USC School ofPharmacy

Founded in 1905, the USC School of Pharmacy is the oldest and foremost pharmacy

school in Southern California. In 2005 the school will celebrate its 100-year anniversary –

a milestone in pharmacy education and research. Approximately 50 percent of the prac-

ticing pharmacists in Southern California are graduates of USC. The school has an average student

body of 713 full-time students in the professional program, 87 students in the Master of Science

and Doctor of Philosophy programs, a full-time faculty of 70 and more than 355 part-time and vol-

unteer faculty.

The school occupies state-of-the-art facilities on the USC Health Sciences campus in metropolitan

Los Angeles, adjacent to the Los Angeles County + USC Medical Center (one of the largest teach-

ing hospitals in the country), the USC/Norris Comprehensive Cancer Center, the Doheny Eye

Institute and the USC University Hospital. USC pharmacy students receive clinical training at these

facilities and many other affiliated hospitals, health care clinics, skilled nursing facilities, home

health care agencies and pharmacies in the Southern California region. Recognized as one of the

most innovative schools of pharmacy in the nation, the USC School of Pharmacy serves as a model

for other progressive pharmacy schools. USC was the first to establish the six-year program leading

to the Doctor of Pharmacy degree as the first professional degree. In 1968, USC initiated one of

the first clinical pharmacy programs in the nation. In 1988, the school started a Pharm.D./M.B.A.

dual degree program, the first of its kind in the country. In collaboration with the Andrus

Gerontology Center, a Pharm.D./Graduate Certificate in Gerontology was developed in 1990.

In 1994, the school implemented the M.S. and Ph.D. programs in Pharmaceutical Economics

and Policy, also the first of their kind in the country. In 2001, additional dual degree programs

were introduced including the Pharm.D./J.D., the Pharm.D./M.S. in Regulatory Science and

the Pharm.D./Master of Public Health, and in 2003, the school initiated the Pharm.D./M.S. in

Gerontology.

The school is a member of the American Association of Colleges of Pharmacy, which promotes the

interests of pharmaceutical education. All institutions holding membership must maintain certain

minimum requirements for entrance and graduation. The school is accredited by the American

Council on Pharmaceutical Education.

Associate Professor Kathleen A. Johnson, (backrow), developed the FUENTE Initiative toconnect the USC School of Pharmacy and thecommunity through health education programs.Pharmacy students receive hands-on experienceby leading neighborhood health fairs andteaching poison prevention techniques.

Health Sciences CampusJohn Stauffer Pharmaceutical SciencesCenter 1985 Zonal Avenue, Los Angeles,CA 90089-9121(323) 442-1369 Office of the DeanFAX: (323) 442-1681(323) 442-1466 Office of Admission andStudent AffairsEmail: pharmadm@usc.eduEmail: pharmfa@usc.eduwww.usc.edu/hsc/pharmacy

AdministrationTimothy M. Chan, Ph.D., Dean

Fred G. Weissman, Pharm.D., J.D., AssociateDean, Academic and Clinical Affairs

Cynthia C. White, B.A., Associate Dean,Administrative Affairs

Ronald L. Alkana, Pharm.D., Ph.D., AssociateDean, Curricular Development

Michael Z. Wincor, Pharm.D., Associate Dean,External Programs

Melvin F. Baron, Pharm.D., Assistant Dean,Programmatic Advancement

FacultyUniversity Professor and Boyd P. and Elsie D.Welin Professorship in Pharmaceutical Sciences:Jean Chen Shih, Ph.D.

Distinguished Professor: Walter W. Wolf, Ph.D.

John Stauffer Dean’s Chair in PharmaceuticalSciences: Timothy M. Chan, Ph.D.

John A. Biles Professorship in PharmaceuticalSciences: Sarah Hamm-Alvarez, Ph.D.

Timothy M. Chan Professorship inComplementary Therapeutics: Rajindar S. Sohal,Ph.D.

Charles Krown/Pharmacy Alumni Professorshipin Pharmaceutical Sciences: Enrique Cadenas,M.D., Ph.D.

QSAD Centurion Professorship in PharmaceuticalSciences: Michael B. Nichol, Ph.D.

Professors: Ronald L. Alkana, Pharm.D., Ph.D.;David K. Ann, Ph.D.; Roberta D. Brinton,Ph.D.; Enrique Cadenas, M.D., Ph.D.;Timothy M. Chan, Ph.D.; Alex Sevanian,Ph.D.; Wei-Chiang Shen, Ph.D.; Jean C.Shih, Ph.D.; Rajindar Sohal, Ph.D.; Walter W.Wolf, Ph.D.

Associate Professors: James D. Adams, Jr.,Ph.D.; Michael B. Bolger, Ph.D.; Roger F.Duncan, Ph.D.; Sarah F. Hamm-Alvarez,Ph.D.; Ian S. Haworth, Ph.D.; Joel W. Hay,Ph.D.; Jeffrey S. McCombs, Ph.D.(Gerontology); Michael B. Nichol, Ph.D.;Curtis T. Okamoto, Ph.D.

Assistant Professors: Jeonghoon Ahn, Ph.D.;Denise Globe, D.C., Ph.D.; Nouri Neamati,Ph.D.; Clay C.C. Wang, Ph.D.; Austin Yang,Ph.D.

Research Associate Professors: Kevin J.Y.H. ShinChen, Ph.D.; Natalie S. Cohen, Ph.D.

Research Assistant Professors: Daryl L. Davies,Ph.D.; Robin Mockett, Ph.D.; Hadi Moini,Ph.D.; Jon Nilsen, Ph.D.; Ha-Van Nguyen,Ph.D.; Igor Rebrin, Ph.D.

Professors of Pharmacy: Gilbert Burckart,Pharm.D.; Mark A. Gill, Pharm.D.; Glen L.Stimmel, Pharm.D. (Psychiatry and theBehavioral Sciences)

Associate Professors of Pharmacy: Melvin F.Baron, M.P.A., Pharm.D.; Paul M. Beringer,Pharm.D.; Kathleen H. Besinque, Pharm.D.,M.S.Ed.; Alfred Chin, Pharm.D.; Julie A.Dopheide, Pharm.D. (Clinical Psychiatry andthe Behavioral Sciences); Kevin L. Forrester,Pharm.D.; William C. Gong, Pharm.D.; MaryA. Gutierrez, Pharm.D.; Kathleen A. Johnson,Pharm.D., M.P.H., Ph.D. (PharmaceuticalEconomics and Policy); Mervyn K. Kalman,M.B.A.; Jack W. Kern, Pharm.D.; CynthiaL.L. Lieu, Pharm.D.; Stanley G. Louie,Pharm.D. (Family Medicine); Gladys H. Mitani,Pharm.D.; Irving Steinberg, Pharm.D.(Clinical Pediatrics); Gregory A. Thompson,Pharm.D.; Fred G. Weissman, Pharm.D.,J.D.; Bradley R. Williams, Pharm.D. (ClinicalGerontology); Michael Z. Wincor, Pharm.D.(Clinical Psychiatry and the Behavioral Sciences);Annie Wong-Beringer, Pharm.D.; Frances S.Wong, Pharm.D.

Assistant Professors of Pharmacy: Betty Chan,Pharm.D.; Steven Chen, Pharm.D.; JenniferH. Cupo, Pharm.D.; Paul J. Donatoni,Pharm.D.; Jeffery Goad, Pharm.D.; EmilyHan, Pharm.D.; Kevin Kaneko, Pharm.D.;Jiwon Kim, Pharm.D.; Kum Ja K. Lee,Pharm.D.; May C. Mak, Pharm.D.; Tien Ng,Pharm.D.; Thuy N. Nguyen, Pharm.D.; PaulaPhongsamron, Pharm.D.; Maria I. Rudis,Pharm.D. (Emergency Medicine); FlorenceH.Wong-Yu, Pharm.D.

Distinguished Emeritus Professors: John A. Biles,Ph.D.; Paul Hochstein, Ph.D.

Emeritus Professor: Glenn H. Hamor, Ph.D.

ProgramsThe School of Pharmacy offers curricula lead-ing to the Doctor of Pharmacy (Pharm.D.)degree. Through the Graduate School, grad-uate degrees offered are: Master of Science(M.S.) and Doctor of Philosophy (Ph.D.) inpharmaceutical sciences, Master of Science(M.S.) and Doctor of Philosophy (Ph.D.) inmolecular pharmacology and toxicology,Master of Science (M.S.) and Doctor ofPhilosophy (Ph.D.) in pharmaceutical eco-nomics and policy, Master of Science (M.S.)in Regulatory Science. Four dual degreeprograms, one joint program and one certifi-cate program are also offered: Pharm.D./J.D., Pharm.D./M.B.A., Pharm.D./M.P.H.,Pharm.D./M.S., Regulatory Science,Pharm.D./Ph.D., Pharm.D./M.S., Gerontologyand Pharm.D./Graduate Certificate inGerontology.

The University of Southern California’sDoctor of Pharmacy and Master of Scienceprograms are accredited by the AmericanCouncil on Pharmaceutical Education, 311West Superior Street, Suite 512, Chicago,IL 60610, (312) 664-3575, (800) 533-3606, orFAX (312) 664-4652.

Tuition and Fees (Estimated)Tuition for School of Pharmacy degree pro-grams (Pharm.D.; M.S. and Ph.D. in pharma-ceutical sciences; M.S. and Ph.D. in molecu-lar pharmacology and toxicology; M.S. andPh.D. in pharmaceutical economics and poli-cy) is charged at the following rate (whichdiffers from standard USC tuition): persemester (15-18 units) $15,403; for less than15 units and each unit above 18 units, $1,028per unit. See the Tuition and Fees section,page 30, for fee information. These fees arebased upon current information available atthe time of publication and are subject topossible later change.

Doctor of Pharmacy students must pay a$500 non-refundable acceptance deposit thatis applicable toward tuition. For depositinformation in other degree programs in theSchool of Pharmacy, please consult appropri-ate offices.

728 USC School of Pharmacy

Honor SocietiesRho ChiTheta chapter of Rho Chi, national honorarypharmaceutical society, was established atUSC in 1925. Charters for chapters of thisorganization are granted only to studentgroups in those colleges that are members ingood standing of the American Association ofColleges of Pharmacy. Eligibility for mem-bership is based on high attainment in schol-arship, character, personality and leadership.All candidates selected for membership musthave completed two years of college work,and they must be approved by the Dean ofthe School of Pharmacy.

Phi Lambda SigmaThe Phi Lambda Sigma chapter was estab-lished at USC in 1988. This national pharmacyleadership society is devoted to identifying,supporting and recognizing the contributionof pharmacy students to their colleges, theirclassmates, their campuses, their communi-ties and to their chosen profession.

Student Housing and Service Facility,Health Sciences CampusThere are limited university-managedaccommodations on the Health Sciencescampus. Students may wish to live in studenthousing on the University Park campus,located about eight miles from the HealthSciences campus.

The Blanche and Frank R. Seaver StudentResidence, adjacent to the John StaufferPharmaceutical Sciences Center, providesdining facilities and a book store. For resi-dence information, phone (323) 442-1576; forbookstore information call (323) 442-2674.

Student Health Services, Health SciencesCampusServices of the Student Health Center, cov-ered by the mandatory student health fee,include the usual ambulatory care healthservices given by the faculty of the USCDepartment of Family Medicine and theStudent Health Center nursing staff. Hoursare from 8:30 a.m. to 4:30 p.m., Mondaythrough Friday, excluding USC holidays. TheStudent Health Center is located in the USCHealth Care Consultation Center, 1500 SanPablo Street, Suite 104, adjacent to the USCUniversity Hospital, one block northeast ofthe School of Pharmacy. The telephone num-ber is (323) 442-5980. In addition to the stu-dent health fee, all Pharm.D. students musthave major medical insurance coverage fromthe USC Health Plan. A student may requesta waiver of the USC Health Plan if coveredby a personal medical plan acceptable to theHealth Insurance Office.

Professional Degrees 729

Professional Degrees

A four-year curriculum, following appropriatecollege prerequisite work, leading to theDoctor of Pharmacy (Pharm.D.) is offered tostudents admitted to the School of Pharmacy.A sample outline of the curriculum is listed inthe following pages. The degree will not beconferred until the student has successfullycompleted all Doctor of Pharmacy degreerequirements.

Application ProcedureThe School of Pharmacy uses the CollegeApplication Service (PharmCAS) and a sup-plemental application for its admissionprocess. Applications are available atwww.usc.edu/hsc/pharmacy. The PharmCASand supplemental application deadline isJanuary 1 (subject to change).

Applications received before January 1 willhave priority interview consideration whenthe PharmCAS and supplemental applicationare submitted and all necessary criteria havebeen met. Follow the instructions carefullysince PharmCAS is filed electronically andthe supplemental application is maileddirectly to the USC School of Pharmacy.

Evaluation of official transcripts is completedby the School of Pharmacy AdmissionsCommittee and a letter of acceptance ismailed to each applicant who qualifies forentrance. All documents mailed directly tothe School of Pharmacy and received fromPharmCAS by the Office of Admissionbecome the property of the university andcannot be returned or duplicated for otherthan university purposes.

