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Warning Signs of Severe Mental Illness Kimberlee V Wilson, DO, MS Assistant Clinical Professor Director of Inpatient Services OSU-CHS Department of Psychiatry

Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

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Page 1: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Warning Signs of Severe Mental Illness

Kimberlee V Wilson, DO, MSAssistant Clinical Professor

Director of Inpatient ServicesOSU-CHS Department of Psychiatry

Page 2: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Disclosures I have nothing to disclose.

Page 3: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Serious Mental IllnessFederal definition: Person 18 or older who currently, or any time

in the past year, has had a diagnosable mental, behavioral, or emotional disorder of sufficient duration to meet diagnostic criteria specified in DSM resulting in serious functional impairment, which substantially interferes with or limits one or more major life activities, i.e., maintaining interpersonal relationships, activities of daily living, self-care, employment, and recreation.

Page 4: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Serious Mental Illness .... serious functional impairment, which

substantially interferes with or limits one or more major life activities, i.e.,

maintaining interpersonal relationships activities of daily living self-care employment recreation

Page 5: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Serious Mental Illness

Definition excludes developmental or substance use disorders, dementia, due to general medical condition.

Page 6: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Serious Mental Illness

SMIPotential to produce impairment Interfering with quality of lifeNot always severe or persistentEx: Depression, Anxiety,

Adjustment Disorder

Page 7: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Severe or Persistent Mental Illness

SPMIChronic and disablingSchizophrenia SpectrumBipolar I Disorder

Page 8: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

SMI DSM-5 Disorders Schizophrenia Spectrum and Other Psychotic

Disorders

Bipolar and Related Disorders

Depressive Disorder

Obsessive-Compulsive Disorder

Panic Disorder

Post Traumatic Stress Disorder

Eating Disorders

Page 9: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

SMI DSM-5 Disorders Schizophrenia Spectrum and Other Psychotic

Disorders * Persistent

Bipolar and Related Disorders * Persistent

Depressive Disorders

Obsessive Compulsive Disorders

Panic Disorder

Post Traumatic Stress Disorder

Eating Disorders

Page 10: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Prevalence Schizophrenia 1.1% population 2.4 Million Americans, ~ 9,000 Tulsa Metro residents

Bipolar Disorders 2.6% population 6.1 Million Americans

Depression 6.9% population 16 Million Americans

Anxiety Disorders 18.1% population 16 Million Americans

Page 11: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

0.00%2.00%4.00%6.00%8.00%

10.00%12.00%14.00%16.00%18.00%20.00%

2016 US Adult Population

2016 US Adult Population

42 Million

2.4 Million6.1 Million

16 Million

Page 12: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Severe or PersistentDSM-5 Disorders

Bipolar Disorder

Schizophrenia Spectrum Schizophreniform Schizophrenia Schizoaffective disorders Schizotypal Personality Delusional Disorder

Page 13: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

SchizophreniaPremorbid Signs

Schizoid Personality characteristics

Quiet, passive, introverted

Takes pleasure in few activities

Prefers solitary amusement (computer games, music, TV) to social activities, avoids team sports

Page 14: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

SchizophreniaPremorbid Signs

Schizoid Personality characteristics

Does not enjoy close relationships, lacks close friends or confidants

Little interest in sexual experiences with another person

Appears indifferent to praise or criticism by others

Emotional coldness, detachment

Page 15: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

SchizophreniaPremorbid Signs

Schizotypal Personality Characteristics

Ideas of reference different from delusions

Unusual perceptual experiences, including bodily illusions

Excessive social anxiety that doesn’t diminish with familiarity

Page 16: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

SchizophreniaPremorbid Signs

Schizotypal Personality Characteristics

Odd beliefs or magical thinking that influences behavior and inconsistent with subcultural norms Superstitious, belief in telepathy or clairvoyance

Odd, eccentric or peculiar behavior or appearance

Odd thinking and speech Metaphorical, stereotyped, overelaborate

Page 17: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Prodrome Age of onset Males late teens – early to mid 20s Females early 20s – mid 30s

Behavior changes often misinterpreted for young adulthood transitions, problems adapting to new school or surroundings, loss of childhood relationships

Disconnecting from people or activities previously enjoyed

Sudden onset of obsessive-compulsive behavior

Page 18: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Phases of Psychosis

Page 19: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Signs and Symptoms

Withdrawal — complete social withdrawal and loss of interest in others

Drop in functioning — An unusual drop in functioning, at school, work or social activities, such as quitting sports, failing in school or difficulty performing familiar tasks

Problems thinking — Problems with concentration, memory or logical thought and speech that is hard to explain

Page 20: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Signs and Symptoms

Increased sensitivity — Heightened sensitivity to sights, sounds, smells or touch; avoidance of over-stimulating situations

Apathy — Loss of initiative or desire to participate in any activity

Feeling disconnected — A vague feeling of being disconnected from oneself or one’s surroundings; a sense of unreality

Page 21: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Signs and Symptoms

Illogical thinking — Unusual or exaggerated beliefs about personal powers to understand meanings or influence events; illogical or childlike magical thinking

Nervousness — Fear or suspiciousness of others or a strong nervous feeling

Sleep or appetite changes — Dramatic sleep and appetite changes or decline in personal care

Page 22: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Signs and Symptoms

New preoccupation in abstract ideas, philosophy, and the occult or religious questions

Bizarre behavior and ideas

Mood changes — Rapid or dramatic shifts in feelings

Unusual affect

Page 23: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Active PhaseSchizophrenia

