation of injury-activated microglia by TNF- antisense oligonucleotides (ASO) in vitro. J Neurotrauma 18:1156.

Pearse DD, Pereira FC, Bunge MB (2001) Injection of n-acetylmuramyl-l-alanyl-d-isoglutamine (MDP) improves histological and behavioral outcome after contusive spinal cord injury (SCI). Soc Neurosci Abstr 27:2042, San Diego, CA USA. Pearse DD, Pereira FC, Bunge MB (2001) Can activation of macrophages and microglia to increase myelin digestion improve regeneration after spinal cord injury?, Functional Recovery after Spinal Cord Injury Conference, Ascona, Switzerland. Pearse DD, Pereira FC, Bunge MB (2001) Selective inhibition of TNF-α expression after spinal cord contusion by antisense oligonucleotides dramatically reduces astrogliosis and promotes neuron survival, The 19th Annual National Neurotrauma Society Symposium, San Diego, CA USA.

Bunge MB, Takami T, Wood PM, Kleitman N, Oudega M (2001) Schwann cell and olfactory ensheathing glia transplantation in the moderately contused adult rat spinal cord. Soc Neurosci Abstr 27:966.

Plant GW, Oudega M, Christensen CL, Cuervo E, Bunge MB (2001) Acute and sub-acute transplantation of olfactory ensheathing glia into the contused adult rat spinal cord. Soc Neurosci Abstr 27:1838.

Oudega M, Timmers L, Meijs MFL., Pearse DD, Bunge MB, Joosten EAJ (2001) Effects of basic fibroblast growth factor on neuronal survival, angiogenesis, and axonal regeneration in Schwann cell grafts placed in the completely transected adult rat spinal cord. Soc Neurosci Abstr 27:967, San Diego, CA USA.

Bunge MB (2000) Strategies to improve outcome after spinal cord injury. J Restor Neurol Neurosci 17(2-3). Takami T, Oudega M, Marcillo AE, Bethea JR, Bunge MB (2000) Methylpresnisolone alone and in combination with human IL-10 reduces gray matter but not white matter loss in the contused adult Fischer rat thoracic spinal cord. J Neurotrauma 17:962.


Takami T, Oudega M, Marcillo AE, Bethea JR, Bunge MB (2000) Neuroprotective effects of methylpresnisolone and human IL-10 on the contused adult Fischer rat thoracic spinal cord. Soc Neurosci Abstr 26:1103. Blits B, Oudega M, Boer GJ, Bunge MB (2000) Adenoviral vector-mediated delivery of neurotrophic factors promotes axonal growth from a Schwann cell (SC) graft into the adult rat spinal cord and improves hindlimb function. Soc Neurosci Abstr 26:1103.

Bunge MB, Takami T, Marcillo AE, Oudega M (2000) Schwann cell and ensheathing glia implantation in the contused adult rat thoracic spinal cord. Soc Neurosci Abstr 26:1103.

Oudega M, Plant GW, Bunge MB (2000) Schwann cell and olfactory ensheathing glia implantation in the contused adult rat thoracic spinal cord. Exp Neurol 163:303.

Bunge MB (1999) What combination of cells and factors will promote repair of injured adult mammalian spinal cord? Fifth IBRO World Congress of Neuroscience (invited symposium speaker).

Plant GW, Wood PM, Bunge MB (1999) P75 purified ensheathing glia from adult rats fail to myelinate rat dorsal root ganglion axons in vitro. J Neurotrauma 16:1012. Oudega M, Khalfallah M, Bates ML, Onifer SM, Yan H, Gravel C, Tadie M, Bunge MB (1999) Schwann cells secreting BDNF and NT-3 in collagen type IV guidance tubes promote axonal regeneration into the adult rat thoracic spinal cord. Exp Neurol 159:609-610.

White L, Fregien N, Olson L, Bunge MB, Wood PM (1999) Forskolin-independent expression of neuregulin receptors in human Schwann cells in vitro. Soc Neurosci Abstr 25:2044. Yan HL, Bunge MB, Plant GW (1999) Heregulin and FGF-2 stimulate proliferation of olfactory ensheathing glia from adult rat in vitro. Soc Neurosci Abstr 25:2044

Casella G, Bunge MB, Kleitman N, Marcillo A, Nagashima H, Weber A, Wood P (1999) Angiogenesis after moderate contusion of adult rat spinal cord. Soc Neurosci Abstr 25:1330.

Oudega M, Plant GW, Katz J, Marcillo A, Bunge MB (1999) Schwann cell and ensheathing glia transplantation into the contusion injured adult rat spinal cord. Soc Neurosci Abstr 25:748.

von Euler M, Janson, AM, Larsen JO, Seiger Á, Bunge MB, Sundström E (1999) Spontaneous axonal regeneration in rodent spinal cord after ischemic injury. Soc Neurosci Abstr 25:493.

Onifer SM, Loor KE, Cannon AB, Walsh JL, Santiago DI, Bunge MB (1999) Combining methylprednisolone, peripheral nerves, FGF1, fibrin, and vertebral wiring for spinal cord repair. Soc Neurosci Abstr 25:492.

Plant GW, Horner PJ, Gage FH, Bunge MB (1999) NT-3 prevents degeneration of the corticospinal tract whereas BDNF transiently induces behavioral improvement in the completely transected spinal cord. Soc Neurosci Abstr 25:211. Emery E, Aldana P, Puckett W, Srinivasan A, Keane RW, Bethea J, Bunge MB, Levi A (1998) Apoptosis after traumatic human spinal cord injury. Soc Neurosci Abstr 24:1554. Plant GW, Dimitropolou A, Bates ML, Bunge MB (1998) The expression of inhibitory proteoglycans following transplantation of Schwann cell grafts into completely transected adult rat spinal cord. Soc Neurosci Abstr 24:69.

Ramón-Cueto A, Plant GW, Avila J, Bunge MB (1998) Promotion of long distance axonal regeneration in the transected adult rat spinal cord by olfactory ensheathing glia transplants. Europ J Neurosci 10:57.


Oudega M, Vargas C, Weber A, Kleitman N, Bunge MB (1997) Effects of methylprednisolone (MP) on axonal growth and die back in the transected thoracic adult rat spinal cord. Soc Neurosci Abstr 23:1726.

Onifer SM, Grover VP, Vargas CG, White LA, Gomez AM, Bunge MB, Bunge RP (1997) Schwann cell, carbon filament, and collagen grafts placed in the adult rat cervical spinal cord to promote chronically injured axon regeneration. Soc Neurosci Abstr 23:1727.

Guest JD, Kleitman N, Aebischer P, Bunge MB, Bunge RP (1996) Axonal regeneration into human Schwann cell grafts placed to span the transected spinal cord of the nude rat. Soc Neurosci Abstr 22:1231.

Oudega M, Fernandez-Valle C, Wood P, Gomez A, Weber A, Bates M, Bunge MB (1996) Schwann cells cultured in serum-free (7F) medium: myelination studies in vitro and in vivo. Soc Neurosci Abstr 22:1229.