Admissions GuidelinesThe Admissions Committee considers sever-al factors in making admissions decisions:strong academics; competitive performancein the interview; recommendation forms; andwritten comments specified in the applica-tion. The committee also considers a candi-date’s motivation to pursue pharmacy, stronginterpersonal skills, excellent oral and writtencommunication skills, and leadership abili-ties. While the School of Pharmacy givesequal consideration to every qualified appli-cant, the school cannot accommodate allqualified candidates who apply for admission.

Admission of International StudentsAlthough international students are subject tospecial admission procedures, which are spec-ified in the Admission section of this cata-logue, they must follow the application pro-cedures used by domestic students.

Entrance RequirementsAdmission to the School of Pharmacy requires:completion of the prerequisite college courses(approximately 90 semester or 135 quarterunits) and a minimum 3.0 (A = 4.0) cumula-tive grade point average based on all transfer-able college course work.

Candidates who have received or will receivea baccalaureate degree or who have complet-ed units in excess of the minimum requiredwill be considered more favorably than appli-cants who have fulfilled only minimumrequirements.

Doctor of Pharmacy

Prepharmacy RequirementsTo be eligible for admission to the School ofPharmacy, students must take the requiredprerequisite college courses (approximately 90semester units or 135 quarter units) includinggeneral chemistry, organic chemistry, generalbiology, physics, biochemistry, molecular biol-ogy, microbiology, mammalian physiology, cal-culus, statistics, general psychology or intro-duction to sociology, macroeconomics ormicroeconomics, interpersonal communica-tion, English and electives from the socialand behavioral sciences and humanities.These requirements may be completed atany accredited two-year or four-year collegeor university.

Grades of pass/no pass will not be accepted(unless a course is only offered on a pass/nopass basis).

Mathematics and Physical SciencesCourses must include calculus, statistics, gen-eral chemistry and organic chemistry. Onlycourses for science majors are acceptable. It ishighly recommended that math and sciencecourses be completed during the regular aca-demic year and not during a summer term.

Calculus: one semester or two quarters ofcalculus are required. The course shouldinclude differential and integral calculus forscience majors. The recommended course atUSC is MATH 125.

Statistics: One course is required.

General chemistry: a one-year course for sci-ence majors, including laboratory, is required.The course should include inorganic chem-istry and qualitative analysis. The recom-mended courses at USC are CHEM 105aLbL.

Organic chemistry: a one-year course for sci-ence majors, including laboratory, is required.If the school offers less than a one-yearcourse, the student must complete the secondsemester at another institution. The recom-mended courses at USC are CHEM 322abL.

Physics: a one-year course in physics forscience majors, including laboratory, isrequired. The recommended courses atUSC are PHYS 135abL or PHYS 151L andPHYS 152L.

Biological SciencesGeneral biology: a one-year course for sciencemajors is required in general biology withlaboratory, for science majors (excludingcourses in human anatomy, human physiolo-gy, botany and microbiology). If the schooloffers less than a one-year course, the studentmust complete the second semester at anoth-er institution. The recommended courses atUSC are BISC 120L and BISC 220L.

Microbiology (with lab): one course in micro-biology for science majors, including laborato-ry, is required. The recommended course atUSC is BISC 300L.

Molecular biology: one course in molecularbiology for science majors is required. Therecommended course at USC is BISC 311.

Biochemistry or cell biology: one coursein biochemistry or cell biology for sciencemajors is required. The recommended courseat USC is BISC 316L.

Mammalian physiology: one course in mam-malian physiology for science majors, withlaboratory, is required. The recommendedcourse at USC is BISC 307L.

EnglishTwo semesters or three quarters of composi-tion (or two quarters of composition and onequarter of literature) are required. RemedialEnglish and English as a Second Language(ESL) are not acceptable. An English profi-ciency examination may be required.

CommunicationsOne course (one semester or one quarter) ininterpersonal communications is required.The course should include core theories ofmessage production and reception in bothinterpersonal and public contexts. Onesemester or one quarter is required. The rec-ommended courses at USC are COMM 200,COMM 201, COMM 204, COMM 304 orCOMM 308.

Social and Behavioral SciencesPsychology or Sociology: one course in gener-al psychology or introduction to sociology isrequired. The recommended courses at USCare PSYC 100 or SOCI 200.

Economics: one course in either macro-economics or microeconomics is required. If aone-year course is offered, both semesters maybe taken and excess units may be applied toeither the remainder of the unit requirementsfor the subject area or as elective units. Theequivalent course at USC is ECON 203 orECON 205.

Students who have earned a baccalaureatedegree and meet the prerequisites describedabove (including general psychology or intro-duction to sociology and microeconomics ormacroeconomics) at the time of admission willhave fulfilled the requirement for social andbehavioral sciences.

Students who will not have earned a baccalau-reate degree at the time of admission mustcomplete an additional two semesters or threequarters of courses in the social and behav-ioral sciences. Recommended areas includeanthropology, psychology, psychobiology, eco-nomics, geography and sociology.

HumanitiesStudents who have earned a baccalaureatedegree and meet the prerequisites describedabove at the time of admission will have ful-filled the requirements for humanities.

Students who will not have earned a bac-calaureate degree at the time of admissionmust complete an additional two semesters orthree quarters of courses in literature, philos-ophy, history, ethics, foreign language or finearts. Studio or performance classes in art andmusic are not acceptable.

Advanced Placement ExaminationThe Admissions Committee recommendsthat applicants enroll in all of the requiredprepharmacy courses. Advanced Placementexaminations are not granted equivalent statusas specific courses and do not fulfill any of theprepharmacy requirements. For students whomay have been waived out of any prepharma-cy requirement, the committee generally willconsider the application of higher level coursework toward prepharmacy requirements.Please contact the School of Pharmacy Officeof Admission for specific information.

Entrance ExaminationsAn entrance examination (PPBE, PCAT) isnot required; an interview will be requiredfor admission.

Transfer StudentsTransfer students from other U.S. accreditedcolleges of pharmacy are not accepted intothe Pharm.D. program.

Post-Baccalaureate ProgramThe School of Pharmacy accepts a limitednumber of applicants (if vacancies exist)who hold a recently conferred baccalaureatedegree in pharmacy from a college ofpharmacy accredited by the AmericanCouncil on Pharmaceutical Education. Suchapplicants may not be required to meet allprepharmacy requirements in order to qualifyfor admission and, if admitted to the Doctorof Pharmacy program, may be accepted at anadvanced level for a minimum of two years(72 semester units) of full-time study.

Special Admissions Program for HighSchool Students and USC UndergraduatesThe Trojan Admission Prepharmacy (TAP)program provides guaranteed admission to theUSC School of Pharmacy for USC undergrad-uates who meet preset performance standards.The TAP program has been designed toattract highly qualified, mature high schoolseniors to apply to USC and take theirprepharmacy course work at USC beginningas first semester freshmen. The program alsoallows USC undergraduates to apply to theTAP program after completing 32-48 semesterunits of undergraduate course work at USC.

730 USC School of Pharmacy

Students are not eligible for the TAP programif they have completed more than 48 semesterunits of prepharmacy course work. Admissionrequirements for high school applicants to theTAP program include prior admission to aUSC undergraduate program and satisfactoryscores on the TAP program admission inter-view and entrance essay. Minimum admissionrequirements for eligible second year USCundergraduates include completion of 32-48semester units of pharmacy prerequisite cours-es at USC, a minimum cumulative USC GPAof 3.4 and satisfactory scores on the TAP pro-gram admission interview and entrance essay.

Students accepted into the TAP program musttake full course loads each semester (mini-mum of 16 units) and complete their prephar-macy requirements with at least a 3.2 cumula-tive GPA. All prepharmacy courses must betaken during the fall and spring semesters atUSC for letter grades. Summer school at USCor elsewhere, credit/no credit grades andgrades of D and lower are not acceptable.

TAP program participants who fulfill therequirements listed above will be guaranteedadmission to the Doctor of Pharmacy programat USC. Participants who fulfill the prephar-macy requirements and TAP GPA require-ments and wish to complete their baccalaure-ate degree can do so without losing theirguaranteed admission to the School ofPharmacy, provided they meet or exceed theminimum cumulative GPA required for admis-sion into the Pharm.D. program. TAP programstudents receive ongoing individual advise-ment, access to the School of Pharmacy’s stu-dent services and the privilege of joining thePrepharmacy Club. A specific listing of USCcourses and a recommended program for TAPprogram participants can be obtained from theSchool of Pharmacy Office of Admission.

General Education Requirements (TAP StudentsOnly)The university’s general education programprovides a coherent, integrated introductionto the breadth of knowledge you will need toconsider yourself (and to be considered byother people) a generally well-educated per-son. This new program requires six courses indifferent categories, plus writing and diversi-ty requirements, which are described indetail on pages 183 through 187.

Pharm.D. Curriculum RequirementsThe completion of a four-year professionalcurriculum is required to earn the Doctor ofPharmacy degree. The curriculum, except forthe fourth year, is a “block” program. All stu-dents must enroll in 18 units each semesterin courses designed for that year, falland spring. Students do not have choices of

courses to take nor are they permitted todrop any one course or courses during thesemester. (Year II and III students have elec-tive course choices). Progress is permittedonly when the prior semester is completedin full. Students should view the curriculumoutlined here as advisory only and subjectto modification. “Hours” are substitutedfor “units” in identifying acceptable timerequirements for completion of the programstages. Aggregate hours must equal a mini-mum of 144 units/hours.

Program of CoursesYEAR I, FALL (18 HOURS) UNITS

PHRD 501 Pharmaceutics I 4PHRD 503 Biological Systems I 5PHRD 505 Molecular Genetics

and Therapy 2PHRD 507 Health Care Delivery

Systems 2PHRD 509 Pharmacy Practice

and Experience I 5

YEAR I, SPRING (18 HOURS) UNITS

PHRD 502 Pharmaceutics II 3PHRD 504 Biological Systems II 5PHRD 506 Over-the-Counter

Pharmacy Products 4PHRD 508 Pharmacy Literature

Review and StatisticalAnalysis 2

PHRD 510 Pharmacy Practiceand Experience II 4

Total Year I: 36 hours

YEAR II, FALL (18 HOURS) UNITS

PHRD 551 Immunology 3PHRD 553 Management within

Health Care Organizations 2PHRD 555 Biochemical and Molecular

Sites of Drug Action 4PHRD 557 Therapeutics I 5PHRD 559 Therapeutics II 2PHRD 561 Parenteral Therapy

Externship 2

YEAR II, SPRING (18 HOURS) UNITS

PHRD 552 Pharmaceutics IV 3PHRD 554 Public Health and

Epidemiology 2PHRD 560 Therapeutics III 6PHRD 562 Therapeutics IV 4PHRD 561 Parenteral Therapy

Externship (credit fall)Elective 1 3

Total Year II: 36 hours

YEAR III, FALL (18 HOURS) UNITS

PHRD 601 Therapeutics V 6PHRD 603 Therapeutics VI 3PHRD 605 Therapeutics VII 4PHRD 607 Nutrition 2Elective 2 3

YEAR III, SPRING (18 HOURS) UNITS

PHRD 606 Therapeutics VIII 2PHRD 608 Therapeutics IX 2PHRD 610 Therapeutics X 3PHRD 612 Therapeutics XI 2PHRD 614 Pharmaceutical Economics

and Outcome Studies 3PHRD 616 Pharmacy Law and Ethics 3Elective 3 3

Year II and III students must choose theirelectives from the following (3 units each):PHRD 651 Community Pharmacy IPHRD 652 Community Pharmacy IIPHRD 653 Health Systems Pharmacy IPHRD 654 Health Systems Pharmacy IIPHRD 655 Geriatric Pharmacy IPHRD 656 Geriatric Pharmacy IIPHRD 657 Basic Research DesignPHRD 658 Sleep and the Pharmacologic

Management of Its DisordersPHRD 659 Molecular Therapeutics:

Signal TransductionPHRD 660 Disease State Management IPHRD 661 Pharmacy Practice in

Women’s HealthPHRD 662 Psychiatric Pharmacy

PracticePHRD 663 Pharmaceutical

DevelopmentPHRD 664 Clinical Problem SolvingPHRD 665 Complementary/Alternative

TherapeuticsPHRD 666 Therapeutic Drug

MonitoringPHRD 667 Drugs of AbusePHRD 668 Computing ApplicationPHRD 669 Health Care Needs of

Special PopulationsPHRD 670 Marketing and Development

in the Pharmaceutical Industry

Total Year III: 36 units

YEAR IV, FALL (18 HOURS)

Required ClerkshipsElective Clerkships

YEAR IV, SPRING (18 HOURS)

Required ClerkshipsElective Clerkships

Total Year IV: 36 units

Professional Degrees 731

Required Clerkships (6 units each) — fourrotations:PHRD 701 Acute Care Clinical Practice

