Curriculum Vitae of

Dr. Maged Mohamed Abdel-Hakim Barakat

Personal Data:Personal Data: Name: Maged Mohamed Abdel-Hakim Barakat

Date of Birth: February 1, 1950, Khartoum, Sudan

Nationality: Egyptian

Marital Status: Married

Phone no: Home: 37803428

Mobile: 0101868836

Work: 23628426

E- mail: maged_barakat_1950@yahoo.com

Education: -Diploma in Molecular biology from Houstun, Texasus, USA, 1999.

-Special courses in the Computer Center, Faculty of Pharmacy, and Cairo University With general grade “Excellent” in “Introduction”, Nov.26, 1988, and in “Basic Language ,”

Oct.12, 1989.- Diploma in “Educational Technology” from Baylor College, Dundee, Scotland, United Kingdom, 1983.

- Special course diploma in “Educational Technology” with general grade “Excellent” and was the first student of Cairo University, 1981.

- Ph.D. in Biochemistry, from the Department of pharmacology and Biochemistry, Faculty of Pharmacy, Cairo University, Egypt, 1981.

- Master in Biochemistry, from the Department of Pharmacology and Biochemistry, Faculty of Pharmacy, Cairo University, Egypt, 1976.

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-Special course diploma with general grade “Excellent” from Faculty of Pharmacy, Cairo University, Egypt, 1973.

- B.Sc. in Pharmacy and Pharmaceutical Sciences,1972, with general grade “Very Good with Honor”, Faculty of Pharmacy, Cairo University, Egypt.

- High School Diploma, 1967

-Preparatory School Diploma, 1964.

-Primary School Diploma, 1961.

SKILLS:SKILLS:

COMPUTER Proficient use of Microsoft® Windows Xp Proficient use of Microsoft® Word Very Good knowledge in using Microsoft® PowerPoint Very Good knowledge in using Microsoft® Excel Excellent Knowledge in using the Internet

LANGUAGES :

Arabic is the mother tongue English: excellent spoken and written

Specialty: Specialized in biochemistry; metabolic pathways, nutrition , drug toxicity , molecular biology

Positions Held:

- The constructor of the biochemistry department in the Ahram Canadian University ,2007 and Head of Biochemistry Department, Faculty of Pharmacy, Ahram Candian University from 2007 till now.

- Head of Biochemistry Department, Faculty of Pharmacy Cairo University From 2003 to 2008.

- Professor of Biochemistry since Dec.30, 1992.

- Assistant Professor of Biochemistry, Biochemistry. Department, Faculty of pharmacy, Cairo University, Egypt (1987-1992).

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- Teaching Pharmacists about “Diabetes Mellitus” at the Continuous Medical Teaching Center, Ministry of Health.

- Teaching Diploma for Biochemical Analysis, department of Pharmacology and Biochemistry, Faculty of Pharmacy, Cairo University, Egypt (1981 up till now).

- TeachingBiochemistry, Department of Pharmacology and Biochemistry, Faculty of Pharmacy, Cairo University, Egypt (1981-1987).

- Teaching Assistant in the Department of Pharmacology and Biochemistry, Faculty of Pharmacy, Cairo University, Egypt (1976-1981).

- Instructor and demonstrator in the Department of Pharmacology and Biochemistry, Faculty of Pharmacy, Cairo University, Egypt (1971-1976).

Membership Held:

1) Member of the Egyptian Pharmaceutical Association (EPA), (1972 up till now).

2) Active member of the Faculty Committee, Faculty of Pharmacy, Cairo University, (1973-1982).

3) Member of the PostGraduate Education Committee, Faculty of Pharmacy, Cairo University (1983-1985).

4) Lecturer of Continuous Medical Teaching Center, Ministry of Health.

5) Member of the Egyptian Academy of Scientific Research and Technology Since 1981.

6) Member of the Egyptian Society of Biochemistry (1981 up till now).

7) Member of the Egyptian Society of Pharmaceutical Sciences (1981 up till now).