Broton JG, Xu XM, Bunge MB, Lutton S, Cuthbert T, Calancie B (1996) Hindlimb movements of adult rats with transected spinal cords. Soc Neurosci Abstr 22:1096. Onifer SM, Cannon AB, White LA, Bunge MB, Bunge RP, Whittemore SR (1996) Transplantation strategies to replace degenerated spinal motoneurons and reinnervate muscle. Soc Neurosci Abstr 22:1021

Menei P, Montero-Menei C, Whittemore SR, Bunge MB, Bunge RP (1996) Schwann cells genetically engineered to produce BDNF promote axonal regeneration of brainstem neurons across transected adult rat spinal cord. Soc Neurosci Abstr 22:1022.

Dancausse HA, Brunschwig JP, Bunge MB, Yezierski RP (1995) Morphological characterization of excitotoxic injury in the rat spinal cord. Soc Neurosci Abstr 21:231. Xu XM, Guénard V, Kabeer NH, Bates M, Bunge MB (1995) Cellular transplantation into a partial lesion model to stud axonal regrowth in the adult rat spinal cord. Soc Neurosci Abstr 21:820. Oudega M, Xu XM, Guénard V, Kleitman N, Wells M, Bunge MB (1995) Effects of platelet-derived growth factor and insulin-like growth factor-I on axonal regeneration in the adult rat spinal cord. Soc Neurosci Abstr 21:314.

Chen A, Xu X-M, Kleitman N, Bunge MB (1994) The efficacy of Schwann cell seeded guidance channels in promoting axonal regeneration in adult rat spinal cord is enhanced by methylprednisolone. 5th International Symposium on Neural Transplantation, June 25-29, Chatenay-Malabry, France.

Bunge MB (1994) Transplantation of purified populations of Schwann cells (SCs) into lesioned adult rat spinal cord. J Neurol 241:S36-S39.

Bunge MB (1994) Nerve regeneration studies. The Aluminum Association Proceedings.

Broton JG, Xu X-M, Bunge MB, Calancie B (1994) Kinematic and EMG analyses of control and spinal cord transected rats during treadmill locomotion. Soc Neurosci Abstr 20:1705.

Chen A, Xu XM, Kleitman N, Bunge MB (1994) Methylprednisolone administration improves axonal regeneration into Schwann cell (SC) grafts in thoracic rat spinal cord. Soc Neurosci Abstr 20:1111.

Xu X-M, Guénard V, Kleitman N, Bunge MB (1994) BDNF and NT-3 promote supraspinal axonal regeneration into a Schwann cell graft in adult rat thoracic spinal cord. Soc Neurosci Abstr 20:1111.

Xu X-M, Guénard V, Chen A, Kleitman N, Bunge MB (1993) Rostral and caudal axonal regeneration into Schwann cell-seeded guidance channels grafted into a gap in adult rat spinal cord. Soc Neurosci Abstr 19:681.


Fernandez-Valle L, Gwynn P, Wood S, Carbonetto, Bunge MB (1993) Antibodies to the ß1 integrin subunit inhibit Schwann cell myelination. Molec Biol Cell 4:283a.

Fernandez-Valle C, Gwynn L, Wood P, Carbonetto S, Bunge MB (1993) Antibodies to the ß1 integrin subunit inhibit Schwann cell myelination. Am Soc Cell Biology.

Bunge RP, Bunge MB (1993) Prospects for treatment of chronic human neural injury. J Neurotrauma Abstr 10(Suppl.1):S123.

Bunge MB, Xu X-M, Guénard V, Kleitman N (1993) Transplantation of cultured Schwann cells into adult rat spinal cord. Gene Transfer Strategies in the Study of Brain Damage and Repair meeting, June 2-5, Stockholm, Sweden.

Xu XM, Guénard V, Chen A, Kleitman N, Bunge MB (1993) Axonal regeneration of ascending and descending adult rat spinal cord neurons after transection and grafting of SC-seeded guidance channels. 11th Annual Neurotrauma Symposium, November 5-6, Washington, DC.

Xu X-M, Guénard V, Chen A, Kleitman N, Bunge MB (1993) CNS axons regenerate rostrally and caudally through Schwann cell-seeded guidance channels grafted to a gap in the adult rat spinal cord. Fifth International Regeneration Symposium, December 8-12, Pacific Grove, CA, p. 68.

Bunge MB, Paino C, Fernandez-Valle C (1992) Implantation of cultured Schwann cells to foster repair in damaged mammalian spinal cord. J Cell Biochem Suppl 16F:125.

Xu X-M, Guénard V, Kleitman N, Bunge MB (1992) Axonal growth into Schwann cell-seeded guidance channels grafted into transected adult rat spinal cord. Soc Neurosci Abstr 18:1479.

Fernandez-Valle C, Wood PM, Bunge MB (1991) Schwann cells fail to remyelinate axons following injury in culture in differentiation supporting medium. Soc Neurosci Abstr 17:202.

Obremski VJ, Bunge MB (1991) Exogenous purified basal lamina components cause abnormal Schwann cell ensheathment of sympathetic neurites in culture. Soc Neurosci Abstr 17:203.

Paino CL, Fernandez-Valle C, Bunge MB (1991) Axon growth into Schwann cell grafts placed in lesioned adult rat spinal cord. Soc Neurosci Abstr 17:236.

Obremski VJ, Bunge MB (1990) Exogenous basal lamina matrix increases Schwann cell ensheathment of sympathetic neurites in vitro. J Cell Biol 111:268a.

Paino CL, Bunge MB (1990) Axon growth into implants of Schwann cells placed in lesioned spinal cord. Soc Neurosci Abstr 16:1282.

Salvatierra AT, Holets VR, Bunge MB (1990) Characterization of rat spinal cord changes following photochemically-induced injury. Soc Neurosci Abstr 16:1282.

Ard MD, Bunge MB (1989) Astrocytes matured in vitro support retinal neurite outgrowth. Soc Neurosci Abstr 15:878.

Bunge MB, Wood PM (1989) Basal lamina deposition on Schwann cells cultured with fibroblasts in the absence of neurons. Soc Neurosci Abstr 15:689.


Holets VR, Salvatierra A, Prado R, Bunge MB, Bunge RP, Watson BS (1989) A photochemically-induced spinal cord injury model. Soc Neurosci Abstr 15:129.

Obremski VJ, Bunge MB (1989) Diffusible substances from fibroblasts cause assembly of basal lamina on Schwann cells. J Cell Biol 109:238a.

Gorman DS, Bunge MB (1988) Myelination of axons by Schwann cells is f-actin dependent, as determined by the use of cytochalasin. Soc Neurosci Abstr 14:425.

Obremski VJ, Johnson MI, Bunge MB (1988) Schwann cell basal lamina formation and ensheathment of unmyelinated neurites are increased in cultures containing fibroblasts. Soc Neurosci Abstr 14:426.

Gorman DS, Bunge MB (1988) Functional actin is required for myelination of axons by Schwann cells. J Cell Biol 107:515a. Bunge RP, Bunge MB, Owens GC (1988) Cellular mechanisms involved in peripheral myelin sheath formation. J Cell Biol 107:666a.

Eldridge CF, Bunge MB, Bunge RP (1987) The role of basal lamina in Schwann cell function. Anat Rec 218:40a. Eldridge CF, Bunge RP, Bunge MB (1987) Control of Schwann cell myelin formation by basal lamina. Soc Neurosci Abstr 13:889.

Kuhlengel KR, Bunge RP, Burton H, Bunge MB (1987) Effect of dorsal root ganglion neuron plus Schwann cell implants on growth of corticospinal fibers after spinal cord injury in neonatal rats. Soc Neurosci Abstr 13:397.