ClerkshipPHRD 705 Community Pharmacy

ClerkshipStudents must select Option A or Option B:Option APHRD 702 Inpatient Psychiatric ClerkshipPHRD 704 Primary Care Clerkship

Option BPHRD 707 Outpatient Psychiatric Pharmacy

ClerkshipPHRD 7XX Inpatient Elective

Elective Clerkships — two rotations:PHRD 702* Inpatient Psychiatric Pharmacy

ClerkshipPHRD 703 Long Term Care ClerkshipPHRD 706 Geriatrics ClerkshipPHRD 708* Inpatient Clinical Practice

ClerkshipPHRD 709* Pediatric Drug Therapy

ClerkshipPHRD 710* Surgery ClerkshipPHRD 711* Cardiovascular Drug Therapy

ClerkshipPHRD 712* Applied Clinical

Pharmacokinetics ClerkshipPHRD 713 Drug Information ClerkshipPHRD 714 Radiopharmacy ClerkshipPHRD 715* Oncology ClerkshipPHRD 716* Ob-Gyn ClerkshipPHRD 717 Dermatology ClerkshipPHRD 718 Hospital Pharmacy Practice

ClerkshipPHRD 719 Pain Management Clerkship

PHRD 720* Critical Care ClerkshipPHRD 721 Drug Utilization and Evaluation

ClerkshipPHRD 722 Home Health Care ClerkshipPHRD 723* Nutritional Support ClerkshipPHRD 724 Advanced Community Pharmacy

ClerkshipPHRD 725 International Pharmacy

ClerkshipPHRD 726 Directed Clinical Project

Clerkship IPHRD 727 Directed Clinical Project

Clerkship IIPHRD 728 Directed Clinical Project

Clerkship IIIPHRD 729 Directed Clinical Project

Clerkship IVPHRD 730 Acute Care Geriatrics ClerkshipPHRD 731 Advanced Geriatrics ClerkshipPHRD 732 Pharmacy Administration

ClerkshipPHRD 733* Anticoagulation Therapy

ClerkshipPHRD 734* Antimicrobial Therapy ClerkshipPHRD 735 Clinical Pharmacy Research

ClerkshipPHRD 736* Chemical Dependency ClerkshipPHRD 737* Clinical Transplantation

ClerkshipPHRD 738 Pharmaceutical Industry

ClerkshipPHRD 739 AIDS/Immune Disorders

ClerkshipPHRD 740 Health Care Systems

Administration Clerkship

*Acceptable for satisfying the inpatient electiverequirement.

Total for Pharm.D. degree: 144 semesterunits (hours).

Degree RequirementsAll students in the Doctor of Pharmacydegree program must meet course require-ments, grade point average requirements andprogram residency requirements. All courserequirements must be completed with agrade of “C” or better. The degree will notbe conferred until the student has successful-ly completed all Doctor of Pharmacy degreerequirements. Students are subject to thedegree requirements in the USC Cataloguecurrent for the semester of their admissioninto the Doctor of Pharmacy program.Students must have a cumulative grade pointaverage of 3.0 in the Pharm.D. curriculum tomeet graduation requirements.

RegistrationDetails of the School of Pharmacy registrationprocedure will be included in the orientationprogram prior to the first week of classes.

Cancellation of RegistrationDuring the first three years of the Doctorof Pharmacy program (Years I, II and III), astudent will only be permitted to withdrawfrom all courses enrolled in a semester andmay not selectively withdraw from a singlecourse or group of courses. During the fourthyear, students must contact the School ofPharmacy Office of Admission and StudentAffairs for withdrawal guidelines. Proceduresfor readmission into the program or make-upof incomplete courses and clerkships areincluded in the school’s brochure on academ-ic policies and procedures.

732 USC School of Pharmacy

The School of Pharmacy, through theGraduate School, offers curricula leading tothe M.S. and Ph.D. degrees in pharmaceuti-cal sciences and in molecular pharmacologyand toxicology. The school also offers aninterdisciplinary M.S. in regulatory science.The Ph.D. degree in pharmaceutical eco-nomics and policy is offered jointly with theDepartment of Economics. The M.S. degreein pharmaceutical economics and policy isoffered jointly with the School of Policy,Planning, and Development and theDepartment of Economics. In addition, theschool offers dual degrees with the schoolsof law, business and gerontology as well as

other programs. Instructions given in theAdmission section of this catalogue are to befollowed, but the application and the supple-mental information requested should first besubmitted to: Graduate Programs Office, USCSchool of Pharmacy, 1985 Zonal Avenue, LosAngeles, CA 90033. Additional informationmay be obtained by calling (323) 442-1474 orsending email to pharmgrd@usc.edu.

Admission Requirements for the Master ofScience and Doctor of Philosophy inPharmaceutical SciencesApplicants should possess a bachelor’s degreeor equivalent from an accredited college oruniversity. A minimum grade point average of

3.0 and qualifying scores on the GRE in theverbal and quantitative tests are required. Inaddition to excellent communication skills,applicants should possess knowledge andcompetence equivalent to one year of accept-able course work in at least three of thefollowing disciplines: mathematics, organicchemistry, physical chemistry, biochemistry,physiology and pharmacology. In addition tothe application for admission, three letters ofrecommendation from faculty members whocan evaluate the promise of the applicantfor graduate study and a personal statementsummarizing career objectives and researchinterests must be submitted.

Graduate Degrees

Applicants who do not meet all the specificrequirements indicated above, but who showunique potential, may be considered foradmission with conditions which may be ful-filled during the first semester of enrollment.See the Graduate School section of this cata-logue, page 601.

Admission Requirements for the Master ofScience and Doctor of Philosophy inMolecular Pharmacology and ToxicologyAll applicants must possess a bachelor’s orhigher degree from an accredited college oruniversity with a grade point average of 3.0 orbetter and must have qualifying scores on theGRE. Students who have strong backgroundsin biology and/or chemistry are best suitedfor this program. Proficiency in English isessential. Whenever possible, students willbe selected for admission on the basis ofinterviews with one or more members of thefaculty.

Both the M.S. and Ph.D. programs empha-size research in molecular and neuropharma-cology, receptor pharmacology, biochemicaland oxidant toxicology. Applications foradmission are reviewed by the MolecularPharmacology and Toxicology GraduateCommittee of the School of Pharmacy andare evaluated on the basis of academic excel-lence and commitment to scientific research.

Admission Requirements for the Master ofScience in Pharmaceutical Economics andPolicyApplicants for admission must have achieveda minimum 3.0 GPA in undergraduate orprofessional school and adequate scores onthe GRE. In addition, applicants will berequired to have completed upper divisioncourses in statistical methods, calculus andmicroeconomics.

Admission Requirements for the Doctor ofPhilosophy in Pharmaceutical Economicsand PolicyCandidates with a bachelor’s, master’s orPharm.D. degree are invited to apply.Applicants must have demonstrated profi-ciency in verbal and written English and apti-tude in economics, mathematics, statisticsand computer science. Deficiencies in eco-nomics and statistical background can beaddressed through preliminary course workafter admission to the program.

A minimum grade point average of at least3.0 (A = 4.0) is required. Special attention isgiven to the grades achieved in economics,statistics and mathematics courses relevant tothe program. A qualifying score on the GREin verbal and quantitative areas is required.

Students with GRE scores of 1200 or betterwill be given priority for financial aid support.

Admission Requirements for the Master ofScience in Regulatory ScienceApplicants should possess a bachelor’s degreeor equivalent from an accredited college oruniversity. Applicants with graduate or pro-fessional degrees are encouraged to apply. Aminimum grade point average of 3.0 or quali-fying scores on the GRE or equivalent exam-ination are required. The program encour-ages the participation of part-time studentswith work experience.

Acceptance criteria for those individuals willbe assessed on a case-by-case basis. Englishproficiency is essential. Students will beselected for admission, whenever possible,after interviews with one or more members offaculty.

Admission of International Students toGraduate Degree ProgramsAll requirements described in this section arealso applicable to the admission of interna-tional students. In addition, special applica-tion and admission procedures are required ofinternational students. Refer to the sectionon Admission of International Students inthis catalogue.

Graduate Degrees 733

Degree Requirements

These degrees are under the jurisdiction ofthe Graduate School. Students should alsorefer to the Requirements for Graduationsection, page 62 and the Graduate Schoolsection of this catalogue for general regula-tions, page 601. All courses applied towardthe degrees must be courses accepted by theGraduate School.

Master of Science in PharmaceuticalSciencesA Master of Science degree in the pharma-ceutical sciences will be granted on the basisof completion of at least 24 units of formalcourse work and presentation of an accept-able thesis (PSCI 594ab, 4 units) based onthe results of an original investigation.

Master of Science in MolecularPharmacology and ToxicologyA minimum of 32 units is required includingINTD 531, INTD 561, INTD 571, andPHBI 582, MPTX 500, MPTX 501, foursemesters of MPTX 594ab and MPTX 700.

To obtain the master’s degree, studentsmay choose from two tracks. First, the non-research master’s track requires that the stu-dent carry out a detailed, extensive literature

review in an area determined by the studentin conjunction with a thesis advisor facultymember. Second, the research track requiresthat the student carry out a research projectduring the second year of the program.

On either track, during the students’ finalsemester they will prepare a thesis to com-plete their degree requirements, either cover-ing the scientific area selected in the non-research track, or describing their researchproject and results in the research track. Thethesis should be 50-100 pages on average.

Research can be initiated earlier in theprogram – in the first year or first summer.Students selecting the non-research mastertrack may elect and are encouraged to carryout research in their program.

Students are not allowed to be paid for work-ing in a lab if they are taking research or the-sis units. During the summer, faculty advisorscan provide a stipend, arranged on an individ-ual basis. Funding is not guaranteed in themaster’s program.

Master of Science in PharmaceuticalEconomics and PolicyThe Department of Pharmaceutical Econom-ics and Policy (School of Pharmacy) offers aprogram of study leading to the M.S. degree.Applicants must apply to the Graduate Schooland meet the admissions requirements of theprogram. This program requires students todemonstrate skills in the analysis of pharma-ceutical and health technology innovations,as well as an understanding of contemporaryhealth policy issues. A minimum of 36 unitsof graduate level courses is required.

Grade Point AverageA grade point average of at least 3.0 (A = 4.0)must be achieved on graduate course work atUSC.

Course RequirementsThe student is required to complete the fol-lowing 36 units of graduate level course work:ECON 414 (4 units), ECON 500 (4 units)or PPD 501 (4 units), PM 511aL (4 units), PM 512 (4 units) or approved elective,PMEP 509 (4 units), PMEP 519 (4 units),PMEP 529 (4 units), PMEP 538 (4 units) andPMEP 539 (4 units).

Students must complete all requirements forthe degree within five years of entry into theprogram.

Additional Degree RequirementsThe student must satisfactorily complete thespecified courses in economics, preventivemedicine and public administration prior toenrolling in PMEP 538 or PMEP 539. Thestudent is also required to complete anempirical research project on a topic relevantto pharmaceutical economics and policy.

Master of Science in Regulatory Science Regulatory science relates the regulatory andlegal requirements of biomedical productdevelopment to the scientific study neededto establish product safety and efficacy. AMaster of Science degree in regulatory sci-ence will be granted upon completion ofat least 30 units of formal course work and6 units of research project work in an intern-ship setting (MPTX 630). Students withexperience in industry or government cansubstitute an equivalent amount of formalcourse work for the research project with thepermission of the admissions committee.Course requirements normally include a min-imum of three courses concerned with regu-latory aspects of medical product develop-ment and a minimum of one course each inquality assurance, clinical research, business,statistics and law. Recommended course workincludes some courses available in otherdepartments of the university. Studentsshould develop a specific plan of study inconsultation with the graduate advisorsbefore beginning the program.

Doctor of Philosophy in PharmaceuticalSciencesThis program emphasizes basic as well asapplied research in drug delivery and target-ing, utilizing medicinal chemistry, computa-tional chemistry, pharmaceutics, pharmacody-namics, molecular pharmacology, immunologyand cell biology.

A minimum of 60 units is required for theDoctor of Philosophy degree. At least 24units of course work are required at the 500-level or above, exclusive of seminar anddirected research. The guidance committeemay require more than 24 units of coursework. A minimum of 12 units is to be takenin courses in the Department of Pharma-ceutical Sciences and a minimum of 8 unitsmust be taken in various related disciplinesoutside the department. The remaining36 units may be fulfilled with other courses,directed research and dissertation.

Foreign Language RequirementThere is no formal foreign language require-ment. However, an individual guidance com-mittee can require competency in a foreignlanguage or some other research tool such ascomputer language, if this is relevant for thestudent’s area of research.

Guidance CommitteeUpon admission, the student will be assignedto a member of the graduate faculty who willserve as his or her temporary advisor until apermanent advisor has been identified. Thestudent’s program of study will be under thedirection of a guidance committee composedof at least five members, one of whom mustbe from outside the department granting thedegree. The student should select a graduateadvisor and guidance committee no later thanthe third semester in residence.