8) Member of Pharmacopoeial Information Center (1983 up till now).

9) Member of the Egyptian Society of Clinical Chemistry (1983 up till now).

10) Member of the Egyptian Society of Tumor Marker Oncology, Faculty of Medicine, Ein-Shams University (1991 up till now).

11) Member of the Egyptian Pharmacopoeial Committee, (Dec.1991 up till now).

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Publication and Thesis:

-Recent Publications:

-''Effect of melatonin and nifedipine on some antioxidant enzymes and different energy fuels in the blood and brain of global ischemic rats" J.Pineal Res. (2002) ;33:87-94

- '' Effect of metformin , glyburide, and/or selenium on glucose hemostasis , lipid peroxidation , glutathione levels and changes in glutathione peroxidase activity in streptozotocin-induced diabetic rats''The Egyptian journal of biochemistry and molecular biology ( EJBMB) (2002) ;20:393-412

- “Aging and antioxidant systems in experimental animals” The Egyptian journal of biochemistry and molecular biology ( EJBMB) (2002) ;proceding of the 5th national conference of biochemistry and molecular biology:49-59

-Biochemical effects of chronic abuse of ergogenic AIDS in rats Arab.J.Lab.med.(2008);34:NO1:137-155

- The effects of fenugreek, liquorice, kudzu and nateglinide on hyperglycemia and associated biochemical changes in erthrocytes and kidneys of streptozotocin/nicotinamide-induced diabetic rats,The Egyptian journal of biochemistry and molecular biology ( EJBMB) (2008);26:1-27

-Ameliorative effect of rutin against atenolol induced lysosomal hydrolases disorders in rat liver The Egyptian journal of biochemistry and molecular biology ( EJBMB) (2008);26:424-439

-Effect of fenugreek, liquorice , kudzu and nateglinide on blood sugar , lipid profile , erythrocyte and lens oxidative stress biomarkers in streptozotocin/nicotinamide-induced diabetic rats

J.clin.biochem.nutr.(2008);43:1-11

-Westernized-like-diet-fed rats: effect on glucose homeostasis, lipid profile, and adipocyte hormones and their modulation by rosiglitazone and glimepiride.Journal of diabetes and its complications. (2008);Feb:1-10

Publications for Prof. Position:

1) Blood Lipids and Lipoproteins-Cholesterol : Risk Factors in Cardiovascular Diseases“Effect of Amphetamine Addiction and Amitriptyline-Thioridazine Substitution Therapy”Al-

Azhar J. Pharm. Sci., December (1987), 7, 54-67.

2) “Effect of ACTH on Nucleic Acids and Glucocorticoids Biosynthesis in Rat Adrenals”. Bull. Faculty of Pharmacy, Cairo University, (1987), 1, 115-120.

3) “Effect of Rice-Based ORS on Blood Chemistry of Diarrheic Infants”Bull. Nutr. Inst., Cairo, Egypt, (1987), 1(7), 78-97.

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4) “Lipid Changes in Tissues of Male Albino Rats Under The Effects of Rapeseed oil Feeding and of Soybean Oil Feeding in Comparison With Corn Seed Oil Feeding”. J. Bio. Med. Sci. Ther. (1988), 4 (2), 170-179.

5) “Fatty Acid Composition of Rat Liver , Aorta, and Plasma Lipids Under the Influence of Rapeseed Oil, Soybean Oil, or Corn Seed Oil Feeding” J. Bio. Med. Sci. Ther. (1988), 4 (2), 180-196.

6) “Role of Prolactin in Calcium Homeostasis” Arab J. Lab. Med., (1988), 14 (1), 55-63.7) “Effect of Lithium Therapy on Serum Alpha-, Beta- Lipoproteins, Cholesterol, and Other Lipids

in Normal and Insulin –Treated Diabetic Rats”. J. Bio. Med. Sci. Ther. (1989), 5 (4), 24-39.8) Biochemical Screening for Certain In-born Errors of Metabolism That Cause Mental

Retardation in Egyptian Children”. The New Egyptian Journal of Medicine, (1989), 3 (3), 655-661.