Bunge MB, Sanes JR, Wood PM, Tynan LB, Bates ML (1987) The cellular source of perineurium determined with a retroviral marker. Soc Neurosci Abstr 13:183.

Kuhlengel KR, Bunge RP, Burton H, Bunge MB (1987) Effect of dorsal root ganglion neuron plus Schwann cell implants on growth of corticospinal fibers after spinal cord injury in neonatal rats. In: Abstracts, Transplantation into the Mammalian CNS, p. 35.

Bunge MB (1987) Linkage between Schwann cell ensheathment function and extracellular matrix production. Muscle & Nerve 9(supplement 55):59.

Bunge RP, Bunge MB, Bates M, Bray D (1986) Evidence that the myelin spiral is formed by progression of the inner Schwann cell lip around the axon. Soc Neurosci Abstr 12:395.

Ard MD, Bunge RP, Bunge MB (1985) Role of Schwann cells and their extracellular matrix in promoting neurite growth in vitro. Soc Neurosci Abstr 11:761.

Clark MB, Eldridge CF, Bunge MB (1985) Neuronal regulation of basal lamina formation by Schwann cells. Soc Neurosci Abstr 11:986.

Eldridge CF, Bunge MB, Bunge RP (1985) Serum ascorbic acid regulates myelin formation and basal lamina assembly by Schwann cells in vitro. Soc Neurosci Abstr 11:986.

Eldridge CF, Bunge MB, Bunge RP (1984) The effects of ascorbic acid on Schwann cell basal lamina assembly and myelination. J Cell Biol 99:404a.

Argiro V, Bunge MB, Johnson MI (1983) Predominance of filopodia or lamellipodia is correlated with rate of growth cone translocation. J Cell Biol 97:248a.


Eldridge CF, Bunge MB, Bunge RP (1983) Biochemical effects of cis-4-hydroxy-L-proline on Schwann cells differentiating in vitro. J Cell Biol 97:244a.

Williams AK, Bunge MB, Wood PM, Argiro V (1983) Differences in collagen fibrils formed by fibroblasts (Fbs) from different sources with or without neurons (NCs) and Schwann cells (SCs). J Cell Biol 97:89a.

Roufa D, Cornbrooks C, Johnson M, Bunge MB (1982) Preparation of homogenous populations of immature Schwann cells from early embryonic sympathetic ganglia. Soc Neurosci Abstr 8:240.

Williams AK, Bunge MB, and Wood PM (1982) The development of perineurium in culture. J. Cell Biol. 95:2a.

Cochran M, Bunge MB (1981) Reduction of growth cone vesicle-filled mounds following fixation in glutaraldehyde-osmium mixtures. Anat Rec 199:55A.

Argiro V, Bunge MB, Johnson M (1981) Quantitative time-lapse analysis of growth cone motility of cultured rat autonomic neurons. J Cell Biol 91:92a.

Roufa D, Johnson M, Bunge MB (1981) Differences in neuritic growth pattern depending upon neuritic age and culture substrata. J Cell Biol 91:91a. Moya F, Bunge RP, Bunge MB (1980) Development of dorsal root ganglia cultures in a defined medium. In Vitro 16:250. Cornbrooks C, Cochran M, Mithen F, Bunge MB, Bunge R (1980) Myelination in explants of trembler dorsal root ganglion grown in culture. Trans Am Soc Neurochem 11:110. Copio DS, Bunge MB (1980) Use of a proline analog to disrupt collagen synthesis prevents normal Schwann cell differentiation. J Cell Biol 87:114a. Bunge MB, Williams AK, Wood PM (1979) Further evidence that neurons are required for the formation of basal lamina around Schwann cells. J Cell Biol 83:130a.

Cochran M, Bunge RP, Bunge MB (1978) Requirement of additional factor(s) for normal interaction between Schwann cells and nerve fibers. Soc Neurosci Abstr 4:109.

Bunge RP, Bunge MB, Okada E, Wood P (1978) Myelination of sensory ganglion neurites by oligodendrocytes. J Neuropath Exp Neurol 37:596.

Bunge MB, Jeffrey J, Wood P (1977) Different contributions of Schwann cells and fibroblasts to the collagenous components of peripheral nerve. J Cell Biol 75:161a.

Williams AK, Wood P, Bunge MB (1976) Evidence that the presence of Schwann cell basal lamina depends upon interaction with neurons. J Cell Biol 70:138a.

Rees RP, Bunge MB (1975) Origin of coated vesicles in neuronal perikarya - a study of peroxidase uptake by cultured neurons with or without neurites. J Cell Biol 67:357a. Pfenninger KH, Bunge MB, Bunge RP (1974) Nerve growth cone plasmalemma - its structure and development. In: Abstracts of the Eighth International Congress on Electron Microscopy, JV Sanders, DJ Goodchild, (eds), Vol. 2, Australian Academy of Science, Canberra, pp. 234-235.

Yu R, Bunge MB (1974) Rapid repair of abnormalities in the myelin sheath induced by glycerol treatment of cultured spinal ganglia. In: Program and Abstracts of the Society for Neuroscience, 4th Annual Meeting, p. 493.


Bunge MB (1973) Uptake of peroxidase by growth cones of cultured neurons. Anat Rec 175:280.

Pfenninger KH, Bunge MB (1973) Observations on plasmalemmal growth zones in developing neural tissue. J Cell Biol 59:264a.

Bunge MB, Bray D (1970) Fine structure of growth cones from cultured sympathetic neurons. J Cell Biol 47: (part 2) 241a.

Bunge RP, Bunge MB (1969) A comparison of neuronal changes following colchicine treatment with observations on other conditions involving the accumulation of neurofilaments. J Neuropath Exper Neurol 28:169.

Bunge R, Bunge MB (1968) Electron microscopic observations on colchicine induced changes in neuronal cytoplasm. Anat Rec 160:323. Brosnan CF, Bunge MB, Murray MR (1968) The formation of acid phosphatase-positive, multilamellated bodies in cultured neurons exposed to chlorpromazine. J Cell Biol 39:17-18A.

Masurovsky EB, Bunge MB, Bunge RP (1966) Electron microscopic study of the effects of X-irradiation on organotypic cultures of rat dorsal root ganglia. Abstr Third Int Cong Radiation Res., Cortina D'Ampezzo, Italy, p.150.

Masurovsky E, Bunge MB (1966) Consequences of satellite cell loss from neuron in X-irradiated cultures of rat dorsal root ganglia. Anat Rec 154:474. Hendelman WJ, Bunge MB (1966) Some observations on the disposition of microtubules in relation to the myelin sheath. J Cell Biol 31:46A-47A.

Bunge RP, Bunge MB (1966) An evaluation of some determinants of neuronal size and internode length in peripheral nerve. Anat Rec 154:324.

Bunge MB, Bunge RP, Crain SM, Peterson ER, Murray MR (1965) Electron microscopic and bioelectric observations on cultured spinal cord during the development of synaptic networks. Abstr 8th Int Cong Anat, Wiesbaden, Germany, p.21.

Bunge RP, Bunge MB (1965) Ultrastructural characteristics of synapses forming in cultured spinal cord. Anat Rec 151:329. Bunge MB, Bunge RP, Peterson ER, Murray MR (1964) Comparative light and electron microscope studies of chlorpromazine-treated neurons. Excerpta Medica, Section I, 18: (No. 1), IX.