Two of more, each present for significant portion of time during a 1-month period, persisting for 6 months, and one must include 1, 2, or 3:1. Delusions2. Hallucinations3. Disorganized speech

1. Frequent derailment or incoherence4. Grossly disorganized or catatonic behavior5. Negative symptoms

1. Diminished emotional expression or avolition

Page 24: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Positive Symptoms

Hallucinations: Not based on real images

Auditory is most common Voices are single or multiple in conversation Often threatening, obscene, accusatory, insulting,

commanding or running commentary of patient’s life

Visual 2nd most common

Tactile, olfactory, gustatory are rare Should prompt a Neuro workup

Page 25: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Positive Symptoms

Cenesthetic Hallucinations

• Unfounded sensations of altered states in bodily organs• Burning sensation in the brain• Pushing sensation in the blood vessels• Cutting sensation in the bone marrow• Bodily distortions

Page 26: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Positive Symptoms

Illusions Distortions of real images or sensations Can occur in prodromal phase Can be substance-induced

Page 27: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Positive Symptoms Delusions: Fixed false beliefs Persecutory - being targeted by groups or authorities Grandiose – Often Self-Aggrandizing, i.e., “chosen

by God to punish the world for it’s sins”. Owns large entities, knows presidents or

celebrities Religious – tattooed Bible verses on body Somatic – implausible conditions, i.e., presence of

aliens inside the patient’s organs causing dysfunction

Page 28: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Positive Symptoms Disordered or Loosely Associated Thought Content Reflect patient’s ideas, beliefs, and interpretation of

stimuli Outside forces controlling what patient thinks or feels, or

the patient controls outside events, i.e., sunrise Thought broadcasting or insertion Receives special messages from the TV, radio, internet or

newspaper Preoccupation with invisible forces, radiation, witchcraft,

religion, esoteric, symbolic “Tulsa is a slut spelled backwards”

Page 29: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Positive Symptoms Aggression Agitation Poor impulse control Grab other’s property, change TV channels

abruptly, Throw things at others

Decreased social sensitivity Violence and Suicide attempts Often a result of command hallucinations

Page 30: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Negative Symptoms Flat affect: lack of emotion or expression

Monotone or nonspontaneous speech or Alogia

Poor self care and hygiene

Deficits in attention and memory

Thought blocking

Poverty of thought content

Page 31: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Schizoaffective Disorder

A major mood episode (depression or mania) concurrent with Schizophrenia symptoms of delusions, hallucinations, or disorganized speech or behavior.

Delusions or halluncinations for at least 2 weeks in the absence of a mood episode during the lifetime of the illness.

Page 32: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

John NashLiving with Schizophrenia

https://youtu.be/SizS1nOOeJg

Page 33: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Bipolar Related Bipolar I Disorder

Bipolar II Disorder

Major Depressive Disorder

Page 34: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Bipolar I Disorder

Page 35: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Manic Episode Distinct period of abnormally and persistently elevated,

expansive or irritable mood

Increased goal directed activity or energy

Symptoms last at least one week and present most of the day nearly every day

Page 36: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Manic Episode During mood disturbance, 3 or more of the following

symptoms are present and are a noticeable change from the usual Inflated self-esteem or grandiosity Decreased need for sleep, i.e., feels rested after only

3 hrs More talkative then usual, feels pressure to keep

talking, difficult to interrupt Flight of ideas or feels thoughts are racing

Page 37: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants
Page 38: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Manic Episode Distractibility to irrelevant external stimuli Increased goal-directed or physical activity, either socially, at work or school or sexually Excessive activity with high potential for painful

consequences, unrestrained buying sprees multiple sexual indiscretions, foolish business investments

Page 39: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Manic Episode

The mood disturbance is sufficiently severe to: Cause marked impairment in social or occupational

functioning Require hospitalization to prevent harm to self or

others Develop psychotic features

Page 40: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Depressive EpisodeMarked opposite of mania in mood and activity.

Vegetative Depressed. Sad. Blue. Empty. May not be able to describe emotion. May not be able to cry

Withdrawal. Isolates to room or bed.

Lack of energy. Retarded movements.

Page 41: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

Depressive Episode

Poor concentration or decision-making

Loss of interest or pleasure in people, activities and sex

Hopelessness. Worthlessness

Suicidal Ideation or preoccupation with death.

Page 42: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

How it feels to be Bipolar

https://www.youtube.com/watch?v=0_sv7g4ZIKM&feature=youtu.be

Page 43: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

SMI Impact Per CDC, people with serious mental illness (SMI) have a

life expectancy that is 25 years less than the general population

Depression is the leading cause of disability worldwide

Serious mental illness costs the United States an estimated $193 billion in lost earnings each year

90% of individuals who commit suicide have an underlying mental illness Suicide is the 10th leading cause of death in U.S. 2nd leading cause of death for people aged 15-24 Each day, 18-22 veterans die by suicide

Page 44: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

SMI Impact NAMI (National Alliance on Mental Health) 1 in 5 adults will experience a mental illness in a given

year 1 in 25 (10 million) live with a serious mental illness Nearly 60% of adults with a mental illness did not receive

mental health services in the previous year

Page 45: Warning Signs of Severe Mental Illness · Schizophrenia Premorbid Signs Schizoid Personality characteristics Does not enjoy close relationships, lacks close friends or confidants

References http://www.nami.org/Learn-More/Mental-Health-By-the-

Numbers

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048500/

http://www.nimh.nih.gov/health/statistics/prevalence/any-mental-illness-ami-among-adults.shtml

https://www.youtube.com/watch?v=0_sv7g4ZIKM&feature=youtu.be

https://youtu.be/SizS1nOOeJg