9) “Some Biochemical Aspects of Amitriptyline and Tranylcypromine in Normal and Forced-Swimming Stressed Rats” Arab J. Lab. Med., (1989), 15 (2), 301-310.

10)“Serum Fructosamine and -Glucouronidase Enzyme Activity in Induced Diabetic Rats”, Proceeding of XXI conference of pharmaceutical sciences at Dar El-Hekma, Cairo, Feb.24-27, 1990, P. 251-262.

11)“The Clinical Value of Squamous Cell Carcinoma Antigen and Tumor-Associated Trypsin Inhibitor in Bladder Cancer”,Egyptian Journal of Tumor Marker Oncology, (Jan. 1991), 2 (1), 79-84.

12)“Changes of Certain Enzymatic Activities in Streptozotocin-Induced Diabetic Rat”. Bull. Egypt. Soc. Physiol. Sci., (1991), 11 (1), 57-74.

13)“The Effect of Magnesium Load on Divergent Profiles of Plasma Magnesium and Blood Glucose In Diabetic Rats”. Bull. Faculty of Pharmacy, Cairo University, (1991), 29 (2), 19-23.

14)“Lithium Administration in Relation to Glucose Tolerance, Serum Lithium and Insulin in Different Types of Diabetic Patients”,The Egyptian Journal of Biochemistry, (1991), 9 (2), 331-339.

15)“Some Metabolic Aspects of Zinc Supplementation in Diabetic Subjects”. E. M. J., (May, 1991), 8 (5), 247-260.

16)“Biochemical Studies of Misonidazole (Radio-Sensitizer) on Brain Monoamines and Enzymes of Normal and Irradiated Experimental Mice in Presence of Vitamin B6 or Vitamin C as Radio-Protectors”, J. Egyptian Soc. Pharmacol. Exp. Ther., (July, 1991), 10 (3), 1067-1084.

17)“The Chemo-Protective and Radio-Protective Effects of Thiola and L-dopa Against Misonidazole and / or -Irradiation Induced Changes in Brain Monoamine Content, Mitochondrial Monoamine Oxidase, and Cytoplasmic Acetyl Choliesterase Activities in Mice”, J. Bio. med. Sci. Ther., (Sept. 1991),n 7 (3), 1-21.

18) “Some Metabolic Indicies in Iron and Non-Iron Deficiency Anaemias”,Accepted in The 6th Arab Congress of Clinical Chemistry, Oct.24-27, 1991, Monastir, Tunisia.

19) “Biochemical and Immunoserological Changes During Acute Viral Hepatitis and Recovery”, E. M. J., (Dec. 1991), 8 (12), 507-515.

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20) Training course in “Principles of Plasmid Manipulation”, attended in the National Research Center, Jan. 17 -. 21, 1993.

21) A forum on “An Introduction to Molecular Biology”, Mar. 31, 1994, El – Zeraeen Club, Dokki, Cairo, Egypt.

22) “Urinary -HCG in Benign and Malignant Urinary Tract Diseases”, Halim, A. B. ; Barakat, M. ; El-Zayat, A. M. ; Daw, M. ; El-Ahmady, O., Disease Markers, Vol. 12, 109-115 (1994).

23) ”Effect of Egyptian-Cultivated Romanian Cynara Scolymus Extract on Some Liver and Kidney Functions as Compared With Chophytol in Rats”, Hamoda, F. M. ; Barakat, M. M. A. ; Fahim, A. T. ; Morise, M. ; and Abd-El Maksoud, S. M., The Arab Journal of Laboratory Medicine, Vol. 21, No. 2, July 1995.