Crain SM, Bunge RP, Bunge MB, Peterson ER (1964) Bioelectric and electron microscopic evidence for development of synapses in spinal cord cultures. J Cell Biol 23:114A-115A.

Bunge RP, Bunge MB (1964) Electron microscopic observations on glial cells in tissue culture. Anat Rec 148:266.

Bunge R, Bunge MB, Peterson E, Murray M (1963) Ultrastructural similarities between in vitro and in vivo central nervous tissue. J Cell Biol 19:11A.

Bunge RP, Bunge MB (1963) Electron microscopic autoradiographic studies of amino acid incorporation into cultured dorsal root ganglion neurons. Anat Rec 145:213.


Bunge R, Bunge MB, Peterson E (1962) Electron microscopic observations on cultured dorsal root ganglia, Abstracts of the 2nd Annual Meeting of the American Society for Cell Biology, San Francisco, 28.

Koenig H, Bunge RP, Bunge MB (1961) An autoradiographic study of nucleoprotein metabolism during demyelination and remyelination in spinal cord of adult cats. J Neuropath Exper Neurol 20:279.

Bunge MB, Bunge RP (1961) Myelin sheath-glial cell relationships in myelinating mammalian central nervous tissue. Abstracts of the 1st Annual Meeting of the American Society for Cell Biology, Chicago, 25.

Bunge MB, Bunge RP (1960) Electron microscopic study of demyelination and remyelination in an experimentally induced lesion in adult cat spinal cord. Anat Rec 136:332-333.

Bunge MB (1960)Ultrastructural study of myelin breakdown and reformation in an experimentally induced lesion in adult cat spinal cord. Dissertation Abstracts 21:705.

Schilling RF, Bunge MB, Schloesser LL (1956) Preferential binding and absorption of cyanocobalamin in the presence of excess pseudovitamin B12. J Lab and Clin Med 48:939.

20. Other works in print

Magazines: 8/2010 Personal story featured in Christopher and Dana Reeve Foundation Progress in Research

Newsletter 5/2006 University of Miami Veritas article, “The Miami Project enters a new era” Announces the Miami

Project clinical trials initiative to move forward the combination therapy developed by Drs. Pearse and Bunge to human SCI

1/2005 University Journal article, “Striking a Nerve” Describes a major SCI breakthrough by Drs. Pearse and Bunge

6/2004 University of Miami Veritas article, “A research breakthrough” describes a major SCI breakthrough by Drs. Pearse and Bunge

6/2004 School of Medicine SCRIP article, “Animals walk near normal in research breakthrough” describes a major SCI breakthrough by Drs. Pearse and Bunge

5/2004 University of Miami Veritas article, “A major ‘step’ forward in curing paralysis” describes a major SCI breakthrough by Drs. Pearse and Bunge 5/2004 Forbes Magazine article, “Combination Therapy Overcomes Spinal Injuries in Rats”

Columnist: Amanda Gardner, discussions of major SCI breakthrough by Drs. Pearse and Bunge 2001 Article on mentoring, University of Miami, Miami Medicine 2001 Featured in May issue of Veritas, University of Miami

2001 Featured in chapter of book entitled:”In Search of the Lost Cord: Solving the Mystery of Spinal Cord Regeneration” by Luba Vikhanski, The Dana Press

Newspapers: 5/2004 USA Today (front page) “Treatment combination helps paralyzed rats walk: Spinal cord advances

called “significant” Columnist: Anita Manning Radio Interviews/Addresses: 6/2004 ABC Radio Australia Interview with Dr. Pearse, “Spinal cord treatment breakthrough”

Reporter: Michael Vincent, discussions of major SCI breakthrough by Drs. Pearse and Bunge 5/2004 National Public Radio Interview with Dr. Pearse, All Things Considered, “Miami Spinal

Therapy”


Reporter: Robert Siegel, discussions of major SCI breakthrough by Drs. Pearse and Bunge

Television Specials: 5/24/2004 CNN News Health, “Paralysis study shows promise” 5/23/2004 CBS News SciTech, “Rats regrow damaged nerves”

PROFESSIONAL 21. Funded Research Performed: Selected Funded Grants

R01 NS09923-40-45 A1, NIH/NINDS, 8th percentile. Cytological Studies of Developing and Mature Neurons (old title for continuity). The goal is to find more effective combination strategies with Schwann cell (SC) transplantation to improve spinal cord repair with emphasis on modifying SC implant/host spinal cord interfaces. Co-Principal Investigators, Mary B. Bunge and John Bethea.

R01 NS09923, NIH/NINDS, 5th percentile. Cytological Studies of Developing and Mature Neurons. The goal is to better understand the role of cyclic AMP in rat and human Schwann cell proliferation and myelination in vitro and in vivo. Principal Investigator Mary B. Bunge. 03/01/05-02/28/12. Earlier this grant funded a new electron microscope. Now in its 39th year (2010). R01 NS056281-01A1, 10th percentile. Axon Regeneration: Synergistic Actions of the MAPK and Cyclic AMP Pathways. The goal is to better understand the mechanisms underlying an improved repair response with cAMP after spinal cord injury. Principal Investigator: Damien Pearse; Co-Investigator, Mary B. Bunge. 06/01/07-05/31/12.

DAMD W 81 XWH-10-1. Schwann cell (SC) implantation for SCI Repair: Optimization. The goal is to examine migration, toxicity, cell dose and tumor formation for up to 6 mo. for FDA final approval for our proposed SC clinical trial. Principal Investigator: Damien D. Pearse; Partnering Investigator: Mary B Bunge. 09/01/10-10/31/13 Dr. Barth A. Green’s Christine E. Lynn Distinguished Chair in Neuroscience. Bunge (PI). 2003 until I stop working. This funding helps to support a number of projects in the Bunge laboratory including those that are developed to generate national funding after preliminary work. Role: P.I.

Ralph C. Wilson Medical Research Foundation. Development of Improved Conduits to Introduce Cells, Growth Factors and Extracellular Matrices into the Injured Rat Spinal Cord for Effective Repair. The goal of this project is to find an effective scaffold to transplant Schwann cells into injured adult rat spinal cord and to use that scaffold to release growth factor. Principal Investigator: Mary B. Bunge. 01/01/08-11/30/10. Christopher and Dana Reeve Foundation/International Research Consortium, Principal Investigator: Mary B. Bunge. Entitled “Studies of Schwann Cell Transplantation.” Funding from 1995-2011, with renewals every 2-3 years. $260,000/year. University of Florida. Transplantation of Adult Neural Progenitors (AHNPS) into the Contused Adult Rat Spinal Cord. The aim of this project is to assess survival and differentiation of AHNPs transplanted into the immune suppressed adult rat spinal cord that has received a contusion spinal cord injury. Principal Investigator: Mary B. Bunge. 10/01/08-5/30/10. NINDS Contracts, N01 NS32351 and N01 NS32352, to establish a Facility of Research Excellence in Spinal Cord Injury at the Miami Project to Cure Paralysis for training and replication studies, respectively. W. Dalton Dietrich, Director; Mary B. Bunge, Co-director. 02/01/03-01/31/08. $1,556,497 and $1,047,180 respectively.