Screening ProcedureThe performance of each student will beevaluated no later than the end of the secondsemester of enrollment in the graduate pro-gram. This screening procedure is conductedby the student’s guidance committee or, if astudent has not selected his or her researchadvisor at that time, by the Graduate ReviewCommittee of the department. The commit-tee reviews thoroughly the student’s progressup to that point in various areas includingcourse work, research interests and laboratoryperformance on his or her research project orlaboratory rotations. If a performance defi-ciency is detected at that point by the com-mittee, the student will be recommended toeither take additional course work or transferto the Master of Science program. Passingthis screening procedure is prerequisite tocontinuation in the Ph.D. program.

Qualifying ExaminationStudents will be required to pass a compre-hensive qualifying examination in major areasof the pharmaceutical sciences. The examina-tion is administered by the guidance commit-tee and consists of two parts: a written exami-nation and a written proposition outlining aresearch project, followed by an oral examina-tion based on the proposition and questionsdealing with the written examination.

All course and qualifying examinationrequirements for the Doctor of Philosophymust be completed within two and one halfyears after admission.

DissertationA dissertation based on original investigation isrequired. The research should make a contri-bution to science and should demonstrate thecandidate’s scholarly advancement and compe-tence to undertake independent research. Anoral defense of the dissertation will be heldafter the candidate submits the final draft ofthe dissertation to the dissertation committee

(see Graduate School policies and require-ments, page 606).

Student TeachingTeaching experience is considered an integralpart of the training of graduate students.Thus, as part of the general requirements forthe Ph.D., each student is required to partici-pate in the teaching program of the School ofPharmacy.

Doctor of Philosophy in MolecularPharmacology and ToxicologyA minimum of 60 units is required. At least24 units must be in formal course work andmust include INTD 531, INTD 561, INTD571, PHBI 582, MPTX 500, MPTX 501, andfour semesters of MPTX 700. The remaining36 units may be fulfilled with other courses,directed research and the dissertation units.Other courses selected from graduate courses(500 level or above) in pharmaceutical sci-ences, biochemistry, cell biology, chemistry,molecular biology, neuroscience, pathologyand physiology will be arranged by students inconsultation with their guidance committee.

Screening ProcedureThe progress of every student accepted intothe program is evaluated on a semester basisby the graduate affairs committee.

Language RequirementThere are no formal foreign language or com-puter language requirements. The guidancecommittee may, however, require compe-tence in a foreign language or computer lan-guage if such competence is relevant to thestudent’s research interests.

Qualifying ExaminationFollowing the successful completion of all for-mal course work (usually two years), studentsmust demonstrate excellence in general phar-macology and toxicology as well as their area(s)of research specialization. General and special-ist knowledge are tested in both written andoral qualifying examinations, which alsoinvolve the presentation of a research proposal.

DissertationAfter passing the Ph.D. qualifying examina-tions, students begin work on their disserta-tion research, which typically requires two tothree years of full-time effort. The disserta-tion research must involve original investiga-tion in a relevant scientific area and mustdemonstrate the student’s ability to plan,conduct and evaluate laboratory experiments.The dissertation research must represent asignificant contribution to knowledge andmust be successfully defended in an oralexamination. The final written dissertationmust be of publishable quality, and must beapproved by the graduate advisor and the dis-sertation committee.

734 USC School of Pharmacy

Doctor of Philosophy in PharmaceuticalEconomics and PolicyThe Department of PharmaceuticalEconomics and Policy (School of Pharmacy)offers a program of study leading to thePh.D. degree. Applicants must apply tothe Graduate School and meet admissionsrequirements. This program focuses on eco-nomic assessment of pharmaceuticals andmedical technology and research into thefinance and delivery of pharmaceuticals andpharmacy services. A minimum of 64 units ofgraduate level courses numbered 500 or high-er (excluding 794) and a minimum of fourunits of 794 is required.

Foreign Language RequirementThere is no formal foreign language require-ment. However, competence in the use ofone computer programming language isrequired for the graduate degrees. Suchcompetence can be demonstrated either bycourse work or examination.

Grade Point AverageA grade point average of at least 3.0 (A = 4.0)must have been achieved on graduate coursework at USC. ECON 615 or a higher levelcourse in econometrics must be completedwith a grade of B or higher.

Unit Requirements and Recommended CoursesStudents are required to complete a minimumof 64 units of graduate level course work. Thefollowing courses are recommended towardsfulfilling the 64-unit requirement: ECON 503,ECON 511, ECON 514, ECON 603, ECON615, PM 511a, PMEP 509, PMEP 519, PMEP529, PMEP 538, PMEP 539, PMEP 549 andPMEP 698. Students may transfer and substi-tute up to 24 units of graduate course workfrom other universities to fulfill the required64 units of graduate credit subject to theapproval of the department.

Guidance CommitteeThe student will be assigned to a memberof the graduate faculty who will serve as hisor her temporary advisor until the formationof a guidance committee. The student shouldconsult the pharmaceutical economics andpolicy director of graduate studies on theappointment of a Ph.D. guidance committeeafter taking the written qualifying examina-tion. The chairman of the student’s Ph.D.guidance committee advises the student onmatters of curriculum and graduate opportuni-ties. The guidance committee comprises threeto five members, at least one of whom mustbe from outside the department; at least twomembers must specialize in the student’s areaof emphasis; and at least three of the membersmust be suitable for service on the student’sdissertation committee. The composition of allPh.D. guidance committees must be approvedby the pharmaceutical economics and policy

director of graduate studies. The student mustform his or her guidance committee withinone month after passing the departmentalscreening procedure.

Screening ProcedureThe student’s progress will be reviewed aftereach semester and before registration forany additional course work to determine ifprogress has been satisfactory.

Seminar RequirementsEvery student is required to take and satis-factorily complete three two-unit researchseminars chosen from PMEP 698 or theequivalent. At least one of these seminarsmust be related to the student’s major fieldand the same seminar may be taken morethan once. Before completing the disserta-tion, the student must present at least oneoriginal research paper in a seminar of his orher choice. This paper should typically con-sist of original results contained in the stu-dent’s dissertation. It becomes part of thestudent’s permanent file.

Dissertation Proposal PreparationThe student is required to register for twounits of PMEP 790 and write a researchpaper on a topic suitable for a dissertation.Typically, the chair of the student’s guidancecommittee directs this work. The resultingessay becomes part of the student’s writtendissertation proposal which is presented andcritiqued during the oral portion of the quali-fying examination.

Qualifying ExaminationUpon successful completion of the first twoyears of course and grade requirements, thestudent takes a general written and oralexamination on the chosen area of researchemphasis after presenting a detailed writtendissertation proposal. After passing theseexaminations, the student is admitted to can-didacy for the Ph.D. degree.

DissertationAfter admission to candidacy, the studentforms a dissertation committee comprisingthree faculty members, one of whom must befrom an outside department. The chair ofthis committee is the dissertation supervisor.The student must register for PMEP 794each semester, excluding summer sessions,until the dissertation and all other degreerequirements are completed.

The student is expected to complete a dis-sertation based on original investigation. Thedissertation must represent a significant con-tribution to knowledge and must be defend-ed in an oral examination administered by

the dissertation committee (see the sectionon Graduate School policies and require-ments, page 606).

Student TeachingTeaching experience is considered an integralpart of the training of graduate students.As part of the general requirements for thePh.D., all students are required to undergotraining as an educator. This will include par-ticipating in seminars on educational tech-niques and hands-on teaching experiencesthrough participation in didactic and smallgroup teaching in the School of Pharmacy.

Pharm.D./Juris DoctorAdmission RequirementsAdmission to the dual Pharm.D./J.D. programis competitive, and involves meeting admis-sion requirements and gaining acceptance toboth the School of Pharmacy and the USCGould School of Law. Students will not begiven special consideration for admission toeither program because they are applying forthe dual degree. Students who have a bacca-laureate degree may apply to the dualPharm.D./J.D. degree program in two ways.First, they may apply at the time they submittheir Pharm.D. application by concurrentlysubmitting applications to both schools.Students who elect this approach must iden-tify themselves on their Pharm.D. applica-tions as potential dual Pharm.D./J.D. degreestudents. Students who are admitted to bothschools will be offered admission to the dualdegree contingent on passing all courses intheir first year of the Pharm.D. with a mini-mum 3.0 GPA. Students pursuing the dualPharm.D./J.D. degree must notify the LawSchool in a timely fashion that they will beenrolling in the dual Pharm.D./J.D. degreeprogram and will not matriculate at the LawSchool until the following year. Students whoare accepted by only one school may chooseto attend that school but will not be eligiblefor the dual degree. Second, students canapply to the dual degree by submitting anapplication to the Law School during theirfirst year of enrollment in the Pharm.D. pro-gram prior to the Law School’s publishedapplication deadline. Students who elect thisapproach must apply through the School ofPharmacy. Students who are admitted to theLaw School using this approach would beoffered admission to the dual degree contin-gent on passing all courses in their first yearof the Pharm.D. with a minimum 3.0 GPA.See the admissions section of the School ofPharmacy and the Law School for specificrequirements.

Graduate Degrees 735

736 USC School of Pharmacy

Degree RequirementsThe professions of pharmacy and law are dis-tinctly different, yet pharmacists are ofteninvolved in legal issues and lawyers frequent-ly deal with pharmacy, drug, health care,product development and toxin-related mat-ters. This dual degree program provides qual-ified students with an efficient mechanismfor obtaining the expertise and professionalcredentials that will enable them to developprofessional practices that bring togetherexpertise in both areas.

Overall RequirementsA student is required to complete all workfor both degrees within six years of the dateof matriculation at the School of Pharmacy(Pharm.D.) and five years of matriculation atthe Law School (J.D.). The entire dual degreeprogram will take six years to complete. Dualdegree students will be allowed to use 12 unitsof approved J.D. course work (elective orrequired) to meet 12 units of Pharm.D. elec-tives and 12 units of approved Pharm.D.course work (elective or required) to meetJ.D. electives. A faculty guidance committeewill determine the exact program for eachstudent, including the appropriateness ofcourses in one program used to meet electiverequirements for the other program. A total of208 units are required for the dual degree.

Pharm.D. RequirementsDual degree students must successfully com-plete 144 units of Pharm.D. and acceptableJ.D. units to receive the Pharm.D. degree.The 144 units must include 132 units ofrequired and elective pharmacy course workplus 12 units of J.D. course work deemedacceptable to meet Pharm.D. elective require-ments. Dual degree students should graduatewith their Pharm.D. degrees at the comple-tion of the first semester of the sixth academicyear of the dual degree program. Studentswill be eligible to sit for the Pharmacy BoardExams after completion of the Pharm.D.degree requirements. However, dual degreestudents will not actually be awarded theirPharm.D. degrees until they completerequirements for both degrees.

Juris Doctor RequirementsDual degree students must successfullycomplete 88 units of J.D. and acceptablePharm.D. course work during the second tosixth years of the dual degree program toreceive the J.D. degree. The 88 units mustbe composed of 76 units of J.D. course work,including satisfaction of the upper-divisionwriting requirement and any other substan-tive requirements, plus 12 units of Pharm.D.course work deemed acceptable to meet J.D.elective requirements. No J.D. credit will beawarded for Pharm.D. course work complet-ed prior to matriculation in the Law School.Students cannot receive the J.D. degreeunder requirements for the dual degree

program without prior or simultaneous com-pletion of the Pharm.D. degree.

Both professions require passing a state boardor bar exam to practice the respective profes-sions. Neither of these professional doctoraldegrees requires a thesis or comprehensivefinal exam.

Recommended ProgramPharm.D./J.D. dual degree students willbegin with the first year of the Pharm.D. cur-riculum (36 units). During the second year,students will take the first year law core(33 units), plus 3-5 Pharm.D. units. Due tothe rigor of the Law School core, pharmacycourses during the first year of Law Schoolare limited to non-science courses. The thirdthrough fifth years of the program focus onPharm.D. courses with sufficient law coursesto maintain students’ educational momentumin law. Students should complete theirPharm.D. requirements during the fall of theirsixth year of the program and their law coursework also during the sixth year. Studentsmust complete both degree requirements bythe end of the sixth year of the program.

Pharm.D./M.B.A. Dual Degree ProgramResponding to the growing demand on phar-macists to be knowledgeable in both scienceand business administration, the USC Schoolof Pharmacy in 1988 helped pioneer an inno-vation in pharmaceutical education by offer-ing this unique five-year dual degreeprogram.

The Pharm.D./M.B.A. dual degree programis offered cooperatively by the School ofPharmacy and the USC Marshall School ofBusiness. Students must complete concur-rently all requirements established by bothschools for their respective degrees.

The program involves completion of the firstyear in the School of Pharmacy, the second inthe Marshall School of Business, and thencompletion of the balance of both degreesduring the third through fifth years. A total of48 units must be completed in the MarshallSchool of Business.

First Year: Required Pharmacy School courses

Second Year: Required M.B.A. core courses

Third to Fifth Years: 108 units of Pharmacycourses and graduate business electives suffi-cient to bring the total units completed in theMarshall School of Business to at least 48.