Publications for Ass. Prof. Position:

1) “Effect of -Adrenergic Blockers on Blood Lipid Homeostasis as a Potential Cardiovascular Risk-Index in Insulin-Treated Diabetic Rabbits”, Al-Azhar Journal of Biomedical Sciences and Therapeutics, I (I), 21-33, (1985).

2) “Effect of Some Non-Irradiated and Gamma-Irradiated Ovarian Hormones on Insulin Secretion and Plasma Lipid Pattern in Rats”, Al-Azhar Journal of Biomedical Sciences and Therapeutics, I (2), 71-84, (1985).

3) “Glucose and Lipid Metabolism in Insulin-Treated Normal Rabbits Under The Effect of Cardioselective and Non-Cardioselective - Blockers”, Al-Azhar Journal of Biomedical Sciences and Therapeutics, I (2), 125-135, (1985).

4) “Synthesis and Biological Activity of Certain Nicotinic Acid Derivatives”, Revue Roumaine De Chimie, 31 (6), 615-624, 1986.

5) “Effect of Oral Fructose Load in Children Suffering From Infective Hepatitis”, The Egyptian Journal of Biochemistry, 4(1), 286-300, 1986.

6) “Effect of Ethanol on certain Aspects of Carbohydrate Metabolismin Rats”, Bulletin of Egypt , Soc.Physiol.Sci., 6 (4),13-33, (1986).

7) “Effect of Proquazone and Pirprofen on Some Aspects of Carbohydrate Metabolism in Arthritic Rats”, Arab.J. Lab. Med., 12, 137-144 (1986).

8) “Pharmacological Studies of the Interaction of Lithium Therapy and Insulin on Some Carbohydrate Metabolism Indecies", J. Egypt. Soc. Pharmacol, Exp. Ther., 7 (1), 69-82 (1988).

9) “Effect of Soybean Feeding With and Without Zinc Supplement on Carbohydrate Metabolismin Alloxan–Diabetic Rats”, Bulletin of Faculty of Pharmacy, Cairo University, 27 (1),1-3 (1989).

10) “Possible Role of Zinc Supplement in Alloxan–Diabetic Rats Fed With Soybean on Lipid Metabolism”, Bulletin of Faculty of Pharmacy, Cairo University, 27 (1), 4 –6 (1989).

Master & PHD Thesis :

1) Master Title: “Fatty Acid Pattern of Tissue Lipids of Rats under the Influence of Administration of Some Oral Anti-Diabetics”.

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2) Ph.D. Title: “Biochemical Studies of Certain Chemical Agents Affecting testicular Metabolism”.

3) Diploma of Educational Technology, at the Educational Development Center, Dundee College of Technology, Dundee, Scotland, UK.

4) Kheir El-Din, A.A. and Barakat, M.M. (1979); “Metabolic Effects of Metformin, Glibenclamide and Fenfluramine on Lipids in Experimental Diabetes”, Triglyceride, Metabolism, Egyptian Medical Association Bulletin.

5) Hamdy, M.A., Ismail, M.A., and Barakat, M.M. (1981); “Effect of Adenosine on Epinephrine-Induced Changes in Oxygen Uptake and Glycolysis of Rat Testis In Vitro”, The Bulletin of Faculty of Pharmacy, Cairo University, Vol. XX, no. 1, p. 237-247.

Conferences Attended:

1) The Second Conference of the Union of African Societies for Pharmacology, Cairo, Oct.8-12, 1983.

2) 2nd African, Mediterranean and Near East Congress of Clinical Chemistry Regional Congress of IFCC, 1983.

3) 3rd Arab Congress, Mediterranean and Near East Congress of Clinical Chemistry, Cairo, Marriott Hotel, Nov. 20-24, 1984. (Sponsored by The World Health Organization).

4) The Second National Congress of Biochemistry, Cairo, Nov.12-14, 1985.5) 3rd Conference of the Union of African Societies of Pharmacology, (UAS Phar.), Cairo, Dec.2-3,

1987.

6) The First International Conference of the Egyptian Society of Tumor Markers Oncology, Cairo, Feb.15-17, 1988.