Principal Investigator Dr. Mary B. Bunge with Dr. Patrick Wood, continuation of R01 NS09923-28 to 33. Because of 0.8 percentile score, received a third Javits Award for the grant; Entitled “Cytological Studies of Developing and Mature Neurons” Periods: 09/01/98-08/31/05 - $1,334,186; Infrastructure Supplement Award on NS09923. 06/01/99 - $25,000.

Program Project Grant1P01NS38665-01A2. Principal Investigators Project 2: Mary B. Bunge, Patrick M. Wood, Naomi Kleitman, Martin Oudega. Principal Investigator Core C: Mary B. Bunge. Entitled “Combination Strategies to Improve Outcome after Contusion Injury”. Project 2: 07/01/00–06/30/05 - $761,525; Core C: 07/01/00-06/30/05 - $491,895.

International Spinal Research Trust. Research Grant. Principal Investigators, Patrick M. Wood, Ph.D., Mary B. Bunge, Ph.D., Naomi Kleitman, Ph.D. Entitled “Generation and Testing of Rat and Human Ensheathing Glia for Spinal Cord Transplantation”. Period: 06/01/00-05/31/03 - $278,783. (Also, 09/1997-08/31/00; Studies of Gene Expression in Human Schwann cells)

Co-investigator with Dr. Richard P. Bunge on a grant given a Jacob Javits Award (for years 16-22, 1986-1993, USPHS-NIH/NINDS NS09923-25) entitled “Cytological Studies of Developing and Mature Neurons”. Renewed in 1993 (2.9 percentile) and given a second Javits Award, 07/01/93-06/03/2000; in 1996, M.B. Bunge became PI on the grant.

Investigator in Program Project Grant entitled “Study of Cellular Therapy in Chronic Spinal Cord Injury”, NINDS 1 PO1 NS28059-01A1, 1/1/91-12/31/95.

Principal Investigator, Mary Bartlett Bunge, NINDS 1 PO1 NS28059-01A1 Supplement (Richard P. Bunge, P.I.) Core B: Histology/Electron Microscopy. Request for one-time expenditure for purchase of new electron microscope; percentile, 2.7. Funded January, 1992. Co-PI with Dr. Paul Bridgman for NIH DRR-BRS Shared Instrument Grant, “High Performance Electron Microscope for Biomedical Research”, for the purchase of a JEOL JEM-1200EX Electron Microscope (1987-1988).

Program Project Grant NS15070 entitled “Regeneration and Functional Recovery in Neural Tissue”. Own research component plus seven others plus three core units; served as Program Director of the entire grant from 1979-1989.

22. Editorial responsibilities: Editorial Boards Experimental Neurology, 1997-2012

Journal of Neurocytology, 1980-1983; 1991-2010 Journal of Cell Biology, 1980-1983

Also, reviewer for:

Journal of Cell Biology, Journal of Neuroscience, Journal of Histochemistry & Cytochemistry, Neuron, Brain Research, Experimental Neurology, Journal of Comparative Neurology, Science, Nature, Journal of Neurotrauma, Proc. Nat’l Academy of Sciences, Nature Medicine, European Journal of Neuroscience, Annals of Neurology, Journal of Neuropathology and Experimental Neurology.

23. Professional and Honorary Organizations: National Academy of Medicine American Society of Transplantation Society for Neuroscience

The American Society for Cell Biology

Curriculum Vitae BUNGE, Mary Bartlett, Ph.D. Page -31- National Neurotrauma Society AAAS American Society for Neural Transplantation and Repair American Society for Gene Therapy Women in Neuroscience Women in Neurotrauma Research

Society and Board Activities

SFN, Panel; Dialogue between Neuroscience and Society (Chuck Close, American artist), 2012 SFN, Neurobiol of Disease workshop speaker: Axon regeneration, 2008

Member, Christopher and Dana Reeve Foundation International Research Consortium, 1995-2009 Member, Public Education and Communication Committee, Society for Neuroscience, 2007-2010

(Co-chair, National Health Museum sub-committee) Member, Neural Disorders Gene Therapy Committee, American Society of Gene Therapy, 2007-2010 Member, Scientific Advisory Board, Brain Research Institute, University of Florida, 2006-2010 Member, Comm to decide on recipient of Reeve/Irvine spinal cord injury research medal, 2005-present Member, Institute of Medicine’s Committee on Spinal Cord Injury, 2003-2005 A book entitled, Spinal Cord Injury: Progress, Promise and Priorities (2005)

Member, External Advisory Panel, ICORD Spinal Repair Center, University of British Columbia, Vancouver, 2003-06

Member, Scientific Advisory Board, Facility of Research Excellence in Spinal Cord Injury at the Reeve-Irvine Center, University of California, 2003-2009

Member, Committee to choose abstracts for 2003 National Neurotrauma Meeting Member, History of Neuroscience Committee, Society for Neuroscience, 2002-2005 Abstract Review Committee for the 1st Joint Symposium of the National and Int’l Neurotrauma Societies

Member, Program Committee for the First Joint meeting of the National Neurotrauma Society (20th) and the International Neurotrauma Society (6th), Saddlebrook Resort, FL, 2002

Member, Program Committee for the 19th annual Nat’l Neurotrauma Society Symp, San Diego, 2001 Member, Scientific Advisory Board, COBRE NIH grant, University of Louisville School of Medicine,

2001-2009. Met once a year. Chair in 2007, 2008, 2009 Member, Comm to choose 2001 recipient of the Mika Salpeter WIN Lifetime Achievement Award, 2001

Member, NIH Search Committee to recommend new Director of NINDS, 2001-2003 Member, Dana Alliance for Brain Initiatives, 1999-present Advisor, Repair and Plasticity group, NINDS, 1999-2001

Member, VA Office of Regeneration Research Programs Advisory Board (to plan Asilomar meetings), 1998-2001

Member, Wakeman Award Committee, 1998-2000 Member, International Spinal Research Trust Network 1998-present Member, Committee to choose Ameritec Prize, 1997-2004

Member, External Advisory Board, Institute of Neurobiology, University of Puerto Rico, 1992-1999 Member, Membership Committee, Society for Neuroscience, 1995-1998 Member, Scientific Advisory Board, Acorda Therapeutics, Inc. 1995-2009 Member, Local Arrangements Committee for the American Society for Cell Biology, 1987 Member, Scientific Advisory Board, British Neurological Research Trust, London; 1988-1990 Member, Committee to select recipient for Ralph W. Gerard Prize, Society for Neuroscience, 1990 Member, Jury-recipient of the Fidia Research Foundation/NINDS award for brain injury research, 1991 Member, National Panel for The Decade of the Brain Implementation Plan. Created updated brochure to

be presented to Congress through the NINDS Council Member, National Task Force on NIH Strategic Plan, convened by Dr. Bernardine Healy Chair, Development of Women's Careers in Neuroscience Committee, Society for Neuroscience, 1993-

2007 (Ad hoc to Standing Committee, 1998) (Have organized three mentoring luncheons for annual meeting)


Nominated successfully Ph.D. mentor, Dr. Hans Ris, to receive the E.B. Wilson Award given by The American Society for Cell Biology, 1993

Member, Finance Committee, Society for Neuroscience, 1986-1988 Nominating Committee, American Association of Anatomists, 1982

Secretary (1963-1964) and Director (1967-1970), New York Society of Electron Microscopists 24. Honors and Awards:

Health Care Hero, Greater Miami Chamber of Commerce, 2014 Member, National Academy of Medicine, 2013 Distinguished Faculty Scholar Award, University of Miami, 2012 2008-2010 not yet entered (Symposium, distinguished lectures)

Symposium speaker, Society for Neuroscience, 2007 Donald Munro Memorial Lecture, American Paraplegia Society, 2007 Honorary doctoral degree:Doctor of Humane Science, honoris causa, Simmons College,

Boston, MA, 2006 Distinguished Visiting Scholar, Medical College of Virginia, 2006 Symposium speaker, Dept of Neuroscience, Ohio State University, 2006 Iron Arrow Honor Society (highest honor attained at UM), 2005 Lois Pope LIFE International Research Award, 2005 Provost’s Award for Scholarly Activity, 2004 Institute of Medicine Comm. (NAS) on Spinal Cord Injury, 2003-2005 Christine E. Lynn Distinguished Professorship in Neuroscience, 2003-

Symposium speaker at the Annual National Neurotrauma Society Meeting (Washington D.C.) and at the Kentucky Spine and Head Injury Research Trust, Louisville, KY, both in 2005

Thomas G. Muldoon Memorial Lecture, Medical College of Georgia, 2004 Keynote Speaker, 8th Annual Neuroscience Symposium, University of Texas, Austin, 2003

Inaugural Rick Hansen Lecturer, ICORD Spinal Repair Center, University of British Columbia, Vancouver, 2003

Lecturer for Zu Rhein Lectureship in Neuropathology, University of Wisconsin, Madison, 2003 Lecturer, Annual Neuroscience Lecture chosen by students, Emory University, Atlanta, 2003 History of Neuroscience Committee, SFN 2002-2005

Florida Woman of Achievement, 2002 Christopher Reeve Research Medal for Spinal Cord Repair, 2001

Grand Marshal, President Shalala’s inauguration, 2001 Vice-President, National Neurotrauma Society, 2001-02 Grand Marshal, UM Commencement, 2001 1/100 Most Influential Women in Florida, Miami Metro Magazine, 2001

First recipient of Mika Salpeter Women in Neuroscience Lifetime Achievement Award, 2000 Lecturer in Stanford University Symposium, Pioneering Efforts of Women in Medicine and Medical

Sciences, 2000 Raine Distinguished Visitor’s Award, University of Western Australia, 1999

Outstanding Contributions to Neuronal Regeneration Award, Oklahoma Health Sciences Center, 1999 Dean’s Senior Faculty Laboratory Research Award, 1999 Javits Neuroscience Investigator Award, 1998-2005 Mildred Trotter Lectureship (Washington University School of Medicine), 1997 First Richard P. Bunge Memorial Lecturer (Peripheral Nerve Society), 1997 The Wakeman Award, 1996 Grass Traveling Scientist, 1996 Member, Christopher and Dana Reeve Foundation International Research Consortium, 1995-2009

Curriculum Vitae BUNGE, Mary Bartlett, Ph.D. Page -33- 25. Postdoctoral Fellowships:

Postdoctoral Fellow (NINDB), 1960-1962, Department of Anatomy (Dr. George D. Pappas) and Laboratory for Cell Physiology (Dr. Margaret R. Murray), Columbia University College of Physicians and Surgeons.

26. Other Professional Activities: Visiting Professorships

1984 (July-Dec) MRC Cell Biophysics Unit, King’s College, London

Clinical Trials Involvement: 2010 Pre-IND for the Phase I clinical trial “Use of Autologous Schwann Cell Transplantation for the

treatment of Spinal Cord Injury”. 2008 Pre-pre-IND for the Phase I clinical trial “Use of Autologous Schwann Cell Transplantation for

the treatment of Spinal Cord Injury”. 2012 Successful IND application approval for this clinical trial. Patient transplantation initiated in

early December.

Scientific Presentations and Invited Lectures Keynote Speaker, 19th Annual Kentucky Spinal Cord & Head Injury Research Trust Symposium,

May (2013) Speaker, FIU, Annual Symposium, March (2012)

University of Miami Distinguished Faculty Scholar Award talk, April (2012) Speaker, University of California/Irvine Symposium to honor new Reeve medalists, May (2012)

Over many years, numerous presentations per year (both national and international) at scientific meetings, symposia, extramural seminars (including endowed lectureships), Gordon Conferences, etc. This continues to the present. Some endowed lectures are listed under “Honors and Awards”.

Symposium speaker, Reeve-Irvine Spinal Cord Center (2007). Special symposium to announce two new medalists for the Reeve-Irvine spinal cord prize.

Symposium speaker, Spinal Cord Meeting, Madison, WI (2007) Seminar speaker, Yale University, Dept. of Bioengineering (2007) Symposium speaker, combined CDRF, ISRT and Internat. Paraplegia Soc., Zurich (2007) Talk at BioFlorida meeting, Weston, FL (2007) Years 04-06 are not included. In 2003, for example, the following presentations were made:

1/03 Lecture to medical students on spinal cord injury, Neurobehavior Module (UM) 3/03 Keynote lecture, 8th Annual Neuroscience Symposium sponsored by the Institute for

Neuroscience, University of Texas, Austin 4/03 Lecture, Precourse for the American Spinal Injury Association Meeting, Miami 4/03 Lecture, Development and Regeneration of the Nervous System course (UM) 4/03 Annual Frontiers in Neuroscience Lecture, organized by students, Emory University, Atlanta 7/03 Presentation in Summer Scholars course (UM)

7/03 Distinguished Lecture in Spinal Cord Injury Techniques course at the Reeve-Irvine Research Center, California

9/03 Inaugural Rick Hansen Lecture, ICORD Spinal Cord Research Center, Univ of British Columbia 9/03 Speaker, Christopher Reeve Paralysis Foundation Consortium meeting, New York

10/03 Speaker, 4th Annual Neuroscience Graduate Program Retreat (UM) 10/03 Lecture, the Zu Rhein Lectureship in Neuropathology at the University of Wisconsin, Madison 11/03 Lecture, the National Multiple Sclerosis Society’s National Conference 12/03 Keynote speaker, ASILOMAR 10th International Symposium on Neural Regeneration


5/04 Lecture, Thomas C. Muldoon Memorial Lecture at the Medical College of Georgia Study Section and Council Memberships

Ad hoc member, Bioengineering special study section, 2007 Ad hoc member, CDRF study section, 2007

Chair, NIH Special Emphasis Panel ZRG1 VISB 01M, 2000 Ad hoc member, Study Section, NINDS-A, 1999 Member, Neurodevelopment, Plasticity and Repair Planning Group convened by Dr. G. Fischbach, Head,

National Institute of Neurological Disorders and Stroke, 1998 Member, Training Grant and Career Development (NST) Review Committee (NINDS), 1994-1995 Member, Research Advisory Board, National Neurofibromatosis Foundation, 1994-present Member, Scientific Review Panel, National Multiple Sclerosis Society (grant review), 1991-1995 Member, Howard Hughes Medical Institute Fellowship Review Panel, 1991-1993 Represented NINDS Council at 61st Meeting of Advisory Committee to the Director, NIH, 1990 Member, Nat’l Advisory Neurological and Communicative Disorders & Stroke Council, NIH, 1987-1991 Member, Neurological Disorders Program Project Review B Committee, National Institute of

Neurological and Communicative Disorders and Stroke, NIH, 1983-1987 Member of Council, American Society for Cell Biology, 1981-1983

Member, Ad Hoc NIH Study Section, to decide on a Training Program Grant from the National Institute for Aging, 1981

Recent grant reviewing Craig Neilsen Foundation N.J. Commission on Spinal Cord Injury Wings for Life A variety of other funding sources from time to time TEACHING 27. Teaching Awards Received: None 28. Teaching Specialization (courses taught):

Major teaching commitment at UMSM has been in Microscopic Anatomy for first year medical students; served also as Coursemaster for a few years at Washington University; participation in various graduate courses on neural structure, function, and development at UMSM.