The Pharm.D. and the M.B.A. are awardedsimultaneously upon completion of theSchool of Pharmacy and the Marshall Schoolof Business requirements.

Admission RequirementsStudents who have a baccalaureate degreefrom an accredited college or university andhave been admitted and have successfullycompleted one year in the School of Phar-macy will be considered for admission tothe Marshall School of Business. See theMarshall School of Business, page 110, foradmission requirements.

Pharm.D./M.S., GerontologyThe emerging impact of the elderly on thehealth care system has created a need forhealth care providers who understand theunique health-related needs of the elderly. Asdrug therapy remains the primary therapeuticoption for chronic disease, the demand forprescription drugs will continue to rise.There is a demand for pharmacists who areequipped to meet the pharmaceutical careneeds of this population. Geriatric pharmacyis becoming increasingly recognized as a spe-cialty. Pharmacists with expertise in gerontol-ogy and geriatrics are in an excellent positionto play a leading role in health policy anddirect patient care. The Pharm.D./M.S.,Gerontology program will provide extensiveeducation and training in the unique healthcare needs of older adults. It will allow stu-dent pharmacists with a career interest in geri-atrics or gerontology to work with health careplanning or delivery organizations to developand implement progressive pharmaceuticalcare programs for the elderly.

Application and Admission RequirementsStudents who would like to pursue the dualPharm.D./M.S. degree must be accepted byboth programs. Students applying for the dualdegree program must meet the respectiveadmission requirements for each program.This includes having completed a baccalaure-ate degree from an accredited college or uni-versity with a minimum G.P.A. of 3.0 and aminimum GRE score of 1000. Students willnot be given special consideration for admis-sion to either program because they are apply-ing for the dual degree. Students may applyto the dual Pharm.D./M.S. degree program intwo ways. First, they may apply at the timethey submit their Pharm.D. application byconcurrently submitting applications to bothprograms. Students who elect this approachmust identify themselves on both applicationsas potential dual degree students. Studentswho are admitted to both programs will beoffered admission to the Pharm.D. and willbe offered admission to the dual degree pro-gram contingent on passing all courses in theirfirst year of the Pharm.D. with a minimum3.0 G.P.A. Students who are accepted only byone program may choose to attend that pro-gram, but will not be eligible for the dualdegree. Second, students can apply to thedual degree by submitting an application tothe M.S. program during their first year of

Graduate Degrees 737

enrollment in the Pharm.D. prior to the M.S.published application deadline. Students whoelect this approach must apply through theSchool of Pharmacy. Students admitted tothe M.S. program using this approach will beoffered admission to the dual degree contin-gent on passing all courses in their first yearof the Pharm.D. with a minimum 3.0 G.P.A.Students accepted to the dual degree programmust maintain a minimum 3.0 G.P.A. in theirGerontology and Pharm.D. courses.

Recommended ProgramFirst year: Required Year I Pharm.D. coursework.

Second year: Required Gerontology coursework.

Third year: Required Year II Pharm.D. coursework.

Fourth year: Required Year III Pharm.D.course work.

Fifth year: Required Year IV Pharm.D. coursework.

Graduation RequirementsStudents must complete all requirements forthe Pharm.D. (see pages 729-732) and M.S.,Gerontology degrees as listed in the currentcatalogue with a minimum cumulative 3.0G.P.A. The specific M.S. course requirementsfor the dual Pharm.D./M.S. degree are listedon page 593.

Pharm.D./Master of Public HealthThe School of Pharmacy and the Master ofPublic Health program, in recognition of therapidly changing health care environment, andin response to the growing demand for phar-macists who are knowledgeable in both phar-macy and population-based health care issues,have developed a dual degree program. Thejoint Pharm.D./M.P.H. degree will enablegraduates to be more responsive to today’shealth care needs and will provide training forpharmacists who seek to be agents of changewithin the profession and to assume leader-ship roles in the pharmacy field and in publichealth at the local, state and national levels.

Students who are enrolled in the School ofPharmacy must apply to the Master of PublicHealth program no later than January of theirfirst year. All requirements for admission tothe regular M.P.H. program must also be ful-filled by dual degree applicants.

The Pharm.D./M.P.H. program spans fiveyears (four years of pharmacy school coursesand one year of public health courses).

Students begin the core M.P.H. courses fol-lowing the successful completion of the firstyear of pharmacy school. The last three yearsof the program are devoted to course workand the clinical rotations of the School ofPharmacy and to the completion of the elec-tive courses and practicum (field experience)of the M.P.H. program. At the conclusion ofthe joint degree program, students will havecompleted 46 units in the Master of PublicHealth program and four years of courses inthe School of Pharmacy.

All students in the Pharm.D./M.P.H. programmust meet course requirements, grade pointaverage requirements and program residencyrequirements of both programs. Students musthave a cumulative GPA of 3.0 in the Pharm.D.curriculum and a 3.0 in the M.P.H. curriculumto meet graduation requirements.

The Pharm.D. and the M.P.H. degrees areawarded simultaneously upon completion ofthe School of Pharmacy and the Master ofPublic Health requirements.

Admission Requirements and ProceduresStudents applying for the dual degree programmust meet the respective admission require-ments for each program. This includes havingcompleted a baccalaureate degree from anaccredited college or university with a mini-mum GPA of 3.0 and having acceptable GREand TOEFL scores as applicable. Studentswill not be given special consideration foradmission to either program because they areapplying for the dual degree. Students mayapply to the dual Pharm.D./M.P.H. degreeprogram in two ways. First, they may apply atthe time they submit their Pharm.D. applica-tion by concurrently submitting applicationsto both programs. Students who elect thisapproach must identify themselves on bothapplications as potential dual degree students.Students who are admitted to both programswill be offered admission to the Pharm.D. andwill be offered admission to the dual degreeprogram contingent on passing all courses intheir first year of the Pharm.D. with a mini-mum 3.0 GPA. Students who are accepted byonly one program may choose to attend thatprogram, but will not be eligible for the dualdegree. Second, students can apply to the dualdegree by submitting an application to theM.P.H. program during their first year ofenrollment in the Pharm.D. prior to theM.P.H. published application deadline.Students who elect this approach must applythrough the School of Pharmacy. Studentsadmitted to the M.P.H. program using thisapproach will be offered admission to the dualdegree contingent on passing all courses intheir first year of the Pharm.D. with a mini-mum 3.0 GPA.

Pharm.D./M.S., Regulatory ScienceRegulatory science is that branch of knowl-edge which relates the regulatory and legalrequirements of biomedical product develop-ment to the scientific testing and oversightneeded to ensure product safety and efficacy.The program provides an opportunity foradvanced preparation in the fields of regula-tory affairs, quality assurance and clinicalresearch. Students must complete concur-rently all of the requirements established forthe respective degrees. The program alter-nates the courses required for the Pharm.D.program during the fall and spring terms withcourses required in summer terms for theM.S. program. Students will typically takecourses in the summers of years two-four. Upto 12 appropriate units of course work fromthe Pharm.D. program can be applied towardthe M.S. degree. The Pharm.D. and theM.S., Regulatory Science degrees will beawarded simultaneously upon completion ofrequirements for the two programs.

Application Procedure and AdmissionRequirementsStudents applying for the dual degree programmust meet the respective admission require-ments for each program and must have a bac-calaureate degree. Students will not be givenspecial consideration for admission to eitherprogram because they are applying for thedual degree. Students may apply to the dualPharm.D/M.S., Regulatory Science degreeprogram in two ways. First, they may apply atthe time they submit their Pharm.D. applica-tion by concurrently submitting applicationsto both programs. Students who elect thisapproach must identify themselves on bothapplications as potential dual degree students.Students who are admitted to both programswill be offered admission to the Pharm.D. andwill be offered admission to the dual degreeprogram contingent on passing all courses intheir first year of the Pharm.D. with a mini-mum 3.0 GPA. Students who are accepted byonly one program may choose to attend thatprogram but will not be eligible for the dualdegree. Second, students can apply to the dualdegree by submitting an application to the M.S.in Regulatory Science program during their firstor second year of enrollment in the Pharm.D.prior to the M.S. in Regulatory Science pub-lished application deadline. Students who electthis approach must apply through the School ofPharmacy. Students admitted to the M.S. inRegulatory Science using this approach will beoffered admission to the dual degree contingenton passing all courses in their Pharm.D. studieswith a minimum 3.0 GPA.

Non-Degree Programs

738 USC School of Pharmacy

Office of External Programs1985 Zonal Avenue,Los Angeles, CA 90089-9121(323) 442-2403FAX: (323) 442-3600Email: pharmce@usc.eduwww.usc.edu/pharmacy/ced

Continuing EducationThe School of Pharmacy, Office of ExternalPrograms, is a recognized provider of continu-ing pharmaceutical education, accredited bythe Accreditation Council for PharmacyEducation (ACPE) and recognized by theCalifornia State Board of Pharmacy andthroughout the United States.

The school serves as a primary educationalresource for pharmacists in California and as asupplementary resource for other health pro-fessionals and pharmacists, nationally andinternationally.

Programs are designed to educate pharma-cists about current issues in pharmaceuticalcare, practice management, therapeuticsand other topics of professional interest.Continuing education programs are held atthe School of Pharmacy, prior to many localand national association meetings, and annu-ally in Las Vegas and Hawaii.

For information concerning continuing edu-cation programs contact: Office of ExternalPrograms.

Management Development Program inHealth CareThe USC Management DevelopmentProgram in Health Care is designed for man-agers representing various areas of healthcare. This certificate program is designed toincrease the participants’ knowledge in man-agement related to health care.

The topic areas covered are intended toenhance the manager’s competence to leadand make decisions in the increasingly turbu-lent world of health care. Some of the criticalsubjects examined are outcomes assessment,capitation, integrated delivery networks,health care accounting and finance, strategicplanning, marketing and communication, thecritical role of HMOs, policy issues, healthcare trends and others.

This program is accredited for continuingeducation credit for pharmacists. For addi-tional information, call (323) 442-2403, FAX(323) 442-3600 or email pharmce@usc.edu.

Pharm.D./Doctor of PhilosophyThe Doctor of Pharmacy/Doctor ofPhilosophy (Pharm.D./Ph.D.) program isdesigned to permit qualified Pharm.D. stu-dents with a bachelor of science or equivalentdegree to pursue research training in thepharmaceutical sciences and toxicology. Astudent accepted into the joint program mustmeet all requirements for the Pharm.D., aswell as the requirements for the Ph.D. in thepharmaceutical sciences or toxicology sec-tions listed in this catalogue. A maximum of20 units from the Pharm.D. program may becredited toward the Ph.D. These units can-not, however, be substituted for the required24 units of core course work.

Application ProcedureStudents applying for the dual degree programmust meet the respective admission require-ments for each program. This includes havingcompleted a baccalaureate degree from anaccredited college or university with a mini-mum GPA of 3.0 and a minimum GRE scoreof 1000. Students will not be given specialconsideration for admission to either programbecause they are applying for the dual degree.Students may apply to the dual Pharm.D./Ph.D. degree program in two ways. First, theymay apply at the time they submit theirPharm.D. application by concurrently submit-ting applications to both programs. Studentswho elect this approach must identify them-selves on both applications as potential dual

degree students. Students who are admitted toboth programs will be offered admission to thePharm.D. and will be offered admission to thedual degree program contingent on passing allcourses in their first year of the Pharm.D. witha minimum 3.0 GPA. Students who are accept-ed by only one program may choose to attendthat program but will not be eligible for thedual degree. Second, students can apply to thedual degree by submitting an application toone of the Ph.D. programs in the School ofPharmacy during their first two years of enroll-ment in the Pharm.D. prior to the respectivepublished application deadlines for the Ph.D.programs. Students who elect this approachmust apply through the Pharm.D. program.Students admitted to the Ph.D. program usingthis approach will be offered admission to thedual degree contingent on their having main-tained a minimum 3.0 GPA in the Pharm.D.program.

Post-Pharm.D. Graduate StudiesQualified students who wish to continuegraduate studies within the School ofPharmacy upon completion of the Pharm.D.may, with permission of the dean, substitutecertain Pharm.D. courses with courses neces-sary for the graduate degree so that the grad-uate program will not be delayed. Theseunits cannot, however, be substituted for the24 units of core course work.

Pharm.D./Graduate Certificate inGerontologyThis integrated program in pharmacy andgerontology prepares students with an interestin geriatric pharmacy to assume leadershiproles at academic, administrative or policylevels within the profession. The programinvolves the completion of 16 units of core areacourses in physiology, psychology, sociologyand social policy aspects of aging offered bythe USC Leonard Davis School of Gerontol-ogy. In addition, students are required to com-plete 8 units of approved elective courses ingerontology or geriatric pharmacy to be credit-ed toward the requirements for the Pharm.D.and the Graduate Certificate in Gerontology.It is expected that the program can be success-fully completed by candidates taking electivesin geriatric pharmacy or gerontology duringthe regular semester and completing one corecourse in gerontology during each summer inthe four year Pharm.D. program.

