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USAMRIID Pathology Division USAMRIID Pathology Division African green monkey (Chlorocebus

USAMRIID Pathology Division African green monkey (Chlorocebus aethiops)

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Page 1: USAMRIID Pathology Division African green monkey (Chlorocebus aethiops)

USAMRIID Pathology DivisionUSAMRIID Pathology Division

African green monkey (Chlorocebus aethiops)

Page 2: USAMRIID Pathology Division African green monkey (Chlorocebus aethiops)

USAMRIID Pathology DivisionUSAMRIID Pathology Division

Page 3: USAMRIID Pathology Division African green monkey (Chlorocebus aethiops)

USAMRIID Pathology DivisionUSAMRIID Pathology Division

Day 7: Surgery• Ulcerative and

hemorrhagic colitis with a thickened colon occluding the lumen 10-13 cm proximal to anus

• Euthanasia and necropsy

• Additional colonic and gingival culture swabs submitted

Page 4: USAMRIID Pathology Division African green monkey (Chlorocebus aethiops)

USAMRIID Pathology DivisionUSAMRIID Pathology Division

Gross Pathology• Colitis, ulcerative and hemorrhagic, segmental,

moderate, with mucosal sloughing

Colon with hemorrhage & Colon with hemorrhage & pseudomembranepseudomembrane

Cecum with adherent, Cecum with adherent, sticky fecal materialsticky fecal material

Ileum

pseudomembrane

Page 5: USAMRIID Pathology Division African green monkey (Chlorocebus aethiops)

USAMRIID Pathology DivisionUSAMRIID Pathology Division

BA

C D

Page 6: USAMRIID Pathology Division African green monkey (Chlorocebus aethiops)

USAMRIID Pathology DivisionUSAMRIID Pathology Division

• Culture results:

Positive for Shigella from rectal swab, colon, and gingiva

• Growth was not speciated

Gingival hyperplasia with Gingival hyperplasia with periodontitisperiodontitis