29. Thesis and Dissertation Advising:

The following have been granted (or are working toward) Ph.D. degrees for work under my direction or under the combined direction of R. Bunge (until 1996) and myself: Charles Eldridge, Ph.D.

Vincent Argiro, Ph.D. Francis Mithen, M.D., Ph.D. David Copio Rosemary Rees, Ph.D. Andy Dean, M.D., Ph.D. Valerie J. Obremski, Ph.D. James D. Guest, M.D. (1996) Marcia Castro, M.S. (1997) Gizelda Casella, M.D., Ph.D. (2001) (with Dr. P. Wood) Allison Cannon, M.S. (1998) Kevin Golden, M.D./Ph.D. student (2002-05) Ryan Williams, M.D./Ph.D. student (2003-10) Susana Cerqueira, Ph.D. student from Portugal (2012) Lucy Freer, M.D./Ph.D. student (2012 -) (with Dr. John Bethea)

Curriculum Vitae BUNGE, Mary Bartlett, Ph.D. Page -35- Dissertation Committee Member Lamya Shiabuddin, Ph.D. Jigani M. Carsi-Gabrenas, Ph.D. Nancy Stagliano, Ph.D. Heather Belmont, Ph. D. Darcie Moore Lane Coffey Jon Hertz Ephraim Trakhtenberg

Qualifying Examination Committee Member Charles Cohan, M.D. (2011) Postdoctoral Training

The following have obtained research training under my direction or under the combined direction of R. Bunge (until 1996) and myself: Susana Cerqueira, Ph.D. (postdoctoral associate, 2014-) Yee-Shuan Lee, Ph.D. (postdoctoral fellow, 2011-) Haruo Kanno, M.D., Ph.D. (postdoctoral fellow, 2010-2012) Chikato Mannoji, M.D., Ph.D. (postdoctoral fellow, 2008-2010) Ted Brindle, M.D. (Neurological Surgery Resident, 2006-2007) Edward Gamez, M.D., Ph.D. (postdoctoral fellow, 2005-2009)

Jenny Fortun, Ph.D. (postdoctoral fellow, 2005-2008) Assistant Professor, Florida Int’l University, 2008-. Caitlin Hill, Ph.D. (postdoctoral fellow, 2005-2007 and with Dr. Patrick Wood as well, 2002-2005),

Assistant Scientist, The Miami Project to Cure Paralysis (2006-2010), Assistant Professor, Cornell School of Medicine, 2010-.

Bas Blits, Ph.D., (postdoctoral fellow, 2002-2005) Senior Research Scientist, Amsterdam Molecular Therapeutics (AMT)

Lawrence Moon, Ph.D. (postdoctoral fellow, 2001-2005) Investigator, Wolfson Centre for Age-related Diseases at King’s College, London

Francisco Pereira, Ph.D. (postdoctoral fellow, 2000-2002) Assistant Professor, University of Sao Paulo Ricardo Leme, M.D. (postdoctoral fellow, 2000) Damien Pearse, Ph.D. (postdoctoral fellow, 2000-2004) Associate Professor, The Miami Project to Cure

Paralysis, University of Miami, L. Miller School of Medicine Toshihiro Takami, M.D., Ph.D., (postdoctoral fellow, 1999-2001) Assistant Professor, Neurosurgery,

Osaka Medical University Heng-Lin Yan, Ph.D. (postdoctoral fellow 1996-1999) Research Associate, Yale Univ School of Med Paul Currier, M.D. (postdoctoral fellow, 1999-2000) Pulmonary and Critical Care Unit, Massachusetts

General Hospital, Harvard Medical School, Boston Martin Oudega, Ph.D. (postdoctoral fellow, 1993-1999) Research Scientist, Kennedy Krieger Institute,

Baltimore, MD Giles Plant, Ph.D. (postdoctoral fellow, 1996-1999) Assistant Professor, University of Western Australia Wendong Wu, M.D. Ph.D. (postdoctoral fellow, 1995-1997) Practicing Neurologist Aqing Chen, M.D., Ph.D. (postdoctoral fellow, 1992-1994) Practicing Pathologist, at a Boston Hospital Xiao-Ming Xu, Ph.D. (postdoctoral fellow, 1991-1994) Professor and Mari Hulman George Chair in

Neurosciences Research Institute, Scientific Director, Spinal Cord and Brain Injury Res. Group, Indiana University School of Medicine

Cristina Fernandez-Valle, Ph.D. (postdoctoral fellow, 1989-1993) Associate Professor, University of Central Florida, Orlando, FL

Carlos Paino, Ph.D. (postdoctoral fellow, 1988-1991) Researcher at Ramon y Cajal Hospital, Madrid, Spain

Charles Eldridge, Ph.D. (Fellow, 1986-1987) Formerly completed a Fellowship, Dept. Biochemistry, Univ. Washington, Seattle


Lauren Langford, M.D., Dr. med. (Fellow, 1986-1987) Associate Pathologist, University of Texas Medical School, Houston

Naomi Kleitman, Ph.D. (Postdoctoral Fellow, 1985-1989) Program Director, NIH/NINDS March Ard, Ph.D., (Postdoctoral Fellow, 1984-1988) Associate Professor, Anatomy, Univ of Mississippi M. Blair Clark, Ph.D. (McDonnell Fellow, 1984-1986) formerly Assistant Professor Anatomy, University

of Maryland School of Medicine Keith Kuhlengel, M.D. (Postdoctoral Fellow, 1983-1986) Practicing Neurosurgeon, Lancaster, PA David Carey, Ph.D. (Postdoctoral Fellow, 1980-1982) Professor, Weis Ctr for Research, Geisinger Clinic Dikla G. Roufa, Ph.D. (Postdoctoral Fellow, 1980-1982) Fernando Moya, M.D., Ph.D. (Postdoctoral Fellow, 1979-1981) Assistant Professor of Anatomy, Facultad

de Medicina, Spain Carson Cornbrooks, Ph.D. (Postdoctoral Fellow, 1977-1982) Associate Professor of Anatomy and

Neurobiology, University of Vermont College of Medicine

Note: Some have undoubtedly been promoted and I have not been informed.