See the Leonard Davis School of Gerontology,page 592, for complete requirements.

Admission RequirementsStudents who have a baccalaureate degreefrom an accredited college or university mustsubmit separate applications to the School ofPharmacy and the Leonard Davis School ofGerontology. All requirements for admissionto the regular Pharm.D. program must befulfilled by the candidate. GRE scores arenot required for admission to the certificateprogram.

MOLECULAR PHARMACOLOGY ANDTOXICOLOGY (MPTX)

The terms indicated are expected but are notguaranteed. For the courses offered during anygiven term, consult the Schedule of Classes.

462 Physiology for the Health Professions(4) (Enroll in PHBI 462)

500 Molecular Pharmacology and Toxicology I (4, Fa) This is the first part of atwo-semester introductory and survey coursefor the molecular pharmacology and toxicol-ogy degree program. Prerequisite: knowledgeof biochemistry.

501 Molecular Pharmacology and Toxicology II (4, Sp) The second part of thetwo-semester course covers the generalaspects of molecular pharmacology and toxi-cology on the basis of biochemical, molecular,biological and environmental approaches.Prerequisite: MPTX 500.

511 Introduction to Medical Product Regulation (3, Sm) Introduction to regulatoryenvironments surrounding medical productdevelopment, manufacturing and marketing;operation of federal, state and internationalregulatory bodies. Recommended preparation:undergraduate degree in pharmacy, medicineor independent health sciences, engineeringor equivalent mix of post-secondary trainingand industry experience.

512 Regulation of Pharmaceutical andBiological Products (3, Sm) Ensuring safetyand effectiveness of new drugs and biolog-ics; marketing and monitoring approvedpharmaceutical/biological products; manage-ment of genetically engineered products. Recommended preparation: undergraduatedegree in pharmacy, medicine or independenthealth sciences, engineering or equivalentmix of post-secondary training and industryexperience.

513 Regulation of Medical Devices andDiagnostics (3, Sm) Development and test-ing of new medical products according toU.S. and international regulatory require-ments. Recommended preparation: undergradu-ate degree in pharmacy, medicine or inde-pendent health sciences, engineering orequivalent mix of post-secondary trainingand industry experience.

514 Regulation of Food and Dietary Supplements (3, Sm) Regulation and testingof foods, food additives and dietary supple-ments in the U.S. and abroad. Recommendedpreparation: undergraduate degree in phar-macy, medicine or independent health sci-ences, engineering or equivalent mix of post-secondary training and industry experience.

515 Quality Systems and Standards (3, Sm)Principles of quality assurance and qualitycontrol for medical-product development andmanufacture. Recommended preparation: under-graduate degree in pharmacy, medicine orindependent health sciences, engineering orequivalent mix of post-secondary training andindustry experience.

516 Medical Products and the Law (3, Fa)Legal issues affecting intellectual property,medical product development, marketing andsafety, taught through case studies and lec-tures. Recommended preparation: undergradu-ate degree in pharmacy, medicine or inde-pendent health sciences, engineering orequivalent mix of post-secondary training andindustry experience.

517 Structure and Management of ClinicalTrials (4, FaSpSm) Development and execu-tion of clinical trials: bioethical principles,good clinical practices, project managementand documentation.

518 Writing Regulatory Drug Submissions(3, Sp) Developing form and content forinvestigational drug applications, new drugapplications, biologic licensing applications toFDA; common technical documents; consid-erations of writing style.

519 Global Regulation of Medical Products(3, Fa) Regulatory requirements governingmedical products in European Union, Asiaand other global markets.

520 Risk Management for Health CareProducts (3, Sp) Risk assessment and man-agement techniques, including FMEA,HACCP, HAZAP, human factors analysis;policies, regulations, requirements and stan-dards; loss control and liability prevention.

521 Seminars in Regulatory Sciences (1, FaSpSm) Current problems in regulatoryaffairs, legal management, preclinical andclinical testing, scientific evaluation and qual-ity assurance. Graded CR/NC.

531 Cell Biology (4) (Enroll in INTD 531)

561 Molecular Genetics (4, Sp) (Enroll inINTD 561)

562 Systems and Integrative Physiology (4, Sp) (Enroll in PHBI 562)

571 Biochemistry (4, Sp) (Enroll in INTD 571)

590 Directed Research (1-12, FaSpSm)Research leading to the master’s degree.Maximum units which may be applied to thedegree to be determined by the department.Graded CR/NC.

594abz Master’s Thesis (2-2-0, FaSpSm)Credit on acceptance of thesis. GradedIP/CR/NC.

599 Special Topics (2-4, max 8) Specialtopics in Molecular Pharmacology andToxicology.

602 Science, Research and Ethics (2, Fa)A discussion of the unique technological andphilosophical issues that challenge modernscientists and a discernment of ethicalresponses to those challenges.

603 Molecular Mechanisms for BiologicalSignals (4, Fa) Biological mechanisms of hor-mone, neuro-transmitter, growth factor andxenobiotic actions from ligand-receptor inter-actions, signal transductions, modificationprocesses to regulation of gene expressionand cellular growth. Prerequisite: knowledge ofphysiology and biochemistry.

605 Toxicology of Oxidants and Free Radicals (2, Sp) The chemistry, biochemistry,and physiology of oxygen and the biochemi-cal mechanism of tissue-specific oxygen toxi-city. Prerequisite: knowledge of biochemistry.

606 Pulmonary Toxicology (2, Sp) Currentconcepts of inhalation toxicology and toxicmechanisms leading to lung injury. Lecturesinclude basic pulmonary anatomy and physi-ology. Prerequisite: knowledge of biochemistry.

630 Directed Field-Research Project(6, FaSpSm) Research/policy analysis con-ducted under preceptor supervision in anindustrial or governmental setting. Open tostudents who have completed the majority ofcourse credits in the Regulatory Science pro-gram. Graded CR/NC.

700 Seminar in Molecular Pharmacologyand Toxicology (1, max 8, FaSp) Contempo-rary advances in molecular pharmacology andtoxicology research. Registration requiredduring each year of residency.

Courses of Instruction 739

Courses of Instruction

790 Research (1-12, FaSpSm) Researchleading to the doctorate. Maximum unitswhich may be applied to the degree to bedetermined by the department. GradedCR/NC.

794abcdz Doctoral Dissertation (2-2-2-2-0,FaSpSm) Credit on acceptance of disserta-tion. Graded IP/CR/NC.

PHARMACY (PHRD)

501 Pharmaceutics I (4, Fa) Introduction tophysiochemical principles of dosage forms;properties of molecules in dosage forms, sta-bility of pharmaceuticals and their interac-tions in body tissue, including computationalapproaches. Open to Doctor of Pharmacystudents only. (Duplicates credit in formerPHAR 303.)

502 Pharmaceutics II (3, Sp) Principlesinvolved in molecules movement across biolog-ical barriers. Properties, characteristics, applica-tion of homogeneous and heterogeneousdosage forms, liquid, semi-solid and solid.Open to Doctor of Pharmacy students only.(Duplicates credit in former PHAR 306L.)

503 Biological Systems I (5, Fa) Integratedteaching of anatomy, histology, physiologyand pathophysiology in organized sequence:cellular, skeletal, muscular, nervous and lym-phatic systems. Open to Doctor of Pharmacystudents only. (Duplicates credit in formerPHAR 309 and PHAR 419.)

504 Biological Systems II (5, Sp) Continuedintegration of anatomy, histology, physiologyand pathophysiology: cardiovascular, respira-tory, renal, gastrointestinal (digestive),endocrine, and reproduction systems. Opento Doctor of Pharmacy students only. (Duplicates credit in former PHAR 310 andPHAR 419.)

505 Molecular Genetics and Therapy (2, Fa)Principles of gene expression, and recombi-nant DNA methods and applications. Focuson human genetics and influence of geneticbackground on the utilization and effective-ness of specific drugs. Open to Doctor ofPharmacy students only. (Duplicates credit informer PHAR 316.)

506 Over-the-Counter Pharmacy Products(4, Sp) Facilitate patient selection of self-carehealth care products: OTC drugs, theirdosages, pharmacology, efficacy, cost, sideeffects, adverse reactions, contraindications,and interactions with other medications.Open to Doctor of Pharmacy students only.(Duplicates credit in former PHAR 331 andPHAR 332.)

507 Health Care Delivery Systems (2, Fa)Introduction to understanding the structureof the health care system. Includes healthcare financing and the role of pharmacy andthe pharmacist in health systems.

508 Pharmacy Literature Review and Statistical Analysis (2, Sp) Literature evalua-tion and biostatistics of clinical and healthservices research, and epidemiology. Empha-sis on the management of drug therapyproducts, patient outcomes, and formularydevelopment. Open to Doctor of Pharmacystudents only. (Duplicates credit in formerPHAR 319 and PHAR 366.)

509 Pharmacy Practice and Experience I(5, Fa) Introduction of principles and theapplication of pharmaceutical care in commu-nity or hospital pharmacy setting. Includescommunications, basic practice skills, careerpathways and leadership. Open to Doctor ofPharmacy students only. (Duplicates credit informer PHAR 361, PHAR 363, PHAR 365and PHAR 450.)

510 Pharmacy Practice and Experience II(4, Sp) Introduction of principles and theapplication of pharmaceutical care in commu-nity or hospital pharmacy setting. Includescalculations, drug information, and basicpractice skills. Open to Doctor of Pharmacystudents only. (Duplicates credit in formerPHAR 362, PHAR 368 and PHAR 450.)

551 Immunology (3, Fa) Basic principlesof immunology and their application to the understanding and treatment ofimmunologically-mediated diseases. Providesthe scientific basis of immunotherapy andimmunodiagnosis. Open to Doctor of Phar-macy students only. (Duplicates credit in for-mer PHAR 441.)

552 Pharmaceutics IV (3, Sp) Principles andapplications of controlled, targeted, and self-regulating drug delivery. Methods to delivertherapeutic peptides, proteins and geneticmaterials. Open to Doctor of Pharmacy stu-dents only. (Duplicates credit in formerPHAR 406.)

553 Management within Health Care Organizations (2, Fa) Management of theprofessional practice of pharmacy in orga-nized health care systems. Introduction toformulary development and outcome analy-sis. Open to Doctor of Pharmacy studentsonly. (Duplicates credit in former PHAR 431and PHAR 432.)

554 Public Health and Epidemiology (2, Sp)Introduction to epidemiology, environmentalhealth, health education, health care organi-zations and financing. Orientation to socialand governmental controls on the health caresystem. Open to Doctor of Pharmacy stu-dents only. (Duplicates credit in formerPHAR 437.)

555 Biochemical and Molecular Sites ofDrug Action (4, Fa) Basic principles of drugaction and receptor actions. Includes theirapplication to the understanding and treat-ment of disease. Provides the scientific basisof pharmaceutical action.

557 Therapeutics I (5, Fa) Integrated teach-ing of biomedicinal chemistry, pharmacology,clinical pharmacokinetics, and therapeuticsof drugs, with emphases on pharmaceuticalstreating diseases associated with the auto-nomic nervous system. Open to Doctor ofPharmacy students only. (Duplicates creditin former PHAR 403L, PHAR 414 andPHAR 418.)

559 Therapeutics II (2, Fa) Integrated teach-ing of pharmacogenomics and biotechnologywith emphasis on general principles, diagnos-tics, and future technology.

560 Therapeutics III (6, Sp) Integrated teach-ing of biomedicinal chemistry, pharmacology,clinical pharmacokinetics, and therapeuticsof drugs, with emphases on pharmaceuticalstreating diseases associated with the centralnervous system. Open to Doctor of Phar-macy students only. (Duplicates credit in for-mer PHAR 547.)

561 Parenteral Therapy Externship (2, FaSp)Drug weight/volume concentrations, dilutionsand additive volumes are calculated in com-pounding of parenteral products in variouspatient-care settings using aseptic technique.Open to Doctor of Pharmacy students only.(Duplicates credit in former PHAR 414,PHAR 460 and PHAR 545.)

562 Therapeutics IV (4, Sp) Integrated teach-ing of biomedicinal chemistry, pharmacology,clinical pharmacokinetics, and therapeutics ofdrugs with an emphasis on treating diseasesof the renal, GI and pulmonary systems.Open to Doctor of Pharmacy students only.(Duplicates credit in former PHAR 548 andPHAR 549.)

601 Therapeutics V (6, Fa) Integrated teach-ing of biomedicinal chemistry, pharmacology,clinical pharmacokinetics, and therapeutics ofdrugs, with emphases on pharmaceuticalsaffecting cardiovascular and circulatory dis-eases. CPR certification. Open to Doctor ofPharmacy students only. (Duplicates credit informer PHAR 546.)

740 USC School of Pharmacy

603 Therapeutics VI (3, Fa) Integrated teach-ing of biomedicinal chemistry, pharmacology,clinical pharmacokinetics and therapeutics ofdrugs with an emphasis on pharmaceuticalsaffecting the endocrine diseases, systems andwomen’s health. Open to Doctor of Pharmacystudents only. (Duplicates credit in formerPHAR 548 and PHAR 549.)