7) The Second International Conference of the Egyptian Society of Tumor Markers Oncology (ESTMO), and the First Mediterranean Society of Tumor Markers Oncology (MESTMO), Cairo, Marriott Hotel, 1990.

8) XXI Conference of Pharmaceutical Sciences, Dar El-Hekma, Cairo, Feb.24-27, 1990.

9) The Second Arab International Conference on AIDS, Cairo, March 3-5, 1990.

10) 6th Arab Congress of Clinical Chemistry, Monastir, Tunisia, Oct.24-27, 1991.

11) XXI Conference of Pharmaceutical Sciences, Conference Center, Nasr City, Cairo, Dec.17-19, 1991.

12) The 37th scientific congress of the Egyptian Society of Clinical Chemistry, Cairo, Dec.21-23, 1992.

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13) Attendance to the training course of the National Research Center on “Principles of Plasmid Manipulation”, Jan.17-21, 1993.

14) Attendance to the scientific forum on Molecular Biology” of the National Committee of Biochemistry, (Academy of Scientific Research and Technology), March 31, 1994.

15)Scientific Research Project in co-operation with Cairo University and Urology Dept., Faculty of Medicine, Cairo University, about “Tumor Markers in Urinary Bladder Cancer”, 1994-1996.

16) Attendance of Clinical Chemistry Conference, Syria, April 25-28, 1994.

17) The 39th Scientific Conference of the Clinical Chemistry, Sept.27-29, 1994.

18) Al-Azhar 1st International Conference on “Recent Advances in Pharmaceutical Technology and Biological Sciences”, Cairo, Dec.21, 1995.

19) The Annual Scientific Conference of the Egyptian Society of Toxicology, April 1-3, 1998.

20) Speaker in the “World Congress of Diabetes beyond glycemic control of the protective drug therapy. Sponsored by the American academy of continuing medical education Cairo – Egypt November 5-6 , 2008

Experience:

A) Teaching Experience :

1. 1972-1976, Instructor and demonstrator of Biochemistry in the Dept. of Pharmacology and Biochemistry, Faculty of Pharmacy, Cairo University, Egypt.

2. 1976-1981, Teaching assistant in the Dept. of Pharmacology and Biochemistry, Faculty of Pharmacy, Cairo University, Egypt.

3. 1981 till now, Teaching Biochemistry for undergraduates, Faculty of Pharmacy, Cairo University, Egypt.

4. 1981 till now, Teaching Biochemistry and Biochemical Analysis for postgraduates and students of undergraduates Biochemical Analysis Diploma, Dept. of Biochemistry, Faculty of Pharmacy, Cairo University, Egypt.

5. Teaching Chemical Pathology for pharmacists at the Continuous Medical Teaching Center, Ministry of Health.

6. Teaching Educational Technology for postgraduates at Cairo Univ., Egypt.7. Professor of Biochemistry in the faculty of pharmacy, Ahram Candian University.

B) Biochemical Analysis Experience:

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The sponsor of the biochemical laboratory at Khatam Al-Morsalin Medical Hospital, Giza, and in my special medical biochemical lab. In Giza 1989 till now.

Supervision on Research ThesisI) M.Sc. Thesis:

1) Mrs. Safinaz Samy Ibrahim registered on Dec.3, 1983: “Metabolic Effects of Some Non-Steroidal Anti-Inflammatory Agents on Experimental Animals”.

2) Mrs. Mona Fayez Yusuf registered on Feb.8, 1986: “The Metabolic Effect of Some Psychotropic Drugs”.

3) Mrs. Saawsan Abdel-Hamid Mohamed El-Sayed:“Metabolic Screening Tests in Patients with Mental Retardation”.

4) Mrs. Subeha Mohamed Foad: “Effect of Some Nutritional Formulae on Blood Biochemistry in Children Suffering GIT Disturbances”.

5) Mr. Mahmoud Ahmed Ali Ahmed: “Some Biochemical Parameters in Blood Suffering From Viral Hepatitis”.