Undergraduate students Information not yet entered

SERVICE 30. University Committee and Administrative Responsibilities:

Departmental Administrative and Committee Responsibilities Search Committee for new faculty, Miami Project, 2009-2010 Space Committee for Miami Project, 2007-present

Member, Senior Advisory Committee, The Miami Project to Cure Paralysis, 2002-present Member, Faculty Search Committee, Department of Cell Biology and Anatomy, 1990-1991; to fill

available positions; second search, 1991-1992 Head of Photography and Electron Microscopy Core facilities, The Miami Project to Cure Paralysis,

1990-present Member, Graduate Education Committee, Department of Cell Biology and Anatomy, 1990-2004 Member, Committee to recruit and process postdoctoral fellow applications, The Miami Project to Cure

Paralysis, 1990-1995 Co-organizer of Knight Foundation Visiting Professor Lecture Series, The Miami Project to Cure

Paralysis, 1989-1990; 1993 Member, numerous Thesis Proposal and Dissertation Committees for doctoral candidates, WUMS. Organized new library facility for Department of Anatomy and Neurobiology, 1985-1986 Co-interviewer for and co-author of a lengthy report on the present status and future needs of the

Department, prepared for the Search Committee and prospective candidates for the Chair, 1980 Selection of cell biologists for possible faculty appointment in our Department, 1977-1978

Coursemaster, Microscopic Anatomy course for first year medical and also graduate students, 1976-1979 Chairman, Committee to choose annual Mildred Trotter Lectureship speaker, 1975-1980

Selection of cell biologists for possible faculty appointment in our Department, 1975-1976 Extra-Departmental Administrative and Committee Responsibilities

Member, Women in Academic Medicine Board, 2013- present Member, Distinguished Faculty Scholar Award Committee, 2013-present; Chair, 2014

“Brand Ambassador” for new UHealth System initiative, 2007-2011 Committee Member, Hedwig Van Ameringen Executive Leadership in Academic Medicine (ELAM)

Program for women offered by MCP Hahnemann University in Pennsylvania, 2000


Member, Committee for Richard P. Bunge Lectureship in Neuroscience, 1997-present Member, Committee to choose and arrange annual MBB Distinguished Women in Cell Biology Lecture

Series, 2005-present (includes mentoring sessions) Member, Committee to choose awardees of Reeve Medal (UC/Irvine) for many years to present Member, Search Committee for Chair of Neurology, 2005-2007 Member, Committee to nominate faculty members for a Howard Hughes Medical Institute grant, 2004

Member, Search Committee for Director of the Evelyn McKnight Ctr for Memory Disorders, 2003-2004 Participant in successful second request to the W.A. Coulter Foundation for funding for a Cellular

Biotechnology Center on the medical campus Member, Search Committee for the Chair of the Department of Psychiatry and Behavioral Sciences,

2002-present Member, Advisory Committee for Faculty Development, 2002 Member, Committee for selection of Medical School’s participant in ELAM program (nationwide

leadership program), 2000, 2002 Academic Personnel Board, 1999-2000

Invited Grass Traveling Scientists to speak at Neuroscience Day; Marcus Raichle (1998), Patricia Goldman-Rakic (1999)

Participant, newly organized mentoring program for new faculty Member, Strategic Task Force convened by Dean Clarkson for upcoming campaign

Member Ad Hoc Committee to prepare document, Guidelines for Chair Search Committees (for Faculty council), 1998

Member, Search Committee for Associate Dean of Research and Graduate Studies, 1998- 2000 Member, Provost’s Scholarly Awards Review Committee, 1997 Member, Faculty Research Advisory Committee of the Faculty Council, University of Miami School of

Medicine, 1997 Member, Comm to study the Department of Cell Biology and Anatomy for potential restructuring, 1997

Member, Search Committee, Chair of the Department of Medicine, 1996-1997 Head, Lois Pope LIFE Foundation Fellowship Committee, 1996-2009 Member, Search Committee, Scientific Director of the Miami Project to Cure Paralysis, 1995-1996 Member, Search Committee, Chair of the Department of Ophthalmology, 1994-1995 Member, Search Committee, Chair of Department of Microbiology and Immunology, 1993-1994 Participant in the Winter Workshop (to interest college students in graduate school), 1992-present Senior Fellow, The Miami Project to Cure Paralysis, 1991-present Member, Search Committee, Chair of Department of Biochemistry and Molecular Biology, 1991-1993

Member, Sexual Harassment Committee, University of Miami Head of Committee that created poster for the Neuroscience Program

Member, Neuroscience Program Steering Committee, University of Miami, 1990-2000 One of a small group responsible for launching new university- wide, Ph.D. granting

Neuroscience Program (1989-90) Interviewing, Physician-Scientist Program, 1990-1991 Member, Promotion and Tenure Committee, University of Miami School of Medicine, 1990-1993 Member, Thesis Proposal and Dissertation Committees for numerous doctoral candidates Member, Committee to create a brochure describing the Neural Science Program, 1988 One of a group of three to create a recruiting poster for the Cell Biology Program, 1988 Initial Member, Committee on Research Integrity of the School of Medicine, 1988-1989 Neural Science Graduate Admission Committee, 1987-1988 Member, Steering Committee for new Cell Biology Program of the Division of Biology and Biomedical

Sciences, 1987-1988 Member, Erlanger Society, 1986-1989 Member, Admissions Committee for M.D./Ph.D. students, 1984

Member, Seminar Committee for Cell and Molecular Biology Programs, 1982-1984 Member of a group which organized and taught a new Cell Biology course for 1st year med students, 1982


Member, Steering Committee of the Integrative and Cell Biology Program of the Division of Biology and Biomedical Sciences. (Also, in charge of Preliminary Examinations in the area of “General Cell Biology” for graduate students.) 1980-1984

Committee on Academic Review and Promotions, I, 1976-1979 Chairman, Nominating Committee for Faculty Council, 1976

31. Community Activities:

Member, Board of the Florida Women of Achievement, 2011 - present. Member, Advisory Council, Coral Gables @ Home Foundation, 2008-2011

With money from the Lois Pope LIFE International Research Award, completed principal needed to support the Richard P Bunge Memorial Neuroscience Lecture Series and contributed principal to establish a new MBB Distinguished Women in Cell Biology Lecture Series, 2005 Talk: Spinal Cord Injury, UM Osher Institute, 2011 Talk: Opportunities and Challenges for students at the Miami Museum of Science on behalf of the FL Women of Achievement, 2006

Commissioned and donated museum-quality glass sculpture (by Jon Kuhn) to the University of Miami to remember and honor Richard P. Bunge, M.D., 2001

Speaker, University of Miami/Dade County Women’s Guild luncheon, 1997 Laboratory demonstration to the Dade County Public Schools’ Advanced Internship Program (Brain

Awareness Week), 1997 Guest speaker, MDCC (North Campus), “Career Options for Today’s Women”, 1994 Accept high school students to work in the laboratory in the Community Laboratory Research Program,

Dade County Public Schools Participate in fund-raising activities for The Miami Project to Cure Paralysis, such as the Walk-a-thon, the

Women's Guild annual luncheon and other charity events (90s) Provide some support for the Arts in Miami, particularly at the Lowe Museum.

Commissioned museum-quality glass sculpture by Dale Chihuly for Washington University School of Medicine, 1982. Mr. Chihuly is now regarded as the foremost glass artist in the United States if not internationally, with pieces in over 175 museums throughout the world.

Documents

UNIVERSITY OF MIAMIUNIVERSITY OF MIAMI . CURRICULUM VITAE . MARY BARTLETT BUNGE, Ph.D. 1. Date: June 8, 2015 . PERSONAL 2. Name: 3. Home Phone: Mary Bartlett Bunge …phydatabase.med.miami.edu/documents/cv/Bartlett... ·