605 Therapeutics VII (4, Fa) Integrated teach-ing of the biomedicinal chemistry, pharmacol-ogy, clinical pharmacokinetics, and therapeu-tics of drugs; with emphasis on chemotherapyof infectious disease: bacterial, microbial,viral, parasitic, and fungal. (Duplicates creditin former PHAR 411L, PHAR 418.)

606 Therapeutics VIII (2, Sp) Advanced top-ics and clinical therapeutics of drugs, withemphases on the treatment of infectiousdisease: bacterial, microbial, viral, parasiticand fungal. (Duplicates credit in formerPHAR 411L, PHAR 418.)

607 Nutrition (2, Fa) Biomedical knowledgeis correlated with assessments of clinical case-management problems to understand theinterrelationship between nutrition and healthin both hospitalized and healthy patients.Open to Doctor of Pharmacy students only.(Duplicates credit in former PHAR 422.)

608 Therapeutics IX (2, Sp) Integrated teach-ing of biomedicinal chemistry, pharmacology,clinical pharmacokinetics and therapeutics ofdrugs, with emphases on pharmaceuticals formanaging oncological, AIDS and immuno-logical diseases. Open to Doctor of Phar-macy students only. (Duplicates credit informer PHAR 550 and PHAR 562.)

610 Therapeutics X (3, Sp) Focuses on thepharmacology, pharmacokinetics, medicinalchemistry and clinical therapeutics that applyto pharmaceutical care of pediatric, geriatricand chronic pain patients.

612 Therapeutics XI (2, Sp) Updates stu-dents on recent advances in clinical areas,prepares students for advanced practice expe-riences and assessment of clinical readinessvia a final examination. Graded CR/NC.

614 Pharmaceutical Economics and Outcome Studies (3, Sp) Economic analysisof the U.S. health care system, the pharma-ceutical industry, and the profession; eco-nomic assessment of drug therapy costs andhealth care outcomes applying pharmaco-economic research methodologies. Open toDoctor of Pharmacy students only. (Dupli-cates credit in PHAR 406 and PHAR 553.)

616 Pharmacy, Law and Ethics (3, Sp) Toprovide students with an understanding ofethical issues that arise in pharmacy practicealong with state and federal statutes, regula-tions, and pharmacy-related cases. Open toDoctor of Pharmacy students only. (Dupli-cates credit in former PHAR 552 and PHAR 554.)

651 Community Pharmacy I (3, Fa) Develop-ment of specialized knowledge and skills incommunity pharmacy practice involving loca-tion analysis, pharmacy management princi-ples, and introduction to business law con-cepts. Open to Doctor of Pharmacy studentsonly. (Duplicates credit in former PHAR 541and PHAR 555.)

652 Community Pharmacy II (3, Sp) A con-tinuation of pharmacy business law conceptsencompassing contract principles and formsof ownership, including a review of pharmacylaws, compounding principles, and OTCagents. Open to Doctor of Pharmacy studentsonly. (Duplicates credit in former PHAR 556.)Prerequisite: PHRD 651.

653 Health Systems Pharmacy I (3, Fa)Understanding formal and informal organiza-tions in institutions, managed care, diseasemanagement, health care policy and financ-ing, patients’ chart organization, and clinicalmonitoring parameters. Open to Doctor ofPharmacy students only. (Duplicates creditin former PHAR 541 and PHAR 557.)

654 Health Systems Pharmacy II (3, Sp) Recognizing resources available for druginformation, familiarity with institutional for-mularies, medication counseling, writingchart notes, and clinical activities at an off-campus health care institution. Open to Doc-tor of Pharmacy students only. (Duplicatescredit in former PHAR 558.) Prerequisite:PHRD 557.

655 Geriatric Pharmacy I (3, Fa) Specializedknowledge and skills in geriatric pharmacy,pharmacology of aging, and unique functionsof health care team providing care to theelderly patient. Open to Doctor of Pharmacystudents only. (Duplicates credit in formerPHAR 559.)

656 Geriatric Pharmacy II (3, Sp) Specializedknowledge and skills in gerontology andgeriatric pharmacy including the pathophysi-ology of selected cardiovascular, endocrine,genitourinary gastrointestinal disorders,osteoarthritis, and osteoporosis. Open to Doc-tor of Pharmacy students only. (Duplicatescredit in former PHAR 560.) Prerequisite:PHRD 559.

657 Basic Research Design (3, FaSp)Research experience to integrate researchinto Doctor of Pharmacy program. Researchfocuses on industrial, academic, or govern-ment issues. Open to Doctor of Pharmacystudents only. (Duplicates credit in formerPHAR 565.)

658 Sleep and the Pharmacologic Management of Its Disorders (3, FaSp)Overview of normal sleep manifestations, andtreatment of common sleep disorders, andthe pharmacist’s role in assessment, treat-ment, and referral. Open to Level III Doctorof Pharmacy students only. (Duplicates creditin former PHAR 570.)

659 Molecular Therapeutics: Signal Transduction (3, FaSp) Principles of molecu-lar therapeutics against signaling pathways;emphasis on biological mechanisms underlyinghormone, growth factor, and neurotransmitter-mediated gene regulation, proliferation, andcell death. Open to Level III Pharm.D. stu-dents only. (Duplicates credit in formerPHAR 573.)

660 Disease State Management I (3, FaSp)The processes required to develop diseasestate management protocols based on datadrawn from the medical research literature.Open to Level III Doctor of Pharmacy stu-dents only. (Duplicates credit in formerPHAR 571.)

661 Pharmacy Practice in Women’s Health(3, FaSp) The pharmaceutical care of womenpatients is emphasized. Therapeutic, psy-chosocial factors and current research inwomen’s health. Open to Level III Pharm.D.students only. (Duplicates credit in formerPHAR 577.)

662 Psychiatric Pharmacy Practice (3, Sp)Specialized knowledge and skills in psychi-atric pharmacy practice including child, adult,and geriatric psychopharmacology applied toinpatient and outpatient treatment. Open toLevel III Pharm.D. students only. (Dupli-cates credit in former PHAR 578.)

663 Pharmaceutical Development (3, FaSp)Examination of pharmaceutical productdevelopment process including discovery,preclinical/clinical studies, regulatory-legalissues, and marketing. Open to Doctor ofPharmacy students only. (Duplicates credit informer PHAR 566.)

664 Clinical Problem Solving (3, Sp) Integra-tion of physical assessment, laboratory tests,history-taking, and diagnosis to formulatedecisions for optimal treatment plans inspecific disease states. Open to Level IIIPharm.D. students only. (Duplicates credit informer PHAR 574.)

Courses of Instruction 741

665 Complementary/Alternative Therapeutics (3, FaSp) Examines the thera-peutic use of complementary/alternativemedicines, such as herbal medicines, homeo-pathic drugs, vitamins and other nutritionalsupplements. Open to Level III Pharm.D.students only. (Duplicates credit in formerPHAR 579.)

666 Therapeutic Drug Monitoring (3, FaSp)Application of pharmacokinetic and pharma-codynamic principles to individualize patientdrug regimens. Open to Level III Pharm.D.students only. (Duplicates credit in formerPHAR 575.)

667 Drugs of Abuse (3, FaSp) Specializedknowledge and skills in specific substanceabuse-related areas. Each area will includeaddiction, wellness, and prevention compo-nents. Open to Doctor of Pharmacy stu-dents only. (Duplicates credit in formerPHAR 568.)

668 Computing Application (3, FaSp) Specialized knowledge and skills usingcomputers in professional practice: telecom-munication protocols, typical patient data-bases in hospital and community pharmacies,drug interactions, insurance billing, inventorycontrol. Open to Doctor of Pharmacy stu-dents only. (Duplicates credit in formerPHAR 568.)

669 Health Care Needs of Special Populations (3, FaSp) Health care needs ofthe poor will be examined through participa-tion in a multidisciplinary community clinicsetting focusing on medication counselingand compliance. Open to Level III Pharm.D.students only. (Duplicates credit in formerPHAR 576.)

670 Marketing and Development in thePharmaceutical Industry (3, FaSp) Basic andadvanced strategies for marketing and devel-opment of new compounds or indication inthe pharmaceutical industry. Recommendedpreparation: PHRD 663.

701 Acute Care Clinical Practice Clerkship(6, FaSpSm) Application of pharmaceuticalcare principles to the adult patient populationin an acute care environment. Pharmacology,pharmacokinetics, and disease state manage-ment will be emphasized. Open to Doctor ofPharmacy students only. (Duplicates credit informer PHAR 601.)

702 Inpatient Psychiatric Pharmacy Clerkship (6, FaSpSm) Application of phar-maceutical care principles to the inpatientpsychiatric patient. Understanding of thetreatment of common psychiatric disorders,patient interviewing skills and health careteams. Open to Level IV Doctor of Pharmacystudents only. (Duplicates credit in formerPHAR 602.)

703 Long Term Care Clerkship (6, FaSpSm)Application of pharmaceutical care to patientsin long term care environments. Understand-ing of the therapeutic, legal and special needsof this patient population. Open to Level IVDoctor of Pharmacy students only. (Dupli-cates credit in former PHAR 603.)

704 Primary Care Clerkship (6, FaSpSm)Disease state management and pharmaceuti-cal care in ambulatory care. Modification anddesign of drug therapy regimens, participationin medical care team and direct patient care.Open to Doctor of Pharmacy students only.(Duplicates credit in former PHAR 604.)

705 Community Pharmacy Clerkship (6, FaSpSm) Pharmaceutical care principlesapplied to the community pharmacy envi-ronment. Participating in the development,implementation and outcome evaluation ofpatient care services in the community.Open to Level IV Doctor of Pharmacy stu-dents only. (Duplicates credit in formerPHAR 605.)

706 Geriatrics Clerkship (6, FaSpSm) Drugtherapy and management of geriatric patientswith a focus on unique medical, economic,and psycho-social problems of this popula-tion. Open to Level IV Doctor of Pharmacystudents only. (Duplicates credit in formerPHAR 606.)

707 Outpatient Psychiatric Pharmacy Clerkship (6, FaSpSm) Disease state manage-ment and pharmaceutical care in ambulatorymental health care. Modification and designof psychiatric therapy regimens, participationin multidisciplinary teams and patient care.Open to Level IV Doctor of Pharmacy stu-dents only. (Duplicates credit in formerPHAR 604 and PHAR 607.)

708 Inpatient Clinical Practice Clerkship (6, FaSpSm) Drug therapy in a variety ofinpatient clinical settings. Emphasis: patientmonitoring, evaluation of therapeuticresponse, and provision of drug information.(Duplicates credit in former PHAR 610.)

709 Pediatric Drug Therapy Clerkship (4-6, FaSpSm) Clinical therapeutic and phar-macokinetic concepts applied to the pediatricpatient. Unique aspects of pediatric clinicalpharmacology emphasized in treating a vari-ety of organ system diseases. (Duplicatescredit in former PHAR 611.)

710 Surgery Clerkship (6, FaSpSm) Drugtherapy in clinical situations common to sur-gical patients. The use of drugs and monitor-ing for response to treatment in surgical set-tings. Open to Level IV Doctor of Pharmacystudents only. (Duplicates credit in formerPHAR 612.)

711 Cardiovascular Drug Therapy Clerkship(6, FaSpSm) Pharmaceutical care applied tocardiac patients. The use of cardiac drugswith an emphasis on physiologic response,pharmacokinetic principles and desired treat-ment outcomes. Open to Level IV Doctor ofPharmacy students only. (Duplicates credit informer PHAR 613.)

712 Applied Clinical PharmacokineticsClerkship (6, FaSpSm) Practical experiencein applying pharmacokinetic principles topatients in the health care system. A varietyof disease states and therapeutic agents willbe reviewed. Open to Level IV Doctor ofPharmacy students only. (Duplicates credit informer PHAR 614.)

713 Drug Information Clerkship (6, FaSpSm)Practical experience and training in the useof information resources and technology toimprove patient care. Experience in informa-tion retrieval, literature evaluation, problemsolving skills and communication skillsemphasized. Open to Level IV Doctor ofPharmacy students only. (Duplicates credit informer PHAR 615.)

714 Radiopharmacy Clerkship (6, FaSpSm)Provides practical and theoretical aspects ofradiopharmacy services delivery. (Duplicatescredit in former PHAR 616.)

715 Oncology Clerkship (6, FaSpSm)Directed experiences in the use and monitor-ing of oncological drugs. (Duplicates credit informer PHAR 617.)

716 Ob-Gyn Clerkship (6, FaSpSm) Providesexperiences in disease states common to thisarea and the drug therapy managementemployed. (Duplicates credit in formerPHAR 618.)

717 Dermatology Clerkship (6, FaSpSm) Provides experiences in disease states com-mon to this area and the drug therapy manage-ment employed. (Duplicates credit in formerPHAR 619.)