6) Mrs. Maha Ahmed Hussni Abdel-Aziz: “Study of Interaction of Specified Non-Steroidal Anti-Inflammatory Drugs on Metabolic Aspects in Arthritic Rats”.

7) Mrs. Sahar Mohamed Abdel-Maksoud: “Biochemical Studies of Therapeutic Potentialities of Pharmaceutical Cynara Scolymus (Artichoke) Extracts in Experimental Animals with Special Reference To Their Usefulness As Remedy For Hepato-Renal Functional Impairment”.

8) Mrs. Mervat Ahmed Mahmoud Afifi: “Tumor Markers in Bilharzial and Bladder Cancer Patients”.

9)Mrs. Noha A.M. El-Boughdady registered on Oct.16, 1995: “Aging and Antioxidant Systems in Experimental Animals”.

12) Mrs. Mona F. Shaalan, registered on Sept.23, 1997:“Effect of Melatonin and Nifedipine on Some Brain Neurotransmitters and Certain Enzyme Systems in Ischemic Brain of Rats”.

13) Mr. Ahmed M. A. Badr registered on Sept.20, 1998:“Effect of Some Oral Hypoglycemic and Selenium on Lipid Peroxidation in Diabetic Rats”.

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14) Co-operated in the work of the thesis titled “Effects of Some Depot-Acting Contraceptives Before and After Irradiation on Plasma Lipids”, submitted by Mr. Ayman M.A. Nour El-Dein for the M.Sc. degree.

15)Co-operated in the work of the thesis titled “Blood Lipids and Lipoproteins-Cholesterol Risk Factors in Cardiovascular Diseases: Effect of Amphetamine Addiction and Amitriptyline-Thioridazine Substitution Therapy”, submitted by Mr. Fouad Fattouh, Faculty of Pharmacy, Al-Azhar Univ. for the M.Sc. degree.

All of the first nine theses mentioned were successfully approved.

II) Ph.D. Thesis :

1) Mrs. Samia A. Shouman: “Biochemical Studies on Misonidazole in Irradiated Experimental Animals”.

2) Mrs. Buthayna Abdel-Hamid: “Biochemical Studies of Certain Enzymological Systems in Diabetes Mellitus”.

3) Mr. Mahmoud A.A. Ahmed: “Coronary Heart Disease Risk Factors in Relation to Blood Lipid Pattern”.

4) Mrs. Ola S. M. Ali (lecturer in the National Research Institute): “Iron Deficiency Anemia and Urinary Catecholamines (Norepinephrine) Excretion in Children”.

5)Mrs. Mervat A. Afify, registered on Nov.25, 1993: “Relationship Between Some Antioxidants and Tryptophan Metabolites in Bladder Cancer“.

6) El-Sayed R. Abd-Allah, registered on Sept.18, 1994: “Study of Some Markers Indicating Complications of Diabetes Mellitus in Streptozotocin-Induced Diabetic Albino Rats”.

7) Mrs. Subeha Mohamed Foad, registered on Dec.24, 1994:“Assessment of Iron and Zinc Fortified Meals”.

8)Mrs. Saawsan Abdel-Hamid Mohamed El-Sayed, registered on Apr.21, 1998: “Biochemical and Molecular Diagnosis of Metachromatic Leukodystrophy in Some Egyptian Families”.

9) Mrs. Lubna M. A. Abdel-Aal registered on May 17, 1998: “Effects of Suramin and / or Gamma Irradiation Apoptosis of Ehrlich Tumor Cells”.

10) Mrs. Shereen M. R. Abdel-Aziz, registered on Dec.19, 1998:“The Protective Effect of Some Agents on Hepato-toxicity of Acetaminophen”.

11) Co-operated in the work of the thesis titled “A Correlative Study of Some Trace Elements in Diabetic Patients”, submitted by Mr. Kamal El-Dein M. Saleh for the Ph.D degree.

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