7/26/2019 UTI in Pregnancy Case (Diagram)

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URINARY TRACT INFECTION IN PREGNANCY

Pathophysiology and Symptomatology of Acute Pyelonephritis

Uropathogenic Microorganisms entry

in the urethra (E. Coli, Klebsiella,

Proteus, Staphylococcus spp.)

Pregnancy (14thee!s " mi#pregnancy)

$acterial entry %

multiplication in the

!i#neys

NCREASED

FREQUENC

Y OF

UR NAT ON

$acterial multiplication in

Bacterial entry into the

urinary bladder

Bacterial colonization of the

distal urethra and introitus

Bacterial attachment to

epithelial cells by mannose-

resistant adhesins on the p-

mbriae( ili)

NAUSEA

&

DYSUR A

Intrinsic contractions

of the digestive tract

ABDOM NAL PA N/

FLANK PA N

CLOUDY

UR NE

PUS

CELLS:

Prostaglandin

HEADACH

FEVE

CH LL

apidmusclecontractionandrela!ation

WEAKNES

S /

ANOREX

A

Pus

Bacterial

phagocytosis by

macrophages and

"eat conservation and

increased heat

esetting of the

hypothalamic

temperature to higher

#asodilatio

elease of I$-% into

the body &uids

'hemical e!citation of

the pain receptors in

Activation of themacrophage

elease of in&ammatoryproducts (histamine

brady*inin serotonin

+icturitionStimulation ofsensory stretch

Bladder ,illing

Decreased bladder capacityto hold urine

issue

Activation of in&ammatory

elease of lipopolysaccharide

to!ins from bacterial cell

/rine Stasis0ilatation of

ureters and renal

ela!ation of themuscular layer ofthe urinary tract

'ompressing

1Progesterone/terus rise out of the

#esicoureteral

Shorter urethra

esistance to the

cleansing action of

urine &o2 and bladder

emptying by