718 Hospital Pharmacy Practice Clerkship(6, FaSpSm) Practical experience and trainingin the practice of hospital pharmacy. Admin-istrative, practice-based and therapeutic com-petencies emphasized. Open to Level IVDoctor of Pharmacy students only. (Duplicates credit in former PHAR 620.)

719 Pain Management Clerkship (6, FaSpSm)Pharmaceutical care principles applied topatients requiring treatment in pain manage-ment. Pharmacology, patient counseling andmanagement emphasized. Open to Level IVDoctor of Pharmacy students only.(Duplicates credit in former PHAR 623.)

742 USC School of Pharmacy

720 Critical Care Clerkship (6, FaSpSm) Drugtherapy in a critical care setting. Emphasizestherapeutic management in critically illpatients, often with multisystem failure.(Duplicates credit in former PHAR 624.)

721 Drug Utilization and Evaluation Clerkship (6, FaSpSm) Practical experienceand training in the design, implementationand evaluation instruments (DUE/MUE) tomeasure the appropriate use of therapeuticagents and the evaluation of desired therapeu-tic outcomes. Open to Level IV Doctor ofPharmacy students only. (Duplicates credit informer PHAR 625.)

722 Home Health Care Clerkship (6, FaSpSm)Practical experience in the provision of com-prehensive home intravenous and nutritionalsupport services, including fluid and electro-lyte therapy, chemotherapy, antibiotics, paincontrol and nutrition support. Open to LevelIV Doctor of Pharmacy students only. (Dupli-cates credit in former PHAR 626.)

723 Nutritional Support Clerkship (6, FaSpSm) Experiential training in thepharmacy specialty of nutritional support.Activities include: patient evaluation, devel-oping treatment plans, formula compositionand design, integration with nutritional sup-port team and consult services. Open toLevel IV Doctor of Pharmacy students only.(Duplicates credit in former PHAR 627.)

724 Advanced Community Pharmacy Clerkship (6, FaSpSm) Directed project incommunity pharmacy. (Duplicates credit informer PHAR 628.)

725 International Pharmacy Clerkship (6, FaSpSm) Practical experience and train-ing in the practice of pharmacy in the inter-national setting. Students will visit an interna-tional pharmacy practice setting and completea project. Open to Level IV Doctor of Phar-macy students only. (Duplicates credit in for-mer PHAR 629.)

726 Directed Clinical Clerkship Project I(6, FaSpSm) Directed educational oppor-tunities not presently offered as electives,e.g., research projects or new and evolvingclerkships. (Duplicates credit in formerPHAR 630a.)

727 Directed Clinical Clerkship Project II(6, FaSpSm) Directed educational oppor-tunities not presently offered as electives,e.g., research projects or new and evolvingclerkships. (Duplicates credit in formerPHAR 630b.)

728 Directed Clinical Clerkship Project III(6, FaSpSm) Directed educational oppor-tunities not presently offered as electives,e.g., research projects or new and evolvingclerkships. (Duplicates credit in formerPHAR 630c.)

729 Directed Clinical Clerkship Project IV(6, FaSpSm) Directed educational oppor-tunities not presently offered as electives,e.g., research projects or new and evolvingclerkships. (Duplicates credit in formerPHAR 630d.)

730 Acute Care Geriatrics Clerkship (6, FaSpSm) Pharmaceutical care principlesapplied to the acutely ill geriatric patientpopulation. Emphasis on drug therapy prob-lem solving, physiology, pharmacokineticsand compliance problems. Open to Level IVDoctor of Pharmacy students only. (Duplicates credit in former PHAR 631.)

731 Advanced Geriatrics Clerkship (6, FaSpSm) Directed projects and experi-ences in geriatric drug therapy. (Duplicatescredit in former PHAR 632.)

732 Pharmacy Administration Clerkship (6, FaSpSm) Principles and practices of hospi-tal pharmacy administration, managementand departmental relationships. Practicalexperiences and projects emphasized.Open to Level IV Doctor of Pharmacy stu-dents only. (Duplicates credit in formerPHAR 633.)

733 Anticoagulation Therapy Clerkship (6, FaSpSm) Management of patients requir-ing anticoagulation. Applied knowledge ofdisease pathophysiology, anticoagulant phar-macology, and laboratory methods towardsafe and effective patient outcomes. Open toLevel IV Doctor of Pharmacy students only.(Duplicates credit in former PHAR 634.)

734 Antimicrobial Therapy Clerkship (6, FaSpSm) Antimicrobial therapy, includingantibiotic selection, dosage adjustment,and outcomes assessment of patients in thehealth care setting. Open to Level IV Doctorof Pharmacy students only. (Duplicates creditin former PHAR 635.)

735 Clinical Pharmacy Research Clerkship(6, FaSpSm) Drug research administration:research design; ethics; record-keeping; andinstitutional review. Practical experience andprojects are emphasized. Open to Level IVDoctor of Pharmacy students only. (Duplicates credit in former PHAR 636.)

736 Chemical Dependency Clerkship(6, FaSpSm) The psychiatric, social, andpharmacological management of chemicaldependency. Emphasizes the inpatient, daytreatment, and outpatient components ofdetoxification and recovery. (Duplicates creditin former PHAR 637.)

737 Clinical Transplantation Clerkship(6, FaSpSm) Drug therapy to organ transplanta-tion. Emphasizes pre- and post-transplantationtherapy designed to minimize organ rejection,prevent infection, and improve survival.(Duplicates credit in former PHAR 638.)

738 Pharmaceutical Industry Clerkship(6, FaSpSm) Train within a pharmaceuticalcompany to develop an understanding ofthe drug development, research, marketingprocess. (Duplicates credit in former PHAR 639.)

739 AIDS/Immune Disorders Clerkship(6, FaSpSm) A multidisciplinary approach tothe management of AIDS and other immuno-compromised patients. Pharmacologic man-agement is directed toward opportunisticinfections, disease modifiers, and adjuvanttherapy. (Duplicates credit in former PHAR 640.)

740 Health Care Systems AdministrationClerkship (6, FaSpSm) Practical experienceand training in managed care settings andhealth care systems. Emphasis on administra-tive principles, management and health out-comes. Students will complete a project.Open to Doctor of Pharmacy students only.(Duplicates credit in former PHAR 642.)

PHARMACEUT ICAL ECONOMICS ANDPOL ICY (PMEP)

509 Research Design (4, Fa) Introduction tothe concept of research design and examplesof the variant research methods utilized inthe field. Both the conceptual and practicalissues of research including development ofthe research question, selection of appropri-ate methods, data sources and analyticapproaches to address the research questionwill be addressed.

519 Survey Research and Quality of LifeAssessment (4, Sp) Skills to develop andassess surveys which are integral in Pharma-ceutical Economics and Policy research. Prerequisite: PMEP 509; recommended prepara-tion: biostatistics, econometrics.

529 Risk, Probabilities and Preferences(4, Sp) Analysis of economic and psychologi-cal constructs of risks, probabilities, andhealth related preferences and utilities.

Courses of Instruction 743

538 Pharmaceutical Economics (4, Sm)Introduction to pharmacoeconomics withspecial emphasis on the role of pharmaceuti-cals and the pharmaceutical industry, insur-ance, managed care, regulation and pricing.Prerequisite: ECON 500.

539 Economic Assessment of Medical Care(4, Fa) Principles of cost-benefit analysisand medical cost-effectiveness analysis withapplications in medical care and the pharma-ceutical field. Prerequisite: ECON 500 andECON 581.

549 Applied Pharmacoeconometrics (4, Sp)Use of quantitative models to describe andanalyze pharmaceutical and health care mar-kets; experimental design/power calculations;survival models; multiple indicator models;qualitative and limited dependent variablesmodels; estimation and application of suchmodels to selected problems. Prerequisite:ECON 615.

590 Directed Research (1-12, FaSpSm)Research leading to the master’s degree.Maximum units which may be applied to thedegree to be determined by the department.Graded CR/NC.

594abz Master’s Thesis (2, 2, 0, FaSp) Crediton acceptance of thesis. Graded IP/CR/NC.Prerequisite: completion of all required coursework for the M.S. degree.

698 Seminar in Pharmaceutical Economicsand Policy (4, max 8, FaSp) Current researchin pharmaceutical economics and policy pre-sented by outside scholars, faculty and stu-dents. Graded CR/NC.

790 Research (1-12) Research leading to thedoctorate. Maximum units which may beapplied to the degree to be determined bythe department. Graded CR/NC.

794abcdz Doctoral Dissertation (2-2-2-2-0)Credit on acceptance of dissertation. GradedIP/CR/NC.

PHARMACEUT ICAL SC IENCES (PSC I )

462 Physiology for the Health Professions(4) (Enroll in PHBI 462)

531 Cell Biology (4) (Enroll in INTD 531)

561 Molecular Genetics (4, Sp) (Enroll inINTD 561)

562 Systems and Integrative Physiology (4, Sp) (Enroll in PHBI 562)

571 Biochemistry (4, Fa) (Enroll in INTD 571)

590 Directed Research (1-12, FaSpSm)Research leading to the master’s degree.Maximum units which may be applied to thedegree to be determined by the department.Graded CR/NC.

594abz Master’s Thesis (2-2-0, FaSp) Crediton acceptance of thesis. Graded IP/CR/NC.Prerequisite: completion of all required coursework for the M.S. degree.

599 Special Topics (2-4, max 8, FaSp) Topicsin advanced pharmaceutical sciences.

601 Molecular Biology of Gene Regulation(2, max 8) (Enroll in BIOC 601)

613L Radiobiology and Biological Effects ofRadiation (4) Effects on the cellular leveland on mammalian systems; their bearingon human exposure criteria. Lecture andlaboratory.

652L Structure Activity Relationship andDrug Design (4, 2 years, Sp) Computerizedcorrelation of biological activities with molec-ular structures and physico-chemical proper-ties of drugs and their applications in design-ing new drugs. Lecture and laboratory.

653L Spectrometry in Biomedicine (4, 2 years, Sp) Theory of spectrometry andapplications in pharmaceutical and biomed-ical sciences. Emphasis on structural identifi-cation of organic molecules, drugs and theirmetabolites of pharmaceutical interest. Lec-ture and laboratory.

654L Computer Applications in Pharmaceutical Sciences (3, 2 years, Fa)Introduction to computing facilities andcomputer applications frequently used inthe study of pharmaceutical sciences. Stu-dents receive maximal hands-on exposure tocomputing.

655 Immunopharmaceutics (2, 2 years, Fa)Lectures and discussion sessions onpharmaceutics-related immunology, includingdrugs affecting the immune system, antibod-ies and cytokines as drugs, and new develop-ments in immunobiotechnology.

661L Advanced Pharmaceutical Analysis (4, 2 years, Fa) Theory and application ofquantitative instrumental techniques to thepharmaceutical sciences. Includes principlesof chromatography, spectrophotometry, fluo-rescence, mass spectrometry and immuno-logic assays. Lecture and laboratory.

662 Advanced Pharmacokinetics (4, 2 years, Sp) Principles of pharmacokinet-ics including mathematical description ofdrug disposition processes. Emphasis ondesign and evaluation of pharmacokineticstudies and statistical analysis of parameterestimates.

663 Advanced Drug Delivery Systems (2, Fa)Design and applications of polymers, lipo-somes, micro/nanoparticles, prodrugs, andmacromolecules for parenteral, oral, trans-dermal, respiratory and CNS drug delivery. Recommended preparation: college level chem-istry and biology; prerequisite: PSCI 665.

664 Drug Discovery and Design (4, Fa)Principles of drug discovery, design and char-acterization. Mechanisms of action of majorclasses of drugs. Recommended preparation: col-lege level chemistry and biology.

665 Drug Transport and Delivery (4, Fa)Principles of cellular drug transport, in vivodrug transport, and modern drug delivery,including drug targeting. Recommended preparation: college level chemistry andbiology.

666 Molecular Structural Biology (2, Sp)Molecular structure of proteins and DNA.Structure-function relationships and structuredetermination. Recommended preparation: college level chemistry and biology.

667 Intracellular Drug Delivery and Targeting (2, 2 years, Sp) Mechanisms ofmembrane trafficking and intracellular trans-port and the utilization of these mechanismsin drug delivery and targeting. Recommendedpreparation: college level chemistry and biol-ogy, INTD 531.

671 Drug Morphology (3, 2 years, Fa) Thiscourse will examine drug metabolism interms of hepatic and extrahepatic processes.Mechanisms of bioactivation and cellular tox-icity will also be covered. Prerequisite: depart-mental approval.

756ab Seminar in Pharmaceutical Sciences(1-1, FaSpSm) Review of current pharma-ceutical and related research topics.

790 Research (1-12, FaSpSm) Researchleading to the doctorate. Maximum unitswhich may be applied to the degree to bedetermined by the department. GradedCR/NC.

791L Research (2-12, no max) Directedresearch for the M.S. thesis or Ph.D.dissertation.

794abcdz Doctoral Dissertation(2-2-2-2-0, FaSpSm) Credit on acceptance ofdissertation. Graded IP/CR/NC.

744 USC School of Pharmacy